Oka solution instructions for use

Why and how is OKI solution used to rinse the mouth and throat?

OKI solution for rinsing is prescribed exclusively for local use and is used for pain relief, treatment and prevention of inflammatory processes in the oral cavity and pharynx.

Table of contents:

The medication is also used to treat various ENT diseases, but in this case it must be taken in conjunction with other medications prescribed by the attending physician.

Composition of the drug

The drug OKI is a transparent green liquid with a mint aroma. Available in plastic bottles with a 150 ml dispenser. The kit includes instructions and a measuring cup that allows you to accurately dose the product during preparation.

The main component is ketoprofen lysine salt (dissolves quickly and does not have a harmful effect on the stomach), which provides the antipyretic, anti-inflammatory and analgesic effect of the drug. The auxiliary components are:

  • ethanol, glycerol and methyl parahydroxybenzoate (preservatives that increase the shelf life of the drug);
  • natural menthol flavoring;
  • sodium saccharinate (sweetener);
  • sodium dihydrogen phosphate (added as an emulsifier);
  • brilliant green (synthetic aniline dye);
  • water.

pharmachologic effect

The therapeutic effect of the drug consists of a direct effect on the inflammatory process or the focus of the disease.

The drug has analgesic, antipyretic and anti-inflammatory effects. It also exhibits an antibradykinin effect, helps delay the release and stabilize enzymes of lysosomal membranes, and reduces the activity of cytokines and neutrophils.

It is worth noting that this solution does not have an antibacterial effect on the oral cavity and throat.

Indications and contraindications

Quite often, OKI solution is used as an anesthetic when performing various dental procedures.

The main purpose of the drug is to relieve acute inflammatory processes and pain in the pharynx and oral cavity resulting from:

  • hypertrophic gingivitis (gum disease, characterized by bleeding and swelling);
  • erosive-ulcerative and herpetic stomatitis;
  • inflammatory processes in the tongue resulting from injuries or exposure to microorganisms (glossitis);
  • acute or chronic laryngitis (inflammation of the vocal cords);
  • diseases of the mucous membrane, as well as lymphoid tissue of the pharynx;
  • inflammation of the tonsils (angina);
  • ulcerative formations of various origins, for example, those that appeared as a result of wearing dentures or with the development of aphthous stomatitis;
  • chronic periodontal disease;
  • dental operations.

This medication is contraindicated for use in the following cases:

  • during pregnancy;
  • in childhood (up to 6 years);
  • during breastfeeding;
  • if you have problems with blood clotting;
  • hypersensitivity to the substance ketoprofen;
  • stomach ulcers.

Preparation of the solution, application and dosage regimen

To prepare a rinse solution, you need to boil 0.1 liters of water, and then add the OKI drug to it in the following amount:

  • for adults – 10 ml;
  • for children from 6 to 12 years old – 4 ml;
  • for children aged 12 years and older – 6 ml.

During the day, you need to rinse your throat and mouth twice with the resulting solution (preferably after eating and thoroughly brushing your teeth).

The course of therapy lasts on average 3–4 days. If during this time a positive effect is not observed, then you need to contact a specialist.

Features of application and special instructions

OKI solution is intended for local use only; according to the instructions, adults are prescribed the drug 2 rinses per day with 10 ml of solution (no more than five injections per dose).

Adolescents over 12 years of age: 1 rinse per day containing 3 sprays. Children from 6 to 12 years old - 1 rinse per day (2 sprays).

Reducing the dose of the drug is recommended for the treatment of:

  • elderly patients;
  • patients with functional disorders of the kidneys or liver;
  • patients suffering from bronchial asthma.

Accidental ingestion of the solution does not pose a potential danger to the patient, since the amount of the active substance in the solution does not exceed the dose recommended for oral administration.

Without a doctor's prescription, the medicine can be taken for no more than five days. During the treatment period, it is recommended to refrain from activities related to the need for concentration or a rapid psychomotor reaction.

The use of the drug by patients suffering from chronic liver diseases is indicated only under the close supervision of a specialist. Using the solution may mask signs of an infectious disease.

Side effects

The use of the drug in the form of a solution may cause the following side effects:

  • Gastrointestinal tract - indigestion, nausea, pain in the abdominal area;
  • respiratory system - laryngospasms, spasms or swelling of the larynx;
  • liver – increased bilirubin levels, increased activity of liver transaminases;
  • allergic reactions - itching, swelling of the oral mucosa and throat;
  • local manifestations – burning, itching, exacerbation of hemorrhoids.

No cases of overdose were observed. If any adverse reactions occur after taking the drug, you should immediately inform your doctor.

Opinion of doctors and patients

The point of view of practicing professionals and reviews of patients who used OKI solution for rinsing for therapeutic and preventive purposes.

I have been prescribing OCI solution to my patients for several years now. When properly prescribed and used, the medicine gives excellent results. After 2-3 days of use, cough, sore throat, sore throat, and swelling of the mucous membranes practically go away. In practice, I have not observed any cases of overdose; side effects are very rare. I think the only disadvantage of the drug is the cost, since not all patients can afford to take it.

Olga Ivanovna, therapist

I first learned about this solution when I became seriously ill with a sore throat. Due to severe inflammation of the throat, it was difficult to breathe, I could neither sleep nor eat. I gargled with a solution in parallel with taking antibiotics. I noticed a positive effect immediately. Within one day of taking it, the swelling went down and I began to feel much better. I didn't notice any side effects. Now this drug is always in our first aid kit.

After installing the dentures, I began to experience very severe irritation of my gums. The prosthesis squeezed and rubbed my jaw. The dentist advised me to rinse my mouth with OKI solution. I am very pleased with the result, since the drug relieved pain and irritation literally before our eyes.

What can be replaced?

This medicine has no 100% analogues in terms of its purpose and composition. Among the drugs with a similar active ingredient are Flamax, Artrum and Ketonal. However, all of them are intended for oral use or injection.

