Abstract erespal syrup

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Erespal - instructions for use, analogs, reviews and release forms (syrup, tablets 80 mg) of the drug for the treatment of cough, hoarseness and sore throat in adults, children and pregnancy

In this article you can read the instructions for use of the drug Erespal. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Erespal in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Erespal in the presence of existing structural analogues. Use for the treatment of cough, hoarseness, sore throat and other infections of the upper and lower respiratory tract in adults, children, as well as during pregnancy and lactation.

Erespal - the anti-inflammatory and antibronchoconstrictor activity of the drug Erespal is due to the fact that fenspiride reduces the production of a number of biologically active substances (cytokines, especially tumor necrosis factor alpha (TNF-alpha), arachidonic acid derivatives, free radicals), which play an important role in the development of inflammation and bronchospasm.

Inhibition of arachidonic acid metabolism by fenspiride is potentiated by blockade of histamine H1 receptors, because histamine stimulates the formation of its products (prostaglandins and leukotrienes). Fenspiride blocks alpha-adrenergic receptors, the stimulation of which is accompanied by an increase in the secretion of the bronchial glands. Thus, fenspiride reduces the effect of a number of factors that contribute to the hypersecretion of proinflammatory factors, the development of inflammation and bronchial obstruction.

Fenspiride also has an antispasmodic effect.

1 film-coated tablet contains fenspiride hydrochloride 80 mg. Excipients: disubstituted calcium phosphate, hypromellose, povidone, colloidal anhydrous silicon, magnesium stearate, titanium dioxide, glycerol, macrogol 6000; 15 pcs in a blister, 2 blisters in a box.

1 ml of syrup - 2 mg of fenspiride hydrochloride. Excipients: honey aroma (honey, rum, alcoholates and alcohol extracts of honey, rose and orange flowers), licorice root extract (concentrated tincture of licorice root, glucose syrup, anise oil) and vanillin extract (aqueous-alcoholic decoction of vanilla pods, glycerin, sunset yellow S dye, methyl parahydroxybenzoate, propyl parahydroxybenzoate, saccharin, sucrose, potassium sorbate, distilled water); in a bottle 150 ml, in a box 1 bottle.

Well absorbed from the gastrointestinal tract. It is excreted mainly in the urine (90%), 10% through the intestines.

Diseases of the upper and lower respiratory tract:

  • rhinopharyngitis and laryngitis;
  • tracheobronchitis;
  • bronchitis (with or without chronic respiratory failure);
  • bronchial asthma (as part of complex therapy);
  • respiratory phenomena (cough, hoarseness, sore throat) with measles, whooping cough, influenza;
  • infectious diseases of the respiratory tract accompanied by cough, when standard antibiotic therapy is indicated;
  • otitis and sinusitis of various etiologies.

Film-coated tablets 80 mg.

Syrup 2 mg/ml (children's form of the drug).

Instructions for use and dosage

For adults, the drug is prescribed 80 mg (1 tablet) 2-3 times a day or 3-6 tablespoons (45-90 ml) of syrup per day. 1 tablespoon contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.

The maximum daily dose is 240 mg. The duration of treatment is determined by the doctor.

Erespal in tablet form is not intended for the treatment of children and adolescents under 18 years of age. For use of the drug in this category of patients, Erespal in the form of syrup is recommended.

For children and adolescents, the drug is prescribed at the rate of 4 mg/kg body weight per day. Children aged 0 to 2 years (body weight up to 10 kg) teaspoons of syrup (10-20 ml) per day, can be added to a bottle with food (1 teaspoon spoon contains 10 mg of fenspiride hydrochloride and 3 gsucrose). Children aged 2 to 16 years (body weight more than 10 kg) tablespoons of syrup (30-60 ml) per day.

The drug should be taken before meals. The syrup should be shaken before use.

  • moderate tachycardia, the severity of which decreases with decreasing dose of the drug
  • gastrointestinal disorders
  • nausea
  • epigastric pain
  • drowsiness
  • erythema, rash, urticaria, angioedema.
  • children under 18 years of age (for tablets);
  • hypersensitivity to the active substance and/or any of the components of the drug.

Use during pregnancy and breastfeeding

Taking the drug during pregnancy is not recommended.

Fenspiride therapy is not a reason to terminate an ongoing pregnancy.

Erespal should not be used during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.

Erespal syrup should be used to treat children and adolescents under 18 years of age.

The drug contains Sunset Yellow S dye, as a result of which taking Erespal can provoke the development of allergic reactions, including asthmatic attacks, especially in people with hypersensitivity to aspirin.

Due to the possible sedative effect when taking histamine H1 receptor blockers, the use of Erespal in combination with drugs that have a sedative effect or with alcohol is not recommended.

Analogues of the drug Erespal

Structural analogues of the active substance:

Similar medications:

Other medicines:

News edited by: admin15, 16:49

Reason: added drug interactions

Source: http://instrukciya-otzyvy.ru/46-erespal-po-primeneniyu-analogi-sirop-tabletki-dlya-lecheniya-kashlya-osiplosti-i-persheniya.html

Erespal (syrup) - instructions for use

Registration number: P N012547/02

International nonproprietary name: fenspiride

Dosage form: syrup

100 ml of syrup contains the active substance: fenspiride hydrochloride - 0.200 g.

Excipients: flavoring composition with hints of honey smell* 0.500 g, licorice root extract 0.200 g, vanilla tincture** 0.400 g, glycerol 22.5 g, methyl parahydroxybenzoate 0.09 g, propyl parahydroxybenzoate 0.035 g; saccharin 0.045 g, sucrose 60.0 g, potassium sorbate 0.19 g; purified water up to 100 ml.

