Zinnat how to take

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Zinnat - instructions for use, reviews, analogs and release forms (tablets 125 mg and 250 mg, granules for preparing an antibiotic suspension) medications for the treatment of sore throat, pyelonephritis, bronchitis in adults, children and pregnancy

In this article you can read the instructions for use of the drug Zinnat.

Table of contents:

Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of the antibiotic Zinnat in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Zinnat in the presence of existing structural analogues. Use for the treatment of sore throat, pyelonephritis, bronchitis and other infections in adults, children, as well as during pregnancy and lactation.

Zinnat is a 2nd generation cephalosporin antibiotic for parenteral use. It has a bactericidal effect and disrupts the synthesis of bacterial cell walls. Has a wide spectrum of action.

Resistant to most beta-lactamases.

Cefuroxime (the active substance of the antibiotic Zinnat) is highly active against aerobic gram-positive bacteria: Staphylococcus aureus, Staphylococcus epidermidis (including strains resistant to penicillins and with the exception of rare methicillin-resistant strains), Streptococcus pyogenes (and other beta-hemolytic streptococci), Streptococcus pneumoniae, Streptococcus group B (Streptococcus agalactiae), Streptococcus mitis (viridans group), Bordetella pertusis; aerobic gram-negative bacteria: Escherichia coli, Klebsiella spp., Proteus mirabilis, Providencia spp., Proteus rettgeri, Haemophilus influenzae (including ampicillin-resistant strains), Haemophilus parainfluenzae (including ampicillin-resistant strains), Moraxella (Branhamella) catarrhalis, Neisseria gonorrhoeae ( including strains producing and not producing penicillinase), Neisseria meningitidis, Salmonella spp.; anaerobic gram-positive bacteria: Peptococcus spp., Peptostreptococcus spp., Clostridium spp., Propionibacterium spp.; anaerobic gram-negative bacteria: Bacteroides spp, Fusobacterium spp.; also active against Borrelia burgdorferi.

Clostridium difficile, Pseudomonas spp., Campylobacter spp., Acinetobacter calcoaceticus, Listeria monocytogenes, methicillin-resistant strains of Staphylococcus aureus, methicillin-resistant strains of Staphylococcus epidermidis, Legionella spp. are resistant to cefuroxime.

Studies have shown that when cefuroxime is combined with aminoglycoside antibiotics, an additive effect is observed, and in some cases, synergism.

Cefuroxime (in the form of cefuroxime axetil) + excipients.

After oral administration, Zinnat is absorbed from the gastrointestinal tract and is rapidly hydrolyzed in the intestinal mucosa and blood, releasing cefuroxime into the systemic circulation. Food accelerates the absorption of cefuroxime axetil suspension. When taking a suspension, the rate of absorption of cefuroxime axetil is lower than when taking tablets. Cefuroxime is not biotransformed in the body and is excreted unchanged by the kidneys through glomerular filtration and tubular secretion.

Treatment of infectious and inflammatory diseases caused by microorganisms sensitive to the drug:

  • respiratory tract infections (including acute and chronic bronchitis, infected bronchiectasis, bacterial pneumonia, lung abscess, postoperative chest infections);
  • infections of the ear, throat, nose (including sinusitis, tonsillitis, pharyngitis, acute otitis media);
  • infections of the genitourinary system (including acute and chronic pyelonephritis, cystitis, urethritis, asymptomatic bacteriuria);
  • infections of the skin and soft tissues (including furunculosis, pyoderma, impetigo);
  • gonorrhea (including acute uncomplicated gonococcal urethritis and cervicitis);
  • treatment of Lyme disease at an early stage and subsequent prevention of late manifestations in adults and children over 12 years of age.

Film-coated tablets 125 mg and 250 mg.

Granules for the preparation of a suspension for oral administration (sometimes mistakenly called syrup).

Instructions for use and dosage

For adults, the average single dose is 250 mg, the frequency of administration is 2 times a day.

For severe infections of the lower respiratory tract, 500 mg is prescribed 2 times a day; for mild to moderate infections - 250 mg 2 times a day.

For urinary tract infections, 125 mg is prescribed 2 times a day, for pyelonephritis - 250 mg 2 times a day.

For the treatment of uncomplicated gonorrhea, 1 g is prescribed once.

For Lyme disease, adults and children over 12 years of age - 500 mg 2 times a day for 20 days.

Children under 12 years of age can be prescribed the drug in the form of a suspension. The average dose for children for most infections is 1 tablet (125 mg) 2 times a day. For severe infections or otitis media in children aged 2 years and older, the average dose is 1 tablet (250 mg) or 2 tablets (125 mg) 2 times a day.

For infectious diseases of mild to moderate severity, a single dose is set at the rate of 10 mg/kg body weight.

For otitis media and severe infections, a single dose is set at 15 mg/kg. The frequency of administration is 2 times a day.

The maximum daily dose is 500 mg.

The average duration of use of the drug is 7 days (5-10 days).

It is recommended to take the drug after meals.

  • nausea, vomiting;
  • diarrhea;
  • jaundice;
  • cases of pseudomembranous colitis have been described;
  • hemolytic anemia, eosinophilia, neutropenia, thrombocytopenia, leukopenia;
  • skin rash;
  • itching;
  • hives;
  • fever;
  • erythema multiforme;
  • Stevens-Johnson syndrome;
  • toxic epidermal necrolysis;
  • serum sickness;
  • anaphylaxis;
  • headache;
  • positive Coombs reaction.
  • hypersensitivity to cephalosporin antibiotics.

Use during pregnancy and breastfeeding

Zinnat is used with caution in the 1st trimester of pregnancy and during lactation.

Experimental studies have not established the embryotoxic and teratogenic effects of Zinnat.

Can be used in children from 3 months of age.

Zinnat is prescribed with extreme caution to patients with hypersensitivity to penicillin antibiotics, because There are reports of cases of cross-allergic reactions.

With long-term use of Zinnat, increased growth of resistant microorganisms (Candida, Enterococci, Clostridium difficile) is possible, which may require discontinuation of treatment.

When diarrhea occurs due to the use of antibiotics, incl. Zinnat, one should keep in mind the possibility of developing pseudomembranous colitis.

When treating Lyme disease with Zinnat, a Jarisch-Gersheimer reaction is sometimes observed. This reaction is a direct consequence of the bactericidal effect of Zinnat on the causative agent of the disease - the spirochete Borrelia burgdorferi. Patients should be advised that this is a common and normal consequence of antibiotic treatment for Lyme disease.

