Nazoferon composition

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NAZOFERON INSTRUCTIONS

Prices for NAZOFERON

Antimicrobial, antiviral, immunomodulatory, anti-inflammatory effects.

Nazoferon is a drug based on recombinant human interferon alpha-2b.

Table of contents:

Interferon is characterized by the ability to inhibit the replication of viruses (influenza viruses, adenoviruses, etc.) by inhibiting the processes of translation and transcription. Interferon has an antiproliferative effect, inhibiting cell reproduction. Infected with viruses (mostly RNA and DNA containing viruses). Interferon has the ability to initiate the synthesis of protein kinase, a specific enzyme that prevents translation due to phosphorylation of the initiating factor of this process. Human interferon is capable of activating a specific ribonuclease, which has a damaging effect on the messenger RNA of the viral cell. Interferon also has the following effects: stimulates the production of other cytokines, induces specific enzymes, inhibits cell proliferation, has an immunomodulatory effect by enhancing phagocytic activity and increasing the cytotoxic effect of lymphocytes towards target cells. Interferon alpha-2b has pronounced tissue specificity and is classified as an immune mediator. Interferon, thanks to its abilities, provides the body with protection against viruses, mycoplasmas, bacteria, pathogenic fungi and other pathogens of infectious diseases.

Nazoferon is prescribed for the treatment of influenza, acute respiratory viral infections, and colds in patients with frequent and long-term upper respiratory tract diseases, in children, starting from birth, in adults, including pregnant women.

Nazoferon is used for the prevention of diseases in persons who are in direct contact with patients with influenza and acute respiratory viral infections, during hypothermia, during seasonal outbreaks of disease, in groups of children and adults, as well as during epidemics among at-risk groups - teachers, medical workers, etc. d.

Nazoferon must be administered into each nasal passage in accordance with the dosage regimen. For the best distribution of the drug in the nasal cavity, it is recommended that after instillation, lightly massage the wings of the nose with your fingers for several minutes.

When the first signs of ARVI appear, incl. flu (for five days) Nazoferon is prescribed:

- children under one year old and newborns - 5 times a day, 1 drop (the daily dose of the drug is IU, a single dose is 8000 IU);

- children from one to three years old - 3 or 4 times a day, 2 doses of spray (2 drops). Daily dose: spray is IU, drops – IU, single dose: spray is –00 IU, drops –00 IU;

- children from three years to 14 years old - 4-5 times a day, 2 doses of spray (2 drops). Daily dose: spray is 000 IU, drops – 00 IU, single dose: spray – IU, drops – IU);

— adults – 5-6 times a day, 3 doses of spray (3 drops). Daily dose: spray is 0000 IU, drops – 4000 IU, single dose: spray – IU, drops – IU.

- persons who were in direct contact with patients with acute respiratory viral infections and hypothermia - twice a day according to the age dosage for 6-7 days. Preventive courses can be repeated if necessary. In the case of single contact with a patient with ARVI, one injection (instillation) of the drug is sufficient;

- during the period of seasonal increase in incidence: once in the morning according to the age-specific dosage with an interval of 1-2 days.

When using Nazoferon, no side effects of the drug were identified. However, the possibility of allergic reactions in individuals with hypersensitivity to human interferon and other components of the drug cannot be ruled out.

Nazoferon is contraindicated in persons with hypersensitivity to the components of the drug, as well as in patients with a history of severe forms of allergic diseases.

Nazoferon is safe and non-toxic, and therefore can be used during pregnancy and lactation.

When treating uncomplicated cases of ARVI, Nazoferon does not require additional symptomatic therapy (prescription of antipyretics, sulfonamides, vasoconstrictor drops, etc.). Nazoferon combines well with anti-inflammatory drugs when fever occurs. The simultaneous use of Nazoferon with intranasal vasoconstrictors is not recommended due to additional drying of the nasal mucosa.

There are no data on cases of overdose of the drug Nazoferon.

Nazoferon nasal spray, 5 ml glass bottles.

Nazoferon nasal drops, in glass bottles 5 ml.

Store at 2-8 degrees Celsius. Keep away from moisture and light. After opening the bottle, store the drug for no more than 10 days.

1 ml of Nazoferon contains:

At least IU of interferon alpha-2b.

Excipients: trometamol hydrochloride, trometamol, hypromelose, lysine hydrochloride, disodium editate, methyl parahydroxybenzoate, potassium chloride, water for injection.

Nazoferon is recommended for use by pregnant and lactating women to prevent ARVI in the early stages of pregnancy, when, due to intoxication of the maternal body, there is a high risk of developing fetal malformations.

