Isofra analogues for children

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Isofra - instructions for use, reviews, analogs and release forms (nasal spray 1.25% nasal drops) of a medicinal product for the treatment of sinusitis in adults, children and pregnancy based on the antibiotic Framycetin

In this article you can read the instructions for using the drug Isofra.

Table of contents:

Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Isofra in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Isofra in the presence of existing structural analogues. Use of a drug based on the antibiotic Framycetin for the treatment of sinusitis and rhinitis in adults, children, as well as during pregnancy and breastfeeding.

Isofra is an antibiotic from the group of aminoglycosides for topical use in otorhinolaryngology. Acts bactericidal. Active against gram-positive and gram-negative bacteria that cause the development of infectious processes in the upper respiratory tract.

Framycetin sulfate + excipients.

Pharmacokinetic studies of Isofra have not been conducted due to low systemic absorption.

As part of combination therapy for infectious and inflammatory diseases of the upper respiratory tract, including:

  • rhinitis;
  • rhinopharyngitis;
  • sinusitis (in the absence of damage to the septum);
  • prevention and treatment of inflammatory processes after surgical interventions.

Nasal spray 1.25% (sometimes mistakenly called nasal drops).

Instructions for use and dosage regimen

Adults are prescribed 1 injection into each nostril 4-6 times a day.

Children are prescribed 1 injection into each nostril 3 times a day.

The average duration of therapy is 7 days.

When used, the bottle should be kept in an upright position.

  • allergic reactions (skin manifestations).
  • hypersensitivity to framycetin and other antibiotics from the aminoglycoside group.

Use during pregnancy and breastfeeding

Adequate and strictly controlled clinical studies of the safety of the use of Isofra during pregnancy and lactation (breastfeeding) have not been conducted.

If within 7 days of treatment the therapeutic effect is absent or weak, the drug must be discontinued.

No clinically significant interactions of Isofra with other drugs have been identified.

Analogues of the drug Isofra

The drug Isofra has no structural analogues for the active substance.

Analogs by pharmacological group (Aminoglycosides):

Source: http://instrukciya-otzyvy.ru/274-izofra-po-primeneniyu-analogi-sprey-nazalnyy-kapli-v-nos-gaymorit-framicetin.html

Isofra - instructions for use for children and adults + analogues + recipe in Latin + reviews

French drops (spray) in the nose Isofra is one of the most popular remedies for the treatment of a runny nose. It also effectively helps with sinusitis and rhinopharyngitis of bacterial origin, relieving characteristic symptoms already on the third day of use. Pediatricians especially often prescribe the drug, since the spray is safe and approved for use in children starting from the second year of life. The medicine has a minimum of contraindications and does not have systemic side effects on the body.

Isofra - instructions for use for children and adults

Positive reviews of the drug from adult patients and parents of babies to whom the spray was prescribed by a pediatrician indicate its undoubted effectiveness. Painful symptoms pass quite quickly, nasal congestion disappears, and complete recovery occurs in record time. In this regard, a logical question often arises: Is Isofra an antibiotic or not, and does it harm the body, like most antimicrobial drugs?

Yes, Isofra is an aminoglycoside antibiotic, a derivative of one of the first generation representatives of this group (neomycin). It is intended exclusively for local use in otolaryngological practice, and in combinations it is also used in ophthalmology and proctology. Therefore, treatment with this nasal spray, especially for children, requires a responsible approach and prior consultation with a doctor.

Pharmacological group

It belongs to aminoglycosides, since the active substance of the drug framycetin is a structural component of the first generation antibiotic of this group. ABP is intended only for local use in otolaryngology.

Composition of Isofra

The active ingredient of the nasal spray is the bactericidal agent framycetin, a derivative of the aminoglycoside antibiotic neomycin. It has a detrimental effect on pathogens due to damage to the cell membrane and disruption of metabolic processes inside the cell. The following pathogens exhibit sensitivity to the drug:

  • some gram-positive species of streptococci and penicillin-resistant staphylococci;
  • gram-negative pathogens of ENT infections - Klebsiella, Shigella, Pseudomonas aeruginosa, Salmonella and Proteus spp.

Anaerobes, certain strains of streptococci and treponema are immune to framycetin. In general, resistance to this antibiotic in pathogens develops quite slowly.

Release form

The medicine Isofra for the runny nose and some other infections of the ENT organs is available in the form of a spray. The manufacturer, the French pharmaceutical company Laboratoires Bouchara-Recordati, offers the medicine in 15 ml plastic bottles with a spray dispenser, additionally packaged in cardboard boxes.

Isofra nasal spray

The drug contains the active ingredient framycetin in an amount of 12.5 mg per milliliter, as well as auxiliary components: distilled water, citric acid, sodium chloride and citrate, methylparaben. The average cost of one package in pharmacies is 300 rubles.

Since most remedies for the common cold have the property of constricting blood vessels, thus reducing mucus production and preventing congestion, the question often arises:

As can be seen from the ingredient composition, there are no vasoconstrictors (compounds such as naphthysine that affect vascular tone) in the drug. Therefore, it does not have a vasoconstrictor effect, but is intended to combat exclusively the cause of the disease - infection.

