Isofra for kids

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Isofra for children: instructions for use

During the flu season and other acute respiratory viral infections, the entry point for pathogens is the upper respiratory tract. It is the mucous membrane of the nose and paranasal sinuses that viruses are the first to attack and often remain on it, causing inflammation.

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They are often accompanied by harmful bacteria, which cause purulent runny nose, sinusitis, otitis media and other diseases. In such situations, local antibiotic preparations, which include Isofra, are in demand. Is this medicine approved for children and how to use it correctly?

Release form

The medication is available in the form of a nasal spray with a concentration of the active ingredient of 1.25%. Inside one plastic bottle of Isofra there is 15 milliliters of clear liquid. The bottle has a screw cap made of polyethylene. It is sold in a cardboard box along with instructions and a spray nozzle.

Compound

The main component of the drug, responsible for its therapeutic effect, is represented by framycetin sulfate. Its dosage per 100 milliliters of solution is 800 thousand international units or 1.25 grams, that is, one milliliter of the drug contains 12.5 mg of framycetin. To keep the medicine liquid and not spoil, purified water, citric acid, sodium citrate, methylparaben and sodium chloride are added to it.

Operating principle

Framycetin in the spray is an antibiotic representing the group of aminoglycosides. It has a local bactericidal effect against both gram-positive flora and many gram-negative microorganisms.

  • Staphylococcus aureus;
  • Some strains of streptococci;
  • Pseudomonas aeruginosa;
  • E. coli;
  • Klebsiella;
  • Shigella;
  • Haemophilus influenzae;
  • Salmonella;
  • Enterobacter;
  • Proteus.

By damaging the cytoplasmic membranes in the cells of microorganisms, the medicine affects metabolic processes, which is why the pathogen quickly dies. However, Isofra does not affect some bacteria, for example, anaerobic microbes or pneumococci. Do not use the drug in case of viral infection of the nasopharynx, for example, with ARVI or influenza.

It should also be noted that those bacteria on which framycetin usually acts may also be insensitive to the drug. This is indicated by the lack of improvement after several days of treatment with the spray. If after 4-5 days from the start of using the product, the discharge does not decrease, and the nose is still stuffy, you should consult a doctor.

Indications

The drug Isofra is most in demand for infectious processes that are localized in the upper respiratory tract, since most pathogens of such pathologies are sensitive to framycetin.

  • For rhinitis, when harmful bacteria cause inflammation of the nasal mucosa, manifested by thick yellow-green discharge.
  • With rhinopharyngitis, when an inflammatory process in the pharynx is added to a runny nose of a bacterial nature.
  • For sinusitis, if pathogens enter the paranasal sinuses and provoke sinusitis, sphenoiditis, frontal sinusitis or ethmoiditis. Such pathologies are most often diagnosed in children under 15 years of age. The disease often develops as a complication of rhinitis, when in a small patient the symptoms of a runny nose first go away, and then the body temperature rises, and a thick purulent secretion begins to be released from the nose.

The spray is also prescribed by ENT doctors for prophylactic purposes after operations in the nasal area to prevent inflammation and bacterial infection in the postoperative period.

In addition, Isofra is used for adenoiditis, since clinical trials have shown that the use of this spray helps with nasal congestion, making breathing easier, and after a course of treatment for third-degree adenoids, many patients experience improvement (the degree decreases to second).

At what age is it allowed to take it?

According to the manufacturer's recommendation, Isofra spray should be used in children aged 1 year and older.

However, there are clinical studies showing that the medication is safe for children under one year of age. They confirmed the possibility of using the medicine in babies older than one month, but only a doctor should prescribe it to infants.

The spray form allows for uniform treatment of the nasal mucosa, and the active substance enters the blood of infants in such a small amount that it does not provoke any harmful effects. Therefore, you should not be alarmed that such young children are prescribed antibiotics into the nose. Using this medication in children, you can avoid the use of antibiotics orally, which is often accompanied by side effects, promotes allergization and disrupts the balance of the natural flora in the child’s body.

Contraindications

Isofra should not be used if you are intolerant not only to framycetin, but also to any other aminoglycoside antibiotic, for example, streptomycin or gentamicin. In addition, the medicine should not be used to rinse the paranasal sinuses. If a child with sinusitis has septal damage, treatment with Isofra is also not recommended.

Side effects

The body of some young patients reacts to the injection of Isofra with an allergy. If it appears, further use of the spray should be stopped. Other side effects do not appear during treatment with this drug, but the annotation for the medicine notes the likelihood of resistance to such an antibiotic in the microorganisms against which it is used. In this case, the drug must be replaced with another antibacterial agent, taking into account the sensitivity of the pathogen.

Instructions for use and dosage

  • Isofra is used only intranasally, and the drug must be injected rather than instilled, since the use of a spray will create the desired concentration of the drug and distribute the antibiotic evenly inside the nasal passages.
  • Before treating the nasal cavity with the medicine, it should be cleared of excess secretions and crusts. When administering the medication, the bottle should be held vertically, trying not to tilt it to the side.
  • In childhood, the drug is used three times a day, one injection into each nasal passage. In this case, the duration of treatment with the spray should not exceed one week.

