Suprax for child

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Antibiotic Suprax for a child - take it correctly!

Suprax is a potent medicine that is most often taken when weaker antibiotics have not worked or a powerful antibacterial effect on the body is immediately needed.

Table of contents:

It quickly stops inflammation, removes complications and secondary infections.

Suprax needs to be taken only once a day.

This is convenient for small children.

Composition and indications for use

The antibiotic contains the main active ingredient cefixime, a thickener and flavoring additives, thanks to which the antibiotic has a pleasant caramel or strawberry taste. The most convenient form of Suprax for children is a suspension. It is sold in dry form: a 60 ml bottle with granules for dilution with water. The kit includes a dosing spoon.

In what cases does a pediatrician prescribe Suprax:

  • pharyngitis;
  • tonsillitis;
  • sinusitis;
  • bronchitis of all types, sore throat;
  • otitis media;
  • urinary tract infections without complications.

Do not give the drug for common childhood “cold” pathologies, so that microorganisms do not become resistant to the drug.

Under no circumstances should you prescribe Suprax to a child on your own. Usually, the disease is first treated with more gentle antibiotics, for example, Flemoxin or Cefazolin. And if they don’t work, then the doctor prescribes Suprax.

The unsystematic use of antibiotics can develop resistance to them in pathogenic bacteria. In the future, medications will either work too little or have no effect at all.

Suprax is not suitable for everyone. The instructions for use (download in pdf) describe a number of contraindications:

  1. Renal dysfunction.
  2. Age up to 12 years (only suspension is allowed, capsules are not allowed).
  3. Severe sensitivity to cephalosporin and penicillin antibiotics.
  4. Babies up to 6 months (only in case of emergency).

If a child has chronic renal failure or has ever suffered from pseudomembranous colitis, then Suprax should be taken with caution.

How to take the medicine

  • from 6 months to 1 year: 2.5 - 4 ml;
  • from 2 to 4 years: 5 ml;
  • from 5 to 11 years: 6-10 ml.

It’s easy to prepare a suspension at home: add water to a bottle of granules and mix thoroughly.

For a child over 11 years old and weighing more than 50 kg, the dosage is the same - 400 mg of the active substance per day.

If you weigh less than 50 kg, the dosage is calculated using the formula 8 mg of active substance per 1 kg of body weight.

Children with a strong constitution and weighing more than 50 kg should not take more than 400 mg of medication per day. It turns out that Maxim, weighing 50 kg, and Dima, weighing 56 kg, need to prepare the same amount of antibiotic.

The usual course of treatment is 10 days. If the child recovers quickly, then you can stop taking the medicine after a week, but not earlier. Usually, signs of recovery are visible already on the 2-3rd day, despite the fact that the causative agents of the disease have not yet been completely destroyed. By stopping the medicine too early, you will give the bacteria a kind of “vaccination”, and next time Suprax will not help.

Prepare the suspension correctly:

  1. Boil the water in advance and cool it to room temperature.
  2. To prepare the suspension, the bottle with granules must be turned over and shaken vigorously.
  3. Then add 40 ml (1 approach - 20 ml) of water in 2 approaches; After each time, shake the bottle until a homogeneous mixture is obtained.
  4. The finished medicine is left to stand for 5 minutes. During this time, the granules will completely disintegrate.
  5. Shake the Suprax suspension before each use. The antibiotic can also be diluted in breast milk, juice or compote. If the child is already eating on his own, then the diluted medicine can be mixed into porridge or soup, but not forgetting the dosage.

The medicine can be added to porridge or puree.

Like all strong drugs, Suprax has an aggressive effect on the intestinal microflora. To support the child’s body, it is advisable to take probiotics, for example, Linex or Bifidumbacterin, along with the antibiotic.

Side effects

Often the possibility of side effects from antibiotics stops parents: they fear that the drug will do more harm than good. The consequences of an untreated disease are many times more serious than the probable (but not obligatory!) complications after taking Suprax, so if your doctor has prescribed it, follow the instructions.

Possible side effects:

Suprax's analogs

The original antibiotic is produced by the Indian company Hikma Pharmaceuticals. The packaging is sold in rubles.

An analogue of Suprax - Pancef - the drug is absorbed very quickly, which means the effect of the treatment will not be long in coming.

The most popular analogue of the Suprax suspension, according to reviews, is Pancef. They have the same active ingredient - Cefixime, but the price is slightly different. The drug is produced by the Alkaloid company from Macedonia and costs rubles.

In addition to Pancef, antibacterial drugs Ixim Lupine (India, approximately 400 rubles), Cemidexor (China, can be bought for 300 rubles) and Cefix (Jordan, no more than 300 rubles) can be considered analogues. All of these medicines contain the active ingredient Cefixime, but they are sold in tablet form.

What they write on the forums

Young mothers are distrustful, so they carefully research medications and look at real reviews on the Internet. This collection of reviews from parents who treated their child with Suprax will help you make a decision.

“This medicine was prescribed to us by our pediatrician. It helped! The child was completely okay, he lay all the time, and after a couple of days he was already jumping around the apartment. The only negative is the rash; my son itched for several days.”

“Suprax helped us with obstructive bronchitis. There were no side effects. We took Bifidumbacterin together to preserve the microflora.”

“An antibiotic is like an antibiotic. There were no great or terrible consequences. We calmly took the course as prescribed by the doctor, my daughter is healthy.”

Let's sum it up

  • Suprax is a strong antibiotic.
  • It is convenient for children to give the medicine in the form of a suspension.
  • After a course of any antibiotic, you need to restore the intestinal microflora.
  • The dosage must be carefully calculated. You cannot give medicine by eye!
  • It is advisable to take probiotics in parallel with taking Suprax and after completion of treatment.

Author: Katerina Koroleva

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Source: http://www.o-my-baby.ru/zdorovie/lekarstva/antibiotiki/suspenziya-suprax.htm

Suprax for children

Suprax is a third generation antibiotic with the active ingredient cefixin. The drug is active against various gram-negative and gram-positive microorganisms and has a wide spectrum of action.