Analogues of the drug according to the pharmacological group and direction of action - Faspik and Advil. For the treatment of inflammatory processes in the oral cavity, OCI solution is often replaced by Kamistad and Halls Max.

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Source: http://dentazone.ru/preparaty-oborudovanie/medicamenty/rastvor-oki.html

OKI rinse solution: instructions for use, analogues

The drug OKI solution belongs to the NSAID group. It is an analgesic and anti-inflammatory agent. Manufacturer: DOMPE FARMACEUTICI. Production facilities are located in Italy.

The main active ingredient is ketoprofen in the form of lysine salt. It has an inhibitory effect on the metabolic enzymes of arachidonic acid, which is a precursor of prostaglandins. These substances play a leading role in the formation of pain, inflammatory response, and increased body temperature.

Maximum concentrations of the main active substance are observed in the blood 1–5 hours after taking the drug. Ketoprofen is excreted from the body through the urinary system.

Indications for use

The solution is used for local treatment of inflammatory diseases of the oral cavity and nasopharynx.

The drug is used in the following cases:

  • stomatitis;
  • gingivitis;
  • inflammatory processes in the tongue – glossitis;
  • mouth ulcers;
  • periodontal disease, including chronic form;
  • tonsillitis of various origins;
  • pharyngitis;
  • laryngitis;
  • as an anesthetic during dental procedures;
  • during preparatory activities during examination of the oral cavity.

Release forms

OKI solution is a green liquid for topical use with the aroma and taste of mint. Available in 150 ml plastic bottles with an injection dispenser or a 10 ml measuring cup.

Effective dosages

Effective dosages depend on the patient's age. To prepare the solution for treating the oral cavity, prepare a clean glass. Open the bottle with the drug and measure out 10 ml of liquid using a measuring cup. If a package with a dispenser is used, then apply 5 injections into the prepared container. Then add half a glass of water.

Effective dosages for different age groups:

  • children from 6 to 12 years old - 4 ml of OKI or 2 injections should be diluted for 1 rinse;
  • from 12 to 18 years – 1 rinse will require 6 ml of the drug or 3 injections;
  • from 18 years and older – 10 ml or 5 injections.

Treatment of the oral cavity is carried out 2 times a day with an interval of 12 hours.

Use during pregnancy

The drug is prohibited for use in the last third of pregnancy. In the first and second trimester, “OKI” is prescribed in cases where the potential benefit for the woman is greater than the threat to the fetus.

During breastfeeding, the use of ketoprofen is prohibited. If it is necessary to use the drug "OKI", stop feeding.

Contraindications and precautions

There are few contraindications to the use of the drug. OKI should not be prescribed in the following cases:

  • ulcer in the acute period;
  • erosive gastritis;
  • intolerance to ketoprofen and other NSAIDs;
  • aspirin intolerance;
  • nephropathy;
  • hepatopathy;
  • children under 6 years old;
  • pregnancy at 30–42 weeks of gestation.

Liver and kidney diseases are a relative contraindication. It is necessary to monitor the condition of the urinary system during treatment with ketaprofen.

Compatibility

The drug should not be used simultaneously with other drugs in this group. This enhances the negative effect of ketaprofen on the mucous membranes of the stomach and intestines.

The OKI solution is not used simultaneously with the following drugs:

  • diuretics – reduces the effectiveness of the latter, increases the risk of developing renal failure;
  • anticoagulants – increases the likelihood of bleeding;
  • lithium preparations – increases the concentration of lithium ions in tissues to toxic levels;
  • methotrexate – increases the side effects of the drug;
  • valfarin – bleeding up to death.

Side effects

Side effects of the OKI solution are both system-wide and local in nature.

Local reactions when using the solution are manifested by burning in the oral cavity, irritation, and the appearance of cracks in the corners of the mouth. Accidental ingestion of the solution will not cause additional harm, since the dosage corresponds to the maximum permissible dose of the drug.

Description of overdose

Currently, medical statistics do not reflect cases of drug overdose.

Conditions and shelf life

The period of use of the OKI solution for treating the oral cavity is 2 years from the date of issue. To purchase the drug you will need a doctor's prescription. There are no special storage requirements; it is enough to avoid open sunlight. Do not freeze.

Analogues of OKI solution

Drugs with a similar effect are widely available on pharmacy shelves, but there are no complete analogues of OCI solution prescribed in the complex treatment of diseases of the oral cavity.

Plisov Vladimir, doctor, medical observer

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The information is provided for informational purposes only. Do not self-medicate. At the first sign of disease, consult a doctor. There are contraindications, a doctor's consultation is required. The site may contain content prohibited for viewing by persons under 18 years of age.

Source: http://okeydoc.ru/oki-rastvor-dlya-poloskaniya-instrukciya-po-primeneniyu-analogi/

OKI - instructions for use, composition, release form, dosage, contraindications, analogues and price

Oki is intended to relieve swelling accompanying joint diseases - arthritis - the instructions for use of the medication contain information about other indications for use. Anti-inflammatory agent relieves fever, chills, can be used by adults and children. Read the instructions for use of the medicine to ensure that you take it correctly.

Oka's medicine

The generally accepted pharmacological classification classifies the Oki drug in question as a non-narcotic anti-inflammatory drug that has an analgesic and antipyretic effect. The medication relieves inflammation, reduces fever and relieves pain reactions due to the active ingredient – ​​lysine salt of ketoprofen.

Composition and release form

Oka is available in the form of rectal suppositories (for adults and children), granules for solution and solution for topical use. Detailed composition of each drug:

Concentration of ketoprofen lysine salt, mg

Additional components of the composition

Sodium chloride, mannitol, colloidal silicon dioxide, sodium saccharin, ammonium glycerate, mint flavor

Ethanol, glycerol, mint flavor, sodium saccharin, methyl hydroxybenzoate, menthol, brilliant green (verde certosa), water, sodium hydrogen phosphate

White or pale yellow, with a mint scent

White or light yellow, torpedo-shaped

Transparent solution, green in color, with mint aroma

12 or 20 sachets

150 ml bottles with 2 ml injection dispenser and plastic cap for reconstitution

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Pharmacodynamics and pharmacokinetics

The drug belongs to non-steroidal anti-inflammatory drugs (NSAIDs). The active substance of the drug is a derivative of propionic acid and has an analgesic, antipyretic and anti-inflammatory effect. The mechanism of action of the component is associated with inhibition of the activity of the main enzyme in the metabolism of arachidonic acid, which is considered a precursor of prostaglandins that cause inflammation, pain and fever.

