Augmentin how to take

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Instructions for use Augmentin tablets and suspensions + reviews

Augmentin is a combined antimicrobial drug that contains amoxicillin, which has a bactericidal effect, and clavulanic acid (clavulanate), which inhibits a group of bacterial enzymes - β-lactamase.

Table of contents:

The latter hydrolyze penicillin and cephalosporin antibiotics, as a result of which the latter do not have time to demonstrate their antimicrobial effect. Augmentin is a drug with an extended spectrum of activity.

Aerobes and anaerobes are sensitive to Augmentin. The antibiotic has a bacteriolytic effect, i.e. destroys pathogenic microorganisms. Amoxicillin itself degrades in the presence of β-lactamases, so it is ineffective in eradicating microbial cultures that synthesize these enzymes. Clavulanic acid, which is part of the drug, imparts stability to semisynthetic penicillin, thereby expanding the spectrum of its activity.

Augmentin - instructions for use of tablets 1000, 500 and 125 mg

The tablets are not crushed or chewed, but are swallowed whole and washed down with clean non-carbonated water (100 milliliters is enough). As for the suspension, the required amount of the finished solution is measured using a measuring cap or a syringe on which divisions are applied. The syringe or measuring cup is thoroughly washed after use.

Augmentin in liquid form (suspension) is preferably taken before meals, which significantly improves absorption. In addition, this will reduce the likelihood of unwanted reactions from the esophagus, stomach and intestines.

The suspension is used exclusively orally. 0.06 liters of boiled water at room temperature is poured into a container with powder. Close the bottle tightly with a lid and shake thoroughly until a homogeneous mass is obtained.

The powder will dissolve completely if left for a few minutes. Next, the procedure is repeated, adding water up to the mark on the bottle. The shelf life of the prepared solution is a week; it is stored in the general chamber of the refrigerator. The technology for preparing the suspension is described in detail in the insert included in the package.

All dosage forms are taken at the same intervals. For example, if the doctor prescribed taking an antibiotic twice a day, this means that Augmentin should enter the body every 12 hours.

The minimum course of treatment with Augmentin is five days. After diagnosis and in the absence of repeated examination, therapy should not last more than 14 days. If, upon review of the clinical situation, a slow but positive dynamics of the recovery process was revealed, then the course of treatment is continued. The duration of the course must be agreed with the attending physician.

Experts often resort to stepwise antibacterial therapy, which involves the 2-stage use of antibiotic drugs: for example, switching from parenteral to oral administration. In the case of Augmentin, the injection method is first practiced, and then tablets are used.

Pharmacological parameters

Augmentin causes the death of facultative flora and blocks the biosynthesis of the cell membrane, which performs structural, protective and transport functions. Amoxicillin, coupled with clavulanic acid, enhances the bactericidal activity of segmented neutrophils, which play a very important role in protecting the body from infections of bacterial and fungal etiology. Clavulanic acid stimulates the adhesion and motor response of neutrophils (leukocytes) to a chemical stimulus.

Pharmacology of amoxicillin

Amoxicillin is destroyed by penicillinase. The antibiotic is resistant to acidic environments. Its target is the bacterial enzyme glycopeptide transpeptidase. The antimicrobial agent suppresses the synthesis of murein, which performs the antigenic and mechanical functions of osmotic cell protection.

Pharmacology of clavulanic acid

Clavulanate has its own antimicrobial activity. Pseudomonas aeruginosa and Enterococcus are sensitive to the inhibitor (minimal activity); Haemophilus influenzae and Enterobacteriaceae (moderate activity); Bacteroides, Moraxella, Staphylococcus, Streptococcus, Neisseria gonorrhoeae, Chlamydia trachomatis and Legionella (high activity). Like other β-lactam antibiotics, clavulanic acid interacts with penicillin-binding proteins of gram+ and gram-pathogens and promotes the dissolution of the cell membrane.

Pharmacokinetic parameters

Pharmacokinetic data were obtained in experimental and laboratory studies in volunteers after administration on an empty stomach.

Speed ​​of achieving effective drug concentration in plasma

The drug is rapidly and completely absorbed from the gastrointestinal tract. The absorption of Augmentin's active ingredients is optimal when taken before meals. The time to reach maximum concentration is 3/4 hours.

Distribution of lek. means in the body

Therapeutic concentrations of amoxicillin and clavulanate are formed in the organs of the chest and abdominal cavity, adipose tissue, bones, muscles, bile, serous-purulent discharge and fluids: pleural, produced by the pleura, synovial, filling the joints, peritoneal, responsible for moisturizing the abdominal wall, and tissue contained in the pericellular spaces. The degree of binding to plasma proteins is low (no more than thirty percent for both substances).

Metabolism and Elimination

The antibiotic is eliminated by the kidneys (glomerular filtration and tubular secretion). After a single oral dose, both substances are eliminated from the body within six hours. The half-life depends on the dose, the average is one hour.

Composition of Augmentin

The main components of the antibiotic are Amoxicillin (amoxicillin) and Clavulanic acid (clavulanic acid), the physiological effects of which are associated with the medicinal properties of Augmentin. Contains xanthan gum (stabilizer, whitish powder, odorless and tasteless), L-Aspartyl-L-phenylalanine (sweetener), butanedioic acid (colorless crystals, soluble in water and ethanol) and food flavors (berry and citrus flavors) .

Recipe in Latin

Rp: Augmentini 0.875.

D. td N. 20 in tab.

S. 1 tablet 2 times a day

Augmentin release form

The pharmaceutical industry produces Augmentin in the form of:

  1. White powder with a specific odor. When water is added, a suspension of a similar color is formed. After settling in the container, a sediment gradually forms.
  2. Tablet form containing 250 milligrams of Amoxycillinum and 125 milligrams of clavulanic acid. The tablets are film-coated, with the name “Augmentin” engraved on the surface in Latin.
  3. Tablet form containing 500 milligrams of Amoxycillinum and 125 milligrams of clavulanic acid. On one side of the table. The letters "AC" are printed.
  4. Tablet form containing 875 milligrams of Amoxycillinum and 125 milligrams of clavulanic acid. The letters "A" and "C" are die-cut on the top and bottom sides. The pharmaceutical corporation Glaxosmithkline does not supply Augmentin syrup for children to the pharmaceutical market.

Photo of Augmentin tablets

What does Augmentin help with?

Augmentin is active against pathogens susceptible to it. The combination medicine is prescribed for infections caused by microorganisms that are resistant to the antibiotic included in the composition.

