Sodium thiochloride

Posted on by admin

Sodium chloride - characteristics, properties, instructions for use, side effects, interactions with other drugs

Compound

1. Isotonic (physiological) 0.9% solution containing sodium chloride – 9 g, distilled water – up to 1 liter.

Table of contents:

2. Hypertonic 10% solution containing sodium chloride - 100 g, distilled water - up to 1 liter.

Release form

  • To dissolve medicinal substances for intramuscular and subcutaneous injections, a 0.9% sodium chloride solution is produced in ampoules of 5, 10, 20 ml.
  • For dissolving medications, intravenous drips, enemas and external use: 0.9% sodium chloride solution in bottles of 100, 200, 400 and 1000 ml.
  • For intravenous injection and external use: 10% sodium chloride solution in bottles of 200 and 400 ml.
  • For oral (inside) administration: tablets 0.9 g. To use, the tablet must be dissolved in 100 ml of boiled warm water.
  • For treating the nasal cavity: nasal spray – 10 ml.

pharmachologic effect

Indications for use

  • Restoring water balance in case of body dehydration caused by various reasons.
  • Maintaining plasma volume during surgery and after.
  • Detoxification of the body (food poisoning, dysentery, cholera, etc.).
  • Maintaining plasma volume in case of extensive burns, diarrhea, blood loss, diabetic coma.
  • Eye rinsing for inflammatory and allergic irritations of the cornea.
  • Rinsing the nasal mucosa for allergic rhinitis, nasopharyngitis, prevention of sinusitis, acute respiratory infections, after removal of polyps and adenoids.
  • Inhalation of the respiratory tract (using special devices - inhalers).

It is used to treat wounds, moisturize bandages and fabric dressings. The neutral environment of saline is well suited for dissolving drugs and co-infusion with other drugs.

1. Deficiency of the elements sodium and chlorine.

2. Dehydration due to various reasons: pulmonary, gastric and intestinal bleeding, burns, vomiting, diarrhea.

Sodium chloride - instructions for use

With long-term use of large doses of sodium chloride, it is necessary to analyze the content of electrolytes in plasma and urine.

Sodium chloride 10 - instructions for use

Sodium chloride 9 - instructions for use

Contraindications

  • increased content of sodium ions in the body;
  • increased content of chlorine ions in the body;
  • lack of potassium;
  • circulatory fluid disorders, with the possibility of cerebral and pulmonary edema;
  • cerebral edema, pulmonary edema;
  • acute heart failure;
  • intracellular dehydration;
  • extracellular excess fluid;
  • treatment with significant doses of corticosteroids.

Used with great caution in patients with changes in renal excretory function, as well as in children and the elderly.

Side effects

  • discomfort in the digestive system: nausea, vomiting, stomach cramps, diarrhea;
  • disorders of the nervous system: lacrimation, constant thirst, anxiety, sweating, dizziness, headache, weakness;
  • arterial hypertension, rapid heartbeat and pulse;
  • dermatitis;
  • menstrual irregularities;
  • anemia;
  • excess fluid content in the body or its parts (edema), which indicates a pathological shift in water-salt metabolism;
  • acidosis – a shift in the body’s acid-base balance towards increased acidity;
  • hypokalemia – a decrease in potassium content in the body’s blood.

If side effects occur, the drug should be stopped. It is necessary to assess the patient’s well-being, provide adequate assistance and save the bottle with the remaining solution for analysis.

Sodium chloride during pregnancy

1. Preeclampsia (increased concentration of sodium in the blood plasma) with severe swelling.

2. Moderate and severe stages of toxicosis.

Interaction with other drugs

Synonymous drugs for sodium chloride

  • Sodium chloride 0.9% for intravenous infusion - sterile solution in bottles.
  • Sodium chloride 1.6% for intravenous infusion.
  • Sodium chloride 12% for intravenous infusion.
  • Sodium chloride Brown (Germany) - powder for the preparation of solution for injection, solution for infusion, solution for injection, solvent for the preparation of dosage forms for injection, nasal spray.
  • Sodium chloride bufus – powder for the preparation of solution for injection, solution for infusion, solution for injection, solvent for the preparation of dosage forms for injection, nasal spray.
  • Sodium chloride-Cinco – isotonic solution for infusion, hypertonic solution, eye drops and eye ointment.
  • Sodium chloride – 0.9% solution for infusion (Bulgaria).
  • Salorid – 0.9% solution for infusion (Bangladesh).
  • Rizosin – 0.65% nasal spray with and without menthol.
  • Salin – 0.65% nasal spray (India).
  • No-salt – 0.65% nasal spray.
  • Physiodose – 0.9% solution for topical use.

Additional Information

1. Remove container from outer packaging immediately before use. It protects and maintains the sterility of the drug.

2. Squeeze the container tightly and check for integrity. If damage is found, discard the container, as the solution in it is dangerous.

3. Check the solution visually: for transparency, absence of impurities and inclusions. If present, discard the container.

4. Hang the container on a tripod, remove the plastic fuse and unscrew the lid.

5. Add medications into the solution following aseptic rules. Move the clamp that regulates the movement of the solution to the “closed” position. Disinfect the area of ​​the injection container, make a puncture in it with a syringe and inject the drug. Mix well. Move the clamp to the “open” position.

Storage conditions and expiration dates

  • powder and tablets - without restrictions;
  • 0.9% solution in ampoules – 5 years;
  • 0.9% solution in bottles – 12 months;
  • 10% solution in bottles – 2 years.

