Oka remedy

Posted on by admin

Oka remedy

Use the site search:

Instructions for use:

Prices in online pharmacies:

OKIs are nonsteroidal anti-inflammatory and antirheumatic drugs used in the treatment of diseases of the musculoskeletal system.

Table of contents:

OCI solution for topical use is a dental preparation used in the treatment of diseases of the oral cavity.

Pharmacological action of OKI

OCI medications inhibit the synthesis of prostaglandins, due to the ability to inhibit COX-1 and COX-2, have antipyretic, anti-inflammatory and analgesic effects, have anti-bradykinin activity, delay the release of enzymes from lysosomal membranes and stabilize them, which contributes to tissue destruction in chronic inflammation, reduce the release of cytokines and inhibit the activity of neutrophils.

OCI solution, intended for the treatment of diseases of the oral cavity, does not have an antibacterial effect.

OKI release form

According to the instructions, OKIs intended for the treatment of diseases of the musculoskeletal system are produced in the form of:

  • White or pale yellow granules for the preparation of a solution for oral administration, with a characteristic mint odor, in 2 g three-layer double-volume bags, in cardboard packs of 12 and 20 pcs. One packet of OKI granules contains 80 mg of ketoprofen lysine salt, 1.7 g of mannitol, 132 mg of sodium chloride, 3 mg of colloidal silicon dioxide, 20 mg of ammonium glycerate, 20 mg of polyvinylpyrrolidone, 15 mg of sodium saccharinate and 30 mg of mint flavor;
  • White or light yellow rectal suppositories, torpedo-shaped, in two strips of 5 pcs., in cardboard packs. One suppository contains 160 mg of ketoprofen lysine salt and 1.64 g of semi-synthetic glycerides;
  • White or light yellow rectal suppositories for children, torpedo-shaped, in two strips of 5 pcs., in cardboard packs. One suppository contains 60 mg of ketoprofen lysine salt and semi-synthetic glycerides.

OCI for the treatment of oral diseases is produced in the form of a transparent green solution with a characteristic mint odor, in 150 ml plastic bottles with a 2 ml injection dispenser, with a dosing glass, in cardboard packs. One ml of OKI solution contains 16 mg of ketoprofen lysine salt, 200 mg of glycerol, 0.05 mg of ethanol, 1.5 mg of methyl parahydroxybenzoate, 3 mg of mint flavor, 0.7 mg of menthol, 2 mg of sodium saccharinate, 0.16 mg of brilliant green antiseptic , 22 mg of sodium hydrogen phosphate and 1 ml of purified water.

Analogues of OKI

Analogues of OKI in terms of the active substance are the drugs Arketal Rompharm, Ketonal and Flamax.

Analogues of OCI solution for the treatment of oral diseases based on the active substance are not produced.

Analogs of OKI based on the mechanism of action and belonging to the same pharmacological group include the medications Advil, MIG 400 and Faspik.

Analogs of OCI solution for the treatment of oral diseases according to the mechanism of action and belonging to the same pharmacological group include the medications Kamistad and Halls Max.

Indications for use of OKI

According to the instructions, OKI solution for the treatment of diseases of the oral cavity is prescribed for:

According to the instructions, OCI in granules is intended for the symptomatic treatment of inflammatory processes that are accompanied by pain and increased body temperature (adults), as well as for the relief of postoperative pain and short-term symptomatic treatment of inflammatory processes accompanying diseases of the musculoskeletal system and otitis (children over 6 years).

OKI suppositories are intended for systemic use for osteoarthritis, rheumatoid and gouty arthritis, spondyloarthritis and inflammatory lesions of periarticular tissues in adults, as well as for the relief of postoperative pain and short-term symptomatic treatment of inflammatory processes accompanying diseases of the musculoskeletal system and otitis media in children over 6 years of age.

Method of application of OKI

In accordance with the instructions, OKI in the form of granules is taken dissolved in half a glass of water with meals, 80 mg three times a day, and children from 6 to 14 years old - 40 mg three times a day.

OKI solution for the treatment of diseases of the oral cavity is used diluted in half the glass of drinking water included in the kit: adults - two rinses (1 rinse - 5 injections) per day, children from 6 to 12 years old - one rinse (2 injections), children older 12 years – one rinse (3 injections).

In accordance with the instructions, OKI suppositories are used rectally, moistened before administration: adults and children over 14 years old - 1 pc. twice or thrice a day, for elderly patients - 1 pc. 1-2 times a day, children from 6 to 12 years old with a body weight of more than 30 kg - 1 pc. once or twice a day, children over 12 years old - 1 pc. three times a day.

Contraindications

In accordance with the instructions, OKI in granules and suppositories are contraindicated in aspirin-induced asthma, gastric and duodenal ulcers, ulcerative colitis in the acute phase, Crohn's disease, diverticulitis, chronic renal failure, peptic ulcers, blood clotting disorders and hypersensitivity to the components of the drug. Also, OKI in granules is not prescribed in the third trimester of pregnancy, during lactation and for children under 6 years of age.

With caution, OKI in granules and suppositories is prescribed for arterial hypertension, alcoholism, anemia, alcoholic cirrhosis of the liver, bronchial asthma, dehydration, edema, liver failure, sepsis, diabetes, smoking, chronic heart failure, blood diseases, stomatitis, as well as in I and second trimesters of pregnancy.

In accordance with the instructions, OKI solution for the treatment of diseases of the oral cavity is contraindicated in case of aspirin-induced asthma and hypersensitivity to the components of the drug.

OCI solution is prescribed with caution for blood clotting disorders, Crohn's disease, peptic ulcers, gastric and duodenal ulcers, ulcerative colitis in the acute phase, in the third trimester of pregnancy and lactation, as well as for children under 6 years of age.

