Children's antibiotic suprax suspension

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Antibiotic Suprax for children

The antibiotic Suprax for children is produced by Jazira Pharmaceutical Industries, whose head office is located in Saudi Arabia. Suprax belongs to the category of semi-synthetic, broad-spectrum 3rd generation cephalosporin antibiotics.

Table of contents:

The drug contains cefixime tridigrad. For older children, Suprax is available in capsule form (200, 400 ml). In pediatrics, Suprax is widely used for the treatment of sore throat in children under one year of age in 60 ml vials, which contain granules for preparing a suspension (100 ml).

Suprax is a drug of the cephalosporin group, available in the form of tablets and suspensions, suitable for oral administration.

The pharmaceutical industry offers a considerable arsenal of antimicrobial and bactericidal agents for oral administration. When considering the usual methods of administering antibiotics (via injection), the most gentle method for treatment in pediatrics is to administer the drug orally. The parenteral method of taking the medicine is considered the main method of treating ENT diseases. Another advantage of such drugs is the precise dosage of the drug and high peak concentration.

The most important task of pharmacology is the creation of new drugs that reduce the number of doses, not only with a wide spectrum of action, but also with reduced toxicity, which is very important in pediatrics. The use of drugs orally definitely reduces the likelihood of infection propagation, reduces the workload of medical personnel and makes it possible to treat both in a clinic and inpatient setting.

Instructions for use

The antibiotic Suprax for children is prescribed for infectious and inflammatory diseases caused by infectious agents, harmful bacteria that cause otolaryngological infections, which most often manifest themselves in the form of cough and sore throat. Suprax is also effective for diseases of the genitourinary system and gonococcal infections. In cases of problems with the respiratory organs, as well as in the treatment of relapses and chronic infections, Suprax can be used to treat children from the age of six months, both within the clinic and at home.

Suprax compares favorably with its cheaper analogs and is one of the most effective antibiotics for treating children at home from a very early age. It has a light strawberry aroma and is easy to use, well accepted by the body, which is important when treating a child. The antibiotic Suprax is prescribed by the attending physician and is available with a prescription. The exact dosage of the drug is clearly described by the manufacturer in the instructions for the drug. One of the advantages of Suprax is that it can be taken both before and after meals and the effectiveness of the drug is not reduced.

The half-life of Suprax is much longer than that of similar antibiotics; in the case of treating young children, this is an undeniable advantage, since you can take the medicine only once every 24 hours.

How to take as capsules

Antibiotic dosage for children 12 years of age and older, weighing 50 kg or more, the drug is prescribed in the amount of 400 mg in one dose, or 200 mg every 12 hours. The duration of the course of medication depends on the complexity of the disease. As a rule, for gonorrhea without complications, take 400 mg of Suprax once. For more complex streptococcal infections, an antibiotic should be taken for at least 10 days, 200 mg of antibiotic every 12 hours. If the child’s well-being improves, it is better to reduce the dose to 200 mg every 24 hours.

Preparation of the suspension

First of all, you need to shake the contents of the bottle. Measure out the required amount of the drug. Boil 40 ml of water. Cool boiled water to degrees Celsius. Mix the suspension with boiled water thoroughly until the components are combined. Then you should wait 5-7 minutes until the suspension settles. The granules should completely dissolve in water. The prepared suspension must be shaken before use.

How to take as a suspension

The intake of Suprax suspension is calculated based on the formula (8 mg of antibiotic per 1 kg of body) for small children aged 6 months and older. Or 4 mg of the drug 2 times every 24 hours. For children 5-11 years old, the dose of the drug is 6-10 ml of suspension, at the age of 2-4 years - 5 ml, at the age of 6 months. up to 1 year – 2.5-4 ml. at 24 hours. Adults and children over 12 years of age weighing 50 kg or more should take the antibiotic 400 mg once or 200 mg twice a day. The most common duration of drug treatment is 5-10 days. In more severe cases, Suprax is taken for at least 10 days. It is also possible to adjust the dose of the drug if there is deterioration in kidney function and for patients undergoing hemodialysis.

Contraindications of the drug

In general, Suprax is easily tolerated and, with the correct dosage, does not cause complications in children. Long-term treatment with Suprax may lead to dysfunction of the intestinal microflora, manifested by colic, bloating, and diarrhea. This can be easily avoided if you combine taking Suprax with taking medications that contain lactic acid bacteria and normalize intestinal function.

Suprax is contraindicated for people allergic to penicillin and cephalosporin antibiotics.

Allergic reactions are possible, manifested on the skin in the form of redness. When taking Suprax, it is also possible to reduce concentration and reaction speed. It is necessary to stop breastfeeding if you need to take the drug. For diabetics, please note that Suprax contains a small amount of sucrose.

Analogs

A study of the bactericidal activity of cephalosporin antibiotics of the 1st, 2nd and 3rd generations against pneunotropic viruses in bronchopulmonary infections in children showed the highest effectiveness of the 3rd generation cephalosporin. There were no significant differences in the effectiveness of antibiotics for injection and for oral use. This explains the high popularity of the drug Suprax in pediatrics.

Studies of the effectiveness and safety of Cifexime (Suprax) revealed clinical effectiveness in 89% of sick children, which was expressed in an improvement in the child’s condition on average on the 3rd day, a decrease in sputum production, a decrease in cough and signs of sore throat on the 3rd day.