* Ingredients: flavorings, including natural ones, sunflower honey, water, ethanol 1

** Ingredients: natural vanilla flavor and other components, including ethanol 1

1 The total ethanol content in 100 ml of syrup is no more than 0.29 mg

The liquid is brownish-yellow, transparent or slightly opalescent. During storage, sediment may form that disappears with shaking.

Anti-inflammatory, antibronchoconstrictor agent.

An anti-inflammatory agent, has an antiexudative effect, prevents the development of bronchospasm. Shows antagonism with mediators of inflammation and allergy: serotonin, histamine (blockade of H1-histamine receptors), bradykinin. Has a myotropic antispasmodic effect. When administered in large doses, it reduces the production of various inflammatory factors (cytokines, arachidonic acid derivatives, free radicals).

Well absorbed from the gastrointestinal tract.

The maximum concentration in blood plasma after oral administration is achieved after 2.3 ± 2.5 hours (from 0.5 to 8 hours). The half-life is 12 hours.

It is excreted mainly by the kidneys (90%), 10% through the intestines.

Diseases of the upper and lower respiratory tract:

  • Rhinopharyngitis and laryngitis;
  • Tracheobronchitis;
  • Bronchitis (with or without chronic respiratory failure);
  • Bronchial asthma (as part of complex therapy);
  • Respiratory phenomena (cough, hoarseness, sore throat) with measles, whooping cough and influenza;
  • For infectious diseases of the respiratory tract accompanied by cough, when standard antibiotic therapy is indicated.
  • Otitis and sinusitis of various etiologies.

Hypersensitivity to the active substance and/or any of the components of the drug. Children under 2 years of age.

Patients with fructose intolerance, glucose-galactose malabsorption, sucrase/isomaltase deficiency (due to the presence of sucrose in Erespal ® syrup), patients with diabetes mellitus (due to the presence of sucrose in Erespal ® syrup).

Pregnancy and lactation period

There are no or limited data on the use of Erespal ® in pregnant women. Taking the drug during pregnancy is not recommended.

Fenspiride therapy is not a reason to terminate an ongoing pregnancy.

Erespal ® should not be used during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.

Directions for use and doses

STRICTLY FOLLOW YOUR DOCTOR'S RECOMMENDATIONS.

Shake before use.

Adults and teenagers:

From 3 to 6 tablespoons of syrup (45-90 ml) per day, take before meals. Children from 2 years old

Recommended dose 4 mg/kg/day.

  • body weight up to 10 kg: from 2 to 4 teaspoons of syrup per day (or ml), can be added to a bottle with food
  • body weight more than 10 kg: from 2 to 4 tablespoons of syrup per day (or ml), take before meals 1 tablespoon (15 ml of syrup) contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.

1 teaspoon (5 ml of syrup) contains 10 mg of fenspiride hydrochloride and 3 g of sucrose. The duration of treatment is determined by the doctor.

INFORM YOUR DOCTOR ABOUT ANY ADVERSE REACTIONS AND SENSATIONS YOU EXPERIENCE, INCLUDING THOSE NOT MENTIONED IN THIS INSTRUCTION, AS WELL AS CHANGES IN LABORATORY VALUES DURING THE THERAPY.

The most common adverse reactions to the drug Erespal ® are observed in the digestive system. The frequency of adverse reactions that may occur during therapy is given in the following gradation: very often (>1/10); often (>1/100, <1/10); uncommon (>1/1000, <1/100); rare (>1/10000, <1/1000); very rare (<1/10000) and unknown frequency (frequency cannot be calculated from available data). From the cardiovascular system

Rarely: moderate tachycardia, the severity of which decreases with decreasing dose of the drug. Unknown frequency*: palpitations, hypotension, possibly associated with tachycardia. From the digestive system

Common: gastrointestinal disorders, nausea, epigastric pain.

Unknown frequency*: diarrhea, vomiting.

From the central nervous system

Unknown frequency*: dizziness. Common disorders and symptoms

Unknown frequency*: asthenia, increased fatigue.

From the skin and subcutaneous fat

Rarely: erythema, rash, urticaria, angioedema, fixed erythema pigmentosa.

Unknown frequency*: pruritus, toxic epidermal necrolysis, Stevens-Johnson syndrome.

* Data from post-registration use.

In case of an overdose of the drug (cases of overdose have been reported when taking the drug at a dose of more than 2320 mg), you should immediately seek medical help.

Symptoms: drowsiness or agitation, nausea, vomiting, sinus tachycardia.

Treatment: gastric lavage, electrocardiogram (ECG) monitoring. Maintaining vital body functions.

Interaction with other drugs

No special studies have been conducted on the interaction of fenspiride with other drugs. Due to the possible enhancement of the sedative effect when taking histamine H1 receptor blockers, it is not recommended to use Erespal ® syrup in combination with drugs that have a sedative effect, or in combination with alcohol.

The drug contains parabens (parahydroxybenzoates), as a result of which taking this drug can provoke the development of allergic reactions, including delayed ones.

When prescribing the drug to patients with diabetes, it is necessary to take into account that Erespal ® syrup contains sucrose (1 teaspoon - 3 g of sucrose = 0.3 XE; 1 tablespoon - 9 g of sucrose = 0.9 XE).

No studies have been conducted to study the effect of Erespal ® on the ability to drive vehicles and operate machinery. Patients should be aware of the possible development of drowsiness when taking the drug Erespal ®, especially at the beginning of therapy or when combined with alcohol intake, and should be careful when driving vehicles and when performing work that requires a high speed of psychomotor reactions.

