Tetrizoline eye drops

Active ingredient/beginning: tetrizoline

Berberyl; Burnil; Visine; Visoptic; Diabenyl; (Diabenil-T); Montevisin; Octilia; Tetrizoline; Tizin.

Tetrizoline is an anticongestant; when applied topically, it causes a vasoconstrictor effect.

Table of contents:

A remedy for the treatment of allergic conjunctivitis and rhinitis - relieves itching, burning, swelling and hyperemia.

Tetrizoline

Tetrizoline is an alpha-adrenergic agonist, sympathomimetic, and anticongestant.

Tetrizoline, when applied topically, causes a vasoconstrictor effect that develops within a few minutes and persists for a long time.

Tetrizoline is used conjunctivally and intranasally - it reduces swelling and hyperemia, burning sensation, irritation, itching, soreness of the mucous membrane, lacrimation and runny nose.

The effect develops a few minutes after instillation and lasts 4-8 hours. The effect develops without secondary reactive hyperemia, has no toxic effect and has virtually no effect on eye tissue. When applied topically, Tetrizoline is practically not absorbed.

Indications:

  • irritation, itching, swelling, hyperemia, burning of the conjunctiva of the eyes, lacrimation, injection of the sclera caused by chemical or physical agents (smoke, dust, cosmetics, contact lenses, swimming in chlorinated water, strong lighting); allergic conjunctivitis;
  • swelling of the mucous membrane of the nasal cavity and nasopharynx; allergic rhinitis.

    Directions for use and dosage:

    Individual, depending on the indications and the dosage form used.

    To use eye drops, instill 1-2 drops into each eye 2-3 times a day into the lower conjunctival sac. The maximum duration of continuous use is no more than 4 days. When wearing contact lenses, they are removed before instillation of the drug and installed after 15 minutes.

    For instillation into the nose, a single dose for adults and children over 6 years of age is 2-4 drops in each nasal passage; Children aged 2 to 6 years are prescribed a 0.05% solution of drops, a single drop in each nasal passage. Nasal drops should be used at intervals of at least 3 hours.

    Symptoms: pupil dilation, nausea, cyanosis, fever, convulsions, tachycardia, arrhythmia, cardiac arrest, arterial hypertension, pulmonary edema, impaired respiratory function and mental activity.

    Symptoms usually go away on their own. If necessary, use activated charcoal, gastric lavage, oxygen inhalation, antipyretics and anticonvulsants; to reduce blood pressure, 5 ml of phentolamine in saline solution or 100 mg is slowly administered intravenously.

    Contraindications:

  • hypersensitivity to tetrizoline or to the components of the drug;
  • severe eye diseases (glaucoma, epidermal endothelial corneal dystrophy);
  • children under 3 years of age;
  • simultaneous use of MAO inhibitors.

    Children under 6 years of age are contraindicated in 0.1% nasal drops.

    From the organ of vision: dilated pupils (mydriasis), increased intraocular pressure, reactive hyperemia.

    When using drops in the nose, a burning and tingling sensation in the nose, sneezing, and dryness of the nasal cavity may occur. With prolonged use or exceeding the dose, secondary edema of the nasal mucosa may develop.

    Side effects associated with the systemic effect of the drug: arterial hypertension, cardiac dysfunction, tachycardia, hyperglycemia, headache, dizziness, sleep disturbance, drowsiness, weakness, tremor, nausea.

    Allergic reactions are possible.

    Special instructions and precautions:

    Strictly follow the dosage regimen.

    Despite the low level of systemic absorption, Tetrizoline should be used with caution in patients with arterial hypertension, coronary artery disease, hyperthyroidism, diabetes mellitus, during treatment with antidepressants, during pregnancy, and lactation.

    With long-term use of Tetrizoline in high doses or accidental ingestion, toxic effects may develop.

    Continuous use of eye drops for more than 4 days is not recommended. If symptoms persist or become more severe within 4 days of regular use of Tetrizoline, consultation with an ophthalmologist is necessary. Direct contact with soft contact lenses should be avoided due to possible disruption of their transparency. When driving a car or operating machinery, the possibility of blurred vision should be taken into account.

    The contents of an open bottle should be used within a maximum of 4 weeks.

    Tetrizoline is incompatible with MAO inhibitors.

    At a temperature not exceeding 30 C.

    The expiration date is indicated on the packaging.

    Dispensed from pharmacies - without a doctor's prescription.

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    Instructions for use of drugs, analogues, reviews

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    Tetrizoline*

    PRESCRIPTION MEDICINES ARE PRESCRIBED TO THE PATIENT ONLY BY A DOCTOR. THIS INSTRUCTION IS FOR MEDICAL PROFESSIONALS ONLY.

    Description of the active substance Tetrizoline/Tetryzoline.

    Formula: C13H16N2, chemical name: 4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole (as hydrochloride).

    Pharmacological group: vegetotropic agents/adrenomimetic agents/Alpha-adrenomimetics; organotropic drugs/ophthalmic drugs; organotropic agents/respiratory agents/anticongestants.

    Pharmacological action: anticongestive, vasoconstrictor.

    Pharmacological properties

    Tetrizoline has a stimulating effect on alpha-adrenergic receptors. When used topically in the form of eye drops, it reduces swelling of the conjunctiva, sensations of irritation, burning, soreness, itching of the mucous membrane of the eyes, and reduces lacrimation. When applied topically in the form of nasal drops, it narrows the small arterioles of the nasal passages, reduces secretion and reduces swelling of the nasal mucosa. The effects of tetrizoline develop within a few minutes and last 4 – 8 hours. When used topically, tetrizoline is almost not absorbed.

    Indications

    Nasal drops: swelling of the nasal mucosa in people who suffer from rhinitis, sinusitis, pharyngitis, hay fever; if it is necessary to carry out therapeutic and diagnostic measures to reduce swelling of the nasal mucosa.

    Eye drops: swelling of the conjunctiva, irritation of the conjunctiva (when exposed to physical and chemical factors, including dust, smoke, chlorinated water, cosmetics, bright light, contact lenses), secondary hyperemia in allergic eye diseases, catarrhal conjunctivitis.