Overdose

Since the Isofra solution applied to the mucous membrane acts only at the site of application, and it does not penetrate into the systemic bloodstream, there have been no cases of overdose of such a medication with a single injection of a large dose. If treatment with Isofra, even in the dosage prescribed by the doctor, continues for longer than 7-10 days, this threatens to disrupt the composition of the microflora of the nasopharynx (provokes dysbacteriosis).

Interaction with other drugs

Since the medicine is used topically, the manufacturer does not mention any incompatibility with other drugs. Isofra can be prescribed together with Rinofluimucil, Vibrocil and other medications that have anti-inflammatory, decongestant and vasoconstrictor effects. However, these drugs cannot be administered into the nasal cavity at the same time, so as not to reduce the antibacterial effect.

Terms of sale

Isofra, like many other antibacterial agents, is a prescription drug. Therefore, before you go to the pharmacy for such medicine, you should consult a doctor and get a prescription from him. The average price of one bottle of spray is rubles.

Storage

Since Isofra is available in light-proof packaging, there are no special requirements for storing the bottle. It is important that a small child does not have access to the place where the medicine will be placed. The manufacturer's recommended storage temperature is less than 25 degrees Celsius. The shelf life of the product is 3 years and is indicated on the packaging. If the marking has been erased or the end date has passed, it is unacceptable to spray the drug into the child’s nose.

Reviews

There are quite a lot of positive reviews about the use of Isofra spray in children. Doctors praise the drug for its wide range of effects on bacteria, rare cases of resistance to its active substance, and a convenient dosage form, thanks to which the antibiotic reaches the nasopharyngeal mucosa in a sufficiently high concentration. Another advantage of the drug is its exclusively local effect.

Mothers note that the medicine helps to cope with a long-term runny nose, the symptom of which is purulent, thick discharge. The effectiveness of the drug is confirmed for sinusitis and complications of a runny nose with otitis media.

An allergic reaction during treatment is very rare.

The price of the spray is considered affordable by many parents, so they rarely look for cheaper drugs. The disadvantage of the drug is its unpleasant taste, which children do not like. In addition, mothers note that the injection occurs with quite a lot of force, which causes them concern. Some mothers are afraid of side effects, because Isofra is an antibiotic, but the experience of many parents and doctors shows that children generally tolerate the medicine well, and the bacterial infection goes away quickly.

At the same time, doctors, including doctor Komarovsky, warn that giving children antibacterial drops without consulting a specialist is unacceptable.

If used incorrectly, the medicine will not have the desired effect and may even lead to addiction, which is why in the future you will have to use stronger drugs or use antibiotics systemically in the treatment of bacterial sinusitis or rhinitis.

Analogs

No other drugs based on framycetin are produced, so if it is necessary to replace Isofra, doctors prescribe drugs with a similar therapeutic effect, but with a different composition:

  • Protargol. These drops based on silver proteinate have an antiseptic and astringent effect, and also reduce the severity of inflammation during the runny nose, conjunctivitis, sinusitis, otitis media and other diseases. Children are prescribed medication from birth.
  • Dioxidine. This antimicrobial agent is produced in the form of a solution, which is sometimes recommended to be dripped for a runny nose or otitis media. In some cases, the doctor prescribes complex drops with this component.
  • Polydexa. The composition of this nasal spray includes two antibiotics of different groups, supplemented with phenylephrine and glucocorticoid. In children, this medication is used at the age of 2.5 years and older.

You will learn everything about childhood runny nose and its treatment from Dr. Komarovsky’s program in the next video.

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Source: http://www.o-krohe.ru/antibiotiki/izofra/

Isofra for children - instructions for use

Parents begin to encounter acute respiratory diseases in children quite early, so they should know what medications they need to have on hand. Isofra has proven itself well for children. This medication in the form of a spray contains antibiotics that can stop the proliferation of pathogenic microflora.

Despite the fact that the instructions for use of the product are quite accessible and detailed, it is strictly prohibited to prescribe the drug to children on their own. Even the local action of antibiotics can lead to the development of negative consequences for the child’s body.

Indications and contraindications for the use of the drug

Isofra can only be prescribed to children by a doctor after an examination and a series of studies. Most often, the following conditions are indications for therapy:

  • Inflammation of the nasal mucosa of various etiologies. The only thing is that the medicine is not recommended for use when exposed to an allergic component, because the main component of the composition affects only microorganisms of a bacterial nature.
  • Inflammation of the sinuses (one or several at once).
  • As part of complex therapy, Isofra for children is prescribed for sinusitis and otitis.
  • Inflammation of the mucous membrane of the nasopharynx, tonsils, adenoiditis of the second and third degrees. When the listed formations and tissues grow in the areas where they are located, this provokes not only unpleasant sensations for children of any age, but also negative consequences. So there is no point in delaying the complex impact.
  • The period after surgery to prevent the formation and spread of bacterial colonies.

Despite the fact that the instructions for use of the medication state that it can be used to treat children over 1.5 years old, only a doctor can decide whether therapy is appropriate in a particular case. Regardless of what age the little patient has reached, there are contraindications prohibiting the use of the drug.

These include intolerance to the components of the product, an allergic cause of the development of a runny nose (due to the inhibition of beneficial microflora, the child’s condition may even worsen). In addition, the instructions prohibit using the product to rinse the maxillary sinuses or carry out treatment for longer than 10 days. In the latter case, dysbacteriosis may develop, which will increase the risk of fungal diseases in the baby.

