Antiflu powder instructions for use

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Antiflu powder

Antiflu powder (Pulvis Antiflu)

basic physical and chemical properties: fractionated white powder;

Compound. 1 package includes 650 mg acetaminophen, 10 mg phenylephrine hydrochloride and 4 mg chlorpheniramine maleate;

Table of contents:

other ingredients: ascorbic acid, citric acid, povidone, sodium citrate, natural lemon flavor, starch, stearic acid, FD&C Yellow No. 10, FD&C Yellow No. 6, sucrose, titanium dioxide, calcium triphosphate.

Release form of the medicinal product. Powder.

Pharmacotherapeutic group. Analgesics and antipyretics. ATC code N02BE51.

Pharmacodynamics. Acetaminophen has analgesic, antipyretic, and mild anti-inflammatory effects.

Phenylephrine hydrochloride is an α-adrenergic agonist, which, due to its vasoconstrictor effect, reduces swelling and hyperemia of the mucous membranes of the upper respiratory tract and paranasal sinuses.

Chlorpheniramine maleate is a blocker of H1 - histaminergic receptors; it has an antiallergic effect, eliminates rhinorrhea, lacrimation and itching in the eyes and nose.

Pharmacokinetics. Acetaminophen is metabolized in the liver to form acetaminophen glucuronide and sulfate. The half-life of acetaminophen is 2 - 2.5 hours. It is prolonged in persons with liver disease. Acetaminophen is excreted in the urine (85% of a single dose of acetaminophen is eliminated within 24 hours). Elimination is significantly impaired in cases of impaired renal excretory function, which can lead to accumulation of acetaminophen and its metabolic products in the body.

The half-life of chlorpheniramine maleate is 8 hours. Metabolic products and the unmetabolized part of the drug are excreted in the urine.

Phenylephrine is absorbed and metabolized in the gastrointestinal tract. Phenylephrine is metabolized by monoamine oxidase in the liver and intestines. Metabolites, their role and rate of elimination have not been determined. The pharmacological effect of phenylephrine ends with the absorption of the drug into tissues.
The pharmacokinetics of the drug is determined by the pharmacokinetics of its components.

The components of the drug do not affect each other's pharmacokinetics.

Indications for use. For influenza, acute respiratory viral infections and colds to reduce temperature, eliminate headache and muscle-joint pain, swelling of the mucous membranes of the upper respiratory tract.

Method of use and dose. Before use, dissolve the contents of 1 packet in a glass of hot water. Take 1 packet for adults and children over 12 years old. If necessary, repeat the dose every 4 hours, but no more than 4 packets per day. The total duration of treatment should not exceed 7 days. Subsequent use is only possible under medical supervision.

Side effect. From the central nervous system, drowsiness and sleep disturbances are possible; from the digestive tract - epigastric pain, nausea, vomiting. Allergic reactions may occur (skin rash, itching, swelling); with long-term use - anemia, impaired liver and kidney function.

Contraindications. Increased individual sensitivity to the components of the drug, severe dysfunction of the liver and kidneys. Children from up to 12 years old.

Overdose. May manifest as agitation, dizziness, sleep disturbances, and in severe cases, liver and kidney dysfunction.

Recommended measures: gastric lavage, taking activated carbon or enterosorbent, immediate hospitalization in the toxicology department.

Features of use. Due to the possibility of drowsiness, you should refrain from driving vehicles or operating machinery for 4 hours after taking the drug. In case of arterial hypertension, heart rhythm disturbances, thyrotoxicosis, urinary disorders, pregnancy and breastfeeding, the drug should be taken in consultation with a doctor.

Interaction with other drugs. Acetaminophen, which is part of Antiflu, slows down the removal of antibiotics from the body. The hepato- and nephrotoxicity of acetaminophen increases when combined with barbiturates and alcohol. Tetracyclines increase the risk of anemia and methemoglobinemia when used concomitantly with acetaminophen.

The simultaneous use of Antiflu with sleeping pills, sedatives, antipsychotics, tranquilizers, and alcohol significantly enhances the inhibitory effect of chlorpheniramine maleate on the central nervous system.

Concomitant use of phenylephrine hydrochloride with other adrenergic agonists or monoamine oxidase inhibitors may lead to the development of a hypertensive crisis.

Storage conditions and periods. Store in a dry place, out of reach of children, at a temperature of 15-30°C.

Source: http://polyntrava.ru/lekarstva/analgetiki/antiflu-poroshok.html

Antiflu

Instructions for use:

Prices in online pharmacies:

Antiflu is a medicine intended to eliminate cold symptoms and treat acute respiratory diseases. The drug has analgesic, antipyretic, antiallergic, anti-inflammatory and vasoconstrictor effects.

Release form and composition

Antiflu is available in two forms - film-coated tablets and powder for preparing a solution for drinking.

