For children Ingaron

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Ingaron for children: instructions for use

During the season of viral infections, mothers are especially actively interested in drugs that can stimulate the immune system. One such remedy is Ingaron. Is it allowed for children, when is it prescribed and how is it used correctly in childhood?

Table of contents:

Release form

Ingaron is produced in glass bottles, inside of which there is a lyophilisate. It is represented by a white hygroscopic mass, which can be porous or loose. One pack of medicine is a cardboard box, inside of which there are 1 or 5 contour packages. Each such package includes a bottle with lyophilisate and an ampoule with a solvent, as well as a medical pipette or dropper cap.

The drug is also available in injection form, which differs only in a higher concentration of the active component. One package can contain from 1 to 20 bottles of medicine.

Compound

The effect of the drug Ingaron is provided by human interferon of the gamma type. One bottle for use in the nose contains ME of this substance. The injection form of Ingaron contains interferon in a dose of 100 thousand IU, 500 thousand IU, as well as 1 million IU or 2 million IU. The only auxiliary component of the medicine is mannitol. The ampoule included in the package contains 5 ml of water for injection.

Operating principle

Ingaron is an immunostimulating drug, since gamma interferon in its composition has the following effect on the immune system:

  • Activates the function of immune cells (neutrophils, natural killer cells, macrophages, T-lymphocytes with cytotoxic effects) by binding to their receptors. As a result, they more actively produce cytokines and other substances that have antiviral and anti-inflammatory effects.
  • Blocks the formation of RNA or DNA of viral cells, as well as the synthesis of viral proteins, which disrupts the replication of viral particles.
  • It has a toxic effect on virus-infected cells.
  • Inhibits the response of B cells to interleukin 4, and also reduces the production of immunoglobulin E.
  • Activates the destruction of those B cells that provoke the development of autoimmune reactions.
  • Supports the production of proteins involved in suppressing the inflammatory response and also affects the complement system.
  • Prevents the formation of substances that provoke fibrotic changes in the liver or lungs.

Indications

Most often, Ingaron in intranasal form is prescribed to children for the treatment of influenza, especially when infected with such dangerous strains as H1N1 or H5N1. In addition, the drug can be used to prevent this viral infection, as well as in the treatment of other acute respiratory viral infections.

Ingaron injections are prescribed for viral hepatitis, tuberculosis, herpes zoster, cancer pathologies, HIV infection, genital herpes, chlamydia and other diseases.

At what age is it allowed to take it?

According to the instructions, the use of Ingaron for children under 7 years of age is not recommended. If the child is younger, in his treatment or for preventive purposes it is better to use other immunostimulating drugs that are suitable for his age. This is due to the lack of clinical trials of the lyophilisate and the characteristics of the immune system in childhood (while it is just being formed, any immune drugs are undesirable).

Contraindications

In addition to age restrictions, Ingaron administered nasally has only one more contraindication - the drug is not given if there is an individual intolerance to it. Adults do not use the medicine while pregnant, and the injection form cannot be used for diabetes and autoimmune pathologies.

Side effects and overdose

Nothing is known about cases of side effects of the drug on the body of patients or an overdose of Ingaron in the form of nasal drops. Injections may cause soreness or redness at the injection site. If very high doses are used, the patient may experience weakness, fever, and pain in the head and joints.

Instructions for use and dosage

The medication is used intranasally. Before starting treatment, it is necessary to properly prepare the solution.

  1. Gently pry the bottle cap, made of plastic, with your finger, without tearing it off completely.
  2. Moving in a circle, remove this cap along with the metal cap.
  3. After removing the rubber cap and opening the ampoule with sterile water, add it to the bottle.
  4. Place the dropper cap on the bottle and shake the solution.
  5. Apply drops to the child's nose and place the drug in the refrigerator until next use.

It is recommended to start using Ingaron at the first symptoms of flu. After clearing the little patient’s nasal passages of crusts or secretions, 2 drops of the solution are injected into each nostril of the child. The product should be instilled 5 times a day, and the duration of treatment is usually 5-7 days. As soon as the medication has entered the nasal cavity, you need to massage the wings of the nose for several minutes so that the solution is distributed evenly throughout the mucous membrane.

Ingaron is used prophylactically after contact with a patient or after hypothermia. The course of prophylactic administration lasts 10 days and involves instilling the medicine every other day into each nostril, 2 or 3 drops. If a child has interacted with someone who has the flu, then prophylaxis can be done once, by instilling the drug only once after such contact.

Sometimes doctors prescribe inhalations with Ingaron. For one procedure using a nebulizer, use one bottle of medication and 2 ml of water for injection.

Ingaron injections are given subcutaneously or intramuscularly after diluting the bottle with 2 ml of water for injection. The dosage is determined in each case individually, and the duration of treatment can be up to 3 months.

Interaction with other drugs

Ingaron is allowed to be combined with any other medications prescribed for ARVI or influenza, for example, with antipyretics.

Terms of sale and storage

To purchase the intranasal form of Ingaron at a pharmacy, you do not need to obtain a prescription from a doctor, however, when used in children, a doctor’s consultation is advisable. The injection form of the drug is a product that is sold by prescription. The average price of a package with one bottle of lyophilisate is rubles.

The shelf life of the medicine is 2 years. Until it expires, you can keep sealed contour packages of Ingaron at home for administration into the nose at room temperature (not higher than +25 degrees) in a dark place where a small child cannot reach.

After diluting the lyophilisate, the medication should be placed in the refrigerator, but it should not be frozen. The solution can be stored for up to ten days. The injectable form of the medicine should always be stored in the refrigerator.

Reviews

The use of Ingaron in children for the prevention of viral diseases or the treatment of influenza is generally well received. Mothers confirm that the course of treatment helped the child not get sick during the cold season or suffer from the flu without complications. The disadvantages of the drug include age restrictions, short shelf life and high price. Also, in some children, treatment with Ingaron did not give the expected improvement.