Side effects of OKI

The use of OKI granules and suppositories causes side effects from various body systems, namely:

  • Abdominal pain, duodenitis, diarrhea, increased bilirubin levels and liver enzyme activity, esophagitis, gastritis, stomatitis, hepatitis, liver failure and enlarged liver (digestive system);
  • Dizziness, tremors, vertigo, anxiety, mood swings, irritability, hallucinations, blurred vision and general malaise (central nervous system);
  • Urticaria, angioedema and anaphylactoid reactions (allergic reactions);
  • Erythematous exanthema, maculopapular rash and itching (dermatological reactions);
  • Painful urination, swelling, cystitis and hematuria (urinary system);
  • Lymphangitis, leukocytosis, thrombocytopenia, enlarged spleen, thrombocytopenic purpura and vasculitis (hematopoietic system);
  • Bronchospasm, sensation of laryngeal spasm, dyspnea, laryngeal edema, laryngospasm and rhinitis (respiratory system);
  • Hypertension, chest pain, hypotension, tachycardia, peripheral edema and pallor (cardiovascular system).

The use of the solution for the treatment of diseases of the oral cavity OKI, according to reviews, causes itching, burning, exacerbation of hemorrhoids and heaviness in the anorectal area.

Okie gran. d/susp. 80mg 2g n12

OKI granules 80 mg/2 g 12 pcs.

Oki granulate 80 mg granulate for prig. suspensions for oral administration 2g No. 12 bags

OKI suppositories (suppositories) 160 mg 10 pcs.

Oki 160 mg No. 10 rectal suppositories

Oki 160 mg N10 suppositories

Oki district local 16mg/ml 150ml n1

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

The well-known drug Viagra was originally developed for the treatment of arterial hypertension.

Four pieces of dark chocolate contain about two hundred calories. So if you don’t want to gain weight, it’s better not to eat more than two slices a day.

You are more likely to break your neck if you fall off a donkey than if you fall off a horse. Just don't try to refute this statement.

Dentists appeared relatively recently. Back in the 19th century, pulling out diseased teeth was the responsibility of an ordinary hairdresser.

The liver is the heaviest organ in our body. Its average weight is 1.5 kg.

It was previously believed that yawning enriches the body with oxygen. However, this opinion has been refuted. Scientists have proven that yawning cools the brain and improves its performance.

American scientists conducted experiments on mice and came to the conclusion that watermelon juice prevents the development of vascular atherosclerosis. One group of mice drank plain water, and the second group drank watermelon juice. As a result, the vessels of the second group were free of cholesterol plaques.

More than $500 million a year is spent on allergy medications in the United States alone. Do you still believe that a way to finally defeat allergies will be found?

In an effort to get the patient out, doctors often go too far. For example, a certain Charles Jensen in the period from 1954 to 1994. survived more than 900 operations to remove tumors.

The cough medicine “Terpinkod” is one of the top sellers, not at all because of its medicinal properties.

74-year-old Australian resident James Harrison has donated blood about 1,000 times. He has a rare blood type whose antibodies help newborns with severe anemia survive. Thus, the Australian saved about two million children.

There are very interesting medical syndromes, for example, compulsive swallowing of objects. One patient suffering from this mania had 2,500 foreign objects in her stomach.

The highest body temperature was recorded in Willie Jones (USA), who was admitted to the hospital with a temperature of 46.5°C.

The human brain weighs about 2% of the total body weight, but it consumes about 20% of the oxygen entering the blood. This fact makes the human brain extremely susceptible to damage caused by a lack of oxygen.

According to WHO research, talking on a mobile phone for half an hour every day increases the likelihood of developing a brain tumor by 40%.

This issue worries many men: after all, according to statistics in economically developed countries, chronic inflammation of the prostate gland occurs in 80–90% of men.

Source: http://www.neboleem.net/oki.php

Why and how is OKI solution used to rinse the mouth and throat?

OKI solution for rinsing is prescribed exclusively for local use and is used for pain relief, treatment and prevention of inflammatory processes in the oral cavity and pharynx.

The medication is also used to treat various ENT diseases, but in this case it must be taken in conjunction with other medications prescribed by the attending physician.

Composition of the drug

The drug OKI is a transparent green liquid with a mint aroma. Available in plastic bottles with a 150 ml dispenser. The kit includes instructions and a measuring cup that allows you to accurately dose the product during preparation.

The main component is ketoprofen lysine salt (dissolves quickly and does not have a harmful effect on the stomach), which provides the antipyretic, anti-inflammatory and analgesic effect of the drug. The auxiliary components are:

  • ethanol, glycerol and methyl parahydroxybenzoate (preservatives that increase the shelf life of the drug);
  • natural menthol flavoring;
  • sodium saccharinate (sweetener);
  • sodium dihydrogen phosphate (added as an emulsifier);
  • brilliant green (synthetic aniline dye);
  • water.

pharmachologic effect

The therapeutic effect of the drug consists of a direct effect on the inflammatory process or the focus of the disease.

The drug has analgesic, antipyretic and anti-inflammatory effects. It also exhibits an antibradykinin effect, helps delay the release and stabilize enzymes of lysosomal membranes, and reduces the activity of cytokines and neutrophils.

It is worth noting that this solution does not have an antibacterial effect on the oral cavity and throat.

Indications and contraindications

Quite often, OKI solution is used as an anesthetic when performing various dental procedures.