Each tablet contains 325 mg paracetamol, 5 mg phenylephrine hydrochloride and 2 mg chlorphenamine maleate. The tablets are available in blister packs of 12 pieces (1 blister in 1 cardboard package).

Powder for drinking solution contains paracetamol 650 mg, phenylephrine hydrochloride 10 mg and chlorphenamine maleate 4 mg. There are 5 sachets in the package.

Indications for use

According to the instructions, Antiflu is used for the symptomatic treatment of influenza, colds and ARVI.

Contraindications

The use of Antiflu has the following contraindications:

  • Hypersensitivity to the components of the drug;
  • Kidney failure;
  • Portal hypertension;
  • Alcoholism;
  • Pregnancy;
  • Lactation period;
  • Children's age up to 6 years (for tablets) and up to 12 years (for powder).

The drug should be used with caution in case of angle-closure glaucoma, bronchial asthma, chronic obstructive pulmonary disease, blood diseases, diabetes mellitus, hyperthyroidism, prostate adenoma (if there is a history of difficulty urinating).

Directions for use and dosage

Tablets and powders for preparing hot drinks are taken orally.

According to the instructions for Antiflu, adults and children over 12 years of age are recommended to take 1 tablet every 4 hours (6 times a day), the maximum daily dose is 8 tablets. For children from 6 to 12 years old, the dosage of the drug is calculated according to the child’s body weight (based on the content of paracetamol - mg per 1 kg of weight). Approximately, children from 6 to 12 years old are recommended to take Antiflu 1 tablet 2 times a day with an interval of at least 6 hours.

The drug in powder form should be dissolved in a glass of hot water. Adults and children over 12 years of age can take no more than 4 packets per day.

The duration of taking Antiflu should not exceed 3 days. If there is no desired effect (maintenance of febrile temperature, intoxication), as well as if new symptoms of the disease appear, you should consult a doctor to establish an accurate diagnosis and correct treatment.

Side effects

The use of Antiflu can cause allergic reactions, sleep disturbances, headaches, dizziness, fatigue, nausea, vomiting, dry mouth, and urinary retention.

An overdose of the drug is usually caused by taking an increased dose of paracetamol (more than a day) and has the following manifestations: pale skin, lack of appetite, nausea, vomiting, pain in the upper abdomen. In severe cases, liver failure, encephalopathy and coma may develop. Treatment boils down to gastric lavage, administration of enterosorbents and detoxification therapy.

special instructions

Antiflu enhances the effect of sedatives and ethanol.

Taking the drug together with antidepressants, antiparkinsonian and antipsychotic drugs increases the likelihood of urinary retention, dry mouth and constipation.

The risk of liver toxicity increases when Antiflu is combined with barbiturates, carbamazepine, rifampicin, diphenin, zidovudine.

During the treatment period, you should avoid taking alcohol, sleeping pills and sedatives. You should also refrain from driving and performing work that requires increased concentration.

Antiflu should not be taken with other drugs containing paracetamol. If there is no effect of treatment within 3 days, you should consult a doctor.

Analogs

Structural analogues of Antiflu are the drugs Anakold and Theraflu Extratab.

Storage conditions and periods

The drug should be stored in a dry place at air temperature °C. Keep away from children.

Shelf life – 3 years from the date of production.

AntiFlu Kids No. 5 sachets

Antiflu kids por. d/r-ra internal 12g n5

AntiFlu Kids powder 12 g 5 pcs.

Antiflu Kids powder for preparing solution N5

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Source: http://www.neboleem.net/antiflu.php

Antiflu

Description current as of 06/10/2015

  • Latin name: Antiflu
  • ATX code: N02BE51
  • Active ingredient: Phenylephrine, Paracetamol, Chlorphenamine
  • Manufacturer: Sagmel, Inc. (USA)

Compound

Antiflu contains active substances such as acetaminophen, chlorpheniramine maleate, phenylephrine hydrochloride.

Additional components of the tablets: colloidal silicon dioxide, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, hydroxypropyl methylcellulose, magnesium silicate. The shell consists of polyethylene glycol, yellow dye and mineral oil.

The powder includes the following auxiliary components: tribasic calcium phosphate, ascorbic and citric acid, silicon dioxide, lemon flavor, tribasic sodium citrate, sucrose, yellow dye, starch, titanium dioxide.

Release form

Powder for preparing solution and tablets.

pharmachologic effect

Antiflu is a combined drug that acts as an antipyretic, anti-inflammatory, analgesic, antiallergic, and vasoconstrictor drug.

Pharmacodynamics and pharmacokinetics

The peculiarities of the medicine's action are determined by the components included in its composition. It acts as an antipyretic, vasoconstrictor, alpha-adrenergic stimulant and antihistamine.

