Budoster spray price

Analogue of Budoster nasal spray

Budoster (nasal spray) Rating: 9

Manufacturer: Mifarm S.p.A., Via B. Quaranta (Italy)

Analogs of the drug Budoster

Analogue is cheaper from 108 rubles.

Manufacturer: Lek (Slovenia)

Table of contents:

The analogue is more expensive from 110 rubles.

Manufacturer: GlaxoSmithKline Pharmaceuticals S.A. (Poland)

Release forms:
  • Air. 50 mcg/dose, 60 doses; Price from 527 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Flixotide in online pharmacies

The analogue is more expensive from 339 rubles.

Manufacturer: GlaxoSmithKline Pharmaceuticals S.A. (Poland)

Release forms:

  • Air. called 120 doses of 50 mcg; Price from 756 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Flixonase in online pharmacies

The analogue is more expensive from 957 rubles.

Manufacturer: Dr. Falk Pharma GmbH (Germany)

The analogue is more expensive from 899 rubles.

Manufacturer: AstraZeneca AB (Sweden)

Release forms:

  • Susp. d/ing. cont. 0.5 mg/ml 2 ml, 20 pcs.; Price from 1316 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Pulmicort in online pharmacies

The analogue is more expensive from 489 rubles.

The analogue is more expensive from 848 rubles.

Manufacturer: Nycomed GmbH (Germany)

Release forms:

  • Air. 80 mcg/dose, 60 doses, 5 ml; Price from 1265 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Alvesco in online pharmacies

Analogue is cheaper from 119 rubles.

Manufacturer: Ivax Pharmaceuticals (Ireland)

Release forms:

  • Aerosol d/ing. 0.1 mg/dose, 200 doses; Price from 298 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Beclazon Eco in online pharmacies

The analogue is more expensive from 544 rubles.

Release forms:

  • Air. d/ing. forte 200 mcg/dose 200 doses, 10 ml.; Price from 961 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Budesonide in online pharmacies

The analogue is more expensive from 190 rubles.

Manufacturer: Pharmaceutical Factory of St. Petersburg (Russia)

Release forms:

  • Air. 250 mcg/dose, 200 doses; Price from 607 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Beclospir in online pharmacies

The analogue is more expensive from 165 rubles.

Manufacturer: Chiesi Pharmaceuticals (Italy)

Release forms:

  • Aerosol 0.25 mg/dose 200 doses; Price from 582 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Klenil in online pharmacies

Analogue is cheaper from 240 rubles.

Manufacturer: Teva (Israel)

Release forms:

  • Spray 50 mcg/dose 200 doses; Price from 177 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Nasobek in online pharmacies

Analogue is cheaper from 270 rubles.

Manufacturer: Danson Trading Pharmaceutical (Vietnam)

Release forms:

  • Aerosol 250 mcg/dose, 200 doses; Price from 147 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Beclomethasone DS in online pharmacies

Analogue is cheaper from 91 rubles.

Release forms:

  • R-r d/ing. fl. 0.5 mg/ml 2 ml, 10 pcs.; Price from 326 rubles
  • Air. 125 mcg/dose, 60 doses; Price from 868 rubles

Prices for Budesonide-native in online pharmacies

Source: http://www.proanalogi.ru/b/analog_spreya_nazalnogo_budoster.html

Budoster, nasal spray 100 mcg/dose, 10 ml

different from pictured

  • 🏪 You can buy Budoster, nasal spray 100 mcg/dose, 10 ml, on the website and in our pharmacies
  • 🚚 Fast delivery Budoster, nasal spray 100 mcg/dose, 10 ml, home in Moscow
  • 📲 Price for Budoster, nasal spray 100 mcg/dose, 10 ml, below in our application

Instructions for use

Active substance

Amount in a package

Dosage form

Manufacturer

Compound

1 dose contains:

active ingredient: budesonide 100 mcg

excipients: dextrose, Avicel (microcrystalline cellulose and sodium carmellose in a ratio of 9:1), potassium sorbate, polysorbate 80, disodium edetate, hydrochloric acid to pH 4.5, purified water.

pharmachologic effect

Budoster is a GCS for intranasal use. It has a pronounced anti-inflammatory and antiallergic effect. When used in therapeutic doses, it has virtually no resorptive effect. It does not have mineralocorticoid activity and is well tolerated with long-term use. The drug has an inhibitory effect on the release of mediators of the inflammatory response, reduces the number of mast cells and eosinophilic granulocytes. Budesonide reduces the release of toxic proteins from eosinophils, free radicals from macrophages and lymphokines from lymphocytes. It also reduces the binding of adhesion molecules to endothelial cells, thereby reducing the influx of leukocytes to the site of allergic inflammation. Budesonide increases the number of β-adrenergic receptors in smooth muscle. The drug inhibits the activity of phospholipase 2A, which leads to inhibition of the synthesis of prostaglandins, leukotrienes and Freund's complete adjuvant (PAF), which induce an inflammatory response. Budesonide also inhibits histamine synthesis, which leads to a decrease in histamine levels in mast cells.