The main purpose of the drug is to relieve acute inflammatory processes and pain in the pharynx and oral cavity resulting from:

  • hypertrophic gingivitis (gum disease, characterized by bleeding and swelling);
  • erosive-ulcerative and herpetic stomatitis;
  • inflammatory processes in the tongue resulting from injuries or exposure to microorganisms (glossitis);
  • acute or chronic laryngitis (inflammation of the vocal cords);
  • diseases of the mucous membrane, as well as lymphoid tissue of the pharynx;
  • inflammation of the tonsils (angina);
  • ulcerative formations of various origins, for example, those that appeared as a result of wearing dentures or with the development of aphthous stomatitis;
  • chronic periodontal disease;
  • dental operations.

This medication is contraindicated for use in the following cases:

  • during pregnancy;
  • in childhood (up to 6 years);
  • during breastfeeding;
  • if you have problems with blood clotting;
  • hypersensitivity to the substance ketoprofen;
  • stomach ulcers.

Preparation of the solution, application and dosage regimen

To prepare a rinse solution, you need to boil 0.1 liters of water, and then add the OKI drug to it in the following amount:

  • for adults – 10 ml;
  • for children from 6 to 12 years old – 4 ml;
  • for children aged 12 years and older – 6 ml.

During the day, you need to rinse your throat and mouth twice with the resulting solution (preferably after eating and thoroughly brushing your teeth).

The course of therapy lasts on average 3–4 days. If during this time a positive effect is not observed, then you need to contact a specialist.

Features of application and special instructions

OKI solution is intended for local use only; according to the instructions, adults are prescribed the drug 2 rinses per day with 10 ml of solution (no more than five injections per dose).

Adolescents over 12 years of age: 1 rinse per day containing 3 sprays. Children from 6 to 12 years old - 1 rinse per day (2 sprays).

Reducing the dose of the drug is recommended for the treatment of:

  • elderly patients;
  • patients with functional disorders of the kidneys or liver;
  • patients suffering from bronchial asthma.

Accidental ingestion of the solution does not pose a potential danger to the patient, since the amount of the active substance in the solution does not exceed the dose recommended for oral administration.

Without a doctor's prescription, the medicine can be taken for no more than five days. During the treatment period, it is recommended to refrain from activities related to the need for concentration or a rapid psychomotor reaction.

The use of the drug by patients suffering from chronic liver diseases is indicated only under the close supervision of a specialist. Using the solution may mask signs of an infectious disease.

Side effects

The use of the drug in the form of a solution may cause the following side effects:

  • Gastrointestinal tract - indigestion, nausea, pain in the abdominal area;
  • respiratory system - laryngospasms, spasms or swelling of the larynx;
  • liver – increased bilirubin levels, increased activity of liver transaminases;
  • allergic reactions - itching, swelling of the oral mucosa and throat;
  • local manifestations – burning, itching, exacerbation of hemorrhoids.

No cases of overdose were observed. If any adverse reactions occur after taking the drug, you should immediately inform your doctor.

Opinion of doctors and patients

The point of view of practicing professionals and reviews of patients who used OKI solution for rinsing for therapeutic and preventive purposes.

I have been prescribing OCI solution to my patients for several years now. When properly prescribed and used, the medicine gives excellent results. After 2-3 days of use, cough, sore throat, sore throat, and swelling of the mucous membranes practically go away. In practice, I have not observed any cases of overdose; side effects are very rare. I think the only disadvantage of the drug is the cost, since not all patients can afford to take it.

Olga Ivanovna, therapist

I first learned about this solution when I became seriously ill with a sore throat. Due to severe inflammation of the throat, it was difficult to breathe, I could neither sleep nor eat. I gargled with a solution in parallel with taking antibiotics. I noticed a positive effect immediately. Within one day of taking it, the swelling went down and I began to feel much better. I didn't notice any side effects. Now this drug is always in our first aid kit.

After installing the dentures, I began to experience very severe irritation of my gums. The prosthesis squeezed and rubbed my jaw. The dentist advised me to rinse my mouth with OKI solution. I am very pleased with the result, since the drug relieved pain and irritation literally before our eyes.

What can be replaced?

This medicine has no 100% analogues in terms of its purpose and composition. Among the drugs with a similar active ingredient are Flamax, Artrum and Ketonal. However, all of them are intended for oral use or injection.

Analogues of the drug according to the pharmacological group and direction of action - Faspik and Advil. For the treatment of inflammatory processes in the oral cavity, OCI solution is often replaced by Kamistad and Halls Max.

popular about dentistry.

Copying of materials is permitted only with indication of the original source.

Join us and follow the news on social networks

Source: http://dentazone.ru/preparaty-oborudovanie/medicamenty/rastvor-oki.html

Oka anti-inflammatory solution for rinsing

Pain and inflammation of the mucous membrane are the most unpleasant symptoms accompanying dental diseases. It is impossible to talk, eat, or perform hygiene procedures. You can get rid of them using Oka rinse solution.

Instructions ↑

Rinse solution is one of the Oki series products from the leading Italian concern Dompe.

It is approved for use in EU countries and registered in Russia.

Compound

The active ingredient of the solution is ketoprofen lysine salt.

Ketoprofen is a widely used non-steroidal anti-inflammatory drug (NSAID).

It has long been successfully used to treat inflammation, rheumatism and as an analgesic. For example, it is he who is part of Bystrumgel and Fastumgel.

Photo: Oki - rinse solution

Lysine is an amino acid that actively interacts with ketoprofen to form a stable water-soluble salt. 1 ml of solution contains 16 mg of ketoprofen lysine salt. Unlike ketoprofen, this compound dissolves faster and does not have a pronounced negative effect on the stomach.

The composition includes as excipients:

  • glycerol, as a preservative and to give a thicker consistency,
  • ethanol as a preservative
  • methyl parahydroxybenzoate, as a preservative,
  • mint flavoring,
  • menthol, to give a minty taste and a slight cooling effect,
  • sodium saccharinate as a sweetener,
  • brilliant green, as a dye,
  • sodium dihydrogen phosphate - emulsifier,
  • purified water.