    Method of administration of tetrizoline and dose

    Intranasally, patients over 6 years old - 0.1% solution, 2-4 drops, children 2-6 years old - 0.05% solution, 2-3 drops in each nasal passage with an interval of at least 3 hours. Tetrizoline should not be used for more than 3 to 5 days (except on doctor's recommendations). Re-use is possible only after a break of several days.

    Conjunctivally, 2 - 3 times a day, 1 - 2 drops in each eye in the lower conjunctival sac. Do not use continuously for more than 4 days without consulting an ophthalmologist. If there is no improvement within 2 days, then therapy should be discontinued.

    The dosage regimen should be strictly observed. Overdose and prolonged use should be avoided. With prolonged use there is a risk of developing toxic effects. The possibility of overdose, which is caused by systemic absorption of tetrizoline, is increased in young children (especially if accidentally swallowed). Tetrizoline eye drops should only be used for mild eye irritation. If hyperemia and irritation of the conjunctiva are associated with an infectious process, chemical injury to the cornea, or the presence of a foreign body, then consultation with an ophthalmologist is necessary. If within 2 days after starting to use eye drops, the symptoms of the disease become more pronounced, persist, or an adverse reaction develops, then it is necessary to discontinue the drug and consult an ophthalmologist. If you develop a headache, intense pain in the eyes, blurred vision, redness of the eyes, sudden appearance of floating spots in front of the eyes, double vision or pain when exposed to light, you should immediately consult a doctor. Contact lenses are removed before instillation of the drug and reinstalled 15 minutes after it. Due to the possible deterioration of the clarity of soft contact lenses, direct contact of eye drops with them should be avoided. During therapy, care should be taken when working with machinery and driving a car (after using eye drops, blurred vision and pupil dilation may occur).

    Contraindications for use

    Hypersensitivity; nasal drops: up to 2 years of age (for a 0.05% solution), up to 6 years (for a 0.1% solution), dry rhinitis; eye drops: age up to 2 years, severe eye pathology (dry eye syndrome, glaucoma, epithelial endothelial dystrophy of the cornea).

    Restrictions on use

    Severe pathology of the circulatory system (including arrhythmia, coronary heart disease, arterial hypertension, cardiac aneurysm), diabetes mellitus, hyperthyroidism, pheochromocytoma, period of therapy with drugs that increase blood pressure, including monoamine oxidase inhibitors.

    Use during pregnancy and breastfeeding

    Due to the risk of systemic adverse reactions, the use of tetrizoline during pregnancy and breastfeeding is possible only after careful comparison of the expected benefit to the mother and the possible risk to the child or fetus. It is not known whether tetrizoline is excreted in breast milk. There are no reproductive studies in animals.

    Side effects of tetrizoline

    Organ of vision: increased intraocular pressure, dilated pupils, reactive hyperemia, burning sensation;

    nervous system: headache, drowsiness, tremor, weakness, sleep disturbance, dizziness;

    digestive system: nausea;

    cardiovascular system: cardiac dysfunction, palpitations, arterial hypertension;

    endocrine system: hyperglycemia;

    respiratory system: when using drops in the nose - a tingling and burning sensation in the nose, dryness of the nasal cavity, sneezing; if the dose is exceeded or prolonged use - the development of secondary edema and hyperemia of the nasal mucosa;

    other: allergic reactions.

    Interaction of tetrizoline with other substances

    Tetrizoline is incompatible with monoamine oxidase inhibitors (risk of developing hypertension).

    Overdose

    In case of an overdose of tetrizoline, pupil dilation, cyanosis, nausea, fever, tachycardia/bradycardia, convulsions, arterial hypertension, shock-like syndrome with bradycardia and hypotension, and dizziness develop. In children, an overdose can manifest itself as depression of the central nervous system, which is accompanied by excessive sweating, drowsiness, severe hypotension, even shock. Necessary: ​​taking activated carbon, gastric lavage, symptomatic treatment (use of anticonvulsants, antipyretics, oxygen inhalation); There is no specific antidote.

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    Tetrizoline - instructions for use, composition, indications, analogues and reviews

    Pharmacological group of Tetrizoline eye drops - Alpha adrenergic agonists. Anticongestants. The names of the drugs are Berberyl N, Visin, Octilia.

    Composition and release form

    Tetrizoline release forms

    The drops are transparent and have no color. The liquid is supplied in cardboard packaging with 15 ml bottles.

    Half of the drug consists of tetrizoline hydrochloride. The remaining half consists of auxiliary substances, such as purified water, boric acid, sodium chloride, etc.

    Tetrizoline instructions for use of the drug

    How to use correctly: Tetrizoline dosage regimen

    Doses and frequency of use of Tetrizoline eye drops Adults and children over 6 years of age: 1 drop in each eye every 6 hours as needed.

    Eye drops onset of action Quick, within 5 minutes

    Duration of action of Tetrizoline eye drops : About 6 hours

    If you miss taking eye drops, use Tetrizoline eye drops as soon as you remember. If it is near the time of your next dose, skip the previous one and return to your regular schedule. Do not double the next dose

    Discontinuation of use Continuous use is possible for no more than 4 days.

    Tetrizoline eye drops special instructions Before putting Tetrizoline eye drops into your eyes, wash your hands. To avoid contamination, ensure that the tip of the pipette does not touch your eye, fingers, or other surfaces. If no effect is observed within 48 hours after starting to use eye drops, you should stop using the drug and consult a doctor.

    Medicinal properties of Tetrizoline

    The medicine reduces redness by narrowing the superficial blood vessels in the white layer of the eye (sclera).

    Indications, contraindications and side effects when using Tetrizoline

    Indications for use of Tetrizoline

    To reduce redness, irritation and itching of the eyes due to mild inflammation, fatigue or allergic conjunctivitis.

    Contraindications and restrictions when using Tetrizoline

    Restrictions on the use of the product include severe eye diseases (angle-closure glaucoma), children (up to 3 years), arterial hypertension, increased thyroid function, pregnancy and breastfeeding.

