Eucazoline for children instructions for use

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Spray "Evkazolin Aqua": instructions for use, analogues and reviews

Each of us has probably experienced nasal congestion and runny nose at least once in our lives. It becomes difficult to breathe, and life no longer seems so comfortable.

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This condition interferes with normal sleep and leading a normal lifestyle. In this article we will look at what Evkazolin Aqua anti-runny nose spray is. Instructions for use, analogues and reviews are listed in this article. Therefore, after reading the information provided, you can make the right choice for yourself.

Description of the drug

The nasal medicine "Evkazolin Aqua" is in the form of a spray intended for irrigation of the nasal cavity. It is this form of release that allows the active substances to be delivered to the right place as quickly as possible. At the same time, droplets of healing liquid will be able to get into even the most inaccessible places. However, if necessary, you can purchase this product in the form of drops. The drug is able to have a vasoconstrictor effect, as well as eliminate swelling and hyperemia.

The drug "Evkazolin Aqua", the instructions for use of which are described below, is considered so effective because it contains xylometazoline. In addition, the composition also includes eucalyptus oil, which has an antiseptic effect. This component will help prevent the infection from spreading further.

Doctors do not recommend using the spray for a long time, since after a few days of use the body simply begins to get used to it. In this case, side effects may begin to appear.

What is the principle of operation

The drug "Evkazolin Aqua", instructions for use for which are included in each cardboard package, is capable of relieving nasal congestion for a long time. It becomes easier to breathe, as the secretion of mucous secretion, as well as hyperemia, decreases. In addition, the blood flow of the vessels located in the nasal cavity itself decreases. The eucalyptus oil contained in the composition can have a moisturizing and anti-inflammatory effect, which speeds up the healing process.

The drug does not have a systemic effect on the body. The first effect after use can be noticed within ten minutes. It really does become easier to breathe, and patient reviews confirm this. If the dosage was observed correctly, it means that the drug will penetrate the mucous membrane of the nasal cavity in a very small amount.

For rhinitis, the drug can alleviate the condition for seven to eight hours, after which all the symptoms of this disease will return again. "Evkazolin Aqua" instructions for use are positioned as a very effective remedy that can relieve you of unpleasant symptoms. However, it does not have a significant therapeutic effect.

In what cases can it be used?

Most often, this drug is prescribed to eliminate the symptoms of rhinitis. In this case, the disease can have both an acute and chronic form. In any case, the patient will complain of a runny nose, nasal congestion, dizziness and headache, and sometimes increased body temperature. Please note that the chronic form of rhinitis is more dangerous than the acute form. Therefore, if you notice that the disease periodically recurs, be sure to go to the hospital.

So, in what cases does the instruction for use recommend using “Evkazolin Aqua” (spray):

- all types of rhinitis, including allergic;

- the presence of inflammatory processes in the middle ear, as well as with sinusitis;

— the remedy is recommended by doctors for hay fever.

This medicine can also be used before medical examinations in the nasal cavity.

"Evkazolin Aqua" (spray): instructions for use

The product in the form of a spray is very convenient to use, since you can use it at absolutely any time in absolutely any place. The drug is sprayed evenly, so all areas of the nasal cavity will be exposed to it. In order for the product to have the maximum therapeutic effect, before using it you need to thoroughly clean the nasal passages of the mucus accumulated there. The medicine should be squirted into each nostril. To do this, bring the bottle to your nose and hold it in an upright position. As soon as you press the dispenser, immediately take a deep breath. Using this technique, you can carefully distribute the medication over the entire inner surface of the nose.

The instructions recommend using Evkazolin Aqua spray only if the patient has severe nasal congestion and it is very difficult to breathe. The drug can be used by adults, as well as children over twelve years of age. One spray should be administered into each nostril. The maximum number of injections that can be performed per day is three. Do not increase the dosage under any circumstances. This will lead to the development of side effects.

Important information

Experts warn that if you use this spray for more than seven days, addiction to it will begin to develop. But solving this problem will not be so easy. In addition, the product does not have a therapeutic effect. It will only make breathing easier and reduce swelling. If you use the product for more than a week, there is a risk of developing a disease such as drug-induced rhinitis. You simply won’t be able to get rid of it at home.

"Evkazolin Aqua": instructions for use during pregnancy

Typically, this drug is prescribed to pregnant women extremely rarely, however, according to reviews from pregnant women, the drug is really effective even during pregnancy.

There are no side effects. Under no circumstances should you start self-medicating. If the doctor has confirmed that the nasal spray will not have a negative effect on you and your unborn baby, then you can safely use it.

Use for children

"Evkazolin Aqua" instructions for use for children recommend using only in the form of drops. This type of drug can be prescribed to children over six years of age. Drops, just like the spray, work well for nasal congestion and relieve swelling. However, they do not have a healing effect. Therefore, before using them, be sure to consult your pediatrician.

Place two or three drops into each nostril. It is best to do this in a supine position. However, if this is not possible, then you just need to tilt your head back a little. This procedure should be carried out three or four times a day for several days.