So the indications for the use of Suprax for children are infections of the respiratory tract, urinary system, ENT organs, soft tissues, bones, etc. It is successfully used for tonsillitis (inflammatory processes of the tonsils), pharyngitis, sinusitis, otitis and inflammation of the middle ear.

It is not recommended to start treatment immediately with the use of Suprax, due to the possible addiction of the body to this potent medicine. After which, it stops responding to other, less effective, but safer ones. This antibiotic has found especially wide use in inpatient treatment of patients.

Directions for use and dosage

Suprax is present on the pharmacological market in the form of capsules, granules and suspensions. The latest release form is perfect for children. After all, everyone probably remembers that it’s quite easy to give liquid to a child; in addition, the suspension has a pleasant caramel taste that kids like.

The suspension is available in dry form, but is easy to prepare: to do this, you need to add 40 ml of chilled boiled water to the bottle with granules in two stages. Shake after each addition of water until a uniform substance is formed. The suspension must be allowed to settle, and the finished solution should be shaken again before use.

If there are no other individual recommendations, the instructions for use of Suprax determine the daily dose for children 5-11 years old in 6-10 ml of suspension, for children 2-4 years old - 5 ml, and for infants from 6 months to a year - 2.5-4 ml.

Required information

Of course, Suprax is a very powerful and reliable antibiotic, but this medicine is not suitable for everyone. There is a long list of side effects of Suprax, which frightens parents.

  • Dry mouth, diarrhea, flatulence, nausea, vomiting, anorexia, abdominal pain, liver transaminase activity, hyperbilirubinemia, gastrointestinal candidiasis, cholestasis, jaundice, dysbacteriosis; sometimes - pseudomembranous enterocolitis, stomatitis, glossitis;
  • Leukopenia, thrombocytopenia, neutropenia, pancytopenia, hemolytic anemia, aplastic anemia, agranulocytosis, bleeding;
  • Headache, dizziness, tinnitus;
  • Vaginitis;
  • Interstitial nephritis, renal dysfunction;
  • Allergic reactions and anaphylactic shock.

There are also strict contraindications for Suprax for children, although there are not many of them.

To avoid the occurrence of candidiasis and intestinal dysbiosis, simultaneously with this drug, doctors recommend products that normalize vaginal and intestinal microflora, antifungal drugs: Linex, Acipol, etc.

Up to six months of age, the appointment of Suprax is possible only if there are compelling indications and careful weighing of possible risks.

Parents should always remember that taking any antibiotics is possible only if a specific infection is diagnosed accurately enough. And only as prescribed by the attending physician.

Never make your own decision about using Suprax. Moreover, it is strictly forbidden to give antibiotics to children for prophylactic purposes or for “reinsurance.”

Source: http://doctor-detkin.ru/lekarstva/supraks/

Suprax suspension: instructions for use for children and adults

• Uncomplicated lesions of the ear, mastoid process: otitis media, mastoiditis.

• Not severe acute, chronic bronchitis.

• Uncomplicated gonorrhea.

• Not severe infections of the urinary tract, kidneys: pyelonephritis, cystitis, urethritis.

• Allergic reactions: rash, urticaria, anaphylactic shock, Quincke's edema, skin itching, transient increase in body temperature, eosinophilia (increase in eosinophils in the blood).

• Hematopoietic organs: decreased levels of leukocytes, neutrophils, platelets, hemolytic anemia.

• Urinary system: interstitial nephritis.

• Nervous system: dizziness, headaches.

Source: http://www.rasteniya-lecarstvennie.ru/3113-supraks-suspenziya-instrukciya-po-primeneniyu-dlya-detey-i-vzroslyh.html

"Suprax": instructions for use of suspension and tablets for children with dosage calculation, antibiotic analogues

In case of inflammatory processes of infectious origin, the doctor sometimes prescribes the child to take antibacterial drugs (as part of the therapeutic course). Parents are wary of strong medications. For tonsillitis, bronchitis, chronic pharyngitis, otitis media, sinusitis and other diseases, children are often prescribed the drug Suprax. What does it consist of? How does it work? How to take medication correctly? Are there any contraindications? What antibiotics can replace the drug? We will talk about this in this article.

Composition and release form of the drug

The product is available in tablet form (Suprax Solutab), as well as in the form of granules for preparing a suspension. The drug is produced by both domestic pharmaceutical companies and some foreign (Italian) ones. The active ingredient of the drug is a substance called cefixime. Each tablet contains 400 mg, and 5 ml of suspension contains 100 mg. Suprax contains a complex of auxiliary components, including:

  1. Strawberry flavoring;
  2. dye (“Sunset, yellow”);
  3. cellulose;
  4. calcium saccharin trisesquihydrate;
  5. silicon dioxide (colloidal);
  6. hyprolose;
  7. povidone.

Tablet form of Suprax

Action of the antibiotic

Suprax is an antibacterial agent of the third generation cephalosporin group; the main active ingredient is semi-synthetic. Effective in the treatment of pathological processes provoked by gram (+) and gram (-) bacteria. It is excreted from the patient’s body through the urinary system almost unchanged.

Indications for use

The use of Suprax is indicated for the treatment of pathological processes that were caused by bacteria sensitive to the action of the main active substance included in the drug. Suprax is prescribed for uncomplicated forms of gonorrhea (for example, if the disease develops in the urethra or cervix), shigellosis, infectious diseases of the respiratory tract, and otitis media. Also, the medicine is often used in the treatment of diseases of the urinary system that are of bacterial origin.

Instructions for using antibiotics with dosage calculation

The dose should be calculated by the doctor, taking into account the patient’s age and weight, the diagnosed pathology and the characteristics of the course of the disease.

How to prepare the suspension?

