Tobrex for nose instructions

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Tobrex - instructions for use, analogues, reviews, price

Tobrex eye drops

Release forms

  • Eye drops: 0.3% solution 5 ml in a sterile plastic dropper bottle.

1 ml of solution contains Tobramycin 3 mg and excipients.

  • Eye ointment 0.3%, 3.5 g in an aluminum tube.

    • Table of contents:

    Instructions for use of Tobrex eye drops

    Indications for use

    • Conjunctivitis (inflammation of the mucous membrane of the eye);
    • keratoconjunctivitis;
    • keratitis (inflammation of the cornea);
    • blepharoconjunctivitis;
    • blepharitis (inflammation of the edges of the eyelids);
    • dacryocystitis (inflammation of the lacrimal sac);
    • iridocyclitis (inflammation of the iris and ciliary body of the eyeball);
    • endophthalmitis (purulent inflammation of the inner membranes of the eyeball);
    • meibomitis (inflammation of the sebaceous glands of the eyelids).

    Tobrex is effective in treating these diseases if they are caused by bacteria sensitive to Tobramycin.

    Contraindications

    Side effects

    Treatment with Tobrex drops

    1. Wash your hands thoroughly with soap;

    2. Take a bottle with drops and shake several times;

    3. Open the bottle;

    4. Tilt your head back;

    5. Pull down the lower eyelid;

    6. Holding the bottle vertically and without touching the tip to the mucous membrane and eyelid, drop the medicine into the lower conjunctival sac, gently pressing the bottom of the bottle with your index finger;

    7. Release the lower eyelid and close the eye;

    8. Gently press your finger on the inner corner of the eye and hold for a couple of minutes;

    9. If you need to drip Tobrex into both eyes, then repeat the procedure for the second eye;

    10. Close the bottle.

    Adult patients are prescribed 1-2 drops every 4 hours into the lower conjunctival sac of the eye for 7-10 days.

    Tobrex for children

    Despite the fact that the instructions for the drug indicate that there has been insufficient research on the use of Tobrex in children under 1 year of age, the practical experience of pediatricians indicates the high effectiveness of Tobrex in newborns. Another positive thing is that the effect occurs quickly, without requiring long-term treatment.

    Tobrex for conjunctivitis

    Tobrex for barley

    Tobrex for a runny nose

    Analogues of Tobrex

    Brulamycin, Bramitob, Nembic, Dilaterob, Tobi, Tobracin, Tobrex 2X, Tobracin ADS, Tobropt.

    Levomycetin, Normax, Tsipromed, Oftaquix, Albucid, Floxal, Sulfacyl sodium.

    Reviews about the drug

    Drug price

    Read more:
    Reviews
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    You can add your comments and feedback to this article, subject to the Discussion Rules.

    Source: http://www.tiensmed.ru/news/tobrex-ab1.html

    Tobrex

    Description current as of 05/12/2014

    • Latin name: Tobrex
    • ATX code: S01AA12
    • Active ingredient: Tobramycin
    • Manufacturer: Alcon-Couvreur NVSA; Rijksweg 14, B-2870 Puurs, Belgium

    Compound

    1 ml of solution contains 3 mg of tobramycin as the main substance, and also contains benzalkonium chloride, boric acid, sodium sulfate, sodium hydroxide or sulfuric acid (to stabilize the pH level), tilaxopol, and purified water as excipients.

    Release form

    Available in the form of a transparent, colorless or straw-colored solution in Drop Tanner dropper bottles of 5 ml with the possibility of dosing. 1 bottle in a cardboard box.

    pharmachologic effect

    Tobramycin is an antibiotic that acts on a wide range of pathogens and belongs to the group of aminoglycosides. At low concentrations, a bacteriostatic effect is manifested (inhibits the 30S ribosomal subunit and suspends protein synthesis); at high concentrations, a bactericidal effect is more pronounced (changes the permeability of cell membranes, causing cytolysis).

    Antibacterial activity is high against: Staphylococcus spp. (including Staphylococcus epidermidis, Staphylococcus aureus and their penicillin-producing, coagulase-negative and coagulase-positive strains), Streptococcus spp. (including beta-hemolytic strains of group "A", some non-hemolytic strains, Streptococcus pneumoniae), Enterococcus spp., Escherichia coli, Proteus spp. (including Proteus vulgaris, Proteus mirabilis, indole-positive and indole-negative strains), Serratia spp., Enterobacter spp. (Enterobacter aerogenes), Providencia spp., Citrobacter spp., Haemophilus aegyptius, Morganella morganii, Acinetobacter calcoaceticus (Herellea vaginacola), Moraxella lacunata, some representatives of Neisseria spp. (including Neisseria gonorrhoeae).

    Tobramycin is similar in spectrum of action to gentamicin, but the former is more active against gentamicin-resistant strains and can be used as a drug of choice when neomycin-containing eye drops are ineffective.

    Tobramycin is highly effective against infections caused by Pseudomonas aeruginosa.

    Tobramycin has low effectiveness against most strains of streptococci belonging to group D.

    Pharmacodynamics and pharmacokinetics

    Absorption into the systemic circulation is practically absent if the drug is applied topically.

    Indications for use

    Eye drops, like Tobrex eye ointment, are used to treat infectious and inflammatory lesions of the eye and surrounding tissues:

    The use of Tobrex for barley (meibomitis) and the prevention of complications before and after ophthalmological interventions is also justified.

    Contraindications

    Individual hypersensitivity to the drug and its components.

    Side effects of Tobrex

    In 1.5% of cases, allergic reactions were detected, manifested by itching, lacrimation, and redness of the conjunctiva.

    In 1% of cases, swelling and redness of the eyelids, swelling of the conjunctiva, and discomfort in the eye area were detected.

    In less than 1% of cases, chemosis (swelling of the conjunctiva), blepharitis (inflammation of the edges of the eyelids), keratitis (inflammation of the cornea), eye pain, and isolated ulcerations were detected.

    With long-term treatment, fungal superinfection may occur.

