Acyclovir ointment use

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Antiviral ointment Acyclovir: instructions for use

Acyclovir is a drug that has an antiviral effect, mainly aimed at the herpes simplex virus and herpes zoster.

This ointment inhibits the DNA synthesis of the pathogen of the listed diseases.

Table of contents:

Suppresses the process of the appearance of new elements of herpetic eruptions, reduces the risk of complications, reduces pain in the acute period of the disease, and promotes faster formation of crusts.

On this page you will find all the information about Acyclovir: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Acyclovir ointment. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antiviral drug for local use.

Conditions for dispensing from pharmacies

Available without a prescription.

How much does Acyclovir cost in ointment form? The average price in pharmacies is 20 rubles.

Release form and composition

Two types of ointment are available, which are divided depending on the concentration of the active substance - acyclovir itself.

  • 5% - used for external use on more resistant skin and mucous membranes.
  • 3% - for treating the mucous membranes of the eyes.

The most common form of release is an ointment, but the drug comes in the form of cream, tablets and injection solution, but in this form it is used much less frequently.

Pharmacological effect

The main active ingredient of the ointment is acyclovir, which belongs to the group of synthetic analogues of deoxyguanidine . This substance is a component of DNA. Acyclovir is active against herpes simplex viruses type 1 and 2, which cause not only herpes, but also herpes zoster and chickenpox. The ointment exhibits moderate activity when exposed to Epstein-Barr viruses and cytomegaloviruses.

After application to the skin, acyclovir ointment penetrates directly into cells infected with a microorganism, that is, a virus. In cells, acyclovir interacts with viral enzymes, disrupts their normal development and thus breaks the chain of reproduction of pathogenic microorganisms. The drug has no effect on healthy cells.

Indications for use

The instructions for Acyclovir state that the ointment is effective against the following ailments:

  • chicken pox;
  • herpes zoster;
  • herpetic keratitis;
  • any infectious lesions of the skin caused by herpes Herpes Simplex types 1 and 2;
  • chronic and primary herpes on the mucous membranes of the lips and genitals;
  • damage by cytomegalovirus;
  • in case of damage to the skin of patients after surgery;
  • for the prevention of herpes damage to the skin and mucous membranes of patients with severe damage to the immune system due to chemotherapy or radiation therapy.

Contraindications

Acyclovir in the form of an ointment is not prescribed if the body's sensitivity to the main component of the drug or to the auxiliary ingredients is increased.

Use during pregnancy and lactation

The use of the drug during pregnancy is possible if the potential benefit to the mother outweighs the possible risk to the fetus.

The drug is found in breast milk after entering the mother's systemic circulation, so breastfeeding should be discontinued during treatment

Instructions for use

The instructions for use indicate that Acyclovir in the form of an ointment is used to treat herpes and lichen on the lip, in the intimate area, on the mucous membranes and on other skin areas.

Recommendations for use:

  1. Therapy should begin after noticing the initial symptoms - burning, itching, redness. If herpetic blisters have already appeared, it is important to avoid rupturing them so as not to spread the infection further during treatment.
  2. To prevent the spread of the virus, it is also necessary to use a cotton swab or gloves (all disposable) to apply the cream.
  3. The affected area and a small area around it (up to 5 mm) are covered with a thin layer of cream every 4 hours, with the exception of 8 hours of sleep at night.
  4. On average, the infectious process stops in 5 days, but with extensive inflammation, the course will need to be increased to 10 days.

Acyclovir eye ointment in the form of a strip 1 cm long is placed in the lower conjunctival sac 5 times a day (every 4 hours) until healing. Treatment is continued for another 3 days after healing.

Side effects

External use of ointment can cause the following side effects:

  1. Allergic reactions - urticaria, allergic dermatitis, blurred vision when putting the ointment into the conjunctival sac, swelling of the eyelids, keratopathy, blepharitis, conjunctivitis.
  2. On the part of the skin – itching, burning, soreness, redness, increased rash.

special instructions

Being one of the very first antiviral drugs, Acyclovir ointment brings the greatest effect in case of primary infection with the herpes virus when treatment is started in the early stages of the disease. About 60% of patients with a recurrent form of the disease suffer from reduced immunity, against which an infection has developed, so for the best effect, dermatologists prescribe immunostimulants and immunomodulators along with Acyclovir cream.

When applying the ointment into the conjunctival sac, a temporary deterioration in vision is possible, which can affect the ability to adequately drive vehicles and complex mechanical devices, therefore, after Acyclovir ointment gets into the eye, it is better to wait a while for the product to dissolve before driving a car. In addition, you need to look at the release date so as not to use an expired medicine.

Drug interactions

The simultaneous use of Acyclovir ointment with other oral antiviral drugs enhances the therapeutic effect of the ointment.

Simultaneous external use of ointment with Acyclovir tablets increases the risk of side effects if the dosage of the drug is incorrectly calculated.

