Tizin xylo instructions for use during pregnancy

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Tizin Xylo - vasoconstrictor drops for runny nose, rhinitis, sinusitis and sinusitis.

Acute and chronic runny nose, as well as their complications in the form of sinusitis of various localizations (sinusitis and frontal sinusitis), with a prolonged course, sharply worsen a person’s quality of life and can be accompanied by otitis, laryngitis and bronchitis, as well as inflammatory processes of the brain and its membranes.

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With reduced immunity, these diseases become recurrent and difficult to treat with conventional methods.

Before you continue reading: If you are looking for an effective method of getting rid of a runny nose, pharyngitis, tonsillitis, bronchitis or colds, then be sure to look at this section of the site after reading this article. This information has helped so many people, we hope it will help you too! So, now back to the article.

One of the most effective and safe medications - Tizin Xylo (spray or nasal drops) - a drug from the group of alpha-adrenergic stimulants, helps to get rid of the disease and prevent complications. Alpha adrenergic stimulants are substances that increase the activity of adrenaline receptors. As a result, characteristic effects are observed: in particular, the tone of smooth muscles increases, including the muscles of the walls of blood vessels, while they spasm.

Due to the activation of adrenergic receptors, Tizin drops have a pronounced therapeutic effect for rhinitis (as a runny nose is called in medical terminology), including its allergic forms, accompanied by swelling of the nasopharyngeal mucosa and difficulty breathing. The latter conditions are extremely difficult to tolerate and, as a rule, are protracted.

According to the instructions, Tizin Xylo can be used to treat adults and children, starting from infancy. The spray and drops are low-toxic, and their therapeutic effect is fast and lasting. Compared to nasal drops of the previous generation, this medicine wins in all respects. The best evidence of the effectiveness of Tizin is patient reviews and enormous popularity among doctors of various specializations: therapists, pediatricians, allergists and otorhinolaryngologists.

Tizin Xylo for infants and older children varies in concentration, which should always be indicated in the price list along with the price of the drug. Tizin for children under 7 years of age is produced in a lower percentage dosage, so when purchasing you should pay special attention to this indicator.

Composition and pharmacological action of Tizin Xylo

The pharmacological action of the drug Tizin in the instructions for use is explained by its chemical structure and group affiliation.

The active substance - tetrizoline hydrochloride - belongs to alpha-adrenergic stimulants and provides a rapid and lasting vasoconstrictor effect. As a result, instillation or injection of the drug into the nasal cavity leads to a reduction in swelling of the mucous membrane, freeing up the nasal passages and normalizing breathing. Both spray and Tizin drops act almost instantly, and the resulting effect lasts for several hours. Like all long-term nasal medications, this drug contains excipients - preservatives, etc. As such, benzalkonium chloride, benzyl alcohol and disodium edetate are added to the composition.

Spray Tizin

A nasal spray is a liquid dosage form that is administered into the nasal sinuses using a special dispenser. Like other nasal sprays, Tizin spray is available in a bottle with a spray dispenser. Prescribed for children over 6 years of age and adults. It has a quick and lasting effect and is used for treatment and diagnosis. For children in this form the drug is available as a 0.05% solution, for adults – 0.1%.

It should be remembered that Tizin in the form of a spray should not be used for a long time, or more often than indicated in the instructions or recommended by a doctor. Otherwise, especially with long-term use, the development of side effects is possible (see below). Usually the spray is prescribed in short courses, no more than 4 times a day (one injection into each nasal passage). If for some reason long-term therapy is necessary, for older children and adults it is recommended to use the drug in the form of a gel (such Tizin also exists): it irritates the mucous membrane less and does not lead to drying out.

Nasal drops

Tizin nasal drops, like the medicine in the form of a spray, are available for adults and children in dosages similar to those indicated above, in bottles with a special dropper. For young children, nasal drops are easier and safer than using a spray or gel. Therefore, the drug is prescribed to children under 6 years of age in drops, 1-2 in each nasal passage, no more than three times a day. The medicine is not indicated for long-term use in young children. If treatment is delayed, the drops are replaced with gel (for older children and adults).

Tizin Xylo and indications for use

The highly effective and low-toxicity Tizin Xylo can be prescribed both for the treatment of a number of diseases and for preparing the patient for diagnostic studies involving certain medical manipulations in the nasal cavity.

Allergists everywhere prescribe Tizin for the treatment of acute rhinitis of allergic origin. The medicine is also widely used for acute respiratory infections accompanied by a runny nose. The pediatric form of the drug is indicated for otitis media. In this case, its use helps not only to reduce swelling of the nasopharyngeal mucosa: in children, the passages between the maxillary sinuses and the middle ear cavity are short and wide, and therefore Tizin Xylo penetrates directly to the site of inflammation, relieving swelling and relieving pressure on the eardrum.

Tizin is also recommended for preparing adult patients with suspected sinusitis or an established diagnosis for therapeutic and diagnostic puncture of the maxillary sinus: reducing swelling allows the doctor to easily insert the necessary instruments into the nasal passage.

In addition, Tizin is used for children in the treatment of various hay fever. At the same time, it allows you to significantly reduce the duration of therapy and significantly improves the standard of living of patients. The drug is recommended not only as a means for premedication preparation for surgery, but also for drug therapy of sinusitis or sinusitis of other localization.