Are there any side effects when using

According to patient reviews, Evkazolin Aqua drops (instructions for use are described in this article) can lead to side effects. Some patients complain of excessive dryness in the nasal area, as well as burning and stinging. If you use the product for too long, you may experience a headache, dizziness, and an increase in blood pressure.

Under no circumstances should the product be used by patients who are hypersensitive to its constituent components.

Analogs

The drug "Evkazolin Aqua" has a huge number of similar products. They all have similar effects, but seek advice from an experienced professional before using them. So, pay attention to the products that can replace the Eucazolin Aqua spray:

- “Rinostop” and many others.

Reviews from patients and doctors

The drug "Evkazolin Aqua" is indeed very popular and popular today. Many doctors prescribe this drug to their patients because they are confident in its effectiveness.

People who decide to try the effects of this spray agree that nasal congestion disappears almost instantly after using it. However, after a few hours the injection procedure must be repeated.

Start treatment on time, and then you can easily cope with any illness.

Source: http://www.syl.ru/article/337478/sprey-evkazolin-akva-instruktsiya-po-primeneniyu-analogi-i-otzyivyi

EUCAZOLINE INSTRUCTIONS

Prices for EUCAZOLINE

It acts predominantly locally; when used in therapeutic doses, it is absorbed through the mucous membranes in small quantities. The action begins a few minutes after application and lasts for 8–10 hours.

Adults and children over 12 years old - 1-2 drops 2-3 times a day in each nasal passage.

Children aged 7 to 12 years - 1 drop in each nasal passage 2-3 times a day. The drug is used for 5–7 days.

Adults and children over 12 years of age are prescribed 1 injection 2-3 times a day in each nasal passage. The duration of use of the drug is 5–7 days.

Use during pregnancy and lactation: in therapeutic doses the drug acts locally and does not have a systemic effect, therefore the use of the drug in therapeutic doses in this population is not contraindicated.

In patients with hypertension, hyperthyroidism, pathology of the cardiovascular system, and diabetes mellitus, the drug should be used with caution, taking into account the possibility of developing hypertension, tachycardia and arrhythmia.

Reviews EUCAZOLINE

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Questions and answers

Articles on the topic “Rhinitis”

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Reviews about medicine. Catalogue of medicines, pharmacies, hospitals, physicians base.

Source: http://www.medcentre.com.ua/medicamenty/evkazolin.html

Evkazolin - detailed instructions

The composition of the drug eucazoline (1 g) includes the following substances:

  • xylometazoline hydrochloride (xylometazoline) - 1 mg,
  • Eucalyptus oil,
  • propylene glycol,
  • polyethylene glycol – 1500,
  • polysorbate – 20,
  • hypromelose,
  • sodium hydrogen phosphate,
  • povidone,
  • edetate disodium,
  • dodecahydrate,
  • potassium dihydrogen phosphate,
  • benzalkonium chloride,
  • water for injections.

Evkazoline instructions

The drug is available in the form of a spray and drops and is prescribed for diseases of the nasal cavity; it belongs to the class of sympathomimetics. The instructions supplied with the drug eucazoline describe the action of the product and methods of its use. The drug is aimed at eliminating the symptoms associated with the disease of the nasal cavity and has a local effect, a small amount of it is absorbed through the mucous membranes of the nose. Evkazoline begins to act approximately 6-9 minutes after application, the duration of action is up to 6 hours.

Indications for use of the drug eucazoline

  • hay fever,
  • allergic sinusitis,
  • allergic rhinitis,
  • cold,

The drug is used to eliminate symptoms of nasal congestion and difficulty breathing, in order to reduce the degree of swelling of the nasal mucosa. The medicine is also used to treat otitis media (otitis media), diagnosis of the nasal cavity also requires prior use of this medicine.

Contraindications for use

  • hyperthyroidism,
  • coronary asthma,
  • angle-closure glaucoma,
  • transsphenoidal hypophysectomy,
  • transoral or transnasal surgical interventions, accompanied by exposure of the lining of the brain (dura),
  • treatment with MAO inhibitors, 14 days after their use.

This drug is not recommended to be prescribed continuously and for a long time; there should be no short intervals between courses of treatment; the duration of treatment should not be more than 10 days from the start of therapy. During long-term use of the medicine, the effect may be the opposite. It is not recommended to exceed the dose of the medicine, this is especially dangerous for older people. If there is a history of hypersensitivity to the components of the drug, as well as insomnia, tremor, dizziness, cardiac arrhythmia, hypertension, the drug is not prescribed. People suffering from diseases of the cardiovascular system, hypertension, diabetes, thyroid diseases, and difficulty urinating require constant monitoring while using the drug. There may be an increase in intraocular pressure, since the medicine has a vasoconstrictor property. The drug package should only be used by one person to avoid the spread of infection.

Since eucazoline is not able to affect the ability to drive a vehicle when consumed in normal acceptable doses, it is prescribed to vehicle drivers and people whose work involves driving and complex machinery. At the same time, this medicine must be taken with extreme caution, since visual impairment, which is temporary, cannot be ruled out. Evkazolin Aqua is not recommended for children under 10 years of age. In the case of uncontrolled and long-term use of the drug, the appearance of symptoms such as increased blood pressure, nausea, depression, blurred vision, headache, and dryness in the nasal cavity is possible. If negative symptoms occur, you should immediately stop using the medication; in this condition, the doctor prescribes tropafen, phentolamine (α-blockers), sympatholytics, and eucazoline antagonists. In case of accidental ingestion of the drug, you must immediately resort to gastric lavage, take a laxative, enterosorbent, prescribe α-blockers, and carry out therapy aimed at eliminating negative symptoms.