Analogs

Other drugs that contain interferon can replace Ingaron. They have a similar effect on the child’s body, although they include not gamma, but alpha interferons.

Instead of lyophilisate, your doctor may recommend:

  • Infagel. This medicine in gel form can be used to prevent ARVI or influenza in children of any age. To do this, lubricate the mucous membrane of the nasal passages with the drug for a week. The medicine is also effective when infected with herpes, for example, with chickenpox rashes or herpes blisters on the lip.
  • Grippferon. This medicine, available in drops and spray, is often prescribed for viral infections of the respiratory system. Even infants are allowed to drip it.
  • Genferon Light. The composition of this medication includes a combination of interferon and taurine. The drug is produced in drops and suppositories, which are allowed at any age.
  • Viferon. This interferon drug is used in children for chickenpox, ARVI, candidiasis and other diseases. In the form of gel and rectal suppositories, it is allowed from birth, and ointment is used in babies older than one year.

A few words from Dr. Komarovsky about immunomodulators in the next video.

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Antiviral nasal drops Ingaron

Ingaron is an antiviral drug whose active ingredient is interferon-gamma. Gamma interferons are the only way to stimulate cellular immunity and activate the body’s most important defense mechanisms.

Ingaron makes the body's cells immune to virus invasion. It has proven its effectiveness at different stages of the infectious process, ensuring rapid recovery both in the first moments of the disease and at the peak of the disease, even with pneumonia.

About the drug

Ingaron gained particular popularity after 2009, when the swine flu pandemic broke out, which, according to official data, killed more than 300 thousand people across the planet. The drug was created specifically for high protection of the population from an influenza pandemic.

It quickly stops coughing, reduces the likelihood of otitis media, shortens the duration of the disease and relieves its severity, but most importantly, the drug protects against the development of a serious influenza complication - pneumonia.

The body's production of interferons is the first defense of cells against viruses, which appear much earlier than antibodies and other protective immunity factors. Interferon gamma also stimulates the human immune system, activating cells that destroy viruses.

Interferon-gamma is the most important anti-inflammatory substance in the human body, capable of blocking the virus and human cells into which the virus has managed to penetrate at the DNA level. It makes healthy human cells immune to viruses. The duration of action of the drug is sufficient to protect the body and provide a therapeutic effect.

Ingaron is the only cytokine protein that significantly reduces the risk of allergic reactions and goes well with antibiotics and drugs for symptomatic treatment (Paracetamol, Ibufen, cough and sore throat remedies).

Release form and manufacturer

Ingaron is produced by the Russian company Pharmaklon. This is a white, loose powder that must be diluted with water for injection. Available in poiME bottles, 1 or 5 bottles in a cardboard package. Water for injection and pipette included.

Storage conditions

Store at a temperature of +2–8 degrees out of the reach of children. The prepared solution can be stored for 10 days in the refrigerator. Freezing ampoules with powder and the finished solution is prohibited. Do not use the drug after the expiration date!

Indications

  1. Treatment and prevention of respiratory viral infection.
  2. Prevention and treatment of seasonal influenza as part of complex therapy.
  3. Prevention and comprehensive treatment of swine flu (H1N1) and H5N1 influenza. Ingaron is the only patented highly effective remedy to combat the avian influenza virus.

The Influenza Institute recommends the use of Ingaron nasal drops for prevention when visiting public transport, schools, theaters and cinemas, work offices and other places with large crowds of people, as well as during trips to areas unfavorable for morbidity.

The use of Ingaron during an outbreak, regardless of the pathogen, will help prevent the development of the disease and speed up the recovery process.

This is interesting

The uniqueness of the Russian drug Ingaron has been proven by the Influenza Research Institute of the Russian Academy of Medical Sciences. It has passed all stages of clinical trials for indications for use in the treatment of cancer, infectious and viral diseases. Based on the data obtained, standards for the treatment of influenza, cervical cancer, breast cancer, tuberculosis, hepatitis, and AIDS were developed and approved.

No adverse reactions were reported when using Ingaron nasal drops. But if flu-like symptoms appear after using the drug, you must take any remedy that relieves these symptoms - Paracetamol, Ibufen.

Contraindications

The official instructions for use indicate that Ingaron in the form of nasal drops is contraindicated in the following situations:

  1. In case of individual intolerance to mannitol or interferon-gamma;
  2. During pregnancy and breastfeeding;
  3. In the presence of autoimmune diseases;
  4. Children under 7 years of age.

Before using the drug, carefully read the instructions for use. Women of childbearing age should not plan pregnancy while taking Ingaron; it is recommended to use contraception. If pregnancy occurs, you need to stop the drug and consult a doctor.

Mode of application

Before starting treatment, you should consult your doctor and read the instructions, be careful when diluting, storing and using the drug.

  1. Open the ampoule with powder (the contents of the ME ampoule are calculated for 5 ml of water for injection).
  2. Add the contents from the ampoule with injection water to it.
  3. Close the bottle with a stopper.
  4. Shake the contents until completely dissolved.
  5. Place into the nose with the pipette supplied with the drug by the manufacturer.

If symptoms of flu or cold appear, apply 2 drops into the nose 5 times a day for a week. First, you need to rinse your nose and blow your nose well; after instillation, massage the wings of the nose thoroughly for 1–2 minutes so that the drug spreads evenly and does not leak out into the throat.

If a person has become hypothermic or has interacted with a sick person, then as a preventive measure for flu and colds, you need to drop 2-3 drops into the nose in the morning half an hour before meals for 10 days. If there is a repeated need for prophylaxis, the drug can be used again and again. For a single contact with a sick person, a single use of Ingaron in the amount of 3 drops is sufficient for prevention.

It is forbidden to use the drug more than a single or daily dose; increased dosages increase the risk of side effects.

If one dose is missed

If an appointment was missed, you need to resume the course of treatment as soon as possible. Continue as usual. Taking a double dose is prohibited.