Ketoprofen has an analgesic effect due to peripheral and central mechanisms of action. The first is associated with the suppression of prostaglandin synthesis, the second - with the inhibition of the same process in the central and peripheral nervous system, the effect on the biological activity of neurotropic substances. Ketoprofen has anti-bradykinin activity, stabilizes liposomal membranes, inhibits the activity of neutrophils in rheumatoid arthritis, and inhibits platelet aggregation.

When taken orally or rectally, ketoprofen is absorbed from the gastrointestinal tract, reaching maximum concentration after 1-5 hours when administered orally, after a minute when administered rectally, after a minute when administered intramuscularly and after five minutes when administered intravenously. The component binds to blood plasma proteins by 99% and penetrates the blood-brain barrier. The effect of the drug lasts for 2-18 hours, it penetrates into the synovial fluid, the remainder is excreted by the kidneys or intestines.

Indications for use

Oki - the instructions for use of the drug indicate the following indications for its use:

  • articular syndrome, inflammatory diseases;
  • rheumatoid arthritis, osteoarthritis, ankylosing spondylosis, polyarthritis;
  • gout, periarthritis;
  • arthrosynovitis, tendonitis, tenosynovitis;
  • bursitis, lumbago;
  • neuralgia, myalgia, pain after dental treatment, other dental procedures;
  • uncomplicated injuries, including sports injuries, sprains, sprains or ruptures of ligaments and tendons;
  • bruises, post-traumatic and post-operative pain;
  • otitis;
  • stomatitis, gingivitis, sore throat, laryngitis;
  • combination therapy of phlebitis, periphlebitis, lymphangitis, superficial lymphadenitis.

Directions for use and dosage

Inside each package of medicines there are instructions for use, which indicate the method of use and dosage. The solution can be applied topically, for gargling, or administered intravenously or intramuscularly. Suppositories are used for rectal administration, granules for preparing a solution - inside, orally.

Oka solution

In ENT practice and dentistry, Oka solution is used for the throat. According to the instructions, adults are prescribed two mouth rinses per day, each of which contains 10 ml of solution (five injections). For adolescents over 12 years of age, one mouth rinse requires 6 ml of solution (three injections). The solution is prepared in a glass that comes with the package. 100 ml of water is poured into it, the required amount of the drug is sprayed (one press corresponds to 2 ml). According to reviews, accidental ingestion of the solution does not lead to serious negative consequences.

For the treatment of acute conditions and relief of exacerbations in the process of chronic inflammation, the solution can be administered intravenously or intramuscularly, no more than 100 mg at a time. It is also allowed to use the drug externally - apply to affected surfaces twice a day. The course of treatment and dosage of the drug is prescribed by the attending physician.

Oka granules

Oka powder is intended for oral use. The dosage is determined individually. According to the instructions, adults are prescribed one full dose (the contents of a two-volume sachet is 80 mg). The granules are dissolved in half a glass of drinking water and taken three times a day with meals. For elderly patients, the dosage is halved. Children 6-14 years old should take half the dose of the 80 mg sachet (tear it along the line marked “half dose”). The maximum dose for adults is 300 mg/day, for children – 150.

Oka candles

The maximum dose for the use of rectal suppositories for adults is 480 mg/day. Patients over 18 years of age should use one suppository 2-3 times a day. Elderly patients should not use more than two rectal suppositories in one day. This is due to possible negative consequences for the body, an overdose of the active component.

Suppositories for children

According to the instructions, children should use suppositories with a ketoprofen concentration of 60 mg. Suppositories are administered rectally 1-2 times a day for a child 6-12 years old (with a body weight of more than 30 kg), or three times a day for children over 12 years old. The daily dosage for children is 5 mg/kg body weight. Doctors warn that suppositories should not be used for longer than five days, unless prescribed by a pediatrician.

special instructions

The instructions for use of the drug Oki indicate that it should be used with caution in patients with a history of liver, kidney, gastrointestinal diseases, dyspeptic symptoms, or immediately after major operations or implantations. During drug treatment, doctors must systematically monitor the patient's liver and kidney function. The drug affects the speed of psychomotor reactions, inhibiting concentration.

Okie during pregnancy

The drug Oki is contraindicated for use in the third trimester of pregnancy. According to the instructions, the use of the medication in the first and second trimesters is possible if the doctor evaluates the potential benefit to the mother versus the risk to the fetus. During breastfeeding, treatment with ketoprofen is prohibited due to the penetration of the active substance into breast milk.

In childhood

The instructions for use of the drug Oki warns that granules for preparing the solution and rectal suppositories are contraindicated for children under 12 years of age; the rinsing solution is prescribed only for those over 12 years of age. When using rectal suppositories, you should choose the option with ketoprofen concentrations of 30 or 60 mg; their packs may say “children’s.”

Drug interactions

When taking the drug Oki and other medications simultaneously, negative manifestations indicated in the instructions are possible:

  • other NSAIDs, thrombolytics, Heparin, Ticlopidine increase the risk of developing erosions, ulcers in the gastrointestinal tract, and bleeding;
  • Oki reduces the effectiveness of antihypertensive drugs, beta-blockers, diuretics, increases the hypoglycemic effect of insulin;
  • acetylsalicylic acid, probenecid reduce the effectiveness of ketoprofen;
  • when combined with lithium preparations, the concentration of lithium in the blood plasma increases to a toxic level;
  • diuretics lead to the development of renal failure;
  • increases the side effect of taking Methotrexate;
  • Warfarin causes severe, fatal gastrointestinal bleeding.

