Nurofen syrup dosage by weight

Nurofen for children - official instructions for use

on the medical use of the drug NUROFEN FOR CHILDREN

Trade name: NUROFEN® FOR CHILDREN

Registration number: P No/01

International nonproprietary name (INN) ibuprofen

Table of contents:

• Nurofen for children - official instructions for use
• Children's Nurofen - dosage by weight
• What is better to choose to eliminate unpleasant symptoms?
• About use
• How to use correctly
• Dosage of Nurofen according to the child’s weight:
• Comments on the article
• We recommend reading
• how to calculate the dosage of the antipyretic Nurofen?
• Mom won't miss
• Children's syrup Nurofen for pain and temperature: instructions for use for children, indications and precautions
• Composition and packaging
• How does the product work?
• When is it prescribed?
• Special conditions
• Dosage by age and weight
• Contraindications
• Side effects
• Possibility of combination with other medications
• Expiration date and storage rules for the drug
• Average price in Russian pharmacies
• Reviews
• Nurofen for children: will help quickly, safely and effectively
• Information about the drug
• Form and composition
• Indications for use
• How dangerous (and is it dangerous?) is the drug for a child?
• Contraindications
• Side effects
• Dosage regimens, dosage
• Analog drugs
• Nurofen for children
• Release form and composition
• Pharmacological properties
• Pharmacodynamics
• Pharmacokinetics
• Indications for use
• Contraindications
• Instructions for use of Nurofen for children: method and dosage
• Film-coated tablets
• Oral suspension
• Rectal suppositories
• Side effects
• Overdose
• special instructions
• Impact on the ability to drive vehicles and complex mechanisms
• Use during pregnancy and lactation
• Use in childhood
• For impaired renal function
• For liver dysfunction
• Use in old age
• Drug interactions
• Analogs
• Terms and conditions of storage
• Conditions for dispensing from pharmacies
• Reviews of Nurofen for children
• Price for Nurofen for children in pharmacies

Dosage form: oral suspension [orange, strawberry]

Description: a suspension of white or almost white color, syrupy consistency with a characteristic orange or strawberry odor.

5 ml of Nurofen® suspension for children contains 100 mg of ibuprofen (active ingredient) and excipients: maltitol syrup, water, glycerol, citric acid, sodium citrate, sodium chloride, sodium saccharinate, orange flavor 2M16014 or strawberry flavor E, xanthan gum, polysorbate 80, domiphene bromide.

Pharmacotherapeutic group non-steroidal anti-inflammatory drug.

It has analgesic, anti-inflammatory and antipyretic effects. The mechanism of action of ibuprofen is due to inhibition of the biosynthesis of prostaglandins - mediators of pain and inflammation. The effect of the drug lasts up to 8 hours.

Nurofen" for children is used from 3 months of life to 12 years as an antipyretic for acute respiratory diseases, influenza, childhood infections, post-vaccination reactions and other infectious and inflammatory diseases accompanied by an increase in body temperature. The drug is used as an analgesic for pain of mild or moderate intensity, including: headaches and toothaches, migraines, neuralgia, pain in the ears and throat, pain with sprains and other types of pain.

Your doctor may also recommend this drug for other indications (in this case, follow your doctor’s recommendations on dosage and dosage regimen).

Nurofen® for children should not be used if:

Read about how to choose effective and safe laxatives for constipation for children on our website.

You can learn how to cure laryngotrachemitis in a child at home from our other publication.

What to do if your child has severe ear pain? This article will tell you about this.

Contraindications

It is not recommended to use the drug if:

• individual intolerance to ibuprofen or one of the auxiliary drugs of Nurofen syrup;

Side effects

The patient's risk of experiencing one or more side effects is fairly easy to minimize. To do this, you must carefully follow the instructions.

So, if you take Nurofen syrup in minimal doses and for a short course, then the main side effects occur with an overdose.

They are divided into several groups:

• problems with the circulatory and lymphatic systems suggest disruption of hematopoiesis;

Possibility of combination with other medications

When using Nurofen baby syrup together with other means of similar effects, the effect may be enhanced.