Preparation of a suspension for oral administration is a simple process; it should be performed in accordance with the instructions that come with each package of the drug. How to dilute Suprax suspension for children? To make the solution, you will need chilled boiled water, so it is better to boil the liquid in advance:

  1. The container with antibiotic granules must be shaken vigorously, turning over several times. Instead of special granules, you can take the medicine in tablet form, crush one piece (or half) into powder and dilute with water.
  2. Pour 20 ml of prepared water into a jar of granules. Shake the bottle several times until the mixture becomes homogeneous.
  3. Then add another 20 ml of liquid and shake vigorously again. The finished solution is left to stand for 5–7 minutes so that the small balls have time to completely dissolve.
  4. Before giving the suspension to your baby, you need to shake it.

The antibiotic is taken once a day before meals or after, unless the doctor recommends a different frequency of administration. Suprax for children under one year of age is prescribed in an amount of no more than 4 ml per day. Younger preschool children (2-4 years old) are given 5 ml of the drug per day, and small patients from 5 to 11 years old - no more than 10 ml.

Suprax is taken once a day before or after meals

How long does it take to take an antibiotic? The standard duration of therapy is 10 days, in some cases the doctor can reduce it to one week. If you stop giving the antibiotic earlier, some of the bacteria will not die, but will become resistant to the drug. It is important to remember that it is unacceptable to arbitrarily shorten the course of treatment, even if the baby looks healthy.

How to take the pills?

Suprax tablets are taken regardless of meals. You can take the medicine before meals, finish the meal with medicine, or mix the antibiotic with the dish. One pill contains 400 mg of the active substance, so small patients are recommended to dilute only half (200 mg). The latter option is often used in the treatment of children, when a solution is prepared from a tablet, which is subsequently mixed with breast milk and an adapted formula.

The doctor recommends that adults and children weighing over 50 kilograms take 1 antibiotic tablet per day. The dosage can be divided into two doses. For patients whose weight is in the kg range, the recommended dose of the drug is half a tablet (that is, 200 mg) per day. The average duration of the therapeutic course can vary from 1 week to 14 days.

Contraindications and side effects

The use of Suprax is strictly contraindicated for persons who have individual intolerance to any components included in the drug.

Taking Suprax, like almost all antibacterial drugs, is contraindicated for women during pregnancy and breastfeeding. In the first case, the medicine is used extremely rarely - if the life of the expectant mother is in serious danger. If it is necessary to treat a nursing mother, breastfeeding should be stopped. In addition, the use of antibiotics is contraindicated in the treatment of elderly patients, people suffering from colitis and kidney diseases.

Price and analogues of the drug

Suprax is one of the most expensive antibacterial drugs. The national average cost of packaging is about 650 rubles. If you believe the reviews of patients, the antibacterial agent in question justifies its high cost, as it is an effective therapy. If it is not possible to take Suprax, you can pay attention to analogues of the drug - some of them are cheaper.

Sumamed

Sumamed is an antibacterial drug based on azithromycin dihydrate. This medicine is less likely to cause adverse reactions in children, and the course of treatment with Sumamed is shorter in duration than therapy with Suprax. Only a qualified specialist can develop a treatment regimen for a child using this drug. In the form of a suspension, Sumamed can be used to treat babies older than six months. On average, 50 ml of syrup costs 250 rubles.

Pantsef

If there is a need to replace Suprax with a similar broad-spectrum antibacterial agent with an identical active ingredient, the doctor may recommend Pancef. The product has less pronounced side effects and a low likelihood of developing allergies. It can be used in the treatment of children, including infants. However, when treating diseases in babies under six months old, special care should be taken. The average cost of a children's suspension is 570 rubles per 100 ml.

Amoxiclav

In some cases, instead of Suprax, a drug called Amoxiclav is prescribed. This product is based on clavulanic acid and amoxicillin. It is believed that Amoxiclav causes digestive disorders in children more often than Suprax. Children can drink it only on the recommendation of a specialist, and the dosage must be strictly monitored. Patients under 12 years of age are prescribed in the form of a suspension. Its average price is 290 rubles per 100 ml.

My sister was prescribed Suprax for sinusitis. It helped a lot, it got better quickly - already on the third day, but we took the course for all ten days. True, the side effects from it were unpleasant - nausea, constipation, and she felt dizzy.

The doctor recommended Pancef to us, since there are much fewer side effects and the antibiotic costs much less. We took it for 6 days, the baby felt better, I decided that it was not worth giving him such a strong drug for all 9 days, as the doctor prescribed. The child recovered even without it.

Attention! All information on the site is provided for informational purposes only and is for informational purposes only. For all questions regarding the diagnosis and treatment of diseases, you must consult a doctor for an in-person consultation.

Source: http://vseprorebenka.ru/zdorove/preparaty/supraks-instrukciya-po-primeneniyu-dlya-detej-suspenziya.html

Suprax and Suprax Solutab - instructions for use (suspension, tablets, capsules 400 mg). Analogs, reviews about the drug, price

Varieties, names, release forms and composition

Currently, the antibiotic Suprax is available in two varieties, called Suprax and Suprax Solutab. In fact, these two types of the drug differ from each other only in names and forms of release, and there are no more differences between them, since they contain the same active substances, and they also have the same indications, contraindications and rules of use. That is why both Suprax and Suprax Solutab are often combined at the everyday level under one common name “Suprax”. In the further text of the article we will do the same, and by the general name “Suprax” we will mean both varieties of the same drug. We will indicate a specific dosage form and its name only if it is necessary to focus attention on any features of these varieties.

  • Dispersible tablets (under the commercial name Suprax Solutab);
  • Capsules for oral administration (under the commercial name Suprax);
  • Granules for the preparation of an oral suspension (under the commercial name Suprax).

Dispersible (absorbable) tablets are sold under the name "Suprax Solutab", they are oblong, scored on both sides, pale orange in color and have a strawberry scent. Available in packs of 1, 5, 7 or 10 tablets.