Reviews

We have selected some people's reviews about the drug Acyclovir in ointment form:

  1. Masha. Herpes often bothers me, especially after or during colds. It appears mainly on the lips and on the nasal septum. I was looking for an effective ointment; the pharmacy offered me an inexpensive drug, acyclovir, which I used regularly, according to the instructions, treating the affected areas several times a day. But, unfortunately, I did not get the expected effect - with or without the ointment, the duration of the infection was the same.
  2. Svetlana . I have a recurrence of genital herpes almost every spring and autumn. During this period, I take medications prescribed by the doctor and at the same time apply Acyclovir cream, it is well absorbed and significantly reduces discomfort.
  3. Lana. Hi all! Previously, Herpes tormented me very often, as soon as I caught a cold, how about you... This thing pops up on my lip. But after, on the doctor’s recommendation, I started using Herpferon (which contains Acyclovir), now I get herpes no more than 1-2 times a year. Usually it’s autumn and spring, as soon as your lips get chapped - bam. Wait the next day - here it is. Or from nerves. It only comes out on the lower lip. It’s a good ointment and it helps quickly, 2-3 days and it’s all gone. I am very pleased, I advise anyone who has the same problems to try it! Now herpes is not a problem for me.
  4. Marina. Unfortunately, I have the herpes virus and periodically makes itself felt. I used to use Acyclovir cream, but it didn’t help much. Then I switched to an ointment in which the concentration of the drug was twice as high. The ointment effectively removes rashes and therefore is always in my purse. The good news is that the drug is harmless and can be used with virtually no restrictions. In addition, it increases local immunity, as a result of which I am protected for some time from repeated manifestations..

Analogs

The most famous and frequently prescribed analogues of Acyclovir ointment based on the active ingredient:

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25 °C. Shelf life: 3 years.

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One comment

Once in the hospital I was infected with the herpes virus during a nose operation, as a result of which my entire face was covered with watery sores, right down to my ears. A lot of time has passed, and herpes periodically appears on the lip. I save myself with Acyclovir or burn it with toothpaste. To be honest, this is the first time I’ve heard that barley can be treated. My sister suffers from this disease; once she even had to cut her eye. But I still wouldn’t risk applying this product to the mucous membrane; I think there is something softer.

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Source: http://simptomy-lechenie.net/maz-aciklovir/

Acyclovir ointment instructions for use, application

• primary or recurrent (recurrent) genital herpes, both in men and women;

The instructions indicate that the ointment is applied to the affected area of ​​the skin or mucous membrane at regular intervals, up to 5-6 times a day. A 1.25 cm long strip of ointment is applied to 25 cm2 of affected skin. To avoid autointoxication, this procedure is recommended to be carried out with finger caps and/or gloves.

Therapy should be continued until crusts appear at the site of the vesicles or until they disappear completely.

• Burning and soreness at the application site.

• Ointment 3% for the treatment of viral infections on mucous membranes, in tubes.

• Avoid applying ointment intended for cutaneous use to the mucous membranes (nose, eyes, vulva); there is a special form for this.

• Do not shower or wash immediately after applying the ointment.

• In patients with a sharp decrease in immunity (after chemotherapy and/or radiation, HIV/AIDS infection, organ or bone marrow transplantation), systemic administration of the drug is recommended for the treatment of hepatic infection.

After the expiration date, the ointment is not used.

Source: http://www.rasteniya-lecarstvennie.ru/3133-aciklovir-maz-instrukciya-po-primeneniyu-primenenie.html

ACICLOVIR ointment

Drug: ACICLOVIR

Active substance: aciclovir

ATX code: D06BB03

KFG: Antiviral drug for external use

ICD-10 codes (indications): A60, B00, B01, B02

Reg. number: LP

Registration date: 03/01/11

Owner reg. credential: OZONE (Russia)

DOSAGE FORM, COMPOSITION AND PACKAGING

5 g - aluminum tubes (1) - cardboard packs.

10 g - aluminum tubes (1) - cardboard packs.

5 g - glass jars (1) - cardboard packs.

10 g - glass jars (1) - cardboard packs.

15 g - glass jars (1) - cardboard packs.

20 g - glass jars (1) - cardboard packs.

25 g - glass jars (1) - cardboard packs.

30 g - glass jars (1) - cardboard packs.

INSTRUCTIONS FOR USE FOR SPECIALISTS.

The description of the drug was approved by the manufacturer in 2011.

An antiviral drug, a synthetic analogue of thymidine nucleoside, which has a highly selective effect on herpes viruses. Inside virus-infected cells, under the influence of viral thymidine kinase, a series of sequential reactions of transformation of acyclovir into mono-, di- and triphosphate of acyclovir takes place. Acyclovir triphosphate is incorporated into the viral DNA chain and blocks its synthesis through competitive inhibition of viral DNA polymerase.

The specificity and very high selectivity of action are also due to its predominant accumulation in cells affected by the herpes virus. Highly active against Herpes simplex virus types 1 and 2; the virus that causes chickenpox and herpes zoster (Varicella zoster); Epstein-Barr virus (types of viruses are listed in increasing order of the minimum inhibitory concentration of acyclovir). Moderately active against cytomegalovirus.

In case of herpes, it prevents the formation of new rash elements, reduces the likelihood of skin dissemination and visceral complications, accelerates the formation of crusts, and reduces pain in the acute phase of herpes zoster.

When applying the ointment on intact skin: absorption is minimal; not detected in blood and urine.

Affected skin: absorption is moderate; in patients with normal renal function, the concentration in the blood serum is up to 0.28 mcg/ml, in patients with chronic renal failure - up to 0.78 mcg/ml. Excreted by the kidneys (up to 9.4% of the daily dose).

