Bactroban or baneocin

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Baneocin (powder, ointment) - instructions for use, analogues, reviews, price

Release forms and composition

The range of therapeutic effects of Baneocin ointment and powder

The drug Baneocin effectively destroys the following types of microorganisms:

Table of contents:

1. Gram-positive bacteria :

  • streptococci (Streptococcus spp., Streptococcus faecalis), including hemolytic streptococcus;
  • staphylococci (Staphylococcus spp.);
  • clostridia (Clostridium spp.);
  • Corynebacterium diphtheriae;
  • Treponema pallidum (Treponema pallidum);
  • anthrax bacillus (Bacillus anthracis);
  • listeria (Listeria monocytogenes).

2. Fungi : actinomycetes (Actinomyces spp.).

3. Gram-negative bacteria :

  • neisseria (Neisseria spp., Neisseria meningitidis), including the causative agent of gonorrhea;
  • hemophilus influenzae (Haemophilus influenzae);
  • fusobacterium (Fusobacterium spp.);
  • proteus (Proteus spp.);
  • enterobacteria (Enterobacter aerogenes);
  • Klebsiella pneumoniae;
  • salmonella (Salmonella spp.);
  • shigella (Shigella spp.);
  • cholera vibrio (Vibrio cholerae);
  • E. coli (Escherichia coli);
  • mycobacterium tuberculosis (Mycobacterium tuberculosis);
  • borrelia (Borellia spp.);
  • Leptospira interrogans.

Baneocin can be used without fear that addiction will occur and resistant strains of bacteria will form. Resistance to this drug almost never develops, which makes it highly effective. The ointment and powder do not lose their pronounced antibacterial properties when they come into contact with blood or other biological fluids.

  • pustular skin lesions (boils, carbuncles);
  • purulent infections (hidradenitis, folliculitis, pyoderma);
  • abscesses;
  • to prevent the development of infectious inflammation after surgical interventions (for example, puncture of the earlobe, navel, etc.).

The ointment perfectly eliminates the source of infection (microorganism), accelerates wound healing and reduces the severity of the inflammatory process. Thanks to these properties, Baneocin can be used to treat burns.

Indications

Instructions for use

Interaction with other drugs

Baneocin during pregnancy

Baneocin for newborns - navel treatment

Baneocin for chickenpox

Baneocin for burns

Baneocin for acne - a method of treatment

Contraindications

  • severe disturbances in the functional activity of the kidneys (against the background of heart or kidney failure);
  • pathology of the vestibular apparatus;
  • pathology of the cochlea of ​​the inner ear (cochlear apparatus);
  • rupture of the eardrum;
  • extensive areas of skin damage;
  • eye pathology (powder cannot be used);
  • sensitivity or allergy to bacitracin or neomycin;
  • sensitivity or allergy in the past to any antibiotics - aminoglycosides (for example, Kanamycin, Tobramycin, Streptomycin, Gentamicin, Amikacin, etc.).
Baneocin ointment and powder should be used with caution in case of acidosis, myasthenia gravis or any pathologies of the nervous and muscular systems. These conditions are relative contraindications, since the use of the drug is possible, but under careful supervision, and if signs of deterioration appear, it is immediately discontinued.

Side effects

Analogs

  • Sponge with kanamycin;
  • Gentacyclol sponge;
  • Bactroban ointment;
  • Heliomycin ointment;
  • Gentamicin ointment;
  • Gentamicin-AKOS ointment;
  • Lincomycin ointment;
  • Lincomycin-AKOS ointment;
  • Neomycin ointment;
  • Supirocin ointment;
  • Fuzimet ointment;
  • Fucidin ointment;
  • Altargo ointment;
  • Bonderm ointment;
  • Aerosol Gentamicin;
  • Aerosol Levovinisol;
  • Aerosol Neomycin;
  • Liniment Levomycetin;
  • Liniment Levomycetin-Acri;
  • Liniment Syntomycin;
  • Levomycetin solution;
  • Gel Fuzidin;
  • Cream Fucidin
  • Fusiderm cream.

Levomekol or Baneocin?

Reviews

Reviews of the use of Baneocin for acne

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Source: http://www.tiensmed.ru/news/baneocin-p4c.html

Bactroban ointment: instructions for the drug

Staph infections in the nose are difficult to treat.

They manifest themselves as diseases such as chronic rhinitis or sinusitis.

Bacteria often show resistance to some systemic antibacterial agents, so topical antibiotic medications are widely used in the treatment of infectious diseases of the nose.

One of them is Bactroban ointment.

The instructions for this drug characterize it as a local antibiotic for the treatment of staphylococcal infections, including mesistillin-resistant strains.

Description of the drug

The active component of Baktroban is mupirocin. The uniqueness of the drug is as follows:

  • It has a dual mechanism of action on bacteria. On the one hand, it exhibits bacteriostatic properties, suppressing the growth and reproduction of microorganisms, and on the other, bactericidal properties, causing their death.
  • In addition to the effect on Staphylococcus aureus and its strains, it is also active against other microorganisms - streptococcus, Haemophilus influenzae, pertussis and Escherichia coli, Klebsiella, Neisseria, meningococci, Citrobacter and a number of others.
  • Bacteria are practically not addictive to mupiracin.
  • The local antibiotic does not enter the systemic circulation, so treatment with high doses is possible, including for patients suffering from renal and liver failure.