Budesonide reduces the severity of symptoms in allergic rhinitis, suppresses the late and early phases of the allergic reaction and reduces inflammation in the upper respiratory tract. The therapeutic effect develops on average after 5-7 days.

After inhalation of 400 mcg of budesonide, Cmax in plasma is achieved within 0.7 hours and is 1 nmol/l. Only about 20% of the intranasally administered dose enters the systemic circulation.

Due to good distribution in tissues and binding to plasma proteins, the apparent Vd is 301 l.

Systemic bioavailability of budesonide is low because more than 90% of the absorbed drug is inactivated in the process of one-step metabolism in the liver. GCS metabolite activity does not exceed 1%.

T1/.8 hours. Excreted through the intestines in the form of metabolites - 10%, by the kidneys - 70%. Plasma concentrations of budesonide are increased in patients with liver disease.

Indications

  • prevention and treatment of seasonal and year-round allergic rhinitis;
  • vasomotor rhinitis;
  • nasal polyps.

Use during pregnancy and breastfeeding

The use of Budoster during pregnancy is allowed only if the expected benefit to the mother outweighs the possible risk to the fetus. If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped.

Contraindications

  • fungal, bacterial and viral infections of the respiratory tract;
  • active form of pulmonary tuberculosis;
  • children under 6 years of age;
  • hypersensitivity to budesonide or any other component of the drug.

With caution: recent surgical interventions in the nasal cavity, recent trauma to the nose, tuberculosis.

Side effects

Local reactions: burning sensation; formation of crusts on the nasal mucosa, dizziness. The risk of systemic effects should be taken into account, including suppression of adrenal function, growth retardation in children and adolescents, decreased bone mineral density, and symptoms of hypercortisolism. cataracts and glaucoma when budesonide is used in tall vines. Very often - irritation of the mucous membrane of the cavity of the suit. At the beginning of therapy, for a short time, rhinorrhea and excoriation may occur. Often - sneezing; sore and dry throat, pain in the nose and throat. Uncommon: nosebleeds; candidiasis of the mucous membrane of the pharynx and nasal cavity, in particular after prolonged therapy. Very rarely - atrophy of the mucous membrane, ulceration of the nasal mucosa, perforation of the nasal septum; anosmia.

Allergic reactions: rarely - allergic reactions (including dermatitis, rash, urticaria).

From the digestive system: rarely - nausea, vomiting, gastralgia.

From the cardiovascular system: very rarely - palpitations.

From the nervous system: rarely - myalgia, drowsiness, headache.

From the respiratory system: very rarely - cough, nasal congestion.

Interaction

Phenytoin, phenobarbital, rifampicin can reduce the effectiveness, methandienone, estrogens, ketoconazole and other powerful inhibitors of the CYP3A4 isoenzyme - increase it.

How to take, course of administration and dosage

For adults and children over 6 years of age, at the beginning of therapy, 100 mcg in each nasal passage 2 times a day. The usual maintenance dose is 50 mcg in each nostril 2 times a day or 100 mcg in each nostril once a day in the morning. The maintenance dose should be the lowest effective dose that eliminates symptoms of rhinitis. The maximum single dose is 200 mcg (100 mcg in each nostril), the maximum daily dose is 1 mg for no more than 3 months.

For the full therapeutic effect of the drug Budoster, regular and correct use is required.

If a dose of the vine is missed, it should be taken as soon as possible, but at least 1 hour before taking the next dose.

Children use the drug under the guidance of adults.

Overdose

Symptoms (in case of chronic overdose): acne, Cushing's syndrome, dysmenorrhea.

Treatment: gradual withdrawal of the drug.

Special instructions

The use of budesonide nasal spray is not recommended in patients with respiratory tract infections.

Patients should be informed that the effect of budesonide nasal spray is achieved on average after 5-7 days.

If after three months of treatment the symptoms of the disease do not decrease, the drug should be discontinued.

When switching from treatment with systemic glucocorticosteroids to GCS for local use, there is a risk of developing adrenal insufficiency, and therefore, caution is required during the period of restoration of the function of the hypothalamic-hyophyseal-adrenal system. The drug should be discontinued by gradually reducing the dose until the function of the hypothalamic-pituitary-adrenal system is normalized. During the dose reduction phase, some patients may experience symptoms of corticosteroid withdrawal, such as muscle and/or joint pain, apathy, and depression. If such symptoms are detected, a temporary increase in the dose of systemic corticosteroids may be required, and subsequently further withdrawal at a slower pace.