    Side effects from the use of Tetrizoline

    Dilated pupils, increased intraocular pressure, burning sensation. Rarely, increased blood pressure, headache, rapid or irregular heartbeat, excitability, anxiety, increased redness of the eyes, nausea

    Precautions when using Tetrizoline eye drops

    Over 60 years of age No special problems are expected when using the product.

    Driving and operating machinery Avoid these activities until you find out how Tetrizoline eye drops affect you.

    Alcohol when using Tetrizoline No special precautions required

    Overdose Dizziness, headache, rapid, arrhythmic or heavy heartbeat, trembling, insomnia. Call your doctor, emergency services, or the nearest poison control center immediately.

    Tetrizoline Interactions: Before starting this medication, talk to your doctor if you are using maprotiline or tricyclic antidepressants. Incompatible with monoamine oxidase inhibitors.

    Tetrizoline analogs

    Analogues of the drug based on the active substance can be called:

    • Visine
    • Visoptin
    • Tetrizoline analogue - Adrianol for adults
    • Noxivin
    • Nozacar
    • Analogue of the drug - Oxymetazoline
    • Otrivin.

    Price of the drug in pharmacies

    Check out the price of Tetrizoline eye drops in 2018 and cheap analogues >>> The cost of Tetrizoline eye drops in different pharmacies can vary significantly. This is due to the use of cheaper components in the drug and the pricing policy of the pharmacy chain. But the important thing is that the price difference between foreign and Russian analogues remains almost unchanged.

    On the MedMoon.ru website, medications are classified both alphabetically and by effect on the body. We publish only the most current and new medications. Instructions for use of Tetrizoline eye drops are regularly updated at the request of manufacturers.

    Other related articles:

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    Source: http://www.medmoon.ru/medicina/tetrizolin_glaznye_kapli.html

    Tetrizoline

    Content

    Structural formula

    Russian name

    The Latin name of the substance is Tetrizoline

    Chemical name

    4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole (as hydrochloride)

    Gross formula

    Pharmacological group of the substance Tetrizoline

    Nosological classification (ICD-10)

    CAS code

    Characteristics of the substance Tetrizoline

    Tetrizoline hydrochloride is easily soluble in water and alcohol, very slightly soluble in chloroform, practically insoluble in ether. The pH of a 1% aqueous solution is 5.0–6.5. Molecular weight 236.75.

    Pharmacology

    Stimulates alpha adrenergic receptors. When applied topically in the form of eye drops, it reduces swelling of the conjunctiva, burning sensation, irritation, itching, soreness of the mucous membrane of the eyes, and lacrimation.

    When used in the form of nasal drops, it causes a narrowing of the small arterioles of the nasal passages, reduces swelling of the nasal mucosa and reduces secretion.

    When applied topically, it is practically not absorbed. The effect develops within a few minutes and lasts 4–8 hours.

    Application of the substance Tetrizoline

    Swelling of the conjunctiva, secondary hyperemia in allergic eye diseases, irritation of the conjunctiva (as a result of exposure to chemical and physical factors, including smoke, dust, chlorinated water, bright light, cosmetics, contact lenses), catarrhal conjunctivitis.

    Swelling of the nasal mucosa in patients suffering from rhinitis, pharyngitis, sinusitis, hay fever, as well as to reduce swelling of the nasal mucosa if diagnostic and therapeutic measures are necessary.

    Contraindications

    Hypersensitivity; eye drops: severe eye diseases (glaucoma, dry eye syndrome, epithelial endothelial corneal dystrophy), children under 2 years of age; nasal drops: dry rhinitis, children up to 2 years of age (0.05% solution), up to 6 years of age (0.1% solution).

    Restrictions on use

    Severe cardiovascular diseases (including ischemic heart disease, arrhythmia, cardiac aneurysm, arterial hypertension), hyperthyroidism, diabetes mellitus, pheochromocytoma, period of treatment with drugs that increase blood pressure, incl. MAO inhibitors.

    Use during pregnancy and breastfeeding

    Due to the likelihood of systemic side effects, use during pregnancy and breastfeeding is possible only after careful comparison of the possible benefits to the mother and the risk to the fetus or child. No reproductive studies have been conducted in animals. It is not known whether tetrizoline is excreted into breast milk.

    Side effects of the substance Tetrizoline

    Eye drops: pupil dilation, increased intraocular pressure, burning sensation and reactive hyperemia of the eye.

    Nasal drops: burning and tingling in the nose, sneezing, dry nasal mucosa; with prolonged use or exceeding the dose - secondary edema, hyperemia of the nasal mucosa.

    Systemic effects: headache, dizziness, weakness, tremor, insomnia, increased blood pressure, palpitations, nausea, hyperglycemia, allergic reactions.

    Interaction

    Incompatible with MAO inhibitors (possible development of hypertension).

    Overdose

    Symptoms: pupil dilation, nausea, cyanosis, fever, convulsions, tachycardia/bradycardia, arterial hypertension, dizziness, shock-like syndrome with hypotension and bradycardia. Overdose in children can manifest as depression of the central nervous system, accompanied by drowsiness, excessive sweating, severe hypotension, even shock.

    Treatment: administration of activated carbon, gastric lavage, symptomatic therapy (oxygen inhalation, use of antipyretics, anticonvulsants). A specific antidote is unknown.

    Routes of administration

    Precautions for the substance Tetrizoline

    The dosage regimen must be strictly observed. Long-term use and overdose should be avoided. With prolonged use, toxic effects may develop. The risk of overdose due to systemic absorption of the drug is high in newborns and small children (especially if accidentally swallowed).

    Tetrizoline in the form of eye drops is advisable to use only for mild eye irritation. If irritation and hyperemia of the conjunctiva are associated with an infectious disease, the presence of a foreign body or chemical injury to the cornea, consultation with an ophthalmologist is necessary.

    If within 48 hours after starting the use of eye drops, the symptoms of the disease persist/become more pronounced or a side effect appears, you should stop using the drug and consult an ophthalmologist. If you experience intense eye pain, headache, blurred vision, sudden appearance of floaters in front of your eyes, red eyes, pain when exposed to light, or double vision, you should immediately consult a doctor.