Herpes simplex of the skin and mucous membranes, genital herpes (primary and recurrent); localized herpes zoster (auxiliary treatment).

The ointment is applied to the affected areas of the skin 4-6 times a day (as early as possible after the onset of infection). A 1.25 cm strip of ointment should be applied to 25 cm2 of affected skin. It is important to begin treatment for a recurrent infection during the prodromal phase or at the very beginning of the infection. The duration of treatment is at least 5 days, maximum 10 days.

When used externally - pain, burning, itching, skin rash, vulvitis, allergic reactions, swelling at the site of application.

Use during pregnancy is only possible if the expected benefit to the mother outweighs the potential risk to the fetus. If it is necessary to take acyclovir during lactation, interruption of breastfeeding is required.

The ointment should not be applied to the mucous membranes of the mouth and eyes. Acyclovir ointment is effective in preventing recurrences of herpes labialis. The earlier it is started (at the first signs of infection), the higher the effectiveness of treatment.

To realize the therapeutic effect of acyclovir, the state of the body's immune system is important. Patients with reduced immunity (with HIV/AIDS or after bone marrow transplantation) against the background of topical use of acyclovir ointment should be prescribed systemic administration of the drug, as well as in the case of severe and recurrent herpes infection.

To prevent autoinoculation to other areas of the skin, it is necessary to use finger caps or rubber gloves.

Acyclovir does not prevent the sexual transmission of herpes, so during the treatment period it is necessary to abstain from sexual intercourse, even in the absence of clinical manifestations.

Influence on the ability to drive vehicles and operate machinery. Acyclovir does not affect the ability to drive vehicles and perform work that requires an increased speed of psychomotor reactions.

Currently, no cases of drug overdose have been reported.

An enhanced effect is observed with the simultaneous administration of immunostimulants.

The drug is approved for use as a means of OTC.

In a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children.

Best before date. 3 years. Do not use after expiration date.

Source: http://docvita.ru/Details/ACIKLOVIR-maz.html

Acyclovir

5 g - aluminum tubes (1) - cardboard packs.

10 g - aluminum tubes (1) - cardboard packs.

5 g - glass jars (1) - cardboard packs.

10 g - glass jars (1) - cardboard packs.

15 g - glass jars (1) - cardboard packs.

20 g - glass jars (1) - cardboard packs.

25 g - glass jars (1) - cardboard packs.

30 g - glass jars (1) - cardboard packs.

An antiviral drug, a synthetic analogue of thymidine nucleoside, which has a highly selective effect on herpes viruses. Inside virus-infected cells, under the influence of viral thymidine kinase, a series of sequential reactions of transformation of acyclovir into mono-, di- and triphosphate of acyclovir takes place. Acyclovir triphosphate is incorporated into the viral DNA chain and blocks its synthesis through competitive inhibition of viral DNA polymerase.

The specificity and very high selectivity of action are also due to its predominant accumulation in cells affected by the herpes virus. Highly active against Herpes simplex virus types 1 and 2; the virus that causes chickenpox and herpes zoster (Varicella zoster); Epstein-Barr virus (types of viruses are listed in increasing order of the minimum inhibitory concentration of acyclovir). Moderately active against cytomegalovirus.

In case of herpes, it prevents the formation of new rash elements, reduces the likelihood of skin dissemination and visceral complications, accelerates the formation of crusts, and reduces pain in the acute phase of herpes zoster.

When applying the ointment on intact skin: absorption is minimal; not detected in blood and urine.

Affected skin: absorption is moderate; in patients with normal renal function, the concentration in the blood serum is up to 0.28 mcg/ml, in patients with chronic renal failure - up to 0.78 mcg/ml. Excreted by the kidneys (up to 9.4% of the daily dose).

Herpes simplex of the skin and mucous membranes, genital herpes (primary and recurrent); localized herpes zoster (auxiliary treatment).

The ointment is applied to the affected areas of the skin 4-6 times a day (as early as possible after the onset of infection). A 1.25 cm strip of ointment should be applied to 25 cm2 of affected skin. It is important to begin treatment for a recurrent infection during the prodromal phase or at the very beginning of the infection. The duration of treatment is at least 5 days, maximum 10 days.

When used externally - pain, burning, itching, skin rash, vulvitis, allergic reactions, swelling at the site of application.

Use during pregnancy is only possible if the expected benefit to the mother outweighs the potential risk to the fetus. If it is necessary to take acyclovir during lactation, interruption of breastfeeding is required.

The ointment should not be applied to the mucous membranes of the mouth and eyes. Acyclovir ointment is effective in preventing recurrences of herpes labialis. The earlier it is started (at the first signs of infection), the higher the effectiveness of treatment.

To realize the therapeutic effect of acyclovir, the state of the body's immune system is important. Patients with reduced immunity (with HIV/AIDS or after bone marrow transplantation) against the background of topical use of acyclovir ointment should be prescribed systemic administration of the drug, as well as in the case of severe and recurrent herpes infection.

To prevent autoinoculation to other areas of the skin, it is necessary to use finger caps or rubber gloves.

Acyclovir does not prevent the sexual transmission of herpes, so during the treatment period it is necessary to abstain from sexual intercourse, even in the absence of clinical manifestations.

Influence on the ability to drive vehicles and operate machinery. Acyclovir does not affect the ability to drive vehicles and perform work that requires an increased speed of psychomotor reactions.