The ointment contains 2% active substance. Available in tubes of 15 grams for the treatment of skin infections and 3 grams as a nasal remedy. The additional components of the nasal ointment include softisan and paraffin, which prevent dryness of the nasal mucous membranes.

pharmachologic effect

Depending on the concentration of the ointment, the active component inhibits the proliferation of bacteria, stops the production of proteins in their cells, or completely destroys infectious agents. The drug acts equally effectively on both gram-positive and gram-negative bacteria. According to the instructions, Bactroban ointment has no effect on Pseudomonas aeruginosa.

The effectiveness of the drug against bacteria that are resistant to a large number of antibiotic substances has been clinically proven. The drug exhibits its activity exclusively at the site of infection. Mupirocin may enter the systemic circulation if the ointment is applied to open wounds. In this case, the substance is metabolized into monic acid and then removed from the body through the urinary tract.

What is treated with ointment

Bactroban is prescribed for local treatment of infections of human soft tissues and skin. It is used for furunculosis, impetigo, folliculitis, infections of the nasal cavity, external auditory canal and auricle.

In addition to diseases of infectious etiology, the ointment is used to treat secondary infections. For example, infection of the skin by bacteria after burns, wounds, scratches, insect bites, etc.

Bactroban is recommended for use as a preventive measure after skin injuries resulting from shallow cuts and wounds.

How to use Bactroban ointment: instructions for the treatment of skin infections

To treat bacterial skin lesions, it is convenient to use ointment packaged in 15 gram tubes. A thin layer of ointment is applied to the problem area, and, if necessary, a fixing bandage is applied on top. Manipulations are carried out two or three times a day for five to ten days. If no improvement is observed within three or four days, then the ointment is replaced with another drug.

Bactroban nasal ointment: instructions for use for adults and children

The local drug is successfully used to treat purulent forms of rhinitis, nasopharyngitis, sinusitis, ethmoiditis or frontal sinusitis. It is unlikely that it will be possible to deliver the ointment to remote corners of the sinuses, but the use of the drug will significantly reduce the bacterial load in the nasal passages, which will speed up recovery from various sinusitis.

In some cases, a bacterial infection may be asymptomatic, since the infectious agent is in a latent state. This often occurs when people become carriers of Staphylococcus aureus. Bacteria are usually detected during an exacerbation of the disease or randomly, after submitting the contents of the nose or pharynx for bacterial culture. Such carriage is also an indication for the use of Bactroban ointment.

The medication can be purchased in city pharmacies or ordered online. A distinction should be made between ointments intended for the treatment of ENT infections and the treatment of skin affected by infectious agents. To treat nasal infections, you need to purchase a medication that says “Bactroban nasal ointment” on the package; instructions for use are in the box, along with the tube.

Unlike an ointment for eliminating infections localized on the skin, the tube intended for the nose has a thin spout and a small volume of medicinal ointment - only 3 grams. The differences in the appearance of the drugs can be seen in the photo.

Instructions for use suggest the use of Bactroban nasal ointment two or three times a day. Before treatment, the nasal passages should be cleared. To do this, you need to blow your nose well, and if there is heavy discharge or dried crusts, perform the procedure of rinsing the nose.

Dosage and method of application:

  • For adults and teenagers. The ointment is introduced into the nasal passages using an applicator - a thin spout on a tube. For one nostril, you need to squeeze out enough medicine so that the ointment is the size of a match head. Next, you should inject the product into the nostril as deeply as possible, and then repeat the same with the other half of the nose. After the medicine is introduced into the nose, the wings of the respiratory organ need to be massaged, squeezing and unclenching them. Thus, the ointment is better distributed throughout the nasal passages. Treatment is carried out in a course prescribed by the attending physician, but not more than ten days.
  • Children under 12 years old. In the instructions for use, Bactroban nasal ointment is prescribed to persons over two months of age. External ointment can be used without restrictions in children of any age category.
  • Pregnant and lactating. The active component present in the nasal ointment can penetrate into the systemic circulation in negligible quantities. Therefore, this drug can be used during pregnancy. The same cannot be said for ointments that are used to treat skin infections. If it is an open wound, then the antibiotic can enter the bloodstream and harm the fetus. During the feeding period, a woman can treat small cracks in the nipples with Bactroban, but before giving the baby the breast, the nipples must be thoroughly washed with soap.

After interacting with the ointment, you should wash off any remaining medication from your hands, this will prevent the drug from getting into your eyes and mouth. If the improvements are insignificant, then local treatment can be supplemented with other dosage forms, but this should be done only with the recommendation of the attending physician.

Why Bactroban cannot be used frequently for prophylaxis

One of the indications for taking the drug is the prevention of skin and ENT infections. Preventive measures for the use of a nasal drug can be prescribed by a doctor if the patient is in a hospital setting. This measure will help avoid hospital-acquired infections. You cannot make an independent decision about disease prevention using an antibiotic drug.

The danger of unreasonable and uncontrolled use of Bactroban is that long-term use of the drug leads to an increase in the number of bacteria resistant to chemicals. That is, infectious agents begin to get used to high concentrations of the antibacterial substance, and in the future it will be much more difficult to cure diseases.

Bactroban nasal ointment: how much does it cost, when not to use and what to replace it with

In general, the drug has many advantages over its analogues. It is easy to use, acts on a wide range of infectious agents, including resistant strains, and is used to treat various diseases. But still, Bactroban nasal ointment has a number of limitations that force patients to look for similar medications.

Contraindications

The drug has only one absolute contraindication - individual intolerance to the active substance or any component of the drug.