    When wearing contact lenses, they are removed before instillation of the drug and reinstalled 15 minutes after it. Direct contact of eye drops with soft contact lenses should be avoided due to possible disruption of their transparency.

    During the treatment period, care must be taken when driving a car and operating machinery (after using eye drops, the pupil may dilate and blurred vision may occur).

    Interactions with other active ingredients

    Trade names

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    Source: http://www.rlsnet.ru/mnn_index_id_1659.htm

    Tetrizoline: description, instructions, price

    Tetrizoline price and availability in city pharmacies

    Republic, 171″ tipadr=”g. Tyumen, Republic, 171″ href=”/aptechnaya-set-zhivika”>Republic, 171

    Republic, 171″ tipadr=”g. Tyumen, Republic, 171″ href=”/aptechnaya-set-zhivika”>Republic, 171

    Republic, 171″ tipadr=”g. Tyumen, Republic, 171″ href=”/aptechnaya-set-zhivika”>Republic, 171

    Republic, 171″ tipadr=”g. Tyumen, Republic, 171″ href=”/aptechnaya-set-zhivika”>Republic, 171

    Valeria Gnarovskaya, 8″ tipadr=”g. Tyumen, Valeria Gnarovskaya, 8″ href=”/aptechnaya-set-zhivika-1″>Valeria Gnarovskaya, 8

    Valeria Gnarovskaya, 8″ tipadr=”g. Tyumen, Valeria Gnarovskaya, 8″ href=”/aptechnaya-set-zhivika-1″>Valeria Gnarovskaya, 8

    Valeria Gnarovskaya, 8″ tipadr=”g. Tyumen, Valeria Gnarovskaya, 8″ href=”/aptechnaya-set-zhivika-1″>Valeria Gnarovskaya, 8

    Valeria Gnarovskaya, 8″ tipadr=”g. Tyumen, Valeria Gnarovskaya, 8″ href=”/aptechnaya-set-zhivika-1″>Valeria Gnarovskaya, 8

    Stanislav Karnatsevich, 12″ tipadr=”g. Tyumen, Stanislav Karnatsevich, 12″ href=”/aptechnaya-set-zhivika-2″>Stanislav Karnatsevich, 12

    Stanislav Karnatsevich, 12″ tipadr=”g. Tyumen, Stanislav Karnatsevich, 12″ href=”/aptechnaya-set-zhivika-2″>Stanislav Karnatsevich, 12

    Stanislav Karnatsevich, 12″ tipadr=”g. Tyumen, Stanislav Karnatsevich, 12″ href=”/aptechnaya-set-zhivika-2″>Stanislav Karnatsevich, 12

    Stanislav Karnatsevich, 12″ tipadr=”g. Tyumen, Stanislav Karnatsevich, 12″ href=”/aptechnaya-set-zhivika-2″>Stanislav Karnatsevich, 12

    Lenina, 63/1″ tipadr=”g. Tyumen, Lenina, 63/1″ href=”/apteka-122-flora-ao-atd-panatseya”>Lenina, 63/1

    Source: http://lek-info.ru/tetrizolin

    VizOptic eye drops: instructions for use, tetrizoline hydrochloride 0.5 mg

    VizOptic eye drops are an alpha-adrenergic agonist. Vasoconstrictor and decongestant drug. Reduces swelling of conjunctivitis, burning sensation, pain in the mucous membrane of the eye, lacrimation. The effect after use occurs within a few minutes and lasts for 4-8 hours.

    Registration number: LCP/08 dated 09/04/2008

    Trade name of the drug: VizOptic

    International nonproprietary name: Tetrizoline

    Chemical name: 4,5-dihydro-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-imidazole monohydrochloride

    Dosage form: eye drops

    Photo of VizOptic eye drops showing the composition

    VizOptic eye drops composition

    Composition: 1 ml of the drug contains:

    Active ingredient: tetrizoline hydrochloride - 0.5 mg.

    Auxiliary components: boric acid, sodium tetraborate decahydrate, disodium edegate dihydrate, benzalkonium chloride, purified water.

    Transparent colorless solution.

    Pharmacotherapeutic group: alpha adrenergic agonist

    Alpha adrenergic stimulant, has a vasoconstrictor and anti-edematous effect. When applied topically, it reduces swelling of the conjunctiva, burning sensations, soreness of the mucous membrane of the eyes, and lacrimation. The vasoconstrictor effect develops within a few minutes and lasts 4-8 hours.

    When applied topically, systemic absorption is low.

    VizOptic indications for use

    • moderate eye irritation: itching, swelling and hyperemia of the conjunctiva, burning, lacrimation, scleral injection caused by chemical and physical factors (dust, cosmetics, swimming in chlorinated water, exposure to bright light or radiation from a computer monitor);
    • allergic conjunctivitis.

    VizOptic contraindications

    Hypersensitivity to the components of the drug, glaucoma, endothelial-epithelial dystrophy of the cornea, children (up to 3 years), acute cardiovascular failure, bacterial infection of the eye, foreign body of the eye.

    Arterial hypertension, arrhythmias, aneurysm, hyperthyroidism, pheochromocytoma, diabetes mellitus, severe organic diseases of the heart and blood vessels (including coronary heart disease (CHD), period of treatment with MAO inhibitors and other drugs that increase blood pressure (BP), diabetes mellitus.

    Use during pregnancy and breastfeeding is only possible if the intended benefit outweighs the risk to the mother or child.

    VizOptic eye drops: cheaper analogues

    VizOptic eye drops: dosage and method of application

    Locally. For adults and children over 3 years old, in each eye in the lower conjunctival sac - 1-2 drops 2-3 times a day.

    If improvement does not occur within 48 hours, further use should be stopped and consult a doctor.

    VizOptic: side effects

    Local: increased intraocular pressure, burning sensation and reactive hyperemia of the eye, rarely - pupil dilation.

    Systemic: increased blood pressure, hyperglycemia, cardiac dysfunction, headache, nausea, drowsiness, weakness, tremor, dizziness, insomnia, tachycardia, allergic reactions.