At the same time, the simultaneous use of diuretics and antihypertensive drugs helps to reduce the effectiveness of the drug, and side effects may be increased.

Expiration date and storage rules for the drug

Nurofen children's syrup must be stored at temperatures up to 25 degrees. The storage location must be dry.

The shelf life is 3 years. It is strictly forbidden to use expired medicine.

Average price in Russian pharmacies

The average cost of Nurofen baby syrup in Russia may vary depending on the region and pharmacy.

Reviews

It is quite natural that reviews can be both positive and negative.

So, on one of the forums, an unregistered user wrote that his child was intolerant to the drug. After a few minutes, the stomach begins to hurt sharply, and sometimes it can lead to vomiting.

However, Sweet Salvation writes on another forum that Nurofen is almost completely safe for a child, since it can also be taken during pregnancy. She expresses great doubts about other analgesics.

At the end of 2014, Inga Baroeva wrote about Nurofen syrup that she used it to bring down her child’s fever during teething.

I was satisfied with the drug and especially noted the ease of use thanks to the syringe, and the plastic bottle is not afraid of falls. The effect lasts quite a long time, which allows you to see your baby’s smile again. Now Nurofen is always in her medicine cabinet.

If you approach the issue of its use wisely and do not abuse it, then no negative consequences will arise, and the child will feel relief and will again be able to please his parents with his smile.

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Source: http://malutka.pro/preparaty/siropy/nurofen.html

Nurofen for children: will help quickly, safely and effectively

Frequent symptoms that accompany many colds, viruses, infectious diseases, inflammatory processes, as well as the period of teething in a baby are fever, fever, and pain.

Information about the drug

Form and composition

Taking into account the fact that young children usually do not yet know how to swallow tablets, Nurofen is available in the form of a syrup-suspension with orange or strawberry flavor, as well as suppositories, which is very convenient if a sick person has a gag reflex, as well as if it is necessary to reduce the temperature of a sleeping child without disturbing his sleep.

In addition, suppositories act faster than syrup, since the absorption of active substances when administering suppositories occurs directly from the intestines, bypassing the stage of absorption by the stomach.

The main active ingredient of the drug is ibuprofen, a non-hormonal anti-inflammatory substance that has effective analgesic properties and also helps to gently reduce the patient’s temperature.

Ibuprofen suppresses the synthesis of prostaglandins in the body - substances that “intensify” inflammatory processes - and thus “inhibits” the development of inflammation.

Also, numerous studies have established the positive effect of this component on the body’s production of interferon and increasing immune resistance in the fight against infection.

In addition to ibuprofen, Nurofen syrups contain the natural sweetener Maltitol, derived from starch, which does not affect blood sugar levels, does not contribute to the formation of caries and is absolutely safe even for those suffering from diabetes, as well as domiphen bromide, a substance with antiseptic and antifungal properties that enhances the general anti-inflammatory effect drug.

If dosages are observed, Nurofen is one of the safest and most effective medications for lowering fever, reducing pain and inflammation in children.

Its action usually lasts for 8 hours, which is also very convenient - an evening dose will help avoid fever at night and provide the child (and the whole family with him) complete and relaxing rest, which is especially important during illness.

Indications for use

Nurofen syrups and suppositories can be used to treat children from 3 months of age.

The use of the drug should be agreed with the treating pediatrician.

This medicine is prescribed to eliminate febrile conditions, reduce inflammation and pain in acute respiratory, viral and infectious diseases, influenza, otitis, temperature reactions to vaccinations, teething.

Due to the low dosage, Nurofen suppositories are recommended for use in children under 3 years of age.

You can learn about the treatment of pyoderma in children from this article.

How dangerous (and is it dangerous?) is the drug for a child?

Contraindications

The drug should not be used if there are allergic reactions to its components, or with bronchial asthma (may provoke bronchospasm).

In addition, ibuprofen is contraindicated for liver and kidney diseases, peptic ulcers (reduces the production of mucus that “protects” the stomach), and blood clotting disorders (reduces this indicator).

Side effects

If these symptoms occur, you should immediately stop taking Nurofen and consult a doctor.