Therapeutic effect

Suprax has an antibacterial effect, destroying pathogenic bacteria. It is a broad-spectrum antibiotic because it is destructive to a large number of different types of pathogenic bacteria. The destructive effect of Suprax for bacteria is due to its ability to disrupt the synthesis of the cell wall of pathogenic microbes, without which they simply cannot exist. Along with the destructiveness of Suprax for bacteria, the drug is at the same time safe for the human body, so it can be used to treat children starting from the age of six months.

  • Citrobacter amalonaticus;
  • Citrobacter diversus;
  • Escherichia coli;
  • Haemophilus influenzae;
  • Haemophilus parainfluenzae;
  • Klebsiella pneumoniae;
  • Klebsiella oxytoca;
  • Moraxella (Branhamella) catarrhalis;
  • Morganella morganii;
  • Neisseria gonorrhoeae;
  • Proteus vulgaris;
  • Proteus mirabilis;
  • Pasteurella multocida;
  • Providencia spp.;
  • Streptococcus agalactiae;
  • Streptococcus pneumoniae;
  • Streptococcus pyogenes;
  • Salmonella spp.;
  • Shigella spp.;
  • Serratia marcescens.

The following types of bacteria are resistant to the action of Suprax:

  • Bacteroides fragilis;
  • Clostridium spp.;
  • Enterococcus (Streptococcus) group D;
  • Enterobacter spp.;
  • Listeria monocytogenes;
  • Pseudomonas spp.;
  • Staphylococcus spp.

The effectiveness of taking Suprax once a day for various diseases, according to studies by clinical pharmacologists in Hungary, is as follows:

  • Pneumonia (pneumonia) – 90.9%;
  • Tonsillopharyngitis – 92.6%;
  • Exacerbation of chronic bronchitis – 72.2%;
  • Sinusitis in children – 97.8%;
  • Otitis media in children – 96.0%;
  • Urinary tract infections – 95.0%.

40–50% of the total dose of Suprax taken is absorbed into the systemic circulation, and this amount does not depend on food intake. The antibiotic is excreted within 24 hours in an amount of about 60% of the dose taken. In this case, 50% is excreted unchanged in the urine, and 10% in bile. The remaining 40% of the dose taken is eliminated from the body within a few days.

Indications for use

Suprax and Suprax Solutab are indicated for use in the treatment of the same following infectious and inflammatory diseases of various organs caused by antibiotic-sensitive bacteria:

  • Pharyngitis;
  • Tonsillitis;
  • Sinusitis;
  • Acute and exacerbation of chronic bronchitis;
  • Otitis media;
  • Urinary tract infections (cystitis, urethritis, pyelonephritis, cystourethritis);
  • Gonorrhea;
  • Shigellosis.

Instructions for use

Suprax suspension - instructions for use

Suprax is produced and sold in the form of granules intended for the preparation of a suspension that is taken orally. The finished suspension can be used to treat adults and children older than six months. For young children, the suspension is the optimal dosage form of Suprax.

Also, for the convenience of parents, we provide below a table with dosages of the suspension for children with different body weights, which are valid when using a dosage syringe. This means that if you purchased a bottle with a dosage syringe, you do not have to calculate the dose of the medicine yourself, but use the one already calculated and shown in the table below. It should be remembered that the dosages in the table below are valid only for the dosing syringe, but for the dosing spoon they are different and are shown in the table above.

Suprax 400 (capsules) – instructions for use

Suprax in capsule form can be used to treat adults and adolescents over 12 years of age weighing more than 50 kg. This means that adults over 18 years of age can use the drug without restrictions, and adolescents over 12 years of age can only take Suprax in capsule form if their body weight is more than 50 kg. If a teenager weighs less than 50 kg, then he cannot take Suprax capsules, even if he is over 12 years old. This weight limit applies to adolescents aged 12–18 years.

Suprax Solutab tablets - instructions for use

The tablets are intended for use by adults over 18 years of age and children whose body weight has reached at least 25 kg. This means that adults over 18 years of age can use Suprax Solutab freely, and children can be given the tablets if they weigh 25 kg or more, regardless of their age.

  • Infections of the respiratory tract and ENT organs - the duration of the course of therapy is 7 - 14 days;
  • Tonsillopharyngitis caused by Streptococcus pyogenes - the duration of the course of therapy should be at least 10 days;
  • Uncomplicated gonorrhea - Suprax Solutab is taken only once at a dose of 400 mg (1 tablet);
  • Uncomplicated infections of the lower urinary tract (urethritis) in women - the duration of the course of therapy is 3 – 7 days;
  • Uncomplicated infections of the upper urinary tract (pyelonephritis, cystitis) in women - the duration of the course of therapy is 14 days;
  • Uncomplicated infections of the lower and upper urinary tract in men - the duration of treatment is 1 - 2 weeks.

In general, to determine the duration of the course of therapy, it is recommended to use the following rule: tablets should be taken within 1 to 2 days after the symptoms of infection disappear and/or body temperature normalizes.

special instructions

Tablets, suspension and capsules can be taken regardless of meals.

Use during pregnancy and breastfeeding

During pregnancy, Suprax can be used only if the expected benefit to the woman outweighs all possible risks to the fetus. In practice, cephalosporin antibiotics are often prescribed to pregnant women because they are relatively safe compared to other antibacterial drugs.

Suprax for children

Children under 12 years of age can only be given Suprax in the form of tablets or suspension. Suprax capsules are suitable for use only for children over 12 years of age with a body weight of at least 50 kg. This means that the capsules cannot be taken by children, even if they are over 12 years old but weigh less than 50 kg.

Impact on the ability to operate machinery

Since Suprax can cause side effects from the nervous system (dizziness, tinnitus, etc.), it has a negative effect on psychomotor activity and the ability to control machinery. Therefore, during the entire period of use of the drug, you should refrain from any activities that require a high speed of reactions and concentration.

Overdose

An overdose of Suprax in any dosage form is possible, and is manifested by increased severity of side effects (except allergic reactions). In case of overdose, you should rinse the stomach, take a sorbent (Activated carbon, Polyphepan, Polysorb, etc.) and then, if necessary, carry out symptomatic therapy in intensive care conditions, aimed at maintaining the normal functioning of vital organs and systems. Symptomatic therapy may include the use of glucocorticosteroids (Dexamethasone, Prednisolone, etc.), adrenaline (epinephrine), norepinephrine (norepinephrine), dopamine, as well as oxygen therapy, transfusion of various solutions and artificial ventilation.

