Is it possible to take ingavirin for more than 7 days?

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How to take Ingavirin - instructions for use

Ingavirin is a modern antiviral drug. Below are detailed instructions for using Ingavirin, containing information about the forms of release, composition and administration of the drug.

Table of contents:

Release form: Available in the form of red and blue capsules in a gelatin shell.

Ingavirin - composition of the drug

  1. Blue capsules are size No. 2, contain granules and white or slightly creamy powder. One capsule contains:
  • imidazolylethanamide pentanedioic acid (vitaglutam) - 30 milligrams;
  • Excipients.

The gelatin shell contains a dye that gives it a blue color. There are 7 capsules in a blister pack.

  1. Red capsules are size No. 1, contain granules and white or slightly creamy powder. One capsule contains:
  • imidazolylethanamide pentanedioic acid (vitaglutam) - 90 milligrams;
  • Excipients.

The gelatin shell contains a dye that gives it a red color. There are 7 capsules in a blister pack.

Pharmacodynamics

A modern antiviral drug with a wide spectrum of action. Effective against influenza viruses type A, including swine flu and type B, pathogens of acute respiratory diseases (adenovirus infection, parainfluenza, respiratory syncytial infection). Ingavirin for the prevention of influenza is an effective remedy. Acts at the nuclear level, suppressing the replication of the virus. Stimulates the production of its own interferon. Positively affects cellular immunity due to:

  • increasing the number of NK-T cells, which have a high degree of damaging effect on cells modified by viruses and pronounced antiviral activity;
  • formation of cytotoxic lymphocytes.

The anti-inflammatory effect is achieved by suppressing the formation of cytokines and inflammation (TNFα, IL-1β and IL-6), reducing the degree of myeloperoxidase activity.

The positive therapeutic effect is expressed by:

  • reducing the duration of fever;
  • to reduce the severity of intoxication syndrome, accompanied by severe weakness, dizziness and headaches;
  • in reducing catarrhal symptoms;
  • in reducing the duration of the disease;
  • reducing the risk of complications.

It has a high degree of safety due to low toxicity. The lethal dose exceeds the therapeutic dose by more than 3000 times.

The drug does not have mutagenic, immunotoxic, allergenic or carcinogenic properties, and does not have a local irritant effect. Therefore, doctors' reviews of Ingavirin are good.

Pharmacokinetics

When it enters the gastrointestinal tract, it is quickly absorbed and, entering the blood, is distributed throughout the body. The maximum concentration of the drug is reached approximately half an hour after administration. Complete elimination of the drug is observed within an hour. When treated for five days (take 1 capsule per day), the concentration in the blood increases sharply immediately after administration and then slowly decreases throughout the day.

It is practically not absorbed in the human body and is excreted unchanged within 24 hours. Excretion from the body occurs mainly through the intestines with feces and to a lesser extent by the kidneys with urine.

The scope of the drug in therapeutic practice is extensive. For treatment and prevention:

  • influenza type A, including swine flu;
  • influenza type B;
  • acute respiratory diseases (adenovirus infection, parainfluenza, respiratory syncytial infection).

Instructions for use and dosage

It is recommended to start taking the drug on the first or second day of the disease. It is better to take it immediately at the first symptoms of infection. The drug is taken orally, 90 mg tablet. once a day, regardless of food intake. The course of treatment is 5-7 days (depending on the individual course of the disease and its severity).

Treatment of any viral disease must be comprehensive. An obligatory point is to influence the cause of its occurrence. This is achieved through the use of the antiviral drug Ingavirin 90 mg, or Ingavirin 60 mg (children's Ingavirin), or its substitutes. The treatment regimen also includes drugs that block symptoms and general restorative therapy.

Ingavirin is non-toxic, well tolerated by most patients and has no negative effects. In case of individual intolerance to the components of the medication, some patients may develop allergic reactions.

Contraindications to the use of the drug

Contraindications include:

  • pregnancy and breastfeeding;
  • age under 18 years;
  • the presence of individual intolerance to the components of the drug.
Use of the drug during pregnancy and lactation

Ingavirin has no toxic effect on the embryo, on reproductive function, and also has no teratogenic effect. But this issue has not been thoroughly studied. No clinical studies have been conducted.

To avoid negative consequences, the drug is contraindicated in pregnant women. If an infection develops and it is necessary to treat with the drug during breastfeeding, it is necessary to temporarily switch to artificial feeding.

Can I take it while driving?

Has no effect on the central nervous system. Therefore, it does not impair the ability to drive a car and can be taken when working with complex mechanisms.

Ingavirin does not have a sedative effect, does not change the psyche and reaction speed, the drug can be prescribed to persons of any profession, including those requiring concentrated attention and coordination of movements.

Practically and theoretically impossible. Similar cases have not been described.