To achieve a therapeutic effect for allergic rhinitis, regular administration of the drug is required.

It is recommended to monitor the growth of children receiving long-term treatment with nasal corticosteroids. The child's growth rate slows down, the dose of nasal spray should be reduced.

Since corticosteroids slow down wound healing, caution should be exercised when prescribing Budoster to patients who have recently undergone trauma or surgery in the nasal area.

Avoid getting budesonide nasal spray in your eyes.

During long-term drug therapy, it is necessary to assess the condition of the nasal mucosa.

With long-term use of GCS for nasal administration in children, it is recommended to carry out dynamic growth monitoring. If growth slows, the pediatrician should reconsider the method of use of the drug in order to reduce the dose and switch to the minimum therapeutic dose at which control of the symptoms of the disease is possible.

Impact on the ability to drive vehicles and operate machinery

Budoster does not affect the ability to drive a car or operate machinery.

Release form

Dosed nasal spray

Storage conditions

Best before date

Brand

Conditions for dispensing from pharmacies

and health products

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  • Budoster, nasal spray 100 mcg/dose, 10 ml, Mifarm

License: No. LO814 dated August 8, 2016, OGRN: 1988

Source: http://www.eapteka.ru/goods/id227698/

Budoster spray called. 100mcg/dose 10ml

Delivery information Budoster spray called. 100mcg/dose 10ml

Pickup from a pharmacy in Moscow is free today, March 22.

Buy dosed nasal spray Budoster, 10 ml bottle, price 612 rub. in Moscow, St. Petersburg and other cities of Russia.

Online pharmacy "A-MEGA" is:

  • Convenient search for medications and fast order processing time;
  • The order is stored at the point for 3 days from the moment of arrival at the pharmacy;
  • Discounts and promotions on medicines every day.

You can order Budoster nasal spray, 10 ml bottle, with free delivery to your convenient A-MEGA pharmacy. Information about the operating hours of each pharmacy can be found on the pharmacy map.

pharmachologic effect

Budoster is a GCS for intranasal use. It has a pronounced anti-inflammatory and antiallergic effect. When used in therapeutic doses, it has virtually no resorptive effect. It does not have mineralocorticoid activity and is well tolerated with long-term use. The drug has an inhibitory effect on the release of mediators of the inflammatory response, reduces the number of mast cells and eosinophilic granulocytes. Budesonide reduces the release of toxic proteins from eosinophils, free radicals from macrophages and lymphokines from lymphocytes. It also reduces the binding of adhesion molecules to endothelial cells, thereby reducing the influx of leukocytes to the site of allergic inflammation. Budesonide increases the number of β-adrenergic receptors in smooth muscle. The drug inhibits the activity of phospholipase 2A, which leads to inhibition of the synthesis of prostaglandins, leukotrienes and Freund's complete adjuvant (PAF), which induce an inflammatory response. Budesonide also inhibits histamine synthesis, which leads to a decrease in histamine levels in mast cells.

Budesonide reduces the severity of symptoms in allergic rhinitis, suppresses the late and early phases of the allergic reaction and reduces inflammation in the upper respiratory tract. The therapeutic effect develops on average after 5-7 days.

After inhalation of 400 mcg of budesonide, Cmax in plasma is achieved within 0.7 hours and is 1 nmol/l. Only about 20% of the intranasally administered dose enters the systemic circulation.

Due to good distribution in tissues and binding to plasma proteins, the apparent Vd is 301 l.

Systemic bioavailability of budesonide is low because more than 90% of the absorbed drug is inactivated in the process of one-step metabolism in the liver. GCS metabolite activity does not exceed 1%.

T1/.8 hours. Excreted through the intestines in the form of metabolites - 10%, by the kidneys - 70%. Plasma concentrations of budesonide are increased in patients with liver disease.

Indications for use of the drug

  • prevention and treatment of seasonal and year-round allergic rhinitis;
  • vasomotor rhinitis;
  • nasal polyps.

Recommendations for use

For adults and children over 6 years of age, at the beginning of therapy, 100 mcg in each nasal passage 2 times a day. The usual maintenance dose is 50 mcg in each nostril 2 times a day or 100 mcg in each nostril once a day in the morning. The maintenance dose should be the lowest effective dose that eliminates symptoms of rhinitis. The maximum single dose is 200 mcg (100 mcg in each nostril), the maximum daily dose is 1 mg for no more than 3 months.

For the full therapeutic effect of the drug Budoster, regular and correct use is required.

If a dose of the vine is missed, it should be taken as soon as possible, but at least 1 hour before taking the next dose.

Children use the drug under the guidance of adults.