Produced by Servier Industry Laboratory, France:

Syrup 2 mg/ml. 150 ml of syrup in a brown plastic bottle (PVC) with a plastic cap with tamper evident. One bottle with instructions for medical use is placed in a cardboard box.

During production at Pharmstandard-Leksredstva OJSC, Russia:

Syrup 2 mg/ml. 150 ml or 250 ml of syrup in a brown plastic bottle (PVC) with a plastic cap with tamper evident.

One bottle with instructions for medical use is placed in a cardboard box.

No special storage conditions are required. Keep out of the reach of children.

3 years. Do not use after the expiration date indicated on the package.

Source: http://med2c.ru/%D1%8D%D1%80%D0%B5%D1%81%D0%BF%D0%B0%D0%BB-%D0%B8%D0%BD%D1% 81%D1%82%D1%80%D1%83%D0%BA%D1%86%D0%B8%D1%8F-%D0%BF%D0%BE-%D0%BF%D1%80%D0% B8%D0%BC%D0%B5%D0%BD%D0%B5%D0%BD%D0%B8%D1%8E/

Erespal syrup: Instructions for use

Erespal syrup is preferable to tablets due to the absence of age restrictions. This drug can be prescribed to both adults and newborns; the only difference is the dosage, which is calculated in addition to age based on body weight.

Indications for the use of Erespal syrup are the same as for the use of tablets: inflammatory - both acute and chronic diseases of the respiratory tract (upper and lower sections), as well as otitis, allergic rhinitis and other allergic manifestations affecting the functioning of the respiratory system. The list of diseases for which the use of this remedy is recommended also includes influenza, measles, and whooping cough.

Composition and release form

Erespal syrup is an orange, transparent liquid; There is rarely a sediment, when it appears, it is recommended to shake the syrup.

1 ml. syrup - 2 mg fenspiride hydrochloride.

Excipients: honey aroma (honey, rum, alcoholates and alcohol extracts of honey, rose and orange flowers), licorice root extract (concentrated tincture of licorice root, glucose syrup, anise oil) and vanillin extract (aqueous-alcoholic decoction of vanilla pods, glycerin, sunset yellow S dye, methyl parahydroxybenzoate, propyl parahydroxybenzoate, saccharin, sucrose, potassium sorbate, distilled water).

150 ml bottle, 1 bottle in a box.

Indications for use

Has an anti-inflammatory effect in the respiratory tract. Indications: rhinopharyngitis, laryngitis; otitis, sinusitis; rhinotracheobronchitis; bronchitis; bronchial asthma, respiratory phenomena due to measles, whooping cough and influenza (syrup).

  • rhinopharyngitis and laryngitis;
  • otitis and sinusitis;
  • rhinotracheobronchitis;
  • bronchitis;
  • maintenance therapy for isolated and complicated bronchial asthma;
  • respiratory phenomena during measles, whooping cough, influenza (for syrup).

Directions for use and doses

The syrup is taken orally.

For adults

Before meals, 3-6 tablespoons of syrup (45-90 ml) daily.

For children from 2 to 18 years old

The daily dose is 2-4 tablespoons of syrup (30-60 ml).

Infants and children under 2 years of age

Or children weighing less than 10 kg.

The daily dose is 4 mg per 1 kg of body weight, which is approximately: 2-4 teaspoons of syrup (10-20 ml).

Erespal syrup can be added to baby food bottles.

special instructions

Erespal in syrup form is prescribed with caution to patients with hypersensitivity to acetylsalicylic acid and other NSAIDs due to the risk of allergic reactions (including bronchospasm) in this category of patients due to the fact that the syrup contains Sunset Yellow S dye .

For infectious diseases, Erespal is used in combination with standard antibiotic therapy.

Erespal in the form of syrup is prescribed with caution to patients with diabetes mellitus, because. Dosage adjustment of hypoglycemic agents may be required.

Storage conditions

In places inaccessible to children. No special temperature regime is required.

Shelf life

Erespal is a bronchodilator and anti-inflammatory drug intended for the treatment of inflammatory diseases of the upper and lower respiratory tract.

Table of contents:

Erespal tablets instructions. Indications: bronchial asthma, bronchospasm, chronic bronchitis (including with respiratory failure), allergic rhinitis.

All materials presented on the site are for informational and informational purposes only and cannot be considered a guide to treatment or the choice of certain treatments.

Do not self-medicate. At the first signs of a disease, consult a doctor; only a doctor has the competence to diagnose the disease and the right to prescribe medications.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://site-zdorovie.ru/opisanie-lekarstv/erespal-sirop-instrukciya-po-primeneniyu.htm

Erespal

Manufacturer: Servier (Sevier) France

ATS code: R03DX03

Release form: Solid dosage forms. Pills.

General characteristics. Compound:

Active substance: fenspiride hydrochloride - 80 mg.

Excipients: calcium hydrogen phosphate 104.5 mg; hypromellose 100 mg; povidone 12.80 mg; colloidal silicon dioxide anhydrous 0.50 mg; magnesium stearate 2.20 mg;

Shell: titanium dioxide 0.841 mg; glycerol 0.263 mg; hypromellose 4.370 mg; macrogol, 263 mg; magnesium stearate 0.263 mg.

Round, biconvex, film-coated tablets, white.