Taking Augmentin helps eradicate the following microbial cultures:

  • gram+ aerobes that require free molecular oxygen for energy synthesis processes (including strains synthesizing β-lactamases): Staphylococcus aureus, epidermal st., streptococci, pneumococcus, fecal enterococcus, corynebacteria, listeria;
  • gram-aerobes: Escherichia coli, Proteus mirabilis;
  • gram+ anaerobes that obtain energy in the absence of oxygen: clostridia, peptostreptococci, peptococci, Proteus, Klebsiella, Salmonella, Shigella, Bordet-Gengou bacterium, Yersinia enterocolitica, Campylobacter jeuni
  • and other gram+ pathogens: bacteroides, including bacteroides fragilis.

Indications for use of Augmentin

The combination of amoxicillin with clavulanate is indicated for the treatment of diseases of bacterial origin in the following localizations:

  • ENT organs: tonsillitis, sinusitis, otitis media (including relapses). The causative agents are streptococcus pyogenes, pneumococcus, and influenza bacillus.
  • lower parts of the respiratory system: exacerbation of bronchitis, occurring in a chronic form, pyothorax, abscess, bronchogenic and lobar pneumonia, developing when the body is invaded by pneumococci and influenza bacillus.
  • urinary system and genital organs: cystitis, pelvioperitonitis, endometritis, urethritis, pyelonephritis and diseases of the female organs of the reproductive system: vaginitis, salpingoophoritis, inflammatory adnextumor (enterobacteriaceae, Escherichia coli, saprophytic staphylococcus, enterococci, gonococcus causing gonorrhea).
  • dermis and soft tissues, which include muscles, tendons, synovial membranes, adipose tissue, fibrous connective tissue: inflammation of the subcutaneous tissue, purulent inflammation of the tissues, furunculosis, panniculitis (staphylococcus aureus, st. pyogenic, bacteroides).
  • bone tissue: purulent-necrotic processes developing in the bone and bone marrow (staphylococcus aureus). Augmentin is prescribed if long-term treatment is necessary.
  • oral cavity: periodontal inflammation,

maxillary sinusitis, severe dentoalveolar abscesses.

Indications for use include septic abortion, obstetric and intra-abdominal sepsis, septicemia, peritonitis, cholecystitis.

Who is Augmentin contraindicated for?

The antibiotic is not prescribed to patients with a history of hypersensitivity to amoxicillin, clavulanate, β-lactams and other components. The reasons for refusing therapy with this drug are:

  • phenylketonuria is a hereditary disease caused by a metabolic disorder of α-amino-β-phenylpropionic acid;
  • kidney pathologies and other severe dysfunctions, for example, low creatinine;
  • infancy up to three months (for suspension);
  • age up to twelve years and weight less than forty kilograms (for solid forms);
  • lymphoblastosis is benign, since the antibiotic can provoke the appearance of rashes, which will complicate the diagnosis;
  • previous episodes of Gospel disease.

Augmentin dosage for adults

Establishing a dosage regimen is the responsibility of the attending physician. When selecting a dosage, the doctor takes into account age, weight, the presence of diseases of the urinary system, the clinical condition of the patient, and individual characteristics.

Adults and children in puberty (adolescents from twelve years of age or with a body weight exceeding forty kg) should be prescribed eleven milliliters of a suspension at a dosage of 400 mg plus 57 mg, which is equivalent to one tablet containing 875 mg of amoxicillin.

Low doses of Augmentin are indicated for getting rid of skin infections and for recurrent inflammation of the tonsils. High doses are indispensable in the treatment of otitis, sinusitis, infections of bone and joint tissue.

For infants up to three months, due to the incompletely formed excretory function of the kidneys, the recommended dose is thirty milligrams per kg of body weight. As for premature infants, there is no reliable data on the dosage regimen.

Patients over sixty years of age do not require dosage adjustment. You should adhere to the recommendations that guide the treatment of young patients.

For persons with liver dysfunction, antibiotic therapy is prescribed with caution, while liver function testing is carried out on a regular basis.

For persons with renal failure, the dosage regimen is adjusted based on an assessment of creatinine clearance, which is the main quantitative indicator of the secretory organ.

Dosage of Augmentin for children in suspension 200 and 400 ml

In pediatric practice, Augmentin is prescribed to children in the form of a suspension.

How to correctly calculate the dosage of Augmentin suspension for children (200 mg, 400 mg)

Parents cannot always correctly determine the dosage regimen. For clarity, we will give an example of calculating the dosage for a girl whose therapist diagnosed inflammation of the bronchial mucosa. The child is one and a half years old and weighs ten kg.

Bronchitis leads to disruption of the normal functioning of a vital organ; if the disease occurs without respiratory failure, then the patient’s condition is classified as moderate-severe.

For moderate bronchitis, we take into account forty milligrams per kg. The girl weighs ten kg, so the single dosage is: forty * ten = four hundred milligrams. 400 mg of amoxicillin is contained in ten milliliters of a suspension of 200 mg plus 28.5 mg/5 ml or in 5 ml of 400 mg plus 57 mg/5 ml.

Augmentin during pregnancy and breastfeeding

During animal tests conducted in the laboratory, it was revealed that both components penetrate the utero-placental barrier and are determined in minimal quantities in mother’s milk. However, antibiotic therapy with Augmentin is not a teratogenic factor, because The drug does not disrupt the embryonic development of the fetus. Augmentin is used during pregnancy both orally and parenterally.

In isolated cases of women with a violation of the integrity of the membranes of the fetal bladder before the onset of labor, it was found that preventive therapy with this medication may be associated with inflammation of the small and large intestines (necrotizing enterocolitis) in the newborn. Augmentin should be taken only for vital indications.

Treatment with the antibiotic Augmentin has only a minor effect on breastfeeding (BF), with the exception of the risk of sensitization.

A woman carrying a child should take into account that almost all antibiotics are poorly tolerated by the body. This pharmacological group has many contraindications and adverse reactions. For example, during treatment, patients often experience candidiasis.

Antibiotic drugs are strong allergens that during pregnancy can trigger skin rashes, asthmatic attacks and even anaphylactic reactions that threaten the life and health of the mother. In addition, Augmentin inhibits the enzymatic activity of the flora of the digestive tract, which leads to dysbiosis. A pregnant woman may experience constipation, diarrhea, abdominal pain and increased gas production.

Penicillin affects the bone marrow, which causes disruption of hematopoiesis. Aplastic anemia tops the list of serious complications.

Taking Augmentin during pregnancy is possible, but only if the therapeutic effect for the expectant mother outweighs the potential risk to the fetus. In the first trimester, it is advisable to find alternative methods of treatment or select the safest antibiotics possible.