    The development of systemic symptoms of overdose is possible when the drug is accidentally or intentionally taken orally or when the dosage is exceeded when applied topically.

    Symptoms: pupil dilation, nausea, cyanosis, fever, convulsions, arrhythmias, arterial hypertension, pulmonary edema, dyspnea. Excessive systemic absorption of imidazole derivatives can lead to CNS depression, with drowsiness, hypothermia, bradycardia, collapse, apnea and coma.

    The risk of overdose symptoms associated with drug absorption is high in young children, especially if swallowed. Overdose in children can manifest as depression of the central nervous system, accompanied by drowsiness, excessive sweating, severe hypotension, even shock.

    Treatment: specific antidote is unknown. Activated charcoal, gastric lavage, oxygen inhalation, and the use of antipyretics and anticonvulsants are prescribed. To reduce DD, use phentolamine 5 mg in a 0.9% NaCl solution slowly intravenously or 100 mg orally.

    Interaction with other drugs

    The drug should not be used simultaneously with MAO inhibitors (phenelzine, nialamide, iproniazid, etc.) and within 10 days after stopping their use.

    Concomitant use with monoamine oxide inhibitors, tricyclic antidepressants, and guanethidine can cause hypertension and tachycardia.

    Concomitant use with resepia, insulin, propranolol, general anesthetics, and atropine increases the risk of cardiovascular effects of tetranzoline.

    Simultaneous use with guanethidine can provoke mydriasis (dilation of the pupil), with temporary visual impairment.

    Tetrizoline in the form of eye drops is advisable to use only for mild eye irritation. If irritation and hyperemia of the conjunctiva are associated with an infectious disease, the presence of a foreign body or chemical injury to the cornea, consultation with an ophthalmologist is necessary.

    If within 48 hours after starting the use of eye drops, the symptoms of the disease persist, become more pronounced, or side effects appear, you should stop using the drug and consult an ophthalmologist.

    If you experience intense pain in the eyes, headache, blurred vision, sudden appearance of “floating spots” in front of the eyes, redness of the eyes, pain when exposed to light, or double vision, you should immediately consult a doctor.

    When wearing contact lenses, they are removed before instillation of the drug and reinstalled 15 minutes after it. Direct contact of eye drops with soft contact lenses should be avoided due to possible disruption of their transparency.

    Impact on the ability to drive vehicles and work with special equipment

    During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration, speed of psychomotor reactions and good vision (after using eye drops, pupil dilation and blurred vision are possible).

    Eye drops 0.05%. 15 ml of solution in a white polymer dropper bottle closed with a polymer cap with a safety ring. One dropper bottle along with instructions for use in a cardboard box.

    Photo of a bottle of VizOptic eye drops 15 ml

    Store at a temperature of 15-25°C in original packaging.

    Keep out of the reach of children.

    Photo of VizOptic eye drops showing storage conditions

    5 years. After opening the bottle, the drops should be used within 4 weeks.

    Do not use after expiration date.

    Photo of VizOptic eye drops showing the series, date of manufacture and expiration date of the drops

    Conditions for dispensing from pharmacies

    Without a doctor's prescription.

    Photo of VizOptic eye drops showing the price

    K.O. Rompharm Company CPJI.

    St. Eroilor 1 A, Otopeni, Romania.

    Complaints regarding the quality of the drug should be sent to:

    Representative of the manufacturer in the Russian Federation Rompharma LLC

    117639, Moscow, Varshavskoe highway, no. 95, bldg. 1, office 446, tel./fax:

    VizOptic eye drops summary (instructions for use) in photographs

    Photo of instructions for use of VizOptic eye drops, part 1

    Photo of instructions for use of VizOptic eye drops, part 2

    VizOptic eye drops: reviews of the drug

    For conjunctivitis, VizOptic drops were prescribed. I liked it very much. The effect after use really came quickly, the pain went away. The discharge began to stop in the evening. By the next morning there was nothing left of the conjunctivitis. I would like to note that I had allergic conjunctivitis, which, as it turned out, was an allergy to the new mascara.

    I often suffer from dry eyes. As a result, itching, burning, and discomfort when blinking appear. I tried many drops, some worked, but turned out to be unreasonably expensive. These relieve symptoms well, and the price is quite decent. It happens to me that my eyes seem to swell, but after instillation my eyes look great. In general, I myself am an allergy sufferer. All my symptoms are caused either by incorrectly selected cosmetics or by dust. Good drops, they do their job perfectly. It's good that you can buy it without a prescription.

    Dry eye syndrome is familiar to many computer owners; of course, it can occur due to many factors. But it is the computer that is the trouble for our eyes. I’m no exception; by evening my eyes seem to crumble into small pieces. The burning and itching does not go away. After consulting with an ophthalmologist, I purchased VizOptic drops. Unfortunately, they didn't help me at all. The discomfort did not go away after use. There are also side effects. And the price is not the lowest. I won't advise.

    After buying a new mascara, an allergy appeared, I thought it would itch and go away on its own. But it was not there. I had to go to the doctor with red eyes, he prescribed VizOptic. After using it, the symptoms went away, but after a few days everything came back again. I don’t know whether I have unsolvable problems, or whether the remedy is simply weak. After changing to another drug, everything returned to normal.

    Good drops help me cope with the redness of my eyes that occurs after a hard day or working at the computer. There are cheaper drops, but there are also expensive analogues. Therefore, the price, I think, is average. Unfortunately, they do not have any therapeutic effect, they only relieve symptoms. I had no allergic reactions or side effects.

    I’ve been familiar with the drops for a long time, they perfectly tidy up my eyes. They act quickly and relieve symptoms well. The thing is that I like to sit at the computer late into the night, and in the morning my eyes become red from lack of sleep. So you have to mask it with drops. It is enough to drop it once and the redness will decrease. The price is affordable, the result is good, no allergic reactions were noticed.