Analogs

Analogues are those medications that can replace Ingaron. Ingaron has no structural analogues of the active substance (interferon-gamma), but interferon inducers, umifenovirs and drugs containing interferon-alpha are widely used as antiviral agents, along with interferon-gamma:

  • Grippferon (nasal drops);
  • Viferon:
  • Human leukocyte interleukin (solution dripped into the nose);
  • Amiksin:
  • Cycloferon;
  • Alfaron (nasal drops);
  • Anaferon, etc.

The cost of the drug varies depending on the region of the country and pharmacy.

  • The average price for 1 bottle of ME is 300 rubles.
  • Average price for 5 bottles of ME – rub.
  • Average price for 1 bottle of ME – rub.
  • Average price for 5 bottles of ME – rub.

Drug interactions

The drug is well tolerated and combines well with other drugs for the treatment of flu and colds. However, undesirable effects may occur if a person simultaneously takes antithymocyte globulin, strontium-89 chloride, theophylline, and drugs for the treatment of cancer. In any case, you need to inform your doctor about all the medications you are taking at the time of treatment.

Reviews on the Internet

Internet users leave only positive comments. People tested interferon-gamma on themselves and were convinced that the drug helps avoid frequent colds and flu.

In a healthy and strong, hardened body, an infection is unlikely to cause illness, but with reduced immunity, viruses lead to illness and its complications. Therefore, the drug is recommended for those who suffer from colds every month.

Ingaron can really save you from the development of colds and flu, reduces the risk of complications, the duration and severity of the disease. Protect yourself and your loved ones from flu and colds.

The information provided can be used for informational purposes, as it is a simplified and short version of the official instructions for use.

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Ingaron - instructions for use, reviews, analogs and release forms (powder for preparing a solution in the nose, drops or spray, injections in injection ampoules) of a drug for the treatment of hepatitis, herpes, leprosy in adults, children and pregnancy. Compound

In this article you can read the instructions for use of the drug Ingaron. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Ingaron in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Ingaron analogues in the presence of existing structural analogues. Use for the treatment of hepatitis, tuberculosis, psoriasis, leprosy in adults, children, as well as during pregnancy and lactation. Composition of the drug.

Ingaron is a glycoprotein with a molecular weight of μDa and is known as immune interferon. Derived from stimulated human T lymphocytes. Currently, recombinant DNA techniques using bacterial cells are increasingly being used to obtain interferon gamma. There are two known types of interferon gamma - gamma 1a and gamma 2a, differing in the sequence of amino acids in their chain at positions 1 and 139. It has a pronounced immunomodulatory activity, as it enhances the expression of major histocompatibility complex antigens of classes 1 and 2; activates macrophages, enhances the activity of natural killer cells; reduces the expression of a subset of B cells, monocytes and eosinophils induced by IL-4; and also reduces the production of IgE; stimulates the growth and differentiation of B cells.

Interferon gamma + excipients.

  • treatment of chronic viral hepatitis C, chronic viral hepatitis B, HIV/AIDS infection and pulmonary tuberculosis in complex therapy;
  • prevention of infectious complications in patients with chronic granulomatous disease;
  • treatment of oncological diseases in complex therapy as an immunomodulator, incl. in combination with chemotherapy;
  • treatment of genital herpes virus infection and herpes zoster (Herpes zoster) in monotherapy;
  • treatment of urogenital chlamydia in complex therapy;
  • treatment of chronic prostatitis in complex therapy;
  • treatment of anogenital warts (human papillomavirus) and prevention of relapse of the disease;
  • psoriasis;
  • as maintenance therapy for cutaneous and visceral leishmaniasis;
  • mycobacterial infection in HIV-negative patients with ineffective conservative therapy;
  • leprosy;
  • prevention of influenza and ARVI;
  • as an alternative therapy for rheumatoid arthritis;
  • eczema and atopic dermatitis, especially with high IgE levels;
  • as an additional agent to antibiotic therapy for lymphogranulomatosis.

Lyophilisate or powder for preparing a solution for intranasal administration of ME (sometimes mistakenly called nasal drops or spray).

Lyophilisate or powder for the preparation of a solution for intramuscular and subcutaneous administration of ME, ME, ME and ME (injections in ampoules for injection).

Instructions for use and dosage regimen

Intranasally. The contents of the bottle are dissolved in 5 ml of water for injection.

2 drops in each nasal passage after toileting the nasal passages 5 times a day for a day.

For the prevention of acute respiratory viral infections and influenza upon contact with a patient and/or hypothermia, drops into each nasal passage every other day for 10 days. If necessary, preventive courses are repeated. For single contact, one instillation is sufficient.

After instillation, it is recommended to massage the wings of the nose with your fingers for several minutes to evenly distribute the drug in the nasal cavity.

Ampoules for injections

The drug is administered intramuscularly or subcutaneously. The contents of the bottle are dissolved in 2 ml of water for injection. The dose of the drug is determined individually.

For the treatment of patients with chronic viral hepatitis B, chronic viral hepatitis C, as well as HIV/AIDS infection and pulmonary tuberculosis, the average daily dose for adults is ME. The drug is administered once a day, daily or every other day. The course of treatment ranges from 1 to 3 months, if necessary, the course of treatment is repeated after 1-2 months.

For the prevention of infectious complications in patients with chronic granulomatous disease, the usual average daily dose for adults is ME. The drug is administered once a day, daily or every other day. The course of treatment is injections; if necessary, the course is extended or repeated every other day.

For the treatment of cancer, the average daily dose for adults is ME. The drug is administered once a day, every other day.

For the treatment of genital herpes virus infection, herpes zoster and urogenital chlamydia, the average daily dose for adults is IU. The drug is administered once a day, subcutaneously, every other day. The course of treatment is 5 injections.

For the treatment of chronic prostatitis, the daily dose is ME. The drug is administered once a day, subcutaneously, every other day. The course of treatment is 10 injections.