Side effects and effects when taking Augmentin

Adverse drug reactions are listed by frequency of occurrence:

  • candidiasis caused by yeast-like fungi of the genus Candida. Taking antibiotics leads to an increase in the population of this yeast. Yeast-like fungi Candida are part of the normal microflora of the oral cavity, vagina and colon;
  • leukopenia, in which patients experience general weakness, rapid pulse, and low-grade fever;
  • thrombocytopenia, accompanied by increased bleeding, problems stopping bleeding, frequent nosebleeds;
  • agranulocytosis, the clinical picture of which manifests itself in the form of damage to the body by infections due to a decrease in the effectiveness of the immune response;
  • high physical activity and excitability of a person;
  • stool disorders (frequent bowel movements);
  • nausea that occurs when taking high doses;
  • antibiotic-associated colitis;
  • disease black villous tongue, characterized by hyperplasia of the filiform papillae of the tongue and their keratinization;
  • darkening of tooth enamel. Teeth will not change color if proper oral care is taken;
  • drug-induced hepatitis, because almost all antibiotics have hepatotoxicity;
  • increased bilirubin, which is signaled by increased fatigue, yellowness of the skin and mucous membranes;
  • high concentration of alkaline phosphatase. Patients complain of loss of appetite and pain in the right hypochondrium;
  • intrahepatic cholestasis, accompanied by a lack of access of bile to the intestine and impaired permeability of bile capillaries;
  • skin rashes diagnosed in patients with individual intolerance and concomitant diseases;
  • a symptomatic form of polymorphic erythema of toxic-allergic origin. In the first stages, clearly defined edematous papules of a pinkish hue appear;

Side effects from the liver are more common in males and elderly patients. The cause of such reactions is often prolonged treatment. In childhood, complications from the liver practically do not occur. Most often, side effects are reversible.

The above symptoms make themselves felt during therapy or some time after its completion. Structural and functional disorders of the liver pose a danger.

Augmentin and alcohol

It is a well-known fact that antibiotic therapy and alcohol are two incompatible concepts. However, controversy among practicing doctors on this issue still does not subside. Let us immediately make a reservation that ethyl alcohol does not affect the concentration of Augmentin in the blood and the therapeutic effect.

It is quite difficult to assess the compatibility and possibility of concurrent use of the antibiotic Augmentin and alcohol, but it is possible to study the effect of drugs on certain organs and systems. The liver suffers the most, as it receives a double blow, because it is the liver that neutralizes toxic substances, which include ethanol and some pharmacological groups.

Drinking alcoholic beverages during antibiotic treatment contributes to the development of kidney failure. Moreover, in this case, the age of the patient does not matter; such combinations are deadly for all age groups.

During alcoholic libations, there is a narrowing of blood vessels, which can affect the distribution and transportation of the antibiotic.

The load increases not only on the organs of the hepatobiliary system, but also on the digestive organs. A person who simultaneously takes ethanol and Augmentin runs the risk of becoming a patient in the gastroenterology department, because the risk of:

  • pancreatitis, to which dehydration of the body is added;
  • acute hepatitis. A person may feel unwell in the first hours after drinking alcohol;
  • erosion of the stomach and intestines. It is dangerous because the disease does not make itself felt for a long time;
  • peptic ulcer, manifested by internal bleeding. Alcohol together with Augmentin can initiate the entry of blood into the natural cavity of the body.

Analogues and generics

  • Amoxiclav Quiktab (from 360 to 600 rubles)
  • Amoxiclav (from 250 to 550 rubles) -
  • Arlet (from 230 to 560 rubles)
  • Augmentin SR (from 650 to 900 rubles);
  • Klamosar (from 370 to 530 rubles)
  • Honeyclave (from 210 to 310 rubles)
  • Panclave (from 220 to 520 rubles)
  • Ranklav (from 390 to 560 rubles)
  • Rapiklav (from 330 to 450 rubles)
  • Flemoklav Solutab (from 290 to 870 rubles)

Augmentin: reviews from doctors for children and adults

Doctors

Augmentin is inexpensive and suitable for treating adults and children. The disadvantages include the fact that the antibiotic is a perishable medicine, and its shelf life is only seven days. In exceptional cases, patients experience antibiotic-associated diarrhea. Protected penicillin copes well with respiratory infections. The suspension has a pleasant taste due to the addition of food additives and flavorings.

Augmentin is an original medicine, it fully meets safety standards, is produced in accordance with all quality standards, and goes through all stages of purification. The drug helps with systemic infections when the body is affected by several strains of bacteria. The drug is well tolerated. Clavulanic acid can inactivate a wider range of pathogens.

Patients rarely complain of complications, but some develop dyspeptic symptoms. Persons receiving Augmentin should not forget about fungal infections, which are a faithful companion to long-term antibiotic therapy.

Augmentin is suitable for all age groups. Indispensable in the treatment of infections of the ear, nose, and lower respiratory tract. A properly selected dosage regimen helps prevent the occurrence of adverse reactions. In adults, complications are extremely rare. It is more effective than unprotected penicillins, which are destroyed by bacterial enzymes.

Consumer Opinion

Reviews from patients taking tablets about the antibiotic Augmentin:

For sinusitis: “Augmentin helps well with inflammation of the lining of the maxillary sinus, especially if the therapy is supplemented with regular rinsing. The drug eliminates clinical symptoms such as headache, heaviness in the paranasal or frontal region, and rhinorrhea.”

For acute respiratory viral infections occurring together with infections of bacterial origin: “A five-day course of treatment with the drug did not give any result. There was discomfort in the legs, sleep disturbances, and at a follow-up appointment the attending physician diagnosed bronchial inflammation.”

For cystitis: “Augmentin is a good and effective remedy for this disease, however, allergic reactions, such as itchy skin, may occur during treatment. The antibiotic is clearly contraindicated in case of hypersensitivity of the body. Before use, you should thoroughly study the instructions to avoid a possible allergy to Augmentin.”

For otitis media: “The duration of treatment with Augmentin was a week, but recovery did not occur. The absence of positive dynamics was confirmed by the otolaryngologist. While taking the antibiotic, the condition only worsened: purulent discharge from the ear canal, shooting pains, high fever.”

For tonsillitis: “The therapeutic effect occurs in the shortest possible time, since the drug begins to act immediately. After about three days, the white coating on the tonsils disappears. However, the antibiotic is not selective and destroys obligate microflora in the intestine, which leads to the development of dysbiosis.”

Historical reference

In the antimicrobial agent, specialists from the pharmaceutical company Glaxosmithkline implemented the concept of “attacking, defending”: clavulanate irreversibly inhibits beta-lactamases, opening an unhindered path for amoxicillin to attack foreign agents. With the invention of Augmentin, the era of the Renaissance of penicillin antibiotics that had fallen into the background began.

The use of Augmentin in medical practice has an impressive evidence base: doctors have been prescribing the drug for thirty years. During this time, hundreds of experimental studies were conducted involving tens of thousands of volunteers. Today there are about a thousand publications containing data on its effectiveness.

Over such a long period of use (since the 80s of the 20th century) of the antibiotic, microbiologists have never identified strains that have acquired resistance to it. For example, data obtained as part of a large-scale European study, the Alexander Project (the project was named after Alexander (III) the Great, who, according to historians, died of pneumonia) provides evidence of its high antimicrobial activity.