    Instructions for use (Method and dosage)

    The instructions for Tobrex eye drops and the instructions for Tobrex 2x eye drops differ in the frequency of administration of the drug: the first recommends instilling 1 drop 4-5 times a day, the second advises using 1 drop 2-3 times a day; Tobrex ointment is applied in a 1 cm column 2 times a day.

    The difference between Tobrex and Tobrex 2x in the frequency of use is due to the thicker consistency of the latter drug. This feature allows the active substance to remain in the conjunctival sac longer and, therefore, reduce the frequency of drug administration without compromising the therapeutic effect. The course of treatment is 7-10 days.

    In special cases, it is possible to practice instillation every hour, however, after the severity of symptoms has subsided, it is necessary to return to the above-mentioned regimen. At night, it is recommended to supplement treatment with Tobrex ointment to prolong contact with the drug.

    Overdose

    The characteristics of this drug do not suggest the appearance of any symptoms of poisoning when used correctly, or when the contents of one bottle are accidentally ingested.

    Complaints in case of drug overdose may be similar to the side effects observed in some patients (pinpoint keratitis, increased lacrimation, redness, swelling and itching of the eyelids).

    If an overdose of Tobrex does occur during topical use, it is recommended to rinse the eye with warm water.

    Interaction

    It is necessary to exclude the combined use of Tobrex with the following drugs:

    Also, the simultaneous use of Tobrex with drugs containing tetracycline (due to the content of tyloxapol in the former) should not be allowed.

    Terms of sale

    In Russia, Tobrex is available without a prescription, in Ukraine only by prescription.

    Storage conditions

    Store out of the reach of children and away from light at a temperature of °C; an open bottle must be used within 30 days.

    Best before date

    3 years, provided the packaging is sealed.

    special instructions

    An unreasonable increase in the frequency of dosing and duration of use of the drug can lead to the appearance of microorganisms that are insensitive to the components of the drug, including fungal infections of the eye. If symptoms of superinfection appear, it is recommended to consult a doctor.

    Analogues of Tobrex

    Tobrex 2x, Tobrosopt and Tobrimed are complete analogues of Tobrex in release form and composition. From 51 to 34 hryvnia - this is the price in Ukraine for these analogues of eye drops, but in Russia it ranges from 126 to 221 rubles.

    Tobrex for children

    Instructions for children for taking Tobrex eye drops indicate that the drug can be used in pediatric practice in children aged 1 year and older in adult dosages. Studies confirm that the use of the drug is safe and effective in children, as well as newborns suffering from conjunctivitis, who were prescribed five times daily dosing of the drug for a week.

    Tobrex for newborns

    The instructions indicate that Tobrex can be used as eye drops for newborns strictly as prescribed by a doctor. When taken by newborns, the reviews are positive and there is no data indicating a side effect of the drug if the dosage and frequency of administration are observed.

    With antibiotics

    The interaction of Tobrex with other antibiotics is described above (see Interaction).

    During pregnancy and lactation

    The limited amount of data on the use of topical tobramycin in pregnant women does not allow conclusions to be drawn about the reproductive toxicity of the drug. It is recommended to refrain from using the drug during pregnancy.

    There are no studies confirming that tobramycin passes into breast milk, but a risk to a breast-feeding baby cannot be ruled out. It is necessary to make a choice between the possibility of abstaining from breastfeeding during the period of treatment with Tobrex and refusing drug therapy, taking into account the positive effect of breastfeeding for the baby and of using the drug for a nursing mother.

    Reviews for Tobrex

    Numerous reviews of Tobrex eye drops indicate the speed of therapeutic action. Also, according to patients, these eye drops have an extremely small number of side effects or cases of lack of effect from therapy. There is evidence of the effective use of Tobrex as nasal drops for children suffering from rhinitis.

    Price for Tobrex, where to buy

    The Russian price of Tobrex eye drops, as well as the price of the ointment of the same name, does not differ from that in Ukraine. In general, the price of drops in Russia varies around rubles, the price of ointment is about 190 rubles; in Ukraine, the price tag for these drugs averages from 49 to 64 UAH.

    • Online pharmacies in Russia Russia
    • Online pharmacies in Ukraine Ukraine
    • Online pharmacies in Kazakhstan Kazakhstan

    WER.RU

    ZdravZone

    Pharmacy IFC

    Pharmacy24

    PaniPharmacy

    BIOSPHERE

    Education: Graduated from Vitebsk State Medical University with a degree in Surgery. At the university he headed the Council of the Student Scientific Society. Advanced training in 2010 - in the specialty "Oncology" and in 2011 - in the specialty "Mammology, visual forms of oncology".

    Work experience: Worked in a general medical network for 3 years as a surgeon (Vitebsk Emergency Hospital, Liozno Central District Hospital) and part-time as a district oncologist and traumatologist. Worked as a pharmaceutical representative for a year at the Rubicon company.

    Presented 3 rationalization proposals on the topic “Optimization of antibiotic therapy depending on the species composition of microflora”, 2 works took prizes in the republican competition-review of student scientific works (categories 1 and 3).

    Question: Can I use drops after replacing lenses?

    Konstantin: What I liked about the drug Prostanorm: reasonable price, pronounced effect of taking it.

    Valentina: I, too, am all about diet and exercise. I hoped for loads, I thought that my healthy lifestyle.

    Nina: I was on pills for a year and a half, then somehow everything calmed down. Mostly climatefit.

    Elena: With the onset of menopause, the skin completely deteriorated and became dry. I saw a cream for .

    All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

    The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

    Source: http://medside.ru/tobreks

    Tobrex drops - instructions for use

    Tobrex drops instructions

    The instructions for Torbex drops are intended for the patient to familiarize himself with information about the drug before using it for his treatment.

    Form, composition, packaging

    Tobrex drug is eye drops, the solution of which is colorless or slightly yellowish.