For the treatment of anogenital warts, the daily dose is ME. The drug is administered once a day, subcutaneously, after cryodestruction, every other day. The course of treatment is 5 injections.

  • local soreness at the site of subcutaneous injection in the form of mild aching pain (like an overtrained muscle) and hyperemia;
  • development of influenza-like syndrome: headache, weakness, fever, joint pain. Mild symptoms do not require pharmacological correction. In case of severe symptoms, relief with paracetamol.
  • pregnancy;
  • autoimmune diseases;
  • diabetes;
  • children under 7 years of age (for intranasal use);
  • individual intolerance to interferon gamma or any other component of the drug.

Use during pregnancy and breastfeeding

Ingaron is contraindicated during pregnancy.

The intranasal form of the drug is contraindicated in children under 7 years of age.

In case of pronounced local and general reactions, treatment should be stopped; in case of severe side effects, corticosteroids should be used to relieve them.

In the Russian Federation, at the time of publication of the drug in the Directory, the nasal form of Ingaron was not registered.

No drug interaction data provided.

Analogues of the drug Ingaron

The drug Ingaron has no structural analogues for the active substance.

Analogs by pharmacological group (interferons):

  • Avonex;
  • Algeron;
  • Altevir;
  • Alfarona;
  • Alfaferon;
  • Betaferon;
  • Vagiferon;
  • Viferon;
  • Wellferon;
  • Genfaxon;
  • Genferon;
  • Genferon Light;
  • Herpferon;
  • Giaferon;
  • Grippferon;
  • Interal;
  • Interferal;
  • Interferon alpha human recombinant;
  • Interferon beta human recombinant;
  • Interferon gamma human recombinant;
  • Human leukocyte interferon;
  • Human leukocyte interferon in suppositories;
  • Interferon alpha recombinant ointment on a hydrogel basis;
  • Intron A;
  • Infagel;
  • Inferon;
  • Infibeta;
  • Kipferon;
  • Laifferon;
  • Lokferon;
  • Oftalmoferon;
  • PegAltevir;
  • Pegasis;
  • Peginterferon;
  • Realdiron;
  • Reaferon EU;
  • Reaferon EC Lipint;
  • Rebif;
  • Ronbetal;
  • Roferon A;
  • SinnoVex;
  • Extavia.

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Indications for taking Ingaron for adults and children - release form, composition, side effects and analogues

To restore immunity and fight viruses, special types of medications are often used. These include Ingaron - instructions for use, which describe in detail the treatment with the drug, the duration of the course of therapy and other nuances. Below is information about indications for use, dosage, contraindications and cost of the product.

What is Ingaron

When cold weather sets in, viral infections often affect children and adults. To reduce the risk of the disease or to cope with it faster, doctors recommend using interferon drugs. They have a high level of biological activity, due to which they effectively fight harmful microorganisms. These medications include Ingaron, a recombinant drug that contains human interferon gamma, which combines immunomodulatory and antiviral effects.

The drug Ingaron is capable of destroying many different viruses. The active substance of the drug prevents them from attaching and introducing themselves into the body; it eliminates cells that have already been infected by the virus. The medicine with interferon gamma has a lot of positive qualities:

  • complete exclusion of infection from entering the human body;
  • viruses cannot adapt to Ingaron;
  • the medicine has practically no toxins in its composition, therefore it is taken in large doses without risk to health;
  • Ingaron is able to directly act on parasitic organisms throughout the entire period of illness;
  • Interferon has the ability to accumulate in the human body, so the immune system is significantly strengthened.

Composition and release form

The antiviral and immunomodulatory drug Ingaron is produced in the form of a powder - lyophilisate. A loose or porous substance is used to prepare the solution. The powder is available in two forms: for injection and intranasal use. You can purchase the product at a regular pharmacy kiosk or buy it in an online store. It is easily recognized by its hermetically sealed glass bottles with a volume of 3 and 5 ml. The number of bottles varies (1.5, 10 or 20 pieces), they are placed in a cardboard package.

The main active substance of Ingaron is gamma interferon - this is a type of protein consisting of many amino acids. It is obtained by microbiological synthesis in a strain of Escherichia coli, and then purified as much as possible by column chromatography. The interferon content in the drug is measured in international units (IU). One bottle may contain, or ME. In addition to the main active component, Ingaron contains an additional element - mannitol.

Mechanism of action

As mentioned earlier, Ingaron is a medicine with a strong antiviral effect on the body. It restores and strengthens the immune system. When the active substance of the drug enters the blood, cellular phagocytosis is “turned on,” which catalyzes the natural defense mechanism of the immune system and blocks the development of viral cells.

Indications for use

To get the desired result from taking the medication, you need to carefully study the instructions for its use. Ingaron in the nose or for injection is prescribed in the following cases:

  1. Complex treatment of pulmonary tuberculosis.
  2. Viral hepatitis B, C.
  3. Herpes and genital herpes.
  4. Complex therapy for HIV and AIDS includes the use of Ingaron.
  5. Restoring the body after a course of chemotherapy or radiation treatments, maintaining immunity after prolonged treatment with antibiotics or cytostatics.
  6. Therapeutic measures aimed at combating chlamydia.
  7. Chronic inflammation of the prostate in men is also treated with Ingaron.
  8. In some cases, interferon is also used to eliminate the papilloma virus that has affected the genitals.

Instructions for use of Ingaron

Before starting treatment with Ingaron, you should definitely consult with a specialist and take into account all the features of administration specified in the instructions for use. The powder is diluted in a certain proportion, and then injections are made or the resulting liquid is instilled into the nose. It is worth remembering that the lyophilisate for intranasal and injection use differs in the manufacturing method. This means that injection medicine cannot be used as drops and vice versa.