Dosage regimens, dosage

Each package of Nurofen syrup comes with a special syringe for dosing the medicine with a volume of 5 ml, which corresponds to 100 mg of ibuprofen. Each Nurofen suppository contains 60 mg of ibuprofen.

To determine the correct single dosage, it is necessary to focus on the child’s weight: it is recommended to take it at a rate of 5 to 10 mg per kilogram of the patient’s body weight.

If necessary, this dose can be repeated up to three to four times within 24 hours, but do not forget that the maximum daily dosage of the drug is 30 mg of ibuprofen per kilogram of the child’s weight.

If it is exceeded, toxic phenomena may develop. Based on this, the following doses are usually prescribed:

• children 6-12 months (weighing 6-10 kg): one suppository or 2.5 ml of syrup 3-4 times a day, but not more than 5 ml (three suppositories) per day;
• 1-3 years (10-15kg): 5 ml of syrup up to three times a day or 1 suppository no more than 4 times a day;
• 4-6 years (15-20kg): 7.5 ml of syrup up to three times a day;
• 7-9 years (21-29kg): 10 ml of syrup up to three times a day;
• children (30-40kg): 15 ml of syrup up to three times a day.

This drug should not be used for more than 5 days.

Analog drugs

Similar to Nurofen, the following antipyretic, analgesic and anti-inflammatory drugs can be used to treat a child (if there are no contraindications or allergies):

• Panadol for children - syrup with strawberry flavor (the main active ingredient is paracetamol);

• Cefekon D for children in suppositories in an age-appropriate dosage (paracetamol);
• Ibuklin junior (soluble tablets with mint flavor, children over 3 years old): an effective combination of ibuprofen and paracetamol;
• Efferalgan (suppositories and syrup): base – paracetamol;
• Viburkol (suppositories) is a homeopathic medicine based on plant extracts.

The use of all of these remedies requires consultation with your treating pediatrician.

For viral infections, it is not recommended to “bring down” body temperature below 38.5C, since elevated temperature allows the body to produce interferons to successfully fight the disease.

To avoid cramps and spasms, heart rhythm disturbances and other complications of febrile conditions, it is necessary to reduce body temperature above 38.5-39 C, and Nurofen will help to do this gently, quickly, safely and effectively.

If a newborn has heat rash: what to do? Find the answer to the question in this article.

Source: http://mamaliza.com/zdorove/lekarstva/nurofen.html

Nurofen for children

Nurofen for children: instructions for use and reviews

Latin name: Nurofen for Children

ATX code: M01AE01

Active ingredient: Ibuprofen (Ibuprofen)

Manufacturer: Reckitt Benckiser Healthcare International Ltd. (Great Britain)

Update of description and photo: 11/15/2017

Prices in pharmacies: from 99 rub.

Nurofen for children is an NSAID (non-steroidal anti-inflammatory drug) used in pediatric practice.

Release form and composition

• film-coated tablets: biconvex, round in shape, on one side the inscription Nurofen is printed in black, the shell and core in the cross section are white to almost white (6, 8, 10 or 12 pcs. in blisters, 1 or 2 blisters in a cardboard pack; 10 or 12 pcs in blisters, 3 blisters in a cardboard pack; 12 pcs in blisters, 4 or 8 blisters in a cardboard pack);
• oral suspension (orange/strawberry): a liquid of syrupy consistency, from white to almost white in color, with a characteristic orange/strawberry odor (100, 150 or 200 ml each in polyethylene terephthalate bottles, equipped with a dosing syringe, 1 set in a cardboard box );
• rectal suppositories: torpedo-shaped, glossy, from white to almost white; It is allowed to have a funnel-shaped depression or an air rod on the cut (5 pieces in aluminum blisters, 2 blisters in a cardboard pack).

Composition per 1 tablet:

• active substance: ibuprofen – 200 mg;
• auxiliary ingredients: sodium lauryl sulfate, sodium citrate dihydrate, croscarmellose sodium, stearic acid, colloidal silicon dioxide;
• shell: carmellose sodium, acacia gum, titanium dioxide, sucrose, macrogol 6000, talc;
• black ink Opacode S: shellac, black iron oxide dye (E172), propylene glycol and solvents that evaporate during the printing process (butanol, ethanol, isopropanol, purified water).