Currently, no cases of drug overdose have been reported.

An enhanced effect is observed with the simultaneous administration of immunostimulants.

In a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children.

Best before date. 3 years. Do not use after expiration date.

The scientific information provided is general and cannot be used to make a decision about the possibility of using a particular drug.

There are contraindications, consult your doctor.

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What does Acyclovir help with: herpes, stomatitis, vision?

Why and what does Acyclovir ointment help with? Instructions for use of the drug, indications and contraindications for its use, detailed description of the composition and analogues of the drug.

The material also contains patient reviews and their criticisms. The information will be useful to everyone who has used or is planning to use this tool.

Description

What is this remedy used for? Acyclovir ointment is a very effective antiviral drug that acts selectively on the herpes virus, stopping its development.

As you know, herpes affects the skin and mucous membranes of humans, so the drug is available in the form of an ointment, predominantly pale yellow in color. External use only.

Two types of ointment are available, which are divided depending on the concentration of the active substance - acyclovir itself.

  1. 5% - used for external use on more resistant skin and mucous membranes.
  2. 3% - for treating the mucous membranes of the eyes.

It is worth noting that the ointment does not help with acne that is of bacteriological origin.

The most common form of release of Acyclovir is ointment, but it also comes in the form of cream, tablets and injection solution, but in this form it is used much less frequently.

Compound

As mentioned above, the main active ingredient is acyclovir. In a classic ointment, its amount should be at least 5%. The primary excipients include:

These substances are also present in the eye ointment, but due to the specific application, the amount of acyclovir there does not exceed 3%.

Indications for use

Acyclovir is great for treating herpes, but its field of application is much wider. Due to the specific composition and action, it is also used in the following cases:

  • herpes in the first and second stages - use prevents the spread of the rash, reduces the risk of complications, accelerates the healing of affected areas. It works equally effectively both when a rash appears on the skin and when herpes appears on the mucous membranes, for example, on the lips. The drug is used for herpes stomatitis;
  • herpetic kerotitis - inflammation of the cornea of ​​the eye, in this case 3% acyclovir ointment is used;
  • chickenpox and shingles - in the case of chickenpox in adults, it is recommended to treat acne with acyclovir to make the disease easier;
  • the appearance of herpes due to immunodeficiency caused by HIV, severe surgery or chemotherapy;
  • barley - the effectiveness in this case will be quite limited, since this disease is of a bacteriological nature, and the profile of acyclovir is viral diseases. But the ointment contains an antibiotic, which makes it possible to treat barley.

Contraindications

The drug has a number of contraindications, which are caused by the specifics of its action and the characteristics of its composition. Most often, problems arise in people with individual intolerance to its components.

If Acyclovir ointment is used incorrectly, the following undesirable effects may occur:

  1. Discomfort and pain at the site of application of the ointment.
  2. The appearance of rashes and itching, allergic reactions in the form of urticaria.
  3. In women, inflammation of the external genital organs (vulvitis).

If you experience one or more of the symptoms listed above, you should immediately stop using the drug and seek help from a doctor. As a rule, after stopping the procedures, the symptoms quickly disappear, but this does not happen in all cases. Sometimes additional help and treatment may be needed.

Disputes continue over whether the ointment can be used during pregnancy and lactation. To date, relevant research is being carried out, but the question remains open.

Instructions for use

How to take Acyclovir ointment correctly? To avoid complications and make treatment as effective and quick as possible, you must adhere to the following instructions:

  • apply the ointment using medical gloves or special finger caps to avoid getting the ointment on healthy areas of the body;
  • The minimum interval between repeated applications should be at least 4 hours. Their maximum number should be no more than 5-6 times a day. For elderly people and patients with renal failure, this figure is no more than 2-3 times per 24 hours;
  • treatment continues until the herpes rash dries, which usually occurs 5 to 10 days after the start of the procedures. If the drug has not given positive results during this time, you should consult a doctor;
  • to avoid washing off the ointment, do not shower for 1.5-2 hours after applying it;
  • Only the affected areas should be smeared, and the amount of the drug should cover the entire painful area with a thin but dense layer.

► Acyclovir does not prevent people who come into contact with you from becoming infected. When in their company, remember this!

In the case of chickenpox in childhood, you should not use the drug, since the disease in children is milder than in adults.

Separately, it is worth talking about the use of 3% Acyclovir ointment for diseases of the mucous membrane of the organs of vision.

  1. The drug is used no more than 5 times a day for three days. This course of treatment is the safest for the patient’s eyes.
  2. The ointment is usually applied by placing it behind the conjunctival sac.
  3. It is not recommended to wear contact lenses during eye treatment.
  4. For herpes kerotitis, Acyclovir alone may not be enough, so additional remedies are often used (Zorax drops, for example), but only after consulting a doctor.

Analogs

Drugs that are closest in action to acyclovir include:

It is worth noting that each of them uses the same acyclovir as the main active element. The drugs differ in price, with Acyclovir being one of the cheapest drugs in this group, the most expensive drug being Zovirax.

Video: Acyclovir - choice of form and tolerability of the drug, consequences.