Side effect

Local reactions: burning sensation; formation of crusts on the nasal mucosa, dizziness. The risk of systemic effects should be taken into account, including suppression of adrenal function, growth retardation in children and adolescents, decreased bone mineral density, and symptoms of hypercortisolism. cataracts and glaucoma when budesonide is used in tall vines. Very often - irritation of the mucous membrane of the cavity of the suit. At the beginning of therapy, for a short time, rhinorrhea and excoriation may occur. Often - sneezing; sore and dry throat, pain in the nose and throat. Uncommon: nosebleeds; candidiasis of the mucous membrane of the pharynx and nasal cavity, in particular after prolonged therapy. Very rarely - atrophy of the mucous membrane, ulceration of the nasal mucosa, perforation of the nasal septum; anosmia.

Allergic reactions: rarely - allergic reactions (including dermatitis, rash, urticaria).

From the digestive system: rarely - nausea, vomiting, gastralgia.

From the cardiovascular system: very rarely - palpitations.

From the nervous system: rarely - myalgia, drowsiness, headache.

From the respiratory system: very rarely - cough, nasal congestion.

Contraindications

  • fungal, bacterial and viral infections of the respiratory tract;
  • active form of pulmonary tuberculosis;
  • children under 6 years of age;
  • hypersensitivity to budesonide or any other component of the drug.

With caution: recent surgical interventions in the nasal cavity, recent trauma to the nose, tuberculosis.

special instructions

The use of budesonide nasal spray is not recommended in patients with respiratory tract infections.

Patients should be informed that the effect of budesonide nasal spray is achieved on average after 5-7 days.

If after three months of treatment the symptoms of the disease do not decrease, the drug should be discontinued.

When switching from treatment with systemic glucocorticosteroids to GCS for local use, there is a risk of developing adrenal insufficiency, and therefore, caution is required during the period of restoration of the function of the hypothalamic-hyophyseal-adrenal system. The drug should be discontinued by gradually reducing the dose until the function of the hypothalamic-pituitary-adrenal system is normalized. During the dose reduction phase, some patients may experience symptoms of corticosteroid withdrawal, such as muscle and/or joint pain, apathy, and depression. If such symptoms are detected, a temporary increase in the dose of systemic corticosteroids may be required, and subsequently further withdrawal at a slower pace.

To achieve a therapeutic effect for allergic rhinitis, regular administration of the drug is required.

It is recommended to monitor the growth of children receiving long-term treatment with nasal corticosteroids. The child's growth rate slows down, the dose of nasal spray should be reduced.

Since corticosteroids slow down wound healing, caution should be exercised when prescribing Budoster to patients who have recently undergone trauma or surgery in the nasal area.

Avoid getting budesonide nasal spray in your eyes.

During long-term drug therapy, it is necessary to assess the condition of the nasal mucosa.

With long-term use of GCS for nasal administration in children, it is recommended to carry out dynamic growth monitoring. If growth slows, the pediatrician should reconsider the method of use of the drug in order to reduce the dose and switch to the minimum therapeutic dose at which control of the symptoms of the disease is possible.

Impact on the ability to drive vehicles and operate machinery

Budoster does not affect the ability to drive a car or operate machinery.

Overdose

Symptoms (in case of chronic overdose): acne, Cushing's syndrome, dysmenorrhea.

Treatment: gradual withdrawal of the drug.

Drug interactions

Phenytoin, phenobarbital, rifampicin can reduce the effectiveness, methandienone, estrogens, ketoconazole and other powerful inhibitors of the CYP3A4 isoenzyme - increase it.

Compound

Active substance: budesonide 100 mcg.

Excipients: dextrose, Avicel (microcrystalline cellulose and sodium carmellose in a ratio of 9:1), potassium sorbate, polysorbate 80, disodium edetate, hydrochloric acid to pH 4.5, purified water.

Use during pregnancy and breastfeeding

The use of Budoster during pregnancy is allowed only if the expected benefit to the mother outweighs the possible risk to the fetus. If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped.

Storage conditions and periods

Store at a temperature not exceeding 25°C. Do not freeze.

Shelf life: 2 years.

Conditions for dispensing from pharmacies

Single reference service for pharmacies

(daily from 08:00 to 20:00 Moscow time)

© 2018 A-MEGA pharmacy All rights reserved

Prices in pharmacies differ from the prices indicated on the website. Opening hours of the online pharmacy: orders are processed on weekdays from 9:00 to 18:00. If you place an order after 18:00, the order will be processed the next day. Orders on Saturday and Sunday are not processed and are postponed to Monday.

Online orders are not subject to promotions: “Happy Hours”, “A-Mega Wednesday”, “Thank you from Sberbank” discount coupons.