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Source: http://www.medcentre.com.ua/medicamenty/nazoferon.html

Nazoferon

Description current as of 10/24/2014

  • Latin name: Nazoferon
  • ATX code: L03AB05
  • Active ingredient: Interferon alfa-2b (Interferon alfa-2b)
  • Manufacturer: PJSC "FARMAK", Ukraine

Compound

Nazoferon drops and spray contain the active substance: interferon alpha-2b.

Auxiliary components: trometamol hydrochloride, lysine hydrochloride, methyl parahydroxybenzoate, trometamol, hypromelose, disodium editate, potassium chloride, water for injection.

Release form

The drug is available in the form of a spray and nasal drops, placed in 5 ml glass bottles.

pharmachologic effect

Nazoferon has antimicrobial, antiviral, immunomodulatory and anti-inflammatory effects.

Pharmacodynamics and pharmacokinetics

The basis of Nazoferon is represented by a substance - recombinant human interferon alpha-2b. This component is characterized by inhibition of the replication of viruses - influenza, adenoviruses, and so on, by inhibiting the processes of transcription and translation. At the same time, interferon exhibits an antiproliferative effect due to inhibition of the reproduction of cells that are infected with viruses, mainly RNA and DNA viruses.

Also noted is the ability of interferon to initiate the synthesis of protein kinase, a specific enzyme that prevents translation due to the processes of phosphorylation of its initiating factor. In addition, human interferon activates a specific ribonuclease, which has a damaging effect on the messenger RNA of the viral cell. Additionally, the production of other cytokines is stimulated, specific enzymes are induced, cell proliferation is inhibited, and an immunomodulatory effect is manifested as a result of increased phagocytic activity and the cytotoxic effect of lymphocytes directed towards target cells. Interferon alpha-2b is characterized by pronounced tissue specificity and relationship to immune mediators. At the same time, the substance provides the human body with reliable protection against many viruses, bacteria, pathogenic fungi, mycoplasmas and other pathogens of infectious diseases.

Indications for use

The drug Nazoferon is prescribed for the treatment of:

In addition, this remedy is recommended for the purpose of therapy and prevention for pregnant women, for infants from the first days of birth, especially if they are forced to be in contact with people sick with influenza or ARVI. Also, as a prophylactic agent, the drug is used for hypothermia, during seasonal illness, and during epidemics in children's or adult groups.

Nazoferon during pregnancy

The drug is recommended for use both during breastfeeding and during pregnancy in order to prevent morbidity in the early stages, when a disease of the mother’s body can cause the development of defects in the fetus.

Contraindications for use

The drug is not prescribed for:

Side effects

Usually, treatment with Nazoferon does not cause any side effects.

However, the occurrence of allergies caused by high sensitivity or intolerance to human interferon and other components of the drug should not be excluded.

Instructions for Nazoferon (Method and dosage)

Nazoferon is intended for administration into each nasal passage, according to the established dosage regimen. In order for the product to be better distributed in the nasal cavity, after instillation, gently massage the wings of the nose with your fingers for several minutes. In pediatrics, Nazofen is actively used for children, produced in the form of drops. Instructions for children allow the use of this product even for the treatment of newborns.

Thus, the instructions for the drug recommend using Nazoferon for children when the first symptoms of ARVI or flu appear. It is advisable to do this within the first 5 days. In this case, drops for children are prescribed to newborn babies and children up to one year old, 1 drop daily. Children 1-3 years old – 2 drops 3-4 times daily.

Nazoferon spray is recommended for use in older patients, both for prevention and treatment. On average, the course can last 6-7 days. If necessary, preventive courses are repeated. Single contact with ARVI patients allows only one injection or instillation of the drug. During an increase in seasonal incidence, a single use in the morning is prescribed, according to the age-specific dosage, with an interval of 1-2 days.

Overdose

There have been no cases of Nazoferon overdose in clinical practice.

Interaction

During treatment with Nazoferon for uncomplicated cases of colds and acute respiratory viral infections, additional symptomatic therapy is not required, for example, taking antipyretic drugs, vasoconstrictors, sulfonamides, and so on. In this case, anti-inflammatory drugs may be prescribed to treat fever.

The simultaneous use of Nazoferon and intranasal vasoconstrictors helps dry out the mucous membranes of the nasal cavity.

Terms of sale

The drug is available in pharmacies without a prescription.

Storage conditions

The medicine should be stored in a dark, cool place, out of reach of children.

Best before date

2 years. After opening the bottle, if the temperature storage conditions are maintained - a temperature of 2-8 C, the medicine remains suitable for 10 days.

Analogs

The main analogue of this drug is Interferon alfa-2b.

Alcohol

There is no direct contraindication to the simultaneous use of this medicine and alcohol, but drinking alcohol with drugs containing interferon is not recommended.