Reviews

I always have Acyclovir ointment in the refrigerator and when signs of a cold appear on my lips, this medicine helps perfectly. As a rule, the blisters disappear within 2-3 days after starting use. In addition, it can be used to smear pimples with chicken pox. A small tube of five grams lasts a very long time. I bought it a long time ago, so I can’t say the exact price, but I know that it’s cheap.

I very often come across a cold on my lip, I used to suffer very much from it and didn’t know how to treat it, but recently the pharmacy recommended Acyclovir to me. It's inexpensive and at first I thought it wouldn't help. This ointment should be taken at the first signs of the disease, and as soon as redness and itching appeared, I immediately applied it, and it helped me. It was not always possible to apply it as written in the instructions, but the drug helped anyway. I recommend him to everyone!

For me, the herpes virus is a real nightmare. It is almost impossible to get rid of it, unless you constantly strengthen your immune system so that the rash does not appear so often. All folk recipes did not help me, and I consider them useless. The only option to more or less quickly eliminate herpes is to anoint it with Acyclovir or a drug based on it. After 2-3 days, the pimples begin to dry out, and the pain disappears immediately. The price is very affordable, so I recommend it to everyone.

Additional questions

► Can I use it during pregnancy?

Use during pregnancy is not advisable, since animal tests have shown that elements of Acyclovir can cross the placenta. However, doctors' opinions differ. Some believe that the drug can be used when a viral infection of the mother poses a greater danger to the child than the use of the medicine itself. In any case, visit your doctor first.

► While breastfeeding?

During lactation, the use of Acyclovir is also not recommended, since its elements tend to penetrate into mother's milk and can harm the baby. But if the doctor believes that the use is necessary, he can still prescribe it.

► Acyclovir – cream or ointment: which is better?

The use of cream or ointment depends on the areas where the rash appears. If it occurs on the lips or face, then it is better to use ointment; it lasts longer and will help avoid injury to problem areas. If herpes appears on the body at the point of contact with clothing, then you can use a cream that is absorbed faster and does not leave stains.

The shelf life of Acyclovir is 3 years. It should be stored out of the reach of children, at a temperature of +15 to +25 Celsius. It is worth noting that after opening the tube, the manufacturer recommends using the ointment for a month.

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Once in the hospital I was infected with the herpes virus during a nose operation, as a result of which my entire face was covered with watery sores, right down to my ears. A lot of time has passed, and herpes periodically appears on the lip. I save myself with Acyclovir or burn it with toothpaste. To be honest, this is the first time I’ve heard that barley can be treated. My sister suffers from this disease; once she even had to cut her eye. But I still wouldn’t risk applying this product to the mucous membrane; I think there is something softer.

And purely out of intuition, I applied Acyclovir to the chicken pox pimples. They went by much faster. It turns out that the ointment can really be used for this disease.

Colds on the lips appear periodically. To get rid of it I always use acyclovir. It turns out that the ointment is so universal and can be used for barley and chickenpox. Thank you for the article.

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What does Acyclovir ointment help with?

Acyclovir ointment is an antiviral drug that is effective against the herpes virus, which causes diseases of the mucous membranes and skin. The substance acyclovir is an analogue of a DNA component called purine nucleoside, which is responsible for hereditary information. The same structure allows acyclovir to successfully interact with herpes simplex viral enzymes, interrupting their reproduction. How to use the ointment, what are its indications and side effects, let's figure it out.

Release form and composition of Acyclovir ointment

Acyclovir 5% ointment for external use is produced in aluminum tubes of 20 grams. Each tube is packed in a cardboard box, which comes with instructions for using the drug. The active component of the ointment, which is white-yellow in color and without any odor, is the substance acyclovir. Auxiliary components in the ointment:

pharmachologic effect

Acyclovir selectively acts on the synthesis of viral DNA. The substance has no effect on DNA replication of human cells. Absorption of the ointment inside occurs by 20%. The drug is excreted from the body after 3 hours through the kidneys. In patients with kidney failure, this process can take up to 20 hours. The high effectiveness of the antiviral agent is determined by its accumulation in cells affected by the herpes virus.

Indications for use

Indications for the use of antiviral drugs are extensive. Aciclovir prevents the formation of a new rash, reduces the likelihood of complications of herpes on internal organs and the spread of the virus through the skin, relieves pain in the acute phase of the disease, accelerates the formation of crusts on weeping areas of herpes. According to the instructions for use, Acyclovir ointment is prescribed for the following pathologies:

  • Varicella (chickenpox).
  • Shingles.
  • Infection of the mucous membranes of the genital tract and genitals by the herpes virus (genital herpes).
  • Herpetic skin rashes.
  • Herpetic stomatitis.

Instructions for use of Acyclovir ointment

The topical drug should be used as prescribed by a doctor, depending on the diagnosis, the severity of the viral infection and the individual characteristics of the body. For herpes zoster, according to the instructions for use, the treatment method is as follows: the product is applied daily to the affected area 2-3 times for about 7 days. After completion of treatment, the ointment should be applied for another 3 days to prevent relapse.

To treat herpes in the nose or colds on the lips, Acyclovir should be applied up to 3 times a day, having first cleaned the application site of cosmetics and dust. The course of therapy in this case should not exceed 5 days. If during this period there is no positive dynamics, then contact your doctor again to correct therapeutic actions.