Source: http://www.aptekamega.ru/lekarstva_i_bad/dyhatelnaya_sistema/tsb/

Budoster nasal spray 100 mcg/dose, 10 ml

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Budoster nasal spray 100 mcg/dose, 10 ml, description:

Release form

Dosed nasal spray

Analogs by release form

Package

pharmachologic effect

Budoster is a GCS for intranasal use. It has a pronounced anti-inflammatory and antiallergic effect. When used in therapeutic doses, it has virtually no resorptive effect. It does not have mineralocorticoid activity and is well tolerated with long-term use. The drug has an inhibitory effect on the release of mediators of the inflammatory response, reduces the number of mast cells and eosinophilic granulocytes. Budesonide reduces the release of toxic proteins from eosinophils, free radicals from macrophages and lymphokines from lymphocytes. It also reduces the binding of adhesion molecules to endothelial cells, thereby reducing the influx of leukocytes to the site of allergic inflammation. Budesonide increases the number of β-adrenergic receptors in smooth muscle. The drug inhibits the activity of phospholipase 2A, which leads to inhibition of the synthesis of prostaglandins, leukotrienes and Freund's complete adjuvant (PAF), which induce an inflammatory response. Budesonide also inhibits histamine synthesis, which leads to a decrease in histamine levels in mast cells.

Budesonide reduces the severity of symptoms in allergic rhinitis, suppresses the late and early phases of the allergic reaction and reduces inflammation in the upper respiratory tract. The therapeutic effect develops on average after 5-7 days.

After inhalation of 400 mcg of budesonide, Cmax in plasma is achieved within 0.7 hours and is 1 nmol/l. Only about 20% of the intranasally administered dose enters the systemic circulation.

Due to good distribution in tissues and binding to plasma proteins, the apparent Vd is 301 l.

Systemic bioavailability of budesonide is low because more than 90% of the absorbed drug is inactivated in the process of one-step metabolism in the liver. GCS metabolite activity does not exceed 1%.

T1/.8 hours. Excreted through the intestines in the form of metabolites - 10%, by the kidneys - 70%. Plasma concentrations of budesonide are increased in patients with liver disease.

Analogues in composition

Indications

  • prevention and treatment of seasonal and year-round allergic rhinitis;
  • vasomotor rhinitis;
  • nasal polyps.

Contraindications

  • fungal, bacterial and viral infections of the respiratory tract;
  • active form of pulmonary tuberculosis;
  • children under 6 years of age;
  • hypersensitivity to budesonide or any other component of the drug.

With caution: recent surgical interventions in the nasal cavity, recent trauma to the nose, tuberculosis.

Use during pregnancy and breastfeeding

The use of Budoster during pregnancy is allowed only if the expected benefit to the mother outweighs the possible risk to the fetus. If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped.

special instructions

The use of budesonide nasal spray is not recommended in patients with respiratory tract infections.

Patients should be informed that the effect of budesonide nasal spray is achieved on average after 5-7 days.

If after three months of treatment the symptoms of the disease do not decrease, the drug should be discontinued.

When switching from treatment with systemic glucocorticosteroids to GCS for local use, there is a risk of developing adrenal insufficiency, and therefore, caution is required during the period of restoration of the function of the hypothalamic-hyophyseal-adrenal system. The drug should be discontinued by gradually reducing the dose until the function of the hypothalamic-pituitary-adrenal system is normalized. During the dose reduction phase, some patients may experience symptoms of corticosteroid withdrawal, such as muscle and/or joint pain, apathy, and depression. If such symptoms are detected, a temporary increase in the dose of systemic corticosteroids may be required, and subsequently further withdrawal at a slower pace.

To achieve a therapeutic effect for allergic rhinitis, regular administration of the drug is required.

It is recommended to monitor the growth of children receiving long-term treatment with nasal corticosteroids. The child's growth rate slows down, the dose of nasal spray should be reduced.

Since corticosteroids slow down wound healing, caution should be exercised when prescribing Budoster to patients who have recently undergone trauma or surgery in the nasal area.

Avoid getting budesonide nasal spray in your eyes.

During long-term drug therapy, it is necessary to assess the condition of the nasal mucosa.

With long-term use of GCS for nasal administration in children, it is recommended to carry out dynamic growth monitoring. If growth slows, the pediatrician should reconsider the method of use of the drug in order to reduce the dose and switch to the minimum therapeutic dose at which control of the symptoms of the disease is possible.

Impact on the ability to drive vehicles and operate machinery

Budoster does not affect the ability to drive a car or operate machinery.

Compound

1 dose contains:

active substance: budesonide 100 mcg

excipients: dextrose, Avicel (microcrystalline cellulose and sodium carmellose in a ratio of 9:1), potassium sorbate, polysorbate 80, disodium edetate, hydrochloric acid to pH 4.5, purified water.