The product begins to act minutes after application. The effect lasts 4-4.5 hours.

Indications for use

Contraindications

Side effects

With long-term therapy in high dosages, aplastic or hemolytic anemia, hepatotoxicity, pancytopenia, methemoglobinemia, and nephrotoxicity are observed.

Instructions for use of Antiflu (Method and dosage)

The instructions for Antiflu tablets indicate that adult patients and children over 12 years of age should take one tablet every 4 hours. The maximum daily dosage should not exceed 8 tablets.

For children under 12 years of age, the exact dose is calculated individually based on body weight. They give mg per 1 kg of weight. The interval between doses is at least 6 hours.

Usually the course of treatment does not exceed three days. Instructions for use of Antiflu indicate that it is a symptomatic medication. If no improvement is observed while taking it, it is advisable to contact a specialist to adjust the application regimen.

The powdered medicine should be taken every 4 hours, one sachet. The daily dose should not exceed 4 sachets. The powder is pre-dissolved in a glass of warm water to obtain a solution that is used internally. You should not take the drug for more than three days.

Overdose

In case of overdose, increased pallor, nausea, decreased appetite, vomiting, increased activity of liver transaminases, hepatonecrosis, and increased prothrombin time are observed.

If the medication is taken in high doses, gastric lavage is performed in the first six hours, after 8-9 hours, precursors for the synthesis of Glutathione-Methionine and SH-group donors are introduced.

Interaction

It is not recommended to take the medicine at the same time with MAO inhibitors and drugs including Paracetamol. Combination with sedative medications and ethanol worsens their effect. And when taken with antidepressants, antipsychotics and antiparkinsonian drugs, the likelihood of adverse reactions such as constipation, dry mouth and urinary retention increases.

During therapy, you should avoid alcohol, tranquilizers and sleeping pills.

Terms of sale

The medicine is approved for over-the-counter release.

Storage conditions

The product must be kept away from small children. The storage temperature of the drug is 15–25°C.

Best before date

Reviews

On the Internet you can find both negative and positive reviews about this drug. Most of them say that the remedy helped cope with unwanted symptoms of the disease in the shortest possible time. But many decide to take it only as a last resort, as they fear adverse effects on the body.

Some patients describe that after an overdose of the drug they experienced vomiting, nausea and pain in the epigastric region.

Antiflu price, where to buy

The price of Antiflu in pharmacies can vary greatly. On average, this product costs about 200 rubles. However, in some pharmacies the price of Antiflu reaches 240 rubles or is reduced to 80 rubles.

  • Online pharmacies in Russia Russia
  • Online pharmacies in Ukraine Ukraine
  • Online pharmacies in Kazakhstan Kazakhstan

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All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://medside.ru/antiflu

Antiflu powder - official instructions for use

on medical use of the drug

Registration number:

Trade name of the drug:

Dosage form:

Compound:

Excipients: ascorbic acid, citric acid, silicon dioxide, natural lemon flavor, tribasic sodium citrate, starch, sucrose, titanium dioxide, tribasic calcium phosphate, FD&C yellow dye 10, FD&C yellow dye 6.

Description. A mixture of white and yellow crystalline powders with a faint lemon odor.

Pharmacotherapeutic group.

Pharmachologic effect.

Indications for use.

Contraindications.

used for: arterial hypertension, severe cardiovascular diseases, diabetes mellitus, bronchial asthma, chronic obstructive pulmonary disease, thyrotoxicosis, pheochromocytoma, closed-angle glaucoma, severe liver or kidney diseases, difficulty urinating with prostate adenoma, blood diseases, congenital hyperbilirubinemia (syndromes) Gilbert, Dubin-Johnson and Rother).

Method of administration and dose.

The duration of treatment is no more than 3 days. If there is no sufficient therapeutic effect, there is a high temperature that persists during treatment for more than 3 days, or new symptoms appear, consult a doctor immediately.

Side effects.

Considering the presence of paracetamol: rarely - disorders of the hematopoietic system (anemia, thrombocytopenia, leukopenia, agranulocytosis); with long-term use of high doses, hepatotoxic and nephrotoxic effects, hemolytic anemia, methemoglobinemia, and pancytopenia are possible.

Overdose:

Treatment: gastric lavage, activated carbon in the first 6 hours, administration of SH-group donors and precursors for the synthesis of glutathione - methionine 8-9 hours after an overdose and N-acetyl cysteine ​​after 12 hours.

Interaction with other drugs.

It is recommended to refrain from taking the drug when taking monoamine oxidase inhibitors. The risk of hepatotoxic action of paracetamol increases with the simultaneous administration of barbiturates, diphenine, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes. Strengthens the effect of sedatives and ethanol. Ethanol enhances the sedative effect of chlorpheniramine. Antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of developing urinary retention, dry mouth, and constipation.

Special instructions.