The mechanism of action of the product and features of its dosage form

The effectiveness of Isofra is due to the presence of framycetin in the drug. This is a substance that has an antibiotic effect, which is aimed at inhibiting the vital activity of many pathogenic microorganisms. They are capable of neutralizing both gram-positive and gram-negative bacteria.

Isofra is prescribed to children quite often, because... during the treatment process, it has only a local effect, without having a negative effect on organs and systems (of course, subject to the rules contained in the instructions for use of the medication). It turns out that after the end of therapy there is no need to additionally treat the baby for dysbiosis, as is the case with the use of conventional antibiotics.

Advice: Despite the fact that today you can increasingly see advertisements for Isofra drops on the Internet, you should not be tempted to try this product, even if the price is very attractive. At best, this is a marketing ploy, at worst, an attempt at fraud, which can be costly for a person of any age and seriously affect his health.

Isofra for children and adults is produced only as a spray for several reasons:

  1. The sprayed product is much better distributed over the affected surface and provides the maximum possible coverage even in those places that have many natural curvatures (orifices in adnexal cavities, lattice labyrinth).
  2. This type of drug administration guarantees the highest possible safety of treatment. If liquid is injected into the baby's nose, it may enter the pharynx and then drain into the digestive tract. In this case, there is a risk of overdose of the active substance and the development of side effects. The sprayed component simply cannot get into the baby's stomach, at least not in large quantities.
  3. Finally, the medicinal product in the form of tiny particles allows the main component to be dosed over the affected surface, which guarantees effective treatment and high-quality destruction of all pathogenic microflora.

Considering the fact that the price of the product is quite affordable, when treating and preventing the listed diseases in several family members, it is recommended that everyone purchase their own bottle. This will reduce the likelihood of infection spreading.

How to use Isofra in childhood?

Despite the fact that the instructions for using Isofra are quite simple, all aspects of its use must be additionally agreed with the pediatrician. In addition, you must adhere to the following rules:

  • The duration of treatment cannot exceed 10 days. If within 3 days from the start of therapy the child does not show positive dynamics, you need to inform the doctor about this. Most likely you will have to change your treatment tactics.
  • One dose of medication is injected into the child’s nasal passages at a time, i.e. do one spray. The manipulation is carried out up to 3 times a day, if the child is not yet 12 years old or the doctor has not established a different treatment schedule.
  • Before using Isofra, children need to clear the nasal passages of crusts and mucus. Only after this can the drug be used. In this case, you do not need to insert the tip into the nostril, but only apply it to it in order to then inject the medication.

In addition, you need to remember that you need to be very careful when combining the drug with other medications. For example, the product is not used simultaneously with antifungal agents.

Signs of overdose and side effects from treatment

If the instructions for use of Isofra are followed, then the risk of overdose is minimal. According to experts, such cases have not even been recorded. In situations where the baby accidentally injected himself with an impressive dose of the drug or even drank it, it is necessary to immediately call a doctor and monitor the child’s condition all the time before his arrival.

Additionally, it is recommended to solder it with liquid or even give it some kind of sorbent (for example, Enterosgel). In some cases, in response to the ingestion of a large amount of medication into the child’s body, manifestations characteristic of an allergic reaction are observed.

An allergy to Isofra can manifest itself as follows:

  • The appearance of a rash all over the body or hives.
  • Inhibition of the microflora of the nasal mucosa with the appearance of signs of dysbacteriosis.

If there is any negative response from the child’s body to the treatment, you must immediately notify the pediatrician and follow his further instructions.

Polydexa and Isofra – what to choose?

One of the conditional analogues of Isofra is the drug Polydex. True, these medications have one significant difference - Polydexa contains two antibiotics at once, which expands its therapeutic capabilities. Each of the active substances acts on its own group of microorganisms, which allows us to count on a more pronounced effect. In addition, Polydexa contains a component that narrows the lumen of the vessels of the nasal mucosa. Additionally, it is worth highlighting dexamethasone - it relieves inflammation and acts as an antihistamine. Thanks to the last component, Polydex can be used even for allergic rhinitis.

It turns out that Polydex can be called a more serious drug. Among other things, it is available not only in the form of a spray, but also drops, including ear drops (they do not have a vasoconstrictor effect). Given the great aggressiveness of Polydexa, it can only be used after the child turns 2.5 years old. There are a few more contraindications to such therapy: liver and kidney diseases, glaucoma, viral diseases, and the use of a number of medications.

Despite the proven safety of Isofra and the abundance of positive reviews from parents who have tried it in practice, it is strictly forbidden to prescribe it to a child on your own. It should not be used as a preventative measure unless indicated and permitted by a pediatrician. By injecting a sufficiently active drug, you can destroy the beneficial microflora of the nasal mucosa, which will lead to the development of a number of unpleasant and even dangerous conditions. After therapy, it is better to throw away the bottle with the product or, as a last resort, treat its tip. Otherwise, in the future there is a risk of infection joining the existing pathological process.

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Isofra for children

Every parent wants their child not to get sick, but, unfortunately, it is not possible to avoid colds. And when a problem arises, it needs to be solved. It is best to consult a doctor, who will prescribe treatment.