The solution is transparent, light turquoise in color, with a pleasant mint smell. It is produced in a 150 ml plastic bottle with a dispenser and a measuring cap. The dispenser allows you to inject 2 ml of liquid in 1 press.

Action

Oka solution is a local anti-inflammatory drug.

It is used for the symptomatic treatment of inflammation and irritation and has an analgesic effect. When rinsing, only a small amount of ketoprofen enters the bloodstream, and it does not have a systemic effect.

It should be remembered that this solution is only an anti-inflammatory and analgesic agent. It does not have antiseptic or antibacterial properties.

To combat infections and pathogenic microflora, it is necessary to additionally use gels or solutions based on chlorhexidine or metronidazole.

Indications and contraindications

Instructions for use recommend the use of Oka to reduce pain and relieve inflammation when:

  • stomatitis,
  • gingivitis,
  • periodontitis,
  • glossite,
  • periodontal disease,
  • tooth extraction,
  • operations on the mucous membrane,
  • ulcers and bedsores associated with wearing dentures.

In addition to dentistry, it is widely used in the complex treatment of sore throats, laryngitis, tonsillitis, pharyngitis for gargling. It relieves swelling of the larynx and, in combination with antibiotics, speeds up recovery.

It is contraindicated in the following cases:

  • increased individual sensitivity to ketoprofen or any of the auxiliary components,
  • allergic reactions to other NSAIDs in the form of urticaria, rhinitis, aspirin asthma,
  • pregnancy, especially in the third trimester,
  • breast-feeding,
  • bronchial asthma (consultation with a doctor is required),
  • age up to 6 years.

The drug should be used with caution for gastric ulcers, colitis, Crohn's disease, hemophilia and other bleeding disorders.

Dosage, route of administration and duration of treatment

Oka solution is used to rinse the mouth and throat. Adults are recommended to use Oki for rinsing 2 times a day, diluting 10 ml of liquid in 100 ml of water.

For adolescents over 12 years of age, the dosage is reduced to 6 ml of liquid from a bottle per 100 ml of water; for children from 6 to 12 years old, 4 ml of Oka is sufficient. Children and teenagers should also rinse their mouth and throat 2 times a day. A convenient dispenser makes preparing the solution simple and helps you maintain the dosage.

Like all NSAIDs, Oki is not intended for long-term treatment. If the inflammation does not go away within a few days, you should consult a doctor.

Are you afraid of pain during dental treatment? Read reviews of ultracaine in dentistry in this article.

Side effects and overdose

To date, no interactions with other medicinal substances have been identified.

However, if you are using other NSAIDs, such as Nimesil for back pain or MIG for headaches, tell your doctor. Adverse reactions in the form of allergic manifestations are possible. There have been no reports of overdose.

Use during pregnancy and breastfeeding

The solution cannot be used during pregnancy. The use of this product is also not recommended during breastfeeding.

If absolutely necessary, it can be used by stopping feeding for the period of treatment.

Preparation of the solution

Before use, the dispenser spout is moved to the “open” position. To prepare the solution, according to the instructions for use, pour 100 ml of water into the measuring cap and inject 10 ml of liquid from the bottle (5 presses).

Rinse twice a day after brushing your teeth. The solution has a pleasant mint taste with a slightly cooling effect.

Reviews

Reviews about the solution are extremely positive.

Patients note a quick, almost immediate analgesic effect, a noticeable reduction in inflammation of the mucous membranes and relief from sore throats and pharyngitis. Many say that after the first use of Oka, they made this drug an indispensable element of the home first aid kit.

I had a wisdom tooth with very crooked roots removed. The doctor immediately warned that when the anesthesia wears off, it will hurt, and advised Oka’s solution. I don’t like taking extra medications, but for the first few days it was the only thing that saved me. It was possible to sleep peacefully that night. In addition, the advantage over tablets is that you do not need to swallow the solution, and it does not affect the body as a whole.

The first time I learned about Oki was when my son got a sore throat. He could neither eat nor drink, and the doctor prescribed a rinse solution along with antibiotics. It is not used in small children, but my son was 8 years old at that time, so it suited us. I was worried that my picky guy wouldn’t want to gargle if the medicine tasted bad.

It turned out to be in vain. My son said that the solution tasted like toothpaste. The swelling decreased before our eyes, and the son was finally able to eat. I treated my husband with the help of Oka for an exacerbation of chronic pharyngitis. Now I always keep it in my home medicine cabinet just in case.

I can’t imagine how I ever managed without it! I have periodontal disease, and my gums periodically become inflamed and bleed. Oki is simply a salvation in such cases. As soon as you rinse your mouth, the pain goes away, and the inflammation noticeably decreases. It’s a pity that it can only be used for a few days, but during seasonal exacerbations it is very helpful.

I have only positive impressions from him. I changed my dentures, and despite all the adjustments, they put terrible pressure and rubbed my gums at first. She saved herself with ointments and painkillers. I am a pensioner and take a lot of medications, so I wanted something more gentle.

On the advice of the pharmacist, I bought the Oka rinse solution for almost 300 rubles. It is very convenient to dilute, you just need to pour it into a glass of water and spritz it a few times. I had no side effects from Oka, and it relieved irritation very well.

Frequently asked questions ↑

Are there any analogues?

Currently, not a single drug with the same active ingredient in the form of a rinse solution is registered in the Russian Federation.

How to use in children?

Oki can be used only in children over 6 years of age and only if the child knows how to rinse his mouth and spit, and not swallow the liquid.

For children from 6 to 12 years old, measure 4 ml of liquid from the bottle per 100 ml of water using 2 injections into the measuring cap. Rinse your mouth for several minutes 2 times a day. For adolescents over 12 years of age, the dosage is increased to 6 ml (3 injections).