Release form.

Storage conditions.

Best before date.

Vacation conditions.

Manufacturer.

Representative office in Russia:

Source: http://medi.ru/instrukciya/antiflu-poroshok_9891/

ANTIFLUE KIDS, POWDER (BAGS)

Instructions for medical use

International nonproprietary name

Raspberry flavored powder

1 sachet contains

active ingredients - acetaminophen 160 mg, ascorbic acid 50 mg, chlorpheniramine maleate 1 mg;

excipients - sugar (powdered sugar), sugar (sucrose), raspberry flavor, citric acid, silicon dioxide, silicon dioxide (syloid), tribasic sodium citrate (trisodium citrate dihydrate), titanium dioxide (E 171), tricalcium phosphate (calcium phosphate tribasic), corn starch, red dye FD&C No. 40 (E 129).

Analgesics. Other analgesics and antipyretics. Anilides. Paracetamol in combination with other drugs (excluding psycholeptics).

ATX code N02BE51

Acetaminophen (paracetamol) is absorbed in the upper intestine by passive diffusion; the half-life (T½) of acetaminophen is 2-2.5 hours. It is prolonged after taking large doses and in persons with liver disease. Acetaminophen is excreted in the urine (85% of a single dose of acetaminophen is eliminated within 24 hours).

Chlorpheniramine maleate is absorbed in the small intestine and undergoes biotransformation in the liver. The half-life of elimination is 8 hours. Metabolic products and the unmetabolized part of the drug are excreted in the urine.

Ascorbic acid is actively absorbed in the small intestine. The maximum concentration in plasma after oral administration is reached after 4 hours. From plasma it easily penetrates into leukocytes, platelets and almost all tissues. Elimination of ascorbic acid occurs both through its excretion unchanged in the urine and through biotransformation into deoxyascorbic and diketogulonic acids (the latter is converted into oxalic acid), excreted in the urine.

Acetaminophen (paracetamol) has an analgesic, antipyretic and mild anti-inflammatory effect due to its effect on the thermoregulation center and inhibition of prostaglandin synthesis in the central nervous system.

Chlorpheniramine maleate is an H1-histamine receptor blocker that interferes with the action of one of the main mediators of inflammation - histamine.

By reducing the permeability of capillary walls, it reduces the severity of local exudative manifestations, swelling of the mucous membranes of the nose, nasopharynx, upper respiratory tract, and lacrimation.

Ascorbic acid (Vitamin C) has antioxidant properties, activates defense mechanisms, increases the body's resistance to infection. Activates redox processes, stimulates regeneration processes, synthesis of glucocorticoids and catecholamines; compacts the capillary wall (by increasing the formation of intercellular substance and reducing the activity of hyaluronidase).

Antiflu ® Kids reduces headaches, muscle-joint pain, sore throat, eliminates rhinorrhea, itching in the eyes and nose.

Children from 2 to 12 years old

To eliminate the symptoms of ARVI, flu and colds:

- increased body temperature, chills

- nasal congestion, sneezing

- headache and muscle-joint pain

- sore throat and other symptoms of inflammation of the upper respiratory tract and paranasal sinuses.

Directions for use and doses

Take orally, regardless of meals. Before use, dissolve the contents of one packet in 150 ml of warm water. A single dose for children 2-6 years old is the contents of 1 sachet, for children 6-12 years old - the contents of 2 sachets. If necessary, repeat the dose every 4-6 hours, but not more than 4 doses. The course of treatment is 5 days. Further use is possible only under medical supervision.

In most cases, the drug is well tolerated.

The following side effects may occur:

Disorders of the hematopoietic and lymphatic system:

Anemia, sulfhemoglobinemia and methemoglobinemia (cyanosis, shortness of breath, heart pain), hemolytic anemia (if the patient suffers from glucose-6-phosphate dehydrogenase deficiency), thrombocytopenia, leukopenia

Nausea, pain in the epigastric region.

Increased activity of liver enzymes (usually without jaundice), liver necrosis (dose-dependent effect).

From the immune system:

Hypersensitivity reactions, including angioedema, anaphylactic shock.

Nervous system disorders:

Drowsiness headache.

Renal and urinary tract disorders:

Renal colic and interstitial nephritis, urinary retention, aseptic pyuria, with long-term use in high doses - damage to the glomerular apparatus of the kidneys, formation of stones in the kidneys.

Diseases of the skin and subcutaneous tissue:

Itching, rash on the skin and mucous membranes (erythema, urticaria), erythema multiforme (including Stevens-Johnson syndrome) and toxic epidermal necrolysis (Lyell's syndrome).