Very often our children develop a runny nose, this is an inflammation of the nasal mucosa. A child’s nose is always susceptible to the penetration of various bacteria, pathogenic microflora and viruses. With this disease, swelling of the nasal mucosa occurs, with the appearance of mucous or purulent mucous discharge. If the disease becomes severe, the use of medications is necessary. There are a series of such remedies for young children, and one of their representatives is isofra.

The medicine must be prescribed by a doctor after examining the child.

Isofra is used to treat the upper respiratory tract, these are:

  • rhinitis (inflammation of the nasal mucosa)
  • sinusitis (inflammation of one or more paranasal sinuses)
  • pharyngitis (inflammation of the pharyngeal mucosa).
  • postoperative periods (as treatment or prevention).

These diseases are caused by pathological microflora, and if treatment is not started in time, various complications are possible.

Drug Isofra

  1. Isofra for children contains the antibiotic framycetin, which is a broad-spectrum medicine. Has the ability to kill both gram-positive and gram-negative bacteria.

At what age can Isofra be given?

Caring parents always have a question: at what age can isofru be given? The nasal spray is prescribed to children from the age of one and a half years, but there are cases when it is also prescribed to children up to one year old. The results of the study and the use of this drug gave effective results. The drug is prescribed as a separate independent drug, or as part of a complex treatment of the disease.

Instructions for use

Like any other instruction, the instructions for isofra contain a description of the pharmacological action, indications, contraindications, and interactions with other drugs. What complications can arise from an overdose of isfora? When purchasing any medicine, you must read the instructions, even if the medicine was prescribed by a doctor.

Isofra for children is available in spray form. It has many advantages over nasal drops. The product is equipped with a special dispenser, with the help of which the medicinal substance is sprayed. The dispenser sprays such small particles that it is possible to penetrate the medicinal solution even into the most inaccessible places of the nasopharynx. The dispenser is capable of dispensing the required portion of liquid at once. It is very convenient for both children and adults.

Compared to nasal drops, when instilled, some of the drops may flow back, and some may enter the throat, and have less effect on the bacteria located on the nasal mucosa.

The spraying effect of isofra always acts where it is needed and with a certain dosage, one spray corresponds to one dose. Thus obtaining the desired therapeutic effect, this nasal spray has already gained an excellent reputation among medical professionals and their patients.

When isofra is prescribed to children, it is necessary to undergo tests to determine the tolerability of the drug and the sensitivity of this antibiotic to the bacterial microflora present in the respiratory tract. And if the test results do not give any contraindications, then Isofra for children can be safely used and get the desired effect.

You should not use the drug for allergic rhinitis; there will be no result even if the bacteria have a strain resistant to framycetin. Use Isofra only as prescribed by a doctor.

It will be of great benefit to study the instructions for use of Isofra, which contains information that if the effect of using the drug does not occur within three days, you must inform your doctor about this. And choose another drug.

The drug isofra for children is designed for a short time of use, like any other antibiotic. One bottle is enough to treat, the price of the product is affordable, although when it comes to a sick child, the question of cost comes last.

When treating sinusitis and other complicated diseases in children, isofra alone will not be enough; the doctor must select a comprehensive treatment with medications in combination with physiotherapy, and then the effectiveness of isofra spray will increase significantly. But it is strictly forbidden to combine isofra with antifungal drugs, as the therapeutic effect is reduced.

Indications for the use of the drug are the following diseases: infectious rhinitis of bacteriological etiology, chronic non-allergic rhinitis, sinusitis, sinusitis and the postoperative period during operations in the nasal cavity.

Contraindications

  1. Contraindications for use are individual intolerance to the components of the product.
  2. It is not advisable to prescribe isofra to patients prone to allergic reactions.
  3. Isofra is also contraindicated during pregnancy and breastfeeding.
  4. The instructions confirm that this drug cannot be used to rinse the paranasal sinuses.

How to use Isofra

Isofra is usually prescribed to children; it should be used for no more than ten days, during which time a therapeutic effect should occur; if the drug is used for a long time, it is possible to destroy the beneficial microflora of the nasopharyngeal mucosa.

Children need to spray the spray three times a day in each nasal passage, one dose. Before treatment, you need to clean the child's nose. Place the bottle near the nasal passage and make one injection. Sometimes in some children the drug causes local irritation, redness near the nose, rash or itching, in which case you should stop using the spray. And be sure to inform your doctor about any problems that arise.

Only a doctor can determine at what age isofra can be given; in general, it is intended for children after one and a half years. But there are cases when the doctor decides to prescribe the drug to children in the first months of life. And pregnant women are prescribed the drug for severe cases of the disease, since the likelihood of the antibiotic penetrating into the blood is very low, and a runny nose can be cured within a few days. Clinical trials have shown the effectiveness of treatment for children under one year of age and pregnant women. But the drug is still prescribed only in extreme cases.

And I would like to remind you once again that self-medication is dangerous, especially if the problem concerns a child. In any case, you must seek help from a specialist and use the drug under the supervision of a doctor.

Isofra for children: reviews

But isofra didn’t help us, we took it for 7 days, no effect

My little one had acute sinusitis, we already thought we would have to take antibiotics, but everything went away thanks to the fact that Isofra started dripping, even the temperature dropped. In short, good drops, I now recommend them to everyone, for all sorts of severe types of runny nose.

Our ears hurt all the time, it turned out to be all from our nose. The doctor prescribed isofra drops, and already on the second day it was clear that the baby was feeling better. In short, our ears no longer bothered us; two years have passed.