When prescribing Zinnat to patients with diabetes mellitus, the presence of sucrose in the suspension should be taken into account.

Since the potassium iron sulfide test may give a false-negative result in patients receiving cefuroxime axetil, the use of glucose oxidase or hexokinase methods is recommended to determine blood glucose levels. Cefuroxime does not affect the results of determining creatinine levels using alkali and picric acid.

Granules or prepared suspension must not be mixed with hot liquids.

Co-administration of cefuroxime and probenecid results in an increase in the AUC of cefuroxime by 50%.

When used simultaneously, antacids may reduce the bioavailability of Zinnat in suspension form.

Analogues of the drug Zinnat

Structural analogues of the active substance:

Source: http://instrukciya-otzyvy.ru/517-zinnat-po-primeneniyu-analogi-tabletki-granuly-suspenziya-antibiotik-angina.html

Zinnat for children: instructions for use

Antibiotics of the cephalosporin group are considered very effective and are often prescribed to children for infectious diseases. One of the most popular among them can be called Zinnat, because unlike many other drugs in this group, it is presented not by injections, but by forms that can be taken orally. When it is prescribed to children, which form is preferable at an early age and how to dose such a medicine?

Release form

  • In bottles containing 1.25 g of white granules. They are distinguished by their size less than 3 mm and irregular shape. If you add water to them, you get a light yellow or white suspension with a fruity smell. A glass is included with the bottle so that you can accurately measure the amount of water to prepare the suspension, as well as a spoon for dosing the finished medicine.
  • In tablets that have a film shell. They are white in color and oval in shape, convex on both sides. The tablets are available in two dosages and are sold packaged in blisters of 10 pieces, one blister per pack.

Zinnat does not have other forms, such as syrup, capsules, sachets with powder or ampoules.

Compound

The active substance in any form of the drug is cefuroxime, represented by the compound “cefuroxime axetil”. In 5 ml of suspension it contains 125 mg, and in one tablet it can be either 125 mg or 250 mg.

Additional substances in the liquid medicine are xanthan gum, povidone K30 and stearic acid. The sweet taste of the drug is provided by aspartame, sucrose and acesulfame potassium, and the smell is provided by tutti-frutti flavoring.

Inside the tablets, cefuroxime is combined with sodium lauryl sulfate, hydrogenated vegetable oil, MCC, colloidal silicon dioxide and croscarmellose sodium. The drug shell is made from propyl and methyl parahydroxybenzoate, propylene glycol, hypromellose and white dye.

Operating principle

Zinnat is an antibiotic of the cephalosporin group and represents their second generation. It is active against a wide range of microorganisms, including beta-lactamase-producing bacteria, so this drug is effective if the microbes are not affected by amoxicillin or ampicillin. By influencing the formation of bacterial cell walls, cefuroxime has a bactericidal effect.

And now Dr. Komarovsky will tell us in which cases antibiotics are dangerous for children, and in which cases they are simply necessary.

The drug is active against Escherichia coli, Klebsiella, gonococci, Haemophilus influenzae, Proteus, various types of staphylococci, many types of streptococci, gram-positive and gram-negative bacilli, borrelia and many other microorganisms. However, Zinnat will not help if the cause of the infection is Listeria, Enterococcus, Enterobacter, Pseudomonas, Citrobacter, Legionella and some other bacteria.

In addition, staphylococci, Proteus, clostridia and other microbes that cefuroxime usually acts on may be resistant to the drug. For this reason, before treatment, it is recommended to determine the sensitivity of the pathogen. We should not forget that the medicine will not act on viruses, therefore Zinnat is not used for influenza, mononucleosis, chickenpox and other viral infections.

Indications

The drug is prescribed for infectious diseases caused by microorganisms sensitive to Zinnat. The reason for giving your child this medicine may be:

  • Otitis media, pharyngitis, sinusitis, tonsillitis or other upper respiratory tract disease.
  • Urethritis, pyelonephritis or cystitis.
  • Furunculosis, pyoderma or other bacterial skin infection.
  • Pneumonia or bacterial bronchitis.
  • Gonorrhea.
  • Borreliosis.

At what age is it allowed to take it?

The suspension is used in childhood in babies over 3 months. The neonatal period is a contraindication to this drug. Children from 3 months to 3 years are prescribed only the liquid form, and tablets are prescribed for those aged 3 years and older, provided that the child can swallow them without biting. If the child is over three years old (for example, 6 years old), but he protests against the solid form, a suspension is used for treatment.

Contraindications

Any form of medication is not used in the treatment of children intolerant to cephalosporins. Phenylketonuria is also a limitation for prescribing the suspension, since the composition of such Zinnat includes aspartame. If a child has renal pathologies or gastrointestinal diseases, the medication should be prescribed with caution. The presence of sucrose in the liquid form should be taken into account when used in patients with diabetes mellitus.

Antibiotics are irreplaceable in some cases, but there is another side to the coin, which Dr. Komarovsky will tell us about.

Side effects

Due to the use of Zinnat, the following negative effects are possible in a small patient:

  • Allergy. Most often, this reaction manifests itself as a skin rash, but may include hives, itching, or in rare cases, fever.
  • Loose stools, nausea or abdominal pain. Occasionally, taking the medicine leads to vomiting or colitis.
  • Dizziness.
  • Increased activity of liver enzymes. Sometimes the medicine provokes hepatitis or cholestatic jaundice.
  • Headache.
  • An increase in the number of eosinophils, a decrease in the number of platelets and leukocytes.
  • Candidiasis infection.

Instructions for use

Suspension

To dilute the granules, use a measuring cup, filling it with non-hot boiled water (37 ml) up to the mark. After shaking the granules, water is poured into them, the bottle is closed and turned over. The bottle should be shaken vigorously for about 15 seconds, then inverted and shaken a little more.

This medication can be given undiluted, measuring the required volume of the drug with a dosage spoon or a plastic syringe from the packaging of some other medicine (for example, Nurofen). If the child does not like the taste, the drug can be mixed with fruit juice or a small amount of milk before use. However, do not add any hot liquid to the suspension.

The drug is prescribed twice after meals. The dose for children over 2 years of age is usually 5 ml - from this volume of suspension the child receives 125 mg of cefuroxime per dose and 250 mg per day. If the baby has otitis media or some serious infection, the single dosage is increased to 250 mg (2 tablespoons of suspension), that is, the small patient receives 500 mg of cefuroxime per day.