  • increased individual sensitivity to the components of the drug
  • severe liver and/or kidney dysfunction
  • deficiency of the enzyme glucose-6-phosphate dehydrogenase
  • Gilbert's syndrome
  • hematopoietic disorders
  • fructose intolerance, glucose/galactose malabsorption or sucrase-isomaltase deficiency
  • children under 2 years old

The drug should not be used simultaneously with other paracetamol-containing drugs.

Acetaminophen slows down the removal of antibiotics from the body. The hepato- and nephrotoxicity of acetaminophen increases when combined with barbiturates. Tetracyclines increase the risk of anemia and methemoglobinemia with acetaminophen use.

The simultaneous use of hypnotics and sedatives, neuroleptics and tranquilizers significantly enhances the inhibitory effect of chlorpheniramine maleate on the central nervous system.

It is not recommended to use simultaneously with sedatives and hypnotics.

The medicine should be taken in the following cases only after a doctor has assessed the risk-benefit ratio:

  • arterial hypertension
  • diabetes
  • epilepsy
  • heart rhythm disturbances
  • thyrotoxicosis
  • urinary disorders
  • oxalaturia
  • viral hepatitis.

Pregnancy and lactation

Paracetamol and ascorbic acid may distort laboratory tests (quantitative determination of glucose and uric acid in plasma).

Each sachet contains 11.59 g of sucrose, which must be taken into account when consumed daily if you are on a low-sugar diet or have diabetes.

Features of the effect of the drug on the ability to drive vehicles or potentially dangerous mechanisms

Given the drug’s ability to cause drowsiness, children should be kept from activities that require increased concentration for 4 hours after administration.

Symptoms of paracetamol overdose: in the first 24 hours, pallor, nausea, vomiting, anorexia and abdominal pain. In case of overdose, agitation, dizziness, and sleep disturbances may occur.

There have been reports of isolated cases of acute renal failure following an overdose of paracetamol.

In severe cases, liver damage (hepatocellular necrosis) and liver dysfunction may occur and may progress to encephalopathy, hepatic coma and death. Clinical signs of liver damage may not appear for 12 to 48 hours after an overdose. Impaired glucose metabolism and metabolic acidosis may occur. Liver failure may develop after use of more than 150 mg/kg.

Treatment: gastric lavage during the first 6 hours after an overdose of paracetamol. Cytotoxic effects can be reduced by oral methionine or intravenous N-acetylcysteine ​​within eight hours of overdose.

Release form and packaging

The powder is hermetically packaged in a bag made of laminated material (paper/polyethylene/foil/polyethylene). 5 sachets together with instructions for medical use in the state and Russian languages ​​are placed in a cardboard box.

Store at a temperature not exceeding 25°C.

Keep out of the reach of children!

Do not use after the expiration date stated on the packaging.

Conditions for dispensing from pharmacies

Name and country of the manufacturing organization

Contract Pharmacal Corporation,

135 Adams Avenue, Hope, New York 11788, USA

Name and country of the marketing authorization holder

Bayer Consumer Care AG, Switzerland

Address of the organization that accepts claims from consumers regarding the quality of products (goods) in the territory of the Republic of Kazakhstan and is responsible for post-registration monitoring of the safety of the medicinal product:

St. Timiryazeva, 42, Expo City business center, pav. 15

Almaty, Republic of Kazakhstan

Tel: – 24 hours a day

Tel.: (106) – during business hours

Fax machine:

All rights reserved and protected by law,

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Source: http://pharmprice.kz/annotations/antiflu-kids/

Antiflu powder: instructions for use

Compound

Acetaminophen 650 mg, phenylephrine hydrochloride 10 mg, chlorpheniramine mapeate 4 mg.

Inactive ingredients: ascorbic acid, sugar, citric acid, silicon dioxide, lemon flavor, sodium citrate tribasic, starch, titanium dioxide, tricalcium phosphate, colors: P&C Yellow No. 10, PO&C Yellow No. 6.

Description

pharmachologic effect

Acetaminophen (paracetamol) has an analgesic, antipyretic and mild anti-inflammatory effect. Reduces headache, muscle and joint pain, sore throat. Chlorpheniramine maleate has an antihistamine effect: it eliminates swelling of the mucous membranes of the nose, nasopharynx, and upper respiratory tract, and reduces itching of the eyes.

Phenylephrine hydrochloride has a vasoconstrictor effect, reduces swelling and hyperemia of the mucous membrane of the nose and nasopharynx, facilitating nasal breathing.

Indications for use

Contraindications

Directions for use and doses

Side effect

From the gastrointestinal tract: epigastric pain, nausea, vomiting. With long-term use of the drug together with alcohol, the development of hepatotoxicity is possible.

From the side of the central nervous system: drowsiness, sleep disturbances, increased excitability (especially in children). Allergic reactions: skin rash, itching, Quincke's edema.

From the hematopoietic system: anemia, thrombocytopenia.