Side effects

The instructions for use of the drug Oki indicate the following possible actions when taking ketoprofen:

  • stomach pain, nausea, vomiting, constipation, diarrhea;
  • gastralgia, liver dysfunction, erosions, gastrointestinal ulcers, bleeding, perforation;
  • headache, tinnitus, drowsiness, dizziness;
  • peripheral edema, asthma attacks;
  • impaired renal function, skin rash, bronchospasm;
  • irritation of the rectal mucosa, pain during bowel movements, itching, burning.

Overdose

According to the information specified in the instructions for use, there have been no reports of cases of overdose with the drug Oka. Theoretically, the manifestations of an overdose can be similar to side effects, only amplified many times over. Treatment involves gastric lavage, sorbents and other therapy similar to NSAID poisoning.

Contraindications

Depending on the form of release of the drug Oki used, the contraindications for its use indicated in the instructions differ:

  • for oral administration: erosion, gastrointestinal ulcer in the acute phase, aspirin triad, impaired renal and liver function, third trimester of pregnancy, hypersensitivity to the components of the drug or salicylates, children under 12 years of age;
  • for rectal administration: proctitis, rectal bleeding;
  • for external use: weeping dermatosis, eczema, abrasions, wounds with infectious diseases;
  • general: peptic ulcer, hemophilia, Crohn's disease, diverticulitis, bronchial asthma, blood diseases.

Terms of sale and storage

Oka granules are dispensed from pharmacies with a prescription, all other forms of release are available without it. The drugs are stored at temperatures up to 25 degrees, away from children. The shelf life is two years for solution and granules, three years for suppositories with a concentration of 30 and 60 mg, five years for suppositories with a concentration of 120 mg.

Analogues of Oka

On the shelves of Russian pharmacies you can find direct and indirect analogues of Oka. The former are similar in composition, while the latter have a different active substance, but work the same way. Popular analogues produced by pharmacological enterprises:

Oka price

You can buy Oki through pharmacies or the Internet at a cost that depends on the chosen form of release and the concentration of the active ingredient. Approximate prices for Moscow and St. Petersburg:

Price when purchasing online, in rubles

Pharmacy price, in rubles

Sachets of granules 80 mg, 2 g, 12 pcs.

Rectal suppositories 120 mg, 10 pcs.

Solution, bottle 150 ml

Reviews

If I have a cold, I immediately go to the pharmacy and buy Oki for gargling in the form of a solution. I like that it instantly relieves pain and even brings down the onset of fever. The medicine also has a convenient format - it comes with a glass, so you don’t have to look for something to dilute it in. I gargle twice a day and forget about the disease.

The child sometimes develops an incomprehensible temperature and suffers from fever. The last time, to eliminate such symptoms, the doctor prescribed Oka rectal suppositories for us. They contain ketoprofen, which quickly relieves negative symptoms. I inserted suppositories once a day, at night, and after three days the child returned to normal life.

I play sports professionally, so injuries and bruises are not uncommon for me. If there is a nagging pain in the spine, I use Oka granules. To use them quickly and effectively - I dilute the contents of the sachet in water and drink. If the pain is not severe, it goes away immediately, otherwise it takes about a week to be treated. My review is positive!

I am showing the first signs of gout, my joints hurt, and my mobility is limited. During the examination, the doctor said that this can be prevented and the degree of pain can be reduced. I was prescribed Oka rectal suppositories, but I doubted how they could relieve pain. I’d rather take pills than use suppositories, they don’t inspire confidence in me.

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and make recommendations for treatment based on the individual characteristics of a particular patient.

Source: http://sovets.net/14745-oki-instrukciya-po-primeneniyu.html

"Oka" solution for gargling - instructions for use

It often happens that the throat is a little sore in the evening, but in the morning it hurts a lot and makes it impossible to even swallow saliva. In such a situation, Oki gargling solution can help.

If you don’t wait until your throat starts to hurt, but gargle it even when it starts to feel sore, you can prevent the disease. The fact is that viruses or bacteria, when they get on the mucous membranes, do not immediately make themselves felt. They need time to strengthen themselves and begin to act. Accordingly, by gargling, you can simply wash them off, thereby reducing the number of pathogenic microorganisms.

For purulent sore throat and an unpleasant white coating, rinsing with Oka is a very effective way to fight infection, inflammation and purulent formations.

Through this simple procedure, putrefactive tissues are destroyed and washed away from the surface of the mucous membranes of the mouth and throat, which significantly speeds up the healing process.

Composition of the Oka solution

"Oki" is a gargling solution based on the non-steroidal anti-inflammatory drug - ketoprofen. It is included in the drug as the lysine salt of ketoprofen. As a result of the interaction of the amino acid lysine and ketoprofen, a salt that is easily soluble in water is formed, which is used in the solution.

The product contains auxiliary elements: glycerol, ethanol, methyl parahydroxybenzoate, natural menthol flavor, sodium saccharinate and brilliant green. The first three substances act as preservatives so that the medicine is stored longer and does not lose its beneficial properties. Zelenka colors the drug in an unusual color.

At the pharmacy, the solution is sold in white opaque plastic bottles. The kit includes a dispenser, a measuring cup, a container with solution and instructions. The medicine is a liquid of a beautiful emerald color with a pronounced minty smell and taste.

Therapeutic effect

The drug acts locally, directly at the site of the disease. Gargling "Oka" provides an anti-inflammatory and analgesic effect. Quickly relieves inflammation, swelling, eliminates pain. Due to the fact that during the procedure a small amount of the main active substance ketoprofen enters the blood, it must be used several times a day.

Since Oki does not have an antibacterial effect, when pathogenic flora appears, appropriate medications should be additionally used. This solution slightly inhibits pathogenic bacteria and clears the throat of purulent discharge during a sore throat, thereby maintaining the positive effect of antibiotics.