Eucazoline during pregnancy or breastfeeding

It is not recommended to take eucazoline during pregnancy, as adverse reactions are possible. Since at the moment the fact that the substances contained in the drug penetrate into breast milk has not been sufficiently studied, it is not recommended to take eucazoline while breastfeeding. The drug is prescribed if the therapeutic effect outweighs the risks for the infant.

Evkazoline aqua

The drug contains xylometazoline hydrochloride, which is classified as an α-adrenergic agonist (non-selective). During use, swelling and hyperemia of the nasal mucosa are reduced, nasal breathing is improved, and the secretion of exudate is reduced. Evkazolin Aqua contains xylometazoline hydrochloride in an amount of 1 mg, disodium phosphate dodecahydrate, water for injection and other substances.

The contents of the drug during use of the bottle with the medicine are sprayed with an aerosol stream, the smell of the drug is specific. Product release form: nasal spray, related to decongestant drugs intended for topical use. The drug is prescribed in case of rhinitis, sinusitis, hay fever, as well as in the preparatory period before diagnostic procedures regarding the nasal passages.

Children over 12 years of age and adults can use eucazoline Aqua (0.1% solution) two or three times a day, 1 injection dose (in both nasal passages). In case of overdose and in case of intolerance to the drug, symptoms such as increased secretion of exudate, atrophy of the mucous membrane, tachycardia, vomiting, headache, insomnia, blurred vision, and allergies may occur. Long-term use of the drug may lead to a lack of therapeutic properties or a decrease in them. Evkazolin Aqua is not prescribed for the following diseases:

  • atrophic form of rhinitis,
  • hypersecretion of the thyroid gland,
  • closed glaucoma,
  • hypertension,
  • intolerance to the components of the drug,
  • age under 12 years.

Evkazoline spray

The medicine is available in a bottle equipped with a special nozzle for spraying. Before using eucazoline spray, you need to warm the medicine in your hands for a few minutes. The drug is recommended for adults and children over 10 years of age. For 10 days, the product is injected daily into each nasal passage up to four times (according to the th injection dose). It is not recommended to use this medication on your own without consulting a doctor.

Evkazoline price

This drug does not require a prescription at the pharmacy network and is sold freely. For the drug eucazoline, the price is set in each individual pharmacy and can vary within a slight range.

Evkazoline reviews

The drug must be used on the recommendation of the treating doctor; it is prescribed with extreme caution to persons suffering from diseases of the cardiovascular system, in case of metabolic disorders, thyroid diseases and hypertension. Athletes are advised to use the drug with extreme caution, as there may be some change in the speed of the psychomotor reaction. Before using the drug, you should consult your doctor.

Source: http://nasmork-rinit.com/meditsinskie-preparaty/206-evkazolin-razvernutaya-instruktsiya

Eucazolin-aqua

Active substance:

Content

Pharmacological groups

Nosological classification (ICD-10)

Compound

Description of the dosage form

Transparent, slightly yellowish liquid with a specific odor.

pharmachologic effect

Pharmacodynamics

Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with an α 2 -adrenomimetic effect; it has a rapid and prolonged vasoconstrictor effect on the vessels of the nasal mucosa, eliminating swelling and hyperemia of the mucous membrane. Facilitates nasal breathing during rhinitis. The action begins within a few minutes and lasts for several hours.

Pharmacokinetics

When applied topically, it is practically not absorbed; plasma concentrations are so small that they cannot be determined by modern analytical methods.

Indications for the drug Evkazolin Aqua

relief of symptoms of acute rhinitis of various etiologies, sinusitis;

auxiliary therapy for acute otitis media (to reduce swelling of the nasal mucosa);

preparing the patient for diagnostic procedures (rhinoscopy).

Contraindications

hypersensitivity to any component of the drug;

transsphenoidal hypophysectomy or a history of transnasal/transoral surgical interventions with exposure of the dura mater;

children's age (up to 12 years).

With caution: patients with cardiovascular diseases, diabetes mellitus, thyroid diseases (hyperthyroidism), patients who experience strong reactions when using adrenergic drugs, manifested in the form of insomnia, dizziness, tremor, cardiac arrhythmia, a tendency to increase blood pressure; patients with prostatic hyperplasia, women during lactation.

Use during pregnancy and breastfeeding

The drug should not be used during pregnancy.

It is not known whether xylometazoline is excreted in breast milk, so women who are breastfeeding should use the drug only when, in the opinion of the doctor, the expected benefit to the mother outweighs the potential risk to the baby.

Side effects

With frequent and/or prolonged use - irritation and/or dryness of the nasopharyngeal mucosa, burning and paresthesia of the nasal mucosa, sneezing, hypersecretion of the nasal mucosa, swelling of the nasal mucosa, palpitations, tachycardia, arrhythmias, increased blood pressure, headache , vomiting, insomnia, blurred vision, depression.