Interaction with other drugs

Simultaneous use with tubular secretion blockers (Allopurinol, Probenecid, diuretics (Furosemide, Ethacrynic acid, Tobrasemide, etc.), penicillin antibiotics (Amoxicillin, Ampicillin, etc.), Phenylbutazone, etc.) leads to an increase in the concentration of Suprax in the blood, which may provoke an overdose of the latter.

Side effects

Various dosage forms of Suprax (dispersible tablets, capsules and oral suspension) can cause the following side effects on various organs and systems:

  • Jaundice (yellowing of the skin, sclera of the eyes and mucous membranes);
  • Cholestasis;
  • Hepatitis;
  • Increased levels of bilirubin in the blood (hyperbilirubinemia);
  • Increased alkaline phosphatase activity;
  • Increased activity of liver transaminases (AST and ALT).

4. Blood and hematopoiesis system:

  • Leukopenia (a decrease in the total number of leukocytes in the blood below normal);
  • Neutropenia (a decrease in the number of neutrophils in the blood below normal);
  • Thrombocytopenia (a decrease in the number of platelets in the blood below normal);
  • Pancytopenia (decrease in the total number of red blood cells, white blood cells and platelets in the blood);
  • Blood coagulation disorders and associated bleeding (prolongation of prothrombin time);
  • Agranulocytosis (complete disappearance of basophils, eosinophils, neutrophils from the blood);
  • Hemolytic anemia.

5. Urinary system:

  • Interstitial nephritis;
  • Increased creatinine levels in the blood (creatininemia);
  • Increased urea levels in the blood (uremia);
  • Hematuria (the appearance of blood in the urine);
  • Acute renal failure.

6. Nervous system:

  • Dyspnea;
  • Swelling of the face;
  • Vaginal itching;
  • Vaginitis;
  • Hypovitaminosis B.

If Lyell's syndrome develops, Suprax should be discontinued immediately and consult a doctor as a matter of urgency.

Contraindications for use

Suprax and Suprax Solutab are contraindicated for use if a person has the following conditions or diseases:

  • Individual hypersensitivity or allergic reactions to antibiotics of the cephalosporin and/or penicillin groups;
  • Individual hypersensitivity or allergic reactions to cefixime or any other auxiliary components of the drugs;
  • Chronic renal failure in children under 18 years of age (for Suprax Solutab dispersible tablets);
  • Impaired kidney function, in which creatinine clearance (CC) according to the Rehberg test is less than 60 ml/min (for capsules);
  • The body weight of a child or adult is less than 25 kg (for Suprax Solutab dispersible tablets);
  • Children under 12 years of age (for capsules);
  • Children under six months of age (for granules for the preparation of a suspension for oral administration);
  • Hereditary fructose intolerance, glucose and galactose malabsorption, sucrase and isomaltase deficiency (for granules for oral suspension).

In addition, Suprax in any dosage form (dispersible tablets, capsules and suspension) should be used with caution and under supervision if a person has the following conditions or diseases:

  • Old age (over 65 years old);
  • Chronic renal failure;
  • Pseudomembranous colitis suffered in the past.

Analogs

Currently, Suprax has two types of analogues on the domestic pharmaceutical market - these are synonymous drugs and, in fact, analogues. Synonyms for Suprax are medications that also contain cefixime as an active ingredient. Actually, analogues are drugs that do not contain the same active substance as Suprax, but have the most similar spectrum of therapeutic action. This means that analogues of Suprax are antibiotics belonging to the cephalosporin group (to which Suprax itself belongs).

  • Ixim Lupine powder for the preparation of suspension for oral administration;
  • Panzef granules for the preparation of suspension for oral administration, tablets;
  • Cemidexor tablets;
  • Ceforal Solutab dispersible tablets.

The following antibiotics are analogues of Suprax:

  • Azaran powder for solution for injection;
  • Axone powder for the preparation of solution for injection;
  • Bacperazone powder for the preparation of solution for injection;
  • Bestum powder for the preparation of solution for injection;
  • Betasporin powder for the preparation of solution for injection;
  • Biotriaxone powder for the preparation of solution for injection;
  • Broadsafe-S powder for the preparation of solution for injection;
  • Vicef powder for the preparation of solution for injection;
  • Dardum powder for solution for injection;
  • Intrataxime powder for the preparation of solution for injection;
  • Ificef powder for solution for injection;
  • Kefotex powder for the preparation of solution for injection;
  • Clafobrine powder for the preparation of solution for injection;
  • Klaforan powder for the preparation of solution for injection;
  • Lendacin powder for the preparation of solution for injection and infusion;
  • Lifaxon powder for solution for injection;
  • Liforan powder for the preparation of solution for injection;
  • Lorazidim powder for solution for injection;
  • Loraxone powder for solution for injection;
  • Medaxone powder for solution for injection;
  • Medocef powder for the preparation of solution for injection;
  • Movigip powder for the preparation of solution for injection;
  • Movoperiz powder for the preparation of solution for injection;
  • Operaz powder for the preparation of solution for injection;
  • Orzid powder for the preparation of solution for injection;
  • Oritax powder for the preparation of solution for injection;
  • Oritaxim powder for the preparation of solution for injection;
  • Oframax powder for the preparation of solution for injection;
  • Pactocef powder for the preparation of solution for injection;
  • Resibelact powder for solution for injection;
  • Roceferin powder for solution for injection;
  • Rocephin powder for the preparation of solution for injection and infusion;
  • Sefpotek tablets;
  • Spectracef tablets;
  • Stericef powder for the preparation of solution for injection;
  • Sulzoncef powder for the preparation of solution for injection;
  • Sulmover powder for the preparation of solution for injection;
  • Sulperazon powder for the preparation of solution for injection;
  • Sulperacef powder for the preparation of solution for injection;
  • Sulcef powder for the preparation of solution for injection;
  • Sulcefazone powder for solution for injection;
  • Tax-o-bid powder for the preparation of solution for injection;
  • Talcef powder for the preparation of solution for injection;
  • Tarcefoxime powder for solution for injection;
  • Terzef powder for the preparation of solution for injection;
  • Tizim powder for the preparation of solution for injection;
  • Torocef powder for the preparation of solution for injection;
  • Triaxone powder for solution for injection;
  • Fortazim powder for the preparation of solution for injection;
  • Fortoferin powder for solution for injection;
  • Fortum powder for the preparation of solution for injection;
  • Hizon powder for solution for injection;
  • Cebanex powder for solution for injection;
  • Cedex capsules and powder for the preparation of suspension for oral administration;
  • Ceperon J powder for the preparation of solution for injection;
  • Cetax powder for the preparation of solution for injection;
  • Cephabol powder for solution for injection;
  • Cefaxone powder for solution for injection;
  • Cefantral powder for solution for injection;
  • Cefathrin powder for solution for injection;
  • Cefzide powder for solution for injection;
  • Cefzoxime J powder for solution for injection;
  • Cefobid powder for the preparation of solution for injection;
  • Cefogram powder for the preparation of solution for injection;
  • Cefoperabol powder for the preparation of solution for injection;
  • Cefoperazone powder for solution for injection;
  • Cefoperus powder for solution for injection;
  • Cefosin powder for the preparation of solution for injection;
  • Cefotaxime powder for solution for injection;
  • Cefpar and Cefpar SV powder for the preparation of solution for injection;
  • Cefson powder for the preparation of solution for injection;
  • Ceftazidime powder for solution for injection;
  • Ceftidine powder for solution for injection;
  • Ceftriabole powder for the preparation of solution for injection;
  • Ceftriaxone powder for solution for injection.

Suprax - analogues are cheaper

The following analogue drugs are cheaper than Suprax:

  • Klaforan - price per bottle of powder 160 - 200 rubles;
  • Sulperazon - price per bottle of powder 300 - 400 rubles;
  • Fortum - price per bottle 200 - 600 rubles;
  • Cefaxon - price per bottle 160 - 250 rubles;
  • Cefantral - price per bottle 80 - 120 rubles;
  • Cephobid - price per bottle 300 - 350 rubles;
  • Cefosin - price per bottle 40 - 60 rubles;
  • Cefotaxime produced in Russia, Belarus, Ukraine, China or India - price per bottle is 20 - 40 rubles;
  • Ceftazidime – price per bottle 75 – 160 rubles;
  • Ceftriaxone produced in Russia, Belarus, Ukraine, China or India - price per bottle is 20 - 40 rubles.

Reviews

Most of the reviews about Suprax (from 70 to 80%) are positive, due to its high effectiveness for the treatment of severe, protracted infectious diseases of the respiratory and genitourinary systems, as well as ENT organs in children and adults.

Suprax (Suprax suspension, Suprax 400, Suprax tablets) – price

Currently, the cost of various forms of Suprax and Suprax Solutab in pharmacies in Russian cities varies within the following limits:

  • Suprax, granules for preparing a suspension – 540 – 682 rubles;
  • Suprax, capsules, 6 pieces – 669 – 845 rubles;
  • Suprax Solutab, tablets, 7 pieces – 790 – 1042 rubles.

Author: Nasedkina A.K. Specialist in research of biomedical problems.

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Source: http://www.tiensmed.ru/news/suprax-ab1.html

Suprax: instructions for use for children (suspension)

Suprax, instructions for use for children (suspension) which comes with the medicine, basically contains a semi-synthetic cephalosporin and is used to treat many diseases. It affects gram-positive and gram-negative bacteria, killing them.

Cephalosporins are a type of antibiotic with selective activity against pathogenic microorganisms and are resistant to the action of penicillin.

The Italian scientist Giuseppe Brotz was the first to obtain Cephalosporin from the mold Cephalosporium.

The difference between them and penicillin was their good resistance to beta-lactamase enzymes secreted by microbes. But the structure of the drugs was similar. Therefore, it required improvement. Improved semisynthetic cephalosporins were obtained, developed on the basis of aminocephalosporanic acid. Modified antibiotics kill bacteria and then remove them from the body.

They are most often used in the treatment of osteomyelitis and purulent arthritis, staphylococcal tonsillitis, staphylococcal meningitis, urinary tract infections and others caused by penicillin-resistant species, including against enterobacterial diseases provoked by opportunistic bacteria belonging to the Enterobacteriaceae family. Division by composition and sphere of influence has already been distinguished by five generations of cephalosporins. Suprax belongs to the third generation synthetic cephalosporins, the main active ingredient is cefixime.

It inhibits the defense and integrity of the cell membrane of microbes. Cefixime is stable to the influence of bacterial enzymes aimed at combating Beta-lactam antibiotics produced by gram-positive and gram-negative microbes. Suprax, instructions for use for children (suspension), which must be read before use, is available in dark glass bottles of 60 ml. The drug looks like white or cream-colored granules for preparing a suspension. The product is dissolved in water until the composition becomes a homogeneous consistency.

The prepared suspension is administered orally. It is recommended to shake before each use. The medicinal product is produced together with a dosing spoon (size 5 and 10 ml). Each 5 ml of suspension contains approximately 100 mg of active substance.

Composition of the drug: cefixime trihydrate 1.402 g and sucrose, sodium salt of benzoic acid, gum, strawberry flavor. Inhibits the compound of peptidoglycan, the main structural part of the bacterial cell wall, that is, it suppresses the integrity of the cell wall of the pathogen. Cefixime is stable to the influence of beta-lactamases produced by a predominant number of gram-positive and gram-negative bacteria.