The National Committee for Clinical and Laboratory Standards (NCCLS) recognized the uniqueness of Augmentin: from now on, all new antimicrobial drugs are compared with it. Today, the antibiotic is used in all developed countries of the world: England, the United States of America, France, etc.

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Suspension "Augmentin" for children: instructions for use

When choosing an antibiotic to treat any infection, preference is often given to drugs with a broad spectrum of antimicrobial action. One of them is Augmentin. For children, it is more convenient to give this medicine in liquid form. When is it prescribed to young children and how is the suspension prepared? Is the drug taken before or after meals? How long to treat a child? These and other questions interest every mother if her son or daughter has to take an antibiotic.

Release form

Augmentin, from which the suspension is prepared, is presented as a powder placed in a glass bottle. This powder has a white color and a characteristic odor, and after adding water it produces a white suspension, which separates during storage to form a white precipitate. The medicine is also available in injection form (it is intended for intravenous administration) and in coated tablets with different dosages (they can contain 250, 500 or 875 mg of antibiotic each).

Compound

Augmentin includes two active ingredients at once, thanks to which it has a wide range of effects on microorganisms:

  1. Amoxicillin. This antibiotic is presented in trihydrate form and is contained in 5 ml of the finished medicine at a dosage of 125 mg, 200 mg or 400 mg.
  2. Clavulanic acid. This compound is a potassium salt and the dosage of this acid is, depending on the dose of amoxicillin, 31.25 mg, 28.5 mg or 57 mg per 5 ml of suspension.

The ratio of these two components is represented by the proportion 4:1 and 7:1. Additionally, the bottle contains silicon dioxide, xanthan gum, hypromellose and succinic acid. For sweetness, aspartame is added to the preparation, and the smell of the suspension is provided by orange, raspberry and molasses flavors.

Operating principle

Amoxicillin in Augmentin has an antimicrobial effect on many types of microorganisms. It acts bactericidal, causing the death of bacteria due to inhibition of the synthesis of their cell walls. However, this antibiotic can be destroyed by beta-lactamases, so it cannot kill bacteria that produce such enzymes.

It is to prevent this destruction that clavulanic acid is present in the drug. It inactivates beta-lactamases, which makes even amoxicillin-resistant microbes sensitive to the suspension.

The drug is effective against:

  • Various types of staphylococci, including saprophytic and aureus.
  • Whooping cough sticks.
  • Various types of streptococci, including hemolytic, pyogenic and group B.
  • Nocardium.
  • Listeria.
  • Haemophilus influenzae.
  • Enterococci.
  • Helicobacter pylori.
  • Gonococcus.
  • Cholera vibrios.
  • Pasteurell.
  • Peptococci and peptostreptococci.
  • Moraxell.
  • Treponema pallidum.
  • Leptospira.
  • Borrelia.
  • Bacteroides.
  • Clostridium.
  • Fusobacterium.

The suspension may be powerless against E. coli, Proteus, Salmonella, Corynebacteria, Pneumococcus, Klebsiella and Shigella, so if infected with these microorganisms, it is recommended to first do a sensitivity test.

The drug is considered ineffective against infection with Citrobacter, Enterobacter, Morganella, Providence, Legionella, Hafnia, Pseudomonas, Yersinia, Chlamydia, Coxiella, Mycoplasma and Serracia. In addition, this medicine does not help with influenza, herpetic sore throat, ARVI, mononucleosis, chickenpox and other viral infections.

Indications

Augmentin in the form of a suspension is prescribed:

  • When bacteria damage the ENT organs and upper respiratory system, for example, with otitis media, sinusitis or recurrent tonsillitis.
  • For whooping cough or scarlet fever.
  • For exacerbation of chronic bronchitis, acute bronchitis, lobar pneumonia and other bacterial lesions of the lower respiratory tract.
  • For genitourinary infections, for example, urethritis or pyelonephritis.
  • For gonorrhea.
  • When infected with streptococci or Staphylococcus aureus of soft tissues or skin.
  • For bacterial infections of joints or bones.

At what age is it allowed to take it?

Augmentin is prescribed by pediatricians to children of any age, even infants. At the same time, suspensions with a dosage of amoxicillin of 200 mg or 400 mg per five milliliters do not give babies the first three months of life. Such medications are prescribed in children only from 3 months.

Contraindications

The drug should not be given to a child with hypersensitivity to any component of the suspension, or if allergic to other penicillin antibiotics or cephalosporins. Treatment is also prohibited for phenylketonuria, which is due to the presence of aspartame in the composition.

The medicine is prescribed very carefully to children who have impaired kidney function or liver disease. If infectious mononucleosis is suspected in a baby, the use of Augmentin may cause a measles-like rash.

Side effects

As a result of treatment with Augmentin, a child may develop:

  • Allergies in the form of itching, hives or rash.
  • Loose stools, as well as vomiting or nausea.
  • Worsening of the general blood test - a decrease in the level of platelets and leukocytes, sometimes agranulocytosis and anemia, as well as changes in the parameters of the coagulation system.
  • Candidiasis infection affecting mucous membranes or skin.
  • Increased activity of liver enzymes.
  • Headache or dizziness.

Very rare side effects of taking the suspension include Quincke's edema, anaphylaxis, nervous excitement, convulsions, inflammation of the intestines, stomatitis, discoloration of tooth enamel, nephritis and other negative phenomena. If they occur, stop treatment and immediately consult a doctor.

Instructions for use

To prepare the suspension, boiled and cooled to room temperature water in a certain amount is added to Augmentin powder. In a drug containing amoxicillin at a dose of 125 mg per 5 milliliters, you must first add 60 ml of water. Next, the medicine is shaken and left for 5 minutes, after which more water is added so that its total volume is approximately 92 ml.

If a suspension containing 200 or 400 mg of amoxicillin in five milliliters is used in treatment, then the powder is first mixed with 40 ml of water, and after five minutes a little more water is added to the bottle so that the total amount is approximately 64 ml.

In addition, treatment with the liquid form of Augmentin includes the following nuances:

  • Before each use, the medicine should be shaken so that the separated syrup becomes homogeneous.
  • The measuring cap that comes with the antibiotic bottle helps measure the exact dose of the medication. When the child has drunk the suspension, this cap is thoroughly washed with water.
  • For a child under two years of age, a single dosage of the drug can be further diluted with water 1:1.
  • The regimen of use and the calculation of a single dosage of the medicine are influenced by the child’s age and weight, as well as the condition of the kidneys and the severity of the infection.
  • To ensure that the active substances of the medication are optimally absorbed and the risk of side effects is reduced, it is recommended to take the medicine at the beginning of a meal. The suspension is given to infants during feeding.
  • How many days to take the drug is determined individually in each case, but the minimum course of treatment is considered to be 5 days. In addition, it is not advisable to give the suspension for longer than 14 days.
  • To prevent staining of your teeth, it is recommended that you brush them thoroughly several times a day.