Interaction

Xylometazoline interacts with other drugs only when a resorptive effect occurs.

Other adrenergic agonists may enhance the effect of xylometazoline.

Adrenergic blockers and sympatholytics, CCBs weaken its effect.

The drug enhances the hypertensive effect of tricyclic antidepressants and MAO inhibitors.

Directions for use and doses

Intranasally. Adults and children over 12 years old - 1 injection into each nasal passage 3-4 times a day. The course of treatment depends on the course of the disease and should not exceed 5–7 days in a row.

After completing the course of treatment, the drug can be prescribed again only after a few days.

Overdose

Symptoms: decreased body temperature, bradycardia, increased blood pressure.

special instructions

The drug should not be used continuously for long periods (more than 7 days in a row).

The recommended doses of the drug should not be exceeded, especially when treating children and the elderly.

Use with caution while driving a vehicle or performing other types of work that require increased concentration and rapid psychomotor reactions.

Release form

Nasal spray, 1 mg/g. 10 g in a brown glass bottle, equipped with a dispenser pump with a spray for nasal use. Each bottle is placed in a cardboard pack.

Manufacturer

JSC "Farmak" 04080, Ukraine, Kiev, st. Frunze, 74.

Tel/fax: (),.

Representative office in Russia: Moscow, Kutuzovsky Ave., 65.

Tel.: ; .

Conditions for dispensing from pharmacies

Storage conditions for the drug Evkazolin Aqua

Keep out of the reach of children.

Shelf life of the drug Evkazolin Aqua

Do not use after the expiration date stated on the package.

Synonyms of nosological groups

Prices in Moscow pharmacies

The information is intended solely for comparing prices in stationary pharmacies operating in accordance with Article 55 of the Federal Law “On the Circulation of Medicines” dated April 12, 2010 N 61-FZ.

nasal spray 1 mg/g, 1 pc.

Farmak PJSC (Ukraine)

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Eucazoline Aqua

Description current as of 07/14/2015

  • Latin name: Eucazolin-aqua
  • ATX code: R01AA07
  • Active ingredient: Xylometazoline
  • Manufacturer: Farmak PJSC (Ukraine)

Compound

1 g of xylometazoline hydrochloride spray contains 1 mg.

Eucalyptus oil, benzalkonium chloride, propylene glycol, disodium edetate, macrogol, povidone, hypromellose, polysorbate, potassium dihydrogen phosphate, sodium hydrogen phosphate, water for injection, as excipients.

Release form

Nasal spray in a bottle dispenser - spray.

pharmachologic effect

Anticongestive (local vasoconstrictor).

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Evkazolin Aqua is a local vasoconstrictor used for rhinitis.

Xylometazoline has an α2-adrenomimetic effect - it quickly and for a long time constricts the vessels of the nasal mucosa, eliminates swelling and inflammation. This makes nasal breathing easier.

The eucalyptus oil included in the composition additionally has anti-inflammatory, antimicrobial, mild antispasmodic and moisturizing effects. The effect appears 5 minutes after application and lasts up to 10 hours.

Pharmacokinetics

Xylometazoline is almost not absorbed when applied topically, therefore its concentrations in the blood are low and cannot be determined by analytical methods.

Indications for use

Spray Evkazolin is used for:

Contraindications

Spray Evkazolin is not used for:

Side effects

Evkazolin Aqua may cause:

  • local reactions, manifested by burning, tingling, sneezing, decreased sense of smell, increased secretion of mucus, and with prolonged and uncontrolled use - atrophic changes in the mucosa;
  • general reactions with frequent use: rhythm disturbances, increased blood pressure, palpitations, headache, insomnia, blurred vision, depression.

Spray Evkazolin Aqua, instructions for use (Method and dosage)

The aerosol form of the drug is prescribed to children over 12 years of age and adults. Before administration, the nasal passages should be cleaned. The bottle sprayer with the nozzle is held vertically upward and inserted into the nasal passage. Keep your head straight, you should not tilt it back. While inhaling, inject the drug once. The injection interval is 8-12 hours.

The instructions for Evkazolin Aqua contain warnings: do not exceed the dose of the drug, and should not be used for more than 7 days in a row. Evkazoline can affect the speed of psychomotor reactions.

Overdose

Manifested by symptoms: bradycardia, increased blood and intraocular pressure, decreased body temperature, blurred vision, headache, emotional depression and irritability.

Symptomatic therapy is carried out.

Interaction

Evkazoline and other alpha-agonists should not be combined with sedatives.

Other adrenergic agonists enhance the effect of xylometazoline. It in turn enhances the ability of tricyclic antidepressants and MAO inhibitors to cause hypertension.

Terms of sale

Storage conditions

At a temperature of no more than 25 C.

Best before date

Analogs

Reviews

Many users note the advantages of using a spray compared to similar drops: the spray is more economical, the medicinal substance is evenly distributed over the surface of the mucous membrane, it is convenient to use in any conditions - at work and in public places. The drug acts quickly and effectively.