It is strictly forbidden to use the ointment for other purposes, for example, to treat conjunctivitis or other eye diseases that are caused by pathogenic bacteria.

If the ointment accidentally gets into your eyes, you should immediately rinse them with plenty of water.

External ointment for skin infections is not recommended for treating large wound surfaces for people with kidney failure.

External ointment intended for the treatment of skin diseases should not be used internally. Reverse application is possible, but not cost effective.

Side effects

Bactroban nasal ointment is well tolerated by patients. In rare cases, itching, burning and swelling of the nasal mucosa occurs. If the drug is used on the skin, a small rash or swelling may appear. If such symptoms appear, this indicates the presence of an allergic reaction to the components of the ointment.

Interaction with other medications

When treating with Bactroban nasal ointment, it is not advisable to use other topical medications. For example, if, simultaneously with ointment therapy, nasal drops are instilled into the nose, this will help wash out the drug and reduce the concentration of the antibiotic in the mucous membranes.

If there is a need to use another dermatological ointment, Bactroban is applied to the affected area of ​​the skin for half an hour and then thoroughly washed off. Wait at least half an hour before applying another topical product.

Price for Bactroban 15 gr. — 340 rubles, cost of nasal ointment 3 g. — 540 rubles.

Among the direct analogues of the drug, with the same active ingredient, we can name such drugs as:

  • Bonderm - price for 15 g. from 263 rubles, 3 g. — 545 rubles;
  • Supiratsin - 15 gr. costs 443 rubles.

If a patient develops allergic reactions to mupiracin, the doctor suggests other drugs that are similar in therapeutic effect to Bactroban.

These analogues include the following popular medicines:

  • Syntomycin, ointment. The active ingredient is chloramphenicol. The drug is used to treat purulent skin infections, boils, trophic ulcers, cracked nipples in nursing mothers, and infected burns. The cost of the drug is 96 rubles.
  • Levomekol, ointment. The active ingredients are methyluracil and chloramphenicol. Used to treat purulent wounds and skin diseases caused by mixed infections. The price of the drug is 144 rubles.
  • Fucidin, cream. The active substance is fusidic acid. The cream treats diseases caused mainly by staphylococcus. Indications for use include soft tissue infections, boils, folliculitis, carbuncles, and infected wounds. Unlike Bactroban nasal ointment, Fucidin is used to treat purulent eye diseases - conjunctivitis, barley and others. The cost of the drug is 490 rubles.
  • Baneocin, ointment. The active ingredients are neomycin and bacitracin. Indications for use are boils, staphylococcal sycosis, paronychia, deep folliculitis and secondary infections (eczema, wounds, dermatoses). The price of the ointment is 360 rubles.

Positive reviews prevail among patients' opinions about the drug. People note its high effectiveness and lack of side effects.

Rare negative reviews characterize the drug as an expensive product that can be replaced with cheaper analogues.

Specialty: Otorhinolaryngologist Work experience: 29 years

Specialty: Audiologist Work experience: 7 years

Source: http://gajmorit.com/nasmork/maz-baktroban-instrukcija/

Bactroban - analogues

Individual intolerance to some antibiotics, including the main component of Bactroban, mupirocin, is characteristic of people prone to allergic reactions. In such cases, it is necessary to replace the prescribed drug with another ointment with an identical mechanism of action. It turned out that it is not so easy to replace Bactroban - analogues of the drug are few, and its generics do not always have the same high effectiveness.

Analogues of external ointment Bactroban

The following ointments can be considered direct analogues of the medication in question:

These drugs are based on the same active ingredient as Bactroban - mupirocin. In addition, the concentration of the antibiotic (2%) and the main composition, including auxiliary chemical compounds, are the same.

Also, for external antimicrobial treatment of the skin, you can use synonyms and generics of Bactroban, which are similar to this ointment in terms of the mechanism of inhibition of pathogenic microorganisms and elimination of inflammatory processes. They are based on other antibiotics with a wide spectrum of activity:

3. Retamapulin. The antibiotic is presented in Altargo antimicrobial ointment.

4. Fusidic acid:

  • Fusiderm;
  • Fusicutane;
  • Fusiderm-B (additionally contains betamethasone, a corticosteroid with an anti-inflammatory effect).
  • Baneocin (a combination drug with another antibiotic - neomycin);
  • Bacitracin.

6. Tyrothricin. The ointment is called Tyrozur.

7. Syntomycin in the form of liniment.

Generics or indirect analogues of Bactroban are cheaper than the original local medicine, but no less effective, so they are more popular in dermatological practice.

Before changing the medicine, you must conduct a sensitivity test to the active components, get a detailed consultation with a doctor and recommendations on the regimen and duration of the therapeutic course.

Analogues of nasal ointment Bactroban

As for the special release form of Bactroban, intended for intranasal administration, it is more difficult to replace it.

For bacterial lesions of the nasal passages and cavities, only two direct analogues of the ointment can be used:

But this is not always possible or advisable. The cost of both substitutes for the ointment in question is approximately 3.5-4 times higher than that of Bactroban.

Copying information is permitted only with a direct and indexed link to the source

Source: http://womanadvice.ru/baktroban-analogi

Bactroban ointment - instructions for use

Bactroban ointment is a broad-spectrum antibiotic, the mechanism of which is aimed at activity against strains of Staphylococcus aureus, Staphyloccocus epidermidis, Streptococus spp. This drug with antimicrobial and bactericidal action is designed specifically for external use. The medicine is used both as an independent medicine and in complex therapy. Absorption from topical application of Bactroban ointment is negligible. That part of the active substance that enters the systemic circulation is metabolized to monic acid and then excreted in the urine.