Normalization of functional parameters occurred on the 10th day of treatment. Cefexime has been shown to be quite effective in combating acute inflammatory diseases of the respiratory organs in children in cases of relapse. A convenient dosage form, gentle frequency of administration, and a safe method of treatment without side effects make the drug the most promising antimicrobial agent among its analogues.

Analogues of Suprax are: Cefix, Flamifix, Fixim, Loprax, Ikzim, Pancef, Amoxiclav, Sumamed, Zinnat, Augmentin.

  • The most common analogue of Suprax for the treatment of cough and sore throat in children under one year of age is the bactericidal syrup Pancef. The popularity of Pancef in the antibiotic market is due to the fact that in some regions it is more accessible and cheaper than Suprax. Its main component is the antibiotic cefixime 100 mg per 60 ml.
  • Amoxiclav is prescribed for symptoms of tonsillitis (antibiotic tablets 1000 mg/200 mg, 875 mg/125 mg). Amoxiclav is also offered in the form of a 250 mg suspension in 60 mg tubes. It should be noted that the main active ingredient included in amoxiclav, amoxicillin, has many contraindications for the treatment of children under one year of age.
  • Sumamed is a broad-spectrum antibiotic. Available in the form of a 100 mg powder, which must be diluted in water at room temperature, 0.25 mg capsules and 0.5 g tablets. The main active ingredient of the drug for the treatment of sore throat and other inflammations of the ENT organs in children and adults is azithromycin. The cost of this drug is somewhat cheaper in comparison with analogues, since it has a number of contraindications for the treatment of children under one year of age. The instructions for use of the drug state that if the dosage of the antibiotic is not calculated correctly, the child may experience hearing loss.
  • Augmentin is an antibacterial drug for the temporary treatment of ENT infections, urinary tract infections, sepsis, and osteomyelitis.
  • Zinnat is a drug similar to Suprax. Zinnat is produced in the form of granules, which are diluted in water to obtain a 100 mg suspension. The cost of the drug is somewhat cheaper than its analogues. Zinnat is different in that it is a 2nd generation cephalosporin antibiotic, and accordingly it cannot be a full replacement for Suprax.

The price of Suprax depends on the form of release and mg dosage. The average price of the drug Suprax ranges from 280 to 580 rubles. If Suprax is replaced with a cheaper analogue, you should carefully study the instructions to make sure that the chosen drug has a similar composition and properties. The analogue must be a 3rd generation cephalosparin, the main drug in it must be cefixime. A pharmacist at a pharmacy can tell you the availability of such drugs and correctly calculate their dosage. You should not listen to the advice of ordinary users without medical education.

Source: http://lecheniedetej.ru/preparaty/antibiotiki/supraks.html

Suprax suspension for children: instructions for use

The use of antibiotics to treat children often raises questions among parents. However, new generation drugs, such as Suprax, cause virtually no harm, but help the child’s body cope with serious infections. The main thing is to strictly follow the instructions and recommendations of the doctor.

Release form

Suprax is produced in several formats: 400 mg capsules, granules for preparing a suspension, and dispersible, i.e. soluble Suprax Solutab tablets. Previously, 200 mg capsules were produced, but they are now discontinued. Regardless of what form of medication is used for treatment, Suprax and Suprax Solutab are always taken orally, that is, by mouth.

The granules look like balls of small diameter, white or pale beige. At production, capsules are packaged into bottles. The box also contains a syringe or measuring spoon to measure out the required amount of water. A suspension is prepared at home according to the instructions for using the drug. Dissolving in water, the granules turn into a suspension - a suspension of small solid particles that smells like strawberries. This special children's form of "Suprax" is very convenient for small children who do not know how to swallow tablets and capsules.

The pleasant taste and smell, combined with a neutral color and familiar consistency, similar to puree or cottage cheese, does not cause a negative emotional reaction to the medicine in children.

Each bottle contains about 35 grams of granules, which, after contact with water, turn into a suspension with a concentration of the main active ingredient of 100 mg per 5 ml.

Sometimes granules are confused with capsules, but it is important for parents to remember that these are different forms of the drug. Capsules contain a higher content of active substance, so they have age restrictions for use.

A ready-made suspension is also not produced, therefore, when purchasing medicine at a pharmacy, you need to be careful.

Compound

The dosage of the drug is of great importance in the treatment of children, since Suprax is a 3rd generation cephalosporin antibiotic. The main active component of the drug, the antibiotic cefexime, is contained in the drug not in its pure form, but in a compound. So the main component is able to remain in the stomach.

In 35 grams of granules in one bottle, the content of cefixime trihydrate is 1.4 grams. When water is added, a suspension is obtained with a concentration of the main component of 100 mg per 5 ml.

Recently, many parents have been negative about treating their children with antibiotics. This makes some sense, since these substances have side effects that can harm a developing organism.

However, not all so simple. Antibiotics, invented at the beginning of the 20th century, revolutionized medicine, simultaneously increasing its ability to treat a wide variety of diseases. Previously, diseases such as pneumonia, peritonitis, any acute inflammation, including purulent wounds, were actually fatal, since only the strongest people survived. As a result of epidemics of plague, typhoid, and cholera, entire cities died out.

Just remember the Spanish flu pandemic, a common flu that killed 5% of the world’s population. But after the invention of penicillin, which became the first of this group of drugs, doctors literally began to work miracles, curing seemingly hopeless patients.

Later, doctors noticed that widely used antibiotics were helping less and less, but the next generation of drugs appeared, and again everything happened all over again: high efficiency was replaced by an almost complete lack of effect. Scientists have found that bacteria and viruses are able to adapt to the action of antibiotics, becoming resistant to them, producing special substances - beta-lactamases. This means that antibiotics are not omnipotent.