You should not combine the use of Ingavirin with other antiviral drugs. There will be no enhancement of the therapeutic effect, and the risk of toxic effects increases.

There is no description of interactions with medications from other drug groups.

Average prices for the drug

  • Русский
  • Ingavirin for children in capsules of 60 milligrams, 7 capsules per package - about 413 rubles per package.
  • Ingavirin in capsules of 60 milligrams, 7 capsules per package - about 511 rubles per package.

Absolutely forbidden. The reason is that a chemical interaction between alcohol and the active substance of the drug occurs in the body. As a result, the effect of taking the medication is sharply reduced and the therapeutic effect is not achieved.

In addition, Ingavirin interferes with the metabolism of alcohol by the liver and enhances its damaging effects. Any alcoholic drinks neutralize the therapeutic effect of Ingavirin and act more harshly on the liver. Alcoholic drinks can be drunk only three days after taking the last capsule of the drug.

Analogs

Drugs containing the same active substance in the same doses are not produced. The only drug that contains vitaglutam is Dicarbamine.

But it has a different scope. It is used in oncological practice to eliminate complications from impaired hematopoiesis in patients undergoing chemotherapy. It contains high dosages of the active substance and is expensive. It would be wrong to classify it as an analogue of Ingavirin.

Ingavirin has a replacement only for its therapeutic effect. These are products with a different composition, but they cause the same effect when used.

Cheap analogues of Ingavirin - names and average prices:

  1. Amizon – 195 – 254 rubles;
  2. Arbidol – 150 – 250 rubles;
  3. Hyporamine – 120 – 160 rubles;
  4. Kagocel – 210 – 240 rubles;
  5. Oksolin 20 – 60 rubles;
  6. Ergoferon – 250 – 390 rubles.

Ingavirin for children

Any doctor will confirm the fact that children tolerate viral infections worse. They have a more frequent occurrence of ARVI, especially in autumn and winter, a more severe course of the disease itself, and a high percentage of the risk of developing severe complications. Therefore, the prescription for young patients begins at the age of thirteen. Ingavirin helps speed up recovery and avoid extremely unwanted complications.

For prevention and treatment from the age of thirteen, Ingavirin is taken 60 mg (2 capsules) once a day at the same time. The sooner treatment is started from the onset of the disease, the better the result will be.

This drug is not recommended for children under 13 years of age. According to the instructions for use of Ingavirin, it is better not to use the drug itself and its analogues until the age of eighteen.

The main advantages of Ingavirin

Ingavirin as an antiviral agent satisfies all points of compliance that are taken into account to evaluate modern drugs used for the treatment and prevention of the development of colds and infectious diseases during their seasonal increase. It is effective in preventing the development of the disease in persons who have had contact with already sick people. Ingavirin acts against swine flu, which is extremely dangerous with complications.

Effective against many viruses that cause both influenza and acute respiratory diseases.

The next positive characteristic of this antiviral agent is the low risk of viruses developing resistance to it during treatment. The drug is well tolerated by most patients due to its low toxicity. The manufacturer promises a minimum of side and undesirable effects as a result of use, subject to the instructions for use of Ingavirin.

Judging by the results of clinical studies, it can be argued that the antiviral drug Ingavirin is truly effective in the treatment of swine flu. The main thing is to take it according to the instructions for use of Ingavirin. Early treatment on the first or second day from the onset of the infectious process promotes faster recovery, shorter duration of the disease and an easier course.

The period during which the body temperature remains high is sharply reduced, and the intoxication syndrome is less pronounced. The lungs and bronchi are less affected, which is reflected in a shorter period of cough in the patient. Treatment with Ingavirin also reduces the incidence of complications resulting from the development of secondary infection.

Let's summarize all of the above:

  • it is necessary to start treatment as early as possible;
  • is the drug of choice in older people with concomitant chronic diseases of the respiratory system.
Ingavirin in the treatment of ARVI complicated by angina

The effectiveness and benefits of using a combination of Ingavirin and antibiotics in combination therapy is manifested in a reduction in the severity and duration of symptoms of the disease, such as fever, symptoms of intoxication, manifested in weakness and headache, discomfort in the throat and pain when swallowing, as well as purulent plaque.

All this contributes to a faster recovery, reducing the duration of taking antibiotics and reducing the length of time patients spend in hospital. The combination of antibiotics and ingavirin has antiviral and anti-inflammatory effects, which has significant advantages over standard therapy. Ingavirin can be safely recommended to a patient in case of a diagnosis of a viral infection complicated by a sore throat. Reviews for Ingavirin are usually only positive.

Which is better Kagocel or Ingavirin?

To successfully treat any viral disease, an antiviral drug must be included in the treatment regimen. Which one should you give preference to? Ingavirin and Kagocel are more popular among patients and doctors. So which medication is better?