Recipe in Latin

If Isofra spray is indicated for sinusitis, rhinitis or other ENT infections, the medical prescription must be properly documented on a special prescription form. Without this document, pharmacists and pharmacists from the beginning of 2017 do not have the right to dispense medicines according to the new rules. The prescription must contain some information about the patient, and also be certified by the seal and signature of a specialist.

Rp.:Spray"Isofra" 15 ml

DS One injection into each nasal passage three times a day.

Indications for use Isofra

Colds, usually of a viral nature, are often complicated by the addition of a bacterial infection. Such situations are especially typical for children, whose anatomy of the respiratory system facilitates infection by pathogenic microorganisms. Pediatricians prescribe a French-made spray for purulent green snot, the cause of which is:

  • acute runny nose of bacterial origin (nasopharyngitis);
  • chronic rhinitis;
  • inflammation of the paranasal sinuses (sinusitis), if there is no curvature of the nasal septum.

The nasal remedy Isofra for sinusitis, acute or chronic runny nose is widely used in adults. There is no special, more concentrated form of release; the medicine is simply sprayed into the nose more often than in the case of treating small patients.

Contraindications

Like any drug, this medication is strictly contraindicated in case of individual intolerance to its components: framycetin or aminoglycosides in general, auxiliary ingredients. It is also not recommended to use Isofra nasal spray during pregnancy from the 1st to 3rd trimester (that is, at any stage) and during breastfeeding.

Dosage

The medicine acts locally, on the surface of the mucous membranes of the respiratory organs, without penetrating into the bloodstream and, accordingly, without having a systemic effect. That is why this antibiotic can be used in pediatrics without fear of harmful effects on the child’s body. For the same reason, there have been no cases of overdose, as well as interactions with drugs taken orally or parenterally.

For children

Isofra is usually prescribed to a child with thick green snot, the appearance of which indicates the addition of a bacterial infection. In this case, before each use, it is recommended to first rinse the stuffy nose with special ready-made saline solutions sold in pharmacies or with regular saline solution. This procedure helps cleanse the mucous membranes and enhances the therapeutic effect of antibiotic therapy.

Holding the spray bottle strictly vertically, you need to perform one injection into each of the nasal passages. This is done three times a day (no more often) for several days, but no more than a week. Usually, the symptoms of the disease weaken or disappear completely on the third day of treatment, but if after 7 days the disease does not go away, you should stop using the drug and consult a doctor about changing the drug.

For adults

General recommendations for use are almost the same as for children. It is also advisable to rinse the nasal passages before administering the medicine, then make one injection into each of them. The maximum duration of a course of antibiotic therapy is 7 days. The only difference is the frequency of application: adult patients need to do this from 4 to 6 times a day.

Side effects of Isofra

When applied topically, the active substance does not enter the bloodstream, therefore it does not have a systemic effect on the body and does not cause dyspeptic disorders, dysbacteriosis, disorders of nervous activity and other negative reactions characteristic of antibiotic therapy. The side effect of this nasal spray can manifest itself (in very rare cases) only in the form of a local allergy - burning or redness.

Isofra during pregnancy and breastfeeding

There is no reliable data on the effect of framycetin on the fetus and the degree of penetration into breast milk, since large-scale clinical studies have not been conducted. If we take into account the inability of the antibiotic to penetrate the blood, we can conclude that it is safe, however, the manufacturer in the instructions for use prohibits prescribing the drug to pregnant women at any stage and lactating women.

Isofra and alcoholic drinks

Antimicrobial drugs for topical use do not mix with ethanol entering the blood. From this one can draw an erroneous conclusion about the compatibility of nasal spray and alcohol. However, alcoholic drinks dilate blood vessels, causing a rush of blood to the tissues, as a result of which the formation of mucus increases, swelling increases, and the condition generally worsens. In addition, alcohol in any case has a negative effect on the body weakened by the disease.

Isofra - analogues are cheaper

The cost of the medicine from the French manufacturer is quite high (at least 300 rubles for one bottle), but the packaging is enough for the full course of treatment. If, however, there is a need to replace the medication, you need to consult a doctor, since there are no structural analogues of the framycetin-based spray. Usually in this case, antiseptics suitable for the treatment of adults and children are recommended:

  • Protargol is a 2% solution that is prepared in a pharmacy and costs about 100 rubles. True, pharmacists often offer a ready-made analogue called Siarol, which is not inferior in price to Isofra.
  • Oil solution Chlorophyllipt, which helps to cope with a runny nose in combination with systemic medications - 20 ml costs approximately 140 rubles.
  • Miramistin is an antiseptic spray, 50 ml of which will cost 200 rubles.
  • Collargol is an antiseptic drug with bactericidal action, which is prepared directly in the pharmacy. Its price can range from 100 to 150 rubles.
  • Okomistin is an eye drop that is also used in otolaryngology. The cost of a 10 ml dropper bottle starts from 130 rubles.