Contraindications and side effects

Judging by patient reviews, Acyclovir ointment is well tolerated. Adverse reactions may occur during treatment if the drug is used incorrectly. Among them, itching, skin hyperemia, burning, allergic rashes, swelling, dryness, flaking are observed when the dosage is exceeded or the drug is used for a long time. Therapy with Acyclovir is contraindicated if the patient is intolerant to the components of the ointment and after the expiration date of 2 years.

Use during pregnancy

Doctors do not recommend using acyclovir ointment during pregnancy in the 1st trimester and 2nd trimester. Although there is no data on harm to the fetus, during this period the child’s internal organs are growing, and the use of any medications can lead to disruption of the process. The use of Acyclovir ointment during the 3rd trimester should be discussed with a gynecologist.

It is also not recommended to use the drug during lactation, since the active component of the drug passes into breast milk and can accumulate in the newborn’s body, causing severe dysfunction of the liver and kidneys. If it is necessary to use the drug, then the child must be switched to artificial feeding for this period.

special instructions

The herpes virus is very contagious, so it is better to refrain from sexual contact while using the product. Acyclovir ointment is prescribed to children upon reaching 3 years of age in a dosage not exceeding a daily dose of 800 mg, so that there is no risk of adverse reactions.

Numerous reviews of the drug indicate that the active substance does not inhibit the functioning of the central nervous system, therefore during therapy it is allowed to drive a car and other mechanisms that require a quick reaction. It is important to start treatment with the drug when the disease is still in a relapsing stage. When the ointment is used externally, no interaction with other medications has been identified.

How much does Acyclovir ointment cost? The price of the drug in Russian pharmacies ranges from 20 to 30 rubles per tube. The cost of eye ointment is 3% rubles per 1 unit. Acyclovir tablets cost about rubles per pack of 25 pieces. The drug can be purchased at any retail outlet without presenting a prescription from a doctor.

Analogs of Acyclovir ointment

  1. Famvir. An effective analogue of Acyclovir, indicated for the treatment of viral infections caused by herpes simplex with decreased immunity. Prescribed for ophthalmoherpes, postherpetic neuralgia.
  2. Immunofan. Used for immunodeficiency in adults and children of various origins: psoriasis, diphtheria, rheumatoid arthritis. Gives high results in treatment of burns, in complex therapy of hepatitis C and B, and also in HIV therapy.
  3. Valtovir. It is used for the prevention and treatment of skin diseases caused by the herpes simplex virus of the first and second types, including genital, herpes zoster, and herpes simplex.

Reviews

Alina, 46 years old: Acyclovir is an effective remedy for herpes, but if you use it in the early stages of its occurrence, when acne appears. If you miss the initial stage, then no ointment for herpes will help - the lip grows, cracks and becomes wet, causing pain and aesthetic horror: not like in the photo, you don’t want to look in the mirror.

Fedor, 29 years old: Acyclovir ointment helps me get rid of relapses of genital herpes, although in combination with pills. Unfortunately, it is not possible to be completely cured, but in the autumn-spring period, when the initial clinical symptoms appear, I immediately apply the ointment and take a course of antiviral tablets, and then the disease recedes.

Source: http://wjone.ru/318-aciklovir-maz

Acyclovir ointment instructions for use

The drug Acyclovir is a powerful antiviral agent intended for external use, which is highly effective against herpes simplex viruses types 1 and 2.

Release form and composition of the drug

This medicine is available in the form of a 5% ointment for external use in aluminum tubes of 20 g. The tubes are packaged in a cardboard box.

The main active ingredient of the ointment is acyclovir. Excipients – emulsifier No. 1, nipazole, nipagin, purified water, lipocomp “C”. The ointment is a homogeneous substance of white or white with a yellowish tint, without any sharp or specific odor.

Indications for use of the drug

Acyclovir ointment is prescribed to patients for the treatment and prevention of the following conditions:

  • Herpetic skin rashes;
  • Infection by the herpes simplex virus of the genitals and mucous membranes of the genital tract;
  • Chicken pox;
  • Shingles caused by herpes simplex viruses types 1 and 2.

Contraindications

Acyclovir ointment should not be used for treatment in patients if they have the following symptoms or limitations:

  • Individual intolerance to acyclovir or excipients included in the drug;
  • The presence of purulent or ulcerative lesions on the skin;
  • Open wounds and bacterial skin infection in the affected areas;
  • Children under 3 years of age;
  • Pregnancy and lactation period.

Method of administration and dosage of the drug

This drug is intended for external use for the treatment of herpetic lesions of the skin and external genitalia. The number of daily applications of the ointment and the duration of treatment are determined by the doctor, depending on the diagnosis, the severity of the viral infection, and the individual characteristics of the patient’s body.

For example, to treat a herpes infection around the mouth and under the nose, the ointment should be applied to the affected areas 3 times a day, after cleansing the skin of dust and cosmetics (for women). The course of treatment is at least 5 days.

Treatment of herpes zoster as part of complex therapy with Acyclovir ointment lasts about 7 days, and the drug must be continued to be applied to the affected areas of the skin for another 3 days after the clinical symptoms of the disease disappear in order to prevent relapse of the infection. The total duration of treatment with ointment should not exceed 10 days. If during this period the patient does not observe improvement, then he should consult a doctor again to clarify the correctness of the diagnosis and assess the adequacy of treatment.