Composition per 5 ml suspension:

• active substance: ibuprofen – 100 mg;
• auxiliary ingredients: maltitol syrup, glycerol, polysorbate 80, sodium saccharinate, sodium chloride, sodium citrate, citric acid, xanthan gum, orange flavor 2M16014/strawberryE, domiphene bromide, purified water.

Composition for 1 suppository:

• active substance: ibuprofen – 60 mg;
• auxiliary ingredients: solid fats – vitepsol H15 and vitepsol W45.

Pharmacological properties

Pharmacodynamics

The active ingredient of Nurofen for children is ibuprofen. Like other non-steroidal anti-inflammatory drugs, it specifically relieves pain symptoms and has an anti-inflammatory and antipyretic effect.

Being a non-selective blocker, ibuprofen blocks cyclooxygenase 1 and 2 (COX-1 and COX-2), which inhibits the synthesis of mediators of inflammation, pain and hyperthermic reaction - prostaglandins. In addition, ibuprofen reversibly inhibits platelet aggregation.

The drug has the most pronounced analgesic effect for pain of inflammatory origin; its effect lasts for 8 hours.

Pharmacokinetics

• absorption and distribution: ibuprofen is well absorbed from the gastrointestinal tract (gastrointestinal tract), quickly and almost completely absorbed into the systemic circulation. In blood plasma after administration on an empty stomach, the substance is detected after 15 minutes, and the maximum plasma concentration (Cmax ₎ is reached after 60 minutes. Taking the drug with food can increase the time to reach Cmax _by up to 120 minutes. Up to 90% of ibuprofen binds to blood plasma proteins, as a result of which the substance, slowly penetrating into the joint cavities, lingers for a long time in the synovial fluid, providing it with concentrations higher than in plasma. According to a few studies, ibuprofen penetrates into breast milk in extremely low concentrations;
• metabolism and excretion: up to 60% of the substance in the pharmacologically inactive R-form after absorption is slowly transformed into the active S-form; Ibuprofen is metabolized in the liver; excreted by the kidneys (only less than 1% unchanged), to a lesser extent - with bile. The half-life of the drug is 2 hours.

Indications for use

Nurofen for children, depending on the dosage form, is used to treat patients of different age groups: suppositories are prescribed to children from 3 months to 2 years, a suspension to children from 3 months to 12 years, tablets to children from 6 years of age and adult patients. Nurofen suppositories for children are also recommended to be used if for some reason it is impossible to take oral forms of the drug, or in case of vomiting.

All forms of the drug are used as an analgesic to relieve pain of various origins: headache, dental, ear, sore throat, muscle, menstrual, joint, rheumatic, back pain, neuralgia, migraines and other pathological conditions accompanied by pain.

As an antipyretic drug, Nurofen for children is recommended for the following infectious and inflammatory diseases and conditions accompanied by fever: acute respiratory infections (acute respiratory diseases), influenza, childhood and other infections, post-vaccination reactions.

Nurofen for children is intended only for symptomatic therapy, pain relief and inflammation at the time of its use. The drug does not have a clinically significant effect on the progression of the disease.

Contraindications

Absolute contraindications to the use of Nurofen for children in any of the release forms:

• erosive and ulcerative lesions of the gastrointestinal tract in the acute phase, including ulcerative colitis, peptic ulcer, exacerbation of gastric and duodenal ulcers, Crohn's disease (including history data);
• severe arterial hypertension;
• period after CABG (coronary artery bypass grafting);
• decompensated heart failure;
• syndrome of complete or incomplete intolerance to aspirin (urticaria, polyps of the nasal mucosa, rhinosinusitis, bronchial asthma) and/or other NSAIDs;
• blood diseases (hemophilia, other coagulation disorders, hemorrhagic diathesis, glucose-6-phosphate dehydrogenase deficiency, hypocoagulation);
• severe liver dysfunction;
• severe renal impairment with creatinine clearance (CC) <30 ml/min;
• bleeding (intracranial, from the gastrointestinal tract, etc.);
• III trimester of pregnancy;
• increased individual sensitivity to the active substance or any other components of the drug.