There are also more expensive medications that effectively cope with ENT infections. For example, people often ask which is better - Rinofluimucil or Isofra, the cost of which is approximately the same. Firstly, it should be borne in mind that Rinofluimucil, unlike the French medicine, is not an antibiotic, but has an anti-edema, vasoconstrictor and anti-inflammatory effect. That is, it fights the symptoms, not the cause, although it is considered effective.

Secondly, it has more contraindications and is also capable of causing a greater number of adverse reactions, including those associated with heart rhythm disturbances. And thirdly, the drug is not recommended for use in children under two years of age. Therefore, the most popular medications for the common cold should be considered in more detail in comparison with Isofra.

Isofra or Polydexa - which is better for children

Both drugs are produced in the form of a nasal spray by the French company Bouchard and contain an antibiotic that acts locally, and are also prescribed for similar diseases and sold at a similar price. What makes Isofra and Polydex different is their quantitative and qualitative composition, which determines the list of contraindications.

Polydexa combines two antimicrobial compounds – neomycin and polymyxin, which significantly expands the spectrum of bactericidal activity. Dexamethasone and phenylephrine, in addition, provide a vasoconstrictor effect and relieve inflammation. In general, this medication is more effective, but it should not be prescribed to people with kidney failure, or to children under 2 and a half years of age.

Isofra or Derinat?

Children from the first days of life can be prescribed the immunostimulating drug Derinat for the treatment of ENT infections.

Sodium deoxyribonucleate, the active ingredient in the spray, is effective as part of a complex treatment and does not have a direct effect on pathogens, only strengthening the body’s defenses. Therefore, the question of the advisability of replacing this medicine can only be decided by a pediatrician or otolaryngologist.

Isofra - reviews for children

Both doctors and parents confirm the effectiveness of the French spray for runny nose and sinusitis. It quickly copes with the cause of the disease – pathogenic microflora – and alleviates the child’s condition within 2-3 days of use. By the end of the recommended course, the disease usually goes away completely without causing complications or side effects.

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Substitutes for Isofra

Infectious disease agents most often enter the human body through the respiratory system. To cope with them, the drug Isofra is recommended, which also has a lot of analogues.

How to choose a drug analogue?

When choosing analogues of the drug, you should choose a product that would be as close as possible in composition to the drug Isofra.

The main component included in Isofra drops is framycetin. This is a very strong antibiotic belonging to the aminoglycoside class. Thanks to this, the drug has a bactericidal effect, eliminating gram-positive and gram-negative microorganisms that cause infectious diseases in the upper respiratory tract.

The medicine is released in the form of a nasal spray, which is often mistakenly called drops. Since Isofra has low absorption, no studies have been carried out on it. For this reason, the pharmacokinetics of the drug has not been established.

The drug is prescribed for various diseases, including:

  • rhinitis;
  • sinusitis (only if the septum is not damaged);
  • nasopharyngitis;
  • treatment of inflammation after surgery;
  • prevention of inflammatory processes.

The only contraindication to the use of Isofra is an allergy to the main or any of the additional components. You can also cancel the course of treatment if no noticeable improvements appear within a week.

A small number of contraindications explains the popularity of the drug for treating children, even infants. But during treatment it is necessary to exercise caution, since the active component of the drug is an antibiotic that can harm the body. Taking the drug incorrectly can cause microflora disturbances or provoke allergies in the child. However, framycetin may not cause very serious illness. Studies have been conducted to confirm the safety of Isofra for children.

The drug can be used during pregnancy, since not a single case has been established in which Isofra components harmed the child.

Today, there are many analogues of the drug Isofra, containing different components that differ in the spectrum of action or price. When choosing a drug, you can choose the one that will cost less. Drugs that are less expensive will also be quite effective.

Bioparox is a generic drug Isofra

One of the most effective medicines for the treatment of the upper respiratory tract is Bioparox, a drug in the form of a spray. This drug is made on the basis of fusafungine, which can relieve swelling and inflammation of the respiratory tract. The antibiotic has a powerful effect against pathogens of infectious and other diseases:

  • Candida fungus;
  • staphylococci;
  • strains of Neisseria bacteria;
  • mycoplasma;
  • anaerobic bacteria.

The properties of fusafungine are questioned by some, since there are no studies confirming its effectiveness. But at the same time, a drug based on this antibiotic is successfully used to treat diseases and has established itself as a high-quality and effective medicine.

Bioparox is available only in the form of a nasal spray, intended for local use - irrigation of the respiratory tract. In addition to fusafungin, Bioporox contains natural ingredients: extracts of mint, rosemary flowers, cumin, clove buds, wormwood and anise oils and some other components. Another component of the spray is ethanol.

The dosage of the spray is equal to one spray. One dose (spray) consists of 125 mg of medication. One bottle of Bioporox is enough for 400 sprays.