Release form and composition of Bactroban ointment

The drug Bactroban is available in the form of external and nasal ointment 2%. The main active substance is mupirocin, which has a bacteriostatic effect. Bactroban can be used with other antibiotics, without the possibility of cross-resistance. Pathogenic bacteria rarely become accustomed to mupirocin. Excipients in the composition of the drug are macrogol, and in nasal form - mupirocin, softisan, white paraffin.

Homogeneous white ointment Baktroban is available in 15 gram tubes, which are included in the package along with an aluminum tip. The drug is stored at +25 degrees. The temperature should not be allowed to drop to freezing. The shelf life of the drug is 3 years. Available in pharmacies by prescription.

What does the ointment help with: indications for use

According to the instructions for use, Bactropan ointment helps in the local treatment of diseases of the nasal cavity, since it disrupts protein synthesis in the bacterial cell. In addition, the drug is indicated for:

  • Treatment of various skin infections (abrasions, insect bites and other infected injuries, minor burns and wounds that do not require hospitalization).
  • Prevention of complications of bacterial infections caused by wounds and cuts.

A few more uses: for herpes, acne, crusts in the nose, staphylococcus in the nose, impetigo, folliculitis, furunculosis, eczema, streptoderma, impetigo, ecthyma.

Instructions for use of Bactroban ointment (methods and dosage)

If intranasal ointment is used for the nose, then the drug is placed in the nasal passages alternately 2 times a day in small quantities. After putting the medicine in, you need to pinch your nostrils with your fingers, then rub with gentle movements on both sides. If the doctor did not say how many days to use the antibacterial ointment, then depending on the course of the disease, it should be used for 3-5 days.

The method of using Bactroban to treat an infected skin surface is slightly different. To apply, you need to use a cotton pad, onto which you apply the drug in a small dose and spread it in an even, thin layer. Then you should place the disk on the desired area and cover it with a sterile bandage. The duration of the procedure is about 1 hour, and the number of applications per day is from 1 to 3 times. The average course of treatment is a week.

After applying the ointment, in order to avoid allergic reactions, the remainder of the ointment must be washed off with water until the medicine is completely removed. If you cannot avoid contact with the eyes or other mucous membranes, you should thoroughly rinse the drug with plenty of water, otherwise severe burning and irritation of this area will occur.

Contraindications and side effects

With prolonged use or overdose of Bactroban ointment, adverse reactions such as itching, dry skin, hyperemia and burning at the application site may occur. Sometimes allergic reactions occur in the form of swelling or urticaria, and the use of nasal ointment can provoke rhinitis. The drug is contraindicated in patients with hypersensitivity to the active component. If it is present, then Bactroban needs to be replaced with similar ointments.

Use during pregnancy and lactation

During pregnancy and breastfeeding, Bactroban ointment should be used with caution, since to date there is no data from clinical studies that confirm that it is completely safe for this period of women. If it is necessary to use medication, then only if the expected benefits of treatment outweigh the risks to the health of the mother and child.

special instructions

Macrogol-based ointment should not be used in cases of severe renal failure or impaired renal function. Special conditions include the fact that long-term use of the drug leads to increased growth of microorganisms that are insensitive to it. Systemic absorption increases with severe disruption of the integrity of the skin.

If skin irritation or significant allergies occur, Bactoban therapy should be stopped or the dosage adjusted with the help of a doctor. Do not apply ointment to the drainage area. In other cases, adults and children can use the medicine without restrictions. Does not affect the ability to drive cars. Dilution of the drug leads to a decrease in its activity.

Where can I buy?

You can buy Bactroban ointment both in online pharmacies without restrictions and in pharmacy chains in any city.

  1. ZdravZona (Moscow, Kulakova St., 20).
  2. “Avicenna” (Saratov, Chernyshevsky St., 189).
  3. “Planet Health” (Rostov-on-Don, Dovatora St., 255).
  4. “Rigla” (Krasnodar, 40 Let Pobedy St., 22).
  5. No. 1 INCO-TRADE (Kiev, Galitskaya st., 13).
  6. “Don’t get sick” (Dnepropetrovsk, Kommunar railway station, 5B)
  7. “We wish you health” (Odessa, Segedskaya str., 14).
  8. “Magnolia” (Kharkov, Bronenosets Potemkina str., 16).

The price of the drug depends on the manufacturer, the pricing policy of the outlet and the region in which the medicine is sold. In 2016, the average cost in Moscow pharmacies was 700 rubles. When buying Bactroban ointment in other regions of Russia or other countries, you will spend:

  • Russia – 600 rubles;
  • Ukraine – 250 hryvnia;
  • Belarus – white rub;
  • Kazakhstan – 3200 tenge.

Structural analogues of the drug

  1. Bonderm. Prescribed for infectious skin lesions, including boils of the auricle (used at the first stage of boil maturation). Prevention of bacterial complications. Contraindicated in children under 3 years of age.
  2. Baneocin. It has proven itself in the treatment of rare focal skin infections: deep follicles, parochinia, purulent hydranitis. Used as complex therapy after operations. If you have liver failure, consult your doctor before use.
  3. Supirocin. An antibiotic used to treat skin conditions. Indicated for eczema, folliculitis, boils, purulent wounds, burns. Suitable for all ages, including children and the elderly. Side effects are very rare.