Directions for use and doses

For adults and children over 6 years of age, at the beginning of therapy, 100 mcg in each nasal passage 2 times a day. The usual maintenance dose is 50 mcg in each nostril 2 times a day or 100 mcg in each nostril once a day in the morning. The maintenance dose should be the lowest effective dose that eliminates symptoms of rhinitis. The maximum single dose is 200 mcg (100 mcg in each nostril), the maximum daily dose is 1 mg for no more than 3 months.

For the full therapeutic effect of the drug Budoster, regular and correct use is required.

If a dose of the vine is missed, it should be taken as soon as possible, but at least 1 hour before taking the next dose.

Children use the drug under the guidance of adults.

Side effects

Local reactions: burning sensation; formation of crusts on the nasal mucosa, dizziness. The risk of systemic effects should be taken into account, including suppression of adrenal function, growth retardation in children and adolescents, decreased bone mineral density, and symptoms of hypercortisolism. cataracts and glaucoma when budesonide is used in tall vines. Very often - irritation of the mucous membrane of the cavity of the suit. At the beginning of therapy, for a short time, rhinorrhea and excoriation may occur. Often - sneezing; sore and dry throat, pain in the nose and throat. Uncommon: nosebleeds; candidiasis of the mucous membrane of the pharynx and nasal cavity, in particular after prolonged therapy. Very rarely - atrophy of the mucous membrane, ulceration of the nasal mucosa, perforation of the nasal septum; anosmia.

Allergic reactions: rarely - allergic reactions (including dermatitis, rash, urticaria).

From the digestive system: rarely - nausea, vomiting, gastralgia.

From the cardiovascular system: very rarely - palpitations.

From the nervous system: rarely - myalgia, drowsiness, headache.

From the respiratory system: very rarely - cough, nasal congestion.

Drug interactions

Phenytoin, phenobarbital, rifampicin can reduce the effectiveness, methandienone, estrogens, ketoconazole and other powerful inhibitors of the CYP3A4 isoenzyme - increase it.

Check the interaction of other drugs with Budoster

The drugs you have chosen

Overdose

Symptoms (in case of chronic overdose): acne, Cushing's syndrome, dysmenorrhea.

Treatment: gradual withdrawal of the drug.

Storage conditions

Store at a temperature not exceeding 25°C. Do not freeze.

Best before date

Possible product names

  • Русский
  • Budoster 100mcg/dose 10ml nasal spray
  • Budoster sp. called dosage 100 mcg/dose vial. 10ml
  • Budoster nasal spray. dosage fl. 100mcg/dose 10ml Italy
  • Budoster spray nasal doses 100mcg/dose 10ml fl doses ind pack
  • Budoster nasal spray 100 mcg/dose, 10 ml

Certificates (2)

Reviews of Budoster nasal spray 100 mcg/dose, 10 ml

** Delivery is carried out only for the preferential category of citizens on the basis of Art. 2 of the Federal Law of the Russian Federation of 01/09/1997 N 5-FZ “On the provision of social guarantees to heroes of socialist labor and full holders of the Order of Labor Glory” (as amended on 07/02/2013) and Article 1.1 of the RF Law of 01/15/1993 N “On the status of Heroes Soviet Union, Heroes of the Russian Federation and full holders of the Order of Glory." All orders are placed in a pharmacy (licensed) and collected by qualified pharmacists.

Source: http://www.piluli.ru/product631260/product_info.html

BUDOSTER 100MCG/DOSE 10ML NASAL SPRAY

different from pictured

Similar products

DOCTOR FALK PHARMA

Budoster instructions for use

Dosage form

Nasal spray dosed in the form of a white or almost white homogeneous suspension.

Compound

pharmachologic effect

GKS. When used inhalation, it has anti-inflammatory, anti-allergic and anti-exudative effects, which leads to a reduction in bronchial obstruction. The mechanism of action is to inhibit the release of inflammatory and allergic mediators, as well as to reduce the reactivity of the respiratory tract to their action. During the treatment, respiratory function improves, the severity and frequency of shortness of breath, attacks of suffocation, and cough are significantly reduced. The maximum clinical effect develops after 1-2 weeks of therapy.

Pharmacokinetics

Side effects

Local reactions: burning sensation; formation of crusts on the nasal mucosa, dizziness. The risk of systemic effects should be taken into account, including suppression of adrenal function, growth retardation in children and adolescents, decreased bone mineral density, and symptoms of hypercortisolism. cataracts and glaucoma when budesonide is used in tall vines. Very often - irritation of the mucous membrane of the cavity of the suit. At the beginning of therapy, for a short time, rhinorrhea and excoriation may occur. Often - sneezing; sore and dry throat, pain in the nose and throat. Uncommon: nosebleeds; candidiasis of the mucous membrane of the pharynx and nasal cavity, in particular after prolonged therapy. Very rarely - atrophy of the mucous membrane, ulceration of the nasal mucosa, perforation of the nasal septum; anosmia.