    The active component of the drug is tobramycin in the concentration required for the solution. It is supplemented in the composition of the medication with the necessary proportions of purified water, benzalkonium chloride, sulfuric acid or sodium hydroxide, which ensures the pH level, boric acid, tyloxapol and sodium sulfate.

    A dropper bottle with a volume of five milliliters made of plastic has a dispenser and is placed in a cardboard package.

    Storage period and conditions

    The acceptable temperature for keeping drops in storage is from 8 to 30 degrees. Unopened packaging can be stored for up to three years, and after opening for no more than one month. Children should not be allowed near the storage area of ​​the drug.

    Pharmacology

    Tobrex is a broad-spectrum antibiotic. It is related to drugs of the aminoglycoside group. In small concentrations the drug has a bacteriostatic effect on the body, and in higher concentrations it has a bactericidal effect.

    Pharmacokinetics

    Drops have low systemic absorption when applied topically.

    Tobrex indications for use

    The medication is prescribed for those patients who need to prevent complications in the postoperative period of ophthalmological operations. The use of Tobrex is also indicated in the treatment of:

    Contraindications

    Tobrex drops have practically no contraindications, with the exception of a high degree of sensitivity to the substances included in its composition.

    Tobrex instructions for use

    When the infectious process is mild, drops are prescribed to be instilled into the affected eye, one or two at a time, with an interval of four hours.

    If the infection develops in an acute, severe form, it is recommended to instill eye drops every thirty minutes or an hour until the inflammatory process decreases.

    Tobrex drops for children

    Tobrex drops for children have no experience in use. Therefore, their prescription to a child can be carried out in extreme exceptional cases, where more benefits are expected than the development of side effects.

    Tobrex during pregnancy

    Tobrex is not recommended for use during pregnancy due to lack of experience in use for this category of patients. Its use is recommended only as a last resort, when there is an emergency in treating a woman who is expecting or breastfeeding.

    Tobrex for runny nose

    Torbex drops for a runny nose can be used in the treatment of diseases where there is thick purulent discharge from the nose. Can be used for both adult patients and children.

    Side effects

    The manifestation of the side effect of Tobrex can be expressed by an allergic reaction, in the form of swelling of the eyelids accompanied by itching or hyperemia of the conjunctiva.

    Overdose

    Treatment of drug overdose is reduced to symptomatic therapy. Signs of this condition may include the development of erythema, punctate keratitis, and possibly lacrimation and swelling of the eyelids accompanied by itching.

    Drug interactions

    When the recommended combination of Tobrex drops with drugs of the aminoglycoside group is carried out, one should take into account the possibility of a systemic side effect, as well as its intensification, which can be expressed as ototoxicity, nephrotoxicity or disturbance of mineral metabolism.

    Additional instructions

    It must be taken into account that with prolonged treatment with an antibiotic, the growth of fungi and pathogenic microorganisms that are resistant to the drug may increase.

    Contact lenses should not be worn during treatment.

    Due to temporary impairment of visual clarity during treatment, it is not recommended to drive or operate machinery.

    Tobrex analogues

    Torbex has a number of structural analogues: Tobi, Brulamycin, Tobropt, Dilaterob Bramitob, Nembits, Tobrex 2X, Tobracin, Tobracin ADS.

    The drug also has analogues for its effect on the body: Albucid, Levomycetin, Oftaquix, Tsipromed, Floxal, Normax, Sulfacyl sodium.

    Tobrex price

    The cost of the drug Tobrex ranges from 190 to 270 rubles.

    Tobrex reviews

    Patients speak of Tobrex drops mainly as an effective drug for inflammation in the eye area. It is considered a modern and effective medicine, which is very convenient for self-use, since the bottle has a dispenser.

    There are a lot of reviews and all of them, it must be said, are quite similar, so we will give one of them, which can express the opinion of many.

    Maria Visterova: For an unknown reason, my eye became inflamed with swelling of the eyelids, lacrimation and pus in its corner, and not being able to quickly get to a doctor, I consulted a pharmacist at the pharmacy about treatment. After examining my illness, I was advised Tobrex drops. After reading the instructions, I began treatment. The drops do not cause discomfort and are easy to use. Almost on the third day I got rid of this trouble. The medicine is a little expensive, but it helps quickly and effectively.

    Source: http://nasmork-rinit.com/meditsinskie-preparaty/432-tobreks-kapli-instruktsiya-po-primeneniyu

    Tobrex eye drops: instructions for use for newborns and children over one year old, analogues of the drug

    Inflammatory eye diseases in children are quite common. If we are talking about infants, then the list of drugs that can be used to treat a particular condition is reduced. Eye diseases caused by bacteria respond well to treatment with special drops, such as Tobrex. We will look at how to use this drug, what its features are and whether there are any contraindications in this article.

    Active ingredient and principle of operation

    Tobrex drops are an antibiotic, that is, they inhibit the vital activity of certain types of bacteria. The active ingredient of the drug, Tobramycin, belongs to the group of aminoglycosides. Despite the fact that this antibiotic has a broad spectrum of action, it works most effectively against the following types of bacteria that cause ophthalmic diseases:

    Tobramycin may not cope with other types of microorganisms. The instructions indicate that treatment with the drug will not bring results if the disease is caused by anaerobic bacteria or chlamydia. Enterococcus responds to treatment with Tobrex very mediocre.

    This local antibiotic is well and completely excreted in the urine without changes. The manufacturer notes that the effect of Tobramycin on the body is negligible. In addition, the dosage of the active substance in the drug is gentle - only 3%. Thanks to the listed properties, Tobrex is indicated for use in children from birth. The doctor must only determine the required duration of treatment.

    Release form

    Tobrex is available in the form of drops, as well as an ointment - it should be white or cream in color. The ointment is applied to the inner surface of the eyelid in the form of a strip. Due to its thick texture, the drug retains its bactericidal effect longer, however, this form is used mainly for adults. A combination of ointment and drops is possible.