But science does not stand still. Scientists around the world are constantly working on new drugs that can defeat diseases. One of these substances is cefexime, the action of which overcomes the protection of beta-lactamases. At the same time, possible negative consequences of treatment are minimized.

In addition to the main substance, Suprax granules also contain auxiliary substances. These are xanthan gum, sodium benzoate, strawberry flavor and sucrose. If the purpose of the last two components does not need to be explained, then why the other two are needed requires clarification. Xanthan gum is a natural chemical compound consisting of carbon, hydrogen and oxygen. This substance is often used as a food additive, in particular, a thickener that helps create a mass of uniform consistency. It is this function that is assigned to it in Suprax granules.

Sodium benzoate, despite its similar name, is not related to gasoline. This is an acid salt that was discovered back in 1875 as a substitute for salicylic acid, the active ingredient in regular aspirin. Suprax granules use the ability of this substance to suppress pathogenic fungi. Studies conducted, including under the auspices of the World Health Organization, show its relative harmlessness when used in pharmacological doses.

Operating principle

Cefixime is a broad-spectrum antibiotic. This means that when it enters the body and interacts with harmful bacteria and viruses, the medicine does not act selectively, destroying a certain type of pathogen, but has an effect on a large number of microorganisms, including such common ones as staphylococci, citrobacter, Morgan bacteria, salmonella, proteus vulgaris .

Cefixime inhibits the synthesis of the cell wall of bacteria, thereby preventing them from reproducing, which leads to a gradual reduction in their colonies and death. At the same time, it is resistant to beta-lactamases - protective substances that bacteria secrete to protect themselves from antibiotics.

Research shows that the bioavailability of a substance, i.e. the percentage that is absorbed by the body when administered, reaches 50%. This is a very high figure for antibiotics. In addition, absorption is not affected by the interval with food intake. The main part of the drug is excreted from the body within 24 hours through urine, and partly through bile.

Indications

The bactericidal effect of Suprax makes the medicine a reliable tool for treating inflammation. In ENT practice, the suspension is used for tonsillitis - inflammation of the tonsils, pharyngitis - pharynx, sinusitis - paranasal sinuses, as well as otitis - middle ear and other inflammations of the upper and lower respiratory tract - bronchitis, laryngitis, tracheitis.

Sore throat is also an indication for treatment with Suprax, as acute tonsillitis is most often called. Most often, this disease, manifested in inflammation of the tonsils and other parts of the palatine ring, is caused by staphylococci or streptococci. But not every redness of the throat is a sore throat and requires the use of an antibiotic, especially one as powerful as Suprax.

To avoid the development of resistance, i.e. resistance to antibiotics, parents need to take a very balanced approach to their use when treating children. Children should not be given medications from this group without a doctor’s prescription.

At the same time, if the doctor recommends antibiotic treatment, then there is no need to refuse it or delay the start of treatment. This may worsen the child's condition.

Supradex suspension is also used to relieve inflammatory processes of the urinary system - cystitis, urethritis.

At what age is it prescribed?

Suprax suspension is approved for use in infants from 6 months. The instructions for use do not contain more precise parameters, but indicate that in children under six months of age, the Suprax suspension can be used strictly and exclusively as directed and under the supervision of the attending physician and only if it cannot be replaced with another drug.

From 6 months to 12 years, a suspension is recommended, for children over 12 years old - tablets and capsules. The fact is that it is the suspension that contains the optimal concentration of the active substance for young children, has a pleasant smell and taste and is easy to swallow. For older children, it will be necessary to take too large a volume of the suspension.

Contraindications

Instructions for the use of granules for preparing the Suprax suspension contain a list of cases when the use of the drug for the treatment of children is contraindicated. Firstly, this is a previously identified increased individual sensitivity or intolerance to the main or auxiliary components of the drug. Most often in practice, intolerance to the antibiotic occurs, since other components are relatively harmless.

If intolerance occurs, you should immediately stop taking the medication and inform your doctor, who will give recommendations on further actions. There is no need to continue taking it, waiting for the child’s body to “get used” to the medicine.

The second case when taking the Suprax suspension is not recommended is a serious impairment of kidney function. This is due to the fact that the medicine is eliminated from the body through the urinary system, and the kidneys thus take on additional load.

If your doctor prescribes this drug for your child, tell him or her about the condition. The specialist will make the final decision on the use of the medicine only on the basis of complete information about the child’s health condition, guided by the principle that the medicine used for treatment should bring more benefit than harm.

With caution, carefully weighing the possible consequences, the Suprax suspension is prescribed to children suffering from chronic renal failure, as well as with a disease such as pseudomembranous colitis, including a history. The fact is that this acute inflammation of the intestines sometimes occurs while taking antibiotics or other medications.

Side effects

During treatment with Suprax, children may experience unwanted side effects associated with the effect of the drug on the body.

The most common side effects are related to the gastrointestinal tract. Their manifestations are varied - from decreased or loss of appetite and dry mouth to pain, bloating, stool disorders and dysbiosis. There are cases of impaired functional state of the liver, jaundice, and pseudomembranous colitis. Some children develop stomatitis.

The central nervous system can also react to taking medication. The child may complain of dizziness, tinnitus, and possible seizures. Allergic reactions often appear on the skin in the form of rashes, redness, and itching. Swelling of soft tissues is possible, including in the area of ​​the external genitalia and face, up to Quincke's edema.