Orientation, side effects and overdose

Depending on the dosage form and dosage of Tizin Xylo, the price may vary slightly. Although some prefer to choose the most cost-effective option, when purchasing drops or spray, you need to focus not on the price, but on the diagnosis (ARD or acute allergic rhinitis, sinusitis, otitis media, etc.) and the age of the patient.

When used according to instructions, Tizin has virtually no adverse reactions. The main thing is to strictly follow the treatment regimen and its duration. The high effectiveness of the drug allows you not to think about the duration of treatment for uncomplicated acute respiratory infections. However, the effect in the treatment of persistent hay fever and sinusitis may not be so quick.

If the recommended duration of therapy and the frequency of instillation/injection are exceeded, Tizin can cause irritation of the nasal mucosa: it becomes excessively dry, resulting in injury due to high/low temperatures, mechanical and other effects. In this case, patients experience burning and tingling in the nasal cavity, they are bothered by sneezing, and increased secretion of fluid.

In rare cases and, above all, with an overdose of the drug, swelling of the nasal mucosa can progress, and the patient’s condition can worsen, accompanied by tachycardia, heart rhythm disturbances, and increased blood pressure.

According to reviews, patients who used Tizin uncontrollably were bothered by intoxication symptoms: headache, blurred vision, nausea and vomiting, insomnia. These phenomena did not require urgent measures and, as a rule, disappeared on their own when treatment was discontinued.

With long-term therapy in high dosages, Tizin can provoke the development of depression. Therefore, patients with a tendency towards depressive disorders should be prescribed this medicine with a certain degree of caution.

Restrictions and contraindications for the use of Tizin during pregnancy and in some other cases

The main problems when taking the medicine arise in patients who have not carefully read the instructions or who have not paid attention to the restrictions and contraindications.

Tizin Xylo is very popular among adult patients who have experienced the obvious benefits of the drug. The demand for medicine is especially high in the off-season, when unstable weather and an abundance of viruses lead to an increase in the incidence of acute respiratory infections.

If the rules of use are followed, children's Tizin is not only effective, but also safe, and therefore in half a percent concentration it is very often used in pediatrics, starting from infancy. Allergists universally recommend this medication for both adults and children during an exacerbation of seasonal runny nose - hay fever.

However, like all medicines, Tizin, including children's, has restrictions on its use, as well as contraindications that you should be aware of.

These include individual intolerance to any of the components of the drug and a tendency to tachycardia. In adults - a severe form of atherosclerosis, the presence of glaucoma or atrophic rhinitis.

Tizin is not prescribed during pregnancy, hyperthyroidism, or if there is a history of surgical neurosurgical interventions. These contraindications are typical for all alpha-agonists. It is the stimulation of alpha-adrenergic receptors that imposes restrictions on the prescription of this drug to pregnant women: the drug is not suitable for use during pregnancy due to its ability to increase the tone of the smooth muscle muscles of the uterus. At the same time, it contracts, which can lead to miscarriage. But even if a miscarriage does not occur, the embryo inside the uterus with increased tone suffers from hypoxia and may not develop properly. Therefore, Tizin Xylo is completely contraindicated during pregnancy in the first and second trimester.

But if necessary, it can be recommended to nursing mothers, albeit with a certain degree of caution, in low concentrations and always under the supervision of the child’s condition by a pediatrician.

Instead of Tizin Xylo, other modern drugs can be successfully used during pregnancy. This, first of all, includes medicines based on natural herbs, hypoallergenic and not having any negative effect on the mother and fetus. If absolutely necessary, Tizin during late pregnancy can be prescribed with great caution in the form of drops. In this case, you should use a pediatric dosage and concentration and constantly monitor the condition of the patient and the fetus.

If children's Tizin is prescribed to children under two years of age, the child's condition during treatment should also be assessed by the attending physician.

It is recommended to avoid using this medicine in gel form in children under 7 years of age.

Chronic rhinitis is not a contraindication for the use of Tizin, but in this case it cannot be used for a long time. If colds are accompanied by the formation of crusts in the nose, the instructions recommend replacing the spray with a gel.

Interaction of Tizin with other drugs

The medicine is well compatible with most oral medications, but there are some exceptions. According to the instructions, Tizin for adults and children cannot be used together with MAO inhibitors and drugs from a number of tricyclic antidepressants.

Price category, holiday conditions and storage

The cost of this drug allows it to be prescribed without regard to the material wealth of any family: also because the courses of treatment are short and the consumption of the drug is low. The price of Tizin may vary depending on the form, percentage of active ingredient and markups of intermediaries. Due to its low toxicity, you can buy the medicine without a doctor's prescription. The drug can be stored for up to 3 years at room temperature.

Price range

The average price for Tizin for children 0.05% is 70 - 95 rubles;

adult 0.1%, Tizin BIO SPRAY – 170 – 200 rubles.

The article above and comments written by readers are for informational purposes only and do not encourage self-medication. Consult a specialist regarding your own symptoms and illnesses. When taking any medicine, you should always use the instructions that come with the medicine and your doctor's advice as a guide.

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Tizin during pregnancy: can the drug be used?

To figure out whether it is acceptable for an expectant mother to use Tizin, you need to take a closer look at its characteristics.

Is Tizin dangerous while pregnant?

According to the official instructions, pregnancy is not an absolute contraindication to the use of this drug. However, these drops are an option when more gentle treatment methods have exhausted themselves and have not brought the desired effect.