Overdose

Interaction with other drugs

It is not recommended to take simultaneously with sleeping pills, sedatives and drugs containing alcohol.

The hepato- and nephrotoxicity of acetaminophen increases when combined with barbiturates and alcohol.

The simultaneous use of sleeping pills and sedatives, antipsychotics, tranquilizers, and alcohol significantly enhances the inhibitory effect of chlorpheniramine maleate on the central nervous system.

Acetaminophen slows down the removal of antibiotics from the body. Tetracyclines increase the risk of anemia and methemoglobinemia with acetaminophen use.

Phenylephrine hydrochloride weakens the hypotensive effect of reserpine and ocgadine. The combined use of monoamine oxidase inhibitors and phenylephrine hydrochloride can lead to the development of a hypertensive crisis.

Features of application

Release form

Storage conditions

Best before date

Conditions for dispensing from pharmacies

Antiflu powder analogues, synonyms and group drugs

You should consult your doctor and read the instructions before use.

Source: http://apteka.103.by/antiflu-instruktsiya/

ANTIFLUE

◊ Powder for the preparation of a solution for oral administration in the form of a mixture of crystalline powders of white or yellow color with a faint odor of lemon.

Excipients: ascorbic acid, citric acid, silicon dioxide, natural lemon flavor, tribasic sodium citrate, starch, sucrose, titanium dioxide, tribasic calcium phosphate, FD&C yellow 10, FD&C yellow 6.

17 g - laminated foil bags (5) - cardboard packs.

Paracetamol has an analgesic, antipyretic and mild anti-inflammatory effect.

Phenylephrine hydrochloride, an alpha-adrenergic agonist, has a vasoconstrictor effect, reduces swelling and hyperemia of the nasal mucosa and paranasal sinuses.

Chlorphenamine maleate is a histamine H1 receptor . It has an antiallergic effect, reduces the severity of local exudative manifestations, eliminates lacrimation, itching in the eyes and nose.

Symptomatic treatment of colds, flu, ARVI:

- hypersensitivity to individual components of the drug;

- period of breastfeeding;

Do not use in children under 12 years of age.

with caution in case of arterial hypertension, severe cardiovascular diseases, diabetes mellitus, bronchial asthma, chronic obstructive pulmonary disease, thyrotoxicosis, pheochromocytoma, closed-angle glaucoma, severe liver or kidney diseases, difficulty urinating with prostate adenoma, blood diseases, congenital hyperbilirubinemia ( syndromes of Gilbert, Dubin-Johnson and Rother).

Inside. Adults and children over 12 years of age are prescribed 1 sachet every 4 hours, but not more than 4 sachets per day.

Before use, the contents of 1 sachet must be dissolved in a glass of hot water.

The duration of treatment is no more than 3 days.

The patient must be warned that in the absence of a sufficient therapeutic effect, the presence of a high temperature that persists during treatment for more than 3 days, or the appearance of new symptoms, he should immediately consult a doctor.

Possible allergic reactions (rash, itching, urticaria, angioedema), increased excitability (especially in children), sleep disturbances, drowsiness, decreased speed of psychomotor reactions, feeling tired, nausea, vomiting, stomach pain, palpitations, increased blood pressure, dizziness, mydriasis, accommodation paresis, increased intraocular pressure, dry mouth, urinary retention.

Considering the presence of paracetamol : rarely - disorders of the hematopoietic system (anemia, thrombocytopenia, leukopenia, agranulocytosis); with long-term use of high doses, hepatotoxic and nephrotoxic effects, hemolytic anemia, methemoglobinemia, and pancytopenia are possible.

Caused, as a rule, by paracetamol, it manifests itself after taking more than the latter.

Possible : pallor of the skin, anorexia, nausea, vomiting, pain in the epigastric region, increased activity of liver transaminases, increased prothrombin time, hepatotoxic and nephrotoxic effects, in severe cases liver failure, encephalopathy and coma develop.

Treatment : gastric lavage, intake of activated carbon in the first 6 hours, administration of SH-group donors and precursors for the synthesis of glutathione-methionine 8-9 hours after an overdose and N-acetylcysteine ​​- after 12 hours.

It is recommended to refrain from taking the drug when taking MAO inhibitors.

The risk of hepatotoxic action of paracetamol increases with simultaneous use of barbiturates, diphenine, carbamazepine, rifampicin, zidovudine and other inducers of microsomal liver enzymes.

Strengthens the effect of sedatives and ethanol. Ethanol enhances the sedative effect of chlorphenamine.

Antidepressants, antiparkinsonian and antipsychotic drugs, phenothiazine derivatives increase the risk of developing urinary retention, dry mouth, and constipation.

During the treatment period, you should refrain from taking alcohol, sleeping pills and anxiolytic (tranquilizers) medications.

Do not take with other medicines containing paracetamol.

If symptoms do not go away within 3-5 days, consult a doctor.