Parenterally

To prepare a solution for injections, in addition to Ingaron, purified water or saline solution is useful. Take 2 ml of liquid and dissolve the medicine from one bottle in it. You should get a transparent, homogeneous mixture without sediment. An intramuscular or intravenous injection is given with Ingaron. The dosage of the drug depends on the specific disease, patient characteristics and other factors. Often, medication doses are distributed as follows:

  1. For the treatment of HIV infection, hepatitis, AIDS, and respiratory tract tuberculosis, the approximate daily dose is 500 thousand IU. Ingaron must be injected once every 24 hours every day (or every other day). The course of treatment is from 1 to 3 months.
  2. Oncological diseases require one-time injections every other day. The duration of therapy is determined by the doctor.
  3. To prevent the occurrence of infectious consequences after granulomatosis, IngaronME is used. The drug is administered once every two days or daily. The course of treatment consists of 5-15 injections.
  4. Acute or chronic inflammation of the prostate gland (prostatitis) is also often healed with Ingaron solution. It is administered with PME every day. One bottle is used per day, the duration of therapy is 10 days.
  5. Herpes infection (including chronic) or the diseases that it provokes are treated with Ingaron according to strict instructions. Five bottles of 500 thousand units of interferon will be required for daily subcutaneous injection. If necessary, treatment is repeated.
  6. Therapy with Ingaron, aimed at eliminating anogenital warts, allows the use of ME per day. You can administer the drug 5 days in a row or once every two days.

As a nasal spray

For intranasal use of Ingaron, powder - lyophilisate is diluted with 5 ml of liquid (saline, distilled water). Immediately after the procedure, it is recommended to do a light massage of the nasal wings. Ingaron drops are used according to the following scheme:

  1. When treating acute respiratory infections, ARVI, and influenza at the initial stage, 2 drops in each nostril 5 times a day are enough. The duration of the treatment course is a week.
  2. When there is a one-time contact with a person who is a carrier of the influenza virus, then only a one-time instillation is done.
  3. To prevent viral infections, doctors advise taking 3 drops of Ingaron every other day, 30 minutes before eating. Duration of therapy – 10 days.

Side effects

Sometimes, after using Ingaron, side effects are recorded (they may be absent). The most common manifestations are:

  • feeling of body aches;
  • headache, weakness;
  • temperature increase;
  • itching, burning in the nostrils after the instillation procedure;
  • the formation of an inflammatory process in the area of ​​the body where Ingaron was injected (this is often caused by a needle getting into a nerve or vessel);
  • pain in the joints;
  • skin allergies (there are contour rashes if the patient is intolerant to the medication).

Contraindications

Before using Ingaron powder for injection or intranasal use, be sure to read the instructions. Among other things, it specifies restrictions on interferon treatment. Contraindications:

  • diabetes;
  • pregnancy;
  • age category up to 7 years;
  • personal intolerance to the constituent elements of the drug;
  • autoimmune diseases.

Interaction with other drugs

To avoid complications when using Ingaron, doctors advise not only to read the instructions well, but also not to use certain forms of drugs simultaneously with interferon. Considering the fact that Ingaron supplements the action of antibiotics, antiviral drugs, and immunomodulators, it is advisable not to abuse it. In any case, a specialist should monitor the treatment process and its results.

Ingaron's analogues

If the components of Ingaron are not suitable for a particular patient, then the doctor prescribes an analogue of this drug:

  • Lipoferon (treats hepatitis B);
  • Afonex (various bacterial, viral infections);
  • Virogel (herpes, ARVI, influenza);
  • Genferon (flu, acute respiratory infections, ARVI);
  • Viferon (modern antiviral agent);
  • Alfaron (strengthens the immune system in case of cancer);
  • Alpha insone (hepatitis C);
  • Laferobion (prevention, therapy of viral infections);
  • Pegintron (hepatitis B).

As a rule, the cost of the immunostimulant and antiviral drug Ingaron depends on the specific pharmacy and the number of bottles in the package. The drug can also be purchased in an online store at a more affordable price (if you order through a virtual catalog, there are often discounts and promotions). Below is a table showing the approximate average cost of Ingaron in Moscow and the region.

Name of the drug

Number of bottles and interferon (IU) content

Average price in rubles

Ingaron for injections

5 bottles of 500 thousand units each

Ingaron for injection

5 bottles of 100 thousand units

Powder for injections

1 bottle naME

Ingaron for intranasal use

1 bottle of units

Means for making nasal drops

5 bottles of PME

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Video

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and make recommendations for treatment based on the individual characteristics of a particular patient.

Source: http://sovets.net/12171-ingaron-instrukciya-po-primeneniyu.html

Ingaron in the form of nasal drops and solution for injection: instructions for use

Latin name: INGARON

Active ingredient: Interferon gamma

Manufacturer: TOV NPP “Farmaklon”, Russia

Condition for dispensing from the pharmacy: Without a prescription

Compound

One bottle contains: interferon gamma 100 thousand IU, 500 thousand IU, 1 million IU and 2 million IU. Additional substance: mannitol.

Medicinal properties

Ingaron is a medicinal substance with antiviral, immunostimulating and immunomodulating effects on the human body. The composition includes human gamma-type interferon, which is the main antiphlogistic cytokine involved in the development of immunity. It stimulates the performance of effector functions at the cellular level, which in turn leads to the death of parasites inside the cells and has a detrimental effect on virus-infected cells. Interferon gamma, which is part of Ingaron, inhibits the synthesis of beta-TGF, which is responsible for the ontogenesis of fibrosis of lung and liver tissues. It activates protein synthesis, which is characteristic of an acute inflammatory process, and it also stimulates the process of converting DNA into RNA and protein.

Indications for use

Ingaron is used as an immunomodulator, correcting problems of cellular immunity, as a therapeutic treatment for infectious diseases, influenza, allergies, oncology and autoimmune disorders.