Reviews about Nazoferon

As you know, this drug can be used for children almost from the moment of birth. Therefore, reviews about it are found in large numbers on various forums on the topic of children and motherhood. At the same time, many parents give a fairly high assessment of the effectiveness of Nazoferon.

The result of treatment for young children is rapid relief from mucous discharge from the nose, elimination of swelling, and so on. In addition, this children's drug is an excellent prophylactic that protects against colds and infectious diseases. You can also find reviews about Nazoferon during pregnancy, which only confirm its effectiveness.

Interferon preparations are an indispensable and highly effective means of preventing and treating infectious and colds. However, it is not recommended to use them without a doctor's prescription. In any case, in addition to the urgent use of such remedies, it is important to try to strengthen the natural immune defense, then the person will need only minimal support.

Nazoferon price, where to buy

The price of Nazoferon for children in Moscow pharmacies is rubles. The cost of the drug in the form of a spray is rubles.

Children's Nazoferon can be bought in Kyiv pharmacies for 57.38 UAH, spray - for 67.16 UAH.

  • Online pharmacies in Ukraine Ukraine

Pharmacy24

You are not the first site that writes that it can be used during pregnancy and lactation, the instructions that come in the package indicate that it is contraindicated. Explain.

Anastasia, we give the child a drop while lying down and turn the bottle upside down. So you need to drip both drops and spray. There is not a tube, but a dispenser mechanism that works upside down.

Oh, how I wanted to write a review. Yesterday I was deeply shocked when I couldn’t squeeze a single drop out of half the bottle. The point is that the tube through which the medicine enters the spray is located almost halfway up the bottle, the bottle is short and wide, so no matter where you tilt it or turn this bottle, you get zero results. I wonder what the manufacturer offers. Since it is also not possible to open a sealed bottle.

Nina V.: The article is useful, you can take note and apply it to yourself

Andrey: Not a word is said about choosing the size of stockings according to a person’s parameters: height, leg size, etc.

Olga: For coxarthrosis of the 2nd degree, I have been injecting for 4 years at the rate (after 6 months), there is no improvement.

Victoria: I don’t put my daughter in a car without taking a Dramamine tablet. We already had it.

All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://medside.ru/nazoferon

Nazoferon

Antimicrobial and antiparasitic drugs

pharmachologic effect

Antimicrobial, antiviral, immunomodulatory, anti-inflammatory effects.

Nazoferon is a drug based on recombinant human interferon alpha-2b. Interferon is characterized by the ability to inhibit the replication of viruses (influenza viruses, adenoviruses, etc.) by inhibiting the processes of translation and transcription. Interferon has an antiproliferative effect, inhibiting cell reproduction. Infected with viruses (mostly RNA and DNA containing viruses). Interferon has the ability to initiate the synthesis of protein kinase, a specific enzyme that prevents translation due to phosphorylation of the initiating factor of this process. Human interferon is capable of activating a specific ribonuclease, which has a damaging effect on the messenger RNA of the viral cell. Interferon also has the following effects: stimulates the production of other cytokines, induces specific enzymes, inhibits cell proliferation, has an immunomodulatory effect by enhancing phagocytic activity and increasing the cytotoxic effect of lymphocytes towards target cells. Interferon alpha-2b has pronounced tissue specificity and is classified as an immune mediator. Interferon, thanks to its abilities, provides the body with protection against viruses, mycoplasmas, bacteria, pathogenic fungi and other pathogens of infectious diseases.

Indications for use

Nazoferon is prescribed for the treatment of influenza, acute respiratory viral infections, and colds in patients with frequent and long-term upper respiratory tract diseases, in children, starting from birth, in adults, including pregnant women.

Nazoferon is used for the prevention of diseases in persons who are in direct contact with patients with influenza and acute respiratory viral infections, during hypothermia, during seasonal outbreaks of disease, in groups of children and adults, as well as during epidemics among at-risk groups - teachers, medical workers, etc. d.

Mode of application

Nazoferon must be administered into each nasal passage in accordance with the dosage regimen. For the best distribution of the drug in the nasal cavity, it is recommended that after instillation, lightly massage the wings of the nose with your fingers for several minutes.

When the first signs of ARVI appear, incl. flu (for five days) Nazoferon is prescribed:

children under one year old and newborns - 5 times a day, 1 drop (the daily dose of the drug is IU, a single dose is 8000 IU);

children from one to three years old - 3 or 4 times a day, 2 doses of spray (2 drops). Daily dose: spray is IU, drops – IU, single dose: spray is –00 IU, drops –00 IU;

children from three years to 14 years – 4-5 times a day, 2 doses of spray (2 drops). Daily dose: spray is 000 IU, drops – 00 IU, single dose: spray – IU, drops – IU);

adults – 5-6 times a day, 3 doses of spray (3 drops). Daily dose: spray is 0000 IU, drops – 4000 IU, single dose: spray – IU, drops – IU.