    For the last few years I have been wearing glasses due to vision problems. I thought that the redness and fatigue due to the fact that the glasses were not anti-glare and the sun were the result of my problems. Then I realized that this was not connected at all. Because I purchased other glasses with anti-glare effect. I can’t say that I spend a lot of time at the computer or TV. VizOptic drops are a good analogue to the expensive Visin, but they work the same way. Redness and fatigue go away very quickly. After just one application the result is visible. You can buy it without a doctor’s prescription; there have never been any reactions to the drug. The price is affordable.

    3 comments to the article

    Due to the nature of my work, I spend a lot of time in front of a computer monitor. Therefore, the eyes, of course, get tired. A year ago I asked the pharmacy for an inexpensive analogue of Visina. I was offered Visoptik. These eye drops cost 2, or even 3 times less. I can't say that these eye drops work better than the expensive ones. But not worse, that's for sure. Therefore, I don’t see any point in overpaying.

    You know, I also think that there is no point in paying much more for the same effect. Although someone may have a different opinion on this matter. When my husband started working as a welder, VizOptic drops helped us a lot. After the first day of work, his eyes were very inflamed. And friends advised me to use these drops. I was simply amazed at such a quick result. In the morning everything was gone. Well, very good drops.

    It’s simply impossible to disagree; it’s actually a wonderful drug. The fact is that I have an eternal problem: constantly red eyes. I react to both the wind and the bright rays of the sun; my eyes quickly get tired even when watching TV. I used to use Vizin, but recently it has become very expensive, so I decided to try VizOptic and, you know, I was not disappointed. The quality of the drops is excellent. the redness goes away very quickly. and lasts them for a long time. In general, I am one hundred percent satisfied with the quality and price.

    Source: http://pro-tabletki.ru/lekarstvennye-preparaty-dlya-glaz/kapli-glaznye-vizoptik-instrukciya-po-primeneniyu-tetrizolina-gidroxlorid-05-mg.html

    Eye drops "Visoptic" based on tetrizoline hydrochloride

    The drug "Visoptic" is a medicinal colorless solution, transparent drops for the eyes, based on tetrizoline hydrochloride. The active component is contained in the drug: 1 ml - 500 mcg (0.05%). Other additional compounds in the drug:

    • sodium tetraborate;
    • disodium edetate dihydrate;
    • benzalkonium chloride;
    • boric acid;
    • distilled water.

    The medicine is packaged - a plastic bottle in the form of a small dropper, 15 ml, in a small cardboard box indicating the date of manufacture.

    The optimal temperature for storing the medicine should be no higher than 25 °C, in places protected from children. In a single package, the shelf life of eye drops can be 60 months. If the Visoptika bottle is opened, the eye product should be used for no more than one month. The remains of the drug are disposed of.

    Application of eye drops "Vizoptik"

    The ophthalmic drug represents the pharmacological group of alpha-adrenergic agonists. Has an anti-edematous effect, constricts blood vessels. The drug "Visoptic" is used topically, it:

    • reduces swelling;
    • relieves burning sensation;
    • eliminates pain in the eye mucosa;
    • stops lacrimation.

    Elimination of symptoms after instillation can be felt in approximately 3-4 minutes, relief lasts 4-7 hours.

    At the first signs of redness and irritation of the eyes, the drug “Visoptic” is recommended. But in cases of infection, foreign body entry, injury from chemicals, cosmetics, this medicine should not be used without consulting a doctor.

    City residents often suffer from dry eye syndrome for the following reasons:

    • spend many hours at the computer;
    • exposed to air conditioning or fans;
    • wear contact lenses;
    • smoke often.

    Visoptik drops help relieve the syndrome in the initial stages; in more complex cases, it is necessary to begin treatment with drugs prescribed by specialists. They are also used in the complex treatment of allergic conjunctivitis.

    Contraindications to the use of the drug

    Visoptic drops should not be used if the patient has the following diseases:

    • glaucoma;
    • acute heart failure;
    • allergic reactions to the components of the drug;
    • high blood pressure;
    • thyroid diseases;
    • arrhythmia;
    • diabetes.

    Under the supervision of a physician, eye drops are used with great caution during treatment with MAO inhibitors and other drugs containing tetrizoline.

    Adverse reactions

    When using the drug "Visoptik" some adverse reactions may occur:

    • increased intraocular pressure;
    • redness of the eyes;
    • burning;
    • pupil dilation;
    • hyperglycemia;
    • dizziness;
    • insomnia.

    The daily dose of eye drops is: no more than 3 times daily, instill up to 2 drops into the conjunctival sac of the eyes. Do not use eye drops that are below room temperature.

    Accidental overdose

    An overdose occurs if the medicine is accidentally ingested. In cases where a child has taken the medicine, the following occurs: drowsiness, sweating, severe hypotension, and sometimes shock may occur. In adults, an overdose can cause: arrhythmia, nausea, dilated pupils, fever, pulmonary edema.

    At the initial signs of an overdose, first aid is provided - they take activated carbon, oxygen inhalations, and wash out the stomach. At elevated temperatures, take medications that reduce fever, as well as against high blood pressure.

    During pregnancy and breastfeeding, a doctor prescribes Visoptik drops only in cases of extreme necessity. Users of these eye drops claim that the medicine relieves all unpleasant symptoms within a short time; many call them lifesavers for tired eyes.

    Equivalent analogues

    When a person has to work at a computer for a long time, dry eyes appear, a syndrome that is accompanied by unpleasant sensations and itching. These symptoms can be removed by using decoctions of chamomile and thyme and drops containing tetrizoline analogues.

    Equivalent analogues of Visoptik eye drops are:

    They are as effective in treatment as Vizoptik, the only difference is the price of the drugs in pharmacies.

    Use of Tetrizoline eye drops

    For painful eye symptoms, you can use Tetrizoline eye drops, which are indicated for swelling and irritation of the conjunctiva, allergies, and catarrhal conjunctivitis. Irritations can be characterized by chemical and physical derivatives - smoke, dust, water with bleach, low-quality cosmetics, contact lenses.

    If after 4 days of continuous use of Tetrizoline (2-3 times daily, 1-2 drops), no relief is observed, the drug should be discontinued and consult a specialist.