Do not use after expiration date. Before using any drug containing sodium chloride, you should consult your doctor.

Read more:
Leave feedback

You can add your comments and feedback to this article, subject to the Discussion Rules.

Source: http://www.tiensmed.ru/news/natriahlorid-ec7.html

Sodium chloride

Instructions for use:

Prices in online pharmacies:

Sodium chloride is a plasma substituting agent.

pharmachologic effect

The product has a rehydrating (restoring water balance) and detoxifying effect. Thanks to replenishing sodium deficiency, it is effective in various pathological conditions.

Sodium chloride 0.9% has the same osmotic pressure as that of human blood, therefore it is able to be rapidly excreted, only briefly increasing the volume of circulating blood.

External use of sodium chloride saline solution helps remove pus from the wound and eliminate pathological microflora.

Intravenous infusion of sodium chloride solution increases urine output and replenishes the lack of chlorine and sodium.

Release form

Sodium chloride is produced in the form of a powder, solution, solvent for some medications, and nasal spray.

Indications for use Sodium chloride

Sodium chloride 0.9% is prescribed for large losses of extracellular fluid or in conditions in which its supply is limited - cholera, dyspepsia caused by poisoning, diarrhea, vomiting, large burns. The solution is effective for hyponatremia, hypochloremia, accompanied by dehydration.

Externally, saline solution of sodium chloride is used to wash the eyes, nose, wounds, and to moisten dressings.

The solution is also used for stomach, intestinal, and pulmonary bleeding, for poisoning, constipation, and for forced diuresis.

Contraindications

You should not take sodium chloride with: high sodium levels, with hypokalemia, extracellular hyperhydration, blood circulation disorders, due to which pulmonary or cerebral edema may develop, with acute left ventricular failure, renal failure, decompensated chronic heart failure.

It is not recommended to combine the drug with high doses of glucocorticosteroids.

When prescribing sodium chloride solution in large dosages, it is necessary to monitor the level of electrolytes in urine and plasma.

Do not inject the solution under the skin - tissue necrosis may develop.

Instructions for use Sodium chloride

Before administration, the sodium chloride solution should be heated to 36-38 degrees. In case of dehydration, the dosage of the product is determined individually and averages 1 l/day. If the poisoning is severe or there is a large loss of fluid, you can administer the solution in an amount of up to 3 liters per day. In this case, a sodium chloride dropper is used, the drug is administered at a speed of 540 ml/hour.

For children with dehydration accompanied by low blood pressure, the solution is started to be administered in an amount of 20-30 ml/kg of weight.

To lavage the stomach, use a 2-5% solution; to eliminate constipation, use enemas with a 5% solution - 75-00 ml is administered rectally.

A dropper of sodium chloride 10% is used for intestinal, gastric, and pulmonary bleeding; to enhance diuresis, 10-20 ml of solution is slowly injected intravenously.

When carrying out complex treatment of respiratory tract diseases, rinses, rubdowns and baths with a 1-2% solution are prescribed.

For the treatment of colds, sodium chloride for inhalation is used as an adjuvant. For children, the drug Lazolvan is mixed with a solution - 1 ml of each product and inhaled three times a day for 5-7 minutes. Adults can inhale for 10 minutes.

Sodium chloride for inhalation can also be combined with Berodual, a bronchodilator. To carry out the procedure, mix 2-4 ml of Berodual and 1-1.5 ml of sodium chloride 0.9%.

Side effects

Long-term use of the solution and its use in excessive dosages can provoke overhydration, acidosis, and hypokalemia.

Sodium chloride solvent 0.9% 5 ml 10 pcs.

Sodium chloride solution 0.9% 200 ml

Sodium chloride solution 0.9% 250 ml

Sodium chloride injection solution 0.9% 5 ml n10 amp

Sodium chloride solvent 0.9% 10 ml 10 pcs.

Sodium chloride solution 0.9% 100 ml

Sodium chloride solution 0.9% 200 ml

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

The cough medicine “Terpinkod” is one of the top sellers, not at all because of its medicinal properties.

The average life expectancy of left-handers is shorter than that of right-handers.

More than $500 million a year is spent on allergy medications in the United States alone. Do you still believe that a way to finally defeat allergies will be found?

Scientists from Oxford University conducted a series of studies in which they came to the conclusion that vegetarianism can be harmful to the human brain, as it leads to a decrease in its mass. Therefore, scientists recommend not completely excluding fish and meat from your diet.

Dentists appeared relatively recently. Back in the 19th century, pulling out diseased teeth was the responsibility of an ordinary hairdresser.

Regular use of a solarium increases your chance of developing skin cancer by 60%.

Research shows that women who drink several glasses of beer or wine per week have an increased risk of developing breast cancer.

During operation, our brain expends an amount of energy equal to a 10-watt light bulb. So the image of a light bulb above your head at the moment an interesting thought arises is not so far from the truth.

An educated person is less susceptible to brain diseases. Intellectual activity promotes the formation of additional tissue that compensates for the disease.

In an effort to get the patient out, doctors often go too far. For example, a certain Charles Jensen in the period from 1954 to 1994. survived more than 900 operations to remove tumors.

The human brain weighs about 2% of the total body weight, but it consumes about 20% of the oxygen entering the blood. This fact makes the human brain extremely susceptible to damage caused by a lack of oxygen.

Our kidneys are capable of purifying three liters of blood in one minute.