Both drugs have an antiviral effect and are produced by domestic manufacturers. They are produced in dosage forms for oral administration and contain the active substance and excipients. A distinctive feature of Kagocel is the plant origin of the active substance included in its composition.

Which drug has the most effective antiviral effect? Kagocel does not act directly on the virus. It only strengthens the immune system, which allows the body to fight infection more effectively. Its prescription is not affected by the type of virus and its resistance to treatment. As a result of prescribing the drug, the severity of the disease is reduced and recovery is accelerated. This drug is more suitable for prevention during an epidemic.

Ingavirin, in addition to enhancing immunity, has a direct antiviral effect on many viruses and prevents their reproduction in the body. Therefore, it is effective for already developed disease.

Ingavirin and Kagocel have similarities in terms of indications and contraindications for use. It is not recommended to give to children: Kagocel - up to three years of age, Ingavirin - up to 13 years of age. These drugs are also contraindicated in case of hypersensitivity to the components of the drug, pregnancy and lactation.

What is more affordable - Kagocel or Ingavirin?

The cost of Kagocel (a package of 10 tablets) costs between 220 and 234 rubles, and for a course of treatment for an adult patient it requires 2 packages (this is 18-20 tablets). As a result, you need to spend about 450 rubles. A package of Ingavirin 90 mg, containing 7 capsules, sufficient for a course of treatment, has approximately the same cost - rubles.

Reviews about the application

I rarely get sick. But at the end of the epidemic, she still caught the virus and fell off her feet. Typical symptoms of a cold appeared: runny nose, weakness, high fever and headaches.

The local doctor confirmed the diagnosis - an acute respiratory disease, and prescribed Ingavirin one capsule per day at the same time for five days. After the first capsule taken at night, in the morning I felt an improvement in my condition. I can note the ease of use. This drug helped me recover quickly. I didn’t stay on sick leave too long and didn’t suffer any complications.

Lisa, 28 years old - Ekaterinburg

Review #2

I often get colds, especially in the fall and winter seasons. The disease usually occurs with a full range of standard symptoms. Typically, with a traditional treatment complex, improvement in well-being occurred within 10 or 14 days.

A friend advised me to take Ingaverin. I was able to buy it at the nearest pharmacy, although I did not have a prescription. I read the instructions for using Ingavirin. I took one capsule for a week. There was a noticeable effect already on the third day. For a mild cold, I take it for a couple of days. A good and quick effect allows you not to go on sick leave.

Veronica, 37 years old - Krasnoyarsk

Review #3

I got sick, catching a cold. I didn’t want to go to the clinic. I sent my husband to the pharmacy, where the pharmacist advised me to take Ingavirin. I read the instructions. Strictly as recommended, I took 1 capsule for seven days. No significant effect was noted. The course of the cold was no different from the acute respiratory viral infections that had previously happened to me, treated with other means. I think that I spent a lot of money in vain.

Karina, 41 years old - St. Petersburg

Review No. 4

I'm not a fan of writing reviews. But Ingavirin pleased me very much with its effectiveness. A year ago, a cold I caught was complicated by bronchitis. Despite the long and intensive treatment, the annoying cough went away only with the onset of warm weather outside closer to summer. This year, without having time to see a doctor, I went to the nearest pharmacy. There they advised me to buy Ingaverin. After reading the instructions for using Ingavirin, I followed all the recommendations for taking it. I took one capsule at the same hours for seven days. The condition quickly improved; the cough did not complicate the disease. I was very pleased.

Reviews from doctors on Ingavirin

A wonderful drug. Has proven itself well in practical application. We cannot replace Ingavirin for the prevention of influenza. Tolerated by the patient without undesirable effects. It is not toxic at all and has no unwanted effects.

If patients follow all the recommendations and begin treatment on time, then recovery occurs much faster, the period of temporary disability does not prolong, and cases complicated by the development of pneumonia are less frequently identified. The only negative is the rather high price. Not all patients can buy the medicine without compromising their budget.

Victor Abramovich, doctor with 20 years of experience - Moscow

Ingavirin is a drug with combined action. It improves immunity by acting at the cellular level. It prevents the viruses themselves from multiplying and contributes to the rapid disappearance of the symptoms of the disease.

It is important to start treatment as early as possible and strictly follow the instructions. This is an excellent assistant in the fight against epidemics of influenza and acute respiratory diseases. There is no development of pathogen resistance, which is also very important.

Victoria Sergeevna, 43 years old, doctor of the highest category - St. Petersburg

I don’t take medications often, but this winter I got seriously ill. And yet I decided to try to be treated as expected. At the clinic they prescribed Ingavirin, I remember being surprised that there were so few pills in the package. Then I realized, just for one course. I drank everything, although I really could have had three drinks and stopped; on the fourth day, even the cough and runny nose were almost not felt. But I was afraid of complications and finished the rest. As a result, on the fifth day I was ready to go to work.