Impact on the ability to drive vehicles and operate machinery

During the treatment period, you should avoid driving vehicles, operating machinery and other potentially hazardous activities.

Store in a dry place, out of reach of children, at a temperature of 15° to 25°C.

Shelf life: 3 years. Do not use after expiration date.

To ask a question about the project or contact the editors, use this form.

Source: http://health.mail.ru/drug/antiflu/

AntiFlu Kids (children)

Many mothers encounter colds or flu in their children every year, so medications that alleviate the condition of a sneezing, coughing and feverish baby are in great demand. One such medicine can be called Antiflu Kids. What does it contain, how does this drug work and in what dose is it used in childhood?

Release form

Antiflu Kids is available in powder, from which an oral solution is prepared. The medicine has a white tint and is represented by loose crystals that smell like raspberries. They are packaged in portioned bags weighing 12 grams. One pack contains 5 or 8 sachets. After adding water to the Antiflu Kids powder, a pale pink, opaque liquid is obtained, which also has a pleasant raspberry smell.

Compound

Each Antiflu Kids package contains the following three main ingredients:

  • Paracetamol. One package contains 160 mg.
  • Chlorphenamine maleate. This compound comes in a dosage of 1 mg per packet.
  • Ascorbic acid. Its content in each package is 50 mg.

Additional components in Antiflu Kids powder are red dye, raspberry flavor, titanium dioxide, corn starch, Na citrate, Si dioxide, powdered sugar, Ca phosphate, citric acid and sucrose.

You may be interested in listening to what Dr. Evgeniy Komarovsky says about the treatment of ARVI and influenza in children:

Operating principle

Antiflu for children is a combination medicine, because it contains several active compounds:

  • Paracetamol is an analgesic that has a fairly good antipyretic effect and a slight anti-inflammatory effect.
  • The main effect of chlorphenamine maleate is to block histamine-sensitive receptors. Thanks to this, Antiflu Kids has an anti-allergic effect, which helps cope with symptoms such as itching in the nasal cavity and eyes, runny nose or lacrimation.
  • Ascorbic acid has the property of increasing resistance to infectious agents. In addition, this vitamin has a positive effect on paracetamol tolerance.

Taking Antiflu for children quickly helps to reduce body temperature, eliminate muscle pain and headaches, as well as sore throat. The medicine also effectively fights rhinitis.

Indications

The main reason to give Antiflu Kids to young patients is a cold, acute respiratory infection or flu. The medicine is prescribed for severe runny nose, sore throat, fever, sneezing, headache, myalgia and other symptoms of ARVI.

At what age is it allowed to take it?

The age limit for taking Antiflu Kids is 2 years. If the child is not yet two years old, he should not be given this drug.

Contraindications

Instructions for use for children prohibit Antiflu for children when:

  • Hypersensitivity to any of its ingredients.
  • Severe renal dysfunction.
  • Serious problems with liver function.

Side effects

The most common negative actions provoked by Antiflu Kids are drowsiness and inhibited reaction. For this reason, within four hours after the child has taken the medicine, there is no need to give him tasks that require increased activity and concentration.

Rare side effects from taking children's Antiflu are:

Instructions for use and dosage

Antiflu Kids must be taken orally, and there is no effect of food intake on this medicine. The contents of the sachet are stirred in warm water taken in a volume of approximately 150 ml. For a child aged from two to 5 years, one packet of Antiflu Kids is considered a single dose. If the child is already 6 years old, then it is recommended to give him the contents of two packages at one time.

If required, the drug is repeated with a pause of 4 to 6 hours, but the daily dosage should not exceed 3 packets for children 2-5 years old and 6 packets for children over 6 years old.

Antiflu Kids treatment can be carried out for five days. If the child has not recovered during this time, you should consult your doctor about continuing to use the drug.

Overdose

Too high a dose of Antiflu Kids can worsen the functioning of the kidneys and liver. And therefore, if a child is accidentally given medication in an amount greater than that recommended for age, you should immediately contact a specialist.

Interaction with other drugs

You should not combine treatment with Antiflu Kids and the use of sedatives or sleeping pills. You should also not take children's Antiflu and medications that contain ethanol at the same time.

Terms of sale

To buy Antiflu Kids at a pharmacy, you do not need a prescription from a pediatrician. The average price of a package with 5 sachets of this drug is 200 rubles.

Storage conditions and shelf life

The place where Antiflu Kids sachets will be stored should be inaccessible to small children. It should also be dry, and the optimal temperature for storing this medicine is called the range +15+30°C.

Antiflu Kids should be used before its expiration date, which is three years. It is recommended to drink the solution prepared from the powder immediately, although if necessary it can be left for several hours.