Looking for reviews of Sensodyne toothpaste? Read this article.

How are teeth numbered in dentistry? See drawings and diagrams here.

Prices for the solution ↑

In pharmacies in Moscow and the region, the price for a solution from the Italian concern Dompe ranges from 270–365 rubles per 150 ml bottle.

Did you like the article? Subscribe to site updates via RSS, or follow updates on VKontakte, Odnoklassniki, Facebook, Google Plus or Twitter.

Tell your friends! Share this article with your friends on your favorite social network using the buttons in the panel on the left. Thank you!

Tel.

Read more in Medicines
Ultracaine in dentistry

Ultracaine is a modern remedy for local anesthesia. Widely used in dentistry due to the rapid achievement of an anesthetic effect upon administration.

Hexoral for children

Hexoral is an effective modern local antiseptic drug, very often prescribed for the treatment of various dental and ENT diseases in children. Special.

Uses of sage herb

Since ancient times, sage has been valued as a cure for all diseases; Egyptian healers believed that it could prolong life and does help.

Antibiotics for flux

The appearance of flux in the mouth is accompanied by severe pain and swelling of the cheek. If the disease is not treated, it can lead to serious complications. In therapy.

Source: http://zubzone.ru/preparaty/rastvor-oki-dlja-poloskanija.html

Oka remedy

Instructions for use:

Prices in online pharmacies:

OCI is a non-steroidal anti-inflammatory drug (NSAID).

Release form and composition

  • Rectal suppositories: torpedo-shaped, from white to light yellow (5 pieces in strips, 2 strips in a cardboard pack);
  • Solution for topical use: green, transparent, with a characteristic smell of mint (150 ml in plastic bottles equipped with an injection dispenser (2 ml), in a cardboard pack 1 bottle complete with a dosage cup);
  • Granules for preparing a solution for oral administration: white to pale yellow in color, have a characteristic mint odor (2 g each in three-layer double-volume sachets, 12 or 20 sachets in a cardboard pack).

The active substance of the drug is ketoprofen lysine salt:

  • 1 suppository – 60 or 160 mg;
  • 1 ml of solution – 16 mg;
  • 1 packet of granules – 80 mg.
  • Suppositories: semi-synthetic glycerides;
  • Solution for topical use: glycerol, sodium saccharinate, methyl parahydroxybenzoate, ethanol, sodium hydrogen phosphate, purified water, menthol, brilliant green, mint flavor;
  • Granules: colloidal silicon dioxide, sodium saccharinate, polyvinylpyrrolidone, sodium chloride, mannitol, ammonium glycerate, mint flavor.

Indications for use

Symptomatic treatment of inflammatory processes accompanied by pain and fever, including:

  • Inflammatory diseases of the upper respiratory tract in adults and children over 6 years of age;
  • Rheumatic and inflammatory diseases of the joints, such as osteoarthritis, spondyloarthritis, gouty arthritis, inflammation of the periarticular tissues, rheumatoid arthritis in adults and children over 6 years of age;
  • Relief of postoperative pain in children over 6 years of age.

Solution for topical use

  • Symptomatic treatment of inflammatory diseases of the oral cavity, larynx and pharynx, including glossitis, gingivitis, stomatitis, laryngitis, tonsillitis, pharyngitis, periodontopathy, chronic periodontal disease, aphthae;
  • Analgesia during dental procedures.

Granules for preparation of suspension for oral administration

  • Symptomatic treatment of inflammatory processes accompanied by pain and fever in adults and children over 6 years of age;
  • Relief of postoperative pain in children over 6 years of age.

Contraindications

For all dosage forms:

  • Aspirin triad;
  • Hypersensitivity to the components of the drug or other NSAIDs.

Additionally for rectal suppositories and granules:

  • Ulcerative colitis in the acute phase;
  • Peptic ulcer of the stomach and duodenum in the acute phase;
  • Peptic ulcer;
  • Diverticulitis;
  • Crohn's disease;
  • Blood clotting disorders (including hemophilia);
  • Severe renal dysfunction;
  • Chronic renal failure;
  • Children under 6 years of age;
  • III trimester of pregnancy;
  • Lactation.

Rectal suppositories and granules are prescribed with caution in the following cases:

  • Anemia;
  • Bronchial asthma;
  • Hyperbilirubinemia;
  • Liver failure;
  • Dehydration;
  • Chronic heart failure;
  • Edema;
  • Sepsis;
  • Diabetes;
  • Alcoholism;
  • Alcoholic cirrhosis of the liver;
  • Tobacco smoking;
  • Glucose-6-phosphate dehydrogenase deficiency;
  • Arterial hypertension;
  • Blood diseases, including leukopenia;
  • Stomatitis;
  • I and II trimesters of pregnancy;
  • Elderly age.

The topical solution is prescribed with caution in the following cases:

  • Peptic ulcer of the stomach and duodenum in the acute stage;
  • Exacerbation of ulcerative colitis;
  • Crohn's disease;
  • Peptic ulcer;
  • Diverticulitis;
  • Hemophilia and other blood clotting disorders;
  • Children under 6 years of age;
  • III trimester of pregnancy;
  • Lactation.

Directions for use and dosage

Adults and adolescents over 14 years of age are prescribed suppositories at a dose of 160 mg - 1 pc. 2-3 times a day. The maximum permissible daily dose is 480 mg (3 suppositories). The suppository should be inserted into the rectum; before use, it is recommended to moisten it with water to avoid burning.

For elderly patients, the daily dose is reduced by 2 times.