The course of medication can last up to 7 days. The drug must be injected daily and quite often, every 4 hours. 4 sprays should be given into each nostril. When treating the respiratory tract of a child, inhalations can be performed less frequently - every 6 hours.

Inhalation can be carried out in different ways: through the nostrils or mouth. Your doctor will advise you on the appropriate method of inhalation.

Analogue of the drug Isofra - Rinofluimucil

Another analogue of Isofra is the drug Rinofluimucil. It is a mucolytic drug that can constrict blood vessels.

Unlike Isofra and Bioporox, this drug contains two active elements - acetylcysteine ​​and tuaminoheptane. The drug thins mucus and separates phlegm. Acetylcysteine ​​protects the respiratory system from toxins and removes pathogenic organisms from the body. Tuaminoheptane reduces swelling due to its vasoconstrictor effect. Thus, the drugs allow for comprehensive treatment, and after just a few days the runny nose can be completely cured.

Rinofluimucil is most often prescribed for the treatment of rhinitis, especially acute rhinitis, accompanied by the release of a thick secretion (purulent, mucous). Sinusitis and chronic rhinitis are also considered indications for use.

Hypertension, bronchial asthma, and angina pectoris are not absolute contraindications, but if these diseases are diagnosed, Rinofluimucil should be used with caution. Also treat upper respiratory tract diseases in children under 2 years of age with caution.

The drug is generally safe for patients; side effects are very rarely observed: a sharp decrease in blood pressure, rapid heartbeat, tachycardia, tremor, and agitation. Local reactions may occur: skin allergies, dry nasal mucosa.

The information published on this site is for reference only. Before using it in practice, be sure to consult your doctor.

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Source: http://gidomed.ru/lekarstva/izofra-analogi.html

List of analog drugs cheaper than Isofra

Isofra is a bactericidal antibiotic belonging to the group of aminoglycosides. A drug for local use in otolaryngology (ENT). Used for preventive purposes and treatment of infectious diseases (rhinitis, sinusitis, nasopharyngitis) and inflammation caused during the postoperative period.

Application

Adults are recommended to use one injection up to 5 times a day. For children up to 3 times a day, the dosage is the same.

Duration of treatment is 7 days.

Isofra spray has contraindications: individual intolerance to framecitin, washing of the nose and sinuses is excluded, as well as children under 1 year of age.

Composition and release form

1 ml of Isofra contains: Framecithin sulfate – 12.5 mg (8000 IU). As well as additional substances: distilled water, citric acid, sodium chloride, sodium citrate and methyl parahydroxybenzoate.

Isofra spray is available in translucent polyethylene bottles with a 15 ml spray dispenser, packaged in a box with instructions.

Properties

The drug is used in combination with other medications for infectious diseases of the nasal cavity.

Infectious inflammatory processes:

  1. Rhinitis;
  2. Sinusitis (if the nasal septum is not injured);
  3. Rhinopharyngitis.

Cost in pharmacies

The selling price of Isofra nasal spray ranges from 280 to 339 rubles.

Comparison of Isofra analogues

Analogs of Isofra spray, which are most suitable in composition.

Framinazine

The most suitable analogue drug. This is an antibiotic that effectively fights infectious inflammatory processes. Framinazine is also used to prevent the occurrence of inflammation in the postoperative period. The course of treatment is no more than 10 days. The cost of the drug is from 100 to 220 rubles.

Rhinostop

The active substance is xylometazoline. It relieves swelling and has an antibacterial effect. Used for respiratory diseases.

  • Glaucoma;
  • Hypertension;
  • Atrophic rhinitis;
  • Tachycardia;
  • Pregnancy (breastfeeding);
  • Allergy.

Price from 30 to 100 rubles.

Xylometazoline

Inexpensive analogue, has a vasoconstrictor effect, not an antibiotic. Used to treat rhinitis, sinusitis and respiratory diseases.

Cost from 50 to 80 rubles.

Miramistin

The active substance of the drug is chloride monohydrate (benzyldimethyl group). Indications for use: otitis media, tonsillitis of all types and sinusitis. It is a good substitute for Isofra spray. Price rubles.

Nesopin

The active substance is oxymetazoline, which relieves swelling of the mucous membrane and constricts blood vessels. Treats otitis media, sinusitis and other infectious diseases of the nasal cavity. Not recommended for use during pregnancy, breastfeeding and children under 2 years of age. Cost rubles.

Chlorophyllipt

It is natural and contains herbal extract. This drug is a worthy replacement for Isofra. It is not recommended for use in children prone to allergic reactions. The price varies within rubles.

Grippferon

Fast-acting antiseptic drug. There are contraindications in the form of allergies to individual components of the medicinal composition. Cost rubles.

Reviews from doctors and patients

Doctors and patients are satisfied with Isofra and recommend it to people with diseases of the nasal cavity.

Reviews from doctors

Alekseeva A.V.

Isofra contains flamecitin, an antibiotic with antibacterial properties. The course of treatment with this drug is no more than 1 week. It is important to follow the included instructions and strictly follow the dosage. It is recommended to complete the course of treatment to avoid mutation. There are no complaints about the quality.