Xylometazoline is a decongestant with an average duration of action, which allows you to reduce the frequency of use and reduce it to 1-2 times a day. This is also noted as a positive quality of the drug. It is important that everyone who took it noted that after using the spray the mucous membrane does not dry out (due to the presence of eucalyptus oil and water).

With prolonged use, any decongestants can worsen a runny nose, cause a persistent deterioration in blood supply to the mucous membrane and cause its atrophy. Addiction to them quickly develops, which is expressed in a decrease or complete cessation of the effect. In this regard, many drugs are used for 3–5 days. Preparations containing essential oils, which include Evkazolin Aqua, Pinosol, Kameton, can be used for a longer period - up to 7 days.

It must be remembered that all vasoconstrictors for topical use can cause increased blood pressure and tachycardia. This is mentioned in reviews of Eucazoline Aqua. This fact limits its use in the elderly, patients suffering from arterial hypertension and thyrotoxicosis. For some users, the spray caused irritation of the nasal mucosa, a burning sensation in the nose and throat.

Price of Evkazolina Aqua, where to buy

You can buy it in many pharmacies in Moscow without a doctor’s prescription. Approximate price of Evkazoline 0.1% spray in bottles is 10 ml rubles.

  • Online pharmacies in Russia Russia
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Pharmacy24

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BIOSPHERE

Education: Graduated from the Sverdlovsk Medical School (1968 - 1971) with a degree in Paramedic. He graduated from the Donetsk Medical Institute (1975 - 1981) with a degree in epidemiologist and hygienist. He completed his postgraduate studies at the Central Research Institute of Epidemiology in Moscow (1986 - 1989). Academic degree - Candidate of Medical Sciences (degree awarded in 1989, defense - Central Research Institute of Epidemiology, Moscow). Completed numerous advanced training courses in epidemiology and infectious diseases.

Work experience: Work as head of the disinfection and sterilization department 1981 - 1992. Work as head of the department of especially dangerous infections 1992 - 2010. Teaching activity at the Medical Institute 2010 - 2013

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EUCAZOLINE AQUA

With frequent and/or prolonged use: irritation of the mucous membrane, burning, tingling, sneezing, dry nasal mucosa, hypersecretion.

Rarely: swelling of the nasal mucosa (more often with long-term use), palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disorders, visual disturbances.

With long-term use in high doses: depressive state.

Should not be used for a long time, for example, for chronic rhinitis. For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel.

Use in pediatrics

Xylometazoline should be prescribed with caution to children under 2 years of age (gel - up to 7 years).

To ask a question about the project or contact the editors, use this form.

Source: http://health.mail.ru/drug/eucazolinaqua/

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Eucazoline

Eucazoline is classified as a medicine that is used in the treatment of colds accompanied by a runny nose. The medication can be available in the form of a spray or nasal drops.

Produced by Farmak OJSC, Ukraine, Kyiv.

Eucazoline is available without a prescription; prior consultation with a specialist is advisable.

ATX code

Active ingredients

Indications for use Evkazolin

The external use medication Evkazolin is prescribed:

  • to facilitate breathing through the nose with rhinitis, rhinosinusitis, hay fever, accompanied by significant swelling of the mucous membranes of the nasal cavity and hypersecretion;
  • to reduce swelling of the nasopharyngeal tissues when diagnosed with otitis media;
  • as preparatory procedures for diagnostics and therapy of the nasal cavity.

Release form

Evkazolin can be produced in the form of a spray, in a glass bottle with a special dispenser (10 g), or in the form of drops, in a glass bottle with a nozzle for drip dosing (10 g). Each bottle is packed in individual cardboard packaging.

The active component of the drug is xylometazoline hydrochloride in an amount of 1 mg. Additional substances include: benzalkonium chloride, eucalyptus oil, propylene glycol, macrogol, povidone, etc.

Pharmacodynamics

Evkazolin is a medicine for the common cold for external use. The active substance xylometazoline can reduce the filling of the lumen of blood vessels with blood and relieve swelling of mucous tissues. The medication has a pronounced vasoconstrictor effect, reduces the degree of redness of tissue surfaces and the release of exudate, which helps restore normal nasal breathing.

Eucazoline effectively reduces the manifestations of the inflammatory process and inhibits the growth of microbial cells. Eucalyptus oil plays the role of a mild antispasmodic and moisturizer for the mucous membranes; in addition, eucalyptus is able to suppress the development of Staphylococcus aureus, Mycobacterium tuberculosis, the causative agent of dysentery and Trichomonas. Eucalyptus essential oils also have a relaxing and analgesic effect.

Pharmacokinetics

The medication cannot have any systemic effect on the body, since when applied topically, the absorption of the active components into the blood is extremely insignificant.

When used externally, the therapeutic effect is observed within the first minutes, with a total duration of action of up to 10 hours.

Use of Evkazoline during pregnancy

Due to the fact that the medication does not penetrate the systemic bloodstream, its use in standard dosages during pregnancy is allowed. Also, local use of the medication is allowed during the period of breastfeeding. There is no need to stop breastfeeding during treatment with the drug.