Various abnormalities can be detected by clinical blood tests. These are some types of anemia, including hemolytic, reduction in the number of leukocytes in the blood, destruction of red blood cells and others.

But if a doctor can see abnormalities in blood tests, then parents will most likely be the first to notice other symptoms. It is especially important to be attentive to the condition and behavior of young children and infants who cannot themselves report disturbing manifestations.

So, if a child cries for no reason, often wakes up at night, is capricious during the day, and refuses to eat his usual food, then you need to inform your doctor about this. Perhaps the baby is signaling through behavior that the condition is worsening due to the side effects of the medication.

The decision to cancel treatment, replace Suprax with another drug, or prescribe symptomatic treatment is made by the doctor. There is no need to cancel the treatment yourself, as this may harm the results of the treatment.

Instructions for use

Since the Suprax suspension is prepared from granules at home, you must first dilute it, following the instructions for use from the manufacturer. Each package of granules must include a special syringe for adding water or a measuring spoon. There is no need to ignore them by adding water by eye. One teaspoon of water corresponds to approximately 5 ml.

But the key word here is approximately, while to prepare the Suprax suspension, you need to measure out a certain volume of liquid so that the resulting suspension reaches the concentration of the active substance that is optimal for treating the child.

First of all, you need to prepare the water. To do this, draw 40 ml of warm boiled water into a pre-washed syringe or measuring spoon. It is important to try to measure the volume of water as accurately as possible, drain the excess, and add if there is not enough. Use water at room temperature for better dissolution.

Next, the bottle of granules needs to be shaken thoroughly to avoid them sticking together. If the granules stick together, this will prevent them from dissolving in the water. Then open the original packaging and add 20 ml of water, close the bottle, shake, stirring the contents. Then add the remaining water and repeat the procedure.

As a result of shaking, foam forms in the bottle, so you need to place it on a horizontal surface and wait a few minutes for it to settle. After this, you need to make sure that the liquid level in the bottle is at the level marked by the arrow. If there is not enough liquid, you need to carefully add it, bringing the level to the arrow, and then shake well again. The suspension is ready.

Remember to close the bottle and place it in a dark place where the child cannot get the medicine.

The dosage of the drug depends on the age and weight of the child. Only a doctor can accurately calculate the dose. In the instructions for use, the manufacturer indicates the usual doses of the drug. So, for children under 6 months, the volume of suspension that needs to be taken during the day is calculated by the formula: 8 mg of suspension for each full kilogram of weight. This volume is divided into 2 doses. This produces a single dose of the drug.

It is important that equal periods of time pass between doses. To avoid having to wake up the child during sleep, you need to calculate the moment of the first dose.

Children under one year of age are usually prescribed 50–70 mg of the active substance, which corresponds to 2.5–4 ml of suspension per day. Children under 4 years of age need to take 5 ml of suspension, which is 100 mg of active ingredient. Older children - from 5 to 11 years old - are given 6-10 ml of suspension.

These dosages are designed for children with a normal weight-to-age ratio. But for more accurate dosages you can use the table:

Volume of suspension per day, ml

The volume of suspension for a single dose should also be measured by a child using a measuring syringe or spoon. Moreover, when using a syringe, the accuracy will be higher. After use, these devices should be rinsed with warm water and wiped with a clean, dry cloth.

A child over 12 years of age should receive the adult dosage of the medicine, preferably in capsules or tablets.

The duration of treatment with Suprax is from 7 to 10 days as prescribed by the doctor. There is no need to exceed the recommended course duration, as this can lead to undesirable consequences, including dysbacteriosis. To prevent its occurrence, as a rule, probiotics are prescribed simultaneously with taking antibiotics - preparations containing live microorganisms that replenish the deficiency of their own in the intestines.

Overdose

If you strictly follow the instructions for use of the drug, it is impossible to overdose the drug. It can only occur if the child accidentally ingests a large number of granules or a volume of ready-made suspension.

Symptoms of an overdose of Suprax are the same as for side effects, but in a more pronounced form, including from the gastrointestinal tract.

If parents are sure that the child has taken the drug in a dosage greater than that recommended by the doctor, they urgently need to perform gastric lavage, calculating the amount of liquid depending on the age of the child. For washing, use a weak solution of potassium permanganate. After this, the child needs to be given a sorbent, preferably Smecta or Enterosgel, but if these drugs are not available, then activated carbon or any other. Gastric lavage is effective only in the first two hours after taking the pills.

In case of overdose, you should definitely seek emergency medical help to avoid complications.

Interaction with other drugs

"Suprax" is able to influence a wide range of drugs if simultaneous treatment is prescribed. This must be taken into account when using the medicine, including in children. So, if you give children a suspension and diuretics, as well as penicillin antibiotics, the concentration of cephexime in the blood may increase.

Do not combine Suprax with antacids (against heartburn) and absorbent drugs, as this reduces its concentration and, consequently, the effectiveness of treatment.

Terms of sale and storage

In Russian pharmacies you can purchase Suprax granules strictly according to a doctor’s prescription. Using the medicine without a doctor's prescription is strictly prohibited.

At home, before preparing the suspension, the granules are stored in an unopened bottle in a dry and dark place at room temperature. The bottle must not be heated above +25 C.

It is important that the medicine is stored out of the reach of children.

The shelf life of an unopened bottle is 3 years if the conditions are met. The release date of the drug is indicated on the packaging.