Reviews

Mothers generally leave good reviews about the use of Antiflu Kids in children with ARVI. They note a fairly quick effect of the medicine (the temperature drops within minutes after administration) and a pleasant taste, which children often do not protest against. Adverse reactions to this medication are rare.

Analogs

Instead of Antiflu Kids, Antigrippin can be used, since this analogue has the same active ingredients. However, they are presented in a higher dose, so this medicine is approved only from the age of 15.

The following medications with similar effects can serve as a substitute for Antiflu Kids for a child:

  • Fervex for children. This drug, containing paracetamol, ascorbic acid and pheniramine, is also available in powder, packaged in separate sachets. The medicine is prescribed from the age of 6 years.
  • Efferalgan with vitamin C. The basis of this medicine is a combination of ascorbic acid and paracetamol. The product is presented in effervescent tablets, approved for children over 8 years of age.
  • Coldrex Junior Hot drink. The main components of this product are phenylephrine, vitamin C and paracetamol. The medicine comes in sachets, the contents of which are mixed with hot water to produce a yellow lemon drink. The drug is given to children over six years of age.

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Antiflu

Prices in online pharmacies:

Antiflu is a drug used in the treatment of ARVI, influenza and colds.

Release form and composition

Antiflu is produced in the form of oval light yellow biconvex film-coated tablets, on one side of which there is an engraving “Antiflu”, in blisters of 12 pcs.

One tablet contains 325 mg of paracetamol, 5 mg of phenylephrine hydrochloride, 2 mg of chlorphenamine maleate and excipients - colloidal silicon dioxide, microcrystalline cellulose, magnesium stearate, stearic acid, magnesium silicate, hydroxypropyl methylcellulose and croscarmellose sodium. The film shell contains mineral oil and polyethylene glycol.

They also produce Antiflu powder, intended for the preparation of a solution taken orally, which looks like a mixture of crystalline powders of yellow and white color, and has a lemon smell, in 17 g laminated foil bags.

One sachet of Antiflu powder contains 650 mg of paracetamol, 10 mg of phenylephrine hydrochloride, 4 mg of chlorphenamine maleate and excipients - ascorbic and citric acid, FD&C yellow 10 and FD&C yellow 6 dye, natural lemon flavor, starch, tribasic calcium phosphate, silicon dioxide, sodium citrate tribasic, sucrose and titanium dioxide.

Indications for use of Antiflu

In accordance with the instructions, Antiflu is prescribed for the symptomatic treatment of ARVI, influenza and colds.

Contraindications

The use of Antiflu is contraindicated in cases of hypersensitivity to the components of the drug, alcoholism, pregnancy, renal failure and portal hypertension. The drug is not prescribed for glucose-6-phosphate dehydrogenase deficiency, during lactation and for children under 6 years of age.

Method of use and dosage of Antiflu

The drug in the form of tablets is taken orally by children over 12 years of age and adults every 4 hours, 1 piece. The maximum dose is 8 tablets per day.

For children from six to 12 years old, a single dose is determined based on the proportion of paracetamol per 1 kg of body weight, on average 1-2 tablets are prescribed, taken every 6 hours.

Antiflu powder must be diluted in 250 ml of hot water before use. The dosage of the product is 1 sachet every four hours, a maximum of 4 pieces per day is allowed.

The course of therapy for both forms of Antiflu should not exceed 3 days; if there is no sufficient therapeutic effect during this period, you should consult a doctor.

Side effects of Antiflu

In accordance with the instructions, Antiflu can cause allergic reactions, sleep disturbances, increased excitability, fatigue, stomach pain, nausea and vomiting. Also, the drug in some cases reduces the speed of psychomotor reactions, increases intraocular pressure, causes drowsiness, increased blood pressure, dry mouth, mydriasis, urinary retention, palpitations, accommodation paresis and dizziness.

In cases of overdose of Antiflu, anorexia, pallor of the skin, pain in the epigastric region, encephalopathy, liver failure, nausea, vomiting, increased prothrombin time and coma may occur. In such cases, gastric lavage and appropriate symptomatic treatment are required.

special instructions

During the period of use of Antiflu, it is recommended to avoid taking other paracetamol-containing, anxiolytic and hypnotic drugs, as well as alcoholic beverages.

The medication affects the patient’s ability to drive vehicles and complex machinery.

Antiflu's analogs

Synonyms for the drug include the drugs Coldact Flu Plus and TheraFlu Extratab.

Analogues of Antiflu with the same mechanism of action, as well as belonging to the same pharmacological group, are drugs such as:

Terms and conditions of storage

In accordance with the instructions, Antiflu should be stored in a well-ventilated, dry place, protected from light and out of reach of children, at a temperature varying within °C. The medication is dispensed from pharmacies without a prescription; its shelf life, provided all manufacturer's recommendations are followed, is three years. After the expiration date, the medicinal product must be disposed of.

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