Contraindications

Contraindications to the use of Evkazolin are:

  • increased sensitivity of the body to the components of the drug;
  • increased intraocular pressure;
  • atrophy of the mucous tissues of the nasal cavity;
  • hypertension;
  • hyperthyroidism (thyrotoxicosis).

The drug in the form of a spray is used for children from 12 years of age.

The drip form of Evkazolin can be used from 7 years of age.

Side effects of Evkazoline

The drug has minimal side effects, which are quite rare. Among them:

  • tingling sensation and dryness in the nasal cavity;
  • urge to sneeze;
  • liquefaction and hypersecretion of exudate;
  • temporary deterioration of olfactory functions;
  • signs of atrophy of the mucous membranes;
  • cardiac disorders;
  • increased blood pressure;
  • allergic manifestations.

Long-term and unsystematic use of the drug can lead to a decrease in susceptibility to its properties.

Directions for use and doses

The drug is used externally:

  • Evkazoline spray - allows the active substance to be evenly distributed over the surface of the tissues of the nasal cavity. Can be prescribed to adults and children over 12 years of age. The spray is injected once into each nostril; the injection can be repeated after 8-10 hours;
  • Eucazoline in the form of drops - used from 7 years of age to 12 years - one drop in each nostril, with possible re-administration after 8-10 hours. Adults inject up to 2 drops into each nostril, the interval between administration of drops is 8-10 hours. Duration of treatment is up to one week.

Overdose

Significant excess of recommended dosages can provoke the development of visual dysfunction, hypertension, increased intraocular pressure, migraine, and drying of the nasopharyngeal mucosa. Long-term use of high doses of the drug can lead to the development of atrophy of mucous tissue at the injection site.

Treatment of overdose is carried out by prescribing sympatholytic drugs and α-blockers (for example, phentolamine). If necessary, symptomatic therapy is prescribed.

In case of accidental ingestion of a medication, gastric lavage, sorbent medications (activated carbon, sorbex) and, sometimes, laxatives (regulax, bisacodyl) are used.

Interactions with other drugs

The drug Evkazolin is capable of interacting with other medications only when the drug has a resorptive effect.

Drugs that excite adrenergic receptors (ephedrine, galazolin, naphthyzin, mezaton) can enhance the effects of Evkazoline.

β-adrenergic receptor blockers (adrenaline, norepinephrine), sympatholytic agents (octadine, reserpine) and calcium channel blockers (cinnarizine, verapamil, amlodipine) can weaken the effect of Eucazoline.

Tricyclic antidepressants (imipramine, azaphene) reduce their own activity when used simultaneously with Eucazoline.

The effect of combined use of Eucazoline with monoamine oxidase inhibitors (metralindole, selegiline) may be reduced.

Sympathomimetics should not be prescribed together with sedatives.

Storage conditions

It is recommended to store the drug in its original packaging at a temperature of 22-24°C, avoiding direct ultraviolet rays.

Best before date

Shelf life – up to 2 years.

Pharmacological group

pharmachologic effect

ICD-10 code

Manufacturer

Medical Expert Editor

Portnov Alexey Alexandrovich

Education: Kiev National Medical University. A.A. Bogomolets, specialty - "General Medicine"

Attention!

To make information easier to understand, these instructions for use of the drug “Evkazolin” have been translated and presented in a special form based on the official instructions for medical use of the drug. Before use, read the leaflet included directly with the medication.

The description is provided for informational purposes and is not a guide to self-medication. The need to use this drug, the prescription of the treatment regimen, methods and doses of the drug are determined solely by the attending physician. Self-medication is dangerous for your health.

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How to use Evkazoline nasal drops?

Each of us has repeatedly experienced discomfort due to difficulty breathing caused by a runny nose. Pathological changes in the mucous membrane of the nasal cavities affect sleep, reduce ability to work and significantly worsen the usual way of life. The pharmacological industry produces a sufficient number of different remedies for rhinitis. Their actions are aimed at eliminating the causative agent of infection and relieving swelling of the mucous membrane of the nasal passages.

One of the widely used sympathomimetic drugs in ENT practice is Evkazolin. This is a topical drug for nasal use. Evkazolin refers to vasoconstrictor drugs that have contraindications. Therefore, before use, consultation with a doctor is necessary.

Description of the drug

Eucazoline contains two active ingredients:

  1. Xylometazoline (alpha-adrenergic stimulant) has a pronounced vasoconstrictor ability, reduces swelling of the nasal mucosa, and eliminates hyperemia. Helps relieve redness of the skin near the nasal wings and reduce secretion.
  2. Eucalyptus oil softens the inner surface of the nasal passages. Helps relieve nasal spasm and congestion. It also has antibacterial and antiviral properties.

The excipients in Eucazoline include: propylene glycol, water, benzalkonium chloride.

The nasal drug is available in two forms, a spray (Evkazolin Aqua) and drops in the form of an oily yellowish substance. The drops are in a glass bottle with a volume of 10 grams (one in a cardboard box).

The package also includes a dropper insert and instructions for use. The product is stored in a dark place, out of reach of children, at a temperature of no more than 25 degrees, for 2 years from the date of production. Dispensed in pharmacies without a prescription.