The well-known drug Viagra was originally developed for the treatment of arterial hypertension.

When lovers kiss, each of them loses 6.4 calories per minute, but at the same time they exchange almost 300 types of different bacteria.

According to statistics, on Mondays the risk of back injuries increases by 25%, and the risk of a heart attack by 33%. Be careful.

The German healthcare system is considered one of the best in Europe and throughout the world. Oncologists in Germany have achieved particular success. After therapy in clinics of the countries.

Source: http://www.neboleem.net/natrija-chlorid.php

SODIUM CHLORIDE

250 ml - polymer containers (32) - transport containers.

500 ml - polymer containers (20) - transport containers.

1000 ml - polymer containers (10) - transport containers.

Has a detoxifying and rehydrating effect. Replenishes sodium deficiency in various pathological conditions of the body. A 0.9% solution of sodium chloride is isotonic to human plasma, therefore it is quickly removed from the vascular bed and only temporarily increases the volume of blood volume.

Concentration of sodium immol/l (plasma) and 145 mmol/l (interstitial fluid), chloride concentration 101 mmol/l (interstitial fluid). Excreted by the kidneys.

- plasma isotonic fluid replacement;

— dissolution and dilution of drugs.

- circulatory disorders that threaten cerebral and pulmonary edema;

- cerebral edema;

- concomitant therapy with corticosteroids in large doses.

With caution: chronic heart failure, chronic renal failure, acidosis, arterial hypertension, peripheral edema, toxicosis of pregnancy.

IV. Before administration, the drug should be warmed to 36-38°C. The average dose is 1000 ml/day as an intravenous, continuous drip infusion with an administration rate of up to 180 drops/min. In case of large fluid losses and intoxications (toxic dyspepsia, cholera), it is possible to administer up to 3000 ml/day.

Children with shock dehydration (without determining laboratory parameters) are administered ml/kg. The dosage regimen is adjusted depending on laboratory parameters (electrolytes Na +, K +, Cl -, acid-base state of the blood).

Acidosis, overhydration, hypokalemia.

Symptoms: administration of large volumes of 0.9% sodium chloride to patients with impaired renal excretory function can lead to chloride acidosis, overhydration, and increased excretion of potassium from the body.

Treatment: in case of overdose, the drug should be discontinued and symptomatic therapy performed.

Compatible with colloid hemodynamic blood substitutes (mutually enhancing effect). When adding other drugs to the solution, it is necessary to visually monitor compatibility.

Influence on the ability to drive vehicles and operate machinery.

Does not affect the ability to drive vehicles.

Can be used during pregnancy and lactation.

Store the drug at a temperature not exceeding 25°C. Freezing the drug, provided the packaging remains sealed, is not a contraindication to its use. After transportation at subzero temperatures, containers in transport containers must be kept at a temperature of 15° to 25°C until completely defrosted. If the contents of the container become cloudy, do not use. Keep out of the reach of children.

Shelf life: 2 years. Do not use after expiration date.

To ask a question about the project or contact the editors, use this form.

Source: http://health.mail.ru/drug/natriya_chlorid/

Sodium chloride

Prices in online pharmacies:

Sodium chloride is a plasma replacement drug.

Pharmacological action of Sodium chloride

The drug is aimed at restoring water balance and has a detoxifying effect. Due to the fact that the drug replenishes sodium deficiency, it is effective in various pathological conditions.

Sodium chloride 0.9% has the same osmotic pressure as human blood. For this reason, the drug is quickly eliminated from the body and increases the volume of circulating blood for a short period of time.

When applied externally, saline solution of sodium chloride can remove pus from the wound or restore the microflora.

If an intravenous infusion of sodium chloride solution is performed, the patient will increase urination and also replenish the lack of sodium and chlorine.

Release form

The drug is available in the form of a powder, a solvent for certain medications, a solution or a nasal spray.

Indications for use

Experts recommend prescribing sodium chloride 0.9% for large losses of extracellular fluid or in cases where its supply decreases. This can be dyspepsia (which is caused by poisoning), cholera, diarrhea, vomiting, and also large burns. This solution is effective for hyponatremia and hypochloremia, which is accompanied by dehydration.

Externally, sodium chloride saline solution should be used to wash the nose, wounds, and to moisten bandages.

In addition, the solution is used for bleeding of various types (gastric, intestinal, pulmonary), for poisoning, constipation, or for forced diuresis.

Contraindications

Experts do not recommend using the drug for: extracellular hyperhydration, blood circulation disorders (pulmonary or cerebral edema may develop), high sodium levels, acute left ventricular failure, hypokalemia, renal failure and decompensated cardiac failure.

The drug Sodium chloride should not be mixed with large doses of glucocorticosteroids. If the solution is prescribed in large dosages, the level of electrolytes in the urine or plasma should be monitored.

Directions for use and dosage

Before administration begins, the sodium chloride solution must be heated to 100 degrees. In case of dehydration, the dosage is determined individually. The average dose is 1 liter per day.

If the patient is severely poisoned or there is a large loss of fluid, it is recommended to administer the solution up to 3 liters per day. In this case, a sodium chloride dropper is used. The product should be administered at a speed of 540 milliliters per hour.

Children who are found to be dehydrated, accompanied by a decrease in blood pressure, must be administered a solution in the amount of milliliters per 1 kilogram of weight.

To perform gastric lavage, use a 2-5 percent solution; to eliminate constipation, use enemas with a 5 percent solution (administer 75 milliliters rectally).