Taking Tizin during pregnancy is dangerous not for the pregnant woman herself, but for the fetus. Self-administration of drops is unacceptable. To avoid adverse consequences, you should definitely consult your doctor. He will help you choose an effective and safest treatment regimen.

Spray or drops?

The Tizin trademark combines a whole line of drugs for the treatment of rhinitis, differing in composition, dosage and release form. To determine which medicine is more effective, you should consider each representative in detail.

It is believed that using a spray is the safest. When using Tizin in the form of drops, problems may arise with dosing, flow of the drug into the nasopharynx and its subsequent ingestion (which is extremely undesirable). Currently, the release of Tizin in this form has been discontinued.

Using the spray is convenient and safe: the required amount of the drug corresponds to the number of presses on the dispenser.

Composition of Tizin

Tizin is not just vasoconstrictor drops and sprays, united by a common composition and mechanism of action. Depending on what goals are pursued in the treatment of a particular runny nose, the drug is selected according to the active and auxiliary components.

Tizin drops

The release form in the form of drops includes a 0.1% solution of tetrizoline hydrochloride and a set of additional substances. The children's version consists of the same components, but in a lower dosage of the main substance - 0.05%. Bottle volume – 10 ml.

Spray Tizin Xylo

The effect of this spray is due to the content of xylometazoline hydrochloride. The percentage is identical to drops: 0.1% solution for adults and 0.05% for children.

It is believed that the use of drops in pediatric dosage is one of the safest ways to use Tizin. But you shouldn't believe this. The introduction of any volume of the drug with some probability can lead to undesirable consequences.

Spray Tizin Xylo Bio

The composition and quantitative content of the main active ingredient is similar to the previous representative. A distinctive feature is that hyaluronic acid is added to Tizin Xylo Bio. It’s not for nothing that the manufacturers decided to include it in the drug: this component protects the mucous membrane from drying out, softens it and, therefore, promotes speedy healing.

Spray Tizin Alergy

Effectively used for runny nose caused by allergies. This is explained by its composition: Tizin Alergy contains levocabastine hydrochloride (540 mcg per 1 ml).

Effect of the drug

The main mechanism of action that unites all representatives of the Tizin Xylo line is a vasoconstrictor effect. Tetrizoline hydrochloride and xylometazoline hydrochloride are substances that excite alpha-adrenergic receptors, located, among other things, in the nasal mucosa. Activation of these receptors serves as a kind of “signal” for the immediate narrowing of small arteries in the nasal passages. This leads to a significant reduction in inflammatory edema.

Tizin Xylo has a pronounced local effect on the nasal mucosa within 1-2 minutes after application. The duration of action is from 4 to 8 hours, which allows you to use the drops not too often.

Tizin Alergy spray has a slightly different mechanism of operation. When an allergen enters the body, specific biologically active substances are produced that irritate histamine receptors and also trigger a cascade of immune reactions. Due to this pathological process, swelling of the nasal mucosa occurs and copious mucous discharge appears.

The levocabastine hydrochloride contained in the drug is a blocker of the “culprits” for the occurrence of allergy symptoms - H1-histamine receptors, disrupting the cascade of reactions at an early level.

Indications

Tizin Xylo spray is used not only for therapeutic purposes, but also as part of preparatory therapy before diagnostic procedures.

The main list of indications includes:

  1. Rhinitis and pharyngitis in acute respiratory diseases. Tizin helps reduce mucus secretion, restoring normal nasal breathing.
  2. Otitis media Thanks to the action of the active substance, swelling of the mucous membrane is reduced, the patency of the Eustachian tube is restored and, consequently, the pressure on the eardrum is reduced.
  3. Sinusitis (frontal sinusitis, sinusitis) in combination with the main therapy.
  4. Preparation for diagnostic and therapeutic procedures. Inflamed, edematous mucosa can interfere with rhinoscopic examination and the introduction of the necessary instruments during puncture of the maxillary sinus. Tizin Xylo causes constriction of the arterioles, thereby restoring air flow in the nose.
  5. Hay fever (a disease of an allergic nature associated with seasonal flowering of plants, manifested by severe rhinitis with copious mucous discharge).

Tizin Xylo Alergy has a different mechanism of action from xylometazoline and is used exclusively for rhinitis of an allergic nature.

Contraindications

Despite the fact that the sprays of the Tizin line (Xylo and Xylo Bio) are topical preparations that do not have strong toxicity or other negative effects, they must be treated with caution. Can Tizin be used by all patients? No.

  • Hypersensitivity to active components (for Tizin Alergy this is the only existing obstacle to use).
  • Dry rhinitis (inflammation may increase due to additional drying of the nasal mucosa).
  • Age under 2 years (any dosage starting from 0.05% is prohibited).
  • Age less than 6 years (0.1% sprays are not allowed, but 0.05% are allowed).

The list of relative contraindications to the use of Tizin is much wider. The use of a spray in this case is not prohibited, but requires special attention and consultation with your doctor. A comparison of possible risks and benefits will be needed for many chronic diseases.

  1. Various types of cardiovascular pathology (coronary heart disease, including severe arrhythmia, arterial hypertension, vascular and cardiac aneurysm).
  2. Benign tumor of the adrenal gland (pheochromocytoma).
  3. Metabolic diseases in the stage of sub- and decompensation (diabetes mellitus, hyperthyroidism).
  4. Taking medications that increase blood pressure (citramon, some antidepressants and other drugs);

A special FDA system has been developed to assess the degree of risk to the pregnant woman and fetus when using medications. According to this scale, the drugs in the Tizin line belong to category C. This means that proper clinical studies have not been conducted for ethical reasons, and there is no reliable data on a pronounced negative effect on the health of mother and child.