Pharmacodynamics and pharmacokinetics

Eucazoline, a nasal remedy in the form of drops, thanks to its active substance, effectively affects the inflamed lining of the nasal sinuses, relieving swelling.

The drug prevents excessive filling of the lumens of the nasal vessels with blood.

Helps normalize breathing by reducing secretion production and vasoconstrictor action.

The use of the drug stops the inflammatory process and inhibits the growth of bacteria. Acts as an antispasmodic.

Moisturizes the mucous membrane of the nasal passages, protecting it from drying out. Eucalyptus essential oil has an analgesic effect.

Evkazoline suppresses the manifestation of tuberculous mycobacteria, the causative agent of trichomonas, staphylococcus and dysentery.

The effect of the drug occurs in the first minutes and lasts for ten hours. Considering that the drops are topical preparations, their absorption into the blood is not significant. They are not addictive. But they have contraindications, which limits their use to people at risk and pregnant women.

Use of the drug by pregnant women

Self-medication is especially dangerous in the first trimester, when the primary processes of the body are formed in the embryo. In subsequent periods there is no such strict restriction, but, nevertheless, is it possible to take Evkazolin during pregnancy, given that it is a vasoconstrictor drug.

The effects of the medicine can narrow not only the lumens of the vessels located in the nose, but also the capillaries of the placenta. This negative process is a direct road to hypoxia in the fetus.

The prescription of Evkazolin is determined by the need for its use and the impossibility of replacing it with more gentle means for the mother and unborn child. Therapy is carried out under the supervision of a doctor and in compliance with individual dosage.

Important. Treatment of runny nose in pregnant women should be carried out under the supervision of a doctor.

Indications for use

Therapeutic nasal drops Evkazolin for a runny nose are used to relieve symptoms of diseases that occur with severe swelling of the mucous membrane of the nasal passages and hypersecretion:

  • rhinitis;
  • sinusitis;
  • rhinosinusitis;
  • hay fever;
  • otitis media (elimination of swelling of the nasopharynx);
  • hay fever;
  • rhinitis and sinusitis of allergic origin.

The drug is also prescribed by the patient before diagnostics or therapeutic procedures of the nasal cavity.

Directions for use and overdose

Carefully. The use of Evkazolin drops for children under seven years of age is prohibited.

Before using the product, it is necessary to clean the nasal passages. Dosage for children aged 7 to 12 years, one drop in each nasal passage. The time interval between procedures is from 6 to 8 hours (2-3 times a day). The course of treatment depends on the clinical picture, on average lasting up to seven days.

Patients 12 years of age and above are prescribed two drops of the drug in each nasal cavity.

The frequency of the procedure is every 8-12 hours. The duration of the course is determined by the doctor and does not exceed ten days.

After treatment, if there is a need for re-administration, the drug Evkazolin is prescribed after seven days.

Long-term use of the drug and non-compliance with recommended dosages (overdose) can lead to:

  • to vision problems in the form of visual dysfunction, increased intraocular pressure;
  • hypertension;
  • frequent migraines;
  • drying out and atrophy of the mucous membrane of the nasopharynx;

If it is necessary to eliminate the consequences of an overdose, alpha-blockers are prescribed, the most commonly used of them is Phentolamine.

Contraindications and side effects

The use of Evkazoline cold drops is not indicated for people who:

  • allergic reaction to the constituent components of the drug;
  • hormonal activity of the thyroid gland (hyperthyroidism);
  • unstable intraocular pressure;
  • hypertension or tachycardia;
  • atrophied mucosal tissue in the nasal cavity;

Attention! The use of Evkazolin in children under seven years of age is strictly contraindicated.

The product belongs to the group of topical drugs, so there are not many side effects and they do not occur often. These include:

  • allergic reactions (frequent sneezing);
  • hypersecretion of mucus and liquefaction of the surface of the inner lining of the nose;
  • disorders of the cardiovascular system, increased blood pressure;
  • atrophy of the mucous membrane, a feeling of dryness in the nasal cavity;

Unsystematic, long-term use of the drug can lead to a weakening of the therapeutic effect and temporary deterioration or loss of olfactory receptors.

Conclusion

Like any drug, Evkazolin nasal drops should be taken after consultation with a doctor. Use drops with caution for people with diabetes mellitus, pathological changes in the functioning of the kidneys and adrenal glands. If carbohydrate metabolism is disturbed.

Evkazolin can change the psychomotor reaction, so you must be careful when using the drug when driving a car if your work activity is associated with mechanisms that require increased attention.

Directory of main ENT diseases and their treatment

All information on the site is for informational purposes only and does not claim to be absolutely accurate from a medical point of view. Treatment must be carried out by a qualified doctor. By self-medicating you can harm yourself!

Source: http://gorlonos.com/kapli/kak-primenyat-evkazolin.html

Evkazolin Aqua, Nasal Spray

Instructions for medical use

International nonproprietary name

Nasal spray 1 mg/g 10 g

One gram of spray contains

active substance: xylometazoline hydrochloride in terms of 100% substance 1 mg,

excipients: benzalkonium chloride, eucalyptus oil, disodium edetate, propylene glycol, macrogol 1500, povidone, hypromelose, polysorbate 20, sodium hydrogen phosphate dodecahydrate, potassium dihydrogen phosphate, water for injection.