Indications for use

Most often, Oki is used for rinsing when:

It is not recommended to use the solution if you have:

  • blood clotting is impaired;
  • stomach ulcer;
  • bronchial asthma;
  • late pregnancy;
  • lactation period;
  • intolerance to ketoprofen.

It is not advisable to use Oki for children under six years of age. Side effects manifest themselves in the form of an allergic rash and runny nose. Sometimes there is so-called “aspirin” asthma.

Gargling with Oka solution - instructions

  • Solution dosage

Pour 100 ml of clean drinking water into the plastic measuring cup included in the kit. Next, turn the dispenser on the bottle to the working position in the direction where the “Open” inscription appears and press it. 2 ml of product comes out at a time.

To treat adults, squeeze 10 ml of the product into a prepared glass of water using a dispenser, and for adolescents twelve years of age and older - 6 ml. For those who are already 6 years old, but not yet 12 - 4 ml. It is necessary to rinse 2 times a day. Duration of treatment is 3-4 days.

Like all non-steroidal anti-inflammatory drugs, Oki should not be used for a long time - a maximum of several days. If there is no positive result, consult a doctor.

If you accidentally swallow a little solution while rinsing, there is no need to worry. The dose is calculated in such a way that if ingested it cannot cause any harm.

It is better to use the solution half an hour after eating, having thoroughly brushed your teeth before the procedure.

For proper storage of Oka, the ambient temperature should not exceed 25 degrees. Giving a bottle of medicine as a toy to small children is strictly prohibited.

Gargling with Oki for sore throat and dental problems gives almost instant results.

The pain quickly subsides, tissue inflammation goes away, and swelling goes away. Considering that the concentration of the active substance in the solution is small, it does not last long. However, gargling more than 2 times a day is not recommended.

There are a lot of positive reviews about this product. The drug is effective and easy to use. The attached instructions contain more detailed information about the medicine "Oki".

Almost everyone, at least once in their life, has encountered a very severe sore throat, which subsides for a short period of time only after taking painkillers and is very difficult to treat. Such a painful manifestation of viral infections (which already significantly worsen the patient’s condition, causing severe intoxication) leads to refusal of food and insufficient fluid intake, which causes a slowdown in recovery. In order to relieve the inflammatory process and eliminate high-intensity pain, a pharmacy rinse called OCI is often used today. It is very effective for all major throat diseases, but in some patients - due to the characteristics of their body - it turns out to be ineffective or completely useless. For this reason, when treating with this drug, you must carefully monitor your well-being, and if even a slight improvement is not observed within 2 days, you should consult a doctor to select another medicine. In addition, due to the fact that OKI has many contraindications, it is better not to prescribe this rinse for yourself. In the same case, if there is no opportunity to visit a doctor and it is decided to use OKI, you must strictly follow the instructions included with the medicine, without violating the dosage and duration of treatment, and also without ignoring contraindications.

The drug contains only one medicinal component - the non-steroidal anti-inflammatory drug ketoprofen. With regular use, the drug provides a lasting analgesic and anti-inflammatory effect. According to the results of studies that were conducted before the medicine hit the market, it was proven that it relieves pain several times better than analgesics taken orally in the form of tablets and capsules. The duration of the analgesic effect reaches 12 hours.

The medicine does not fight pathogens, as it does not have an antimicrobial effect. Rinsing OCI only affects inflammation, stopping the production of the cyclooxygenase enzyme and thereby stopping the infiltration process. Unpleasant sensations in the throat with proper use of gargling usually disappear within 2-3 days. The drug can be used together with antiseptics.

Indications for the use of rinsing OKI are diseases of the pharynx, in which pain and acute inflammation develop. The following ailments are successfully treated with this medicine:

  • angina;
  • tonsillitis;
  • pharyngitis;
  • laryngitis;
  • inflammation of the vocal cords;
  • ulcerative lesions of the pharyngeal mucosa.

If the drug works well for the patient, positive changes in his condition appear already on the second day of therapy, and this means that it can be continued.

There are quite a lot of prohibitions on using the medicine. Compliance with them is necessary, since otherwise the patient’s health can be seriously harmed. Contraindications for treatment with OCI are:

  • disturbances in the process of blood clotting;
  • ulcerative lesions of the stomach;
  • ulcerative lesions of the gastrointestinal tract;
  • bronchial asthma;
  • chronic kidney disease;
  • Whipple's disease;
  • children under 6 years of age;
  • breastfeeding period;
  • late stages of pregnancy.

During the 1st and 2nd trimesters (in the first 6 months of pregnancy), the use of OCI rinsing is possible only if the benefit to the mother exceeds the expected harm to the unborn child and there is no possibility of therapy with another drug that is safe for the fetus. In this case, treatment is carried out solely for medical reasons and subject to strict adherence to medical recommendations.

If the drug is accidentally swallowed, there is a high probability that it will provoke an acute ulcerative process in the stomach or intestines. Therefore, in such a situation, you need to do the following: if the portion of what you swallowed is large, consult a doctor immediately; with a small dose, induce vomiting by drinking warm water.

In some patients, the use of OKI rinsing may be accompanied by side effects, the appearance of which is a signal to discontinue therapy. Most often, patients experience the following adverse events:

  • bronchospasm;
  • swelling of the larynx of varying intensity;
  • swelling of the tongue;
  • severe hoarseness of voice.
It is prohibited to ignore such consequences of therapy, since further treatment of a sore throat with OKI gargles in this case can lead to serious complications requiring immediate medical intervention. This especially applies to the first three manifestations.