Nazoferon for the prevention of ARVI is prescribed:

for persons who were in direct contact with patients with ARVI and for hypothermia - twice a day according to the age dosage for 6-7 days. Preventive courses can be repeated if necessary. In the case of single contact with a patient with ARVI, one injection (instillation) of the drug is sufficient;

during the period of seasonal increase in incidence: once in the morning according to the age-specific dosage with an interval of 1-2 days.

Side effects

When using Nazoferon, no side effects of the drug were identified. However, the possibility of allergic reactions in individuals with hypersensitivity to human interferon and other components of the drug cannot be ruled out.

Contraindications

Nazoferon is contraindicated in persons with hypersensitivity to the components of the drug, as well as in patients with a history of severe forms of allergic diseases.

Pregnancy

Nazoferon is safe and non-toxic, and therefore can be used during pregnancy and lactation.

Interaction with other drugs

When treating uncomplicated cases of ARVI, Nazoferon does not require additional symptomatic therapy (prescription of antipyretics, sulfonamides, vasoconstrictor drops, etc.). Nazoferon combines well with anti-inflammatory drugs when fever occurs. The simultaneous use of Nazoferon with intranasal vasoconstrictors is not recommended due to additional drying of the nasal mucosa.

Overdose

There are no data on cases of overdose of the drug Nazoferon.

Release form

Nazoferon nasal spray, 5 ml glass bottles.

Nazoferon nasal drops, in glass bottles 5 ml.

Storage conditions

Store at 2-8 degrees Celsius. Keep away from moisture and light. After opening the bottle, store the drug for no more than 10 days.

Synonyms

Compound

1 ml of Nazoferon contains:

At least IU of interferon alpha-2b.

Excipients: trometamol hydrochloride, trometamol, hypromelose, lysine hydrochloride, disodium editate, methyl parahydroxybenzoate, potassium chloride, water for injection.

Nazoferon is recommended for use by pregnant and lactating women to prevent ARVI in the early stages of pregnancy, when, due to intoxication of the maternal body, there is a high risk of developing fetal malformations.

Attention

Before using Nazoferon, you should consult your doctor. This instruction is given in free translation and is intended for informational purposes only. For more complete information, please refer to the manufacturer's instructions.

Source: http://www.aptekainfo.com/pill/nazoferon/

Nazoferon, Nasal drops

Instructions for medical use

International nonproprietary name

Nasal drops IU/ml, 5ml

active substance - recombinant human interferon alpha-2 b not less than IU,

excipients: trometamol, trometamol hydrochloride, hypromelose, disodium edetate, lysine hydrochloride, potassium chloride, methyl parahydroxybenzoate, water for injection.

Transparent colorless liquid.

Immunomodulators. Immunostimulants. Interferons.

Interferon alpha-2 b.

ATX code L03A B05

NAZOFERON is an antiviral, anti-inflammatory, immunomodulatory, antiproliferative agent. The mechanism of antiviral action is to inhibit the replication of viruses (adenoviruses, influenza viruses, etc.) due to the inhibitory effect on the processes of transcription and translation; antiproliferative – inhibits cell reproduction (most DNA and RNA viruses). Interferon initiates the synthesis of a specific enzyme - protein kinase, which prevents translation due to phosphorylation of one of the initiating factors of this process; activates a specific ribonuclease, which damages the messenger RNA of the virus. The effects of interferon also include: stimulation of the production of other cytokines, induction of specific enzymes, inhibition of cell proliferation, immunomodulation (increased phagocytic activity of macrophages and specific cytotoxicity of lymphocytes towards target cells). Interferon is a mediator of immunity and has pronounced tissue specificity. Thanks to its effects, interferon protects the body from pathogens of infectious diseases (viruses, bacteria, mycoplasmas, pathogenic fungi, etc.).

Indications for use

Prevention and treatment of ARVI, colds:

  • in children from 1 month and adults;
  • in patients who often and for a long time suffer from diseases of the upper respiratory tract;
  • upon contact with ARVI patients;
  • with a seasonal increase in morbidity in organized groups (children and adults), among “at-risk” contingents - medical workers, teachers, etc., especially during an epidemic.

Directions for use and doses

At the first sign of ARVI (within 5 days)

Children from 1 month to 1 year – 1 drop in each nasal passage 5 times a day (single dose – 8000 IU, daily dose – IU);

Children from 1 to 3 years old – 2 drops 3-4 times a day (single dose – IU, daily dose – 00 IU);

Children from 3 to 14 years old – 2 drops 4-5 times a day (single dose – IU, daily dose – 00 IU);

Adults – 3 drops 5-6 times a day (single dose – IU, daily dose – 4000 IU).