For children under 2 years of age, the dose is often calculated by weight. This definition of a single dose of medication is often used for children over 2 years of age. To calculate, the child’s body weight in kilograms is multiplied by 10 (for severe infection - by 15). The resulting number is the amount of cefuroxime in milligrams that is given per dose.

Pills

This form of Zinnat is given after meals twice a day. The duration of treatment is determined by the doctor and can be 5-10 days, but most often the tablets are prescribed for 1 week.

In most cases, a single dose for a child is one tablet containing 125 mg of cefuroxime. In case of severe infection, either two tablets of 125 mg or 1 tablet with a dosage of 250 mg are given at one time.

The drug should be swallowed and washed down with a small amount of water.

The tablet should not break, grind into powder or break into several pieces. If the child cannot swallow it, it is better to abandon this form and prefer a suspension.

Overdose

If you drink a suspension in a dose greater than what the doctor prescribed, or take several tablets at once, this can cause nervous agitation, and some children experience convulsions during an overdose. Such negative symptoms are often treated symptomatically, and in severe cases, dialysis is performed.

Interaction with other drugs

  • It is not recommended to give Zinnat together with drugs that reduce the acidity of gastric juices, as this affects the absorption of cefuroxime and its bioavailability.
  • Combination with loop diuretics prevents the excretion of cefuroxime by the kidneys, causing its plasma concentration to increase.
  • If the tablets or suspension are given concomitantly with aminoglycoside treatment, it will cause kidney toxicity.

Terms of sale

To purchase Zinnat granules or tablets in pharmacies, you must show a prescription from a doctor. On average, one bottle of granules costs about 260 rubles, and the price of a package of 125 mg cefuroxime tablets is approximately 240 rubles.

Storage conditions

The package of tablets and the packaged bottle of granules should be stored at home in a place protected from children at temperatures up to +300C. The storage temperature of the finished suspension is +2+80C, therefore, after dilution with water, the drug is kept in the refrigerator. The shelf life of granules is 2 years, tablets - 3 years, suspensions after dilution - 10 days.

Reviews

In most cases, parents respond well to the treatment of children with Zinnat drugs. They confirm that such a medication very effectively fights otitis media, sore throat, sinusitis, boils, cough due to bronchitis and other problems caused by harmful bacteria. This is also confirmed by pediatricians, including the famous doctor Komarovsky.

Most often, a suspension is chosen for treating children, which is praised for its ease of dosing. Many mothers cite side effects as a disadvantage of the drug. It is most often noted that after taking Zinnat, diarrhea or vomiting occurs. In addition, some children do not like this medication.

Analogs

Zinnat can be replaced by other cefuroxime-based drugs, for example, the drugs Axetin, Zinacef, Cefurus or Cefurabol. However, almost all such drugs are presented as powder for injection. Only Axosef, Zinoximor and Cetyl Lupine are produced in tablet form.

Other antibiotics from the group of penicillins or cephalosporins, for example, Suprax, Ospamox, Ecoclave or Augmentin, can also replace Zinnat. Also, based on an analysis of the sensitivity of bacteria, the doctor can change Zinnat to antibacterial drugs such as Sumamed, Macropen, Vilprafen and other drugs. However, giving them to a child on your own is unacceptable. Only a specialist should determine which antibiotic is best for a particular infection.

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Source: http://www.o-krohe.ru/antibiotiki/zinnat/

Zinnat how to take

Antibiotic Zinnat for children: dosage, indications and precautions for use

The antibiotic Zinnat for children belongs to the group of cephalosporin antimicrobial drugs; its main active ingredient is cefuroxime. This medicine is prescribed very often for the treatment of many diseases, due to its wide spectrum of action.

All antibiotics of the cephalosporin group are conventionally divided into four generations, with each subsequent “working” against a larger number of pathogenic bacterial microflora. Antibiotic Zinnat for children belongs to the second generation.

It is effective against the following microflora:

  1. Gram-positive cocci, which are the main cause of sore throats, pneumonia and other pathologies of the respiratory system (Staphylococcus aureus, beta-hemolytic and pneumococcal streptococci Streptococcus pyogenes and S.pneumoniae).
  2. Gram-negative cocci:
    • Neisseria gonorrhoeae (gonococcus), the causative agent of gonorrhea.
    • Neisseria meningitis or meningococcus. In most cases, this bacterium parasitizes in the nasopharynx, causing frequent nasopharyngitis, but it also becomes a source of meningitis. However, Zinnat and other second-generation cephalosporins are not used to treat this disease, since they practically do not penetrate the blood-brain barrier into the brain.
    • Moraxella catarrhalis, which causes tonsillitis, sinusitis and otitis.
  3. Gram-negative bacilli: coliform, hemophilus (Escherichia coli, Haemophilus influenzae), salmonella (Salmonella enteridis, S. typhi), Shigella dysenteriae, some types of Proteus. This microflora causes infectious intestinal diseases.
  4. Gram-positive rods (Clostridium botulinum and C.tetani).

The antibiotic for children Zinnat has a bactericidal effect; it inhibits the activity of the enzyme transpeptidase, which takes part in the formation of the bacterial cell wall. Most cephalosporins are destroyed under the influence of the environment and microflora of the digestive tract, so they are administered by injection.

However, the active component of Zinnat is included in the form of the compound cefuroxime axetil, which allows you to take the medicine in the form of tablets or suspension. Biavailability after enteral administration is about 50%.

After enzymatic reactions in the intestine, it binds to blood plasma proteins in the form of cefuroxime, which provides a rapid therapeutic effect. Zinnat is excreted through the kidneys in unchanged form approximately 8 to 12 hours after use. This is also related to the dosage regimen of the antibiotic - it must be taken twice a day at approximately the same time.

The reasons for prescribing the antibiotic Zinnat for children and older people are the following diseases:

  • Infectious pathologies of the respiratory system: inflammation and abscesses of the lungs, complications after surgical interventions.
  • Diseases of the ENT organs: otitis, sinusitis, tonsillitis, pharyngitis, sinusitis, sore throat.
  • Infections of the genitourinary system: pyelonephritis, bacterial damage to the bladder and urethra, gonorrhea, cervicitis, bacteriuria of unknown etiology, prostatitis.
  • Bacterial processes on the skin: pyoderma, pustular rash, furunculosis.
  • Systemic infections: sepsis, peritonitis, tick-borne borreliosis in the early stages.

The manufacturer of the drug Zinnat is the British company GlaxoSmithKline. The medicine is available in the form of tablets of 250 mg and 125 mg and granules for making a suspension (at the rate of 125 mg of the active ingredient per 5 ml).