Selling Features

Special conditions

The use of budesonide nasal spray is not recommended in patients with respiratory tract infections.

Indications

— prevention and treatment of seasonal and year-round allergic rhinitis;

Contraindications

- fungal, bacterial and viral infections of the respiratory tract;

Drug interactions

Phenytoin, phenobarbital, rifampicin can reduce the effectiveness, methandienone, estrogens, ketoconazole and other powerful inhibitors of the CYP3A4 isoenzyme - increase it.

  • You can buy Budoster 100mcg/dose 10ml nasal spray in Moscow at a pharmacy convenient for you by placing an order on Apteka.RU.
  • We have a low price for Budoster 100mcg/dose 10ml nasal spray in Moscow.

You can see the delivery points closest to you in Moscow here.

Source: http://apteka.ru/catalog/budoster-100mkg-doza-10ml-sprey-nazal-_52dd4c053747a/

Budoster spray price

mcg per day;

mcg per day.

Features of application:
  • It is necessary to rinse your mouth after using the drug to avoid the development of candidiasis of the oral mucosa;

Side effects

  • Русский
  • Respiratory system: throat irritation, sneezing, cough, paradoxical bronchospasm, dry mucous membranes, oral candidiasis;

Contraindications

  • Русский
  • Pulmonary tuberculosis, fungal, bacterial or viral respiratory tract infections;
Use with caution:
  • Liver failure;

During pregnancy and lactation

Interaction with other drugs

Simultaneous use of Budoster with:
  • Phenobarbital, Rifampicin or Phenytoin: enhancing the effectiveness of the drug;

Overdose

Symptoms:
  • Metabolic processes: hypercortisolism.

Specific antidote: not identified.

Treatment of overdose with Budoster:
  • Reducing the dosage or completely stopping the drug;

Hemodialysis: no data.

Release form

  • Русский
  • Dosed nasal spray, 50 mcg/1 dose or 100 mcg/1 dose - vial. 200 doses.

Storage conditions

  • Русский
  • A dry, dark place away from heat sources and children's access.

Recommended storage temperature for Budoster

- no higher than 25 degrees.

Recommended storage period:

  • New cartridge - within 3 years;

Compound

1 dose of spray:
  • budesonide - 50 or 100 mcg;

Conditions for dispensing from pharmacies

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Price for "Budoster" in Russian pharmacies

It may not be accurate or out of date and should not be used for diagnosis or treatment under any circumstances! For both, you should consult your doctor.

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Source: http://socialnye-apteki.ru/filial/catalog/budoster

Budoster

Budoster is a glucocorticosteroid for topical use.

The active substance is Budesonide.

ATX group R.03.BA02.

Use this medicine with caution:

The drug is not recommended for use:

Dispensed by prescription.

Budoster price, reviews and availability

Budoster Instructions for use

Group

Drugs with glucocorticosteroid activity.

Composition of Budoster

Manufacturers

Mifarm S.p.A. (Italy)

pharmachologic effect

Glucocorticosteroid for intranasal use.

It has a pronounced anti-inflammatory and antiallergic effect.

When used in therapeutic doses, it has virtually no resorptive effect.

It does not have mineralocorticoid activity and is well tolerated with long-term use.

The drug has an inhibitory effect on the release of mediators of the inflammatory response, reduces the number of mast cells and eosinophilic granulocytes.

Budesonide reduces the release of toxic proteins from eosinophils, free radicals from macrophages and lymphokines from lymphocytes.

It also reduces the binding of adhesion molecules to endothelial cells, thereby reducing the influx of leukocytes to the site of allergic inflammation.

Budesonide increases the number of beta-adrenergic receptors in smooth muscle.

The drug inhibits the activity of phospholipase 2A, which leads to inhibition of the synthesis of prostaglandins, leukotrienes and Freund's complete adjuvant (PAF), which induce an inflammatory response.

Budesonide also inhibits histamine synthesis, which leads to a decrease in histamine levels in mast cells.

Budesonide reduces the severity of symptoms in allergic rhinitis, suppresses the late and early phases of the allergic reaction and reduces inflammation in the upper respiratory tract.

The therapeutic effect develops on average after 5-7 days.

After inhalation of 400 mcg of budesonide, the maximum plasma concentration is reached within 0.7 hours and is 1 nmol/l.

Only about 20% of the intranasally administered dose enters the systemic circulation.

Due to good tissue distribution and binding to plasma proteins, the apparent volume of distribution (Vd) is 301 l.