For the prevention of respiratory viral infections

In case of contact with a patient and in case of hypothermia - in accordance with the age-specific dosage, 2 times a day for 5-7 days. If necessary, preventive courses are repeated. For single contact, one instillation is sufficient.

In case of seasonal increase in incidence - in accordance with the age dosage, once in the morning with an interval of 1-2 days.

  • skin rash
  • dry nasal mucosa

Contraindications

  • hypersensitivity to interferon alpha-2b and other components included in the drug
  • history of severe forms of allergic diseases.

When using the drug NAZOFERON in uncomplicated cases, no additional symptomatic treatment is required (paracetamol, sulfonamides, vasoconstrictor nasal drops). At elevated body temperatures, the drug is combined with anti-inflammatory drugs. The simultaneous use of intranasal vasoconstrictor drugs is not recommended, as they dry out the nasal mucosa.

Inject into each nasal passage according to the method of application and dosage. After instillation, it is recommended to massage the wings of the nose with your fingers for several minutes to evenly distribute the drug in the nasal cavity.

Scheme for using nasal drops in a bottle sealed with a dropper:

The drug should not be used if the integrity and labeling of the packaging is damaged, if the physical properties (color or transparency of the liquid) change, or after the expiration date.

Use in pediatrics

The drug is used for children from 1 month.

Use during pregnancy and lactation

There is no data on the use of NAZOFERON in pregnant and breastfeeding women.

Features of the effect of the drug on the ability to drive vehicles and potentially dangerous mechanisms

Release form and packaging

5 ml of the drug is poured into bottles made of brown glass of the 1st hydrolytic class, sealed with rubber stoppers for injection bottles and aluminum caps combined with plastic caps or caps with a hinged cap.

Self-adhesive labels are placed on the bottles.

One bottle, along with a transparent polypropylene pipette and a protective cap for pipettes, previously placed in a plastic film bag, and instructions for medical use in the state and Russian languages ​​are placed in a cardboard box.

Or 5 ml of the drug is poured into brown glass vials for injection, sealed with droppers.

Self-adhesive labels are placed on the bottles.

One bottle, along with instructions for medical use in the state and Russian languages, is placed in a cardboard box.

Store in a place protected from light at a temperature of 2 to 8 °C.

Keep out of the reach of children!

Shelf life after opening the bottle is 10 days.

Do not use the drug after the expiration date indicated on the package.

Conditions for dispensing from pharmacies

PJSC "Farmak", Ukraine, 04080, Kyiv, st. Frunze, 63.

Registration Certificate Holder

Address of the organization that accepts claims from consumers regarding the quality of products (products) on the territory of the Republic of Kazakhstan

Republic of Kazakhstan, Almaty, st. Abaya 157, office 5

Tel/fax: , email:

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Nazoferon

Instructions for use:

Nazoferon is a drug with immunomodulatory, antimicrobial, antiviral and anti-inflammatory effects.

Release form and composition

Nazoferon is available in two dosage forms:

  • Nasal drops: colorless, transparent (5 ml in glass bottles sealed with droppers, 1 bottle in a cardboard box);
  • Nasal spray: colorless, transparent (5 ml in glass bottles closed with a dispenser pump, 1 bottle in a cardboard box complete with a nasal spray).

The composition of 1 ml of nasal drops and spray includes:

  • Active ingredient: alpha-2b recombinant human interferon - not less than IU (international units);
  • Auxiliary components: lysine hydrochloride, potassium chloride, disodium edetate, trometamol hydrochloride, trometamol, hypromellose, methyl parahydroxybenzoate, water for injection.

Indications for use

Nazoferon is prescribed for the treatment and prevention of acute respiratory viral infections and colds in patients of all ages. The drug is used for long-term and frequent diseases of the upper respiratory tract, as well as in the following situations:

  • Contact with patients with acute respiratory viral infections;
  • Hypothermia;
  • Seasonal increase in morbidity in organized groups, adults and children, especially during periods of epidemics (in the high-risk group - medical workers, teachers, kindergarten teachers, etc.).

Contraindications

  • Age up to 1 year (nasal spray);
  • Severe forms of allergic diseases (history);
  • Hypersensitivity to the components of the drug.

Directions for use and dosage

Treatment of acute respiratory viral infections should begin when the first signs of the disease develop (within 5 days).