In addition to the bottle of powder, there is a 5 ml measuring spoon and a cup.

As for side effects, parenteral administration of cephalosporins very often leads to an allergic reaction.

However, when using the antibiotic Zinnat, a similar risk is present.

Namely, with increased sensitivity to the compounds included in the medication.

Contraindications to its use are:

  • Diseases of the digestive system, especially if they are accompanied by bleeding.
  • Pregnancy. Although clinical trials have not been conducted regarding the effect of Zinnat on the fetus, doctors avoid using the drug in the first trimester during the formation of the child’s internal organs and systems.
  • Lactation.
  • Age up to 3 months.

Side effects of the antibiotic Zinnat for children manifest themselves as:

  • Dyspeptic symptoms: heartburn, nausea, vomiting, stool disorders.
  • Changes in blood tests: decrease in the number of leukocytes (leukopenia), platelets (thrombocytopenia), erythrocytes (anemia), eosinophils (eosinophilia).
  • Central nervous system reactions: headache, dizziness, very rarely - seizures.
  • Allergic manifestations: itching, rashes like urticaria.

A doctor must prescribe the drug and calculate the dosage. Self-medication is fraught with the development of bacterial resistance to the active component of the drug. The antibiotic Zinnat for children under 3 years of age is prescribed only in the form of a suspension.

It must be done as follows:

  1. Prepare 20 ml of boiled water cooled to room temperature.
  2. Shake the bottle of granules.
  3. Pour the water into the bottle, turn it upside down and shake vigorously to evenly distribute the powder (at least 15 seconds).

The antibiotic Zinnat for children is not available in the form of syrup, since the granules of the active component do not dissolve in water. The taste of the suspension is pleasant and sweet, which is of no small importance in pediatric practice. In most cases, the dosage of the drug is calculated using the formula 20 mg of cefuroxime per 1 kg of child weight.

The age correspondence to the amount of medicine is given in the table:

For severe bacterial infections of the lower respiratory tract and otitis media, the pediatrician prescribes a large dose of the antibiotic Zinnat for children - 30 mg/kg. The drug should be taken as follows:

For children who can swallow the capsule themselves, the medicine is prescribed in tablet form. Depending on the severity of the disease, you should take 125 mg or 250 mg twice a day.

For adults, the dosage of Zinnat is higher:

  • For the treatment of uncomplicated respiratory tract infection and pyelonephritis: 250 mg twice daily.
  • For the treatment of diseases of the lower urinary system: 125 mg twice a day.
  • For the treatment of gonorrhea: 1 g once (4 capsules of 250 mg each).
  • For the treatment of severe otitis and pathologies of the respiratory system: 500 mg twice a day.

Antibiotic Zinnat for children and adults should be taken during meals with a small amount of water. The duration of therapy is determined by the doctor, on average it ranges from 5 to 10 days.

When treating pneumonia in a hospital setting, the principle of stepwise therapy is used.

During the first three days, cefuroxime in the form of injections (Zinacef) is prescribed at a dosage of 1.5 g twice a day. Then Zinnat (500 mg twice a day) is prescribed for a week. To relieve exacerbation of chronic bronchitis, injections of Zinacef (750 mg twice a day) are also given for three days, and then Zinnat is prescribed for 7 days in a dose of pomg capsules twice a day.

According to doctors, when parents find out that the drug is a second-generation cephalosporin, they ask to prescribe a stronger drug. However, if the disease is caused by antibiotic-sensitive bacteria, this does not make sense.

Medicines of the third and fourth generations have a serious effect on the body. Zinnat is generally safe; side effects from its use are rare and reversible.

Several drugs are registered in Russia, the main active ingredient of which is cefuroxime.

Comparative descriptions and prices of analogues are given in the table:

Granules for the preparation of suspension 125 mg/5 ml.

260 - 280 rubles. 420 - 450 rubles.

300 - 330 rubles.

The antibiotic Zinnat for children and adults has one advantage over other analogues - the release form. This allows treatment to be carried out at home (but always under the supervision of a pediatrician), without psychologically traumatizing the child with injections.

Doctors note the effectiveness of the drug, the rapid onset of results, and good tolerability. Patients talk about the relatively low price of the antibiotic combined with the excellent quality of the drug. Negative reviews and lack of proper therapeutic effect are associated with non-compliance with the instructions and timing of treatment.

Zinnat antibiotic for children: indications and instructions for use

Modern medicine cannot be imagined without antibiotics. Often, without their help, it is impossible to cope with a bacterial infection, but we must not forget that the use of these potent drugs requires proper control. Find out detailed information about Zinnat antibiotic, what mechanism of action it has and what diseases it will help cure. In the article you will find information about the peculiarities of using this drug in adults and children, what side effects the drug has, and when its use is contraindicated.

Pharmacology of the action of the antibiotic Zinnat

This drug is a second generation cephalosporin and belongs to the pharmacological group of antibacterial agents for systemic use. The active ingredient of the drug is cefuroxime, which is in the form of cefuroxime axetil in the drug. This antibiotic has a bactericidal effect in the following way. Cefuroxime binds to the main proteins from which bacterial cell walls are synthesized and stops such cellular synthesis. This stops the reproduction mechanism of bacteria, they die, and the body recovers.

Zinnat is an effective antibiotic for infectious and inflammatory diseases if they are caused by microorganisms sensitive to the action of the drug. To predict the effectiveness of use in a particular case, a drug sensitivity test is performed. Based on the results of such a test, the doctor will assess the advisability of prescribing the drug, and the patient will be confident that he will be justified in taking this potent medicine.

Indications for taking the antibiotic Zinnat are:

  • infection of the upper and lower respiratory organs (pharyngitis, sinusitis, bronchitis, pneumonia);
  • infections of soft tissues and skin (pyoderma, furunculosis);
  • urinary tract infection (urethritis, cystitis, pyelonephritis);
  • gonorrhea;
  • early stage treatment of Lyme disease and prevention of the late stage of this disease.

A suspension of this antibacterial agent is used even in infants from 3 months of age, and Zinnat in tablet form can only be used for children over 3 years of age. The finished suspension is not sold in pharmacies; it is diluted from granules specially produced for this purpose. It’s easy to prepare; to do this, you need to add 37 ml of boiled water at room temperature to a bottle of granules (there is such a mark on the included measuring spoon) and shake the contents vigorously for seconds.