Ingaron is used as an injection solution. It is used as intramuscular and subcutaneous injections. Recommended additional treatment if:
  • Tuberculosis of the respiratory system, hepatitis, HIV, AIDS
  • Oncology (and also as an immunomodulator during chemotherapy)
  • Urogenital infection, in particular chlamydia
  • Chronic prostatitis
  • Anogenital warts, also to prevent the return of the disease.

In addition, interferon gamma is prescribed:

  • For granutematosis in the form of prevention of infections
  • As a monotherapy for herpes zoster and herpes virus infections. (For more information about herpes, see the article: Rash on the lips).

Use of Ingaron intranasally (in the form of drops):

  • As group therapy for acute respiratory viral infections, acute respiratory infections, influenza, and prevention of colds in winter, as well as seasonal “bird” flu
  • As a maintenance treatment of skin diseases: psoriasis, eczema, atopic dermatitis, leprosy, cutaneous or visceral leishmaniasis
  • As an alternative drug course of therapy for rheumatoid arthritis
  • During the course of lymphogranulomatosis, in complex antibacterial therapy.

Release forms

The average price for 1 piece is 350 rubles

Inragon has the appearance of a porous, loose powder, white. It is used in the manufacture of injection solution. Produced in glass bottles, packed in cardboard boxes with a capacity of 1, 5, 10 or 20 pieces, containing the main component interferon gamma in quantity, units, 1 million units. and 2 million units.

Ingaron powder is also used to make a nasal solution. Available in glass bottles of 1 or 5 pieces. in a package containing the main medicinal substance interferon gammaed.

Mode of application

Use of the drug parenterally

The drug Ingaron is used as an injection solution for injection under the skin or intramuscularly. When preparing a parenteral mixture, saline is required. solution or distilled water. So, add Ingaron from a bottle to 2 ml of liquid for injection; as a result, the resulting mixture should be without sediment, transparent and homogeneous, only in this case it is ready for use.

The storage time of the prepared solution is no more than three minutes.

The exact dosage of Ingaron is determined by the doctor.

For therapeutic purposes for hepatitis and HIV infections, AIDS, respiratory tract tuberculosis - the average daily norm for adults is 500 thousand IU. Take Ingaron every day, or every other day, once every day, for 1-3 months. At the end of treatment, a break of up to 2 months is taken, then treatment can be carried out again.

In order to prevent the occurrence of complications in the form of infections in granulomatosis, the average daily norm is 500 thousand IU. Ingaron, taken every day or once every two days. The entire course of drug therapy is 5-15 injections. Treatment can be extended or repeated after 2 weeks if necessary.

For oncological diseases in adults, the average daily dose of a drug containing gamma interferon is 500 thousand IU. The medicine is taken once a day, every other day.

When diagnosing diseases caused by herpes viral infection types 2-3, a course of drug treatment is carried out with an average daily dose of Ingaron - 500 thousand IU. Interferon gamma is administered to the patient subcutaneously, 1 time per day. The treatment consists of five injections administered to the patient every other day.

Prostatitis is treated with injections administered under the skin in a dose of funds per day. The solution is taken once a day for 10 days, or alternatively every other day for 20 days. The course of treatment should not exceed 10 injections.

Anogenital warts are treated with medication. medications per day by subcutaneous injection. The drug is prescribed after cryodestruction, lasting up to five injections, an injection every day, or once every two days.

Using the drug as a nasal spray

To use the drug Ingaron in the form of nasal drops, the powder is diluted in saline. solution or in distilled water with a volume of 5 ml.

At the initial manifestations of influenza, ARVI or acute respiratory infections, drop 2 drops of the product into each nasal passage. Ingaron is used 5 times a day for 5-7 days, both for the treatment of adults and children.

As a preventive measure against acute respiratory viral infections, acute respiratory infections, influenza, after contact with patients, in case of hypothermia, instill 2-3 drops of the drug into the nose, half an hour before breakfast, every other day. Course 10 days. According to indications, the preventive course of treatment can be repeated.

If there was a one-time contact with someone with the flu, then a one-time use of the product will be sufficient.

Upon completion of instillation of drops, it is necessary to massage the wings of the nose for two to three minutes.

Contraindications

Drug therapy with Ingaron is contraindicated in patients of the following categories:

  • With intolerance to the components of the drug
  • Children under 7 years old
  • During pregnancy
  • With autoimmune problems (with intramuscular and subcutaneous use)
  • For diabetes mellitus (with intramuscular and subcutaneous use)
  • Use caution in case of severe allergic reactions.

During pregnancy and breastfeeding

The use of Ingaron during pregnancy of any stage is contraindicated. During lactation, the effect of the drug has not been studied.

Drug interactions

No special manifestations.

Side effects

Painful sensations such as aching pain are of weak etiology; a local inflammatory process is also possible. Side effects are not a reason to stop treatment.

When taking higher doses (more than one unit), chills and elevated body temperature may occur, lethargy, joint pain and headaches are also observed, conditions similar in description to the flu. Minor manifestations of side effects do not require drug treatment; with obvious symptoms, take paracetamol tablets. Another side symptom may be the appearance of itching and rashes on the skin.

Overdose

If the permissible daily dose of Ingaron is exceeded, more than one unit. may lead to the development of flu-like symptoms. In this case, it is recommended to take paracetamol tablets in therapeutic doses.

Conditions and shelf life

Storage of the medicinal product should not exceed more than 2 years from the date of manufacture. After preparation, the solution is used immediately; it cannot be stored. Should be kept out of direct sunlight and out of the reach of children. The drug in an unopened bottle is stored in the refrigerator at a temperature of 2 to 10 degrees Celsius. Don't freeze.

Analogs

VIFERON

FERON LLC, Russia

Price from 160 rub. up to 868 rub.

Active ingredient: Human recombinant Interferon alpha-2b, excipients: ascorbic acid, tocopherol acetate. Viferon ointment is available in a jar or tube, containing 400 thousand units of active ingredient. Rectal suppositories (containing the active substance: units, units, units, units) are produced in 10 pcs. packaged.