Use of the drug during pregnancy and lactation

Doctors do not recommend using Acyclovir anti-herpes ointment in the first 12 weeks of pregnancy. Despite the fact that there is no data on the teratogenic effect of acyclovir on the embryo, the use of this drug during this period is still not recommended, since in the first 3 months the internal organs of the fetus are formed, and the use of any drugs, even local ones, can disrupt this delicate process.

The use of ointment in the 2nd and 3rd trimester should be discussed with a gynecologist. The use of acyclovir during these periods is possible when the expected benefit to the mother is many times greater than the potential risk to the fetus.

The use of Acyclovir ointment during breastfeeding is not recommended, since the active substance of the drug penetrates into breast milk and can accumulate in the baby's body, causing severe impairment of kidney and liver function. If it is necessary to use this drug during lactation, the child should be switched to artificial nutrition with an adapted milk formula.

Side effects and symptoms of drug overdose

Ointment for external use Acyclovir 5% is in most cases well tolerated by patients, however, depending on the individual characteristics of the body and correct use during treatment, the following side effects may develop:

  • Hyperemia and itching of the skin after applying the drug;
  • Burning and allergic skin rashes;
  • Swelling of the skin after applying the drug;
  • Dryness and flaking of the skin with prolonged use or excessive application of the drug.

Since the drug is poorly absorbed into the systemic bloodstream, cases of overdose with acyclovir ointment have not been described in medicine, however, in order to prevent the development of the above side effects, it is not recommended to exceed the dose of the drug prescribed by the doctor.

Interaction of the drug with other drugs

The simultaneous use of Acyclovir ointment with other oral antiviral drugs enhances the therapeutic effect of the ointment.

Simultaneous external use of ointment with Acyclovir tablets increases the risk of side effects if the dosage of the drug is incorrectly calculated.

special instructions

The ointment is intended for external use, therefore Acyclovir 5% cannot be applied to the mucous membrane of the eyes with keratosis, the walls of the vagina, the oral cavity and the nasal mucosa.

Acyclovir ointment does not have a protective effect against genital tract infections, therefore, during treatment with the drug for genital herpes, you must avoid sexual intercourse or use barrier contraception.

The drug is practically not absorbed into the bloodstream, so during treatment with the ointment, the patient can continue to drive a car and operate other complex mechanisms that require reaction speed. The active ingredient of the ointment does not inhibit the functioning of the central nervous system and does not inhibit the reaction rate.

Conditions for storing and dispensing the drug in pharmacies

Acyclovir 5% ointment is available in pharmacies without a prescription. An unopened tube should be stored in a cool place for 2 years from the date of manufacture indicated on the packaging. The opened tube must be stored in the refrigerator or other cold place out of reach of children. Use within a year. After this period has expired, the ointment should be thrown away.

Acyclovir ointment analogs

Analogs for the active substance: Vivorax, Virolex, Gervirax, Herperax, Herpesin, Zovirax, Lisavir, Medovir, Provirsan, Supraviran, Cyclovax, Ciclovir, Citivir.

Acyclovir ointment price

Ointment for external use 5%; aluminum tube 5 g - from 13 rub.

Source: http://bezboleznej.ru/aciklovir-maz

Acyclovir – cream, ointment

keratomas on the face, and after this hot summer everything went wrong in the body. Treat

Cosmetologists don’t have the means. Can I try to use it myself?

glycifol ointment and how to evaluate the reaction? Thanks in advance. Alina

Take these drugs (Hilak-Forte and Biovestin) at different times, with an interval of about 6 hours. Simultaneously does not mean together.

Since the doctor didn’t tell you anything, do a control test 1-2 days after the end of treatment (and, preferably, an additional one six months later). You can begin sexual activity without a condom when tests on both you and your husband show the absence of infection (this means the first test, 2 days after the end of treatment)). However, everything is fine with my husband, congratulations.

The doctor prescribed me Gevisosh ointment (herpes prevention), but I can’t find it in any pharmacy. They say that there is no longer any supply of the drug. Can you tell me if there is an analogue of the drug? Thank you in advance.

Discuss with your doctor the possibility of using these drugs: acyclovir, penciclovir, valacyclovir (Valtrex), famciclovir (famvir).

The information provided is intended for medical and pharmaceutical professionals, should not be used for treatment and cannot be considered as official. The most accurate information about the drug is contained in the instructions supplied with the packaging by the manufacturer. No information posted on this or any other page of our website can serve as a substitute for personal contact with a specialist.

Please pay attention to the specified dates for entering information; information may become outdated.

Source: http://www.webapteka.ru/drugbase/name758_desc268.html

ACICLOVIR OINTMENT INSTRUCTIONS

Prices for ACICLOVIR OINTMENT

Highly active against herpes simplex virus (Herpes simplex) types I and II; the virus that causes chickenpox and herpes zoster (Varicella zoster); Epstein-Barr virus (types of viruses are listed in increasing order of the MIC value of acyclovir). Moderately active against cytomegaloviruses. In case of herpes, it prevents the formation of new rash elements, reduces the likelihood of skin dissemination and visceral complications, accelerates the formation of crusts, and reduces pain in the acute phase of herpes zoster. Has an immunostimulating effect.

Indications for use of the drug Acyclovir ointment are: herpes simplex of the skin; prevention of infections caused by the herpes simplex virus in patients with immune system disorders; genital herpes (primary and recurrent); shingles; chicken pox.