Additional contraindications for tablets:

• diseases of the optic nerve (scotoma, amblyopia, color vision impairment);
• hearing loss, vestibular system disorder;
• breast-feeding;
• age up to 6 years.

Additional contraindications for the suspension:

• fructose intolerance;
• confirmed hyperkalemia;
• child weight up to 5 kg.

Additional contraindications for suppositories:

• proctitis;
• confirmed hyperkalemia;
• child weight up to 6 kg.

Relative contraindications for the use of Nurofen for children (caution is required): simultaneous use with other NSAIDs, a history of gastric ulcers, ulcerative bleeding from the gastrointestinal tract, enteritis, gastritis, colitis, Helicobacter pylori infection, ulcerative colitis; bronchial asthma or allergic diseases in the acute stage, or a history of such (probably the development of bronchospasm), severe somatic diseases, systemic lupus erythematosus or mixed connective tissue disease, so-called. Sharp's syndrome (increases the likelihood of aseptic meningitis), renal failure, including dehydration (with creatinine clearance 30–60 ml/min), fluid retention and edema; liver failure, arterial hypertension/heart failure, diabetes mellitus, cerebrovascular diseases, hyperlipidemia/dyslipidemia, peripheral arterial disease, blood diseases of unknown etiology (anemia, leukopenia), concomitant use with other drugs that can increase the likelihood of ulceration or bleeding, and specifically with GCS (glucocorticosteroids) for oral administration (including prednisolone), anticoagulants (including warfarin), selective serotonin reuptake inhibitors (including fluoxetine, paroxetine, citalopram, sertraline), antiplatelet agents [including acetylsalicylic acid (ASA) and clopidogrel]; I and II trimesters of pregnancy, old age; breastfeeding period - for suspension and suppositories; children aged 6 to 12 years – for tablets.

Instructions for use of Nurofen for children: method and dosage

Film-coated tablets

The tablets are taken orally, after meals, with water.

The recommended dosage of Nurofen for children over 12 years of age and adults, unless otherwise prescribed by a doctor: 200 mg (1 tablet) 3-4 times a day. If it is necessary to achieve a faster therapeutic effect for adult patients, the dose can be increased to 400 mg (2 tablets) 3 times a day.

Children aged 6 to 12 years, weighing more than 20 kg, are recommended to take 1 tablet up to 4 times a day.

The interval between doses of the drug should not be less than 6 hours.

The maximum daily dose is 1200 mg (6 tablets).

If symptoms of the disease persist after taking the tablets for 2-3 days, you must interrupt therapy and consult a doctor.

Oral suspension

The suspension is intended for oral use. In case of increased sensitivity of the gastrointestinal tract, it is recommended to combine the drug with food. Before use, the bottle of suspension should be shaken thoroughly.

Recommended dosage of Nurofen for children depending on the age and weight of the child:

• children from 3 to 6 months, weighing 5–7.6 kg: 50 mg (2.5 ml) 3 times a day; daily dose – 150 mg (7.5 ml);
• children from 6 to 12 months, weighing 7.7–9 kg: 50 mg (2.5 ml) 3–4 times a day; daily dose – 200 mg (10 ml);
• children from 1 year to 3 years, weighing 10–16 kg: 100 mg (5 ml) 3 times a day; daily dose – 300 mg (15 ml);
• children from 4 to 6 years old, weighing 17–20 kg: 150 mg (7.5 ml) 3 times a day; daily dose – 450 mg (22.5 ml);
• children from 7 to 9 years old, weighing 21–30 kg: 200 mg (10 ml) 3 times a day; daily dose – 600 mg (30 ml);
• children from 10 to 12 years old, weighing 31–40 kg: 300 mg (15 ml) 3 times a day; daily dose – 900 mg (45 ml).

The duration of therapy should not be more than 3 days. The indicated dose should not be exceeded.

If symptoms of the disease persist after taking the suspension for 24 hours in children aged 3–5 months, or three days in children aged six months and older, or if they intensify, treatment should be stopped and consult a doctor.

To relieve fever after immunization, children under six months of age are given a single dose of ibuprofen - 50 mg (2.5 ml of suspension); if necessary, after 6 hours you can prescribe a second dose at the same dose.