Therefore, the use of the drug Tizin Xylo during pregnancy is permissible, but only if the benefits of its use significantly outweigh the risk of negative effects.

Breastfeeding is also not an absolute contraindication to the use of Tizin Xylo, Xylo Bio and Allergy. However, strict adherence to the instructions is required.

Rules of application

Let's look at the basic recommendations for using Tizin during pregnancy.

In 1st trimester

The first trimester is the stage at which the fertilized egg is fixed in the uterine cavity, as well as the first formation of organs and systems of the unborn child. This is a period when the slightest external influence can lead to the termination of pregnancy or the beginning of abnormal development of the fetus.

Xylometazoline causes local activation of adrenoreceptors in the mucous membrane of the nasal passages, however, accidental entry (by ingestion) of the drug into the systemic circulation can also lead to uterine hypertonicity.

This effect is fraught with premature expulsion of the fetus. When this undesirable effect occurs in the 1st trimester of pregnancy, there is a risk of spontaneous miscarriage. Is it worth using Tizin during pregnancy in this case? The 1st trimester is too dangerous for this.

If allergic rhinitis occurs, then after a preliminary discussion with your doctor, you can take Tizin Alergy. Application regimen: 2 doses in each nasal passage up to 3-4 times a day. The course of treatment should not exceed 5 days.

In the 2nd trimester

The use of Tizin in the 2nd trimester is possible, but also only after consulting a doctor. The dosage will directly depend on the level of individual sensitivity to the drug. If the doctor has chosen Tizin, he is interested in prescribing the smallest volume of the drug.

The maximum amount of time during which it is permissible to use the spray is 5 days. Failure to comply with this rule is fraught with the risk of addiction to xylometazoline: the nasal mucosa will constantly swell, regardless of the presence or absence of rhinitis, returning to its previous state only after repeated use of the drug.

As the instructions say, the frequency of use of the drug should not exceed 3 times a day. To avoid adverse effects as much as possible, pregnant women are recommended to prescribe drugs from the Tizin line once a day. The optimal regimen for use: injecting the drug at night before bedtime and replacing it during the day with rinsing the nasal passages with a water-salt solution.

In the 3rd trimester

At this stage, the fetus is almost formed, and the woman’s body gradually begins to prepare for childbirth. The use of Tizin Xylo and Tizin Xylo Bio may lead to a premature start of this process. It is strongly recommended to avoid using these vasoconstrictor drops.

Features of using drops during pregnancy

If Tizin is the drug of choice, the instructions for use during pregnancy will have some peculiarities.

Considering that the use of Tizin is fraught with negative effects on the fetus, its use must meet a number of requirements:

  • prescribing the lowest possible dose of medication if it is not possible to replace it;
  • rapid discontinuation of the drug upon signs of recovery;
  • immediate refusal of Tizin if there is a threat to the health of the pregnant woman and fetus;
  • avoiding accidental ingestion of the drug during use so that xylometazoline cannot be absorbed into the blood through the stomach.

Side effects

Even if you follow the instructions for use, you may encounter unwanted reactions from the body.

  • the occurrence of allergies;
  • the appearance of nausea;
  • dizziness, drowsiness, headache due to a sharp spasm of cerebral vessels;
  • burning sensation, dryness at the site of application of the drug;
  • pain in the nasopharynx.

Analogues safe for pregnant women

Sprays Tizin Xylo and Tizin Xlio Bio are not first-line drugs for the treatment of acute rhinitis in pregnant women. In order to get rid of a runny nose without the risk of harming the fetus, there are many alternative options.

  1. Sprays based on sea water. These drugs work due to the fact that the liquid accumulated in the nasal mucosa rushes for the salt ions contained in the medicine. This helps relieve inflammatory swelling. Representatives of this group include Aqualor, Aqua Maris, Marimer.
  2. Saline. Contains salt, like seawater-based sprays, but in a lower concentration (0.9%), optimal for the body. It does not cause drying out of the mucous membrane and is used to rinse the nasal passages.
  3. Oil-based drops (for example, Pinosol). Suitable for dry rhinitis. They have an anti-inflammatory, moisturizing effect on the nasal mucosa.

Can Tizin be used during pregnancy? The answer to the question cannot be called unambiguous. Although this drug is considered effective and has low toxicity, there is a risk of harm to the fetus. When using xylometazoline, undesirable consequences do not always occur, but it is worth weighing the pros and cons.

However, refusing to treat rhinitis, which is harmless at first glance, is associated with great danger: with difficulty in nasal breathing, hypoxia occurs in the mother’s body, and the unborn child may also begin to lack oxygen. The best way out of this situation is to contact your doctor. It is he who will help the patient choose exactly the drug that will be as safe as possible and at the same time effective.

Source: http://moylor.ru/lekarstva/tizin-pri-beremennosti/

Tizin during pregnancy: benefit or unjustified risk?

There is often debate among expectant mothers about whether it is permissible to use vasoconstrictors, including Tizin, during pregnancy. For an ordinary person, a runny nose does not cause as much trouble as for a woman carrying a child, because it is often unacceptable to use even the most banal, seemingly, means to relieve nasal congestion, because the medicine can harm the unborn baby.