    Tobrex drops are produced in plastic dropper bottles with a volume of 5 ml. This amount of solution is quite enough for a course of treatment. The solution is transparent and may have a slightly yellowish tint. In addition to tobramycin, the solution contains excipients: boric acid, sodium sulfate, sodium hydroxide, etc.

    Tobrex 2X drops are also on sale. This drug is almost the same in composition as its analogue, but has a thicker consistency. This is due to the presence of xanth gum among the ingredients of the drug. Thanks to this component, the medication stays in the conjunctival sac longer and has time to work more effectively. In this case, the dose of Tobrex 2X drops should be reduced by 2 times compared to regular Tobrex.

    Indications for use

    Treatment of ophthalmological diseases in children under one year of age should be supervised by a doctor. Tobrex for children is prescribed if the child is diagnosed with:

    • dacryocystitis is a common disorder in newborns caused by blockage of the lacrimal canal;
    • endophthalmitis – when the membranes inside the eyeball become inflamed;
    • inflammation of the cornea of ​​the eye, called keratitis, as well as keratoconjunctivitis;
    • disease of the area of ​​the eyelid where eyelashes grow - blepharitis;
    • barley is a well-known disease of the follicle or sebaceous gland, which manifests itself in the form of a purulent, inflamed “grain”;
    • conjunctivitis is an inflammation of the upper layer of the eye - the conjunctiva, which is manifested by redness of the white, as well as purulent discharge.

    These drops are also indicated for use after ophthalmological operations. In this case, their task is to prevent inflammation from occurring in the operated area.

    Tobrex is not prescribed for viral ophthalmic infections. However, bacterial, viral or allergic conjunctivitis, in the eyes of the average person, differs little. In this regard, a doctor must make a diagnosis and prescribe treatment as well. Moreover, many pediatricians insist on conducting laboratory tests that show how sensitive the pathogen is to a certain group of antibiotics. This procedure is relevant for newborns, since such babies are treated with a very limited range of drugs. Similar analysis:

    • will allow the doctor to prescribe effective therapy;
    • will make it possible to avoid taking medications that will not bring benefit;
    • will eliminate the possibility of microorganisms becoming resistant to antibiotics.

    Instructions for use

    The instructions for the drug indicate that Tobrex should not be used for more than 7 days. Otherwise, there is a risk of superinfection, which is much more difficult to cure. Superinfection occurs quite often during antibiotic treatment. In different cases, the doctor prescribes a different treatment regimen. How many drops can a baby give?

    To treat conjunctivitis, the drug should be instilled 1-2 drops into each eye, slightly moving the lower eyelid. If the inflammatory process is uncomplicated, you need to instill 2 drops into each eye, once every four hours. In the acute phase of the disease, it is recommended to instill eye drops more often - once an hour.

    When treating infants, you must strictly adhere to the instructions given by the doctor.

    During the treatment of barley, usually the treatment regimen is designed so that the intensity of the effect of the antibiotic gradually decreases. For example, the first two days the eye should be instilled 5 times a day, then 4 times, 3 – and so on until the barley is ripe. However, in each specific case, the doctor may suggest a different treatment plan, depending on the age of the child and the intensity of the inflammatory process.

    How to put eye drops correctly?

    Despite the fact that the eye drop procedure is simple, it should be performed according to the rules. The sequence of actions should be like this:

    • First you need to wash your hands;
    • Shake the bottle with the drug;
    • put the baby on his back;
    • pull down the lower eyelid;
    • turn the bottle upside down;
    • apply eye drops without touching the tip to the mucous membrane;
    • close your eyes, then lightly massage your eyelid and blot off any excess medication with a napkin.

    After use, the bottle should be closed and stored out of reach of the baby. The drug is suitable for use within 30 days after opening.

    Side effects

    The drug may have side effects, but they are rare. There are cases where patients complained of swelling of the eyelids and excessive lacrimation after using drops. Very rarely, situations arise when a patient develops multiple ulcers on the surface of the eyeball. All such manifestations are caused by individual intolerance to one or more components of the solution or allergies.

    Tobrex for runny nose

    Sometimes pediatricians recommend putting eye drops into the nose. This is due to the fact that these drugs dry out the mucous membrane that lines the nasal passages. Most often, Tobrex (or analogues) is prescribed if a child has green snot and a runny nose that does not go away for more than 7 days. As a rule, sinusitis, sinusitis, and sinusitis are treated in this way. This rhinitis is bacterial in nature, and topical antibiotics are ideal to combat it.

    However, to achieve maximum effect, before instilling Tobrex into your nose, you should rinse your nasal passages with saline solution. Then clear the nose of mucus using an aspirator if the baby cannot blow his nose on his own.

    Analogues of the drug

    Tobrex is a fairly effective drug, but other drugs are also used to treat newborns and older children. Let's look at analogues of the drug, which ones are cheaper, as well as their features.

    Tobrex has several analogues, among which you can choose the appropriate treatment option

    There are also almost complete analogues of Tobrex, the active substance of which is identical. These include Brulamycin, Nebcin, Tobi, Dilaterol.

    Washing your eyes with home remedies has a good effect. To do this, you need to moisten a cotton pad in the prepared broth and rinse the eye, starting from the outer corner to the inner. You can use:

    • Black tea;
    • green tea (without additives or flavorings);
    • camomile tea;
    • furatsilin (dissolve 1 tablet in ½ cup of boiled water).

    If a child's eye turns sour, you should definitely show it to the pediatrician. Perhaps the problem will be solved quickly if treatment is started immediately. However, you should not prescribe any drops to your child yourself, especially if it is an infant.

    We cured stye with Tobrex. Our daughter somehow woke up with a reddened eyelid. At first we didn’t pay attention, but the redness increased every day. We took her to the ophthalmologist - it turned out it was stye. As soon as they started dripping Tobrex, the grain ripened, then it burst. So , works.

    Attention! All information on the site is provided for informational purposes only and is for informational purposes only. For all questions regarding the diagnosis and treatment of diseases, you must consult a doctor for an in-person consultation.