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"Isofra": instructions for use of nasal spray for infants and children over one year old

The nasal mucosa in children has little protection against bacteria. Therefore, a runny nose is a very common complaint among children. The drug Isofra is a remedy that works against inflammation of the nasal mucosa. A local antibiotic that suppresses the proliferation of pathogenic organisms and combats nasal congestion. It is used to treat a runny nose of a bacterial nature and its complications.

Release form, composition and effect of the drug

Many people incorrectly call this drug drops. In a laboratory in France, pharmacists developed a spray, and it is now being successfully produced. Thus, there is only one form - a spray containing 15 ml of framecithin sulfate and excipients. Isofra drops do not exist.

The main component of the drug is framycetin. This is a strong aminoglycoside antibiotic. It is very effective in the fight against a huge number of bacteria - streptococcus, pseudomonas, enterobacteria, etc. Pseudomonas aeruginosa, enterococci, streptococci, some staphylococci, chlamydia, rickettsia and mycoplasma are resistant to it. The spray has the following composition:

  • sodium chloride;
  • methyl parahydroxybenzoate;
  • water;
  • sodium citrate;
  • citric acid monohydrate;
  • E218.
The substance acts destructively for bacteria, preventing microorganisms from conducting normal life activities.

Indications for use of the spray

Use the product in accordance with the instructions if the problem is bacterial:

  • with purulent sinusitis;
  • with prolonged nasopharyngitis;
  • with adenoiditis;
  • for acute rhinitis and sinusitis;
  • after surgical interventions.

Be careful if you have a deviated nasal septum or rhinitis caused by allergies.

Can Isofra be used for children under one year old?

The question of at what age or month can children start using the solution is quite controversial. Although the annotation states that the drug is not prescribed to children under one year of age, clinical experience indicates the possibility of its use for the treatment of infants. Many otolaryngologists use it during treatment, because it is a good replacement for many systemically acting antibiotics.

Sometimes doctors prescribe Isofra to very young patients, due to the high effectiveness of the drug in the treatment of bacterial infections

Based on the results of experiments, it was found that the product is characterized by high effectiveness and good tolerability in infants. When treating infants with sinusitis or a runny nose with Isofra, most children recovered in less than 7 days, and when using other antibacterial substances, treatment took about 10 days.

Something to remember! At this age, the nasal passages are short. Spraying may cause otitis media or eustacheitis in young children.

Instructions for use of the drug

The instructions for the drug are provided for informational purposes only; all decisions regarding use are made by the doctor. The spray bottle must be in an upright position when administered. The dispenser must be inserted first into one nasal passage and make one injection, then into the other.

Before using the spray, you must read the rules set out in the annotation:

  • It is imperative to maintain equal time intervals between injections of Isofra for children.
  • One spray is permissible at a time, otherwise the dose of the antibiotic increases and there is a high probability of side effects.

The drops must be used strictly according to the instructions, since they are not suitable for treating any runny nose.

How to drip Isofra?

How to use the spray correctly is indicated in the instructions:

  1. if there is congestion, you first need to empty your nose - a minute before the procedure you need to drip vasoconstrictor drops (we recommend reading: Sialor drops for children);
  2. to determine the dosage, you need to spray the product several times to the side;
  3. bend your head forward and spray one spray into each nostril;

How often and for how many days can the product be used?

The children's dosage is one spray into each nasal passage three times a day. The course of treatment is 7-8 days. The maximum duration of the course is up to 10 days, but if the baby does not get better within a week, then the medicine must be discontinued.

By following the instructions, the risk of overdose is minimized. If a child accidentally injects himself with a large dose of the spray or even drinks it, you need to call a doctor and monitor the baby’s well-being. It is also necessary to give him as much liquid as possible and give him a sorbent. Allergy may occur. Due to the low absorption rate, an overdose is practically impossible.

Contraindications and possible side effects

Manufacturers prohibit the use of the medicine in the following cases:

  • in case of individual intolerance to components;
  • in the presence of an allergic reaction;
  • during pregnancy and breastfeeding;
  • as a nasal rinse.

Remember that Isofra should not be used with antifungal medications, because they can neutralize the effect of the spray. Please note the following restrictions:

  • high sensitivity of the child’s body to the active substance or additional components;
  • child is less than 12 months old.

In general, the drug is well tolerated, although there have been cases of allergies. In case of an allergic reaction, use should be stopped, the nose should be rinsed carefully, and the throat should be rinsed thoroughly. If the doctor considers it necessary, take antihistamines.

With long-term treatment, the drug dries out the nasal mucosa, changing its microflora. Long-term use is addictive. If you have any negative reaction to treatment, you must inform your doctor.

Analogues of Isofra spray

At this time, there are no drugs with an identical active antibiotic. There are similar drugs containing aminoglycosides.

For the drug Isofra, you can select products that are similar in the effect obtained. It is usually suggested to replace the drug Isofra with the following medications: Collargol, Polydexa, Protargol, Rinofluimucil, Chlorophyllipt and many others. The composition of these drugs includes: garamicin, dilaterol, bramitob, streptomycin, amikacin and a number of other substances.

It is difficult to consider these drugs as analogues, because Rinofluimucil, for example, does not replicate either the composition of Isofra or the mechanism of action. It can only be called an analogue as a cure for a runny nose. The drug is prescribed for various rhinitis, which significantly distinguishes it from Isofra.