Any medication is always accompanied by instructions for use, including Tizin. However, in order not to harm herself and the child, a pregnant woman should use common sense and not neglect the advice of a doctor. To understand whether Tizin is suitable for pregnant women, you should familiarize yourself with the main characteristics of the drug.

Effect of the drug and composition

Tizin Xylo and Xylo Bio drops contain the adrenergic agonist xylometazoline, which has a tonic effect on blood vessels. The substance helps to narrow them, which leads to a decrease in the secretion of mucous secretion. During pregnancy, the use of such drugs may be risky due to spastic contractions of the uterus.

In addition to the above chemical compound, Xylo Bio spray is also enriched with hyaluronic acid.

Due to the combination of these components, the drug has the following effects:

  • moisturizes mucous membranes;
  • the removal of crusts from the nasal passages is facilitated;
  • has a tonic effect on blood vessels;
  • eliminates swelling and hyperemia of the internal lining of the nasal concha;
  • promotes the regeneration of damage to the mucous membrane.

Tizin spray, which contains an antiallergic component, should also be taken with extreme caution during pregnancy. Tizin Alergy has a completely different active substance, however, due to the fact that drug safety tests are not carried out on pregnant women and children, it cannot be said that a solution with levocabastine hydrochloride is safe for pregnant women.

Can it be used during pregnancy?

Before you start treatment with Tizin, you must carefully study its instructions for use, especially during pregnancy.

The use of the drug in this period has its own characteristics:

  • If it is impossible to replace the medicine with another drug, then it is necessary to instill a minimum amount of solution in an effective dosage into the nose.
  • When recovery occurs, you should stop using Tizin.
  • Treatment with the drug should be discontinued if a threat of miscarriage develops.
  • Try to avoid swallowing the solution so that the active substance does not enter the systemic circulation.

To understand the question of whether anyone, including children's Tizin, can be used to relieve nasal congestion during pregnancy, you should know what happens to the body of the mother and child at different stages of fetal formation.

In 1st trimester

The first trimester is the time when the fertilized egg is strengthened in the uterus and all the major systems and organs of the unborn baby are formed. The use of inappropriate substances during this period of pregnancy can lead to various disorders. The fact is that the placenta has not yet formed, one of the functions of which is to protect the child from the negative effects of medications. Therefore, medications can easily penetrate from the mother’s bloodstream to the baby and cause serious changes in the growing body.

Xylometazoline has an effect on adrenergic receptors of the nasal mucosa, but if the drug is accidentally swallowed, the substance enters the blood and can cause uterine hypertonicity.

So is it possible to drip Tizin into the nose during pregnancy in the 1st trimester? This can be very risky and can lead to miscarriage. If rhinitis is of allergic etiology, then after consultation with a doctor, it is allowed to use Tizin Alergy according to the following scheme: 2 injections into each nasal concha up to 4 times a day.

In the 2nd trimester

Tizin during pregnancy in the 2nd trimester can be used to treat a runny nose, but only as prescribed by a doctor. The period from 13 to 24 weeks is considered the safest during the entire period of intrauterine development of a child.

If a doctor prescribes Tizin for children during pregnancy as a medicine, the duration of its use should not exceed 5 days, since longer use can cause addiction to the drug. This is manifested by the fact that the mucous membrane of the nasal passages will be constantly swollen, regardless of whether there is a runny nose or not, and will return to normal only after irrigation with the drug.

In the 3rd trimester

When choosing Tizin to eliminate rhinitis during pregnancy in the 3rd trimester, you need to understand that at this stage the formation of the fetus is completed, and the child is preparing for birth. The drops have a vasoconstrictor effect, so their administration can provoke premature onset of labor.

In the last weeks of pregnancy, it is better to give preference to products that do not contain xylometazoline and other substances that affect vascular tone.

Indications and contraindications

Tizin nasal spray is used in the following cases:

  • Runny nose and pharyngitis that occur against the background of ARVI. The use of Tizin allows you to reduce the amount of mucus secreted, which helps restore full nasal breathing.
  • Sinusitis of the maxillary or frontal sinus. Prescribed as part of complex treatment.
  • Inflammation of the middle ear. Xylometazoline helps reduce mucus secretion, thereby restoring the patency of the Eustachian tube and reducing pressure on the eardrum.
  • Preparation for diagnosing the nasal cavity. A swollen mucous membrane can make it difficult to conduct an instrumental examination (rhinoscopy), so before the procedure, the doctor often prescribes Tizin drops into the nose.
  • Allergic rhinitis. To eliminate allergy symptoms, Tizin Alergy is used, which has a fundamentally different mechanism of action, unlike drops with xylometazoline.

Before starting to use the nasal spray, you should consult your gynecologist to see if it is possible to be treated with Tizin during pregnancy in a particular case. In some situations, the use of cold drops containing xylometazoline is unacceptable.

The drug Tizin has the following contraindications during pregnancy:

  • a history of an allergic reaction to one of the components of the drug;
  • atrophic and dry rhinitis.

The spray should be used with extreme caution for the following diseases, which can be considered relative contraindications to the use of the product:

  • Pathology of the heart and blood vessels - coronary heart disease, severe arterial hypertension, aneurysms of large vessels.
  • Pheochromocytoma.
  • Metabolic diseases that are at the subcompensation stage, such as type 2 diabetes mellitus or hyperthyroidism.