Reviews

Galina, 33 years old: I was looking for reviews on the forums about Bactroban ointment, because I first bought it for a 1-year-old child, and then I doubted it, since the composition contained an antibiotic unknown to me. A lot of positive reviews calmed me down and cured bacterial thrush in the groin in 3 days (I applied it 3 times a day). The only negative is the high price. And don’t forget to wash your hands after use, otherwise there will be a burning sensation.

Carolina, 19 years old: I experienced complications on my face (rashes clustered in groups) after a cosmetic procedure, and the cosmetologist advised me to apply Bactroban to the areas of inflammation. The drug is more like a thick gel, and after application I really wanted to scratch the problem areas. I used it for only a week and the result, as they say, was on a face that was without a single spot. True, the high concentration of antibiotic in the composition burns your hands, so you should not forget to wash them after the procedure until the residue is completely removed.

Vitalina, 49 years old: I am an experienced physician myself, so I always have Bactroban ointment at home. It is better to use a local antibiotic than to swallow such tablets orally. I like the drug because it has no resistance at all to microorganisms and other antibiotics and does not need to interact with them. If I or my loved ones have a burn, scratch, abrasion, bee sting or other household troubles, Bactroban is always at hand!

Source: http://wjone.ru/441-baktroban-maz

Bactroban

Prices in online pharmacies:

Bactroban is an antibiotic-containing ointment for external and local (in ENT practice) use.

Release form and composition

You are given Bactroban in two forms:

  1. Nasal ointment 2%. The color is white or almost white, of uniform consistency. 1 g of the drug contains 21.5 mg of mupirocin calcium, which is equivalent to 20 mg of mupirocin. The following excipients are used: white soft paraffin, softizan. Packaged in aluminum tubes of 3 g, complete with plastic tip, packaging – cardboard box;
  2. Ointment for external use 2%. The color is white or almost white, of uniform consistency. 1 g of medication contains 22 mg of mupirocin. Excipients – macrogol 400 and macrogol 3350. Packaged in aluminum tubes of 15 g, complete with plastic tip, packaging – cardboard box.

Indications for use

The use of nasal ointment is practiced for local infections of the nasal cavity caused by Staphylococcusaureus microorganisms (including methicillin-resistant strains) sensitive to mupirocin.

Ointment for external use Bactroban, according to the instructions, is recommended in the following cases:

  • Treatment of primary skin infections - folliculitis, impetigo, ecthyma, furunculosis (including boils of the auricles and external auditory canals);
  • Treatment of secondary skin infections - infected eczema, injuries, abrasions, insect bites, minor burns and wounds that do not require hospitalization;
  • Prevention of bacterial infections in small wounds and cuts.

Contraindications

The use of Bactroban, according to the instructions, is contraindicated in case of hypersensitivity to mupirocin and/or to the auxiliary components of the medication.

The ointment is used with caution for external use on large surfaces of the skin, with increased absorption of polyethylene glycol (through wounds or other damage to the epidermis) in patients with moderate and severe renal failure. Because macrogol (an excipient of the drug for external use) is polyethylene glycol, which is excreted from the body through the kidneys.

There is no data on the use of ointment during pregnancy and breastfeeding. Therefore, treatment with Bactroban is recommended only under the supervision of a doctor, if the possible risk to the child is insignificant in comparison with the benefits of therapy for his mother.

Directions for use and dosage

To apply Bactroban nasal ointment, you should use a special applicator - a reusable plastic tip.

About 30 mg of the product (the size of a match head) should be squeezed into each nostril, after which the nasal passages should be squeezed tightly so that it is evenly distributed throughout the mucous membrane. Repeat the procedure twice a day, the course duration is from 3 to 5 days.

It is not recommended to use this drug for more than 10 days and simultaneously with other intranasal medications.

Bactroban ointment for external use is distributed in small quantities onto the affected areas of the skin 2 to 3 times a day; a bandage may be applied on top. The duration of therapy can be up to 10 days, but if after a five-day course there is no effect, it is necessary to take into account the dynamics of clinical indicators and re-evaluate treatment tactics.

Fundamental clinical studies were conducted on the safety and effectiveness of using Bactroban ointment in children from two months of age. Based on the results of observations, no age restrictions have been established.

Correction of the dosage regimen is not necessary for elderly patients, as well as patients with impaired liver function.

Side effects

Therapy with Bactroban nasal ointment may cause allergic manifestations on the nasal mucosa (uncommon); local hypersensitivity reactions (very rare).

When applying Bactroban ointment for external use, the following are possible: itching and burning in the area of ​​application, contact dermatitis, erythrema, allergic rash, swelling, dry skin, and in isolated cases a generalized allergic reaction.

special instructions

You should avoid getting Bactroban ointment in your eyes, and if this happens, you should rinse them with plenty of water to completely remove the drug.

Ointment for external use should not be applied to drainage areas or mucous membranes.

If allergic skin reactions occur or significant irritation of the epidermis occurs, you should stop therapy, remove any remaining ointment by rinsing with water, and consult a doctor to prescribe alternative antibiotic drugs.

Long-term use of mupirocin can cause excessive growth of microorganisms that are insensitive to this antibiotic.

There have been no cases of negative effects of using the product on controlling complex mechanisms or driving vehicles.

After each contact with Bactroban ointment, be sure to wash your hands thoroughly.