Since the medicine is produced in the form of a spray, you will have to prepare rinses from it. Complete with the drug in the package there is a measuring cup, which is used to obtain the composition for rinsing. Take 100 ml of warm, but not hot water (temperature about 40 degrees) into this container and, turning the sprayer on the OKI bottle to the “Open” position and pressing the dispenser, inject the drug into the water. One click on the dispenser allows you to add 2 ml of medicine to the water. For adults, 10 ml of the drug is required per 100 ml of water, and therefore 5 pumps must be made. Having mixed the composition well, rinse it immediately. Depending on how severe the throat inflammation is, the procedure is carried out 1 or 2 times a day. The throat is treated with a single liquid taken into the mouth for 40 seconds. If the throat disease is particularly severe, the doctor may prescribe treatment of the throat with OKI spray between rinses (1 press of the dispenser for 1 irrigation).

Particular attention should be paid to gargling in people with mental retardation and severe mental illness. These patients may not be able to correctly complete the entire procedure without assistance, and therefore they need to be monitored throughout its entire duration.

For children, depending on their age, the concentration of the solution with the drug required for rinsing will be significantly less. You can gargle with OKI only from the age of 6 years. For a younger child, such rinsing is dangerous, since even in a small dosage it will lead to severe intoxication. When preparing a rinse solution for children aged 6 to 10 years, dissolve 4 ml of the medicinal composition in 100 ml of warm water (2 pumps of the dispenser). For patients aged 10 to 15 years, the medicine is diluted in an amount of 6 ml (3 pumps of the dispenser) per 100 ml of water.

Before the procedure, the child should be explained that swallowing the medicine is unacceptable, and if this happens, he should immediately contact an adult so that they can urgently provide him with the necessary help. Throughout rinsing, children under 10 years of age need to be under constant adult supervision. 1 procedure requires 100 ml of solution. After taking the medicine into your mouth, use it to treat your sore throat for 30 seconds. The procedure is carried out once a day for 5–7 days. If the child complains that rinsing causes severe discomfort, it should be abandoned.

Gargling OKI allows you to cure a sore throat in a short time, but, unfortunately, not for everyone; and therefore, ultimately, the patient himself must decide whether to purchase this expensive drug for therapy or replace it with a cheaper drug.

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DocVita

Active substance: ketoprofen

ATX code: A01AD11

KFG: NSAIDs for topical use in ENT practice and dentistry

ICD-10 codes (indications): J02, J03, J04, K05, K12, Z51.4

Reg. number: P N010598/03

Registration date: 06/09/10

Owner reg. cert.: DOMPE (Italy)

DOSAGE FORM, COMPOSITION AND PACKAGING

? The solution for topical use is transparent, green in color, with a characteristic mint odor.

Excipients: glycerol mg, ethanol - 0.05 ml, methyl parahydroxybenzoate - 1.5 mg, mint flavor - 3 mg, menthol - 0.7 mg, sodium saccharinate - 2 mg, brilliant green - 0.16 mg, sodium hydrogen phosphate - 22 mg, purified water - 1 ml.

150 ml - plastic bottles (1) with an injection dispenser (2 ml), complete with a dosing glass - cardboard packs.

INSTRUCTIONS FOR USE FOR SPECIALISTS.

The description of the drug was approved by the manufacturer in 2012.

NSAIDs. It has anti-inflammatory, analgesic and antipyretic effects. By inhibiting COX-1 and COX-2, it inhibits the synthesis of prostaglandins. It has anti-bradykinin activity, stabilizes lysosomal membranes and delays the release of enzymes from them that contribute to tissue destruction during chronic inflammation. Reduces the release of cytokines, inhibits the activity of neutrophils.

The drug does not have an antibacterial effect.

After using 160 mg of ketoprofen lysine salt in the form of a solution for topical use, the concentration of ketoprofen in plasma is very low (less than 400 ng/ml) and therefore insufficient for a pronounced systemic effect.

Symptomatic treatment of inflammatory diseases of the oral cavity, pharynx and larynx, including:

As analgesia during dental procedures.

The drug is used topically as a rinse. Adults should do 2 rinses/day. For 1 rinse, use 10 ml of Oka solution (5 injections). Adolescents over 12 years of age should use no more than 6 ml (3 injections) per rinse. Children from 6 to 12 years old should use 4 ml of Oka solution (2 injections) per 1 rinse.

The rinse solution should be prepared in the cup included with the package, half filled with drinking water (100 ml). One click on the dispenser-injector (1 injection) corresponds to 2 ml of Oka solution.

Rules for preparing the solution

You should bring the sprayer into the functional position, turning the nozzle towards the inscription “open”, inject into the supplied plastic cup by pressing the sprayer all the way (injections are repeated until the dose prescribed by the doctor is reached), dissolve the injected dose in 100 ml of drinking water (half a plastic cup) .

If the drug is swallowed, systemic side effects may develop.

- hypersensitivity to ketoprofen or other NSAIDs.

The drug should be used with caution in cases of gastric and duodenal ulcers in the acute phase, ulcerative colitis in the acute phase, Crohn's disease, diverticulitis, peptic ulcers, hemophilia and other blood clotting disorders, in the third trimester of pregnancy, during lactation (breastfeeding), as well as in children under 6 years of age.

The use of Oki in the third trimester of pregnancy is not recommended. In the first and second trimesters of pregnancy, Oki should be used with caution and under the supervision of a physician.

If it is necessary to use the drug during lactation, breastfeeding should be discontinued.

Long-term use of the drug may lead to sensitization. In this case, you should stop using the drug and select adequate treatment methods.

Accidental ingestion of rinse solution does not lead to serious consequences, because... a single dose for rinsing contains 160 mg of ketoprofen lysine salt, which corresponds to the dose intended for oral administration.

Currently, no cases of overdose with Oki have been reported.

No drug interactions have been identified with Oki.

The drug is approved for use as a means of OTC.

The drug should be stored out of the reach of children at temperatures up to 25°C. Shelf life – 2 years.

Source: http://docvita.ru/Details/OKI-rastvor.html

Home First Aid Kit

Oki (Ketoprofen) solution for topical use

Instructions and description of the drug

Drug name: OKI

International name: ketoprofen (ketoprofen)

KFG: NSAIDs for topical use in ENT practice and dentistry

Owner reg. certificates: DOMPE SpA (Italy)

DOSAGE FORM, COMPOSITION AND PACKAGING:

◊ The solution for topical use is transparent, green in color, with a characteristic mint odor.