Talipov A. G

Isofra is a spray (antibiotic) that suppresses infectious inflammation in the nasal cavity. Adverse reaction: allergy. There are also contraindications in the form of intolerance to individual components contained in the antibiotic.

Personal experience has shown that purulent runny nose and green nasal mucus disappear on the 3rd day of using the spray. Using 3 times throughout the day, on the second it becomes easy to breathe, on the third the runny nose disappears. The drug is topical, so it does not penetrate into the blood and does not have a negative effect on the body.

Patient reviews

Svetlana, 30 years old

Great medicine. The child is often sick, diagnosed with acute rhinitis. We tried various sprays and drops, and decided on Isofra - a good drug, it helps. I also liked the spray bottle, very convenient.

Dmitry, 36 years old

I liked the drug Isofra because it immediately relieves swelling of the mucous membrane, it is easier to breathe, and nasal mucus stops flowing.

Evgeniya, 27 years old

My daughter has a constant runny nose, and I approached this problem lightly; children often get sick. And the last time it turned into sinusitis, green nasal mucus started flowing, and I seriously thought about it.

On the recommendation of the pediatrician, we started taking Isofra and if we compare how we were sick for 10 days before, then with the antibiotic everything went away in 4 days. The purulent nasal mucus became transparent and after the course of therapy, the sinusitis disappeared.

Alexander, 32 years old

I recommend not quitting if the symptoms have gone away within two days, as strains of microbes may appear. Complete the entire course of treatment, but do not use it for mild manifestations of the disease; after all, this is an antibiotic spray.

Before use, you must consult with an otolaryngologist and complete the entire course of treatment in order to completely get rid of the infectious disease of the nasal cavity.

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Isofra: cheap analogues, instructions, list of cheaper drugs

The off-season has arrived again - a time of rampant viruses, bacteria and other infections, ready to attack the body of adults and children at any moment. The nasal passages are the first to enter the “battle”, stopping pathogenic microflora on the mucous membrane, of course, if the local immunity is able to overcome the pests.

The immune system of our citizens wants to be the best, and, unfortunately, viruses and bacteria often defeat the weakened microflora of the nasopharynx. A banal runny nose becomes more complicated, microbes join it, thick, hard-to-clear green snot appears, complete nasal congestion, and other delights of bacterial rhinitis.

It is for such cases that French scientists developed an antibacterial spray for local treatment of infectious (bacterial) runny nose - isofra. In this article we will look at the cheapest analogues of isofra and compare their effectiveness.

Scrolling through the forums, we can conclude that patients rarely turn to official instructions, but more often seek advice from discussion participants, or use search engines to try to find non-existent forms of isophra and its analogues. For example, the question is asked about where to buy isofra drops, what is their price? And the answer is simple - there are no isofra drops.

To select analogues for isofra, we will first study the brief instructions for the drug, on the basis of which an adequate review of analogues and their comparison will be made.

Composition and form of the drug

Isofra has only one form - a spray (polyethylene bottle with a spray nozzle), which contains 15 ml of framecithin sulfate (aminoglycoside) + excipients: distilled water, citric acid, sodium chloride, methyl parahydroxybenzoate. The drug is used only intranasally.

The cost of isofra (15 ml) in pharmacies ranges from 270–330 rubles, with an average of 290 rubles.

Pharmacological properties

Isofra is effective against a wide range of bacteria, including staphylococci, streptococci, enterobacter, proteus, and others. But there are also bacterial colonies against which isofra is powerless: anaerobes, some types of streptococcus, and a number of other pathogens.

It should be noted! If isofra is ineffective, during the first two days, the spray should be replaced with another analogue, for example, Polydex.

ATTENTION! WE RECOMMEND

For the treatment and prevention of runny nose, sore throat, ARVI and influenza in children and adults, Elena Malysheva recommends the effective drug Immunity from Russian scientists. Thanks to its unique, and most importantly 100% natural composition, the drug is extremely effective in treating sore throats, colds and strengthening the immune system.

Indications for use of isofra

Isofra is indicated for the complex treatment of the following pathologies:

  • complicated runny nose with thick and green snot;
  • bacterial rhinitis;
  • nasopharyngitis;
  • sinusitis (with an intact septum);
  • prevention of infection after nasopharyngeal surgery.

Contraindications

The drug is not used in cases of individual intolerance to framecitin sulfate, in which complaints of allergic reactions and gastrointestinal disorders may occur. The use of the drug is not recommended for more than 10 days, because the development of candidiasis of the nasal and pharyngeal mucosa is possible. Uncontrolled instillation leads to addiction and ineffectiveness of the product.

Isofra is contraindicated for children under one year of age, although there are certain studies that prove the safety of Isofra spray in early infancy, i.e. The drug can be used 30 days after birth. Many practicing ENT doctors, especially in hospitals, prescribe isofra for up to a year, because it is an excellent alternative to many systemic antibiotics.

There is no data on the use of isofra during pregnancy and breastfeeding, so the decision remains with the doctor.