Children aged 6-12 years (with a body weight of at least 30 kg) are prescribed suppositories at a dose of 60 mg - 1 pc. 1-2 times a day, for children up to 1-3 times a day. The maximum daily dose is 5 mg/kg.

A dose reduction is required in patients with impaired renal and hepatic function.

Solution for topical use

The drug in this dosage form is used as a rinse 2 times a day.

A single dose (per 1 rinse) for adults is 10 ml of solution (5 sprays), adolescents over 12 years old - 6 ml (3 sprays), children 6-12 years old - 4 ml (2 sprays).

1 injection (one click on the dispenser) corresponds to 2 ml of solution. The rinse solution should be prepared in the glass included in the kit. To do this, you need to fill the glass halfway with drinking water (100 ml), turn the spout towards the “open” sign and inject the drug into the water, pressing the spray nozzle all the way, until the dose prescribed by the doctor is reached.

Granules for oral suspension

A suspension is prepared from the granules, which is taken orally during meals.

To receive 1 full dose (80 mg), you must open one sachet along the line marked “full dose”, ½ dose (40 mg) – along the line marked “half dose”. Pour the contents into a glass half filled with water.

Adults and adolescents over 14 years of age are prescribed 80 mg 3 times a day, children 6-14 years old - 40 mg 3 times a day.

For elderly patients, the dose is determined by the attending physician (usually it is reduced by 2 times).

Side effects

When using OKI in the form of rectal suppositories and granules, the following side effects are possible:

  • From the digestive system: stomatitis, diarrhea, abdominal pain, melena, duodenitis, gastritis, esophagitis, hematomesis, erosive and ulcerative lesions of the gastrointestinal tract, enlarged liver, increased activity of liver enzymes, increased bilirubin levels, hepatitis, liver failure;
  • From the central nervous system: tremor, mood swings, hyperkinesia, anxiety, general malaise, hallucinations, dizziness, irritability, visual impairment;
  • From the urinary system: edema, cystitis, painful urination, hematuria;
  • From the hematopoietic system: decreased prothrombin time, lymphangitis, thrombocytopenia, leukocytosis, thrombocytopenic purpura, leukocytopenia, vasculitis, enlarged spleen;
  • From the cardiovascular system: chest pain, tachycardia, hypotension or hypertension, peripheral edema, syncope, pallor;
  • From the respiratory system: rhinitis, sensation of laryngeal spasm, laryngeal edema, dyspnea, bronchospasm, laryngospasm;
  • Dermatological reactions: maculopapular rash, itching, erythematous exanthema;
  • Allergic reactions: urticaria, anaphylactoid reactions (periorbital edema, pharyngeal edema, swelling of the oral mucosa), erythema multiforme, angioedema;
  • Other: increased sweating, menstrual irregularities, conjunctivitis;
  • Local reactions when used rectally: heaviness, itching and burning in the anorectal area, exacerbation of hemorrhoids.

When using the solution for topical use (as a rinse), allergic reactions are possible. If the drug is swallowed, there is a risk of developing systemic side effects.

special instructions

With long-term treatment, sensitization (increased sensitivity of the body) may develop, which requires discontinuation of the drug and appropriate therapy.

Rectal granules and suppositories

During treatment, it is necessary to periodically monitor the peripheral blood picture, the functional state of the kidneys and liver. Patients with impaired renal and hepatic function require dose reduction and careful monitoring.

Ketoprofen can mask signs of infectious diseases, and in patients with bronchial asthma it can cause an attack of suffocation.

Patients who are indicated for a study to determine 17-ketosteroids must discontinue the drug 48 hours before.

If the condition worsens, treatment should be discontinued.

During the period of use of OKI in the form of suppositories and granules, it is recommended to refrain from performing potentially hazardous types of work that require quick reactions and high concentration of attention.

Drug interactions

Possible interaction reactions when using OKI in the form of granules and rectal suppositories:

  • Uricosuric drugs, antihypertensive drugs, diuretics: their effectiveness decreases;
  • Anticoagulants, antiplatelet agents, fibrinolytics, ethanol: their effect is enhanced;
  • Mineralocorticoids, glucocorticoids, estrogens: their side effects increase;
  • Oral anticoagulants, heparin, thrombolytics, antiplatelet agents, cefamandole, cefoperazone, cefotetan: the risk of bleeding increases;
  • Insulin and oral hypoglycemic drugs: their hypoglycemic effect is enhanced (dose recalculation required);
  • Sodium valproate: platelet aggregation is impaired;
  • Nifedipine, verapamil, methotrexate, lithium: their concentration in plasma increases;
  • Non-steroidal anti-inflammatory drugs, glucocorticosteroids, ethanol, corticotropin: the risk of ulcers, gastrointestinal bleeding and renal dysfunction increases;
  • Inducers of microsomal oxidation in the liver (rifampicin, flumecinol, phenylbutazone, phenytoin, tricyclic antidepressants, barbiturates, ethanol): the metabolism of ketoprofen increases;
  • Antacids and cholestyramine: absorption of ketoprofen is reduced.

No drug interactions have been identified with OKI in the form of a solution for topical use.

Terms and conditions of storage

Store at temperatures up to 25 ºС out of the reach of children.

The shelf life of solution granules for topical use is 2 years, rectal suppositories for adults (160 mg) are 5 years, rectal suppositories for children (60 mg) are 3 years.

Found an error in the text? Select it and press Ctrl + Enter.

Okie gran. d/susp. 80mg 2g n12

OKI granules 80 mg/2 g 12 pcs.

Oki granulate 80 mg granulate for prig. suspensions for oral administration 2g No. 12 bags

OKI suppositories (suppositories) 160 mg 10 pcs.