Dosage

Babies in the first three months of life are given only a suspension, the active substances of which are presented in a 4:1 ratio (125 mg/31.25 mg).

To calculate the daily dose of medication, you need to know the baby's weight in kilograms. It is multiplied by 30 and the number of milligrams of amoxicillin is obtained. Dividing the resulting figure by 2, determine the single amount of ml of suspension, which is given to the child twice a day.

For a child aged 3 months to 12 years who weighs less than 40 kilograms, the suspension is dosed as follows:

  • The drug containing active compounds 125 mg/31.25 mg is given three times a day with an interval of 8 hours between doses.
  • A medicine containing active ingredients in an amount of 200 mg/28.5 mg or 400 mg/57 mg is prescribed twice a day, that is, such suspensions are taken twice a day.

If a child has an infection of soft tissues or skin, then Augmentin is prescribed in a low dose. It is represented by 20 mg per 1 kg of the baby’s weight per day for a suspension of 125 mg/31.25 mg/5 ml or 25 mg per day per kilogram of the child’s weight for suspensions with a proportion of active ingredients of 7:1. The same dosage is used for relapses of tonsillitis.

If Augmentin is used to treat otitis media, sinusitis, infections of the joints, genitourinary organs, lower respiratory tract or bones, high doses are used. This is 40 mg per 1 kilogram of the child’s body weight per day for a 4:1 suspension. If the baby is given the drug 7:1, then the dosage will be 45 mg per day per 1 kg of the patient’s weight. All calculations are performed using amoxicillin.

Children over 12 years of age and children weighing more than 40 kg are given 11 ml of a suspension containing 400 mg of amoxicillin and 57 mg of clavulanic acid. The drug is prescribed twice. It should be noted that for such patients it is more preferable to use the medicine in tablet form.

Overdose

If you exceed the dose of suspension prescribed by the doctor, this may disrupt the functioning of the child’s digestive system and affect the water and electrolyte balance in his body. It is also possible for crystals to form in the urine, which can cause an overdose to cause kidney failure. If the child has diseased kidneys, then exceeding the dose can cause seizures.

Interaction with other drugs

  • Combined use with antacids, laxatives or glucosamine impairs the absorption of amoxicillin.
  • When prescribed simultaneously with macrolides (for example, with Sumamed or Azitrox suspension), the effect of Augmentin will be weaker. The same effect is observed when combined with tetracyclines, sulfonamides, lincosamides and chloramphenicol.
  • The suspension can be used together with nitrofurans, for example, the drug Enterofuril.
  • Augmentin should not be given to a child together with allopurinol, as this combination can cause skin allergies.
  • When prescribed with anticoagulants (indirect), the effectiveness of these drugs will increase.
  • The drug is not prescribed together with methotrexate, since penicillins increase its toxicity.

Terms of sale

To buy powder at a pharmacy, you first need to get a prescription from a doctor. The price of one bottle depends on the dosage and can vary from 130 to 250 rubles.

Storage Features

An unopened bottle of powder can be stored until the end of its shelf life, which is 2 years, in a dry place away from children, where the temperature does not rise above +25 degrees. The drug diluted with water should be placed in the refrigerator, but the solution should not be allowed to freeze. The shelf life of liquid medicine is 7 days.

Reviews

Most of the parent reviews about Augmentin suspension are positive. Mothers note that this antibiotic helps cope with many infections and is well tolerated by most children. They confirm that the treatment begins to work quickly when there is a high fever, cough and other symptoms of infection. Within a few days from the start of treatment, the child’s condition improves.

Negative reviews complain about side effects of the drug, such as nausea or diarrhea. Pediatricians, including Komarovsky, speak mostly well of this antibacterial agent, but they emphasize that only a doctor should prescribe such a suspension to a child.

Analogs

You can replace liquid Augmentin with other drugs containing the combination of amoxicillin + clavulanic acid. Amoxiclav, Medoclav, Panclave 2X, Ecoclave, Augmentin EC are produced in the form of a suspension, and Amoxiclav Quiktab and Flemoklav Solutab are produced in the form of soluble tablets.

The doctor may also prescribe drugs based on amoxicillin to the child (Amosin suspension, Flemoxin Solutab tablets or Hiconcil suspension) or drugs in the form of a suspension from the cephalosporin group (Suprax, Pancef, Zinnat and others).

At the same time, only a pediatrician can decide what is best suited as a substitute for Augmentin. A good specialist will take into account the clinical picture and antibiotic sensitivity tests, and then prescribe the correct treatment.

In the following video, the popular children's doctor Komarovsky talks in detail about antibiotics, why they are needed and in what cases they are used.

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Source: http://www.o-krohe.ru/antibiotiki/suspenziya-augmentin/

Augmentin how to drink

How to take Augmentin?

Many antibiotics are used to treat viral and infectious diseases. One of this set is Augmentin. How to take Augmentin and for what diseases?

Augmentin

Augmentin is a broad-spectrum antibiotic containing amoxicillin, clavunic acid and belongs to the penicillin group. Before starting to use this medication, it is necessary to obtain a detailed history of hypersensitivity to penicillins or other allergens. Augmentin is produced in tablets, suspensions, and solutions for injection.

Indications for use

Augmentin is used in the treatment of the following diseases:

  • infections of the upper respiratory tract, ear, nose and throat (sinusitis, otitis media, tonsillitis),
  • lower respiratory tract infections (bronchitis, pneumonia),
  • infections in the kidneys, urinary tract (cystitis, pyelonephritis, urethritis),
  • genital infections, incl. after childbirth, abortion,
  • infections of bones, joints, soft tissues, skin,
  • abdominal infections (peritonitis),
  • dental abscesses

Augmentin is not recommended for use during pregnancy, but there may be exceptions, but only under medical supervision. While breastfeeding, Augmentin may be used.

Taking Augmentin tablets

In most cases, Augmentin tablets are taken. You can find out how to take tablets and in what quantity from the instructions for the drug, but it is better to do this on the recommendation of a doctor. Augmentin is used to prevent infections in patients who have undergone surgery. Augmentin is usually taken every 8 hours three times a day. Augmentin is best absorbed into the blood when taking the tablets before meals. With this intake, the likelihood of developing side effects of bowel function can be minimized. Tablets of this antibiotic must be taken with water.

How much Augmentin to take depends on body weight, age, severity of the disease, infection, and the ability of the kidneys to function. Children under 12 years of age should not be given tablets; they need other dosage forms of Augmentin. The question of how many days Augmentin should be taken is very important. Long-term use may lead to the growth of non-susceptible microorganisms.