Dosages

The course of injections with isofra spray is usually 5–10 days, on average it lasts 7 days.

  • one spray into each nostril up to six times a day.
  • the dosage is half as much, i.e. one spray into each nostril up to three times daily.

The position of the bottle during use should be vertical.

How to treat a runny nose in a baby (review of the use of Isofra)

Isofra - list of cheap analogues

Isofra has no structural analogues, therefore, for an adequate replacement, you need to find a cheap or expensive drug that will be almost similar to the effect of the drug in question. First of all, you need to remember that isofra is an antibiotic, so the search should begin with this pharmacological group, followed by antiseptics.

If a drug is selected for children, then the primary criterion is not always to find cheaper analogues, because the cheapest drugs are unlikely to be able to replace an antibiotic of this class, and parents cannot wait to see a healthy child as soon as possible. Therefore, loved ones are willing to pay any price to treat young patients. When a drug is chosen for adults, the price will most likely take first place.

Let's make a list of isofra analogues and determine which ones are cheaper.

  • polydex (spray, 15 ml) – 320 rubles;
  • sialor (protargol 2%, 10 ml) – 260 rubles, you can purchase protargol in prescription departments, price up to 100 rubles;
  • chlorophyllipt oil 2% (20ml) – 145 rub.;
  • collargol - prepared in the prescription departments of pharmacies, price up to 100–150 rubles;
  • octenisept (solution, 50 ml) – 570 rubles;
  • Bactroban (nasal ointment, mupirocin 2%) – 500–600 rubles;
  • Okomistin (eye drops, 10 ml bottle) – 140 rubles (also used for the nose);
  • miramistin (solution 0.01%, 50 ml) – 240 rubles;
  • bioparox (aerosol, 10 ml) – 300 rubles.

Analyzing the prices for isofra analogues, we can conclude that only drugs related to antiseptics - protargol, collargol, miramistin, chlorophyllipt, okomistin - will be cheaper. Antibacterial analogues - bioparox, polydex are almost the same in price, sometimes there is only a slight difference, it is in the range of 30–50 rubles.

When choosing a remedy for bacterial rhinitis, the question arises: “Which drops will be more effective, what is better to prefer, for example, isofre or polydex?” Indeed, local antibacterial agents have their own characteristics, some consist of one antibiotic, others of several. So what should you choose?

Isofra or Polydex – which is better?

The antibacterial drugs in question are produced by one French manufacturer, are used to treat infectious rhinitis and sinusitis, and have almost the same price. The maximum course of taking isofra and polydex is 10 days. This is where their similarities end.

The main distinguishing feature is the composition. Isofra is a mono product consisting of only one active antibacterial substance - framecithin. Polydexa is a complex of two antibiotics (polymexin B sulfate and neomycin sulfate), as well as phenylephrine hydrochloride (adrenergic agonist) and dexamethasone sodium metasulfobenzoate (glucocorticoid).

This difference makes it possible to assert that Polydexa is therapeutically stronger, and in addition to eliminating bacteria, it is also capable of eliminating inflammation and all kinds of manifestations of allergic symptoms.

Parents often ask the doctor what is better than Polydex or Isofra for their child? The answer to this question depends, firstly, on the age of the child, and secondly, on the clinical manifestations. Isofra is prescribed after 12 months of life, and Polydex only starting from 2.5 years. If children are prone to allergies, Polydex will be the best. Although, for uncomplicated forms of bacterial rhinitis, it is still better to stick to mono drugs.

If a runny nose has just begun, green snot appears, but it comes out easily, it is better to start treatment with isofra. If it is ineffective, the drug is replaced with Polydex. It should be noted that for sinusitis, in most cases, Polydex is more effective.

Isofra is “lighter” in composition and has fewer side effects. If the picture of complicated rhinitis is clearly expressed, you will have to resort to a complex antibacterial spray - Polydex. These drugs are not saline solutions, and therefore require clear doctor’s recommendations.

Many patients are confused about the identity of these drugs, believing that there is no difference between them, and they are just antibiotics. Unfortunately, this opinion is not uncommon on forums, and the worst thing is when participants give incorrect advice to each other regarding any antibacterial drugs.

Unlike isofra, polydex is available in another form - in drops, and is used to treat otitis media.

Dr. Komarovsky to the question: “Which is better isofra or polydex?” answers as follows. He says that he is not a supporter of prescribing these remedies for green snot. The main reason for Komarovsky’s attitude towards the use of isofra, polydex and bioparox is skepticism regarding the benefits of these sprays.

According to Russian scientists, the drugs in question are able to completely cure green snot in 60% of patients on the fifth day. There is also information that Polydex and Isofra for adenoids in children after 7 days of use effectively relieves inflammation, which is confirmed by x-ray monitoring.

Isofra or rhinofluimucil - which is better?