    Source: http://vseprorebenka.ru/zdorove/preparaty/tobreks-glaznye-kapli-instrukciya-dlya-detej.html

    TOBREX

    Broad-spectrum aminoglycoside antibiotic. It has a bactericidal effect, disrupting protein synthesis and the permeability of the cytoplasmic membrane of bacteria.

    Highly active against Pseudomonas aeruginosa.

    Tobramycin is active against gram-negative bacteria: Escherichia coli, Proteus spp. (indole-positive and indole-negative strains), Klebsiella spp., Serratia spp., Providencia spp., Enterobacter spp., Shigella spp., Salmonella spp., Citrobacter spp., Haemophilus influenzae; gram-positive bacteria: Staphylococcus spp. (including strains producing penicillinase).

    Inactive against Streptococcus spp. (including Enterococcus spp.).

    For systemic use: severe infectious and inflammatory diseases caused by pathogens sensitive to tobramycin (sepsis, meningitis, peritonitis, endocarditis, respiratory tract infections, skin and soft tissue infections, urinary tract infections, bone tissue infections).

    For topical use: eye infections (as part of combination therapy).

    Individual, depending on the indications, severity of the disease, and patient’s age.

    Administer intramuscularly or intravenously. Used externally and locally in appropriate dosage forms.

    From the central nervous system and peripheral nervous system: ototoxic effect, headache, lethargy, disorientation, impaired neuromuscular transmission.

    From the digestive system: nausea, vomiting, increased levels of liver transaminases and bilirubin in the blood.

    From the hematopoietic system: anemia, granulocytopenia, thrombocytopenia.

    Local reactions: pain at the injection site.

    Metabolism: hypocalcemia, hyponatremia, hypokalemia, hypomagnesemia.

    Other: possible nephrotoxic effect, allergic reactions.

    To ask a question about the project or contact the editors, use this form.

    Source: http://health.mail.ru/drug/tobrex/

    Tobrex eye drops for children and adults - instructions for use, price

    Tobrex eye drops are an effective antibacterial drug used in ophthalmology. Intended for the treatment of eye diseases in adults and children. This drug is used even in newborns, since it does not have a negative effect on the baby’s body. Tobrex is well tolerated by patients and causes virtually no side effects.

    Tobrex eye drops - description

    Photo: Tobrex drops

    Tobrex is a drug with a wide spectrum of antibacterial action. The active substance of the drug, tobramycin, belongs to the class of aminoglycosides and acts in two directions. In low concentrations it provides a bacteriostatic effect (disrupts protein synthesis in the cells of pathogenic microorganisms), in high concentrations it exhibits a bactericidal effect (destroys cytoplasmic membranes and causes the death of microbial cells).

    Tobramycin is active against a number of pathogenic microflora; the active substance has a detrimental effect on Proteus, Escherichia coli, staphylococci and streptococci, Klebsiella, gonococci, enterobacteria and other microorganisms.

    In terms of the spectrum of antimicrobial action, the drug is very similar to gentamicin, but exhibits higher activity against those strains of bacteria that are insensitive to this antibiotic. Therefore, Tobrex is often prescribed as a replacement when gentamicin-based drugs are ineffective. At the same time, tobramycin is insufficiently effective against strains of streptococci belonging to group D.

    Tobrex eye drops are intended for topical use, so the active substance is practically not absorbed into the bloodstream. This explains the safety of the drug, the minimum number of contraindications to its use and the absence of side effects.

    Composition, release forms

    Tobrex eye drops are a transparent, colorless, or slightly straw-colored, odorless solution. 1 ml of solution contains 3 mg of the active substance - tobramycin + auxiliary components (boric acid, sodium hydroxide, sodium sulfate, etc.). Drops are produced in convenient bottles - droppers with a volume of 5 ml, made of low-density polyethylene.

    In pharmacies, in addition to this form of the drug, you can find Tobrex 2X eye drops. The composition of these products, indications, contraindications and principles of action are generally identical. The only difference is that Tobrex 2X drops can be instilled less frequently (2-3 times a day). This is explained by the thicker consistency of the drug, which is provided by an auxiliary component such as xanth gum. This substance helps maintain the concentration of the active substance and allows it to remain in the conjunctival sac longer. Accordingly, the frequency of use of the drug is reduced without compromising the therapeutic result.

    When are Tobrex drops prescribed?

    Instructions for use of Tobrex indicate that eye drops are intended for the treatment of infectious and inflammatory lesions of the eyes and periorbital area. The main indications for use of the drug are the following conditions:

    1. conjunctivitis (inflammation of the mucous membrane of the eyes);
    2. blepharitis (inflammation of the eyelids);
    3. keratoconjunctivitis;
    4. blepharoconjunctivitis;
    5. keratitis (inflammation of the cornea of ​​the eyes);
    6. iridocyclitis (inflammation of the iris);
    7. endophthalmitis (purulent damage to the inner lining of the eyeball).

    It is advisable to use eye drops for meibomitis or, in other words, barley (purulent inflammation of the eyelids). Eye drops can be used not only for their intended purpose, but also used for instillation into the nose. This use of the drug is possible for sinusitis and sinusitis, when thick, purulent discharge forms in the nose. In this case, Tobrex drops help to avoid complications and quickly destroy pathogenic microorganisms.

    In addition, in ophthalmology, Tobrex drops are additionally used for prophylactic purposes in the postoperative period. Their use helps prevent the development of infectious complications.

    Contraindications

    In grateful reviews of Tobrex, patients say that the drug is very well tolerated and does not have a negative effect on the body. When applied topically, the active substance does not penetrate the bloodstream, and therefore systemic reactions from internal organs do not occur. Tobrex is one of the few drugs that has virtually no contraindications for use. The only limitation is individual intolerance to the components that make up the medication.

    Instructions for use

    Tobrex eye drops are intended for topical use. They are used according to the following scheme:

    • When treating uncomplicated infectious processes, the instructions for the drug recommend instilling 1-2 drops of solution into the conjunctival sac every 4 hours.
    • When treating acute manifestations of severe infections, the solution should be instilled every minute. The standard single dose is 2 drops in each eye. As the severity of inflammatory reactions decreases, the frequency of instillations should be gradually reduced, increasing the time intervals between procedures.