A dropper of sodium chloride 10 percent is prescribed for pulmonary bleeding, intestinal bleeding, and to increase diuresis. In these situations, the drug must be administered slowly (10-20 milliliters of solution).

In the case of complex therapy for diseases of the upper respiratory tract, experts recommend rinsing, rubbing and bathing (1-2 percent solution).

When treating colds, sodium chloride is used for inhalation (used as an adjuvant). Adults are allowed to inhale for 10 minutes, and children - 3 times a day for 5-7 minutes (in this case, the solution is mixed with Lazolvan in a ratio of 1 to 1 ml).

For inhalation it is also allowed to be combined with Berodual.

special instructions

Large volumes of the drug should be used with caution in patients who have impaired renal excretory function.

You can freeze the medicine as long as the container remains sealed. If the solution is mixed with other drugs, it is recommended to visually check the compatibility (invisible as well as therapeutic incompatibility is possible).

It is recommended to store the plasma replacement agent at a temperature not exceeding 25 degrees Celsius. Avoid getting sodium chloride solution into children's hands. After the expiration date, do not use the medicine.

In case of prolonged use of the solution, as well as its use in increased dosages, hypokalemia and acidosis may occur.

Sodium chloride solvent 0.9% 5 ml 10 pcs.

Sodium chloride solution 0.9% 200 ml

Sodium chloride solution 0.9% 250 ml

Sodium chloride injection solution 0.9% 5 ml n10 amp

Sodium chloride solvent 0.9% 10 ml 10 pcs.

Sodium chloride solution 0.9% 100 ml

Sodium chloride solution 0.9% 200 ml

Every person at least several times in his life has encountered such an unpleasant disease as a runny nose. Most often, a stuffy nose with p.

Why am I losing weight for no reason? What are the consequences of the disease? Do I need to see a doctor or will it “go away on its own”? Every person should know what...

This question interests a lot of people. If quite recently the bathhouse was considered 100% useful, then recently a number of concerns have appeared, e.g.

What we eat every day begins to worry us at the moment when the doctor makes an unexpected diagnosis of “atherosclerosis” or “ischemic pain.”

Every person can prevent the penetration and development of various infections; the main thing is to know the main dangers that lie in wait.

A smear for oncocytology (Papanicolaou analysis, Pap test) is a method of microscopic examination of cells that are taken from the surface of the skin.

When using materials from the site, the active reference is obligatory.

Source: http://zdorovi.net/preparaty/natrija-chlorid.html

Sodium chloride solution: drug instructions

This drug is widely used in medical practice as a plasma replacement and rehydrating agent. Thus, sodium chloride (NaCl) solution, or saline, is in most cases used to prepare droppers, which are simply irreplaceable for vomiting, poisoning and other syndromes accompanied by a violation of the water-salt balance. Read the instructions for use of this medicine.

Saline sodium chloride solution

In the process of creating this pharmacological composition, salts are introduced into distilled water in a certain way. In this case, each subsequent component is added only after the previous one has completely dissolved. In addition, to prevent sediment from forming in the liquid, carbon dioxide is passed through the sodium bicarbonate. Glucose is added to the solution last. Strict adherence to the specified production technology ensures the preservation of all the beneficial properties of sodium chloride. Depending on the percentage of salts, the following types of solutions are distinguished:

  1. isotonic (9%) – used for preparing injections and droppers.
  2. hypertensive (10%) – used as an auxiliary osmotic diuretic for various serious pathological conditions.

Pharmacological group

According to the classification of medicinal substances, sodium chloride (Natrii chloridum/Sodium chloride) is usually classified as a regulator of water-electrolyte balance and acid-base balance. Due to the fact that the product is used for diluting and dissolving medications, it also belongs to the group of excipients, reagents and intermediates. In addition, some experts classify isotonic sodium chloride solution as an anticongestant - decongestant drug.

Properties

The drug acts as a detoxifying and rehydrating agent. Sodium chloride (NaCl) is used to enrich the body with fluid and increase the volume of circulating arterial blood. This pharmacological effect of saline solution is determined by the presence in it of mineral ions that have the ability to penetrate the cell membrane through a variety of transport mechanisms. According to the pharmacopoeia, sodium chloride helps maintain constant blood pressure and takes part in the electrophysiological processes of the body.

Indications for use

Water-salt balance directly affects the maintenance of the normal state of all organs and systems of the human body. In a normal situation, the NaCl compound enters the body along with food, which is impossible if any pathologies develop. Thus, with vomiting, diarrhea and other similar conditions, there is an increased release of sodium and chlorine ions from the body. This condition is an absolute indication for intravenous sodium chloride.

In addition, the drug is recommended for external use to wash the eyes, nose, and mouth. Separately, it is worth mentioning the benefits of saline solution for treating purulent wounds. The sodium and chlorine salts contained in the preparation have high antimicrobial activity, which is often used by surgeons to prevent the occurrence of postoperative complications. Among other things, the use of NaCl is justified in the following conditions:

  • dyspepsia;
  • poisoning;
  • cholera;
  • constipation;
  • extensive burns;
  • hyponatremia;
  • hypochloremia;
  • forced diuresis;
  • internal bleeding;
  • dehydration.

Instructions for use of sodium chloride

In most cases, saline solution is administered intravenously or subcutaneously. Meanwhile, the use of sodium chloride may involve its entry into the body orally or rectally. As a rule, one or another method of using a drug is determined by the expectation of a certain therapeutic effect. So, in case of severe poisoning, you will agree that it is more logical to use saline solution intravenously than to try to do cleansing enemas.