The following dosage regimen is usually prescribed (frequency of use/single dose (number of drops or spray doses in each nasal passage)/daily dose):

  • Newborns and children under 1 year: drops – 5 times a day/8000 IU (1 drop)/IU;
  • Children 1-3 years old: drops – 3-4 times a day/IU (2 drops)/000 IU; spray – 3-4 times a day/IU (2 spray doses)/000 IU;
  • Children 3-14 years old: drops – 4-5 times a day/IU (2 drops)/000 IU; spray – 4-5 times a day/IU (2 spray doses)/000 IU;
  • Adults: drops – 5-6 times a day/IU (3 drops)/0 IU; spray – 5-6 times a day/IU (3 spray doses)/0 IU.

In case of contact with patients and hypothermia, Nazoferon is prescribed for prophylactic purposes 2 times a day in accordance with the age-specific dosage, course duration is 5-7 days. If necessary, preventive courses can be repeated. For single contact with patients, one spray or instillation is usually sufficient.

For prophylaxis during seasonal increases in incidence, Nazoferon is used once in the morning in accordance with the age-specific dosage with an interval of 1-2 days.

Side effects

In isolated cases, when using Nazoferon, a skin rash may occur.

special instructions

Before using Nazoferon in the form of nasal drops, you need to take a sitting or lying position on your back. When instilling, do not touch the inner walls of the nose with the dropper of the bottle. To evenly distribute the drops over the nasal mucosa, immediately after the procedure, you need to massage the wings of the nose with your fingers for several minutes.

The nasal spray should be used while in an upright position. Before first use, you must activate the sprayer by pressing.

If the labeling and integrity of the packaging are violated, as well as in cases of changes in the physical properties of Nazoferon (transparency or color), the drug should not be used in any dosage form.

To avoid the spread of infection, individual use of the drug is recommended.

Drug interactions

When using Nazoferon in uncomplicated cases, additional symptomatic therapy (for example, paracetamol, sulfonamides, vasoconstrictor nasal drops) is not required.

The simultaneous use of Nazoferon with intranasal vasoconstrictor drugs is not recommended, since they can lead to dryness of the nasal mucosa.

At elevated body temperatures, combination treatment with anti-inflammatory drugs is possible.

Analogs

Analogs of Nazoferon are: Interferon alfa-2b, Arbidol, Amiksin, Viferon.

Terms and conditions of storage

Store in a place protected from light, out of reach of children, at a temperature of 2-8°C.

Shelf life – 2 years.

Drops or spray after opening the bottle can be used for 10 days, provided the drug is stored at a temperature of 2-8°C (in the refrigerator).

Conditions for dispensing from pharmacies

Available without a prescription.

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Source: http://www.neboleem.net/nazoferon.php

Nazoferon - instructions for use and analogues of the drug Nazoferon

Latin name: Nazoferon

Active ingredient: Interferon

Manufacturer: Farmak, Ukraine

Condition for dispensing from the pharmacy: Without a prescription

“Nazoferon” exhibits antimicrobial, antiviral, anti-inflammatory and immunomodulatory effects. It is actively used to relieve symptoms of nasal congestion and is an active obstacle to the penetration of viral cells into the body.

Indications for use

“Nazoferon” is used for the following purposes:

  1. Active therapy of colds, relief of symptoms of influenza and ARVI:
    • In children of any age and other persons, not excluding pregnant women at all stages
    • In persons suffering from respiratory tract diseases, including cases of chronic course
    • In persons in contact with infected viral diseases
    • With prolonged cooling of the body.
  2. Preventive measures in epidemically dangerous seasons, when contacts with carriers of viral diseases occur, when organizing anti-epidemic measures in schools, kindergartens, and dense work groups.

Compound

The main part of the drug “Nazoferon” is IU/ml interferon alpha-2b.

Additional components are:

  • Trometamol hydrochloride
  • Hypromelose
  • Dinathium editate (Trilon B)
  • Lysine hydrochloride
  • Potassium chloride
  • Methyl parahydroxybenzoate
  • Injection water

Medicinal properties

“Nazoferon” is a medicinal product containing recombinant human interferon alpha-2b in its base. This basis negatively affects the reproduction of viral cells (for example, influenza or adenovirus) by suppressing the processes of information transfer from infected cells to healthy ones.

This inhibition prevents viral cells from freely moving distorted information in sections of DNA and RNA, which greatly inhibits their development and allows the body’s natural defenses to actively destroy foreign objects.

The synthesis of protein kinase due to the action of interferon increases significantly, increasing the natural protective reaction of the human body. In addition, specific RNA is also activated under the influence of alpha-2b and destroys sections of viral RNA.

Other positive effects of human interferon on processes in the body:

  1. Increases the formation of cellular products that protect the information part of the cell
  2. Increases the formation of specific protective enzymes
  3. It enhances the effect of phagocytes and the cytotoxic effect of lymphocytes on affected cells, thereby exerting its effect on the body as a whole as an immunomodulator.