The finished suspension should be stored in a closed vial at room temperature. There is no need to put the bottle in the refrigerator. If the suspension freezes, it is no longer usable. It needs to be thrown away. The shelf life of the finished suspension is no more than 14 days.

Reviews

Parents call Suprex an effective drug that can put a child on his feet in just a few days.

For complicated ARVI, treatment usually lasts about 5 days. During this time, all symptoms of the disease usually go away, breathing becomes clear, and the cough is insignificant. The parents did not report any side effects, including those from the gastrointestinal tract.

Many mothers like that they only need to dilute the suspension once, and then use the ready-made one.

Some parents indicate that Suprax is excellent in treating bronchitis, even when another antibiotic does not provide benefit. Recovery in this case is not quick, but after a few days of use, relief usually occurs. The course of treatment is usually 5 days. During administration, the child may experience loose stools, which disappear after taking the probiotic.

Reviews from doctors also speak about the effectiveness of Suprex. Lauras often prescribe this drug because it is easy to take for children. In addition, allergic reactions are observed quite rarely, and the effectiveness of the drug is high.

Analogs

In pharmaceuticals, there are two types of possible analogues of any drug - according to the active substance and according to the therapeutic effect. If drugs have the same active ingredient, then their effect on the body is virtually identical, regardless of what brand, brand or name they are marketed under.

Analogues of Suprax are drugs such as Cefixime, Ixim Lupine, Pancef and Cefspan. For example, “Ixim lupine” is produced in India in the form of a powder for the preparation of a suspension and is approved for use in children from 6 months. "Cefpan" is also presented in the form of a suspension, the manufacturer is a Macedonian company.

In terms of therapeutic effect, the closest substitutes for Suprax are drugs whose action is based on another main component, but also part of the cephalosporin group. The list of such drugs is quite wide, we will name only a few of them: “Azaran”, “Kenfotex”, “Liforan”, “Medakson”, “Roceferin”, “Tsifosin”.

Note that all of the listed drugs are sold in the form of powder for injection. In general, cefexime is the first of its group of antibiotics approved for oral administration. Therefore, the drug has an advantage when used to treat children. In addition, granules and powders may contain excipients that differ from those contained in Suprax. This also needs to be taken into account when choosing a replacement drug.

The average price of Suprax granules in Moscow is 670–700 rubles. For comparison, “Pancef” costs about 300, “Ixim Lupine” – about 500 rubles.

Dr. Komarovsky will talk about when antibiotics are needed in the next video.

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Source: http://www.o-krohe.ru/antibiotiki/suspenziya-supraks/

Expensive, but effective - antibiotic Suprax for children: instructions for using the suspension, opinions for and against

Suprax is included in the clinical and formological group of 3rd generation cephalosporin. This drug takes pride of place in the list of antibacterial drugs due to its high efficiency and wide range of actions.

It is most effective against bacteria that are resistant to commonly used antibiotics.

In this article, we will look at the instructions for using Suprax suspension for children and tell you how to dilute and prepare the children's antibiotic for use.

Composition and release form

Suprax suspension is specially made for children and is packaged in 60 ml bottles. The bottle itself is made of dark opaque glass and is closed with a screw-on cap.

The drug itself is sold in the form of white-cream granules. To take the drug orally, it must be mixed with water and stirred until a solid liquid with a thick consistency is formed.

The active substance of Suprax is micronized cefixime trihydrate in the amount of 1.402 grams. This is equivalent to 1.2 grams of Cefixime.

Excipients include sodium benzoate, sucrose, xanthan gum and strawberry flavor.

Indications

Suprax must be taken as prescribed by a doctor due to severe inflammatory processes resulting from the action of microorganisms.

  • various diseases of the ENT organs;
  • mild forms of bronchitis, as well as chronic bronchitis;

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    Contraindications

    Individual intolerance of the body to one or more components of the drug is considered the main reason not to prescribe this drug to the patient.

    Renal failure and pseudomembranous colitis are also indications for avoiding Suprax.

    How the drug works

    The drug has a direct effect on gram-positive and gram-negative microorganisms. Thus, the synthesis of the cell membrane decreases and pathogenic bacteria become weakened. As a result of exposure to antibodies, they die.

    After administration, the bioavailability of the main drug substance does not exceed 50%.

    Can be taken regardless of meals, but if you take Suprax with food, the time required to achieve maximum effect is reduced by almost 1 hour and takes 3 hours.

    In other cases, it is necessary to wait about 4 hours to achieve maximum effect.

    The drug has a fairly high binding to plasma proteins, which is about 65%. About half of the active substances are excreted unchanged from the body along with urine.

    This occurs within the next 24 hours after taking the drug orally. 10% is excreted along with bile.

    The half-life is approximately 4 hours. If renal activity is impaired, this process increases up to hours.

    special instructions

    Some patients may experience increased sensitivity to cephalosporin antibiotics, which manifests itself in the form of allergic reactions.

    In this case, the question of using Suprax during treatment remains at the discretion of the attending physician. Disorders of the intestinal microflora are possible in case of prolonged use of the drug.

    As a result, severe diarrhea and pseudomembranous colitis cannot be ruled out.

    Suprax is not recommended for use in diabetes mellitus, as it contains sucrose. 20 ml contains 15 grams of it.

    Dosage

    At the age of 6 months to 12 years, the drug is taken exclusively in the form of a suspension. The daily dose is up to 8 mg per kilogram of body weight. Can be taken at once or divided into 2 times.