In general, patients tolerate NaCl well. However, with prolonged use of the drug, overdose effects may be observed: acidosis, extracellular hyperhydration, hypokalemia. In addition, it is important to talk about the specific drug interactions of the solution. Sodium chloride (and its analogs) is compatible with most medications. When diluted with a solution of powdered antibiotics, an increase in their bioavailability is noted. The drug is not recommended to be combined with corticosteroids (Enalapril) and leukopoiesis stimulants (Filgrastim).

For rinsing the nose

Nasal spray based on sodium chloride has a lot of positive properties and almost no side effects. Therefore, sodium chloride for nasal rinsing is used especially widely in pediatric practice to eliminate runny nose in young patients without harm to their health. A saline-based nasal spray is instilled into the nasal passage only after it has been thoroughly cleansed. Adults are recommended to take 2-3 injections three times a day, while for children the indicated dosage should be halved.

Intravenously

In medical practice, parenteral (intravenous) administration of saline is mostly used. For this purpose, the sodium chloride dropper is preheated to 36 degrees. The volume of the administered drug depends on the condition, age and weight of the patient. On average, the daily dose of NaCl should not exceed 500 milliliters. In case of poisoning accompanied by a severe degree of intoxication, the maximum volume can reach 3000 ml. In this case, the rate of infusion (infusion) of the drug is allowed to be increased to 70 drops per minute.

This method of administering saline helps to immediately restore the water-salt balance in the body - this is why sodium chloride is injected intravenously in case of dehydration. In addition, parenteral administration is indicated as plasma replacement therapy and is used for excessively thick blood. It is important to say that saline solution for IVs is often used to dilute any drug that needs to be administered intravenously. In this case, the characteristics of such infusions are determined based on the main medication.

For inhalations

A therapeutic procedure involving inhalation of sodium chloride is indicated for colds. Treatment of infectious pathologies of the respiratory tract is carried out with a combination of saline solution and a bronchodilator. Remember, alkaline (with added salt, soda) inhalations are contraindicated for children under 6 years of age.

Contraindications for sodium chloride

Like any other medicine, NaCl also has some limitations for use. For example, it is prohibited to use saline solution for patients with blood circulation disorders. The fact is that this pathological condition is dangerous due to the development of cerebral edema. For this reason, artificially flooding the body with saline solution during persistent development of circulatory disorders can significantly aggravate the clinical picture of the disease and lead to irreversible consequences. In addition, the use of NaCl is prohibited under the following conditions:

  • pulmonary edema;
  • hypernatremia;
  • hyperchloremia;
  • chronic heart failure;
  • arterial hypertension;
  • acute left ventricular failure;
  • during pregnancy and lactation (breastfeeding).

Sodium chloride price

In pharmacies in Moscow and St. Petersburg, saline solution can be purchased for an average of 30 rubles. At the same time, some private pharmacies, in an effort to compensate for losses, inflate the price of sodium chloride (often with an expired expiration date). For this reason, most of the population today prefers to buy medicines from bona fide virtual sellers. Meanwhile, you can find out the prices for saline solution for IVs in different pharmacies in Moscow below:

Laboratory of Beauty and Health

Laboratory of Beauty and Health

Note!

- The fungus won't bother you anymore! Elena Malysheva tells in detail.

- Elena Malysheva - How to lose weight without doing anything!

Video

Reviews

I used a compress with saline solution when a child developed a boil on his leg. For 4 days before going to bed, I applied gauze soaked in NaCL to my son’s leg and left the bandage on until the morning. The boil broke out on the second day of treatment, after which I applied a compress for several more days to prevent secondary infection of the resulting wound.

I save myself from seasonal exacerbations of rhinitis only with sodium chloride. For this purpose, I buy a special nasal spray at the pharmacy, which I inject into the nasal cavity about 4-5 times a day. As a rule, after 3-4 days of such treatment, the symptoms of rhinitis (stuffiness, runny nose) gradually disappear, and I return to my normal lifestyle.

He underwent intravenous administration of sodium chloride for dehydration due to severe food poisoning. I must say that all my negative conditions disappeared immediately after completing just one infusion. After I found out what sodium chloride is, I consider it simply a salvation for people with signs of poisoning.

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and make recommendations for treatment based on the individual characteristics of a particular patient.

Source: http://sovets.net/13072-natriya-chlorid.html

Sodium chloride

Description current as of 08/03/2015

  • Latin name: Natrii chloridum
  • ATX code: B05XA03
  • Active ingredient: Sodium chloride
  • Manufacturer: Medpolymer, Sintez OJSC, Alium Pharmaceutical Manufacturing Company (Russia), Pharmland JV (Republic of Belarus)

Compound

The active ingredient of this product is sodium chloride. The formula for sodium chloride is NaCl, these are white crystals that quickly dissolve in water. Molar mass 58.44 g/mol. OKPD code - 14.40.1.

Saline solution (isotonic) is a 0.9% solution, it contains 9 g of sodium chloride, up to 1 liter of distilled water.

Hypertonic sodium chloride solution is a 10% solution, it contains 100 g of sodium chloride, up to 1 liter of distilled water.

Release form

A 0.9% sodium chloride solution is produced, which can be contained in ampoules of 5 ml, 10 ml, 20 ml. Ampoules are used to dissolve medications for injection.