Tizin Xylo

The principle of action of Tizin Xylo nasal drops is based on the vasoconstrictor effect of the active substance, which is xylometazoline hydrochloride, therefore during pregnancy it is necessary to consult a doctor before starting use.

Available in two dosages:

  • 0.05% for children from 2 to 6 years old;
  • 0.1% for adults and children over 6 years of age.

It is children's Tizin, according to the instructions for use, that is safer, so if there is a need to treat a runny nose with this drug during pregnancy, then it is better to give preference to a spray with a concentration of the active component of 0.05%.

Tizin Xylo Bio

The composition of the drug Tizin Xylo Bio is similar to the previous drug, so during pregnancy you should also be careful about its use. The concentration of xylometazoline is the same, the difference is that the drug contains hyaluronic acid. This component protects the inner lining of the nose from drying out, has a moisturizing effect on the mucous membrane, and accelerates the regeneration of damaged tissues.

Tizin Xylo Bio with xylometazoline during pregnancy is used in cases where the therapeutic effectiveness outweighs the potential risk to the fetus.

Tizin Alerji

The drug is used to treat allergies of various etiologies. The active ingredient in nasal drops is levocabastine hydrochloride. The manufacturer does not guarantee the complete safety of Tizin Alergy for use during pregnancy, since tests have not been carried out on women bearing a child.

Instructions

The annotation for the drug contains the manufacturer's recommendations for use during pregnancy:

  • You can irrigate the nasal passages no more than 3, maximum 4 times a day. While carrying a baby, doctors advise limiting it to single use at night. Congestion usually worsens during sleep, so it is recommended to use saline solutions during the day to flush out accumulated mucus from the nasal passages.
  • The duration of treatment should not exceed 5 days to avoid the development of addiction.
  • If longer therapy is necessary, a break should be taken to avoid mucosal atrophy.

Side effects

Even the use of Tizin, strictly regulated by the instructions, to eliminate the symptoms of rhinitis during pregnancy can cause side effects.

Possible consequences of treatment with nasal drops may include the following conditions:

  • development of hypersensitivity reaction;
  • the occurrence of dyspeptic disorders (nausea, vomiting);
  • drowsiness, headaches and dizziness that appear due to rapidly increasing vascular spasm;
  • a feeling of dryness and burning of the nasal mucous membranes;
  • soreness in the nasopharynx.

Analogues safe for pregnant women

Tizin Xylo and Xylo Bio, as indicated in the instructions, can be used during pregnancy only if treatment with other drugs is impossible and the risk to the mother from a possible complication of the disease exceeds the likelihood of a risk to the intrauterine development of the fetus.

For the treatment of rhinitis, there are other medications that are better to give preference, since they do not harm the development of the child:

  • Preparations containing sterilized sea water. Such agents act due to the fact that the saline solution flushes out accumulations of mucus from the nasal cavity, and also helps to reduce its secretion. Medicinal solutions include AquaMaris, Aqualor, Marimer.
  • Oil-based products. Recommended for dry runny nose, as they well moisturize the mucous membrane, eliminate dryness and remove signs of inflammation in the nasal cavity. Such a drug is Pinosol.
  • Physiological isotonic solution. It is an aqueous solution containing sodium chloride at a concentration of 0.9%, which corresponds to the salt content in blood plasma. Used to rinse the nasal passages. It does not have a negative effect on the body, it is allowed for regular use, as it is not addictive.

Is it possible to use Tizin for nasal congestion during pregnancy? It is impossible to say for sure, since this issue is decided individually by the attending physician. The drug effectively copes with the symptoms of rhinitis, has low toxicity, but there is a risk of uterine hypertonicity, which can negatively affect the condition of the fetus, and in the early period can lead to termination of pregnancy. Treatment with drugs containing xylometazoline is not always accompanied by complications, therefore, together with the doctor, it is necessary to evaluate all the positive and negative aspects of such therapy and make a decision.

Before starting to use Tizin during pregnancy, the expectant mother should think several times, weigh the pros and cons, and also decide whether the risk arising from treatment with this drug is justified, or whether it is better to give preference another, safer method.

Source: http://mama66.ru/pregn/tizin-pri-beremennosti

Tizin during pregnancy: application features and useful recommendations

Everyone knows that pregnant women have a reduced level of immunity and an increased risk of developing infectious diseases. In addition to viral respiratory infections, allergies can plague pregnant women. The most unpleasant symptom of these diseases is sometimes nasal congestion. However, during these months, the usual medications for the common cold cannot be used without consulting a specialist. Sometimes doctors prescribe Tizin to combat a runny nose, the use of which during pregnancy requires knowledge and compliance with a number of precautions.

Is it possible to use Tizin spray and drops during pregnancy?

The drug Tizin belongs to the group of vasoconstrictors that effectively relieve swelling of the nasal mucosa by narrowing blood vessels. It is believed that the use of such drugs during pregnancy is prohibited or allowed in some cases with extreme caution under strict medical supervision. They can be prescribed to a pregnant woman only if there are no contraindications and the expected benefit to the mother outweighs the risk to the fetus.

The danger is that the medicine can enter the stomach through the nasopharynx, and then be absorbed into the blood and adversely affect the placenta, thereby disrupting the blood supply to the fetus. In the future, this can lead to disruption of the full intrauterine development of the child and even provoke life-threatening hypoxia (acute lack of oxygen).