The maximum daily dose of Nurofen for children is 100 mg (5 ml).

The exact dose of the suspension is measured using a measuring syringe supplied with the bottle (1 ml of suspension contains 20 mg of ibuprofen, respectively, 5 ml - 100 mg).

Rules for using a measuring syringe:

1. The syringe is tightly inserted into the neck of the bottle.
2. The bottle with the inserted syringe is turned upside down, the piston is smoothly pulled down, drawing the suspension to the required level.
3. Return the bottle to its original position, then carefully turn and remove the syringe.
4. Place the syringe in the child’s oral cavity, slowly press the plunger, smoothly releasing the suspension.
5. After the procedure, rinse the syringe with warm water and dry it out of the reach of children.

Rectal suppositories

Nurofen suppositories for children are intended for rectal use.

When treating fever and pain, the dose is calculated based on the child’s age and weight. The maximum daily dose should not be more than 30 mg/kg of the child’s weight, and the intervals between doses should be less than 6–8 hours.

Recommended dose of the drug depending on the age and weight of the child:

• children from 3 to 9 months, weighing 6–8 kg: 1 suppository (60 mg) up to 3 times a day; maximum daily dose – 180 mg;
• children from 9 to 24 months, weighing 8–12 kg: 1 suppository (60 mg) up to 4 times a day; the maximum daily dose is 240 mg.

The duration of therapy should not be more than 3 days. The indicated dose should not be exceeded.

If symptoms of the disease persist after using suppositories for 24 hours in children aged 3–5 months, or 3 days in children aged six months and older, or if they intensify, treatment should be stopped and consult a doctor.

To relieve fever after immunization, children under one year of age are prescribed a single administration of 1 suppository (60 mg); if necessary, after 6 hours you can re-administer the drug in the same dose. More than 2 pcs. (120 mg) should not be used within 24 hours.

Side effects

The likelihood of side effects is reduced to a minimum if you follow the dosage regimen of Nurofen for children and use ibuprofen for the shortest possible course in the minimum effective dose necessary to eliminate the symptoms of the disease.

Side effects recorded with short-term use of ibuprofen in doses not exceeding 1200 mg per day are predominantly dose-dependent (rating scale: very often - ≥ 0.1; often - ≥ 0.01 and < 0.1; infrequently - ≥ 0.001 and < 0.01; rarely - ≥ 0.0001 and < 0.001; extremely rare - < 0.0001; with unknown frequency - insufficient data to make an assessment):

• hematopoietic system: extremely rarely - hematopoietic disorders (leukopenia, anemia, aplastic/hemolytic anemia, pancytopenia, thrombocytopenia, agranulocytosis; the primary signs of such disorders are sore throat, fever, superficial ulcers in the oral cavity, severe weakness, flu-like symptoms, subcutaneous hemorrhages, nosebleeds, bleeding and bruising of unknown origin);
• immune system: uncommon - nonspecific allergic and anaphylactic reactions, respiratory tract responses (bronchial asthma, including its exacerbation, shortness of breath, dyspnea, bronchospasm), skin reactions (urticaria, itching, purpura, Quincke's edema, exfoliative/bullous dermatoses, including toxic epidermal necrolysis, Stevens-Johnson syndrome, Lyell's syndrome, erythema multiforme), eosinophilia, allergic rhinitis; extremely rarely - severe hypersensitivity reactions (including swelling of the tongue, larynx and face), shortness of breath, arterial hypotension, tachycardia (anaphylaxis, Quincke's edema or severe anaphylactic shock);
• Gastrointestinal tract: uncommon – nausea, abdominal pain, dyspepsia; rarely – flatulence, constipation/diarrhea, vomiting; extremely rarely - melena, peptic ulcer, gastritis, hematemesis, perforation or gastrointestinal bleeding, ulcerative stomatitis; with unknown frequency - exacerbation of ulcerative colitis, Crohn's disease;
• liver and biliary tract: extremely rarely - liver function disorders;
• urinary system: extremely rarely - acute renal failure (compensated/decompensated), especially in the case of long-term use, in combination with an increase in urea content in the blood plasma and swelling, papillary necrosis;
• nervous system: infrequently – headache; extremely rarely - aseptic meningitis (mainly in patients with autoimmune diseases);
• cardiovascular system: with unknown frequency - peripheral edema, heart failure, increased blood pressure; with long-term use, the likelihood of thrombotic complications (myocardial infarction, stroke) increases;
• respiratory system: with unknown frequency - bronchospasm, shortness of breath, bronchial asthma;
• other reactions: extremely rarely - edema, including peripheral;
• laboratory test results: hematocrit/hemoglobin, plasma glucose concentration, CC (creatinine clearance) may decrease; plasma creatinine concentration, liver enzyme activity and bleeding time increase.