A solution of sodium chloride 0.9% is also produced in bottles of 100, 200, 400 and 1000 ml. Their use in medicine is practiced for external use, intravenous drips, and enemas.

Sodium chloride solution 10% is contained in bottles of 200 and 400 ml.

For oral administration, tablets of 0.9 g are available.

A nasal spray is also produced in 10 ml bottles.

pharmachologic effect

Sodium chloride is a drug that acts as a rehydrating and detoxifying agent. The medicine is able to compensate for the lack of sodium in the body, subject to the development of various pathologies. Sodium chloride also increases the amount of fluid that circulates in the vessels.

Such properties of the solution are manifested due to the presence of chloride ions and sodium ions in it. They are able to penetrate the cell membrane using various transport mechanisms, in particular the sodium-potassium pump. Sodium plays an important role in the process of signal transmission in neurons; it is also involved in the metabolic process in the kidneys and in the electrophysiological processes of the human heart.

Pharmacopoeia indicates that sodium chloride maintains constant pressure in the extracellular fluid and blood plasma. In the normal state of the body, a sufficient amount of this compound enters the body with food. But in pathological conditions, in particular, with vomiting, diarrhea, and serious burns, there is an increased release of these elements from the body. As a result, the body experiences a deficiency of chlorine and sodium ions, as a result of which the blood becomes thicker, the functions of the nervous system, blood flow, convulsions, and spasms of smooth muscles are disrupted.

If an isotonic sodium chloride solution is promptly introduced into the blood, its use helps restore the water-salt balance. But since the osmotic pressure of the solution is similar to the pressure of blood plasma, it does not stay in the vascular bed for a long time. After administration, it is quickly eliminated from the body. As a result, after 1 hour, no more than half of the injected amount of solution is retained in the vessels. Therefore, in case of blood loss, the solution is not effective enough.

The product also has plasma-substituting and detoxifying properties.

When a hypertonic solution is administered intravenously, there is an increase in diuresis, replenishing the deficiency of chlorine and sodium in the body.

Pharmacokinetics and pharmacodynamics

Excretion from the body occurs mainly through the kidneys. Some sodium is excreted in sweat and feces.

Indications for use

Sodium chloride is a saline solution that is used when the body loses extracellular fluid. Indicated for conditions that lead to limited fluid intake:

Considering what sodium chloride is, it is used externally to wash wounds, eyes, and nose. The drug is used to moisturize dressings, for inhalation, and for the face.

The use of NaCl is indicated for forced diuresis in cases of constipation, poisoning, and internal bleeding (pulmonary, intestinal, gastric).

It is also indicated in the indications for use of sodium chloride that this is a drug that is used for diluting and dissolving drugs that are administered parenterally.

Contraindications

The use of the solution is contraindicated for the following diseases and conditions:

The solution is prescribed with caution to people who suffer from arterial hypertension, peripheral edema, decompensated chronic heart failure, chronic renal failure, preeclampsia, as well as those diagnosed with other conditions in which sodium retention occurs in the body.

If the solution is used as a diluent for other medications, existing contraindications should be taken into account.

Side effects

The following conditions may develop when using sodium chloride:

If the drug is used correctly, the development of side effects is unlikely.

If a 0.9% NaCl solution is used as a base solvent, then side effects are determined by the properties of the drugs that are diluted with the solution.

If any negative effects occur, you should immediately report it to a specialist.

Instructions for use of Sodium Chloride (Method and dosage)

The instructions for saline solution (isotonic solution) provide for its administration intravenously and subcutaneously.

In most cases, intravenous drip administration is practiced, for which the Sodium Chloride dropper is heated to a temperature of degrees. The volume that is administered to the patient depends on the condition of the patient, as well as the amount of fluid that has been lost by the body. It is important to take into account the person’s age and weight.

The average daily dose of the drug is ml, the solution is administered at an average speed of 540 ml/h. If there is a severe degree of intoxication, then the maximum volume of medication per day can be 3000 ml. If there is such a need, a volume of 500 ml can be administered at a speed of 70 drops per minute.

Children are given a dose of 20 to 100 ml per day per 1 kg of weight. The dosage depends on body weight and the age of the child. It should be borne in mind that with prolonged use of this medicine it is necessary to monitor the level of electrolytes in plasma and urine.

To dilute drugs that need to be administered by drip, use 50 to 250 ml of sodium chloride per dose of the drug. The characteristics of administration are determined based on the main drug.

The hypertonic solution is administered intravenously.

If the solution is used to immediately compensate for the deficiency of sodium and chlorine ions, 100 ml of the solution is injected dropwise.

To perform a rectal enema to induce defecation, 100 ml of a 5% solution is administered; 3000 ml of an isotonic solution can also be administered throughout the day.

The use of a hypertensive enema is slowly indicated for renal and cardiac edema, increased intracranial pressure and for hypertension it is carried out slowly, ml is administered. Such an enema cannot be performed in case of colon erosion and inflammatory processes.

Purulent wounds are treated with a solution according to the regimen prescribed by the doctor. Compresses with NaCl are applied directly to a wound or other lesion on the skin. Such a compress promotes the separation of pus and the death of pathogenic microorganisms.

The nasal spray is instilled into the nasal cavity after it has been cleansed. For adult patients, two drops are instilled into each nostril, for children - 1 drop. It is used for both treatment and prevention, for which the solution is dripped for about 20 days.

Sodium chloride for inhalation is used for colds. To do this, the solution is mixed with bronchodilators. Inhalation is carried out for ten minutes three times a day.