The minimum course of therapy is 5 days. After 2 days from the start of treatment, the clinical situation is assessed and a decision is made to continue therapy. The duration of treatment is usually 5-7 days. Treatment of a patient with Augmentin should not last more than 14 days. If necessary, step-by-step therapy is carried out: at first it can be inhalations or injections, and then tablets are taken.

Taking Augmentin in suspension

In addition to tablets and injections, Augmentin suspension is also taken. How to take the suspension, how to prepare it? Augmentin suspension is prepared before the first use. The powder must be dissolved with boiled water cooled to room temperature. Then, shaking, add water to the mark in the bottle, leave the suspension for 5 minutes so that it is completely diluted. The bottle must be shaken before each use. The diluted suspension can be stored in the refrigerator for no more than 7 days, but do not freeze. For accurate dosage of the suspension, use a measuring cap-lid.

Taking Augmentin intravenously

Augmentin by injection must be administered slowly over 3-4 minutes. Through a catheter or directly into a vein with a dropper, inject for minutes. Augmentin is not administered intramuscularly into the patient’s body due to instability in concentration. For serious infections, or in cases where taking oral tablets is impossible for some reason, then injections are given.

How to take Augmentin for children

Augmentin is given to children only in the form of a suspension. For children under one year of age, the suspension should be given 2-3 times a day from 2.5 ml to 5 ml. For children weighing 10 ml, give the suspension 3 times a day, 10 ml. For children weighing 15 ml, give the suspension 3 times a day. For children weighing 20 ml, give the suspension 3 times a day, 20 ml.

Side effects

The use of Augmentin is contraindicated in case of liver diseases or hypersensitivity to antibiotics. When using Augmentin in any form of this medicine: tablets, suspensions, injections, the following side problems may occur:

  • anaphylaxis,
  • allergies, urticaria, skin rash,
  • headache, dizziness,
  • edema,
  • convulsions,
  • nausea, vomiting,

Side effects when taking Augmentin are quite rare and mild. However, the use of any medicine, including Augmentin, must be under the supervision of doctors.

Augmentin

Augmentin is a combined antibacterial agent that has a bactericidal effect against a wide range of microorganisms.

Augmentin powder for suspension preparation Augmentin tablets Augmentin powder

Composition of Augmentin

This medicine contains two active ingredients: the antibiotic from the penicillin group, amoxicillin, and clavulanic acid, the closest “relative” of penicillins.

Amoxicillin is capable of destroying many types of bacteria, including both gram-positive (streptococci, staphylococci, clostridia, etc., according to the annotation) and gram-negative (Escherichia coli, Helicobacter, gardnerella, etc.). However, a number of bacteria have developed a universal defense against the action of this powerful antibiotic in the form of the destructive enzyme beta-lactamase. To inactivate these microbial beta-lactamases, clavulanic acid is needed, which does not itself have bactericidal properties.

That is, the composition of Augmentin was selected taking into account all the pitfalls encountered along the path of antibacterial therapy.

Augmentin analogues, which are its pharmacological substitutes:

  • Rapiklav;
  • Amoxiclav;
  • Arlet;
  • Ecoclave;
  • Flemoklav Solutab.

Release form

The manufacturer of Augmentin is the British pharmaceutical giant SmithKline Beecham Limited. Release forms are presented:

  • 500 mg tablets, 875 mg amoxicillin. The content of clavulonic acid is unchanged – 125 mg;
  • powder for the preparation of a solution for oral administration, 200 mg, 400 mg of amoxicillin for the preparation of 5 ml of suspension. Clavulonic acid is 28.5 mg and 57 mg, respectively.

Indications for use

Indications for the use of Augmentin depend on the sensitivity of pathogenic bacteria to it. It is used in the treatment of:

  • Upper respiratory tract infections (including ear/nose/throat);
  • Lower respiratory tract infections (pneumonia, chronic bronchitis in the acute stage);
  • Skin infections;
  • Infections of the osteo-articular apparatus (osteomyelitis) and soft tissues.

Augmentin for sore throat

Augmentin is the drug of choice for the treatment of bacterial inflammation of the tonsils, i.e. tonsillitis. This medicine is today one of the most commonly used for sore throats caused by pathogenic streptococci or Haemophilus influenzae. Adults should take Augmentin at the rate of 875 mg once a day or 500 mg 3 times a day. The course of treatment for sore throat is usually limited to one week.

Mode of application

Adults and children over 12 years of age with a moderate severity of the infectious process are prescribed one 375 mg tablet three times a day; for severe cases, they are given a 675 mg tablet 3 times a day. If intravenous administration is necessary, the maximum single dose is 1.2 g, injections are made every 6-8 hours. The maximum daily dose is 7.2 g when administered intravenously.

For children under 12 years of age, Augmentin is prescribed in the form of syrup. The powder is diluted with boiled water. A single dose depends on age and is 250 mg for children 7-12 years old, 2 to 7 years old, 62.5 mg for children 9 months to 2 years old. The prescribed doses are also given 3 times a day. When administered intravenously to children, doses are calculated individually depending on body weight. In the presence of renal failure, the dose of Augmentin is reduced and administered with long intervals.

The maximum course of treatment should not exceed two weeks.

The medicine should be taken immediately before meals. The intake and method of using Augmentin must be agreed with your doctor. For children, individual doses are provided depending on their age. There are no differences for men and women.

Contraindications and side effects

  • hypersensitivity to components,
  • liver disorders.

Augmentin during pregnancy and lactation

During pregnancy and during breastfeeding (lactation), it is not recommended to take the drug; this should be an “iron” prescription from a doctor who will take into account all the risks.

Side effects of Augmentin are rare. Thrush, allergies, diarrhea, nausea, vomiting are possible. An overdose of the drug naturally causes more side effects.

special instructions

During treatment with Augmentin, you should not drink alcohol. Drinking alcohol and antibacterial drugs at the same time means ensuring the failure of treatment.

The procedure for dispensing Augmentin from pharmacies is by prescription. It is not used for independent prevention, because Bacteria may develop resistance to the drug, i.e. addiction.

Shelf life - 2 years (for a dosage of 875 mg of amoxicillin), 3 years (for 500 mg).

Additional Information

Dosage of Augmentin for sore throat in adults and children

One of the popular remedies widely used in medicine for sore throat is Augmentin. The combination of amoxicillin (a penicillin antibiotic) and clavulanic acid allows one to achieve a lasting therapeutic effect. The active substances in the drug act by complementing each other. Amoxicillin destroys bacterial cells, and the acid blocks the ability of bacteria to produce beta-lactamases (enzymes that destroy the structure of the antibiotic).