    The attending physician should prescribe the drug after clarifying the diagnosis and taking into account the severity of the symptoms of the ophthalmological disease.

    How to properly perform eye treatment?

    There is nothing complicated in using Tobrex drops, you just need to follow a certain procedure:

    • Before treating your eyes, wash your hands thoroughly with soap and water.
    • Remove the bottle of drops from the packaging and shake vigorously several times.
    • Open the bottle by removing the cap,
    • Tilt your head back and pull down your lower eyelid.
    • Turn the bottle over and hold it in an upright position, without touching the tip to the eyelids and mucous membranes of the eyes.
    • Lightly press the bottle with your fingers and gently drop 1-2 drops of the solution into the conjunctival sac.
    • Close your eyelids, lightly press your finger on the inner corner of your eye, and make several massaging movements.
    • Gently blot off excess solution with a cotton pad.

    Repeat the procedure for the other eye in the same order, then close and put away the bottle with the drug.

    If during the procedure you accidentally exceed the dose of the drug, there is nothing wrong with that. You need to rinse your eyes with warm water and repeat the treatment. After opening the bottle, the drug should be used within a month. The drops should be stored in a dark place at a temperature not exceeding 25 °C.

    Tobrex eye drops for children are used as prescribed by a doctor and in the recommended dosage. The standard treatment regimen for children over one year old involves using the solution five times a day. During each procedure, no more than 1 drop of solution should be instilled into the baby’s eyes. The course of treatment cannot exceed 7 days.

    Tobrex is highly effective in newborns. In pediatric practice, the drug is used to treat various inflammatory processes and infectious eye diseases in infants in the first months of life. The use of Tobrex helps to successfully fight conjunctivitis, inflammation in the lacrimal sac, blockage of the nasolacrimal duct and other abnormalities. Antibacterial drops can be used in infants for no more than 7 days.

    The drug Tobrex 2X is used for similar indications, but it is instilled less frequently - 1-2 drops 2-3 times a day. The optimal scheme for using the solution should be determined by the attending physician.

    Side effects

    Adverse reactions with the use of the drug rarely develop. They occur mainly in people with hypersensitivity and a tendency to allergic reactions and are manifested by lacrimation, redness and swelling of the conjunctiva, and itching. In this case, treatment with the drug is stopped and consultation with an ophthalmologist is sought to adjust subsequent treatment.

    In case of accidental overdose, symptoms such as profuse lacrimation, punctate keratitis, severe itching and swelling of the eyelids were noted. In isolated cases, patients complained of pain in the eyes and the appearance of small ulcers on the cornea. In case of overdose of the drug, it is recommended to rinse your eyes with warm water and consult a specialist. If necessary, the doctor will prescribe symptomatic treatment.

    Additional recommendations

    There is no clear opinion among experts about the possibility of using antibacterial drops during pregnancy and lactation. Doctors prescribe Tobrex drops for this category of patients only when the expected benefit from using the drug is higher than the potential risk of adverse reactions. The systemic effect of the active substance, tobramycin, in the drops is very insignificant, which means that the likelihood of a negative effect on the body of a pregnant woman and unborn child is minimal.

    Soft lenses should not be worn during treatment with Tobrex. If it is impossible to do without them, then before the procedure the lenses must be removed and then put on no earlier than 15 minutes after eye treatment.

    Remember that long-term use of antibacterial drops is unjustified; regular use of the drug for 24 days or more can lead to a decrease in its effectiveness and the appearance of pathogenic microorganisms that are insensitive to the action of the active substance. Therefore, in cases where the desired therapeutic effect cannot be achieved, it is recommended to do a laboratory test (culture) before and after treatment.

    Tobrex drops should not be prescribed simultaneously with antibiotics from the aminoglycoside group, since such a combination can lead to increased systemic side effects and provoke complications such as hearing loss, toxic effects on the kidneys, and disruption of hematopoietic processes.

    After the instillation procedure, blurred vision sometimes occurs, so it is not recommended to drive a vehicle or work on potentially dangerous equipment for half an hour.

    Analogs

    If necessary, Tobrex drops can be replaced with structural analogues containing the same active substance. The list of such drugs includes:

    If you are intolerant to tobramycin, your doctor may prescribe medications that contain a different active substance but provide an identical therapeutic effect. These are medications such as Albucid, Normax, Tsipromed, Levomycetin, Floxal. The selection of the necessary medication should be carried out by an ophthalmologist; you should not change the drug yourself, as this can lead to unpredictable consequences for eye health.

    In the pharmacy chain, the cost of the medicine varies depending on the form of release, the manufacturer and the pharmacists’ markup. On average, the price of Tobrex is about 200 rubles; Tobrex 2X eye drops are slightly cheaper - from 170 rubles per pack.

    Reviews about the use of Tobrex are overwhelmingly positive. Patients note a good therapeutic effect even after a short course of using antibacterial drops. The drug quickly stops the inflammatory process, eliminates unpleasant symptoms (itching, irritation, lacrimation, swelling) and speeds up recovery.

    The use of the drug in pediatric practice deserves special mention. The main advantage of Tobrex is safety and the absence of side effects. This allows it to be used to treat newborns and infants and achieve a lasting therapeutic effect in various ophthalmological pathologies.

    Reviews about the application

    Tobrex eye drops are very good for conjunctivitis. I often encounter this problem. Previously, I was treated with Albucid, but when using it, my eyes began to sting severely. The doctor advised me to try these drops, I bought the drug and I really liked its effect. Tobrex relieves all symptoms of conjunctivitis very quickly, without any discomfort. After instillation, the eyes do not burn; on the contrary, relief immediately sets in, itching, irritation, redness go away, and lacrimation stops. Usually, five days of using the drug is enough for me to cope with conjunctivitis and eliminate unpleasant symptoms.