  • Candles can be used by both premature and full-term babies
  • Possibility of use by pregnant women (from 14 weeks), nursing
  • Viferon can be combined with any medications.
  • Allergies, skin rashes and itching may occur.

Source: http://lekhar.ru/lekarstva/protivomikrobnye-preparaty/ingaron-instrukcija-po-primeneniju/

Ingaron drops - instructions for use, analogues, reviews

ARVI and influenza annually affect large sections of the population, resulting in epidemics. The weakened immunity of citizens often cannot resist the attack of viruses, and the disease takes over. It is no secret that prevention is the gold standard of treatment, and it is foolish to skimp on it.

Some people are skeptical about prophylactic drops, tablets, and injections. But there are also people who like to get vaccinated against all infections, and also take everything they can to avoid getting the flu.

One of the Russian-made drugs that prevents influenza, ARVI and other infections is ingaron (nasal drops). It is the nasal form of the drug that is used for the prevention and successful treatment of respiratory diseases.

Advantages of Ingaron

The drug is aimed at stimulating the cellular immunity, due to which all the body’s defense mechanisms are concentrated and activated.

Ingaron drops help cells ignore viruses, i.e. do not perceive the attack of viral agents. This feature of the drug allows not only to prevent the disease, but also to speed up recovery if it occurs.

Ingaron drops showed excellent therapeutic results during the swine flu pandemic. Therefore, not only clinical trials, but also the practical use of ingaron have proven the decent effectiveness of this drug. This is truly an anti-pandemic remedy.

According to research, with the prophylactic intranasal use of ingaron, influenza and ARVI can be prevented in 90% of all cases.

While taking the drug, there is a decrease in all flu symptoms: the symptoms of general intoxication are eliminated, coughing, aches in muscles and joints are stopped, and most importantly, the spread of infection is quickly inhibited. Ingaron prevents the flu from developing complications, especially such serious ones as pneumonia.

Ingaron consists of interferon-gamma, which has powerful anti-inflammatory, antiviral and immunomodulating effects. This combination quickly eliminates the symptoms of the disease, reducing its duration. The medicine is combined with many drugs and does not cause side effects or addiction.

In order to learn more about how to use ingaronME (nasal drops), let's briefly look at its instructions for use.

An article on the topic - how to cure ARVI quickly at home.

Instructions for use

Ingaron is the only representative of interferon-gamma in Russia. It is produced by the company Pharmaklon.

Composition of drops, form, storage

Before administration into the nasal passages, the drug must be diluted with saline or water for injection, because it is a white porous powder enclosed in a bottle. The powder contains human interferon-gamma.

The bottle contains ME of lyophilisate for the preparation of a solution for intranasal use. The package also contains a special pipette (dropper cap) for administering the drug into the nose.

Ingaron is stored in a dry place, away from sunlight, and at a temperature not exceeding 25 degrees. The diluted solution is stored for no more than 10 days (only in the refrigerator). An expired drug will not cause much harm, but it will not be of any use.

How does Ingaron work?

Once on the nasal mucosa, the drops act instantly. Already from the first minutes of use, pronounced antiviral protection is noted. Viruses are blocked and do not attach to the nasal mucosa. In parallel with this, the body's immune response is activated.

Indications

The main indications for the use of ingaron in the form of drops are:

  • influenza (prophylactic and therapeutic use), including strains H5N1 and H1N1 (“swine”);
  • various types of ARVI;
  • bird flu (ingaron has a patent for the prevention and treatment of this disease).

To prevent infection, the developers of the drug advise using Ingaron nasal drops for children and adults when visiting crowded places (schools, subways, New Year trees, offices, theaters, etc.), as well as if you are staying on the territory of , where the epidemic threshold for influenza and ARVI is exceeded.

When there is a change in climate, after major operations, on a diet, contact with people already sick with influenza or ARVI, prolonged exposure to the cold, ingaron drops will help protect the body from the potential development of respiratory infections.

Contraindications

Basically, the drug is used without restrictions. According to the official instructions, Ingaron drops are not used in childhood (under 7 years), with severe autoimmune processes, and individual intolerance, which is extremely rare. Ingaron is also not recommended for pregnant and lactating women due to insufficient clinical trials in this group of patients. No side effects were found during use.

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How to properly use and dilute Ingaron drops?

To make Ingaron drops more beneficial, first clean your nose with a saline solution (Aqualor, saline, saline, etc.). The drops are prepared as follows: open a bottle of powder (100,000 IU) with clean hands, then dissolve the entire contents of the bottle in 5 ml of solvent (water for injection). The solution must be shaken well until it becomes homogeneous.

Ingaron is administered intranasally, 2-3 drops into each nasal passage; do not exceed the dosage. For prevention, drops are used every other day (one infusion in the morning), so for 10 days in a row. For the treatment of ARVI and influenza, instillations are increased up to 5 times a day. The course of treatment is a week, but not less than 5 days.

To improve the effect after instillation, perform a light massage of the wings of the nose, then the medicinal substance will be evenly distributed over the entire surface of the mucous membrane of the nasal passages.

How much does ingaron (drops) cost?

As we already know, for intranasal administration we only need a bottle of ME, since ME is used for other purposes. At the pharmacy you can buy one bottle for 250–300 rubles, a full package (5 bottles) costs about rubles.

Are there any analogues of ingaron in drops?

Typically, patients are satisfied with this price, and they rarely have to look for cheaper analogues of ingaron, because one bottle is enough for a course of treatment. But it’s worth noting right away that you won’t find structural analogues. You will have to choose drugs from the interferon group, for example, influferon, anaferon, human leukocyte interleukin, viferon, lokferon, alpharon and others.

The following drugs are most often used for intranasal use:

  • Gripferon (Russia) – a 10 ml bottle costs 250 rubles;
  • human leukocyte interferon (Russia) – solution for intranasal use and inhalation 1000 IU, price 120 rubles per bottle;
  • alpharon (Russia) - lfME powder, price 1100 rubles.