Tizin is effective for relieving swelling of the nasal mucosa of any origin - infectious diseases, allergic rhinitis. Doctors are of the opinion that it is better to avoid taking the medicine in the 1st and 3rd trimesters, since during these periods the risk of complications increases. In the 2nd trimester, Tizin is used with caution strictly according to indications.

The treatment regimen is prescribed only by the attending physician, based on individual indicators. The expectant mother must abide by it unquestioningly.

The Tizin line of drugs is available in different forms and has different characteristics. Contact a specialist you trust, he will determine which drug from this line to choose and what dosage (for adults - 0.1% or for children - 0.05%) is best to use.

The use of Tizin with a pediatric dosage during pregnancy is safer for expectant mothers, although less effective. Usually they are appointed.

Table: characteristics of Tizin series products and instructions for their use during pregnancy

  • Has a vasoconstrictor effect,
  • improves the discharge of mucous secretions.
  • Has a vasoconstrictor effect,
  • relieves swelling and redness of the mucous membrane,
  • improves nasal breathing,
  • has a moisturizing and regenerating effect on the nasal mucosa.

Photo gallery: Tizin line of drugs available in pediatric and adult dosages

Instructions for safe use

You need to know a number of rules regarding how often and for how long you can use Tizin, so as not to inadvertently cause harm to the baby:

  1. The maximum period of use of the drug is 3–5 days. Longer use leads to the development of side effects. If necessary, the course is repeated after a few days.
  2. Tizin in the form of nasal drops is administered no more than 3 times a day.
  3. The spray is injected up to 4 times a day.

Contraindications and side effects

Before starting to use the medicine, you must carefully study the attached instructions and exclude possible contraindications. It is important to note that for each drug from the Tizin line they are different.

Table: contraindications to the use of Tizin

  • Concomitant use with drugs that increase blood pressure;
  • hypersensitivity to tetrizoline, the active substance.
  • Concomitant use with drugs that increase blood pressure;
  • hypertension;
  • tachycardia;
  • atherosclerosis;
  • angina pectoris;
  • glaucoma;
  • atrophic rhinitis;
  • diabetes;
  • individual intolerance or hypersensitivity to the components of the product.
  • Atrophic rhinitis;
  • thyrotoxicosis;
  • severe diseases of the cardiovascular system (ischemia, angina, hypertension and others);
  • high sensitivity to at least one of the components of the product;
  • increased intracranial pressure;
  • diabetes;
  • hyperthyroidism;
  • combined use with drugs that increase blood pressure.
  • Renal dysfunction;
  • hypersensitivity to the components of the product.

If Tizin is used irrationally or inattentively, a pregnant woman may develop a number of side effects. You should carefully monitor your well-being during treatment and if you notice any unpleasant symptoms, stop using the product and consult a doctor.

Table: possible side effects

  • Headaches, dizziness;
  • weakness and drowsiness, sleep disturbance;
  • nausea;
  • hypertension;
  • hyperglycemia;
  • dry nasal mucosa, burning and tingling sensation, sneezing;
  • allergic reactions.
  • Redness, burning, sneezing, increased secretion;
  • with long-term use, it is possible to develop dry rhinitis with irreversible damage and the formation of crusts on the nasal mucosa and/or drug-induced rhinitis, that is, dependence on this drug;
  • headache, insomnia, fatigue, depression;
  • in very rare cases - tachycardia, increased blood pressure, arrhythmias, visual impairment.
  • Burning sensation, sneezing, increased swelling after discontinuation of the drug;
  • with prolonged use, the development of drug-induced rhinitis, as well as inflammation of the mucous membrane with the formation of crusts, is possible;
  • headache, insomnia, fatigue, depression;
  • increased blood pressure, arrhythmias, tachycardia.
  • Nausea;
  • headaches, drowsiness, dizziness;
  • sore throat, cough;
  • nose bleed;
  • tachycardia;
  • allergic reactions.

For the future baby, taking Tizin without consultation with a specialist can result in serious problems. As mentioned above, if the drug enters the bloodstream, it can affect the thickness of the lumen of the blood vessels of the placenta, which can lead to serious problems in the development of the fetus and even a threat to its life.

How to replace Tizin

There are a number of Tizin analogues that help relieve swelling of the nasal mucosa, which are allowed to be used during pregnancy. Let's look at the most common ones in the table.