When the drug leaves the bottle through a dispenser pump with a nasal spray, it is sprayed in the form of an aerosol stream, which has a specific odor and consists of liquid particles dispersed in the air

Medicines used for diseases of the nasal cavity. Sympathomimetics, simple drugs. Xylometazoline.

ATX code R01A A07

The drug has a predominantly local effect and is absorbed through the mucous membranes during normal use in small quantities. The effect of the drug begins in 5-10 minutes and lasts for 5-6 hours.

Evkazolin Aqua is a non-selective α-adrenergic agonist. When applied to the nasal mucosa, it has an anti-edematous effect, reduces hyperemia and exudation, which facilitates nasal breathing and reduces blood flow in the venous sinuses. Thanks to the presence of eucalyptus oil, it eliminates dry mucous membranes and exhibits anti-inflammatory and antiseptic effects.

Indications for use

  • symptomatic treatment of nasal congestion due to colds, hay fever, allergic rhinitis, sinusitis
  • auxiliary therapy for otitis media (to reduce swelling of the nasal mucosa)
  • during diagnostic interventions (rhinoscopy)

Directions for use and doses

For topical use. Immediately before use, you need to hold the bottle with the drug in your palm to warm it to body temperature.

Adults and children over 10 years old: 1 injection into each nasal passage 3-4 times a day.

The course of treatment depends on the course of the disease and should not exceed 7 days in a row.

After completing the course of treatment, the drug can be prescribed again only after a few days and after consultation with a doctor. The duration of treatment for children is determined by the doctor individually.

Possible side effects:

  • burning sensation in the nose or throat
  • tingling, dry nose
  • sneezing
  • nausea
  • dyspnea
  • angioedema

In isolated cases, systemic allergic reactions are possible.

With prolonged use or frequent use of high concentrations, the following may occur:

  • swelling of the nasal mucosa
  • manifestations of a resorptive effect in the form of dizziness, headache, insomnia, vomiting, increased blood pressure, palpitations, cardiac arrhythmias, short-term visual impairment

With especially prolonged use of the drug in high doses, a depressive state may develop.

Contraindications

  • hypersensitivity to any of the components of the drug
  • acute coronary diseases
  • coronary asthma
  • hyperthyroidism
  • angle-closure glaucoma
  • transsphenoidal hypophysectomy or a history of transnasal/transoral surgery exposing the dura mater
  • concomitant treatment with MAO inhibitors and for 2 weeks after stopping their use
  • pregnancy and lactation
  • children under 10 years of age

Evkazolin Aqua interacts with other drugs only if there is a resorptive effect. Adrenergic agonists from other groups enhance the effect of Evkazolin Aqua. Adrenolytics and sympatholytics, calcium antagonists weaken its effect.

Co-administration of monoamine oxidase inhibitors or tricyclic antidepressants may lead to an increase in blood pressure due to the effects of these drugs on the cardiovascular system.

The drug should not be used continuously for long periods (more than 10 days in a row) for chronic rhinitis. Long-term treatment with the drug may cause the opposite effect.

The recommended dose of the drug should not be exceeded, especially when treating children and the elderly.

The drug should be prescribed with caution to patients who experience strong reactions when using adrenergic drugs, manifested in the form of insomnia, dizziness, tremor, cardiac arrhythmia, and increased blood pressure.

The drug should be prescribed with caution to patients with cardiovascular diseases, arterial hypertension, patients with diabetes mellitus, thyroid diseases, and difficulty urinating.

Due to the vasoconstrictor effect of the drug, intraocular pressure may increase.

Each package of drops should only be used by one person to avoid infection.

Features of the effect of the drug on the ability to drive vehicles or operate other mechanisms.

The drug does not affect the ability to drive vehicles and operate complex machinery when used in recommended doses, but the likelihood of temporary visual impairment should be taken into account.

Symptoms: headache, dry nose, nausea, depression, increased blood pressure, short-term blurred vision.

Treatment: it is necessary to stop using the drug and use antagonist drugs: sympatholytics and α-blockers (phentolamine, tropafen), symptomatic therapy.

If you accidentally drink the drug, you need to rinse your stomach, take laxatives and enterosorbents. Treatment with α-blockers is indicated; symptomatic therapy.

Release form and packaging

10 g in a brown glass bottle, equipped with a dispenser pump with a nasal spray. A self-adhesive label is placed on the bottle. Each bottle, along with instructions for medical use in the state and Russian languages, is placed in a cardboard pack.

Store in a place protected from light, at a temperature not exceeding 25 ºС.

Keep out of the reach of children!

Do not use the drug after the expiration date indicated on the package.

Conditions for dispensing from pharmacies

PJSC “Farmak”, Ukraine, 04080, Kyiv, st. Frunze, 63.

Registration Certificate Holder

Address of the organization that accepts claims from consumers regarding the quality of products (products) on the territory of the Republic of Kazakhstan

Republic of Kazakhstan, Almaty, Abay Ave. 157, office 5

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