If absolutely necessary, saline solution can be prepared at home. To do this, mix a full teaspoon of table salt in one liter of boiled water. If it is necessary to prepare a certain amount of solution, for example, with salt weighing 50 g, appropriate measurements should be taken. This solution can be applied topically, used for enemas, rinses, and inhalations. However, under no circumstances should such a solution be administered intravenously or used to treat open wounds or eyes.

Overdose

In case of overdose, the patient may feel nausea, suffer from vomiting and diarrhea, he may develop abdominal pain, fever, and rapid heartbeat. Also, in case of an overdose, blood pressure may increase, pulmonary edema and peripheral edema, renal failure, muscle cramps, weakness, dizziness, generalized convulsions, and coma may develop. If the solution is administered excessively, hypernatremia may develop.

With excessive intake into the body, hyperchlorimic acidosis may develop.

If sodium chloride is used to dissolve drugs, then the overdose is mainly associated with the properties of those drugs that are diluted.

If NaCl is inadvertently overadministered, it is important to stop this process and assess whether the patient has any more negative symptoms. Symptomatic treatment is practiced.

Interaction

NaCl is compatible with most medications. It is this property that determines the use of the solution for diluting and dissolving a number of drugs.

When diluting and dissolving, it is necessary to monitor the compatibility of drugs visually, determining whether a precipitate appears during the process, whether the color changes, etc.

When concomitantly prescribing the drug with corticosteroids, it is important to constantly monitor the levels of electrolytes in the blood.

When taken in parallel, the hypotensive effect of Enalapril and Spirapril decreases.

Sodium Chloride is incompatible with the leukopoiesis stimulator Filgrastim, as well as with the polypeptide antibiotic Polymyxin B.

There is evidence that isotonic solution increases the bioavailability of drugs.

When diluted with a solution of powdered antibiotics, they are completely absorbed by the body.

Terms of sale

Sold in pharmacies by prescription. If necessary, use the drug to dilute other medications, etc. write out a prescription in Latin.

Storage conditions

The powder, tablets and solution should be stored in a dry place, in a well-closed container, and the temperature should not exceed 25 degrees Celsius. It is important to keep the drug away from children. If the packaging is sealed, freezing does not affect the properties of the drug.

Best before date

There are no restrictions on storing powder and tablets. The solution in 0.9% ampoules can be stored for 5 years; solution in bottles 0.9% - one year, solution in bottles 10% - 2 years. Cannot be used after the shelf life has expired.

special instructions

If an infusion is given, the patient's condition should be carefully monitored, in particular plasma electrolytes. It should be taken into account that in children, due to immature renal function, sodium excretion may slow down. It is important to determine its plasma concentration before repeated infusions.

It is important to monitor the condition of the solution before administering it. The solution must be transparent and the packaging undamaged. Only a qualified specialist can use the solution for intravenous administration.

Any preparations with Sodium Chloride should only be dissolved by a specialist who can qualifiedly assess whether the resulting solution is suitable for administration. It is important to strictly adhere to all antiseptic rules. Any solution should be administered immediately after its preparation.

The result of a series of chemical reactions involving sodium chloride is the formation of chlorine. Electrolysis of molten Sodium Chloride in industry is a method of producing chlorine. If you carry out electrolysis of a solution of Sodium Chloride, you also end up with chlorine. If crystalline Sodium Chloride is treated with concentrated sulfuric acid, the result is hydrogen chloride. Sodium sulfate and sodium hydroxide can be produced through a chain of chemical reactions. A qualitative reaction to chloride ion is a reaction with silver nitrate.

Analogs

Different drug manufacturers may produce the solution under a separate name. These are the drugs Sodium chloride Brown, Sodium chloride Bufus, Rizosin, Salin Sodium chloride Sinco, etc.

Preparations containing sodium chloride are also produced. These are combined salt solutions of sodium acetate + sodium chloride, etc.

For children

It is used in accordance with the instructions and under the careful supervision of specialists. The immaturity of renal function in children should be taken into account, so repeated administration is carried out only after an accurate determination of plasma sodium levels.

During pregnancy and lactation

During pregnancy, a sodium chloride dropper can only be used in pathological conditions. This is toxicosis in the moderate or severe stage, as well as gestosis. Healthy women receive sodium chloride from food, and its excess can lead to the development of edema.

Reviews

Most reviews are positive, as users write about this product as a useful drug. There are especially many reviews about the nasal spray, which, according to patients, is a good remedy for both the prevention and treatment of a runny nose. The product effectively moisturizes the nasal mucosa and promotes healing.

Sodium Chloride price, where to buy

The price of saline solution in ampoules of 5 ml is on average 30 rubles per 10 pcs. Buying sodium chloride 0.9% in a 200 ml bottle costs an average of rubles for 1 bottle.

  • Online pharmacies in Russia Russia
  • Online pharmacies in Ukraine Ukraine
  • Online pharmacies in Kazakhstan Kazakhstan

WER.RU

ZdravZone

Pharmacy IFC

Pharmacy24

PaniPharmacy

BIOSPHERE

Education: Graduated from Rivne State Basic Medical College with a degree in Pharmacy. Graduated from Vinnitsa State Medical University named after. M.I. Pirogov and internship at his base.

Work experience: From 2003 to 2013 – worked as a pharmacist and manager of a pharmacy kiosk. She was awarded diplomas and decorations for many years of conscientious work. Articles on medical topics were published in local publications (newspapers) and on various Internet portals.