    At the age of 5 to 11 years, it is necessary to take 6-10 ml per day, children from 2 to 4 years old take 5 ml of Suprax per day, and the age group from 6 months to a year takes the drug in the amount of 2.5-4 ml per day. day.

    Children from 12 to 18 years of age can take this drug in an amount of 400 mg at a time or 200 mg twice a day.

    In each specific case, the dose of Suprax suspension for children can be reduced or increased. Your doctor should consider the potential benefits and possible harms when choosing this drug.

    Overdose and side effects

    Side effects occur extremely rarely, and most often they are caused by an overdose.

    These may include the following:

    • various allergic reactions, which usually manifest themselves in the form of a rash;
  • problems with the gastrointestinal tract, which causes constipation, diarrhea, vomiting, and sometimes abdominal pain;
  • damage to the nervous system, due to which the patient may experience headache or dizziness, as well as tinnitus;
  • problems with lymphatic causes cause disturbances in the process of blood formation in the body;
  • As a result of treatment with Suprax, the genitourinary system is susceptible to vaginitis, nephritis and impaired renal function.

    • Possibility of combination

    It is not recommended to take Suprax and sodium hydroxide at the same time, since in this case the therapeutic effect is significantly reduced.

    With the use of diuretics, the rate of removal of the antibiotic from the body increases.

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    Average price in Russia

    This drug is quite expensive, but very effective. It is available only with a doctor's prescription and costs from 500 to 800 rubles. In some pharmacy kiosks, its price can reach 1000 rubles.

    Storage conditions and shelf life

    The drug, undiluted with water, can be stored in a regular cupboard, out of the reach of children. The shelf life is 3 years.

    Reviews

    Tatyana69 wrote that her child had severe ear pain as a result of the flu.

    Body temperature reached 39 degrees. When trying to bring it down, it dropped to at least 38 degrees. They called a doctor to the house, who threw up his hands and prescribed Suprax.

    After several appointments, the temperature returned to normal and the ear pain went away.

    Ella writes that she gave her child Suprax for 7 days, but the bottle did not last for a week. Taken together with the probiotic Bifiform. At high temperatures, the child also had problems with his ears.

    After taking the course, my son began to complain that his hearing had become a little worse. The ENT specialist said that these are the consequences of a strong antibiotic and this problem is easily treated. Physiotherapy was prescribed.

    But LinaSun had no problems with the use of the antibiotic. She writes that her daughter was given only 3 days instead of the required seven. I stopped the course because the child’s condition returned to normal and she no longer saw the point in “poisoning” her daughter with antibiotics.

    For some, everything goes away in a few days without causing any complications, while for others, side effects appear that are quite easy to eliminate.

    There are also negative reviews on the Internet, but they are all related to the fact that children had individual intolerance to certain components of the drug, as stated by the authors themselves.

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    Suprax suspension for children: instructions for use, how to dilute, price, reviews, analogues

    A powerful antibiotic of the latest generation. One of the most effective today. It is used in urology, pulmonology, dermatology and ENT diseases. It is prescribed only for severe illnesses when other medications have not given the desired therapeutic effect.

    Dosage form

    Produced in Italy in the form of dispersible (water-soluble) tablets, granules (60 mg per bottle) for the preparation of an infant suspension. Both are intended for oral use.

    Pharmacological group

    Suprax belongs to the clinical and pharmacological group of 3rd generation cephalosporins, antibiotics used to treat infectious diseases and pathologies in cases where they are caused by bacteria sensitive to the effects of this drug. In the treatment of diseases caused by such microorganisms, it is used in the form of a solid medicine (tablets) or a preparation (granules) related to dry medicines and used for the preparation of a flavored children's suspension. The suspension is used in childhood without any age or localization restrictions.

    Description and composition

    The main component of the dry matter is microficheized Cefixime. Inactive ingredients include sodium benzoate, sucrose, xanthan gum, strawberry flavoring, and gum. The suspension is available in a dark glass bottle; the medicine kit includes a dispenser spoon and detailed instructions for use. The granules, usually white, cream, or yellowish in color, dissolve easily in water, the resulting substance tastes good and is easily swallowed by children. A spoonful can be 5 or 10 mg, and this circumstance must be taken into account.

    Suprax is used in really severe cases of infectious lesions, and its spontaneous administration is not permissible without medical permission, not only because the antibiotic is a selective drug and is prescribed when it is known exactly which bacteria caused the negative process, but also because it is accompanied by addiction. If the medicine is used unjustifiably, the bacteria will have time to develop resistance, and the required medicinal effect will no longer be achieved. The doctor recommends using the drug only in really severe cases. You can buy Suprax at a pharmacy only with a prescription. If the severity of the lesion or the degree of development of the pathology is not very high, a less effective antibiotic is usually prescribed.

    Indications for use

    Due to its high activity and unlimited impact on different areas of infection, the drug is widely used in:

    • otorhinolaryngology (inflammation of the middle ear, otitis, sinusitis, sinusitis, sinusitis, tonsillitis, pharyngitis, agranulocytic tonsillitis, tonsillitis);
    • urology and gynecology (gonorrhea, other uncomplicated diseases of the genitourinary system of bacterial etiology, including urinary tract infections, cystitis, urethritis):
    • pulmonology (acute and chronic bronchitis, respiratory therapy);
    • dermatology (pyoderma, boils).

    Clinical studies have shown the highest effectiveness of Suprax: in 89 cases out of a hundred, already on the third day of taking the drug, significant relief occurs, inflammation decreases, the separation of sputum or exudate decreases, and the swelling of diseased surfaces decreases. An undoubted convenience is the possibility of using the product from an early age; it is taken once a day, regardless of meals.