Systemic bioavailability of budesonide is low because more than 90% of the absorbed drug is inactivated in the process of one-step metabolism in the liver.

Glucocorticosteroid activity of metabolites does not exceed 1%.

The half-life is 2-2.8 hours.

Excreted through the intestines in the form of metabolites - 10%, by the kidneys - 70%.

Plasma concentrations of budesonide are increased in patients with liver disease.

Side effects of Budoster

Burning sensation; formation of crusts on the nasal mucosa, dizziness.

The risk of systemic effects, including adrenal suppression, growth retardation in children and adolescents, decreased bone mineral density, symptoms of hypercortisolism, cataracts and glaucoma, should be considered when using budesonide in high doses.

  • irritation of the nasal mucosa.

At the beginning of therapy, for a short time, rhinorrhea and excoriation may occur.

  • sneeze;
  • sore and dry throat, pain in the nose and throat.
  • nose bleed;
  • candidiasis of the mucous membrane of the pharynx and nasal cavity, in particular after prolonged therapy.
  • atrophy of the mucous membrane, ulceration of the mucous membrane of the nasal cavity, perforation of the nasal septum;
  • anosmia.

From the digestive system.

From the cardiovascular system.

From the nervous system.

From the respiratory system.

Indications for use

Prevention and treatment of seasonal and year-round allergic rhinitis; vasomotor rhinitis; nasal polyps.

Contraindications Budoster

Fungal, bacterial and viral infections of the respiratory tract; active form of pulmonary tuberculosis; hypersensitivity to budesonide or any other component of the drug; children under 6 years of age.

Directions for use and dosage

For adults and children over 6 years of age, at the beginning of therapy, 100 mcg in each nasal passage 2 times a day.

The usual maintenance dose is 50 mcg in each nostril 2 times a day or 100 mcg in each nostril once a day in the morning.

The maintenance dose should be the lowest effective dose that eliminates symptoms of rhinitis.

The maximum single dose is 200 mcg (100 mcg in each nostril), the maximum daily dose is mcg for no more than 3 months.

For the full therapeutic effect of the drug, regular and correct use is required.

If a dose is missed, it should be taken as soon as possible, but at least 1 hour before the next dose.

Children use the drug under the guidance of adults.

Overdose

Symptoms (in case of chronic overdose):

Interaction

Phenytoin, phenobarbital, rifampicin can reduce the effectiveness, methandienone, estrogens, ketoconazole and other powerful inhibitors of the CYP3A4 isoenzyme - increase it.

special instructions

  • recent surgical interventions in the nasal cavity,
  • recent nose injury,
  • tuberculosis.

Use during pregnancy and lactation.

The use of the drug during pregnancy is allowed only if the expected benefit to the mother outweighs the possible risk to the fetus.

If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped.

The use of the nasal spray is not recommended in patients with respiratory tract infections.

Patients should be informed that the effect of budesonide nasal spray is achieved on average after 5-7 days.

If after three months of treatment the symptoms of the disease do not decrease, the drug should be discontinued.

When switching from treatment with systemic glucocorticosteroids to glucocorticosteroids for local use, there is a risk of developing adrenal insufficiency, and therefore, caution is required during the period of restoration of the function of the hypothalamic-pituitary-adrenal system.

The drug should be discontinued by gradually reducing the dose until the function of the hypothalamic-pituitary-adrenal system is normalized.

During the dose reduction phase, some patients may experience symptoms of corticosteroid withdrawal, such as muscle and/or joint pain, apathy, and depression.

If such symptoms are detected, a temporary increase in the dose of systemic glucocorticosteroids may be required, and subsequently further withdrawal at a slower pace.

To achieve a therapeutic effect for allergic rhinitis, regular administration of the drug is required.

It is recommended to monitor the growth of children receiving long-term treatment with nasal corticosteroids.

If the child's growth slows down, the dose of the nasal spray should be reduced.

Since glucocorticosteroids slow down wound healing, caution should be exercised when prescribing the drug to patients who have recently undergone trauma or surgery in the nasal area.

Avoid getting budesonide nasal spray in your eyes.

The drug does not affect the ability to drive a car or operate machinery.

During long-term drug therapy, it is necessary to assess the condition of the nasal mucosa.

With long-term use of glucocorticosteroids for nasal administration in children, dynamic growth monitoring is recommended.

If growth slows, the pediatrician should reconsider the method of use of the drug in order to reduce the dose and switch to the minimum therapeutic dose at which control of the symptoms of the disease is possible.

Storage conditions

Store out of the reach of children at a temperature not exceeding 25 C.

Leave procedure

Dispensed by prescription.

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Source: http://elixir.farm/lekarstva/budoster/