Thanks to interferon alpha-2b, “Nazoferon” actively affects the viability of viruses, mycoplasmas, bacteria and other causes of infectious diseases.

Average price from 400 to 420 rubles.

“Nazoferon”, spray

Nasal spray ME/ml, glass bottle 5 ml. The spray is actively used to relieve symptoms in patients aged one year or more, due to its convenient dosing mechanism and form, in which the active substance is sprayed evenly over the entire surface of the mucosa.

Mode of application

Method of administration: insert the tip of the spray bottle into the nasal cavity cleared of mucus, press the injection mechanism the appropriate number of times.

Instructions for using the drug “Nazoferon” to relieve symptoms of viral diseases:

  • Children under 1 year – 1 drop up to 5 times a day
  • Children from 1 to 3 years – 2 drops (spray doses) up to 4 times a day
  • Children from 3 to 14 years old – 2 drops (spray doses) up to 5 times a day
  • Children over 14 years of age and adults – 3 drops (spray doses) up to 6 times a day.

During the anti-epidemic regime:

  • In a work group, kindergarten, school - a single dose in the morning, according to age, every other day throughout the entire period of the epidemic
  • When in contact with an infected person - twice a day for a week, according to the age category.

Average price from 370 to 390 rubles.

“Nazoferon”, drops

Nasal drops IU/ml, glass bottle 5 ml. Drops are used more often to treat adults and children under 1 year of age, since this dosage form penetrates to the desired areas in a dosed manner, but without sudden pressure. The average price is 370 – 390 rubles.

Mode of application

Dosages are similar to the spray. It is best to administer nasal drops while lying down, or tilt your head back strongly - the pipette is inserted into the cleansed nasal passage and the prescribed number of drops is dripped. After administering the medicine, it is recommended to make light massaging movements on the wings of the nose to evenly distribute the medicine.

Contraindications

There are two main types of contraindications to this drug:

  • Individual hypersensitivity (intolerance) to the components of the drug
  • A history of severe allergies, regardless of the type of allergen.

During pregnancy and breastfeeding

The use of “Nazoferon” in pregnant and lactating women is similar to the dosage regimen in their age category. The absolute safety of the drug for these categories of people has been clinically proven.

Precautionary measures

It is recommended to use Nazoferon with caution for the first time. It is best to apply a small amount of the drug to the sensitive skin of the elbow. If no reaction is observed on the skin within 20 minutes. You can use the medicine as directed. In case of redness, itching or other discomfort, it is better to refuse use.

Cross-drug interactions

Interacts well with various anti-inflammatory drugs and antipyretics.

It is not recommended to use in combination with vasoconstrictors due to the high risk of damage to the mucous membrane.

Side effects

Due to the low toxicity of the drug, no side effects were identified.

Overdose

In clinical practice, there is no data on cases of drug overdose.

Conditions and shelf life

To store the drug “Nazoferon” use a dry, dark place, temperature range from 2 to 8 degrees.

A sealed bottle can be stored for two years from the date of manufacture. Opened product is recommended to be used within 10 days.

Analogs

"Interferon"

Microgen, Russia / Schering-Plough, USA, etc.

The release form of interferon includes many types - ointments, gels, suppositories, drops, ampoules and others. The action is aimed at actively increasing immunity and the body’s overall resistance to viral attacks.

  • Short shelf life
  • Inconvenient storage and use (applies to suppositories and ampoules)

“Grippferon”

The solution is pale yellow in color, packaged in plastic bottles of 5 and 10 ml. Has antiviral and anti-inflammatory properties.

  • Good drug tolerance
  • Possibility of use during pregnancy and feeding
  • Short shelf life of opened packaging
  • Fast consumption.

Source: http://lekhar.ru/lekarstva/immunitet/nazoferon-instrukciya-po-primeneniyu/

Nazoferon composition

INDICATIONS FOR USE:

in patients who often and for a long time suffer from diseases of the upper respiratory tract;

upon contact with patients with ARVI and influenza;

children from 1 to 3 years old - 2 drops (spray doses) 3-4 times a day (single dose: drops - IU, spray - IU, daily dose: drops - 00 IU, spray - 00 IU);

children from 3 to 14 years old - 2 drops (spray doses) 4-5 times a day (single dose: drops - IU, spray - IU, daily dose: drops - 00 IU, spray - 000 IU);

adults - 3 drops (spray doses) 5-6 times a day (single dose: drops - IU, spray - IU, daily dose: drops - 4000 IU, spray - 0000 IU).