Pharmacological properties:

Pharmacodynamics. The anti-inflammatory and antibronchoconstrictor activity of fenspiride is due to a decrease in the production of a number of biologically active substances (cytokines, especially factor

tumor necrosis α (TNF-α), arachidonic acid derivatives, free radicals), which play an important role in the development of inflammation and bronchospasm. The inhibition of arachidonic acid metabolism by fenspiride is potentiated by its H1-antihistamine effect, because histamine stimulates the metabolism of arachidonic acid with the formation of prostaglandins and leukotrienes. Fenspiride blocks α-adrenergic receptors, the stimulation of which is accompanied by an increase in the secretion of the bronchial glands. Thus, fenspiride reduces the effect of a number of factors that contribute to the hypersecretion of proinflammatory factors, the development of inflammation and bronchial obstruction. Fenspiride also has an antispasmodic effect.

Pharmacokinetics. Cmax after oral administration is achieved within 6 hours. T1/2 –12 hours.

It is excreted primarily by the kidneys.

Indications for use:

Diseases of the upper and lower respiratory tract:

• Respiratory phenomena (cough, hoarseness, sore throat) with measles, whooping cough and influenza

• For infectious diseases of the respiratory tract accompanied by cough, when standard antibiotic therapy is indicated

Otitis and sinusitis of various etiologies.

Directions for use and dosage:

Adults: 1 tablet 2-3 times a day.

The maximum daily dose is 240 mg.

The duration of treatment is determined by the doctor.

Features of application:

Erespal® syrup should be used to treat children and adolescents under 18 years of age.

No studies have been conducted to study the effect of Erespal® on the ability to drive vehicles and operate machinery. Patients should be aware of the possible development of drowsiness while taking Erespal®, especially at the beginning of therapy or when combined with alcohol intake, and should be careful when driving vehicles and when performing work that requires a high speed of psychomotor reactions.

Side effects:

The frequency of adverse reactions that may occur during therapy is given as

the following gradation: very often (>1/10); often (>1/100, <1/10); uncommon (>1/1000, <1/100);

rare (>1/10000, <1/1000); very rare (<1/10000) and unknown frequency (frequency not

can be calculated from available data).

From the cardiovascular system

Rarely: moderate tachycardia, the severity of which decreases with decreasing dose of the drug.

From the digestive system:

Common: gastrointestinal disorders, nausea, epigastric pain.

From the central nervous system:

Common disorders and symptoms:

Unknown frequency: asthenia, increased fatigue.

For the skin and subcutaneous fat:

Rare: erythema, rash, urticaria, angioedema, fixed pigmentation

Interaction with other drugs:

No special studies have been conducted on the interaction of fenspiride with other drugs. Due to the possible increase in sedative effect when taking histamine H1-blockers

receptors, it is not recommended to use Erespala® in combination with drugs that have a sedative effect, or in combination with alcohol.

Contraindications:

Hypersensitivity to the active substance and/or any of the components of the drug.

Children under 18 years of age (Erespal® syrup should be used to treat children and adolescents under 18 years of age).

PREGNANCY AND BREASTFEEDING

Taking the drug during pregnancy is not recommended. Fenspiride therapy is not a reason to terminate an ongoing pregnancy. There are no clinical data on the fetotoxic effect of fenspiride or its ability to cause malformations when taken during pregnancy. Erespal® should not be used during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.

Overdose:

In case of an overdose of the drug (cases of overdose have been reported when taking the drug at a dose of more than 2320 mg), you should immediately seek medical help.

Treatment: gastric lavage, electrocardiogram (ECG) monitoring. Maintaining vital body functions.

Storage conditions:

At a temperature not higher than 25°C. Keep out of the reach of children. List B. EXPIRATION DATE 3 years.

DO NOT USE AFTER THE EXPIRY DATE STATED ON THE PACKAGING.

Vacation conditions:

Package:

Film-coated tablets, 80 mg.

15 tablets per blister (PVC/Al). 2 blisters with instructions for medical use per cardboard pack.

Published: July 10, 2013

Similar drugs

Drugs acting on the respiratory system.

Drugs acting on the respiratory system. Other agents for systemic use in obstructive respiratory diseases.

Drugs acting on the respiratory system.

Anti-inflammatory, antibronchoconstrictor agent.

Source: http://www.24farm.ru/preparats/erespal_servier/

ERESPAL

Active substance: fenspiride

ATX code: R03DX03

KFG: A drug with anti-inflammatory and antibronchoconstrictor activity

Reg. number: P No. 012547/02

Registration date: 08.26.05

Owner reg. Credit: Les Laboratoires SERVIER

DOSAGE FORM, COMPOSITION AND PACKAGING

White film-coated tablets, round, biconvex.

Excipients: calcium hydrogen phosphate, hypromellose, povidone, colloidal anhydrous silicon dioxide, magnesium stearate, titanium dioxide, glycerol, macrogol 6000.

15 pcs. - blisters (2) - cardboard packs.

The syrup is transparent, orange in color, sometimes with a small sediment that disappears when shaken.

Excipients: flavoring composition with hints of honey scent, natural condensed licorice extract, vanilla tincture, glycerol, Sunset Yellow CFC, methyl parahydroxybenzoate, propyl parahydroxybenzoate, saccharin, sucrose, potassium sorbate, water.

150 ml - dark plastic bottles (1) - cardboard packs.

The description of the drug is based on the officially approved instructions for use.

The anti-inflammatory and antibronchoconstrictor activity of the drug Erespal is due to the fact that fenspiride reduces the production of a number of biologically active substances (cytokines, especially tumor necrosis factor α (TNF-β), arachidonic acid derivatives, free radicals), which play an important role in the development of inflammation and bronchospasm. Inhibition of arachidonic acid metabolism by fenspiride is potentiated by blockade of histamine H1 receptors , because histamine stimulates the formation of its products (prostaglandins and leukotrienes). Fenspiride blocks β-adrenergic receptors, the stimulation of which is accompanied by an increase in the secretion of bronchial glands. Thus, fenspiride reduces the effect of a number of factors that contribute to the hypersecretion of proinflammatory factors, the development of inflammation and bronchial obstruction. Fenspiride is also characterized by the presence of antispasmodic activity.