Oki 160 mg No. 10 rectal suppositories

Oki 160 mg N10 suppositories

Oki district local 16mg/ml 150ml n1

Lazolvan is a mucolytic and expectorant drug. Form c. more details

Diazolin is an antihistamine drug belonging to the group. more details

Gelomirtol is a drug used for... more details

Atoxil is a medicine that has a bacteriostatic effect on wounds. more details

Amiksin is an antiviral and immunostimulating drug. F. more details

Lincomycin is a drug with an antibacterial effect. Form . more details

Medical reference book spravka03.net © 2018

When using materials from the site, the active reference is obligatory

Source: http://spravka03.net/oki.html

Oka remedy

Interesting fact: Only humans and dogs can get prostatitis.

Interesting fact: In the human brain, chemical reactions occur in one second.

Interesting fact: In 2002, Romanian surgeons set a new medical record by removing 831 stones from a patient's gallbladder.

Interesting fact: Diabetes ceased to be a deadly disease only in 1922, when insulin was discovered by two Canadian scientists.

Interesting fact: A person can go longer without food than without sleep.

Interesting fact: Three quarters of the bacterial species living in the human intestine have not yet been discovered.

Interesting fact: The human nose is a personal air conditioning system. It heats cold air, cools hot air, and traps dust and foreign bodies.

Interesting fact: A person's finger bends about 25 million times in a lifetime.

Interesting fact: Children whose fathers smoke are 4 times more likely to get leukemia.

Fun fact: Babies are born with 300 bones, but this number drops to 206 by adulthood.

Interesting fact: The Egyptian pharaohs used leeches; in ancient Egypt, researchers found images of leeches carved on stones, as well as scenes of their treatment.

Interesting fact: The weight of the heart at the age of 20–40 years on average reaches 300 g in men, 270 g in women.

Interesting fact: The heaviest human organ is the skin. In an adult of average build, it weighs about 2.7 kg.

Interesting fact: The human brain is as active during sleep as it is during wakefulness. At night, the brain processes and integrates the experiences of the day, decides what to remember and what to forget.

Interesting fact: The liver breaks down alcohol most effectively between 6 and 8 p.m.

Water requirement calculator

Calories burned calculator

Instructions for use:

Price in online pharmacies:

OKI is an antipyretic, analgesic, non-steroidal anti-inflammatory drug.

Active substance

Release form

OKI is available in the form of granules for the preparation of a solution for oral use, rectal suppositories (for adults and children) and a solution for topical use.

Granules are sold in two-volume packaging made of three-layer material with a volume of 2 g (half the dose - 1 g), which are placed in cardboard packs of 12 or 20 pieces.

Rectal suppositories are sold in strips (5 suppositories each), placed in cardboard packages of 2 pcs.

The solution is sold in glass bottles (150 ml each), with a transparent plastic cup for diluting the drug and a dispenser for injecting 2 ml of the drug. Bottles are placed in cardboard packages of 1 piece.

Compound

Ketoprofen lysine salt

Excipients: sodium chloride, mannitol, ammonium glycerate, sodium saccharin, PVP, colloidal silicon dioxide, mint flavor.

Ketoprofen lysine salt

60 mg (for children)

160 mg (adults)

Excipients: semi-synthetic glycerides.

Ketoprofen lysine salt

Excipients: ethanol, glycerol, mint flavor, methyl p-hydroxybenzoate, sodium saccharin, menthol, sodium hydrogen phosphate, verde chertosa (brilliant green), purified water.

Indications

The indication for prescribing the drug (for adult patients) in the form of granules and rectal suppositories is the symptomatic treatment of inflammatory processes accompanied by pain and fever, including rheumatic and inflammatory diseases of the joints:

  • Gouty arthritis.
  • Rheumatoid arthritis.
  • Inflammatory diseases of periarticular tissues.
  • Osteoarthritis.
  • Spondyloarthritis.

For children (over 6 years of age), the drug is prescribed for short-term symptomatic treatment of painful inflammatory processes in the following conditions:

  • Relief of postoperative pain.
  • Pathologies of the musculoskeletal system.
  • Otitis.

The indication for prescribing the drug in the form of a solution is the symptomatic treatment of inflammatory diseases of the oral cavity and ENT organs:

  • Laryngitis.
  • Pharyngitis.
  • Tonsillitis.
  • Angina.
  • Stomatitis.
  • Glossitis.
  • Gingivitis.
  • Periodontopathy.
  • Aphthae.
  • Chronic periodontal disease.
  • Dental procedures (as an analgesic).

Contraindications

General (for all dosage forms) contraindications to the prescription of the drug are:

  • Aspirin asthma.
  • Increased individual sensitivity (including to other NSAIDs).

General contraindications for rectal suppositories and granules are:

  • Crohn's disease.
  • Chronic renal failure.
  • Ulcerative colitis in the acute stage.
  • Peptic ulcer of the duodenum and stomach (in the acute stage).
  • Peptic ulcer.
  • Hemophilia and other bleeding disorders.
  • Diverticulitis.
  • The period of pregnancy (in particular, the third trimester) and breastfeeding.
  • Children's age up to 6 years.

The drug in this dosage form is prescribed with extreme caution for: bronchial asthma, anemia, diabetes mellitus, hyperbilirubinemia, sepsis, dehydration, liver failure, edema, chronic heart failure, arterial hypertension, stomatitis, glucose-6-phosphate dehydrogenase deficiency, blood diseases ( including leukopenia). OCI is also used with extreme caution in alcoholism, pregnancy (I, II trimesters), alcoholic cirrhosis of the liver, smoking, and in elderly patients.

A solution for topical use is prescribed with extreme caution for: Crohn's disease, exacerbations of duodenal and gastric ulcers, exacerbation of ulcerative colitis, peptic ulcers, diverticulitis, chronic renal failure, hemophilia and other bleeding disorders, pregnancy (in particular, the third trimester) and breastfeeding, childhood (up to 6 years).