It is often recommended to replace Isofra with Polydex. This is extremely wrong and harmful. Polydexa contains two other antibiotics plus a hormone. The product is stronger and more effective. Allowed to be used only from 2.5 years.

Previously, the drug Bioparox was often prescribed. It has an extended antimicrobial effect. However, Bioparox is currently prohibited from production.

The doctor decides which remedy is best. You can study various analogues and, with the consent of the doctor, replace the medicine with one that is cheaper. Below is a table for comparison with some analogues.

The possibility of using Isofra for infants remains controversial; there is no publicly available evidence for this, and the instructions indicate that it cannot be used. And the spray, as far as I know, cannot be used at all for small children.

I think that in any case, consultation with a competent pediatrician is necessary. One must be very careful when treating infants, especially in the case of antibiotics. And sprays are indeed contraindicated for small children.

Attention! All information on the site is provided for informational purposes only and is for informational purposes only. For all questions regarding the diagnosis and treatment of diseases, you must consult a doctor for an in-person consultation.

Source: http://vseprorebenka.ru/zdorove/preparaty/izofra-dlya-detej.html

Isofra for children: instructions for use, price, reviews, analogues. Spray, drops Isofra in the nose for children

Nasal spray based on a component that exhibits bactericidal activity. Used for the treatment of rhinitis and sinusitis of infectious etiology. Can be prescribed to children from 1 year of age. Not suitable for long-term use. The therapeutic effect becomes noticeable the next day. If the patient’s well-being has not changed within a week, treatment is canceled. Belongs to the prescription group.

Dosage form

Isofra solution is available in opaque plastic bottles of 15 ml. The container is equipped with a special tip so that the solution can be sprayed like a spray.

Description and composition

The spray is colorless and odorless.

It is based on a broad-spectrum antibiotic – framycetin sulfate. 1 ml contains 8000 IU, which corresponds to 12.5 mg.

Additional substances included in the drug: methyl parahydroxybenzoate, sodium citrate, citric acid monohydrate, saline sodium chloride solution and purified water.

Pharmacological group

The drug belongs to antibacterial drugs, a group of aminoglycosides.

Mechanism of action

Framycetin acts on the ability of bacterial ribosomes to synthesize protein. Thanks to this, the effect of the drug is bactericidal (completely destroys foreign cells).

The spectrum of activity of the drug is wide - it affects the family of enetrobacteria (Escherichia, Proteus, Klebsiella), some gram-negative bacilli, some staphylococci and streptococci.

Indications for use

Isofra is indicated for the treatment of:

  • Rinitov
  • Sinusitis (acute and chronic)
  • Rhinosinusitis
  • Rhinopharyngitis
  • Postoperative conditions

When treating rhinitis, it is imperative to find out the cause of its occurrence. In case of allergic etiology of runny nose, the drug will not have an effect.

Catarrhal phenomena in acute respiratory diseases do not require treatment with an antibacterial spray.

Only rhinitis that acquires signs of bacterial can be successfully treated with Isofra. This should be a prolonged runny nose, difficult to treat with simple vasoconstrictor drops. The mucous discharge from the nose acquires a yellow or greenish tint.

For sinusitis (especially sinusitis), the drug has proven itself to be an effective remedy. But a good effect is possible only with complex therapy, with the prescription of not only a local antibiotic. In acute sinusitis (exacerbation of chronic sinusitis), it is more effective to use a systemic antibiotic together with framycetin in the form of an aerosol.

In the postoperative period, antibacterial therapy is always used to prevent bacterial complications. If using a nasal spray is sufficient, then Isofra is an excellent option.

Contraindications

The drug is contraindicated in people with intolerance to the main active substance or components. Also, you should not take it if you have a known allergy to drugs from the aminoglycoside group.

Isofra is contraindicated for rinsing the paranasal sinuses.

Isofra is not recommended for children under 1 year of age.

Use during pregnancy and lactation

The use of aminoglycoside drugs is contraindicated during pregnancy and breastfeeding. The fact is that an antibiotic of this group can negatively affect the fetus. The organ of the inner ear is susceptible to the negative effects of this group of drugs.

In a newborn child, the processes of formation of the vestibulo-cochlear system continue. Therefore, during breastfeeding this drug is prohibited.

Despite the fact that Isofra is a topical drug and its concentration in the blood is very low, the drug is contraindicated in pregnant women, breastfeeding women and infants.

Directions for use and doses

The drug is in a special bottle with a spray. It must be kept upright when in use. The tip is brought to the nasal entrance and 1-2 presses are made. In this case, the medicine is sprayed in the form of a spray.

If the bottle is turned over and pressed, the amount of medicine entering the nasal cavity increases. This is undesirable, especially in children.

When sprayed onto the mucous membrane of the nasal cavity as an aerosol, the drug does not cause discomfort and is evenly distributed over the surface. And most importantly, the effect of the drug begins faster. Thus, the desired effect occurs in a shorter time.

  • For children from 1 year to 5 years – 1 injection into each nasal passage, 3 times a day.
  • For children 6-12 years old, the drug can be used 3-4 times a day, also 1 injection.
  • Children over 12 years of age and adults can increase the frequency up to 5-6 times, 1-2 injections.