    If symptoms worsen on the 3rd day after starting to use the drops, further treatment with the drug is not recommended. Tetrizoline should not be used with monoamine oxidase inhibitors.

    Source: http://glaz.guru/lechenie/glaznye-kapli-vizoptik-na-osnove-gidrohlorida-tetrizolina.html

    Tetrizoline

    Russian name

    Latin name

    Chemical name

    4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole (as hydrochloride)

    Gross formula

    Pharmacological group

    Nosological classification (ICD-10)

    H57.1 Eye pain

    J00 Acute nasopharyngitis [runny nose]

    J01 Acute sinusitis

    J02 Acute pharyngitis

    J30 Vasomotor and allergic rhinitis

    J999* Diagnosis of respiratory diseases

    R60.0 Localized edema

    S05 Injury to the eye and orbit

    T78.4 Allergy, unspecified

    CAS code

    Characteristic

    Tetrizoline hydrochloride is easily soluble in water and alcohol, very slightly soluble in chloroform, and practically soluble in ether. The pH of a 1% aqueous solution is 5.0–6.5. Molecular weight 236.75.

    Pharmacology

    Stimulates alpha adrenergic receptors. When applied topically in the form of eye drops, it reduces swelling of the conjunctiva, burning sensation, irritation, itching, soreness of the mucous membrane of the eyes, and lacrimation.

    When used in the form of nasal drops, it causes a narrowing of the small arterioles of the nasal passages, reduces swelling of the nasal mucosa and reduces secretion.

    When applied topically, it is practically not absorbed. The effect develops within a few minutes and lasts 4–8 hours.

    Application

    Swelling of the conjunctiva, secondary hyperemia in allergic eye diseases, irritation of the conjunctiva (as a result of exposure to chemical and physical factors, including smoke, dust, chlorinated water, bright light, cosmetics, contact lenses), catarrhal conjunctivitis.

    Swelling of the nasal mucosa in patients suffering from rhinitis, pharyngitis, sinusitis, hay fever, as well as to reduce swelling of the nasal mucosa if diagnostic and therapeutic measures are necessary.

    Contraindications

    Hypersensitivity; eye drops: severe eye diseases (glaucoma, dry eye syndrome, epithelial endothelial corneal dystrophy), children under 2 years of age; nasal drops: dry rhinitis, children up to 2 years of age (0.05% solution), up to 6 years of age (0.1% solution).

    Restrictions on use

    Severe cardiovascular diseases (including ischemic heart disease, arrhythmia, cardiac aneurysm, arterial hypertension), hyperthyroidism, diabetes mellitus, pheochromocytoma, period of treatment with drugs that increase blood pressure, incl. MAO inhibitors.

    Use during pregnancy and breastfeeding

    Due to the likelihood of systemic side effects, use during pregnancy and breastfeeding is possible only after careful comparison of the possible benefits to the mother and the risk to the fetus or child. No reproductive studies have been conducted in animals. It is not known whether tetrizoline is excreted into breast milk.

    Side effects

    Eye drops: pupil dilation, increased intraocular pressure, burning sensation and reactive hyperemia of the eye.

    Nasal drops: burning and tingling in the nose, sneezing, dry nasal mucosa; with prolonged use or exceeding the dose - secondary edema, hyperemia of the nasal mucosa.

    Systemic effects: headache, dizziness, weakness, tremor, insomnia, increased blood pressure, palpitations, nausea, hyperglycemia, allergic reactions.

    Interaction

    Incompatible with MAO inhibitors (possible development of hypertension).

    Overdose

    Symptoms: pupil dilation, nausea, cyanosis, fever, convulsions, tachycardia/bradycardia, arterial hypertension, dizziness, shock-like syndrome with hypotension and bradycardia. Overdose in children can manifest as depression of the central nervous system, accompanied by drowsiness, excessive sweating, severe hypotension, even shock.

    Treatment: administration of activated carbon, gastric lavage, symptomatic therapy (oxygen inhalation, use of antipyretics, anticonvulsants). A specific antidote is unknown.

    Directions for use and doses

    Conjunctivally, in each eye in the lower conjunctival sac - 1-2 drops 2-3 times a day. Without consulting an ophthalmologist, it should not be used continuously for more than 4 days. If improvement does not occur within 48 hours, treatment should be stopped.

    Intranasally, adults and children over 6 years old - 2-4 drops of 0.1% solution, children 2-6 years old - 2-3 drops of 0.05% solution in each nasal passage with an interval of at least 3 hours. Do not use more than 3–5 days (except for doctor's recommendations). Re-appointment is possible only after a few days.

    Precautionary measures

    The dosage regimen must be strictly observed. Long-term use and overdose should be avoided. With prolonged use, toxic effects may develop. The risk of overdose due to systemic absorption of the drug is high in newborns and small children (especially if accidentally swallowed).

    Tetrizoline in the form of eye drops is advisable to use only for mild eye irritation. If irritation and hyperemia of the conjunctiva are associated with an infectious disease, the presence of a foreign body or chemical injury to the cornea, consultation with an ophthalmologist is necessary.

    If within 48 hours after starting the use of eye drops, the symptoms of the disease persist/become more pronounced or a side effect appears, you should stop using the drug and consult an ophthalmologist. If you experience intense eye pain, headache, blurred vision, sudden appearance of floaters in front of your eyes, red eyes, pain when exposed to light, or double vision, you should immediately consult a doctor.

    When wearing contact lenses, they are removed before instillation of the drug and reinstalled 15 minutes after it. Direct contact of eye drops with soft contact lenses should be avoided due to possible disruption of their transparency.

    During the treatment period, care must be taken when driving a car and operating machinery (after using eye drops, the pupil may dilate and blurred vision may occur).

    Year of last adjustment

    Interactions with other active ingredients

    Tetrizoline is incompatible with halothane (ventricular fibrillation is possible).

    Tetrizoline is incompatible with maprotiline (a hypertensive crisis may develop).