If any side effects occur, drug therapy should be stopped and consultation with a specialist should be sought.

Due to the treatment of chronic conditions and during long-term treatment, other adverse reactions may occur.

Overdose

In childhood, an overdose may occur after taking ibuprofen in a dose exceeding 400 mg/kg of the child’s weight. The dose-dependent effect of the condition in adult patients is less pronounced. T _1/2 of the substance from the body is from 1.5 to 3 hours.

Symptoms of an ibuprofen overdose are nausea/vomiting, pain in the epigastric region, and less commonly, diarrhea, headache, tinnitus, and gastrointestinal bleeding. In more severe cases, reactions from the central nervous system such as drowsiness are observed, in rare cases - convulsions, agitation, disorientation, coma. Due to severe poisoning, damage to the liver parenchyma, decreased blood pressure, cyanosis and respiratory depression, increased prothrombin time, development of metabolic acidosis, and renal failure are possible. With bronchial asthma, its exacerbation is possible.

Treatment is recommended to be symptomatic, under monitoring of airway patency, electrocardiogram data and basic vital signs of the patient, until his condition is normalized. Within an hour after taking a potentially dangerous dose of ibuprofen, it is necessary to give the patient activated charcoal or perform a gastric lavage. When ibuprofen is completely absorbed into the systemic circulation, the patient needs an alkaline drink to eliminate the acidic derivative of ibuprofen by the kidneys and forced diuresis. Frequent and/or prolonged seizures are treated with intravenous diazepam or lorazepam. Worsening of bronchial asthma requires the use of bronchodilators.

special instructions

Nurofen for children should be used for the shortest possible course, in the smallest dose effective to eliminate symptoms.

During long-term therapy, it is necessary to monitor the peripheral blood picture and the functional state of the liver and kidneys.

If symptoms of gastropathy appear, careful monitoring of the patient's condition is necessary, including esophagogastroduodenoscopy, a complete blood count (including hemoglobin determination) and a stool test for occult blood.

On the eve of the determination of 17-ketosteroids, 48 ​​hours before the study, the use of ibuprofen is stopped for a while.

Taking ethanol during drug therapy should be avoided.

Nurofen for children in the form of an oral suspension is contraindicated in patients with fructose intolerance, since it contains maltitol.

The suspension is approved for use in children with diabetes because it does not contain sugar.

Nurofen for children does not contain dyes.

In case of renal failure, before using the drug, you should consult a doctor because of the likelihood of deterioration in the functional state of the kidneys due to the use of ibuprofen.

The drug can cause fluid retention in the body, swelling and increased blood pressure, therefore, in case of arterial hypertension (including a history) and chronic heart failure, you should consult a specialist before using the drug.

Impact on the ability to drive vehicles and complex mechanisms

If adverse reactions such as drowsiness, lethargy, dizziness, blurred vision occur as a result of taking ibuprofen, you should avoid driving a vehicle or operating complex machinery during the course of therapy.

Use during pregnancy and lactation

The use of Nurofen for children during the third trimester is contraindicated. The drug should be used in the first and second trimesters or during lactation (breastfeeding) only after a doctor's permission.

There is evidence that ibuprofen can pass into breast milk in small quantities without clinically significant adverse effects on the health of the nursing baby.

Use in childhood

According to the instructions, Nurofen for children is used in childhood according to indications.

Suspensions and suppositories are contraindicated for children under 3 months of age, tablets for children under 6 years of age; The child’s weight must be more than 5 kg for suspensions, more than 6 kg for suppositories, more than 20 kg for tablets.