The similarity of these products lies only in the fact that they are produced in the form of sprays and are used to treat a runny nose. What to prefer - rhinofluimucil or isofru - is up to the doctor to decide, because The presented products belong to different pharmacological groups and have different compositions. The manufacturers of the products are different, Isofra is made in France, Rinofluimucil is made in Italy.

In principle, they cannot be called analogues, because rinofluimucil does not replicate either the composition of isophra or the mechanism of action. If we call rhinofluimucil an analogue, then only as a nasal remedy for the common cold.

Rinofluimucil has a vasoconstrictor (decongestant) and mucolytic effect (thin the mucus). The main active ingredients are tuaminoheptane sulfate-acetylcysteine ​​and acetylcysteine. The drug is prescribed for rhinitis of various etiologies, which is a significant difference from isophra.

Isofra is a pure antibiotic (framycetin) that eliminates bacteria. For other types of rhinitis, the remedy is ineffective and can be harmful.

As for contraindications, rinofluimucil has more of them. The permissible age for both drugs is from 12 months of a child’s life. Although for rinofluimucil, the instructions include a disclaimer that the drug should be used with caution for up to three years. In practice, this remedy has been used for years under the supervision of a doctor.

Comparing prices, we can say the following: rinofluimucil is about 30–50 rubles cheaper. The average price in Russian pharmacies is 260 rubles.

Isofra or bioparox – what to choose?

The drugs are not structural analogues, but belong to the same pharmacological group - antibiotics for topical use. The main task of these products is to fight microbes and eliminate inflammation in the area of ​​use.

The active ingredient of bioparox is fusafungin, and that of isofra is framecithin sulfate.

Bioparox is used not only for the treatment of bacterial rhinitis, but is also widely used for diseases such as laryngitis, pharyngitis, tonsillitis, rhinopharyngitis. The drug contains an additional nozzle that allows injections through the mouth.

Unlike isofra, bioparox is prescribed only from 2.5 years of age, because there is a possibility of laryngospasm. Bioparox is also prescribed with caution for allergy sufferers prone to bronchospasms. Bioparox is more likely to cause various side effects.

The price for isofra and bioparox is almost the same, minor fluctuations up to 50 rubles are possible.

How to treat runny nose and sinusitis in children

Protargol or isofra?

The drugs differ in their action. Isofra is an antibiotic, protargol is an antiseptic.

Protargol consists of active silver molecules that have a pronounced antiseptic, astringent and anti-inflammatory effect. It has been proven that, unlike isofra, protorgol also has a detrimental effect on viral infection. This antibacterial and antiviral effect is achieved by forming a protective film on the surface of the mucosa, onto which proteins of silver ions are deposited.

Unlike isofra, protorgol solutions are widely used not only in otolaryngology, but also in ophthalmology, urology and other fields of medicine.

The duration of taking protorgol, in the absence of allergic reactions, may be longer than that of isofra, because the product does not cause candidiasis of the mucous membranes.

After several instillations of protorgol, the chain of inflammatory reactions is eliminated, blood vessels narrow, and the sensitivity of the nasopharyngeal mucosa decreases.

The main indications for the use of isofra are bacterial rhinitis and nasopharyngitis, as well as sinusitis. Protorgol is most often used for bacterial rhinitis, purulent processes in the paranasal sinuses, green thick snot, conjunctivitis, blepharitis, adenoids and other diseases. From the above data it is clear that the range of “work” of protargol is much wider.

The main advantage of protargol is its price. Prescription preparation of 1 and 2% solutions rarely costs more than 100 rubles. Therefore, if you have a prescription, you can always order a fresh solution of this product. As an alternative, there is a ready-made protorgol - sialor, but its price will be more expensive (260 rubles), which is already approaching the price of isofra (290 rubles). Otolaryngologists prefer freshly prepared solutions of this remedy. Protorgol or isofra is the doctor’s choice; only a correct diagnosis will tell you which remedy will be best.

Having studied the list of possible analogues of isofra, it is easy to notice that all antibacterial agents are not cheap, but have approximately the same price as that of isofra. Antiseptics are cheaper, often not inferior in effectiveness and spectrum of action, but their effect is still weaker than antibacterial drugs.

Only a doctor can help you choose the right analogue, taking into account the patient’s age, clinical case and allergy history. Don't self-medicate! Follow this rule, the main thing is not to cause harm, and an otolaryngologist will always help with treatment. Be healthy!

And a little about secrets.

If you or your child are often sick and are treated with antibiotics alone, know that you are only treating the effect, not the cause.

So you simply “spare” money to pharmacies and pharmaceutical companies and get sick more often.

STOP! Stop feeding someone you don't know. You just need to boost your immunity and you will forget what it’s like to be sick!

There is a way for this! Confirmed by E. Malysheva, A. Myasnikov and our readers! Read more.

Source: http://lor-explorer.com/lekarstva-ot-nasmorka/izofra-deshevye-analogi-instruktsiya-spisok-preparatov-podeshevle

We are looking for an analogue of Isofra

"Isofra" is a spray for intranasal use that has antibacterial properties. The popular antibiotic successfully copes with inflammatory processes in the nasopharynx caused by the development of microbes.