    Review #2

    Recently my daughter came home from kindergarten with red eyes; they thought she had rubbed it or got dust. They washed her eyes, but the baby continued to rub them with her hands. The next morning she could barely open her eyelids, purulent discharge appeared, her eyes were swollen and red. At an appointment with an ophthalmologist, it turned out that it was conjunctivitis. The doctor prescribed Tobrex 2X drops for us and said that this is a strong drug and we only need to drip it 2-3 times a day. The medicine is quite inexpensive, there are also simple Tobrex drops, but the pharmacist explained that they need to be instilled more often, almost every hour. It took us only three days to eliminate all the symptoms. Tobrex is a very strong remedy and, most importantly, safe, since the treatment went smoothly and there were no side effects.

    Review #3

    I suffer from hay fever and every year when certain plants bloom, I suffer from allergy symptoms. Along with a runny nose, sneezing, and headache, signs of allergic conjunctivitis appear: the eyes become red, swollen, itchy, and tears flow constantly. I take certain antihistamines and also put Tobrex in my eyes. This is a very good drug that quickly relieves all inflammatory manifestations. In the first days you can use it every hour, and then less often. But usually a week of treatment is enough for everything to return to normal.

    Review #4

    My child was prescribed Tobrex eye drops while still in the maternity hospital. The baby had some kind of inflammatory process in the lacrimal canal. The medicine was instilled into the eyes twice a day. In the first days, my son’s tears flowed constantly, but after 2 days everything stopped. We used this medicine for about 5 days in total. I was worried, but the pediatrician explained that it would not do any harm. The active substance of Tobrex does not penetrate the blood, it acts only at the local level, so it cannot harm the baby in any way.

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    Before using medications, consult your doctor!

    Source: http://glavvrach.com/glaznye-kapli-tobreks/

    Tobrex: instructions for use

    Compound

    Tobramycin - 3 mg.

    Benzalkonium chloride, boric acid, sodium sulfate anhydrous, sodium chloride, tilaxopol, sulfuric acid and/or sodium hydroxide qs to adjust pH, purified water.

    Description

    pharmachologic effect

    Highly active against the following susceptible strains:

    — Staphylococcus spp., including Staphylococcus aureus and Staphylococcus epidermidis (coagulase-negative and coagulase-positive), including strains resistant to penicillin.

    - Streptococcus spp., including some groups - a-p-hemolytic species, some non-hemolytic species and Streptococcus pneumoniae.

    — Pseudomonas Aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis (indole-negative) and indole-positive species of Proteus, Haemophilus influenzae and H.aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus (Herellea vaginacola) and some species of Neisseria (including including Neisseria gonorrhoeae).

    Pharmacokinetics

    Indications for use

    Prevention of postoperative infectious complications in ophthalmology.

    Contraindications

    Pregnancy and lactation

    Clinical studies have shown that tobramycin is safe and effective for use in children.

    Directions for use and doses

    How to instill the drug correctly.

    • Wash your hands thoroughly before instillation.

    • Tilt your head back. Pull your lower eyelid down and look up. Place 1¬2 drops into the space between the eyelid and the eyeball. Do not touch the tip of the bottle to your eyelids, eyelashes, or touch it with your hands.

    • Close your eye and pat it dry with a cotton swab.

    • Without opening your eyes, lightly press the inner corner of your eyes for 2 minutes. This will improve the effectiveness of the drops.

    • The bottle must be tightly closed after each use.

    Side effect

    an allergic reaction accompanied by itching and swelling of the eyelids, as well as conjunctival hyperemia.

    Overdose

    Interaction with other drugs

    Features of application

    Wearing contact lenses during treatment with the drug is unacceptable.

    Patients who temporarily lose clarity of vision after instillation of the drug are not recommended to drive a car or work with complex machinery, machines or any other complex equipment that requires clarity of vision.

    Release form

    Storage conditions

    Best before date

    Conditions for dispensing from pharmacies

    You should consult your doctor and read the instructions before use.

    Source: http://apteka.103.by/tobreks-instruktsiya/

    Tobrex for a runny nose

    Tobrex eye drops

    Inflammatory eye diseases of an infectious nature can be caused not by one type of bacteria, but by a combination of several types. In such cases, it is advisable to use broad-spectrum topical antibiotics, one of which is Tobrex eye drops. This drug is able to quickly relieve the inflammatory process and does not require long treatment courses.

    Tobrex eye drops for conjunctivitis - composition and application

    The active component of this medication is tobramycin, its concentration is 3 mg per 1 ml of medicinal solution. The substance belongs to the group of aminoglycoside antibiotics. The spectrum of action against gram-positive and gram-negative microorganisms is quite wide:

    • staphylococci;
    • coli;
    • streptococci (except type D);
    • Klebsiella;
    • Pseudomonas aeruginosa;
    • enterobacter.

    In addition to tobramycin, drops contain boric acid, sodium hydroxide and sulfate, tilaxopol, purified water and the preservative benzalkonium chloride.

    Tobrex eye drops are used for barley, as well as in the treatment of pathogenic bacterial inflammatory processes:

    The usual scheme of use involves injecting the solution into the conjunctival sac twice a day, 1 drop. If the course of the disease has become acutely inflammatory, Tobrex can be used every 60 minutes, after which the frequency of instillations should be reduced to 4 times a day, and then switch to the usual treatment regimen. The full course of therapy should not exceed 1 week, since the bacteria that caused the disease may become resistant to the antibiotic.

    Although Tobrex has no other contraindications other than hypersensitivity to the ingredients of the drops, it can lead to the following side effects:

    • redness, irritation of the eyes;
    • swelling of the mucous membranes;
    • corneal ulceration;
    • Pain in the eyes.

    It should be noted that the drug can be used even during pregnancy, lactation and for newborns.

    Eye drops for runny nose

    Can eye drops be used for a runny nose?