    Directions for use and doses

    The drug intake is calculated by the attending physician, but, according to the instructions for use, the maximum daily dose is:

    • at 6-12 months. 8 mg per 1 kg of body 1 time per day (or 4 mg with 2 doses);
    • in 2-4 years – 5 ml;
    • at 5-11 years old – 6-10 ml;
    • from 11 – 400 mg per day.

    Method of administration: oral; the required dose is measured using a measuring spoon, which is included with the drug in the package, or a measuring syringe, which can be purchased at a pharmacy. The usual period of use is a course of 10 days, although the results are already visible after 3-4. You should not stop taking the drug earlier, but there is no need to use it longer than prescribed. If discontinued early, the final result may not be achieved; if delayed, the effectiveness of use will decrease.

    Interaction with other drugs

    Antacids containing magnesium or aluminum slow down the absorption of the drug through the gastrointestinal tract, which is especially undesirable in cases of severe bacterial infection. Diuretics slow down the excretion of Suprax through the kidneys. Indirect coagulants receive a significant increase in their effect through the drug, which helps to increase the prothrombin index.

    Side effects and overdose

    There are no data on deaths occurring even with a significant overdose. Studies have shown that excessive use of antibiotics increases side effects. In case of overdose, treatment with antihistamines and glucocorticoids is practiced, other measures are symptomatic.

    Side effects can manifest themselves in the digestive system in the form of diarrhea, constipation, abdominal pain, nausea and vomiting; the drug sometimes causes headaches, tinnitus, and dizziness. Allergic reactions, functional failures of the kidneys, and changes in blood composition are extremely rare. The occurrence of side effects may prompt the replacement of the drug with another one with a similar spectrum of action.

    Contraindications

    Contraindications are considered individual immunity, or allergic reactions to individual components of the drug, significantly impaired kidney function. During pregnancy, some sources do not see any obstacles to use, but indicate the possibility of use if the expected benefit to the mother’s body does not exceed the hypothetical harm to the gestating fetus; others do not recommend its use.

    special instructions

    When using the medicine for more than 10 days, it is recommended to prescribe eubiotics or probiotics. If the patient is taking medications from other pharmacological groups, the doctor should find out about this and anticipate possible interactions. The medicine contains sucrose, which must be taken into account in case of diabetes.

    Analogs

    Instead of Suprax suspension, the following medications can be used:

    1. Pancef is a complete analogue of the drug Suprax. The medicine is produced in tablets and granules, from which a suspension is made. It can be used in liquid form for patients from six months of age. The tablets can be used to treat people over 12 years of age, including pregnant women. During therapy, the baby should be switched to formula.
    2. Azaran contains ceftriaxone as an active ingredient. It belongs to the third generation cephalosporins and is characterized by a wide spectrum of action. It comes in powder form and is used to make a solution that is injected into a vein and into a muscle. The antibiotic can be used to treat children and pregnant women.
    3. Cefobid contains cefoperazone as an active ingredient. The antibiotic is commercially available in powder form, which is diluted to form a solution for injection into a vein or muscle. The antibiotic can be used in children from birth; it can be administered during pregnancy. It is recommended to interrupt breastfeeding during antibiotic therapy.
    4. Pactocef is a combination drug. The therapeutic effect of it is explained by the cefoperazone and sulbactam included in its composition. It is produced in the form of a powder, from which a solution is made for intravenous and intramuscular administration. Pactocef can be used to treat children, including newborns. Antibiotics are allowed to be prescribed to pregnant women. It is recommended to stop breastfeeding for the entire period of therapy.

    Storage conditions

    The shelf life of the drug is 3 years; after the expiration date it cannot be used. The drug is stored in a cool, dark place, out of the reach of children; it is advisable to store it in the original factory packaging.

    Drug price

    The cost of the medicine is on average 716 rubles. Prices range from 506 to 1088 rubles.

    Source: http://zdorrov.com/instruktsii-po-primeneniyu/supraks-suspenziya-dlya-detej.html

    Suprax, suspension

    Analogs

    • Pantsef;
    • Ceforal Solutab;
    • Ixim Lupin.

    There are other suspensions that are not inferior in their properties:

    Average price online *, 578 rub. (gran. suspension 100 mg/5ml 30g)

    Instructions for use

    Suprax is a semi-synthetic antibiotic of the third generation of cephalosporins. It is characterized by a wide spectrum of action.

    Indications

    The drug is prescribed for infections caused by drug-sensitive bacteria:

    • inflammation of the middle ear;
    • uncomplicated diseases of the genitourinary system of a bacterial nature, including gonorrhea;
    • inflammation of the paranasal sinuses (sinusitis, sinusitis);
    • pyoderma, boils;
    • angina;
    • pharyngitis;
    • bronchitis, both acute and chronic.

    Directions for use and dosage, how to prepare

    To prepare a suspension for oral administration, you need to turn the bottle over and shake its contents.

    Then, in 2 stages, pour 40 ml of boiled water at room temperature into the bottle, after each addition, shake well to obtain a homogeneous suspension.

    Let it stand for 5 minutes until the powder is completely dissolved. The prepared suspension can be stored for 2 weeks at a temperature of 15-30 degrees. Shake the bottle vigorously before use.

    5 ml of the finished suspension contains 100 mg of active substance.