Acyclovir ointment is applied externally.

The ointment is applied to the affected areas of the skin 5 times a day (as soon as possible after the onset of infection). It is important to begin treatment for a recurrent infection during the prodromal phase or at the very beginning of the infection. The course of treatment is at least 5 days, maximum 10 days.

In isolated cases, when using Acyclovir ointment, local irritation of the mucous membranes may occur, which disappears after discontinuation of the drug. With prolonged use of the ointment, some patients may experience peeling of small areas of the skin.

The use of Acyclovir ointment is contraindicated in case of hypersensitivity to the drug.

The use of Acyclovir ointment during pregnancy is possible if the potential benefit to the mother outweighs the possible risk to the fetus.

The drug is found in breast milk after entering the mother's systemic circulation, so breastfeeding should be discontinued during treatment.

Potentiation of the antiviral effect is observed with the simultaneous administration of immunostimulants.

Due to the lack of systemic absorption, an overdose when using the ointment is unlikely.

Store in a dry place, protected from light, at a temperature from +8 °C to +15 °C.

Keep out of the reach of children!

Acyclovir ointment 3, 5 and 10 g in tubes. Each tube, along with instructions for medical use, is placed in a cardboard box.

100 g of Acyclovir ointment contain: acyclovir - 5 g and excipients (chicken oil or refined edible chicken oil or lipid component of poultry fat, polyethylene oxide 400, emulsifier No. 1, nipagin, nipazole, purified water) - up to 100 g.

Reviews ACICLOVIR OINTMENT

All reviews about ACICLOVIR OINTMENT

Analogues of ACICLOVIR OINTMENT

Questions and answers

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Source: http://www.medcentre.com.ua/medicamenty/atsiklovir-maz.html

SYNTHESIS

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Acyclovir

  • Registration number P N001595/01
  • Clinical and pharmacological group Products for external use
  • Pharmacotherapeutic group antiviral agent
  • Trade name Acyclovir
  • International nonproprietary name acyclovir
  • Dosage form ointment for external use
  • Composition 1 g of the drug contains: Active substance – acyclovir – 0.05 g; Excipients: chicken oil (lipid component of poultry fat, LIPOCOMP-S), emulsifier No. 1, propylene glycol, macrogol 400 (polyethylene oxide-400, polyethylene glycol-400), methyl parahydroxybenzoate (nipagin, methylparaben), propyl parahydroxybenzoate (nipazole, propylparaben), purified water up to 1 year
  • ATX code [D06ВВ03]
  • Pharmacological properties Pharmacological action Antiviral (antiherpetic) agent for external use - a synthetic analogue of thymidine nucleoside, which is a natural component of DNA. In infected cells containing viral thymidine kinase, phosphorylation occurs and is converted to acyclovir monophosphate. Under the influence of acyclovir guanylate cyclase, monophosphate is converted into diphosphate and, under the action of several cellular enzymes, into triphosphate. High selectivity of action and low toxicity to humans are due to the absence of the necessary enzyme for the formation of acyclovir triphosphate in intact cells of the macroorganism. Acyclovir triphosphate inhibits the synthesis (replication) of viral DNA by three mechanisms: 1) competitively replaces deoxyguanosine triphosphate in DNA synthesis; 2) “integrates” into the DNA chain being synthesized and stops its elongation; 3) inhibits the DNA polymerase enzyme of viruses. As a result, the reproduction of the virus in the human body is disrupted. The specificity and very high selectivity of action are also due to its predominant accumulation in cells affected by the herpes virus. Highly active against Herpes simplex viruses type 1 and 2; the virus that causes chickenpox and herpes zoster (Varicella zoster); Epstein-Barr virus (types of viruses are listed in increasing order of the minimum inhibitory concentration of acyclovir). Moderately active against cytomegalovirus. In case of herpes, it prevents the formation of new rash elements, reduces the likelihood of skin dissemination and visceral complications, accelerates the formation of crusts, and reduces pain in the acute phase of herpes zoster. Has an immunostimulating effect. Pharmacokinetics When using the ointment on intact skin: absorption is minimal; not detected in blood and urine. Affected skin: absorption is moderate; in patients with normal renal function, the concentration in the blood serum is up to 0.28 mcg/ml, in patients with chronic renal failure – up to 0.78 mcg/ml. Excreted by the kidneys (up to 9.4% of the daily dose).
  • Indications for use Herpes simplex of the skin, genital herpes (primary and recurrent); localized herpes zoster (auxiliary treatment); chicken pox.
  • Contraindications Hypersensitivity to acyclovir or valacyclovir or any other component of the drug.
  • Use during pregnancy is not indicated
  • Directions for use and dosage: Externally.

The ointment is applied to the affected areas 5-6 times a day (as early as possible after the onset of infection) at regular intervals.

It is important to begin treatment for a recurrent infection during the prodromal phase or at the very beginning of the infection.

Therapy should be continued until a crust forms on the blisters or until they are completely healed.

The duration of treatment is at least 5 days, maximum 10 days.

  • Release form

    Ointment for external use 5%

    5 g, 10 g in aluminum or laminate tubes.

    Each tube with instructions for use in a cardboard pack.

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    Source: http://www.kurgansintez.ru/catalog/medicine/atsiklovir_maz_dlya_naruzhnogo_primeneniya_5_/