    A runny nose is an inflammatory process on the nasal mucosa. As with any disease, the manifestations of a runny nose depend on the trigger mechanism, the stage of its progression and the triggering factors. During the cold season, colds and runny nose await us at every turn. At the first signs of illness, we want to restore damaged health as soon as possible. We all know that some medications can be used for off-label purposes, and they have proven themselves to be excellent for this purpose. Sometimes, to treat a runny nose, you can use medications that at first glance are not suitable for this purpose, for example, eye drops. The attending physician may prescribe them for purulent bacterial rhinitis. although this is not stated in any of the medical instructions and recommendations.

    The antiseptic contained in the drops helps get rid of the infection. But not everyone considers this the correct treatment, since it is almost impossible to calculate the dose required to completely destroy microbes. In addition, with such treatment, the risk of microbial resistance to the components of the drug is too high, which means that the disease may drag on or become chronic. However, for certain types of runny nose, eye drops can effectively treat it.

    What eye drops can be used to treat a runny nose?

    Most often, drops with antiseptics and antibiotics are prescribed. There are practically no similar nasal drops with antibiotics, and those that are on pharmacy shelves do not always work. Putting antibiotics into your nose is not recommended as it can cause serious harm to your health.

    How to use Tobrex eye drops for babies?

    When a small child’s eyes become numb and watery, and after sleep the eyelashes stick together, experienced mothers remember the tea they drank, and young parents begin to panic. Most likely, nothing terrible is happening, but in children under one year old, any diseases should not be treated on their own, especially in premature babies. Turning to the pediatrician, the mother will hear one of two diagnoses:

    • Blockage of the tear duct (dacryocystitis);
    • Bacterial conjunctivitis.

    In both cases, the pediatric ophthalmologist will prescribe Tobrex antibacterial eye drops to the newborn. In the first case, it will be additional or preventive, and in the second, it will be the main treatment. It can also be prescribed after an eye injury to prevent infection.

    The active ingredient in Tobrex eye drops is the antibiotic tobramycin, which, as doctors say, has a wide spectrum of action. This means that it equally effectively fights several types of microorganisms: Staphylococcus aureus, Streptococcus, Pseudomonas aeruginosa, Klebsiella, Enterobacteriaceae and other pathogenic bacteria. They are the ones who most often cause conjunctivitis in infants and provoke inflammation in dacryocystitis.

    In some cases, Tobrex is also used for instillation into the nose, if a runny nose is caused by pathogenic bacteria, and nasal discharge has become thick and purulent. This happens when the maxillary sinuses (sinusitis) or sinuses (frontitis) in a newborn become inflamed. The drug is dosed in the same way as for traditional ophthalmic use.

    Tobrex - instructions for use, analogues, reviews, price

    Tobrex eye drops

    The antibiotic from the aminoglycoside group, Tobramycin, which is part of Tobrex, has a detrimental effect on streptococci. staphylococci. Proteus, Escherichia coli. Klebsiella, enterobacteria, acinetobacter, diphtheria bacteria. gonococci and other microbes.

    Release forms

    Tobrex is available as eye drops and eye ointment.

    • Eye drops. 0.3% solution 5 ml in a sterile plastic dropper bottle.

    1 ml of solution contains Tobramycin 3 mg and excipients.

  • Eye ointment 0.3%, 3.5 g in an aluminum tube.

    • Instructions for use of Tobrex eye drops

    Indications for use

    • Русский
    • Conjunctivitis (inflammation of the mucous membrane of the eye);
    • keratoconjunctivitis;
    • keratitis (inflammation of the cornea);
    • blepharoconjunctivitis;
    • blepharitis (inflammation of the edges of the eyelids);
    • dacryocystitis (inflammation of the lacrimal sac);
    • iridocyclitis (inflammation of the iris and ciliary body of the eyeball);
    • endophthalmitis (purulent inflammation of the inner membranes of the eyeball);
    • meibomitis (inflammation of the sebaceous glands of the eyelids).

    Tobrex is effective in treating these diseases if they are caused by bacteria sensitive to Tobramycin.

    Tobrex can also be used for prophylactic purposes (to prevent the development of infections after operations) in ophthalmology.

    Contraindications

    Individual intolerance to any of the components of the drug.

    Side effects

    Some patients may experience redness of the conjunctiva, itching and swelling of the eyelids. In rare cases, there is pain in the eyes and the appearance of ulcers on the cornea.

    Long-term use of Tobrex (over 24 days) may be accompanied by increased growth of microorganisms and fungi insensitive to Tobramycin.

    Tobrex drops - instructions for use

    Tobrex drops instructions

    The instructions for Torbex drops are intended for the patient to familiarize himself with information about the drug before using it for his treatment.

    Form, composition, packaging

    Tobrex drug is eye drops, the solution of which is colorless or slightly yellowish.

    The active component of the drug is tobramycin in the concentration required for the solution. It is supplemented in the composition of the medication with the necessary proportions of purified water, benzalkonium chloride, sulfuric acid or sodium hydroxide, which ensures the pH level, boric acid, tyloxapol and sodium sulfate.

    A dropper bottle with a volume of five milliliters made of plastic has a dispenser and is placed in a cardboard package.

    Storage period and conditions

    The acceptable temperature for keeping drops in storage is from 8 to 30 degrees. Unopened packaging can be stored for up to three years, and after opening for no more than one month. Children should not be allowed near the storage area of ​​the drug.

    Pharmacology

    Tobrex is a broad-spectrum antibiotic. It is related to drugs of the aminoglycoside group. In small concentrations the drug has a bacteriostatic effect on the body, and in higher concentrations it has a bactericidal effect.

    Pharmacokinetics

    Drops have low systemic absorption when applied topically.

    Tobrex indications for use

    The medication is prescribed for those patients who need to prevent complications in the postoperative period of ophthalmological operations. The use of Tobrex is also indicated in the treatment of:

    Contraindications

    Tobrex drops have practically no contraindications, with the exception of a high degree of sensitivity to the substances included in its composition.

    Source: http://prostudahelp.ru/post/13087-tobreks_pri_nasmorke