1 ml - ketoprofen lysine salt - 16 mg

Excipients: glycerol mg, ethanol - 0.05 ml, methyl parahydroxybenzoate - 1.5 mg, mint flavor - 3 mg, menthol - 0.7 mg, sodium saccharinate - 2 mg, brilliant green - 0.16 mg, sodium hydrogen phosphate - 22 mg, purified water - 1 ml.

NSAIDs. It has anti-inflammatory, analgesic and antipyretic effects. By inhibiting COX-1 and COX-2, it inhibits the synthesis of prostaglandins. It has anti-bradykinin activity, stabilizes lysosomal membranes and delays the release of enzymes from them that contribute to tissue destruction during chronic inflammation. Reduces the release of cytokines, inhibits the activity of neutrophils.

After using 160 mg of ketoprofen lysine salt in the form of a solution for topical use, the concentration of ketoprofen in plasma is very low (less than 400 ng/ml) and therefore insufficient for a pronounced systemic effect.

Symptomatic treatment of inflammatory diseases of the oral cavity, pharynx and larynx, including:

The drug is used topically as a rinse. Adults should do 2 rinses/day. For 1 rinse, use 10 ml of Oka solution (5 injections). Adolescents over 12 years of age should use no more than 6 ml (3 injections) per rinse. Children from 6 to 12 years old should use 4 ml of Oka solution (2 injections) per 1 rinse.

PREGNANCY AND LACTATION

The use of Oki in the third trimester of pregnancy is not recommended. In the first and second trimesters of pregnancy, Oki should be used with caution and under the supervision of a physician.

If it is necessary to use the drug during lactation, breastfeeding should be discontinued.

Long-term use of the drug may lead to sensitization. In this case, you should stop using the drug and select adequate treatment methods.

Currently, no cases of overdose with Oki have been reported.

No drug interactions have been identified with Oki.

STORAGE CONDITIONS AND EXPIRATION DATES

The drug should be stored out of the reach of children at temperatures up to 25°C. Shelf life – 2 years.

Source of information: VIDAL Directory "Medicines in Russia".

The description of the drug is not intended to prescribe treatment without the participation of a doctor.

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Oka solution instructions for use

Instructions for use:

Prices in online pharmacies:

OCI is a non-steroidal anti-inflammatory drug (NSAID).

Release form and composition

  • Rectal suppositories: torpedo-shaped, from white to light yellow (5 pieces in strips, 2 strips in a cardboard pack);
  • Solution for topical use: green, transparent, with a characteristic smell of mint (150 ml in plastic bottles equipped with an injection dispenser (2 ml), in a cardboard pack 1 bottle complete with a dosage cup);
  • Granules for preparing a solution for oral administration: white to pale yellow in color, have a characteristic mint odor (2 g each in three-layer double-volume sachets, 12 or 20 sachets in a cardboard pack).

The active substance of the drug is ketoprofen lysine salt:

  • 1 suppository – 60 or 160 mg;
  • 1 ml of solution – 16 mg;
  • 1 packet of granules – 80 mg.
  • Suppositories: semi-synthetic glycerides;
  • Solution for topical use: glycerol, sodium saccharinate, methyl parahydroxybenzoate, ethanol, sodium hydrogen phosphate, purified water, menthol, brilliant green, mint flavor;
  • Granules: colloidal silicon dioxide, sodium saccharinate, polyvinylpyrrolidone, sodium chloride, mannitol, ammonium glycerate, mint flavor.

Indications for use

Symptomatic treatment of inflammatory processes accompanied by pain and fever, including:

  • Inflammatory diseases of the upper respiratory tract in adults and children over 6 years of age;
  • Rheumatic and inflammatory diseases of the joints, such as osteoarthritis, spondyloarthritis, gouty arthritis, inflammation of the periarticular tissues, rheumatoid arthritis in adults and children over 6 years of age;
  • Relief of postoperative pain in children over 6 years of age.

Solution for topical use

  • Symptomatic treatment of inflammatory diseases of the oral cavity, larynx and pharynx, including glossitis, gingivitis, stomatitis, laryngitis, tonsillitis, pharyngitis, periodontopathy, chronic periodontal disease, aphthae;
  • Analgesia during dental procedures.

Granules for preparation of suspension for oral administration

  • Symptomatic treatment of inflammatory processes accompanied by pain and fever in adults and children over 6 years of age;
  • Relief of postoperative pain in children over 6 years of age.

Contraindications

For all dosage forms:

  • Aspirin triad;
  • Hypersensitivity to the components of the drug or other NSAIDs.

Additionally for rectal suppositories and granules:

  • Ulcerative colitis in the acute phase;
  • Peptic ulcer of the stomach and duodenum in the acute phase;
  • Peptic ulcer;
  • Diverticulitis;
  • Crohn's disease;
  • Blood clotting disorders (including hemophilia);
  • Severe renal dysfunction;
  • Chronic renal failure;
  • Children under 6 years of age;
  • III trimester of pregnancy;
  • Lactation.

Rectal suppositories and granules are prescribed with caution in the following cases:

  • Anemia;
  • Bronchial asthma;
  • Hyperbilirubinemia;
  • Liver failure;
  • Dehydration;
  • Chronic heart failure;
  • Edema;
  • Sepsis;
  • Diabetes;
  • Alcoholism;
  • Alcoholic cirrhosis of the liver;
  • Tobacco smoking;
  • Glucose-6-phosphate dehydrogenase deficiency;
  • Arterial hypertension;
  • Blood diseases, including leukopenia;
  • Stomatitis;
  • I and II trimesters of pregnancy;
  • Elderly age.

The topical solution is prescribed with caution in the following cases:

  • Peptic ulcer of the stomach and duodenum in the acute stage;
  • Exacerbation of ulcerative colitis;
  • Crohn's disease;
  • Peptic ulcer;
  • Diverticulitis;
  • Hemophilia and other blood clotting disorders;
  • Children under 6 years of age;
  • III trimester of pregnancy;
  • Lactation.