A combined antibiotic based on semi-synthetic penicillins is produced by Russian companies in several forms:

  1. The tablets contain amoxicillin trihydrate and clavulanic acid potassium salt. For ease of use, the active substance is contained in quantities of 375, 675 and 750 mg. Whereas the acid in all tablets is the same, 125 mg.
  2. Powder for oral suspension contains 200 mg amoxicillin and 28.5 mg clavulonic acid.
  3. Powder for the preparation of injection solution is available in a ratio of 500/100 and 1000/200 mg. It is diluted with water for injection, saline and other liquids for the preparation of medicinal solutions.

However, protein liquids based on blood parts and lipid emulsions cannot be used for preparation. When treating with antibiotics of the aminoglycoside group, mixing with Augmentin in the same syringe is not allowed. Aminoglycosides lose their properties.

All forms of release of the product have the same indications and negative effects

Augmentin penetrates into inflamed tissues and accumulates in them. Improvement in the patient's condition is noticeable already on the third day with the correct prescription of the drug.

Treatment of sore throat in adults

Sore throat is an insidious disease. The inflammatory process caused by pathogenic flora quickly develops into purulent formations. Without proper treatment, the respiratory tract becomes infected and progresses to bronchitis or pneumonia. Complications can affect both the cardiac system and the kidneys.

Treatment requires the mandatory use of antibacterial drugs. Augmentin for angina in adults shows good results.

The dosage and method of administration are prescribed by the doctor. The patient's age and body weight are taken into account. The stage of development of the infection is also important.

The instructions for the drug indicate the average consumption rates.

The course of treatment lasts at least 7 days and most often no longer than two weeks. The earlier you start using Augmentin, the easier the disease is tolerable and the lower the likelihood of complications.

At the initial stage of the disease and of average complexity, the drug is prescribed 3 tablets of 0.25 or 2 times a day of 0.5 mg. Manufacturers claim that the absorption of the drug is in no way related to food intake. However, it is believed that it is better to take the tablets immediately before meals.

To enhance the effect, vitamin preparations that strengthen the immune system are prescribed.

For severe forms of tonsillitis in adults, Augmentin injections are recommended. In this case, administration of the medicine is possible only intravenously. Daily injections 2 times a day should be carried out under the supervision of a specialist. Therefore, doctors recommend inpatient treatment.

This video is suitable for those who do not want to go to the hospital for injections. Watch how to give yourself an injection:

Augmentin for children

Like most drugs of the penicillin group, Augmentin has low toxicity. Therefore, this particular drug is recommended for the treatment of sore throat in children.

The drug can be used from the age of two. The dosage is calculated depending on the baby’s weight and exact age.

Augmentin for angina in children is recommended in the form of a suspension, which can be prepared even at home

The powder, packaged in 5 ml, must be filled with 90 g of boiled, cooled water. In this case, to dissolve, it is better to pour in water in parts, shaking.

The prepared suspension is given to the child 2 times a day, maintaining an interval of 12 hours.

  1. For children over 12 years of age, if the weight reaches 40 kg, the adult norm is recommended.
  2. Children from 2 to 6 years old should drink a suspension prepared from 5 ml of Augmentin.
  3. Over 6 years of age and up to 12 years, a portion prepared from 10 ml of the drug is required.

Under no circumstances should you self-treat a child. With frequent treatment with antibiotics of the penicillin group, the body's immunity to their effects may develop.

Dr. Komarovsky will tell you in this video how to correctly calculate the dosage of medicine for a child.

Contraindications and side effects

The manifestation of an allergic reaction to penicillin drugs, which appeared earlier, is a contraindication to the use of Augmentin.

It is not recommended to treat sore throat with this remedy in the first trimester of pregnancy.

There is partial permeability of active substances into mother's breast milk when feeding the baby. In this case, a disorder of the baby’s gastrointestinal tract occurs with subsequent complications in the form of enterocolitis. For an infant, such consequences are severe. The use of Augmentin during lactation should be considered by a doctor on an individual basis, depending on the complexity of the disease and the impossibility of replacing the drug with other anti-infective agents.

Augmentin should not be taken:

  • chronic kidney pathologies;
  • functional disorders of the liver;
  • hepatitis;
  • past infectious diseases;
  • immune system disorder.

Side effects are caused by the action of both components. They can be expressed by a reaction from any organ.

  1. Gastrointestinal tract - nausea and vomiting. Diarrhea often leads to the development of colitis.
  2. Liver - hepatitis may develop due to increased enzyme production.
  3. Immune system - anaphylactic shock caused by an antibiotic can be fatal without medical help.
  4. Skin - rash, itching, redness, peeling.
  5. It is possible to develop candidiasis and some other fungal infections.
  6. Swelling may occur at the injection site and post-injection bumps may form, which most often do not require special treatment. In rare cases, doctors use physiotherapy methods to resolve these hardenings.

Long-term use of Augmentin is often accompanied by headaches and cramps.

Women may experience thrush. This is due to the development of bacteria insensitive to penicillin.

A ban on the use of Augmentin may also be its interaction with medications taken for the treatment of chronic diseases.

It is not recommended to take Augmentin together with diuretics. The permeability of the tubules decreases and Augmentin accumulates in the blood. At the same time, the excretion of clavulanic acid remains at the same level. There is an imbalance in the action of the drug. The effectiveness of the antibiotic decreases and the risk of developing negative side effects increases.

Alternatively, you can try replacing Augmentin with Amoxiclav.

The use of anticoagulants in the treatment of blood diseases and anti-sclerotic therapy leads to an increase in their activity. If it is impossible to refuse treatment with drugs from any of the groups, then you should definitely monitor blood clotting.

Summarize

No matter how much you would like to do without strong pharmaceutical drugs to treat sore throat, you should not do this. Fans of traditional medicine need to think about when the use of natural remedies will be beneficial, and when it threatens enormous damage to health. Self-treatment of sore throat in children can be especially dangerous. Before deciding whether the use of antibiotics is justified, it is recommended to seek advice from a medical institution.

Taking Augmentin for a sore throat

One of the most effective antibacterial drugs used against diseases such as follicular tonsillitis and chronic tonsillitis is the antibiotic Augmentin. Augmentin for sore throat and other diseases is a proven remedy; many doctors recommend it to patients for viral diseases. The popularity of the drug is associated with the wide spectrum of action of the drug. It helps fight bacterial infections that occur due to the penetration of bacteria into the body that are sensitive to the action of the antibiotic. The medicine is used to treat the upper respiratory tract, against infections of the genitourinary tract, pelvic organs, and infections that occur after surgery.

Composition of the drug and spectrum of action

The antibiotic composition contains two powerful substances that create a universal therapeutic mixture. These substances are amoxicillin and clavulanic acid. Amoxicillin destroys harmful microorganisms, clavulanic acid provides resistance to bacteria. Together they have a positive healing effect on the patient’s body.