Despite the fact that the inflammation is predominantly localized on one side (difficulty breathing through one nasal passage), both nasal passages need to be irrigated with the medicine. This is a prerequisite for localizing the process and preventing complications of the disease.

The duration of use is usually from 5 to 7 days.

If there is no effect after 3-4 days, you should consult a doctor to adjust the treatment.

Side effects

Like any antibacterial drug, Isofra should be used for several days. If used incorrectly, most often when the treatment period is shortened, colonies of resistant microorganisms develop.

With excessively long-term use in persons with weakened immune systems, fungal infections may develop. Therefore, after 5 days of using the drug, be sure to consult a doctor.

Cases of allergic reactions have been described. There may be individual intolerance to the drug Isofra. As well as cross-allergy with drugs from the aminoglycoside group.

Therefore, the first application should be in the first half of the day to observe the body’s reaction.

Interaction with other drugs

No cases of interaction with other drugs have been recorded.

The drug is often used as one of the components of complex therapy.

special instructions

In case of recorded cases of allergy to a group of aminoglycoside antibiotics, the drug is not recommended for use.

Overdose

When this drug is used correctly (in aerosol form), cases of overdose have not been described.

If a child unintentionally ingests medication, seek immediate medical attention.

Storage conditions

Store out of the reach of children at a temperature not exceeding +25 o C.

Conditions for dispensing from pharmacies

Dispensed with a doctor's prescription.

Best before date

Each package is individually marked. Do not use after expiration date.

Analogs

  • Framinazine
  • Gentamicin
  • Kanamycin
  • Tobramycin

All these drugs belong to the same group of antibacterial agents. Framinazine, like Isofra, is a spray. Other medications are available in the form of drops.

Drug price

The cost of Isofra is on average 302 rubles. Prices range from 267 to 390 rubles.

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1 COMMENT

My son was prescribed this spray for a bacterial runny nose, as part of a complex treatment. After a week of use, the child recovered. In my opinion, the product is effective. But the sprayer is not very convenient.

Source: http://zdorrov.com/instruktsii-po-primeneniyu/izofra-dlya-detej.html

Isofra spray - fighting a bacterial nasal infection in a child

A child's runny nose is unpleasant: the baby's nose is stuffy, it is difficult for him to breathe, and mucous or purulent discharge irritates delicate skin. Isofra is a popular topical drug for the treatment of nasal infections. In what cases do doctors prescribe it, how to use this drug correctly, and why should it be used with caution? You will find answers to these questions in our review.

Isofra is a topical antibiotic.

How does the medicine work?

Isofra is a medicine with a pronounced antimicrobial effect. It contains the active ingredient framycetin with a dosage of 12.5 mg/ml - a local broad-spectrum antibiotic from the group of aminoglycosides (substances were first obtained from the radiant fungi Actinomyces, and are now used in medicine).

Aminoglycoside drugs block protein synthesis in bacterial cells, thereby destroying their active forms capable of reproducing.

Due to this, Isofra has the following pharmaceutical properties:

  • Antimicrobial - the drug reduces the total number of harmful bacteria in the nasopharynx.
  • Bactericidal - the medicine destroys the cell wall of microbes and fights them quickly and effectively.

If the disease becomes severe, an antibiotic is needed.

Benefits of using Isofra for nasal infections:

  • The effectiveness of a medicinal formula that allows you to quickly reduce the number of bacteria in the inflammation site. Unlike penicillins and cephalosporins, aminoglycoside antibiotics are not used as often, and the number of bacterial strains resistant to them is much smaller.
  • Wide spectrum of action - the medicine is active against both gram-positive and gram-negative pathogens of nasopharyngeal infections.
  • Thanks to the convenient form of release of the drug (in the form of a nasal spray), a high concentration of the drug is created at the site of infection - the tissues of the nasal mucosa and paranasal sinuses.
  • No systemic effect: the antibiotic acts only in the nasal cavity, is practically not absorbed into the blood and does not cause adverse reactions from internal organs.

Indications for prescribing the drug

Isofra is prescribed only for bacterial rhinitis. If the mucus in the child’s nose appears due to a virus, the medicine will not help (since antibiotics do not act on viruses).

Only a doctor can prescribe the drug.

Before using the product, consultation with a specialist is necessary, but you can assume the development of a microbial infection in your baby yourself. The main differences between the viral origin of snot and the bacterial origin are presented in the table.

The drug is indicated for:

Release form

Isofra is produced by the French pharmaceutical company Laboratoires Bouchara-Recordati.

The only form of release is a nasal spray. Pharmacies often ask for “Isofra drops.” Indeed, if you turn the bottle over and press on it, you can drip the product. However, this is incorrect; it is recommended to spray (holding the bottle vertically, with the tip up), and not to drip the medicine into the nose. When sprayed, it is distributed more evenly and creates an optimal concentration of the antibiotic on the nasal mucosa.

Isofra is sold in a bright pink box in a plastic bottle with a special spray nozzle and instructions for use.

The average price for a 15 ml bottle is 270 rubles.

Mode of application

The instructions recommend the use of the drug for the treatment of children over one year of age. Download instructions for use.

However, as a result of recent studies, the safety and good tolerability of the drug in infants older than one month have been proven. Therefore, in practice, pediatricians prescribe Isofra even to infants.