Please tell me how much sodium chloride 0.9% 200 ml should be taken for gargling?

Thank you! Well done for explaining the drug!

Inna: Usually, insomnia occurs for me due to some kind of experience and when you lie down, it’s not.

Olesya: I tried glycine forte, which is more expensive in the price category, but the dosage is the same.

Andrey: Not a word is said about choosing the size of stockings according to a person’s parameters: height, leg size, etc.

Olga: For coxarthrosis of the 2nd degree, I have been injecting for 4 years at the rate (after 6 months), there is no improvement.

All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://medside.ru/natriya-chlorid

Sodium chloride: instructions for use

Sodium chloride is a drug intended for detoxification or rehydration.

Composition, release form

The medication is produced in the form of a clear, colorless solution. 1 liter of medicine contains 9 g of active compound in the form of sodium chloride.

Water for injection is used as additional compounds.

Pharmacological properties

The medication exhibits a rehydrating and detoxifying effect. The drug helps to compensate for the deficiency of the microelement sodium in various diseases and for some time increases the volume of circulating fluid.

The trace element sodium is of great importance in the process of transmitting various signals in nerve cells, takes part in electrophysiological reactions occurring in the heart, and also plays an important role in the metabolic process in the kidneys.

The drug is excreted from the body to a greater extent by the kidneys. A certain amount of the microelement is excreted through sweat and the intestines.

Indications for use

Sodium chloride droppers are prescribed for the following diseases:

  • Lack of trace element sodium;
  • Dissolving or diluting medications that need to be administered parenterally;
  • Extracellular isotonic dehydration.
  • Decreased concentration of the microelement potassium;
  • Excessive fluid content in the body;
  • Acidosis.
  • Use of large dosages of glucocorticosteroids;
  • Left ventricular failure in the acute stage;
  • Acidosis, extracellular hyperhydration;
  • The appearance of circulatory changes indicating the likelihood of developing pulmonary or cerebral edema;
  • swelling of the brain or lungs;
  • Hypernatremia, hyperchloremia, hypokalemia.

Dosage regimen

The medication is prescribed as intravenous drip injections. The dosage is determined by a specialist, taking into account the disease, fluid loss, body weight and age of the patient. In this case, it is necessary to monitor the amount of electrolytes in urine and plasma.

The dosage of the drug for adult patients is 500 ml three times a day.

The dosage of the drug for children is equal to ml per day per 1 kg of body weight.

The dosage that should be used when dissolving or diluting other medications is located in the interval ml per 1 dosage of the administered medication. The rate of administration and dosage is determined according to the recommendations for the use of the administered medication.

Overdose

If the drug is used in a dosage exceeding the therapeutic norm, the following symptoms may appear: increased blood pressure, fever, decreased tear and salivation, pain in the abdomen in the form of cramps, vomiting, tachycardia, sweating, thirst, diarrhea, nausea, pulmonary edema , headache, anxiety, weakness, dizziness, irritability.

In case of overdose, treatment is carried out aimed at suppressing unwanted symptoms.

Drug interactions

The medication combines well with most drugs. Due to this property, it is often used as a base solvent.

Lactation, pregnancy

The medicine is allowed to be prescribed to patients during lactation and pregnancy.

Side effects

The use of the medication may cause the following undesirable effects:

When using the drug as a base solvent for other drugs, the likelihood of developing undesirable manifestations is determined by the characteristics of these drugs. In such a situation, if side effects occur, it is necessary to stop the administration of the medication, assess the patient’s well-being, take the necessary measures and leave the medicine for testing, if necessary.

Contraindications

The medication should not be prescribed in the following situations:

The medication is prescribed with caution to patients suffering from arterial hypertension, peripheral edema, and chronic heart failure.

special instructions

Carrying out any injection with this drug requires monitoring the patient’s well-being, his biological and clinical indicators, special attention should be paid to assessing plasma electrolytes. In a child's body, due to the immaturity of the kidneys, sodium excretion may slow down. In this regard, for such patients, with repeated infusions, the procedure can begin after determining the amount of sodium.

The medicine is allowed to be used only if the packaging is intact and without any foreign matter. Containers should not be connected one at a time, as this may cause an air embolism due to the entry of air remaining in the first package.

The solution must be administered under sterile conditions while observing the basics of antiseptics. To prevent air from entering the infusion system, it must be filled with solution, and the remaining air must be completely released from the plastic packaging.

Other medications may be added during or before the infusion by injection into the area of ​​the package specifically designated for this procedure.

After one use, the packaging must be disposed of. Any unused dose should also be discarded.

You cannot reconnect incompletely used containers (regardless of how much medicine is left in it).

The effect of the medication on the ability to drive vehicles and operate complex machinery has not been described.

The average cost of the drug Sodium chloride in Moscow is 26 rubles.

Analogs

Analogs of the drug Sodium chloride in terms of pharmacological properties are: Physiological solution "Fiziologika", Physiodoza, Salin, Rizosin, Sodium chloride-Senderesis, Sodium chloride bufus, Sodium chloride Brown, Sodium chloride Bieffe, Aqua-Rinosol.

Terms and conditions of storage

The medication is stored at a temperature of no more than 25 degrees C in a place away from small children. The medicine is allowed to be used for 1.5 years for a volume of 50 ml, for 2 years for a volume of 100 ml and for 3 years for a volume of 500, 250 ml or 1 liter.

Source: http://bezboleznej.ru/natriya-chlorid