Absorbed from the gastrointestinal tract relatively slowly. After oral administration of tablets, Cmax is achieved after 6 hours, after taking syrup - after 2.3±2.5 hours (from 0.5 to 8 hours).

T1 /2 is 12 hours. It is excreted mainly in the urine.

Diseases of the upper and lower respiratory tract:

- nasopharyngitis and laryngitis;

- otitis and sinusitis of various etiologies, including allergic (both seasonal and permanent);

- bronchitis (with or without chronic respiratory failure);

- complicated or isolated bronchial asthma (maintenance therapy);

- respiratory phenomena with measles, whooping cough, influenza.

For adults, the drug is prescribed 80 mg (1 tablet) 2-3 times a day or 3-6 tablespoons (45-90 ml) of syrup per day. 1 tablespoon contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.

Erespal in tablet form is not intended for the treatment of children under 14 years of age. For use of the drug in children under 14 years of age, Erespal in the form of syrup is recommended.

For children and adolescents under the age of 14 years, the drug is prescribed at the rate of 4 mg/kg body weight/day. For children aged 0 to 2 years (body weight up to 10 kg), teaspoons of syrup (10-20 ml)/day can be added to a bottle with food (1 teaspoon contains 10 mg of fenspiride hydrochloride and 3 g of sucrose). Children aged 2 to 16 years (body weight more than 10 kg) tablespoons of syrup (30-60 ml)/day.

Course of treatment days. A repeated course is possible after consultation with a doctor.

The drug should be taken before meals. The syrup should be shaken before use.

From the digestive system: nausea, stomach pain, vomiting.

Allergic reactions: very rarely - erythema, angioedema, fixed erythema pigmentosa, rash; Due to the presence of para-hydroxybenzoate in the syrup, urticaria may develop.

Other: drowsiness; rarely - moderate tachycardia, disappearing after discontinuation of the drug.

- children under 14 years of age (for tablets);

- hypersensitivity to the active substance and/or any of the components of the drug, especially to the Sunset yellow CFC dye, methyl and propylparabens (for syrup).

It is not recommended to use Erespal during pregnancy due to the lack of sufficient clinical data. Fenspiride therapy is not a reason to terminate an ongoing pregnancy.

While taking Erespal during lactation, you should stop breastfeeding, because There is no data on the excretion of fenspiride in breast milk.

If the disease is infectious, treatment with Erespal is carried out in combination with standard antibiotic therapy.

Erespal in the form of syrup is prescribed with caution to patients with hypersensitivity to acetylsalicylic acid and other NSAIDs due to the risk of allergic reactions (including bronchospasm) in this category of patients due to the fact that the syrup contains Sunset Yellow CFC dye .

Since the syrup contains sucrose, it should be administered to patients with diabetes mellitus with caution, because Dosage adjustment of hypoglycemic drugs may be required.

Due to the presence of sucrose, Erespal in syrup form should not be administered to patients with fructose intolerance, glucose-galactose malabsorption syndrome or sucrazoisomaltase deficiency (a rare metabolic disorder).

Symptoms: drowsiness or agitation, nausea, vomiting, sinus tachycardia.

Treatment: gastric lavage, ECG monitoring.

Drug interactions with Erespal have not been described.

The drug is available with a doctor's prescription.

List B. The drug should be stored out of the reach of children at a temperature not exceeding 25°C. The shelf life of tablets is 2 years, syrup - 3 years. Do not use after the expiration date indicated on the package.

Source: http://docvita.ru/Details/ERESPAL.html

Erespal syrup for children: instructions for use

Erespal syrup for children represents a clinical and pharmacological group of drugs with antiallergic, anti-inflammatory, and antispasmodic effects. It is used for children and adults to treat inflammatory pathologies mainly of the respiratory system, which is accompanied by spasm of hollow structures.

Compound

Erespal syrup for children is a transparent (slight opalescence is allowed) yellow-brown liquid. The main active ingredient of the drug is fenspiride hydrochloride, its content in 1 ml of syrup is 2 mg. Excipients include:

  • Licorice root extract.
  • Sucrose.
  • Vanilla tincture.
  • Glycerol.
  • Potassium sorbate.
  • Glycerol.
  • Methyl parahydroxybenzoate.
  • Propyl parahydroxybenzoate.
  • Flavoring composition.
  • Purified water.

Erespal syrup for children is in a dark plastic bottle of 150 ml. The cardboard pack contains 1 bottle of syrup and annotation.

Action

The main active component of Erespal syrup for children, fenspiride, suppresses the activity of a number of biologically active compounds that are produced at the site of the pathological process (cytokines, tumor necrosis factor, prostaglandins, which are a chemical derivative of arachidonic acid). Due to the suppression of biologically active compounds, several therapeutic effects of the drug are realized, which include:

  • Anti-inflammatory effect – reducing the severity of inflammation, namely pain, tissue swelling and hyperemia (increased blood supply to tissue vessels in the area of ​​the pathological process).
  • Antihistamine effect - blocking H-histamine receptors, which are responsible for the development of an allergic reaction with the appearance of discomfort in the form of itching, burning, bronchospasm, tissue swelling.
  • The antispasmodic effect is a decrease in the tone of the smooth muscles of the respiratory tract, namely the bronchi of various sizes with the expansion of their lumen.