Next, the suspension is used by measuring out the required amount and diluting it a little more with milk or juice. The duration of treatment and dosage of the antibiotic in this form of release is determined by the doctor; the course can be 5-10 days, 2 doses per day. It is better to take the medicine immediately after a meal, so it is better absorbed from the gastrointestinal tract. Read the instructions on what dosage to give Zinnat suspension to children of different ages:

Approximate body weight

Single dose, mg

Number of measuring spoons (5 ml) per dose

6 months – 2 years

12 – more than 20 kg

Cephalosporin antibiotic Zinnat in the treatment of bacterial infections in adults

For such patients, this drug is prescribed in the form of tablets or suspension in accordance with the dosage for optimal treatment of the identified disease. The duration of treatment is determined by the attending physician; often this period is 7 days, but can last from 5 to 10 days. The following dosage of Zinnat is established depending on the identified disease:

Single dose, mg

Method of administration, once a day

Mild to moderate lower respiratory tract infection

Severe infection of the lower respiratory tract, if pneumonia is suspected

Urinary tract infections

20 days 2 times a day

Features of taking the medicine Zinnat and its analogues

In cases where parenteral use of cefuroxime (not through the gastrointestinal tract) is indicated for more effective treatment, the drug Zinacef is prescribed. After relief of symptoms, oral administration of the antibacterial agent in the form of tablets or Zinnat suspension is continued. For example, antibiotics are used in this combined method for bronchitis at the stage of exacerbation of the chronic course of the disease, or for pneumonia. Tablets should not be broken or bitten when taken. During treatment with the drug and its analogues, it is necessary to monitor kidney function.

Find out how to choose antibiotics for pneumonia.

Side effects of the antibiotic

Zinnat is a potent antibiotic with a wide range of action; its task is to destroy pathogenic bacteria. But in the process of such a fight against infection, it often damages healthy microflora, which leads to an imbalance in the functioning of some body systems. The medicine may cause the following side effects:

  • individual allergic reactions of the body;
  • skin rash, urticaria;
  • dizziness and headache;
  • Gastrointestinal disorders - abdominal pain, nausea, diarrhea;
  • superinfection with fungi of the genus Candida;
  • disruption of the liver and bile ducts, etc.

During pregnancy

If necessary, the doctor may prescribe Zinnat during pregnancy if the expected risk to the child’s development is significantly less than the benefit that the expectant mother’s body will receive. Although the effect of cefuroxime on fetal damage in the first trimester of pregnancy has not been directly proven, this drug is prescribed with particular caution in the early stages of pregnancy. The active ingredient of the drug has the property of penetrating into breast milk, which must be taken into account when using it in nursing women.

When is Zinnat contraindicated for children and adults?

This medicine is not prescribed to people with hypersensitivity to cephalosporin antibiotics. With caution and under constant supervision of specialists, this antibiotic is prescribed to people with impaired kidney function, who have ever had gastrointestinal diseases, and pregnant and lactating women. It is forbidden for babies under 3 months of age and patients with phenylketonuria to take this medicine in the form of a suspension. Tablets are not prescribed to children under 3 years of age.

Video: Doctor Komarovsky: which antibiotics to choose for bronchitis

Reviews

My opinion is this: there is no more effective medicine for bronchitis than Zinnat. For me, colds and coughs are a common occurrence, and three months ago an acute respiratory infection was complicated by bronchitis. I had to take antibiotics because the cough was terrible. The antibiotic tablets worked quickly - after 2 days. I took the medicine for 5 days, as prescribed by the doctor.

Svetlana, 28 years old

I was looking for effective antibiotics for children with sore throat - my son often has a sore throat. The last time, even though they immediately started using the spray when the throat was red, the disease developed rapidly. The doctor prescribed Zinnat children's suspension. The medicine helped my son quickly, the fever began to subside on the second day. I was pleased that there were no side effects.

Although Zinnat helped my daughter cure bronchitis, she had to suffer with indigestion! I don’t know, maybe the prescribed probiotic did not suit her, but after the treatment the child was forced to follow a diet for a couple of weeks. We had difficulty coping with stomach pain. I don't think I will use this drug anymore.

ZINNAT

Cefuroxime axetil is a precursor to cefuroxime, which is a second generation cephalosporin antibiotic. Cefuroxime is active against a wide range of pathogens, including strains that produce β-lactamases. Cefuroxime is resistant to bacterial β-lactamases and is therefore effective against ampicillin-resistant or amoxicillin-resistant strains.

The bactericidal effect of cefuroxime is associated with the suppression of bacterial cell wall synthesis as a result of binding to the main target proteins.

In vitro, cefuroxime is active against the following microorganisms: gram-negative aerobes - Haemophilus influenzae (including ampicillin-resistant strains), Haemophilus parainfluenzae, Moraxella catarrhalis, Neisseria gonorrhoeae (including strains that produce and do not produce penicillinase), Escherichia coli, Klebsiella spp., Proteus mirabilis , Providencia spp., Providencia rettgeri; gram-positive aerobes - Staphylococcus aureus (including penicillinase-producing strains, but excluding methicillin-resistant strains), Staphylococcus epidermidis (including penicillinase-producing strains, but excluding methicillin-resistant strains), Streptococcus pyogenes and other beta-hemolytic streptococci, Streptococcus pneumoniae, Streptococcus group B (Streptococcus agalactiae); anaerobes - gram-positive and gram-negative cocci (including Peptococcus spp. and Peptostreptococcus spp.), gram-positive rods (including Clostridium spp., except Clostridium difficile, Propionibacterium spp.), gram-negative rods (including Bacteroides spp. and Fusobacterium spp.), gram-negative spirochetes ( Borrelia burgdorferi).

The following microorganisms are not sensitive to cefuroxime: Clostridium difficile, Pseudomonas spp., Campylobacter spp., Acinetobacter calcoaceticus, Listeria monocytogenes, methicillin-resistant strains of Staphylococcus aureus and Staphylococcus epidermidis, Legionella spp., Enterococcus faecalis, Morganella morganii, Proteus vulgaris, Enterobacter spp. , Citrobacter spp., Serratia spp., Bacteroides fragilis.

Review: Zinnat suspension for children for infectious and inflammatory diseases

When a child begins an inflammatory process in the body, most pediatricians prescribe antibiotics to relieve the disease. Parents treat such prescriptions with caution, because such drugs “kill” the intestinal microflora. Often, while taking antibacterial agents, children experience diarrhea, indigestion and other digestive problems. Zinnat suspension for children is usually well tolerated, without side effects.