    Patients are allowed to prescribe it from 6 months. The daily dosage of the drug is 8 mg per kg of child’s body weight. You can take it either at one time or divide it into 2 times and drink it with an interval of 12 hours.

    The daily dosage should be calculated based on body weight, and measured with caps as accurately as possible. For example, if a child weighs 15 kg, the dose for him will be 15 * 8 = 120 mg or 1.2 caps.

    A simpler option - Recommended dosage regimens by the manufacturer:

    For persons over 12 years of age, the drug is prescribed in dosages for adults; from this age, it is allowed to take the drug in capsules.

    As a rule, the duration of therapy varies from 7 to 10 days. If the causative agent of the infection is streptococcus pyogenes, the duration of therapy should be at least 10 days.

    If the patient has kidney pathology, the dosage of the medication is reduced:

    • if he is on hemodialysis or his creatine clearance varies from 21 to 60 ml/min, the daily dosage is reduced by 25%;
    • when he is on peritoneal dialysis or CC, no more than 20 ml/min, the daily dosage should be reduced by 2 times.

    Contraindications

    The drug is contraindicated:

    • with intolerance to cephalosporin and penicillin antibiotics;
    • children under 6 months.

    The drug is prescribed with caution:

    • if the patient has suffered pseudomembranous colitis;
    • with chronic renal failure;
    • patients of the older age group.

    Prescriptions for pregnant and lactating women

    The drug can be prescribed to women in a position where the benefit to her outweighs the possible risks to the fetus.

    If you plan to take the drug during breastfeeding, then the baby must be switched to formula.

    Overdose

    If the recommended dosage is accidentally or intentionally exceeded, an increase in side effects is observed, especially from the digestive tract.

    To eliminate the symptoms of intoxication, the following are prescribed:

    Treatment is carried out to eliminate the unwanted symptoms that appear; hemodialysis and peritoneal dialysis are not particularly effective.

    Side effects

    During therapy, the following undesirable reactions may occur:

    • allergies, which can manifest as urticaria, redness and itching of the skin, an increase in the number of eosinophils, fever, anaphylaxis, erythema multiforme, Lyell's syndrome;
    • from the central nervous system, such as headaches, tinnitus, dizziness;
    • from the gastrointestinal tract, including dry mouth, lack of appetite up to anorexia, dysbiosis, excessive gas formation, pain in the abdomen, nausea, vomiting, constipation or, conversely, diarrhea, oral thrush, inflammation of the tongue, stomatitis, reduction or cessation of bile formation, inflammation of the tongue, pseudomembranous enterocolitis;
    • decreased levels of leukocytes, platelets, neutrophils, aplastic and hemolytic anemia, some patients experience pancytopenia (a sharp drop in the concentration of all blood elements), bleeding, prolongation of prothrombin time;
    • interstitial nephritis, renal dysfunction;
    • inflammation of the vaginal mucosa;
    • increased activity of alkaline phosphatase, liver transaminases, increased levels of bilirubin and creatinine in the blood, urea nitrogen;
    • candidiasis;
    • dyspnea.

    Compound

    The drug is available in granules for preparing a suspension. Their color can vary from white to light yellow.

    The finished dosage form is the same color with strawberry flavor. The medicine is produced in a dark glass bottle complete with a measuring spoon.

    The active substance is cefixime; the following are used as auxiliary components:

    Pharmacology and pharmacokinetics

    The antibiotic inhibits the synthesis of the bacterial cell membrane, which leads to its death.

    It is active against the following microorganisms:

    • group A streptococci, which cause pneumonia;
    • Escherichia coli and hemophilus influenzae;
    • gonococci;
    • Moraxella catharalis;
    • Proteus;
    • shigella;
    • salmonella;
    • Klebsiella oxytoca and pneumonia;
    • cytobacter
    • serracia marcescens.

    When taken orally, the bioavailability of the active substance varies from 40 to 50%, it does not depend on food intake, but the maximum concentration in the blood is observed faster by almost 1 hour if the medicine is taken with food.

    The highest concentration in the systemic circulation is observed 4 hours after administration. Almost 50% of the active substance is excreted unchanged through the kidneys per day, approximately 10% is excreted from the body through the intestines.

    The half-life depends on the dosage and can vary from 3 to 4 hours; if the patient has renal pathology with a CC of 20-40 ml/min, it extends to 6 hours; with a CC of 5 to 10 ml/min, it extends to 11.5 h.

    Terms of sale and storage

    The medication is dispensed strictly according to a doctor's prescription. It should be stored out of the reach of children, at a temperature of 15-25 degrees, the shelf life is 36 months.

    Reviews

    (Leave your feedback in the comments)

    [su_quote cite=”Lada”] I gave Suprax to the child for a throat problem 2 times already, the first time last year, the second time 14 days ago. It is easy to prepare the suspension; the big advantage is that it does not need to be stored in the refrigerator and does not need to be heated before giving it to the child. The child is 2 years 8 months old, weight 13 kg 300 g, the doctor prescribed us to take it 3 ml 2 times a day, course 7 days. One bottle was enough, the last dose was barely scraped together. [/su_quote]

    [su_quote cite=”Yulia”] Suprax in suspension was prescribed to us by an ENT specialist, in combination with other medications, when she started having otitis media. My daughter had no allergies or bowel problems. On the 3rd day the temperature returned to normal, and on the 5th day the daughter recovered. I especially liked that the medication should be taken once a day, regardless of food. The only negative is the high price. [/su_quote]

    * — Average value among several sellers at the time of monitoring, is not a public offer

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