Augmentin is equally effective against gram-positive and gram-negative microorganisms that cause sore throat.

Distribution in the body

The patient's intake of food does not affect the body's digestion of the medicine. The patient takes Augmentin, the drug enters the digestive tract, then accumulates in the inflamed areas. A small amount of the components of the drug passes into breast milk, the rest is destroyed in the liver and excreted through the urine.

Variety of release forms and dosages

The antibiotic is available in various forms - tablets, powder for preparing a mixture or injection, syrup. For angina, injections are used extremely rarely. For young children, the drug is produced with a fruit flavor in the form of a suspension. For adults and children over twelve years of age, tablets are used according to the following dosage:

  • 1 tablet 2-3 times a day at a dosage of 875 mg/125 mg;
  • 1 tablet 3 times a day at a dosage of 500 mg/125 mg.

Separated by a slash is the ratio of amoxicillin to clavulanic acid. Adults are recommended to take Augmentin for sore throat for at least seven days; if the form of the disease is more complex, for two weeks.

Side effects

Any use of antibiotics has an undesirable effect on the human body. With Augmentin, allergic side effects sometimes occur - rash in mild cases, angioedema in more serious cases. Symptoms after taking this drug can be unpleasant: constipation or diarrhea, bloating, physical weakness, exhaustion, insomnia, excessive agitation. You should definitely consult a doctor if you feel discomfort after taking the medicine. Perhaps the doctor will tell you which alternative drug can replace Augmentin in your case.

It is recommended to take a drug that normalizes the microflora along with an antibiotic.

To prevent the occurrence of dysbiosis after taking this medication, it is recommended to take a course of drugs that contain beneficial bacteria, for example, Linex or Lactobacterin, along with the antibiotic.

It is necessary to carefully study the instructions if the patient is taking any other medications in parallel with Augmentin, in order to avoid drug incompatibility. Also, if you drink alcohol, the effect of the antibiotic will significantly decrease or disappear altogether.

Contraindications

There are main contraindications for which taking Augmentin is unacceptable:

  • Allergic reactions of the body to amoxicillin or clavullanic acid, penicillins. A patient who has previously suffered an allergy to penicillins runs the risk of having an extremely difficult reaction to the action of Augmentin. Even fatal reactions to the drug have occurred in such patients.
  • For chronic kidney diseases, Augmentin can be taken if the drug has been prescribed by a doctor, in limited quantities.
  • Impaired liver function, jaundice.
  • Being in the recovery period after viral infections is a contraindication for taking Augmentin, because the body is not yet strong enough after the infection.
  • Pregnancy, especially the first trimester.

In most cases, this antibiotic is well tolerated by patients without visible consequences.

For children

If a child has a sore throat, it is necessary to give him Augmentin in the form of a suspension. The dose of the medicine depends on the child’s individual parameters - body weight, age. If the child weighs more than forty kilograms, the dose may be the same as an adult. Young children with sore throats should be given prescribed doses of medication: from two to six years old - 5 ml, from seven to twelve - 10 ml twice a day. It is better to treat a child under two years old with another medicine, because there is no scientific data yet on the tolerability of Augmentin in such children.

Before treating your child, you should consult your pediatrician. He must prescribe Augmentin, because you can buy this drug at the pharmacy only with a prescription. The pediatrician may also change the dosage of the medication.

During breastfeeding and pregnancy

During pregnancy, it is advisable to avoid taking Augmentin. However, a doctor may prescribe a pregnant woman treatment with this drug in some cases, if extreme measures are necessary - only during the second and third trimester. Taking the medicine threatens the development of necrositating entercolitis in a newborn baby; this disease is quite dangerous. A breastfeeding woman should also not take Augmentin, or the young mother should temporarily stop breastfeeding while taking the antibiotic. Amoxicillin, together with clavulanic acid, penetrates into milk. Consequences for the baby may include intestinal disorders. Sometimes the baby's oral mucosa becomes infected with fungi.

Therefore, pregnant women and young mothers should engage in careful health prevention in order to avoid the need for antibiotic treatment in the first place.

Compatibility with other drugs

Augmentin cannot be taken with all medications. For example, Probenecid will significantly reduce the effectiveness of amoxicillin, increase its concentration and retain it in the blood. It is not recommended to take Augmentin in parallel with Allopurinol. This can have undesirable consequences in the form of allergic reactions on the skin: rash, itching. You should be careful about the amount of Augmentin taken at a time. An overdose of the drug causes vomiting, nausea, and malaise.

How effective?

Most of Augmentin's contraindications apply to all antibiotics, so it is not dangerous to health. In fact, there are no drugs without side effects; each therapeutic drug is individual for each organism.

This drug is primarily used to treat upper respiratory tract infections.

Augmentin has a wide spectrum of action. It is recommended by many doctors and helps against a large number of diseases - runny nose, chronic tonsillitis, bronchitis, sore throat, viral infections, colds. The medicine is one of the ten best-selling and most popular antibiotics. Patients and doctors confirm that the effectiveness of this drug is high, it is able to destroy pathogenic microorganisms. Augmentin helps fight infections of the upper and lower respiratory tract, infections of the skin, oropharynx, ENT infections, diseases of the genitourinary system, osteoarticular system, and soft tissues.

However, it will be much more effective to combine Augmentin with a course of other drugs. For normal functioning of the gastrointestinal tract and the absence of side effects, it is recommended to take the antibiotic after meals. It should also be said that Augmentin significantly reduces the effectiveness of contraceptives.

Recommendations for admission

Before you start taking Augmentin, you must collect information about allergic hypersensitivity reactions to penicillins, cephalosporins or similar substances. Ignoring these allergies can lead to dangerous side effects, so it is strictly forbidden to take Augmentin if they occur. If a patient with hypersensitivity to penicillins began treatment with Augmentin, you should stop taking the medication and start another therapy.

It is also necessary to regularly visit the doctor so that he can assess the condition of the kidneys and liver. For kidney diseases, Augmentin is prescribed according to the degree of illness.

The drug can also sometimes cause dizziness, so patients driving a vehicle should be extremely careful when taking this antibiotic.

Augmentin is a proven, effective remedy for diseases, but in order to take it usefully, avoiding undesirable consequences, you need to be interested in the contents of the instructions, be sure to consult with your doctor about the medicine, and know information about all sorts of side effects. Sore throat, tonsillitis, bronchitis are serious diseases, so when dealing with them you should take responsibility for your own health and avoid complications.

Self-medication, especially with antibiotics, can give the exact opposite of the desired effect, or have absolutely no effect in the fight against diseases. Therefore, the patient must visit a doctor for consultations. It must be remembered that even a minor cold can result in a serious illness, and it is dangerous to overuse antibiotics.

Source: http://vseantibiotiki.ru/antibiotiki-shirokogo-spektra/augmentin-kak-pit.html