The antibiotic Zinnat is effective only against bacterial infections.

Release form

The drug is produced in the form of a dry granular mixture, which must be diluted with water before use. It is due to this form that the medicine is stored for a long time. The granules for preparing the suspension are white or almost white in color and irregular in shape.

Zinnat for children contains 125 mg of the active substance (cefuroxime) in 5 ml of a ready-made diluted suspension. This is the children's dosage.

If for some reason the child refuses to take the drug in the form of a ready-made solution, then you can replace it with similar tablets. Their packaging should also say “125 mg”.

However, the tablets are prescribed for use only by children over three years of age. It is not recommended to grind them into powder, dilute or grind them. It is difficult for small children to swallow a fairly large and bitter tablet. That is why pediatricians prescribe a suspension to children.

Tablets are not prescribed for children under three years of age.

The official manufacturer of Zinnat suspension is GLAXO OPERATIONS UK, Limited (Great Britain). The company has its own representative office in the Russian Federation, located in Moscow. You can go there with any questions you may have.

Compound

The antibiotic contains:

  • cefuroxime axetil - 150 mg;
  • sucrose - 3.062 g;
  • stearic acid - 852 mg;
  • “tutti-frutti” flavoring – 100 mg;
  • acesulfame potassium - 21 mg;
  • aspartame - 21 mg;
  • povidone K30 - 13 mg;
  • xanthan gum - 1 mg.

In combination, all these substances are completely harmless to the child. Acesulfame potassium and aspartame are sweeteners; flavoring gives the medicine a sweet and pleasant smell. Povidone K30 is a harmless binder in Zinnat granules, which, when interacting with water, gives the medicine a homogeneous mass.

Indications for use

Antibiotic Zinnat is used during inflammatory and infectious diseases:

Since children of kindergarten age (2-6 years) most often suffer from ENT diseases (otitis, pharyngitis, sinusitis and others), the use of an antibiotic is completely justified: Zinnat copes with infections quickly and effectively.

Zinnat effectively copes with inflammation of the throat, nose, ear, acute and chronic bronchitis, and pneumonia.

Reviews from young mothers

Marina, child - 3 years old:

“When my son was diagnosed with bronchitis with obstruction, I was very scared. The doctor prescribed the antibiotic Zinnat. Taken strictly as directed, for 7 days. But already on the first day I noticed that my son’s temperature dropped from 39 to 37 degrees. And the cough changed from dry and barking to softer, with sputum discharge. The child was able to sleep normally at night!”

Alena, child - 5 years old:

“My daughter got severe otitis in kindergarten - she couldn’t sleep, eat, lie down, or play. The temperature is high - 40. They called a doctor to the house and immediately prescribed antibiotics - Zinnat suspension. The temperature dropped to 37.3°C after the first dose. And after the second, my daughter was able to eat without clutching her ear and screaming throughout the house. Five days later there was no trace of the infection left.”

How to prepare medicine

To prepare a suspension from granules, they need to be diluted with water. The dark glass bottle comes with a measuring spoon and a cup. The latter is designed for 37 ml of liquid. This is the amount of water required to dilute the mixture.

The bottle cap is equipped with special protection. Therefore, to open it, you first need to press on it with your thumb or palm, and only then unscrew it. After removing the protective film from the neck of the bottle, pour 37 ml of warm boiled water into it. To ensure a lump-free and homogeneous suspension, shake the bottle thoroughly. The manufacturer in the instructions (download instructions for use of the drug) indicates that 2-3 minutes is enough, but practice has shown that sometimes a little longer.

The medicine should be stored in the refrigerator for no more than 10 days after dilution.

To accurately remember the date of preparation of the suspension, you can write it down with a pen on the bottle. On average, an antibiotic is enough for a full ten-day course, which explains such a shelf life.

How to give Zinnat suspension

A measuring spoon designed for 2.5 ml is not always convenient to give the drug to small children, so it can be replaced with a special syringe for the children's antipyretic Nurofen or Ibufen with an accurate scale.

Because of the cloyingly sweet and at the same time nauseating taste, children are very reluctant to take the medicine voluntarily.

The syringe allows you not only to quickly administer the antibiotic, but also to more accurately measure the required dosage. You need to take the medicine with food. Review from Svetlana, child - 4 years old:

“The first time my son drank medicine from a spoon quickly, but it was small - 2.5 ml. And you need to give 5 mg at a time, as prescribed by the doctor. It was impossible to force him to drink a second helping. A measuring syringe from Nurofen helped: I measured it, opened the child’s mouth and poured it in. He swallowed and only winced slightly. The second time he asked for it from a syringe. And they threw away the measuring spoon.”

The suspension has an extremely unpleasant taste, so the easiest way to give the drug to children in the first year of life is from a syringe.

It is possible to add the suspension to juice or tea, but, as the practice of many parents shows, the child is reluctant to drink such a “cocktail”, preferring to quickly take pure medicine in a spoon or syringe rather than “stretch out” its use in a drink. To make it easier to take the antibiotic, you can drink it with either plenty of water or Fitolon syrup, for example. It helps to normalize the intestinal microflora and prevent dysbacteriosis, since it is completely natural in composition (based on pine and spruce needles, free of allergens, oregano and mint).

Dosage

In general, the dosage is prescribed by a pediatrician, but there are general rules. The amount of the drug is calculated based on the child’s body weight.

The dose is selected not only based on the child’s weight, but also taking into account the degree of neglect and severity of the disease.

The average course of treatment is 5-7 days. In some cases, its duration can be changed as prescribed by the treating pediatrician, whose instructions must be strictly followed.

How not to harm a child

After treatment with antibiotics, which have a detrimental effect on all, including healthy, bacteria in a child’s body, a course of recovery is usually required. To make it faster, while taking Zinnat, doctors additionally prescribe various drugs to normalize the intestinal microflora, for example, Linex or Lactobacterin. Taking them together with an antibiotic is not only possible, but also necessary, following the instructions of the attending physician.

Linex is a source of probiotic microorganisms; the medicine should be taken simultaneously with antibiotics.

Instructions for restoring a child’s immunity after antibiotic treatment →

A bottle of Zinnat suspension costs an average of rubles. The cost in different pharmacies may vary depending on their pricing policy.

When purchasing, you need to pay attention not only to the expiration date and contents, but also to the bottle itself. The letters on it must be printed clearly, without smudging.

Due to the not very pleasant and cloying taste, some children experience side effects such as nausea and vomiting. Sometimes taking the medicine causes dizziness.