Directions for use and dosage

Adults and adolescents over 14 years of age are prescribed suppositories at a dose of 160 mg - 1 pc. 2-3 times a day. The maximum permissible daily dose is 480 mg (3 suppositories). The suppository should be inserted into the rectum; before use, it is recommended to moisten it with water to avoid burning.

For elderly patients, the daily dose is reduced by 2 times.

Children aged 6-12 years (with a body weight of at least 30 kg) are prescribed suppositories at a dose of 60 mg - 1 pc. 1-2 times a day, for children up to 1-3 times a day. The maximum daily dose is 5 mg/kg.

A dose reduction is required in patients with impaired renal and hepatic function.

Solution for topical use

The drug in this dosage form is used as a rinse 2 times a day.

A single dose (per 1 rinse) for adults is 10 ml of solution (5 sprays), adolescents over 12 years old - 6 ml (3 sprays), children 6-12 years old - 4 ml (2 sprays).

1 injection (one click on the dispenser) corresponds to 2 ml of solution. The rinse solution should be prepared in the glass included in the kit. To do this, you need to fill the glass halfway with drinking water (100 ml), turn the spout towards the “open” sign and inject the drug into the water, pressing the spray nozzle all the way, until the dose prescribed by the doctor is reached.

Granules for oral suspension

A suspension is prepared from the granules, which is taken orally during meals.

To receive 1 full dose (80 mg), you must open one sachet along the line marked “full dose”, ½ dose (40 mg) – along the line marked “half dose”. Pour the contents into a glass half filled with water.

Adults and adolescents over 14 years of age are prescribed 80 mg 3 times a day, children 6-14 years old - 40 mg 3 times a day.

For elderly patients, the dose is determined by the attending physician (usually it is reduced by 2 times).

Side effects

When using OKI in the form of rectal suppositories and granules, the following side effects are possible:

  • From the digestive system: stomatitis, diarrhea, abdominal pain, melena, duodenitis, gastritis, esophagitis, hematomesis, erosive and ulcerative lesions of the gastrointestinal tract, enlarged liver, increased activity of liver enzymes, increased bilirubin levels, hepatitis, liver failure;
  • From the central nervous system: tremor, mood swings, hyperkinesia, anxiety, general malaise, hallucinations, dizziness, irritability, visual impairment;
  • From the urinary system: edema, cystitis, painful urination, hematuria;
  • From the hematopoietic system: decreased prothrombin time, lymphangitis, thrombocytopenia, leukocytosis, thrombocytopenic purpura, leukocytopenia, vasculitis, enlarged spleen;
  • From the cardiovascular system: chest pain, tachycardia, hypotension or hypertension, peripheral edema, syncope, pallor;
  • From the respiratory system: rhinitis, sensation of laryngeal spasm, laryngeal edema, dyspnea, bronchospasm, laryngospasm;
  • Dermatological reactions: maculopapular rash, itching, erythematous exanthema;
  • Allergic reactions: urticaria, anaphylactoid reactions (periorbital edema, pharyngeal edema, swelling of the oral mucosa), erythema multiforme, angioedema;
  • Other: increased sweating, menstrual irregularities, conjunctivitis;
  • Local reactions when used rectally: heaviness, itching and burning in the anorectal area, exacerbation of hemorrhoids.

When using the solution for topical use (as a rinse), allergic reactions are possible. If the drug is swallowed, there is a risk of developing systemic side effects.

special instructions

With long-term treatment, sensitization (increased sensitivity of the body) may develop, which requires discontinuation of the drug and appropriate therapy.

Rectal granules and suppositories

During treatment, it is necessary to periodically monitor the peripheral blood picture, the functional state of the kidneys and liver. Patients with impaired renal and hepatic function require dose reduction and careful monitoring.

Ketoprofen can mask signs of infectious diseases, and in patients with bronchial asthma it can cause an attack of suffocation.

Patients who are indicated for a study to determine 17-ketosteroids must discontinue the drug 48 hours before.

If the condition worsens, treatment should be discontinued.

During the period of use of OKI in the form of suppositories and granules, it is recommended to refrain from performing potentially hazardous types of work that require quick reactions and high concentration of attention.

Drug interactions

Possible interaction reactions when using OKI in the form of granules and rectal suppositories:

  • Uricosuric drugs, antihypertensive drugs, diuretics: their effectiveness decreases;
  • Anticoagulants, antiplatelet agents, fibrinolytics, ethanol: their effect is enhanced;
  • Mineralocorticoids, glucocorticoids, estrogens: their side effects increase;
  • Oral anticoagulants, heparin, thrombolytics, antiplatelet agents, cefamandole, cefoperazone, cefotetan: the risk of bleeding increases;
  • Insulin and oral hypoglycemic drugs: their hypoglycemic effect is enhanced (dose recalculation required);
  • Sodium valproate: platelet aggregation is impaired;
  • Nifedipine, verapamil, methotrexate, lithium: their concentration in plasma increases;
  • Non-steroidal anti-inflammatory drugs, glucocorticosteroids, ethanol, corticotropin: the risk of ulcers, gastrointestinal bleeding and renal dysfunction increases;
  • Inducers of microsomal oxidation in the liver (rifampicin, flumecinol, phenylbutazone, phenytoin, tricyclic antidepressants, barbiturates, ethanol): the metabolism of ketoprofen increases;
  • Antacids and cholestyramine: absorption of ketoprofen is reduced.

No drug interactions have been identified with OKI in the form of a solution for topical use.

Terms and conditions of storage

Store at temperatures up to 25 ºС out of the reach of children.

The shelf life of solution granules for topical use is 2 years, rectal suppositories for adults (160 mg) are 5 years, rectal suppositories for children (60 mg) are 3 years.

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Oki 160 mg No. 10 rectal suppositories

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