Analogs

Preparations for external use, the main active ingredient of which is mupirocin - Supirocin, Bonderm

Analogues similar to Bactroban ointment for external use according to the mechanism of action, belonging to the same pharmaceutical industry. subgroup - Baneocin, Heliomycin, Gentamicin, Levovinisol, Levomycetin, Linkomycin, Neomycin, Syntomycin, Fuzidin, Fuzimet, Fusiderm, etc.

Bactroban nasal ointment has no direct analogues. Drugs similar in mechanism of action - Aqua Maris, Aqua-Rinosol, Aflubin-Naze, Isofra, Luffel, Marimer, Pinosol, Rizosin, Physiomer, Fluimarin, Evamenol, Nazol Aqua

Terms and conditions of storage

Tubes of ointment should be stored out of the reach of children, at a temperature not exceeding 25° C.

The shelf life of the ointment for external use is 2 years, for nasal use – 3 years.

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Bactroban 3 g nasal ointment

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Bactroban

Compound

  • 1 gram of Bactroban ointment for external use includes 22 mg of mupirocin. Additional substances: macrogol 3350, macrogol 400.
  • 1 gram of cream (Bactroban krem) for external use contains 22 mg of mupirocin. Additional substances: stearyl alcohol, xanthan gum, cetomacrogol-1000, liquid paraffin, phenoxyethanol, cetyl alcohol, benzyl alcohol, water.
  • 1 gram of Bactroban nasal ointment contains 20 mg of mupirocin. Additional substances: white paraffin, softizan 649.

Release form

  • Bactroban ointment for external use is white in color and has a uniform structure. 15 or 5 grams of ointment in an aluminum tube - one tube with an aluminum tip in a cardboard pack.
  • White, homogeneous cream for external use. 15 grams of cream in an aluminum tube - one tube with an aluminum tip in a cardboard pack.
  • Bactroban nasal ointment is white. 3 grams of ointment in an aluminum tube - one tube with a plastic tip in a cardboard pack.

pharmachologic effect

Antibacterial, bactericidal effect.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Broad-spectrum antibiotic for local external use. Mupirocin is secreted by the bacterium Pseudomonas fluorescens.

It inhibits protein synthesis in the bacterial cell through temporary binding to the enzyme isoleucyl-tRNA synthetase, resulting in the inclusion of isoleucine in the synthesized protein chains.

When used in minimal inhibitory concentrations, it has a bacteriostatic effect, and in high concentrations it has a bactericidal effect.

Due to the specific mode of action and rare chemical structure, cross-resistance with other antibiotics does not occur. When used correctly, the risk of developing resistant strains is small.

Acts on aerobic gram-positive pathogens - Staphylococcus aureus and epidermidis, other coagulase-negative representatives of the genus Staphylococcus, representatives of the genus Streptococcus; anaerobic gram-negative pathogens - Neisseria gonorrhoeae and meningitidis, Haemophilus influenzae, Branhamella catarrhalis, Proteus mirabilis and vulgaris, Pasteurella multocida, Citrobacter freundii, Enterobacter cloacae and aerogenes, Bordetella pertussis.

Drug-resistant microorganisms: representatives of the genus Corynebacterium, genus Enterobacteriaceae, genus Micrococcus, non-fermenting gram-negative cocci.

Pharmacokinetics of ointment for external use

Mupirocin penetrates poorly through intact skin, and when absorbed through the surface of a wound or burn, it is metabolized to monic acid (an inactive metabolite) and is quickly evacuated from the body by the kidneys.

Pharmacokinetics of intranasal ointment

After intranasal administration, it penetrates into the systemic bloodstream when used in newborns, without causing undesirable reactions. Mucosal absorption accounts for less than 1% of the applied dose, which is excreted in the urine in the form of monic acid.

Indications for use

Indications for use of external ointment

  • Treatment of primary skin infections: folliculitis, impetigo, furunculosis, ecthyma.
  • Treatment of secondary skin infections: infected, infected injuries, eczema, minor burns and wounds.
  • Prevention of bacterial complications arising from minor wounds and cuts.

Indications for use of intranasal ointment

  • Local infections of the nasal cavity caused by microorganisms sensitive to the drug.

Contraindications

  • Allergy to medication components.
  • Ointments containing macrogol cannot be used on large surfaces in conditions characterized by increased absorption of polyethylene glycol, mainly in renal failure.

Side effects

In general, Bactroban ointment is well tolerated. Rarely, allergic skin reactions may occur in the area of ​​application: rash or swelling. Even more rarely, burning, itching in the area of ​​application, erythema, swelling, dry skin, contact dermatitis are possible. Generalized allergic phenomena occur in episodic cases.

Instructions for use of Bactroban (Method and dosage)

External ointment Bactroban, instructions for use

The ointment is used externally up to three times a day. A small volume of ointment is squeezed out of the tube and applied to the affected area of ​​the skin; a bandage may be applied on top. After using the drug, you should wash your hands well. The average duration of therapy (depending on the severity of the diagnosis) is no more than 10 days. If there is no effect after 5 days of drug therapy, it is recommended to change treatment tactics taking into account the dynamics of clinical data.

Instructions for using the cream are completely identical to the instructions for the ointment described above.

Intranasal ointment Bactroban, instructions for use

The ointment is administered using an applicator. To do this, a small volume of medication (a ball about 2 mm in diameter) is injected into each nasal passage twice a day. The nasal passages must be compressed tightly, causing the ointment to be distributed more evenly throughout the nasal mucosa.