Instructions for use (method and dosage)

The granules are intended for oral use. Adults - dissolve the contents of 1 two-volume sachet in ½ glass of drinking water and take orally with meals (3 times a day). To receive one full dose of the drug (80 mg), the double sachet must be opened along the line marked “full dose”.

For elderly patients, the optimal dose of OKI is determined by the doctor (it is advisable to reduce the dosage by 2 times).

Children aged 6–14 years: dissolve the contents of 1/2 two-volume sachet in ½ glass of drinking water and take orally with meals (3 times a day). To receive half the dose of the drug (40 mg), the double sachet should be opened along the line marked “half dose”. The optimal dosage of OCI for children aged 14–18 years corresponds to that for adults

Suppositories. The recommended dosage of the drug is:

  • Children aged 6–12 years (body weight more than 30 kg) - 60 mg of the drug (1 sup.) 1–2 times a day.
  • Children over 12 years old - 60 mg of the drug (1 sup.) up to 3 times a day.

In this case, the daily dose of OKI should be no more than 5 mg/kg body weight. Also, the drug should not be used for more than 5 days without consulting a doctor.

Adult patients are prescribed 1 supp. 2–3 times a day. The maximum daily dose is 480 mg. In elderly patients, no more than 2 supp. should be used. in a day.

Solution. The drug in this dosage form is intended for local use. Directions for use: 2 rinses per day, 10 ml of solution (5 injections) per dose.

Adolescents over 12 years of age are allowed to use no more than 3 sprays per cup.

Side effects

The use of the drug in the form of rectal suppositories and granules can provoke the following adverse reactions:

  • Central nervous system: vertigo, tremor, hyperkinesia, irritability, dizziness, mood swings, hallucinations, anxiety, general malaise.
  • Cardiovascular system: tachycardia, pallor, hypotension, hypertension, chest pain, peripheral edema, syncope.
  • Gastrointestinal tract: duodenitis, diarrhea, gastritis, erosive and ulcerative lesions of the gastrointestinal tract, abdominal pain, melena, esophagitis, hematomesis, stomatitis.
  • Genitourinary system: hematuria, edema, cystitis, menstrual irregularities, painful urination.
  • Respiratory system: sensation of laryngeal spasm, rhinitis, laryngospasm, bronchospasm, laryngeal edema, dyspnea.
  • Hematopoietic organs: lymphangitis, purpura, decreased PV, thrombocytopenia, leukocytosis, leukocytopenia, vasculitis, enlarged spleen, thrombocytopenic purpura.
  • Sense organs: blurred vision, conjunctivitis.
  • Liver: increased activity of liver transaminases and bilirubin levels, increased liver size, liver failure, hepatitis.
  • Skin: erythematous exanthema, urticaria, maculopapular exanthema, angioedema, increased sweating, itching, exudative erythema multiforme (including Stevens-Johnson syndrome).
  • Allergic manifestations: swelling of the oral and pharyngeal mucosa, anaphylactoid reactions, periorbital edema.

Any other side effects not listed in this instruction should be reported to your doctor. If undesirable reactions from the intestines occur, OKI in the form of granules must be taken with milk or with meals.

Additionally for rectal suppositories:

  • Local reactions: heaviness in the anorectal area, itching, burning, exacerbation of hemorrhoids.

No cases of drug overdose have been reported to date.

special instructions

In case of functional disorders of the liver and kidneys, careful monitoring of the patient and a reduction in the dose of the drug is necessary. The use of ketoprofen by patients suffering from bronchial asthma can provoke an attack of bronchial asthma.

During therapy, the picture of the functional state of the kidneys and liver, as well as peripheral blood, should be monitored.

The use of ketoprofen may mask the symptoms of an infectious disease.

Women planning a pregnancy should refrain from taking OCI, as the likelihood of egg implantation may decrease.

The dosages used for the treatment of children are not effective enough in the treatment of adult patients.

If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the study.

Accidental ingestion of OKI solution for rinsing does not lead to serious consequences, since a single dose contains 160 mg of active substance, which corresponds to the dose intended for oral use.

Prolonged use of the solution for external use may lead to sensitization. In this case, it is necessary to stop using OKI and select adequate methods of therapy.

During treatment with the drug, it is necessary to refrain from potentially dangerous activities associated with the need for rapid psychomotor reactions and concentration.

Instructions for preparing the solution:

  • Turn the nozzle of the sprayer towards the inscription “open”. This will bring the device into its functional position.
  • By pressing the spray nozzle all the way, inject the drug into the supplied plastic cup (repeat the injections until the dose prescribed by the doctor is reached). By pressing the dispenser-injector once, the patient receives 2 ml of solution.
  • Dilute the injected dose in 100 ml (1/2 cup) drinking water.

Storage conditions and periods

Store at a temperature not exceeding 25 °C. Keep away from children. Shelf life – 5 years.

The description posted on this page is a simplified version of the official version of the annotation for the drug. The information is provided for informational purposes only and does not constitute a guide for self-medication. Before using the medicine, you must consult a specialist and read the instructions approved by the manufacturer.

OKI granules 80 mg/2 g 12 pcs.

Oki granulate 80 mg granulate for prig. suspensions for oral administration 2g No. 12 bags

OKI suppositories (suppositories) 160 mg 10 pcs.

Oki 160 mg No. 10 rectal suppositories

Oki 160 mg N10 suppositories

When using materials from the site, the active reference is obligatory.

The information presented on our website should not be used for self-diagnosis and treatment and cannot serve as a substitute for consultation with a doctor. We warn you about the presence of contraindications. Specialist consultation is required.

Source: http://dolgojit.net/oki.php