After taking Erespal syrup for children orally, the active substance is well absorbed into the systemic bloodstream. It is processed in the liver, and breakdown products are excreted primarily in the urine. The half-life (the time it takes to eliminate half of the entire dose of the drug) is about 12 hours.

Indications

The main medical indication for taking Erespal syrup in children is the presence of inflammatory pathology of the respiratory system, which includes:

  • Acute or chronic bronchitis is inflammation of the bronchial mucosa caused by various reasons.
  • Tracheobronchitis is a combined inflammation of the trachea and bronchi.
  • Rhinopharyngitis is a lesion of the nasal and pharyngeal mucosa.
  • Laryngitis is an inflammatory lesion of the larynx.
  • Otitis and sinusitis are diseases of the middle ear and paranasal sinuses.

Taking the drug is also indicated during combination therapy for infectious pathologies localized in the respiratory organs.

Contraindications

Taking Erespal syrup for children is contraindicated in the presence of individual intolerance to any of the components of the drug, as well as in children under 2 years of age. The drug is used with caution against the background of concomitant disturbances in the digestion and absorption of carbohydrates (glucose-galactose malabsorption, deficiency of the digestive enzyme lactase), as well as in patients with diabetes mellitus. Before starting to use the drug, it is important to ensure that there are no contraindications.

Dosage

Erespal syrup for children is taken orally. The bottle should be shaken well before use. The average therapeutic dosage for children over 2 years of age is 4 mg of the active ingredient per 1 kg of body weight. For a child weighing up to 10 kg, the average dose is 2-4 teaspoons per day before meals. For body weight more than 10 kg - 2-4 tablespoons. For children over 12 years of age and adults, the therapeutic dose varies from 3 to 6 tablespoons per day. The duration of therapy using Erespal syrup is determined individually by the attending physician.

Side effects

With the use of Erespal syrup, the development of negative reactions from various organs and systems is possible:

  • Digestive system - nausea, pain in the stomach, less often vomiting and diarrhea (diarrhea) may develop.
  • Nervous system – drowsiness, periodic dizziness.
  • Cardiovascular system - a moderate increase in heart rate (tachycardia), a decrease in systemic blood pressure, and the appearance of an unpleasant sensation of palpitations.
  • Skin and subcutaneous tissue - redness, less often rash, itching of the skin, necrotizing dermatitis with the death of a significant number of skin cells.

If signs of negative reactions develop while taking Erespal syrup, you should contact a medical specialist.

Peculiarities

Before you start using Erespal syrup, it is important to carefully read the instructions for it, and also pay attention to several special instructions:

  • The drug contains parabens, which can cause delayed allergic reactions.
  • Erespal syrup contains sucrose, which should be taken into account when using it in patients with concomitant diabetes mellitus.
  • The drug is not recommended for pregnant women, as its safety remains unclear.
  • After taking the drug, it is not recommended to engage in activities that require increased concentration of attention and speed of psychomotor reactions.

In the pharmacy chain, Erespal syrup for children is available with a prescription. Self-administration of the drug without a doctor's prescription is not recommended.

Overdose

If the recommended therapeutic dosage of Erespal syrup is significantly exceeded, drowsiness or agitation, nausea, periodic vomiting, and increased heart rate develop. Treatment of overdose consists of gastric lavage, taking enterosorbents (activated carbon), as well as prescribing symptomatic therapy. There is no specific antidote for the drug today.

Analogs of syrup for children Erespal

For the drug Erespal, similar ones are Fenspiride, Eladon, Epistat.

Storage

The shelf life of Erespal syrup for children is 3 years. It should be stored in its original packaging, in a dark, dry place, out of reach of children, at an air temperature not exceeding +25° C.

The average cost of a package of Erespal syrup for children in Moscow pharmacies varies within rubles.

Source: http://bezboleznej.ru/erespal-sirop-dlya-detey

Erespal - instructions for use. How to give Erespal syrup to children and adults for cough or bronchitis

This drug has become a popular remedy in the treatment of the respiratory system. The demand for the drug is explained by its effectiveness and safety. The product effectively helps eliminate painful symptoms and speed up recovery. However, when using, the characteristics of a potent medication should be taken into account.

Erespal - instructions

The medicine belongs to the group of anti-inflammatory and antibronchoconstrictor (preventing bronchospasms) drugs. Erespal is produced in France. Tablets are intended for adults, and for children the drug is produced in the form of syrup. The active ingredient of the drug is fenspiride hydrochloride, thanks to which the drug Erespal performs 4 functions in one. This is at the same time:

  • anti-inflammatory agent;
  • an antihistamine that prevents swelling of the mucous membranes;
  • an antispasmodic that prevents dangerous narrowing of the bronchi and suffocation;
  • mucolytic, thinning thick sputum.

For what diseases can Erespal be taken - the instructions for use indicate that these are pathologies of the respiratory tract. Indications of the medication:

For what cough is Erespal taken? The medicine is universal, effectively suppressing dry and wet cough in adults and children. In addition, according to the instructions for use, the medication eliminates:

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  • sore throat;
  • nasal congestion, runny nose;
  • swelling.

Erespal syrup

When children have a strong cough, they readily drink this sweet orange medicine with a honey-vanilla aroma. Erespal in syrup is also suitable for adults, but it contains sucrose, which is not suitable for treatment for diabetics. The drug is sold in 150 ml bottles, although it is cheaper if you purchase the medicine with a capacity of 250 ml. 1 ml of syrup contains 2 mg of fenspiride hydrochloride. Erespal's abstract notes an important feature of the drug: the main medicinal substance is enriched with licorice, which is known for its powerful antitussive activity. The product begins to act after 2.5 hours.