The duration of treatment is approximately 3-5 days. It is prohibited to use the drug for more than 10 days in a row without assessing the effectiveness of treatment. It is also prohibited to mix Baktroban with other products for intranasal use due to the possible dilution of the ointment and a decrease in antibacterial activity or a change in its stability.

Overdose

There is no data on the possibility of drug overdose.

Interaction

The described medicine should not be combined with other external drugs due to the risk of its dilution, which may cause a decrease in antibacterial activity and loss of stability of the dosage form.

Terms of sale

Storage conditions

Store at room temperature. Keep away from children.

Best before date

special instructions

It is forbidden to apply the external agent to the mucous membranes and treat the tissues around the drainage.

It is necessary to avoid getting the medicine into the eyes, and if this does happen, the eye must be thoroughly rinsed with clean water until the remaining ointment is completely washed away.

In very rare cases of the development of allergic reactions or skin irritation after using the drug, it is recommended to stop treatment, rinse the affected area with plenty of clean water and prescribe an alternative antibacterial treatment.

Long-term use of the drug can lead to strong growth of insensitive flora.

There was no negative effect of the drug on the ability to drive vehicles.

Analogs

Analogues of Bactroban for external use: Altargo, Baneocin, Bonderm, Chitosan-Ghent, Levomycetin.

Analogs of nasal ointment: Supirocin, Bioparox.

For children

This category of patients has no restrictions on the use of the medicine.

During pregnancy and lactation

The use of the drug during these periods under the supervision of a physician cannot be ruled out.

Reviews about Bactroban

The instructions allow the use of Bactroban nasal ointment for children. The reviews are no different from the reviews of adults. The ointment helps well with all the pathologies listed in the indications and causes almost no adverse effects.

Bactroban price, where to buy

The price of external ointment 15 g in Russia can range from 220 to 420 rubles, and the price of Bactroban nasal ointment can reach rubles.

In Ukraine, the price of the release form for external use in a 15 gram tube is equal to hryvnia. The nasal release form of the same name costs on average hryvnia.

  • Online pharmacies in Russia Russia
  • Online pharmacies in Ukraine Ukraine

Pharmacy 36.6

ZdravZone

Bactroban 15g ointment Glaxo Operations UK Ltd

Bactroban 3 g nasal ointment Glaxo Operations UK Ltd

Pharmacy IFC

Pharmacy24

Bactroban Glaxo Operations UK (UK)

Bactroban Glaxo Operations UK (UK)

PaniPharmacy

Information about medications on the site is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment. Before using the drug Bactroban, be sure to consult with your doctor.

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The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

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Source: http://cdoctor.ru/baktroban/

The drug "Baneocin": reviews from doctors

How effective is the drug "Baneocin"? Reviews about this product, its release form, indications and contraindications will be presented below. We will also tell you how to use the mentioned medication, whether it has analogues and side effects.

Composition, packaging, description and release form

This medication can be purchased in two different forms:

  • "Baneocin" powder. Instructions for use and reviews state that this type of drug is sold in polyethylene jars equipped with a dispenser (10 g each). The medicinal powder has a fine structure and is also white in color (may be slightly yellowish). The active ingredients of this drug are two antibiotics - neomycin and bacitracin. Corn starch and magnesium oxide are used as additional ingredients.
  • Ointment "Baneotsin". Reviews indicate that this type of medication can be purchased in aluminum tubes of 20 g. The active elements of this form are also neomycin and bacitracin. Soft white paraffin and lanolin are used as additional substances.

Pharmacological features

What properties does the drug “Baneocin” have? Reviews from experts indicate that this is a combined antibacterial agent intended for local use.

The medication contains two antibiotics that have a bactericidal effect.

Neomycin is an aminoglycoside antibiotic. It is able to inhibit the synthesis of bacterial proteins. This substance is active against both gram-negative and gram-positive microorganisms.

Bacitracin is a polypeptide antibiotic. It inhibits the synthesis of bacterial cell walls. This component exhibits particular activity against some gram-negative microorganisms and all gram-positive ones. It should also be noted that resistance to bacitracin is very rare in humans.

Thus, the combination of antibiotics in one drug allows you to act on many microorganisms and bacteria.

Pharmacokinetic parameters

Is Baneocin absorbed into the systemic circulation? Reviews from doctors say that the active components of this product are not absorbed even if there is damage to the skin. However, after using this drug, fairly high concentrations of the drug may be present in the skin.

The drug "Baneocin" has good tissue permeability. When applying the medicine to large areas of the body, the likelihood of systemic absorption of antibiotics must be taken into account.

Inactivation by tissue components, blood and biological products is not observed in the drug.

Indications for use

The external drug “Baneocin” for bruises (reviews about it will be discussed later) helps very well. In addition, it is used to treat infectious and inflammatory skin diseases that were caused by bacteria sensitive to the drug:

  • as a prevention of umbilical infection in newborns;
  • bacterial skin infections of limited prevalence (including infected eczema, weeping contagious impetigo, bacterial diaper dermatitis, infected trophic ulcers on the legs, secondary bacterial infection with herpes and chickenpox);
  • as a prophylaxis against infections after dermatological procedures or surgery (for example, after cauterization, tissue excision, episiotomy, as well as in the treatment of weeping wounds, sutures and cracks).