For impaired renal function

For liver dysfunction

The use of Nurofen is contraindicated for children with severe liver failure and active liver disease.

Use in old age

Elderly patients should prescribe the drug with caution.

Drug interactions

Medicines that should be avoided in combination with ibuprofen:

• ASA (except for low doses, not more than 75 mg/day, prescribed by a doctor): combined use may increase the likelihood of adverse reactions; ibuprofen inhibits the anti-inflammatory and antiplatelet effect of aspirin (the incidence of acute coronary insufficiency may increase in patients receiving small doses of ASA as an antiplatelet agent after starting ibuprofen);
• other NSAIDs, including selective COX-2 inhibitors: it is not recommended to use two or more drugs from the NSAID group at the same time due to a possible increase in the risk of side effects.

Ibuprofen should be used with caution concomitantly with the following medications/drugs:

• anticoagulants (including warfarin) and thrombolytics: their effectiveness may be enhanced;
• antihypertensive drugs [ACE inhibitors (angiotensin-converting enzyme) and angiotensin II receptor antagonists], diuretics: their effectiveness may decrease and a response increase in the nephrotoxicity of ibuprofen;
• GCS: increases the likelihood of ulceration of the gastrointestinal mucosa and gastrointestinal bleeding;
• cardiac glycosides: possible worsening of heart failure, decreased glomerular filtration rate and increased plasma concentration of cardiac glycosides;
• antiplatelet drugs and SSRIs (selective serotonin reuptake inhibitors): increases the risk of gastrointestinal bleeding;
• lithium preparations, methotrexate: an increase in the plasma concentration of these drugs is likely;
• mifepristone: since NSAIDs may reduce the effectiveness of mifepristone, their use should be started 8-12 days (not earlier) after using mifepristone;
• cyclosporine, tacrolimus: increases the risk of nephrotoxicity;
• zidovudine: possible increase in hematotoxicity; it is reliably known about the increased risk of hemarthrosis and hematomas in HIV-positive patients with hemophilia who received complex therapy with zidovudine and ibuprofen;
• quinolone antibiotics: increases the risk of seizures.

Analogs

Analogs of Nurofen for children are: Advil, Bonifen, Brufen SR, Deblok, Dolgit, Ibuprofen for children, Ibuprofen-Akrikhin, Ibuprofen-Hemofarm, Ibufen, Maxicold, Faspik, MIG 400, MIG, Nurofen, Nurofen forte, Nurofen Express, Nebolin, Sedalgin SPRINT, Solpaflex, Pedea, etc.

Terms and conditions of storage

Store out of reach of children at temperatures up to 25 °C. Protect tablets and suppositories from moisture.

Shelf life: tablets, suspension – 3 years, suppositories – 2 years.

Conditions for dispensing from pharmacies

Available without a prescription.

Reviews of Nurofen for children

Judging by the number of reviews, Nurofen for children is popular not only with parents and attending physicians, but also with young patients. Those who have taken the suspension note its pleasant taste. Other advantages of the drug include its high efficiency, safety and ease of use. The drug is also attractive for its low age threshold; it can be used in children from 3 months of age.

The disadvantages include the presence of contraindications, the appearance of allergic reactions with prolonged use, and it is also noted that in some children the drug does not reduce high fever immediately, but gradually.

Price for Nurofen for children in pharmacies

Approximate price of Nurofen for children, depending on the form of release and packaging: tablets of 8 pcs. per package – 97 rubles, suppositories 10 pcs. in a package - 99 rubles, suspension with orange/strawberry flavor, 150 ml in a bottle - 175 rubles.

Nurofen for children 60 mg No. 10 suppositories

Nurofen for children suppositories (candles) 60 mg 10 pcs.

Nurofen for children tablets 200 mg n8 from 6 years

Nurofen for children suppositories 60 mg n10

Nurofen for children suspension 100 mg/5 ml 100 ml strawberry

Nurofen for children suspension strawberry 100 mg/5 ml 100 ml

Nurofen for children suspension 100 mg/5 ml 150 ml strawberry

Education: First Moscow State Medical University named after I.M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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