    Source: http://www.med-09.ru/dv2103.htm

    Tetrizoline: instructions for use

    Almost every mother encounters a runny nose in children regularly. Having an effective remedy for this uncomfortable symptom on hand is every woman’s dream. Let's consider the features of the use of Tetrizoline hydrochloride, which is considered one of the most commonly prescribed drugs for rhinitis and more.

    Pharmacological properties

    Tetrizoline hydrochloride has two main pharmacological actions:

    • Vasoconstrictor.
    • Anticongestive (relieves swelling of the mucous membrane).

    Leads to stimulation of alpha adrenergic receptors. If used topically in the form of eye drops, it helps reduce swelling of the conjunctiva and reduce burning and itching sensations. It also relieves soreness in the eye mucosa and stops lacrimation.

    When using the drug in the form of drops for the nasal cavity, there is a spasm of small blood vessels, a decrease in swelling of the nasal mucosa and a decrease in mucus secretion. If Tetrizoline hydrochloride is administered topically, there is virtually no systemic absorption.

    It only takes a few minutes for the therapeutic effect to develop. The duration of pharmacological action lasts for 4-8 hours.

    Indications

    Today, Tetrizoline hydrochloride is successfully used in ophthalmological and otolaryngological practice. For what pathological conditions can this drug be recommended:

    • Runny nose.
    • Swelling of the nasal mucosa in children and adults, which can be observed with rhinitis, pharyngitis, sinusitis, etc.
    • If it is necessary to reduce swelling of the nasal mucosa to carry out diagnostic and therapeutic procedures.
    • Swelling and redness of the conjunctiva.
    • If you feel unpleasant discomfort, burning and itching in the area of ​​the conjunctiva of the eyes.
    • To quickly and effectively stop lacrimation.

    Contraindications

    Depending on the type of medication (eye or nasal drops), there will be corresponding contraindications, which are described in detail in the instructions for use. When not to use Tetrizoline hydrochloride, available in eye drops:

    1. The presence of hypersensitivity to the active substance of the drug.
    2. Glaucoma, when there is an increase in intraocular pressure.
    3. Dry keratoconjunctivitis. This disease is also called “dry eye” syndrome.
    4. Significant thinning of the cornea, which is characteristic of epithelial-endothelial dystrophy of the outer transparent membrane of the eye.
    5. Children under three years of age.
    6. Simultaneously use with drugs from the MAO inhibitor group (antidepressants).

    Contraindications for nasal drops:

    • The presence of hypersensitivity to the active substance of the drug.
    • Atrophic inflammation of the nasal mucosa (dry rhinitis).
    • 0.05% drops are contraindicated in children under two years of age.
    • 0.1% drops cannot be used to treat children under 6 years of age.
    • Simultaneous use with drugs from the MAO inhibitor group (antidepressants).

    For what diseases and pathological conditions should the drug Tetrizoline hydrochloride be prescribed with extreme caution:

    • Severe pathologies of the cardiovascular system (coronary disease, arterial hypertension, arrhythmia, aneurysm, etc.).
    • Hyperthyroidism.
    • Diabetes mellitus.
    • Pheochromocytoma.

    Tetrizoline hydrochloride is not used as an injection.

    Side effects

    When using the drug Tetrizoline hydrochloride, various adverse reactions may develop. What undesirable effects can be expected from the use of eye drops:

    • The pupil dilates.
    • Intraocular pressure increases.
    • There is a burning sensation and redness of the eye.

    What side effects can be observed from the administration of nasal drops:

    • Burning and tingling sensation in the nasal cavity.
    • Frequent attacks of sneezing.
    • The appearance of dry mucous membrane of the nasal passages.
    • In case of prolonged use or increasing dosage, secondary edema and redness of the nasal mucosa are noted.

    Systemic adverse reactions:

    • Headaches of varying intensity.
    • Dizziness.
    • Fatigue and fatigue.
    • The appearance of tremor.
    • Sleep disturbance.
    • High blood pressure.
    • Feeling of heartbeat.
    • Nausea.
    • Development of allergic reactions.

    Pregnancy and breastfeeding

    According to the official instructions for use, Tetrizoline hydrochloride can be prescribed by the attending physician if the potential benefits significantly outweigh the possible risks for the woman and fetus. There are no clinically confirmed data on the penetration of the active substance into breast milk. Targeted studies on the safety of using the drug during pregnancy and breastfeeding have not been conducted.

    Overdose

    In case of an overdose of Tetrizoline hydrochloride, the following clinical symptoms may develop:

    • The pupil dilates.
    • Temperature rise.
    • Nausea.
    • Convulsive attacks.
    • Blood pressure increases.
    • Fast/slow heartbeat.
    • State of shock.
    • Drowsiness.
    • Suppression of the functions of the central nervous system (lethargy, dizziness, impaired attention, etc.).

    What treatment measures should be taken to get rid of the symptoms of a drug overdose? First of all, it is necessary to carry out an effective gastric lavage and take activated carbon or similar drugs with adsorbing properties. If the situation requires it, symptomatic therapy is used. It should be noted that there is no specific antidote (antidote).

    The use of Tetrizoline hydrochloride in the form of drops for the eyes or nasal cavity should be agreed with the attending physician.

    special instructions

    It is recommended to strictly adhere to the dosage regimen and frequency of use of the drug. Prolonged use may result in adverse reactions. Under no circumstances should you use MAO inhibitors (antidepressants) together with medications from the group.

    The possibility of purchasing a medicinal product without a prescription does not provide any reason to neglect the consultation of a doctor or pharmaceutical specialist.

    Price and analogues

    Tetrizoline hydrochloride is produced by both domestic and foreign pharmaceutical companies. For example, this drug under the commercial name Tizin costs about 170 rubles for a 10 ml bottle of 0.05% solution. The following similar drugs with the active substance tetrizoline hydrochloride are currently available:

    When choosing an effective medicine, be sure to take into account the opinion and recommendations of a specialist. In most cases, the cost of foreign analogues is an order of magnitude more expensive than domestic drugs. Please note that some analogues of Tetrizoline hydrochloride are available exclusively in the form of eye drops.

    Source: http://elaxsir.ru/lekarstva/drugie-lekarstva/gidroxlorid-tetrizolina.html