Contraindications for use

Now you know for what purposes Baneocin can be used. Reviews (skin rashes of an infectious nature are also indications for the use of this drug) from doctors indicate that this drug also has contraindications. These include the following conditions:

  • severe disturbances in the excretory function of the kidneys (due to renal or heart failure);
  • extensive lesions of the skin (there is a possibility of developing an ototoxic effect, which is accompanied by hearing loss);
  • hypersensitivity of a person to neomycin, bacitracin and other aminoglycosides;
  • pathologies of the cochleo-vestibular apparatus (there is a possibility of systemic absorption of the drug).

It should also be noted that it is strictly forbidden to use the drug to treat the eyes.

Doctors' recommendations for using the drug

Before using Baneocin powder or ointment, you should definitely consult your doctor. According to them, this drug must be applied locally to adults and children, that is, strictly to the infected area. If necessary, the medicine can be covered with a gauze bandage.

Treat the affected areas with ointment or powder 2-4 times a day. If burns are being treated, damage from which covers more than 15% of the entire body, then treatment with drugs is carried out once a day. This limitation is due to the likely absorption of the drug into the systemic circulation.

The maximum permissible dose of the drug is 1 g of active substance per day. This corresponds to 200 g of ointment or powder.

Treating a patient in excess of the specified dosages can lead to the absorption of large amounts of antibiotics into the blood, which can lead to toxic damage to the kidneys and ear. Therefore, during therapy with Baneocin, the patient’s condition should be regularly monitored by doing urine and blood tests, as well as a hearing test.

When treating large incisions and wounds, as well as infections of the ear canal (for example, otitis externa), the medicated ointment should be applied to the turundas, which subsequently need to be inserted into the ear cavity or wound.

When using the drug, you must ensure that it does not get into your eyes.

Long-term use of powder or ointment can lead to the development of fungal infections, which will require the prescription of additional drugs.

If, while using Baneocin, the patient develops an allergy or has any other infection, the drug must be discontinued.

Use in pediatrics

Reviews from pediatricians about Baneocin are positive. Doctors say that this drug is completely safe for children. The medicine in powder form can be used to treat the umbilical wound from the first day of the baby’s life.

According to expert reviews, the effectiveness of this product is very high. The umbilical wound heals within 2-5 days.

The powder is also actively used for treating native wounds and treating a festering or weeping umbilical stump.

How should Baneocin be used for streptoderma in children? Reviews from experts say that to treat such a disease, the affected area of ​​the skin is sprinkled with powder twice a day.

This form of the drug should be kept in your first aid kit, especially if you have small children.

According to pediatricians, this remedy is excellent for healing scratches, wounds, bites, cuts, calluses, as well as skinned elbows and knees. If the baby is burned, the damaged area of ​​skin should also be sprinkled with powder. This will significantly speed up his recovery.

Doctors say that Baneocin powder successfully replaces brilliant green, iodine and alcohol.

Infants often develop diaper dermatitis and prickly heat. These diseases are also perfectly treated with the medication in question. In this case, the powder is used as regular baby powder. As a rule, complete epithelization of scars occurs after 6-10 days.

Use of ointment in adults

Does Baneocin help with boils? Reviews from doctors say that this drug is quite effective in treating any purulent lesions. After treating the affected areas, the patient’s recovery occurs very quickly. As a result of this, there is no need to cut out the boil with a scalpel.

It should also be noted that Baneocin ointment helps against lichen. Reviews from dermatologists indicate that regular use of this drug contributes to a speedy recovery of the patient.

By the way, this medication is often used for diseases such as acne. "Baneocin" for acne (reviews about the drug are extremely positive) are used once a day, before bed.

Side effects

Does the drug Baneocin cause side effects? Reviews from doctors inform patients that this medication may cause unwanted effects. Let's look at them in more detail:

  • Allergic reactions. Long-term use of the drug often causes dry skin, redness, itching and skin rash. As a rule, allergies manifest themselves as contact eczema and are observed very rarely. In 50% of cases, such reactions are associated with taking other aminoglycosides.
  • Systemic side effects. When using the drug on extensive skin lesions, it is necessary to take into account the likelihood of its absorption, which may result in the development of oto- and nephrotoxic reactions, as well as neuromuscular conduction disorders.

Drug interactions

During systemic absorption of Baneocin, it is prohibited to use aminoglycoside antibiotics or cephalosporins, as there is a high probability of developing nephrotoxic reactions.

The combination of this drug with Furosemide or ethacrynic acid can cause oto- or nephrotoxic reactions.

During systemic absorption of Baneocin, it is not recommended to prescribe opioid analgesics, anesthetics and muscle relaxants, since in this case the risk of neuromuscular blockade increases.

Analogues of the drug

There are several drugs that have the same therapeutic effect as the drug Baneocin. Analogues of this product include the following ointments, solutions, aerosols and gels: “Bactroban”, “Gentamicin”, “Neomycin”, “Levomycetin”, “Lincomycin”, “Supirocin”, “Fuzimet”, “Levovinisol”, “Fuzidin”, "Fusiderm", "Sintomycin" and others.

Doctors' reviews about the drug

As mentioned above, doctors speak only positively about Baneocin powder and ointment. In their opinion, this is one of the few drugs that can cope with absolutely any disease, including an infectious one.

According to medical practice, the use of this product in recommended dosages allows you to get rid of bruises, boils, lichen, dermatitis and other undesirable conditions in the shortest possible time.

Many doctors are also pleased by the fact that the drug “Baneocin” is completely safe for small children, including newborns.

Source: http://www.syl.ru/article/211125/new_preparat-baneotsin-otzyivyi-vrachey