Taking an antibiotic should be made as convenient as possible for the child. Most often, vomiting does not appear because of the drug itself, but because of a “moral factor.” The child subconsciously prepares to take a tasteless medicine, which makes him feel sick.

Try diluting the medicine with juice or compote.

Contraindications include:

  • individual intolerance;
  • allergy to components;
  • phenylketonuria;
  • hypersensitivity to the components of the drug.

Analogs

Of course, Zinnat in suspension is not the only children's antibiotic. It has equally effective analogues. Here is a short list with prices:

However, if the doctor prescribed Zinnat suspension for your appointment, then you need to purchase it. In the future, if for some reason the medicine is not suitable for you, it can be replaced with a more suitable one after consultation with a pediatrician.

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Source: http://sdelayusama.ru/kak-prinimat/zinnat-kak-prinimat.html

Zinnat

Description current as of 05/27/2016

  • Latin name: Zinnat
  • ATX code: J01DC02
  • Active ingredient: Cefuroxime (Cefuroxime)
  • Manufacturer: Glaxo Operations UK Limited (Great Britain)

Compound

Zinnat 125 mg tablets contain the active component cefuroxime axetil (125 mg in terms of cefuroxime). Zinnat 250 mg tablets also contain the active component cefuroxime axetil (250 mg in terms of cefuroxime). In addition, the medicine contains additional components: MCC, croscarmellose sodium, sodium lauryl sulfate, colloidal silicon dioxide, hydrogenated vegetable oil.

The granules from which the Zinnat suspension is prepared contain cefuroxime axetil as an active substance, as well as additional ingredients: stearic acid, sucrose, aspartame, acesulfame potassium, povidone K30, xanthan gum, flavoring.

Release form

The antibiotic Zinnat is available in the form of tablets and granules, from which a suspension is prepared.

  • Tablets with a white or almost white film shell, oval, biconvex shape. On one side they are engraved “GXES5” (dose 125 mg), “GXES7” (dose 250 mg). When cut, the tablet is white or almost white. Contained in a blister of 5 or 10 pcs. in a cardboard box - 1 or 2 bl.
  • Granules are grains of irregular shape, different sizes, but not more than 3 mm. Color – white or almost white. After dilution, a white or light yellow suspension is formed, which has a fruity aroma. Contains granules in dark glass bottles, 125 mg/5 ml. The bottle is closed with a plastic cap equipped with a child-proof device. A measuring spoon is also included in the cardboard box.

pharmachologic effect

The substance cefuroxime axetil is a precursor of cefuroxime, belonging to the second generation of cephalosporin antibiotics. Shows activity against a wide range of pathogens, including strains that produce β-lactamases.

Cefuroxime is noted to be resistant to bacterial β-lactamases, so the substance is effective against ampicillin-resistant or amoxicillin-resistant strains. It has a bactericidal effect, which is associated with the process of suppressing the synthesis of bacterial cell walls due to binding to the main target proteins.

In vitro activity of cefuroxime was noted against a number of gram-negative aerobes, gram-negative aerobes, anaerobes (gram-positive and gram-negative cocci, gram-positive and gram-negative rods, gram-negative spirochetes).

The following microorganisms are insensitive to cefuroxime: Pseudomonas spp., Clostridium difficile, Acinetobacter calcoaceticus, Campylobacter spp., strains of Staphylococcus aureus and Staphylococcus epidermidis that are resistant to methicillin, Legionella spp., Listeria monocytogenes. Also insensitive to the active substance of the drug Zinnat are certain strains of the following genera: Morganella morganii, Enterococcus (Streptococcus) faecalis, Serratia spp., Citrobacter spp., Proteus vulgaris, Bacteroides fragilis, Enterobacter spp.

Pharmacokinetics and pharmacodynamics

After the medicine has been taken orally, the substance cefuroxime axetil is slowly absorbed from the digestive tract. The substance is rapidly hydrolyzed to release cefuroxime in the small intestinal mucosa and in the blood. Penetrates through the placenta, the blood-brain barrier, and enters breast milk. Optimal absorption of the drug occurs if it is taken immediately after a meal.

The highest concentration of the active substance after taking the tablets is observed after approximately 2.4 hours, provided that the medicine was taken after a meal.

The highest concentration after taking the suspension is observed approximately 2-3 hours later, provided the medication is taken after meals.

The connection with plasma proteins is approximately 33–50%.

Cefuroxime is not metabolized in the body.

The half-life is 1–1.5 hours. It is excreted by tubular secretion and glomerular filtration. During dialysis, serum concentrations of the substance decrease.

Indications for use

Zinnat tablets and suspension are indicated for use against a wide range of gram-positive and gram-negative bacteria. It is used to treat infectious and inflammatory diseases caused by bacteria that are sensitive to cefuroxime:

Contraindications

All dosage forms of the drug Zinnat are contraindicated in case of hypersensitivity to β-lactam antibiotics (if there is a history of sensitivity to cephalosporin antibiotics, carbapenems, penicillins).

Zinnat tablets should not be taken by children under 3 years of age.

A suspension prepared from granules is not prescribed to people who have hypersensitivity to aspartame or phenylketonuria. This form of antibiotic should also not be used to treat children under 3 months of age.

Caution: Zinnat is prescribed for diseases of the digestive system (including a history), ulcerative colitis, impaired renal function, as well as during pregnancy and breastfeeding.

Side effects

As a rule, negative reactions when treated with a drug containing the active substance cefuroxime axetil are not significant, they are reversible and short-lived. The following side effects may occur:

  • superinfection with fungi of the genus Candida;
  • lymphatic and hematopoietic systems: eosinophilia, thrombocytopenia, false-positive Coombs test, leukopenia, in very rare cases - hemolytic anemia;
  • immune system: manifestations of hypersensitivity reactions in the form of skin rash, urticaria, itching, in very rare cases - serum sickness, drug fever, anaphylaxis;
  • nervous system: headaches, dizziness;
  • digestive system: gastrointestinal dysfunction, which is manifested by diarrhea, nausea, abdominal pain, sometimes vomiting, in rare cases - pseudomembranous colitis;
  • biliary tract and liver: transient increase in the activity of liver enzymes, in rare cases - hepatitis, jaundice (mainly cholestatic);
  • skin, subcutaneous fat: in very rare cases - erythema multiforme, Stevens-Johnson syndrome.

Instructions for use of Zinnat (Method and dosage)

Antibiotic Zinnat should be used only as prescribed by a doctor.