Erespal tablets

The drug reaches its maximum concentration in the body 6 hours after administration. Erespal is in film-coated tablets that have a standard biconvex shape, packaged in 30 pieces per package. Each contains 80 mg of fenspiride hydrochloride. Excipients - calcium, silicon, magnesium compounds and other ingredients. The use of Erespal in tablets, as indicated in the instructions, is intended for adult patients and adolescents.

Erespal - dosage

The therapeutic effect depends on the concentration of the drug in the body. How to take Erespal? The standard method of use for adults is 2, maximum 3 tablets per day before or after meals. The dosage of syrup is from 3 to 6 tablespoons three times a day. At the same time, the amount of fenspiride ranges from 90 to 180 mg - the difference is big. So Erespal - the instructions for use of which provide conflicting information about doses - should be prescribed by a doctor. When calculating them, the type, severity of the disease, and the age of the patient should be taken into account in order to prevent an overdose.

Erespal - dosage for children

With kids the situation is simpler. How to take Erespal for children who are already 2 years old? A baby whose weight has not reached 10 kg should be given 20 ml of syrup, no more. For a child weighing more than 10 kg, the instructions set a maximum of 60 ml. Children's dosage should always be rounded down. For reference: 20 ml is approximately 4 teaspoons, 60 ml is 4 tablespoons of syrup. The medicine can be masked by mixing with water or tea without sugar.

Erespal for adults

In most cases, the instructions for use recommend the drug for this category of patients. Erespal for adults:

  • quickly relieves inflammatory symptoms;
  • eliminates the root cause of the disease;
  • does not require the prescription of numerous medications;
  • extremely rarely causes allergic reactions;
  • shortens recovery time.

According to the instructions for use, another advantage of the drug is its good compatibility with antibiotics, many tablets, and mixtures, the effectiveness of which is not suppressed. Thus, the product is quite compatible with analogues, for example, the domestic expectorant medicine based on marshmallow Mucaltin or the French syrup Fluditec, which has a similar effect. Interaction with Indian Ascoril, containing bromhexine, salbutamol and guaifenesin, is also effective. The drug is incompatible with alcohol, as it enhances the sedative (calming) effect.

Erespal - side effects

Complaints about the negative effects of this drug are extremely rare. However, when taking Erespal - the instructions for its use warn about this - undesirable effects are possible. Sometimes individual intolerance to the ingredients of the medicine affects it. Erespal - the side effects of which cannot be ruled out - can cause:

  • pain in the solar plexus area;
  • nausea;
  • dizziness;
  • diarrhea;
  • drowsiness;
  • feeling tired;
  • cardiopalmus
  • skin itching, rash.

Erespal - contraindications

In the vast majority of patients, fenspiride does not cause negative reactions. However, prescribing Erespal to children - the instructions for its use emphasize this - in the form of tablets is allowed for a child only after 14 years, and in syrup - after 2 years, since allergies may occur. The use of the drug during pregnancy is not recommended - it is unknown what kind of reaction to it there may be, since relevant studies have not been conducted. The instructions do not contain information about how Erespal works during lactation, so it is better not to take the drug during this period.

Price for Erespal

The cost of the medicine and the price of analogues depend on the packaging and category of the pharmacy. You can buy the medicine inexpensively in an online store by ordering from a catalog. How much does Erespal cost in tablets? The approximate price of 30 tablets is from 340 to 430 rubles. The syrup costs about the same: the price of a bottle is 150 ml - rubles, 250 ml - rubles. The French original drug can be replaced with analogues that also contain fenspiride. This is the domestic Eladon, price - rubles, Erispirus (Slovenia), price - rubles.

Video: medicine Erespal - instructions

Reviews

I get the flu almost every winter. And it’s hard, with swelling, tears, and a persistent cough. I have tried all sorts of remedies! The instructions for use promise one thing, but in reality it often turns out to be something completely different. One doctor recommended Erespal to me. This is a really good medicine, its use quickly puts you on your feet.

I had the flu on my legs and got a complication in the form of sinusitis. I wouldn’t wish such a misfortune on anyone! My head was pounding with pain. I was terribly afraid to get a puncture, and besides, I was told that it is not always effective. The doctor prescribed rinsing and this drug, thanks to which I avoided a puncture.

For colds and viral infections, this is my very first remedy. As soon as my nose starts to squelch, I immediately re-read the instructions for its use. I drink it myself and add it to my daughter’s tea. We do not experience any side effects or allergic reactions, and the price of the medication is reasonable. I always have this product in my home medicine cabinet.

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and make recommendations for treatment based on the individual characteristics of a particular patient.

Source: http://sovets.net/8489-erespal-instrukciya-po-primeneniyu.html

ERESPAL

Syrup in the form of a brownish-yellow liquid, transparent or slightly opalescent; During storage, sediment may form, which disappears with shaking.

Excipients: flavoring composition with hints of honey smell (flavors, including natural, sunflower honey, water, ethanol*) mg, licorice root extract, vanilla tincture (natural vanilla flavor and other components, including ethanol* ) mg, glycerol - 22.5 g, methyl parahydroxybenzoate - 90 mg, propyl parahydroxybenzoate - 35 mg, saccharin - 45 mg, sucrose - 60 g, potassium sorbate mg, purified water - up to 100 ml.

* total ethanol content in 100 ml of syrup is no more than 0.29 mg.

150 ml - brown plastic bottles (1) - cardboard packs.

150 ml - brown plastic bottles (1) complete with a measuring cup - cardboard packs.