The spray is suitable for babies older than one month.

When using the medicine, follow these rules:

  • Before the procedure, ask your child to blow his nose or clean his nose with a cotton swab and saline solution.
  • Ask your baby to tilt his head forward a little or do it yourself. If he is not yet three months old and does not hold his head well, treat his nose by laying him on a flat surface on his back and slightly turning his head to the side so that the medicine does not flow into the larynx.
  • Hold the spray bottle vertically.
  • Insert the tip of the spray into the nasal passage and lightly squeeze the walls of the bottle - the medicine will be evenly distributed on the inflamed mucous membrane.
  • Repeat the same with the other nostril.

Remember that you cannot rinse your nose with this drug.

The course of treatment with Isofra for children is 10 days. Usually during this time the infection completely recedes. Improvements are noticeable within 4-5 days. Continuing treatment longer than the specified period, as well as quitting it without completing the course, is not recommended. In the first case, disturbances of the normal microflora (dysbacteriosis of the nasopharynx) are possible; in the second case, the infection may re-develop.

Isofra is practically not used for the prevention of rhinitis. In exceptional cases, a specialist may prescribe a course of treatment with the drug after surgery on the nasopharynx to prevent a hospital infection - any disease of microbial origin that the child contracted within the walls of the hospital. As a rule, it is severe and cannot be treated due to the resistance of “hospital” bacteria to most common antibiotics.

The drug is prescribed to children for whom ordinary nasal drops have not helped get rid of a runny nose.

Contraindications and unwanted effects

The only contraindication to the use of the drug is individual intolerance to its components. Isofra is usually well tolerated and rarely causes side effects. In medicine, isolated cases of general and local allergic reactions are mentioned: skin rash, itching, redness and swelling of the nasal mucosa, urticaria.

Drug interactions

Since Isofra spray acts only in the nasal cavity and is practically not absorbed into the blood, it can be used in combination with any other drugs to treat colds in a child. But at the same time, the combined use of other nasal drops (vasoconstrictor, hormonal, others for the common cold) can lead to a decrease in the medicinal effect of the antibiotic.

Analogues of Isofra

The only domestic analogue of the drug is Framycetin. Its composition is completely identical to Isofra. The price of Framycetin is 2-2.5 times lower, but finding it on pharmacy shelves is not so easy.

Several drugs that do not contain an antibiotic have a similar effect for nasopharyngeal infections:

  1. Protargol (or its analog Sialor) is a product based on silver molecules. Despite its different composition from Isofra, Protargol also has antiseptic and antimicrobial properties. It does not contain antibiotics, is produced in prescription departments of pharmacies, has a short shelf life and is used to treat bacterial rhinitis in children over 5 years of age.
  2. Rinofluimucil is a combined anti-inflammatory, anti-edematous, mucus-relieving medicine for the treatment of runny nose in children over 1 year of age. Also available in spray form.

Isofra's analogue is Rinofluimucil.

Many people call the drug Polydex the main analogue of Isofra, but this is not entirely true. Polydexa is a combination product based on two antibiotics (polymyxin B and neomycin). Each of them has its own spectrum of action and is active against its own group of pathogens. In addition, the medicine contains vasoconstrictor and hormonal components. Polydexa quickly and effectively copes with the cause and symptoms of rhinitis, sinusitis, pharyngitis, but has side effects and is not used to treat children under 3 years of age.

The previously popular local antibacterial and anti-inflammatory drug Bioparox is not recommended for the treatment of runny nose in children. The pharmaceutical company Servier Laboratories has reported several deaths associated with severe allergic reactions to its components, and the drug is likely to be discontinued.

Reviews

Inna (daughter of Alexander, 8 years old):

“The doctor advised the child to buy the drug Isofra when he saw how thick and green the snot was when we came to the appointment. He also recommended that before use, rinse your nose well with salt water (1 teaspoon of table salt per glass of water) or saline solution, which is not inferior to expensive products based on sea salt.

That's what we did. Although Sasha did not really like the procedure, we used the medicine three times a day for 10 days. Improvements became noticeable after 3-4 days: there was much less snot. Therefore, I have only positive reviews about this drug.”

Before using the spray, rinse your nose with salt water and ask your child to blow his nose.

Valentina (son Egor, 5 years old):

“My son has adenoids, so he gets sick very often. Last year, the doctor prescribed Isofra drops for us, and today this is the best remedy that helps us fight bacterial rhinitis.

The medicine copes with microbes quickly. I have to use it 4-5 times a year, and it did not cause addiction or allergies. The only disadvantages can be called the high cost and unpleasant sensations when injecting: the liquid flowing down the throat has a specific “medicinal” taste - my son doesn’t really like it.”

Kim P. S., pediatrician:

“Isofra has a clearly defined range of indications that must be followed. For viral and allergic rhinitis, the remedy can be not only useless, but also harmful to health. Dear parents! Use this antibacterial product only after a doctor’s prescription.”

Isofra nasal spray quickly and effectively copes with a runny nose and rarely causes side effects in childhood. This is confirmed by positive reviews from doctors and patients. But its use must be justified by the bacterial nature of the disease and recommended by a doctor. Only in this case will the treatment be beneficial. Speedy recovery to your baby!

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Source: http://www.o-my-baby.ru/zdorovie/lekarstva/ot-nasmorka/isofra.htm