Highly active against pneumococcus, streptococcus, group B streptococcus, Haemophilus influenzae, Moraxella catarrhalis (including species that produce beta-lactamases), Escherichia coli, Proteus miribilis, Gonococcus, Friedlander's bacillus, Klebsiella oxytoca, Salmonella. But most strains of staphylococcus, enterobacter and clostridia, which are not susceptible to cefixime, are resistant to it.

When used orally, the absorption of cefixime reaches 40–50% despite the consumption of food, but the bioavailability of cefixime in serum occurs 0.8 hours faster when taking the drug with food. When consuming the drug in capsule form and at a dose of 200 mg, absorption into serum occurs after 4 hours and amounts to 2 μg/ml, when consumed at a dose of 400 mg - 3.5 μg/ml. The bioavailability of a Suprax suspension at a dose of 200 mg in serum occurs after 4 hours and becomes 2.8 μg/ml, when using a dose of 400 mg - 4.4 μg/ml. About 50% of the dose is excreted in the urine and unchanged per day, 10% of the dose is excreted in bile.

The relationship with plasma proteins, mainly albumin, is 65%. The half-life is determined by the dosage and ranges from 3 to 4 hours. This allows you to use the drug once a day. Applicable to small children.

Large concentrations of Suprax remain in blood serum, bile and urine for a long time. If the patient has renal failure, it is possible to increase the half-life and, as a result, a higher density of the drug in the plasma and slow down its elimination from the body by natural means. In patients with a creatinine clearance rate of 30 ml/min when consuming 400 mg of cefixime, the half-life reaches 7-8 hours, the highest saturation in plasma becomes about 7.53 mcg/ml, and removal in urine per day is −5.5%. The drug Suprax (instructions for use for children) in the form of a suspension is administered orally, that is, through the mouth.

It penetrates tissues and the circulatory system. The full therapeutic effect manifests itself within a few hours after administration - this allows you to take the drug once a day. Suprax, due to its bactericidal effect, penetrates the child’s body and disrupts the synthesis of the cell wall of microorganisms. This drug is special because it is not broken down by gastrointestinal enzymes that produce streptococci, this increases the mechanism of action of the drug.

There is a high susceptibility to various types of bacteria, in particular streptococci, since they are the direct causative agents of infection of the respiratory, urinary, auditory systems, as well as when affecting the skin and subcutaneous fat. A group of bacteria that belong to staphylococci, on the contrary, are not sensitive to this drug.

Suprax for children: indications for use, contraindications and side effects

Young mothers do not need to have Suprax for children in their medicine cabinet, as it is a reserve drug.

This means that it is prescribed only when drugs such as penicillins and macrolides cannot provide a sufficient therapeutic effect.

Suprax is often prescribed to children for acute respiratory and viral diseases of mild to moderate severity. The suspension is used for lesions of the nasal and oral cavities, the middle and internal parts of the auditory system, trachea, bronchi, and inflammatory processes in the tonsils. If respiratory viral infections are not treated promptly, bacterial inflammatory processes occur, that is, a complication. Therefore, it is necessary to prevent the occurrence of complications and be sure to use antibiotic therapy. In case of exacerbation of diseases of the respiratory system, Suprax for children should be prescribed; it effectively fights infection.

If infectious and inflammatory processes occur in the genitourinary system and in the kidneys themselves, you can confidently prescribe a drug. But the drug is prescribed for mild forms of acute cystitis, pyelonephritis, as well as for exacerbation of chronic pyelonephritis. If a child with a severe course of the above diseases is in hospital treatment, then Suprax is used after the end of intravenous or intramuscular administration of cephalosporins.

This fixative stage allows you to reduce the occurrence of relapse of the disease. Medicine knows of cases when the drug should not be offered to a child. This phenomenon cannot be called widespread, but there are contraindications, and they must be followed. Not all young patients are able to tolerate antibiotics of the cephalosporin and penicillin groups. Suprax is not suitable for such children. This category includes babies under six months old and those with chronic liver and kidney diseases.

To prevent the child from developing intestinal dysbiosis and candidiasis, in parallel with the use of Suprax, doctors prescribe drugs that can normalize the intestinal and vaginal microflora, drugs with an antifungal effect such as Acipol and Linex.

If the baby is not yet 6 months old, and there is a persistent need to use Suprax, all possible risks and existing contraindications to taking the medicine must be taken into account. Parents, do not forget that the doctor prescribes an antibiotic when making a diagnosis.

Like any other antibacterial drug, Suprax has side effects. This drug should not be given to a child without a prescription from a qualified specialist. The main side effect is observed in the stomach and intestines. Being an antibiotic, it sharply disrupts the microflora of the stomach and intestines. One of the mechanisms of action is the ability to prevent the development of pathogenic microflora.

Clostridium difficile and candida are those yeast-like fungi that do not express sensitivity to any antibiotic of various groups. If antibiotic therapy is carried out, it is necessary to take probiotics, which protect the microflora of the digestive system. Candida is dangerous for infants, as it leads to candidiasis of the small and large intestines.

It can also move at lightning speed to the child's other systems. But the most dangerous is Clostridium difficile; it causes frequent, incessant diarrhea, which leads to dehydration and damage to the walls of the large intestine. As a result, fluid absorption is impaired and colitis occurs.

Side effects that occur least often are headache, abnormal blood composition, urticaria, decreased appetite, sleep disturbance and dry mouth. Only a doctor has the right to prescribe a Suprax suspension to a child. It is forbidden for parents to use this drug independently. In case of an overdose, a disruption of the digestive system occurs as an increase in the child’s adverse reactions.

In case of overdose it is necessary:

  • rinse the stomach;
  • carrying out symptomatic therapy;
  • carrying out auxiliary therapy to normalize the patient’s condition.

When taking Suprax, false positive urine reactions to glucose may occur.

Suprax for children: dosage and use by age

Suprax is prescribed to children by a doctor. The procedure for use and the dosage volume of the medicine are determined taking into account the original packaging and the age of the patient. The following options for using Suprax are possible.