250 ml - brown plastic bottles (1) - cardboard packs.

250 ml - brown plastic bottles (1) complete with a measuring cup - cardboard packs.

An anti-inflammatory agent, has an antiexudative effect, prevents the development of bronchospasm. Shows antagonism with mediators of inflammation and allergy: serotonin, histamine (blockade of H1 - histamine receptors), bradykinin. It has a myotropic antispasmodic effect.

When administered in large doses, it reduces the production of various inflammatory factors (cytokines, arachidonic acid derivatives, free radicals).

Well absorbed from the gastrointestinal tract. After oral administration, Cmax is achieved within 2.3±2.5 hours (from 0.5 to 8 hours).

T1 /2 is 12 hours. It is excreted mainly by the kidneys (90%), 10% through the intestines.

Diseases of the upper and lower respiratory tract:

- nasopharyngitis and laryngitis;

- bronchitis (with or without chronic respiratory failure);

- respiratory phenomena (cough, hoarseness, sore throat) with measles, whooping cough, influenza;

- infectious diseases of the respiratory tract, accompanied by cough, when standard antibiotic therapy is indicated.

Otitis and sinusitis of various etiologies.

- children under 2 years of age;

- hypersensitivity to the active substance and/or any of the components of the drug.

With caution: patients with fructose intolerance, glucose-galactose malabsorption, sucrase/isomaltase deficiency (due to the presence of sucrose in Erespal syrup), patients with diabetes mellitus (due to the presence of sucrose in Erespal syrup).

The drug is taken orally, before meals. The syrup should be shaken before use.

For adults and adolescents, the drug is prescribed 3-6 tablespoons or 3-6 measuring cups filled to 15 ml, which corresponds to ml/day. The daily dose can be divided into several doses (from 3 to 6).

For children over 2 years of age, the drug is prescribed at the rate of 4 mg/kg body weight/day. For children weighing up to 10 kg, teaspoons or 2-4 measuring cups filled to 5 ml, which corresponds to ml/day, can be added to the feeding bottle. For children weighing more than 10 kg, tablespoons or 2-4 measuring cups filled to 15 ml, which corresponds to ml/day. The daily dose can be divided into several doses (from 2 to 4).

1 tablespoon or 1 measuring cup filled to 15 ml (15 ml syrup) contains 30 mg fenspiride hydrochloride and 9 g sucrose.

1 teaspoon or 1 measuring cup filled to 5 ml (5 ml syrup) contains 10 mg fenspiride hydrochloride and 3 g sucrose.

The duration of treatment is determined by the doctor.

The most common adverse reactions to the drug Erespal are observed in the digestive system.

The frequency of adverse reactions that may occur during therapy is given in the following gradation: very often (>1/10); often (>1/100, <1/10); uncommon (>1/1000, <1/100); rare (>1/10,000, <1/1000); very rare (<1/10,000); unknown frequency (frequency cannot be calculated from available data).

From the cardiovascular system: rarely - moderate tachycardia, the severity of which decreases with decreasing dose of the drug; unknown frequency* - palpitations, hypotension, possibly associated with tachycardia.

From the digestive system: often - gastrointestinal disorders, nausea, epigastric pain; unknown frequency* - diarrhea, vomiting.

From the side of the central nervous system: rarely - drowsiness; unknown frequency* - dizziness.

From the skin and subcutaneous fat: rarely - erythema, rash, urticaria, angioedema, fixed erythema pigmentosa; unknown frequency* - itching, toxic epidermal necrolysis, Stevens-Johnson syndrome.

General disorders and symptoms: unknown frequency* - asthenia, increased fatigue.

* Data from post-registration use.

The patient should be informed of the need to inform the doctor about any, incl. adverse reactions not mentioned above, as well as changes in laboratory parameters during therapy with Erespal.

In case of an overdose of the drug (cases of overdose have been reported when taking the drug at a dose of more than 2320 mg), you should immediately seek medical help.

Symptoms: drowsiness or agitation, nausea, vomiting, sinus tachycardia.

Treatment: gastric lavage, ECG monitoring. Maintaining vital body functions.

No special studies have been conducted on the interaction of fenspiride with other drugs.

Due to the possible increase in sedative effect when taking histamine H1 receptor blockers, it is not recommended to use Erespal syrup in combination with drugs that have a sedative effect, or in combination with alcohol.

The drug contains parabens (parahydroxybenzoates), as a result of which taking this drug can provoke the development of allergic reactions, incl. deferred.

When prescribing the drug to patients with diabetes, it is necessary to take into account that Erespal syrup contains sucrose (1 teaspoon or 1 measuring cup filled with up to 5 ml of syrup - 3 g of sucrose = 0.3 XE; 1 tablespoon or 1 measuring cup filled with up to 15 ml of syrup - 9 g sucrose = 0.9 XE).

Impact on the ability to drive vehicles and operate machinery

No studies have been conducted to study the effect of Erespal on the ability to drive vehicles and operate machinery. Patients should be aware of the possible development of drowsiness while taking Erespal, especially at the beginning of therapy or when combined with alcohol intake, and should be careful when driving vehicles and when performing work that requires a high speed of psychomotor reactions.

There are no or limited data on the use of Erespal in pregnant women. Taking the drug during pregnancy is not recommended.

Fenspiride therapy is not a reason to terminate an ongoing pregnancy.

Erespal should not be used during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.

Contraindicated in children under 2 years of age.

The drug should be stored out of the reach of children, at temperatures above 25°C. Shelf life: 3 years. Do not use after the expiration date indicated on the package.

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Source: http://health.mail.ru/drug/erespal_1/