However, it is not recommended to use Isofra for a long time, since it can lead to dysbacteriosis of the nasal mucosa. To eliminate cold symptoms, doctors advise using gentle analogues of the drug.

Why are analogues needed?

Before looking for an analogue of Isofra, you should read the instructions for using the nasal spray.

It is an effective antibacterial agent that helps improve local immunity.

The spray is designed to eliminate infectious diseases that occur in the nasopharynx and paranasal sinuses.

At the same time, the antibiotic has disadvantages that force consumers to look for analogues of the product.

  • Inability to fight rhinitis of viral etiology;
  • Impossibility of use for the treatment of small children;
  • The appearance of dysbacteriosis with prolonged use of the spray;
  • The cost of the antibacterial drug is quite high.

What properties should an analogue have?

"Isofra" belongs to the antibacterial agents of the aminoglycoside group. The drug contains framycetin, which actively fights gram-positive and gram-negative microbes. But, as already mentioned, it is undesirable to use an antibiotic to treat children, since it can cause an allergic reaction and dysbacteriosis.

Does Isofra have any analogues? It is immediately worth noting that the antibiotic has no analogues for the active substance. However, in pharmacies you can find products for intranasal use that are similar to Isofra in their pharmacological group.

To effectively combat inflammation in the nasopharynx, analogues must have the following properties inherent in an antibiotic:

  • anti-inflammatory;
  • wound healing;
  • decongestants;
  • disinfectants;
  • moisturizing.

In addition, for the treatment of children, it is advisable to select drugs of combined action. They must have not only antimicrobial, but also antiviral properties.

In this case, the use of the medicine will be advisable in the treatment of such diseases:

List of the best analogues

What substitutes for Isofra are indicated for use to eliminate inflammation in the nasopharynx in children and adults?

Some of the most effective agents similar in action to antibiotics include:

Before using drugs, you need to read their instructions for use and consult with an otolaryngologist.

Each of them has a specific composition, so not all types of drugs can be used in treating children.

"Bioparox"

Aerosol "Bioparox" is one of the best generics of "Isofra". The antibiotic is available in the form of a spray and, according to the instructions for use, has approximately the same pharmacological effect. It contains fusafungin, a substance with a powerful antibacterial effect.

"Bioparox" fights the following types of microorganisms:

  • staphylococcus and mycoplasma;
  • anaerobic microbes and Candida;
  • microbial strains Neisseria.

The nasal spray can be used to treat children over 12 years of age, but not longer than 5-7 days in a row. To do this, 1-2 doses of the medicinal composition are instilled into each of the nasal passages no more than 3-4 times a day.

Contraindications for the use of Bioparox include:

  • sensitivity to the components of the product;
  • children's age (up to 11 years);
  • predisposition to bronchospasms.

"Rinofluimucil"

Nasal spray "Rinofluimucil" is one of the best analogues of "Isofra", which has a vasoconstrictor and mucolytic effect. Unlike the original, the medicine contains two active ingredients: tuaminoheptane and acetylcysteine.

As indicated in the instructions for use, the spray can be used for the following diseases:

Like the original drug, Rinofluimucil has a convenient dispenser, which greatly facilitates its intranasal use. The dosage for adults is 2 doses in each nasal passage three times a day, and for children - no more than 1 dose three times a day.

However, doctors do not recommend using the spray if you have:

"Framinazine"

Framinazine is an antibacterial drug belonging to the group of aminoglycosides. The nasal spray is active against most strains of bacteria that cause inflammation of the nasopharynx. The active component of the product, framycetin sulfate, damages the cytoplasmic membrane of pathogens, preventing their reproduction.

According to the instructions for use of the drug, it can be used to combat the following problems:

How to use the spray? To treat adults, 1 dose of solution is injected into each nasal passage 5-6 times a day, and when treating children, the procedure is performed no more than 3 times a day.

The main contraindications for the use of antibiotics include:

  • hypersensitivity of the mucous membrane;
  • secondary immunodeficiency.

Features of choosing analogues

Before choosing a substitute for Isofra, you need to read the instructions for its use in more detail. This will help you decide on a group of drugs that fight the same types of diseases.

Moreover, when choosing an analogue, you need to take into account the following criteria:

  1. Release form of the medicine. For intranasal use, it is better to choose medications in the form of sprays or drops. This makes it easier to control the dose of the administered drug (Rinofluimucil, Framinazine);
  2. Composition of the medicine. To treat children, it is advisable to use products that contain components of plant origin. They do not dry out the mucous membranes and do not cause irritation (“Bioparox”);
  3. Cost of the drug. If the course of treatment is at least a day, it is more advisable to use nasal agents, which are cheaper than Isofra (Protargol, Fugentin).

When choosing analogues of Isofra, you need to focus on the principle of action of the drug, its versatility and safety in the treatment of children. The best antibiotic analogues include Rinofluimucil and Bioparox.

Source: http://prostudynet.ru/lechenie/preparaty/analog-izofry