Table: vasoconstrictor drugs allowed during pregnancy

  • Drops,
  • spray.
  • Atrophic chronic rhinitis;
  • glaucoma, severe forms of cardiovascular diseases;
  • diabetes;
  • high intraocular pressure;
  • increased sensitivity and intolerance to components;
  • simultaneous use with drugs that increase blood pressure.
  • Acute respiratory diseases accompanied by rhinitis;
  • allergic rhinitis;
  • chronic vasomotor rhinitis.
  • Drops,
  • spray.
  • Phenylephrine;
  • Dimetindene maleate.
  • Atrophic chronic rhinitis;
  • glaucoma;
  • diseases of the cardiovascular system;
  • diabetes;
  • thyroid diseases;
  • increased sensitivity and intolerance to components;
  • simultaneous use with drugs that increase blood pressure.
  • Acute rhinitis (including colds);
  • allergic rhinitis;
  • vasomotor and chronic rhinitis.
  • Arterial hypertension;
  • tachycardia;
  • atherosclerosis;
  • glaucoma;
  • atrophic chronic rhinitis;
  • hyperthyroidism;
  • diabetes;
  • hypersensitivity and intolerance to the components of the drug.
  • Acute respiratory diseases accompanied by rhinitis;
  • allergic rhinitis.
  • Essential oils of eucalyptus, pine, mint;
  • thymol;
  • guaiazulene;
  • alpha tocopherol acetate.
  • Allergic rhinitis;
  • hypersensitivity and intolerance to the components of the drug.
  • Acute rhinitis,
  • atrophic chronic rhinitis.
  • Levomenthol;
  • eucalyptus essential oil.
  • Acute rhinitis;
  • chronic rhinitis.
  • Acute and chronic runny nose caused by an inflammatory process;
  • allergic rhinitis;
  • vasomotor rhinitis.
  • Acute and chronic runny nose caused by an inflammatory process;
  • allergic rhinitis;
  • vasomotor rhinitis.
  • Black mustard;
  • milky juice of milkweed;
  • meadow lumbago;
  • luffa;
  • Mercury iodide.
  • Disorders of the thyroid gland;
  • hypersensitivity and intolerance to the components of the drug.

Photo gallery: Tizin analogues prescribed for pregnant women

Reviews from women

I was first prescribed Tizin for children during pregnancy because my nose was stuffy. Since the usual one is contraindicated during pregnancy, and the dosage is small for children, it is possible. Without any shadow of a doubt, I bought Tizin Xylo for children, because in principle I was familiar with regular Tizin - I had used it before, and it helped me a lot. <…> Tizin Xylo copes with its task perfectly - after 5 minutes the effect begins and the nose breathes, as before. I recommend it if you have problems with congestion, well, of course, after consulting a doctor.

I am now 7 months pregnant. And from the very beginning of pregnancy, my nose was stuffy. That is, there was no runny nose, but it felt as if someone had put a clothespin on his nose. I've tried a lot of things. I started with those that are allowed for pregnant women, but they didn’t help me. I suffered from sleepless nights, breathing through my mouth... but after trying Tizin Xylo Bio, I felt like a human being. One injection into each nostril lasts me 5-6 hours. But Tizin simply dries out the mucous membrane and hypertrophies, as the ENT doctor explained to me. So I recommend Tizin Xylo Bio to everyone for nasal congestion. It's moisturizing! And it's inexpensive!

During pregnancy, I caught a cold and my nose was stuffy. <…> I tried everything, but nothing helped. The nose did not breathe at all for more than a week, headaches began, and from lack of oxygen the baby began to move more actively in the stomach. Then I remembered that during my first pregnancy, the therapist told me that you can use any drops and sprays that are intended for children, without abusing them, and for no more than five days. But for me, even five days was salvation. Then I scoured the entire Internet in search of something more or less safe and found exactly this product, read the composition, instructions and bought it. It penetrates the nose perfectly, two small injections are enough. I timed it, enough for 7-8 hours. So, I sprayed it in the morning and at night.

PS The baby was born absolutely healthy.

With my chronic runny nose, I tried half of the existing drops. I can’t even sleep or go out without drops. I used Tizin for a while, then I began to notice that after using it, blood clots formed in my nose, I thought, I think I stopped using it, and after a while, when using it again, I blew blood from my nose. It was very unpleasant, I won't buy it again. Moreover, during pregnancy, in any case, it had to be changed; it cannot be used.

In general, the spray penetrates the nasal cavity well and does not leak. Has no smell. It relieves swelling, clears the nose well, it’s a pity that it didn’t suit me personally.

I bought these drops for the first time 2 months ago when I had a cold. I had a terrible runny nose, and the doctor advised me to buy antibiotic drops. I bought Tizin Xylo for children, because I thought that they would be more gentle. It pierces the nose well, you wake up in the morning - you can’t breathe, your nose is so clogged, you sniff it - and it immediately feels better. True, the effect only lasts for 2-3 hours, then the nose gets stuffy again. But in almost 3 days I cured my runny nose with Tizin, and the disease did not progress, i.e., no cough or sore throat. And now I’m sitting here, sniffling. Running nose again. From the first day, when I felt an unpleasant tickling in my nose, I immediately started using Tizin. The instructions say to use no more than 3 times a day. I sprayed only in the morning and evening. On the first day everything was fine. But the next day, before going to bed, I sprayed it once into each nostril and felt an unpleasant sensation in my left: burning and tingling. But after 10 minutes it passed, and I calmed down. In the morning, when I woke up, I went to the bathroom to clear my nose, and after that blood gushed out of my left nostril. I wasn’t very scared, because when I lived in the North, this happened often. I treated my nose with peroxide, and it seemed to go away. But after some time, after another attempt to clear my nose, the blood began to bleed again, and this happened every time after blowing my nose. And walking around with a nose full of snot, sorry, is also not a good idea. As a result, my nose bled 10 times during the day. Unpleasant. Now I'm afraid to use Tizin. Therefore, I don’t know whether to recommend it or not; most likely, this is an individual reaction.

Many medications for infectious and allergic rhinitis are prohibited to be used during pregnancy; vasoconstrictor medications can only be used if absolutely necessary. The use of Tizin spray and drops during pregnancy effectively relieves nasal congestion, but should be used with caution. It is important to understand that any medication during pregnancy must be used strictly according to the regimen prescribed by the doctor.

Source: http://babyzzz.ru/pregnancy/13143.html