Zinnat tablets, instructions for use

As a rule, the medicine in tablet form must be taken for 7 days, but the duration of the course can be from 5 to 10 days. It is recommended to take the tablets after meals.

Adult patients with most infectious diseases are prescribed 250 mg of Zinnat 2 times a day. When treating infectious diseases of the urinary tract, it is recommended to take 125 mg of the drug 2 times. per day. For infectious diseases of the lower respiratory tract of mild and moderate severity, 250 mg of Zinnat is prescribed 2 times a day; for severe diseases, the dose is increased to 500 mg 2 times a day. per day. For uncomplicated gonorrhea, a single dose of 1 g of the drug is indicated.

For the treatment of Lyme disease, 500 mg 2 times is prescribed. per day, the course of treatment lasts 20 days.

For most diseases, children over three years of age are prescribed 125 mg of Zinnat 2 times a day. per day. Highest daily dose mg. When treating otitis media or severe infectious diseases, the doctor may prescribe 250 mg 2 times a day. per day. Permissible dose per day mg

Suspension Zinnat, instructions for use

The suspension is used orally for children; it is recommended for children over 3 months of age.

In most cases, the doctor prescribes a dose of 125 mg 2 times. per day. Children after reaching the age of two when treating otitis media or severe infectious diseases are advised to take 250 mg twice a day, but not more than 500 mg per day.

If the drug is prescribed to infants, the dose is calculated taking into account the child’s age and body weight. As a rule, children from 3 months. Prescribe 10 mg of the drug per 1 kg of weight 2 times. per day. For severe infections, the dose can be increased to 15 mg per 1 kg of weight 2 times. per day, but the child should not take more than 500 mg of medication per day.

Overdose

In case of an overdose of the drug, increased excitability of the brain may develop, including seizures. In this case, symptomatic therapy is carried out, taking into account the fact that serum concentrations of cefuroxime decrease during peritoneal dialysis and hemodialysis.

Interaction

The bioavailability of cefuroxime may be reduced when taking medications that reduce gastric acidity. Such drugs neutralize the effect of increasing the absorption of the drug when taken after meals.

Zinnat can affect the state of the intestinal microflora, and this leads to a decrease in estrogen reabsorption. As a result, the effect of hormonal oral combined contraceptives is reduced.

Since a false negative result is possible due to the ferrocyanide test, it is advisable to use hexokinase or glucose oxidase methods to determine the level of glucose in the blood and plasma.

Taking Zinnat does not affect the quantitative determination of creatinine by the alkaline picrate method.

When used simultaneously with loop diuretics, tubular secretion and renal clearance decrease, the concentration of cefuroxime in plasma increases, as well as its half-life.

When taken simultaneously with diuretics and aminoglycosides, the likelihood of developing nephrotoxic effects increases.

Terms of sale

Zinnat is sold according to prescription.

Storage conditions

Tablets and granules are stored at a temperature of no more than 30°. The finished suspension must be stored in the refrigerator, the temperature should be 2-8°C. All forms of Zinnat should be kept away from children.

Best before date

Zinnat tablets can be stored for 3 years, granules for 2 years. The shelf life of the finished suspension is no more than 10 days.

special instructions

Caution should be exercised when prescribing an antibiotic to people who have a history of an allergic reaction to beta-lactam antibiotics.

It is important to monitor renal function during treatment. This should be done charmingly to those patients who are receiving high doses of medication.

During treatment, patients may experience a false-positive urine reaction to glucose.

With prolonged use of the antibiotic Zinnat, active growth of fungi of the genus Candida is possible. Also, with prolonged treatment, the growth of some other resistant microorganisms may occur. In this case, it is advisable to discontinue therapy.

Since pseudomembranous colitis can develop during treatment with broad-spectrum antibiotics, it is important to differentiate pseudomembranous colitis in people who have severe diarrhea during antibiotic treatment or after completing a course of therapy.

When treating borreliosis with Zinnat, a Jarisch-Herxheimer reaction may occur, which is associated with the bactericidal activity of the drug against the spirochete Borrelia burgdorferi. Patients should be informed about the possibility of developing such symptoms.

If no clinical effect was noted within 3 days after the start of treatment, you should continue taking the drug.

Do not crush or break Zinnat tablets. Therefore, this form of medication is not prescribed to young children, as well as to those patients who have difficulty swallowing.

People with diabetes should note that 5 ml of the finished Zinnat suspension contains 0.25 XE.

Since axetil may cause dizziness when taking cefuroxime, patients should be warned about the need to drive carefully and engage in potentially hazardous activities.

Zinnat's analogs

Zinnat for children

Those reviews about Zinnat for children that parents leave indicate that this antibiotic is used frequently and successfully for children. Basically, children are prescribed a suspension, the intake of which effectively alleviates the child’s condition. It is important that the instructions for the suspension for children are strictly followed. It should be taken into account that tablets are not prescribed to children under 3 years of age, and the suspension is not prescribed to children under 3 months.

During pregnancy and lactation

The use of an antibiotic during pregnancy is possible only if the benefit to the woman outweighs the potential risk to the child. Prescribe with caution in early pregnancy. Since the active substance passes into breast milk, during lactation the medication can only be taken as prescribed by a doctor and under his supervision.

Reviews about Zinnat

Those parents who gave the antibiotic Zinnat to their children wrote mostly positive reviews. They note that the drug significantly improved the condition of infectious diseases after just a few days of use. However, side effects are rare. As a rule, these are allergic reactions and headaches. However, most patients, both adults and those users who gave the drug to children, note that there is a need to take probiotics after a course of treatment with this medicine. The ease of use of the product in the form of a suspension is also mentioned.

Zinnat price, where to buy

Antibiotic in the form of 125 mg tablets costs an average of 250 rubles for 10 tablets. The price of Zinnat 250 mg tablets is from 440 rubles. for 10 tablets The price of Zinnat suspension is from 280 rubles.

  • Online pharmacies in Russia Russia
  • Online pharmacies in Ukraine Ukraine
  • Online pharmacies in Kazakhstan Kazakhstan

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BIOSPHERE

Education: Graduated from Rivne State Basic Medical College with a degree in Pharmacy. Graduated from Vinnitsa State Medical University named after. M.I. Pirogov and internship at his base.

Work experience: From 2003 to 2013 – worked as a pharmacist and manager of a pharmacy kiosk. She was awarded diplomas and decorations for many years of conscientious work. Articles on medical topics were published in local publications (newspapers) and on various Internet portals.

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Source: http://medside.ru/zinnat