Source: http://www.medsite.com.ua/lekartvennii_preparat_farmak-nazoferon_561.html

Nazoferon

Instructions for use:

Latin name: Nazoferon

ATX code: L03AB05

Active ingredient: Interferon alfa-2b (Interferon alfa-2b)

Analogues: Interferon alpha-2b, Arbidol, Amiksin, Viferon

Manufacturer: PJSC "FARMAK", Ukraine

Description valid as of: 10/02/17

Nazoferon is an antiviral and immunomodulatory drug. It has a pronounced antiviral, anti-inflammatory, immunomodulatory and antimicrobial effect on the body. This drug is intended for the treatment and prevention of viral diseases. The active substance of Nazoferon is interferon alpha-2b.

Active substance

Interferon alfa-2b.

Release form and composition

The drug is produced by the manufacturer in 5 ml bottles in two dosage forms - in the form of nasal drops and Nazoferon nasal spray. 1 ml of solution contains at least IU of interferon alpha-2b.

Children's Nazoferon is considered to be a drug in the form of drops, since its bottle is equipped with a convenient, most accurate dosing device.

Indications for use

Nazoferon is used in the following cases:
  • for the treatment of influenza and ARVI in patients of all age groups, including pregnant women and newborns;
  • for frequent and long-term diseases of the upper respiratory tract;
  • as a prophylactic agent that protects against viral infections during contact with patients with influenza, hypothermia, and also during epidemics.

Nazoferon is prescribed to pregnant and lactating women as an effective and at the same time safe medicine to prevent the development of viral diseases.

Contraindications

The drug should not be used if you are hypersensitive to its components. Drops and spray are also contraindicated in severe forms of allergic diseases.

Instructions for use Nazoferon (method and dosage)

Nazoferon spray or drops are administered into each nasal passage. To distribute the solution evenly after administering the drug, it is recommended to lightly massage the wings of the nose with your fingers. Nazoferon should be used within 5 days after the first signs of influenza or ARVI appear.

The dosage form of the drug and its dosage depend on the age of the patient. Babies under one year of age are prescribed Nazoferon drops (1 drop no more than 5 times a day at the maximum daily dose of ME). To treat children aged 1-3 years, you can use not only drops, but also a spray. The treatment regimen in this case looks like this: 2 doses of spray or 2 drops of baby product 3-4 times a day. For children aged 3-14 years, the drug is prescribed 2 drops 4-5 times a day.

Adult patients are recommended to administer 3 drops of the drug or 3 doses of Nazoferon spray into each nasal passage up to 6 times a day.

If the medicine is used as a prophylactic against hypothermia or prolonged contact with patients with influenza, the drug is taken for 5-7 days in a dosage appropriate to the patient’s age. If contact with the patient was short-lived, Nazoferon is used once.

During seasonal epidemics of viral diseases, the drug should be taken in the morning in accordance with the recommended dosage (daily or every 2 days).

Side effects

Nazoferon is well tolerated by patients of all age groups, and side effects are usually not observed when treated with it.

Overdose

There have been no cases of overdose with the nasal spray or the children's drug.

Analogs

Interferon alpha-2b, Arbidol, Amiksin, Viferon.

pharmachologic effect

The drug has a pronounced immunomodulatory, antiviral, antimicrobial and anti-inflammatory effect, which is due to the properties of its active component - human interferon alpha-2b. Once in the human body, interferon activates the synthesis of enzymes that inhibit the development of viruses and the reproduction of infected cells.

The drug provides reliable protection of the body from pathogens of infectious diseases (including bacteria, viruses, mycoplasma and pathogenic fungi).

special instructions

There is no direct contraindication to the simultaneous use of this medicine and alcohol, but drinking alcohol with drugs containing interferon is not recommended.

During pregnancy and breastfeeding

Can be used during pregnancy and breastfeeding.

In childhood

Drops can be used in children from birth, following the recommended dosage. From 1 year of age you can also use Nazoferon spray.

In old age

Drug interactions

Drops or spray can be combined with other cold medicines. Simultaneous intranasal administration of Nazoferon and vasoconstrictor drugs is not recommended, since such a combination can lead to excessive dryness of the nasal mucosa.

Conditions for dispensing from pharmacies

Available without a prescription.

Storage conditions and periods

Nazoferon should be stored in a dry place, protected from light, at an air temperature of 2 to 8 ° C. The shelf life of the solution in a closed bottle is 2 years, and in an open bottle no more than 10 days.

Price in pharmacies

Nazoferon price for 1 package from 380 rubles.

The description posted on this page is a simplified version of the official version of the annotation for the drug. The information is provided for informational purposes only and does not constitute a guide for self-medication. Before using the medicine, you must consult a specialist and read the instructions approved by the manufacturer.

When using materials from the site, the active reference is obligatory.

The information presented on our website should not be used for self-diagnosis and treatment and cannot serve as a substitute for consultation with a doctor. We warn you about the presence of contraindications. Specialist consultation is required.

Source: http://dolgojit.net/nazoferon.php