Granules. The contents of the inverted vessel are shaken vigorously. Then, gradually, 20 g of cooled boiled water is poured into 2 batches. With each manipulation, the resulting composition is shaken. Leave the suspension for 5 minutes.

Shake the mixture before giving it to your child:

  • children from six months to 12 years of age are given medicine at the rate of 8 milligrams per 1 kg of weight once a day or twice during the specified period, 4 mg/kg;
  • for babies under one year old, a dosage of 2.5 to 4 g is provided;
  • two to four year old children take 5 g;
  • for ages 5-11 years, the appropriate dosage is 7-10 g.

The duration of the treatment course is approximately 8-10 full days.

  • Children twelve years old and older absorb 1 tablet (400 mg dose) well in 24 hours, because they weigh more than 50 kilograms;
  • the usual duration of treatment is at least 6–10 days;
  • in the absence of complicated gonorrhea, it is enough to take the medicine once.

Patients on hemodialysis. Patients suffering from malfunction of the kidneys, with CC not exceeding g/min, cannot comply with the standard dosage. Their portion is reduced by 4 times. Cases of peritoneal dialysis with rates less than 20 g per minute allow a twofold reduction in the drug dose.

The period during which the patient should take the medicine is calculated in each individual case. The severity of the disease is taken into account here. Usually a week's course is enough. Infections, which are commonly called Streptococcus pyogenes, are cured in a maximum of 10 days.

How to prepare Suprax for children:

  • The pre-boiled water is cooled.
  • The bubble with granules is shaken sharply.
  • A total of 40 g of water is added in two stages to obtain a homogeneous mass; it is recommended to shake the bottle each time.
  • The prepared product should sit for 5 minutes - this is necessary for the granules to completely dissolve.

Suprax is recommended to be shaken during use. This antibiotic is also well absorbed by juice, compote or breast milk. In a situation where a sick child knows how to eat on his own. The diluted drug is mixed into soup or porridge in compliance with dosage rules.

Suprax is a potent drug, so it can aggressively affect the intestinal microflora. In order to protect the fragile body, the use of probiotics is indicated. This could be Bifidumbacterin or Linex.

Suprax for children: price and popular analogues

Suprax for children, the price of which is the same in all pharmacies, can be replaced with a similar product. An analogue or generic of Suprax should, first of all, be considered as a third-generation cephalosporin and have the main active ingredient cefixime.

How realistic is it to find such a medicine in pharmacies? There will be no difficulties with this. You can ask your pharmacist about this or use an Internet search engine. For example, the drug Ceforal Solutab, which is of Italian origin, contains instructions similar to the description of Suprax. True, its cost is in no way less, and often exceeds, its German counterpart.

Cephalexin has proven itself quite well, for which the buyer will pay an amount that is 7 times less than the cost of Suprax. Perhaps there are cases of its effective use. However, the instructions position it as a first-stream cephalosporin with the main substance - cephalexin, so there is no absolute reason to consider it a full-fledged substitute for Suprax.

But there are other drugs that best meet the standards in relation to substitutes:

  • Cefix - made in Jordan, costs rubles.
  • Chinese Tsemidixor, priced in rubles.
  • Indian drug Ixim Lupine, approximately 400 rubles.
  • Pancef from Macedonia, maximum 350 rubles.

All analogues of Suprax contain the main element - cefixime. The production of these drugs is carried out by different pharmaceutical companies. It is not surprising that the components included in their structures may not be the same, as well as purchasing prices. The main thing is that they guarantee the same effect when applied.

Cefix. Active substance: cefixime. It is considered a bactericidal agent with a multifaceted spectrum of action. The medicine is indicated: for infections of the ENT system, genitourinary tract, respiratory organs, which can be caused by microorganisms or bacteria.

No indications: porphyria, infants up to 6 months (mixture), patients under 12 years (in tablets), if there is a high sensitivity to the constituent elements of the drug.

Pantsef. Main component: also cefixime. It has a reputation as an antibiotic with many functions. Has a bactericidal effect. Recommended: for sinusitis, tonsillitis, otitis media, pharyngitis, gonorrhea without complications, simple diagnoses of the urinary system. Should not be taken: if the body shows hypersensitivity to cephalosporins and penicillins. Adults should be especially careful when giving medicine to babies who are not yet 6 months old.

Ceforal solutab. Cefixime is active. The medicine is recognized as bactericidal. Its effect is aimed at removing or neutralizing infection from the affected organism. There is a beneficial effect of the product on the bulk of gram-negative and gram-positive bacteria. Useful: when the urinary tract and respiratory system are infected, which cause a number of side diseases.

Undesirable: if the body is particularly sensitive to the composition of the drug. The doctor should carefully monitor how the medicine is taken by infants and the elderly. When buying a cheap Solutab substitute, check for the presence of cefixime in it, and its volume in the original must necessarily coincide with the duplicate. When purchasing several packages, do not expect that the cost will necessarily decrease - variations are possible.

Consulting a doctor on the dosage and method of taking the drug will turn out to be an indispensable benefit for you. Patients confirm cases of development of dysbiosis when using Suprax. To avoid unnecessary effects, it is advisable to take probiotics. Doctors evaluate Suprax for children, the price of which is quite high, as an effective drug. It has a powerful effect and is prescribed in special cases.

  • Specialty: Sexopathologist-andrologist, category I
  • Work experience: 29 years
  • Education: Crimean Medical University named after. Georgievsky
  • Place of work: Kherson, City Center for Family Planning, Sexology and Human Reproduction
  • Specialty: Urologist
  • Work experience: 16 years
  • Education: Moscow Medical Academy named after. THEM. Sechenov
  • Place of work: Multidisciplinary medical center “IQ-CLINIC”, Moscow
  • Specialty: Andrologist
  • Work experience: 15 years
  • Education: Kirov State Medical Academy
  • Place of work: Polyclinic of the Research Institute of Physico-Chemical Medicine, Moscow

Source: http://impotencija.net/preparaty/supraks-instrukcija-po-primeneniju-dlja-detej-suspenzija/