Let's briefly look at these drugs and compare them with Ingaron.

Grippferon

This drug contains not gamma, but alpha 2b human interferon. The action of the drops is aimed at destroying viruses and correcting immunity. The main purpose of the drops is therapeutic and preventive therapy for ARVI and influenza. There are practically no contraindications, except for severe allergic diseases.

On sale you can find bottles of influenza with a volume of 5 or 10 ml. The price for them is 240 or 300 rubles, respectively.

Grippferon has an advantage over many antiviral drugs; it is approved from birth, and is not prohibited for use in pregnant and lactating women.

According to the official instructions for influferon and ingaron, it is clear that the first has advantages for use in all age categories. The second drug is more effective for severe strains of influenza, and the recovery process is faster.

Article on the topic - instructions for using influenza.

Human leukocyte interferon

The active ingredient of the drug is interferon alpha. The drug has a low price. Diluted interferon is used not only for intranasal instillation, but also for inhalation. There are few contraindications and side effects; they are mainly related to allergies. Viral infections and flu are a direct indication for interferon. Pediatricians have been using this remedy since the first months of life.

Unlike ingaron, human leukocyte interferon is therapeutically weaker, but for uncomplicated viral infections it gives good results, and at a low price.

Alfarona

The drug is a structural analogue of influferon, and in terms of its therapeutic effect it can replace ingaron. In the pharmacy chain you can find anti-influenza kits of alfaron + ingaron. In all respects, except price (it is more expensive), it corresponds to influenzaphron.

Frequently asked questions to doctors regarding ingaron drops

Why is ingaron prohibited for children under 7 years of age?

Some practicing doctors, ignoring official instructions, prescribe medications to children ahead of schedule. There are cases, for example, when immunologists and pediatricians use ingaron as early as five years of age. Is it dangerous?

Theoretically, this is not dangerous, because... Interferon gamma is found in our body and is not foreign. On the contrary, during illness there is not enough of it in the body, which is why ingaron drops were developed to help. Due to the lack of clinical trials in children under 7 years of age, this contraindication was determined.

Therefore, in cases involving dangerous strains of influenza (swine, avian), the drug can be used at an earlier age.

Can ingaron be combined with antibiotics?

Some patients mistakenly believe that ingaron is an antibiotic, but this is not the case. Ingaron has a combined effect (antiviral, antitumor, immunomodulating and immunostimulating), and antibiotics are only antibacterial.

Therefore, if a clinical case requires the “connection” of antibacterial drugs, there are no contraindications to combining them with ingaron.

Is it dangerous to use ingaron (drops) and arbidol together?

There is no danger; on the contrary, the drugs enhance each other’s effects, so it is recommended to take them together for severe influenza and ARVI.

Ingaron drops - reviews

To be honest, in desperation I turned to two specialists for help: an immunologist and a homeopath. The fact is that my daughter (8 years old) is often sick. As soon as October comes - tonsillitis, November - ARVI, in winter - influenza, and in the spring there is sure to be a repeat of the viral infection. Not only does the child suffer, but he also misses school and other classes.

The immunologist suggested using ingaron as a prophylactic regimen. Ingaron drops were instilled for the first time at the end of September, then use was resumed a month later. The third course was used in mid-February. We only got sick with ARVI once, but recovered quickly.

The homeopath prescribed Hepar Sulfur 200 peas (5 granules once a week) for 6 months.

I think that everything helped as a whole, thanks to all the doctors.

I bought Ingaron on the advice of a friend, for company. We work in a hotel, there is a large flow of clients, especially since people come from different regions, delivering various viruses to our hotel. We prescribed the remedy ourselves, read about it on the Internet.

When coming to work, they immediately put drops in their nose. The drops were administered according to the following scheme: we introduce drops for 10 days, a break for 20 days. Prevention began on November 1 and ended at the end of February. Maybe we didn’t dose it correctly, but we didn’t get sick with the flu, we didn’t even have any sniffles during the fall and winter.

Got sick this morning. Complaints of general malaise, body temperature 38.5 degrees, severe headache, complete weakness. I called the local doctor. Homeopathic antigrippin granules, warm drinks, and Nurofen were prescribed. They told me to come back in 3 days. I was shocked, because it was a typical flu - without snot, sore throat, etc.

A day later the temperature was already below 40 degrees. I called an ambulance from a private clinic. The temperature dropped. They took tests and determined that I had swine flu. They prescribed bed rest, cranberry juice, rose hips, and Ingaron drops.

In the first days, only analgin helped lower the temperature. On the third day I felt significant relief, but I was on sick leave for 10 days, I think the doctors played it safe so that there would be no complications. I think the drops speeded up my recovery.

Despite the harmlessness of the drops, ingaron is still a drug that not only has a detrimental effect on viruses and corrects the immune system, but also forces the entire defense system to work in increased mode.

Consequently, the drug acts not only on immune cells, but also on many biochemical processes, stimulating the entire body system to carry out a kind of powerful restart.

The procedure for using ingaron drops for prevention and treatment should be determined only by the attending physician. Practicing doctors sometimes deviate from the schemes given in official instructions. This is due to the fact that when observing large groups of patients, doctors have a better understanding of doses and treatment regimens, because in practice, all the advantages and disadvantages of drugs are visible. Be healthy!

And a little about secrets.

If you or your child are often sick and are treated with antibiotics alone, know that you are only treating the effect, not the cause.

So you simply “spare” money to pharmacies and pharmaceutical companies and get sick more often.

STOP! Stop feeding someone you don't know. You just need to boost your immunity and you will forget what it’s like to be sick!

There is a way for this! Confirmed by E. Malysheva, A. Myasnikov and our readers! Read more.

Source: http://lor-explorer.com/lekarstva-ot-nasmorka/kapli-ingaron-instruktsiya-po-primeneniyu-analogi-otzyvy