I started taking ingavirin 90 mg once for body aches, weakness, dryness and sore throat and slight fever. I was captivated by the fact that, unlike many other similar drugs, with 2 tablets taken up to 5 times a day, here it is taken once, regardless of food. There was no immediate relief, on the contrary, nasal congestion appeared, then a runny nose, but by the fifth day it became much better: the headache and weakness, aches and pains disappeared, the temperature became normal. In seven days I recovered completely.

When I fell ill with ARVI, I was treated with Ingaverin on the doctor’s recommendation. I took it one tablet a day. Already on the 3rd day I felt much better and I was able to get back on my feet. To be precise, I decided to finish this drug to the end. And as a result, after a week I was completely cured, all the symptoms of the disease disappeared. In general, the drug is excellent, the most effective compared to analogues.

If I get sick, I take Ingavirin because I like it more than other drugs. It has a noticeably quick effect on the symptoms of the disease, although the instructions do not seem to say that it is against the symptoms. I understand that the symptoms go away because from the first day its antiviral effect is already felt. I get sick often, so Ingavirin has become a reliable friend for me lately. Previously, I stayed at home for at least a week and then recovered for a long time, now on the third or fourth day I can already work calmly.

I agree with everyone, a good drug. It’s the only thing I’ve been taking lately to treat ARVI. Previously, I called a doctor at home every time to understand how to be treated, but now I always have this medicine in the medicine cabinet, so I take it right away. Of course, I still call the doctor, but usually it all ends with him telling me after the examination: well done, you’re doing everything right!

I also treat ARVI with Ingavirin. The first time the doctor prescribed it to me, now I keep it in my first aid check just in case. So if I get sick, I immediately drink a capsule and try to drink more and sleep. It turns out that the next day you feel much better. I usually take a course of 5 tablets, but if I get very sick, I take the whole pack, just to be sure.

About a year ago, something like this happened to me... I got seriously ill with ARVI.... It was just brutal - my throat was just torn...=(((((((The pharmacy recommended Ingavirin - they said it was a reliable remedy. So I bought it. I decided to try it, drank the first capsule - I felt better in just a couple of hours. The second and subsequent ones were taken exactly according to the schedule. On the fourth day I was completely relieved)) and I was able to go for a quiet walk. I finished the course to definitely finish off the damned viruses... Something like that xD

The doctor prescribed ingavirin for the flu, on the third day I seemed to feel better, the temperature subsided, but the condition was painful, and I suffered with such a painful condition for a week, and then I jumped into my forties, they called an ambulance, it turned out to be pneumonia. Here's a super medicine for you.

I would not say that Ingavirin is a super medicine. Has not undergone full placebo-controlled studies. There are no foreign analogues; it is not used anywhere else in the world for ARVI. So there is nothing to expect from anyone.

A very convenient medicine for doctors, the course of treatment with ingavirin is 5-7 days, as we know during this time a person is able to recover on his own, which is why there are so many “healthy” people who have been helped by ingavirin))

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Source: http://glavvrach.com/ingaverin/

"Ingavirin": reviews from specialists. "Ingavirin 90": instructions for use

A new innovative antiviral drug is the drug “Ingavirin”. Reviews about this medicine are mixed. Some people find this medication very effective, while others describe it as a little-studied drug with very questionable effectiveness. What do experts think about this drug? You will learn about this from our article.

Indications

The drug "Ingavirin", reviews of which will be presented in this article, is a drug with a pronounced antiviral effect. It is taken to combat influenza A (H1N1, H3N2, H5N1, etc.), influenza B, adenovirus, parainfluenza and respiratory syncytial infections. Thus, this domestic medicine has a very wide spectrum of action, which arouses close medical interest in it.

Mechanism of action

A strong medicine is the drug "Ingavirin". Reviews from patients indicate that it quickly relieves fever and other unpleasant symptoms of the flu. This effect is associated with the mechanism of action of the drug. "Ingavirin" affects viruses by suppressing their ability to reproduce (divide). The well-known Swiss drug Teraflu has a similar effect. However, the domestic “Ingavirin” is capable of more: it has a stimulating effect on the synthesis of interferons, and also gives a pronounced anti-inflammatory effect. In this case, the medicine is not retained in the body, but is eliminated from it within 24 hours after administration.

Composition and analogues

Many doctors strongly advise patients to take the drug Ingavirin. Feedback from experts indicates that in the presence of this medication, the patient’s body becomes more viable, synthesizes a sufficient number of protective factors and can resist viral infection. What makes this medicine so effective? It is based on a complex chemical compound called “vitaglutam”. It has a beneficial effect on the activity of the circulatory system. The same substance is contained in the drug “Dicarbamin”, which is used to fight cancer and to protect the blood during chemotherapy. What could a cure for cancer and a cure for the flu have in common? It turns out that there is nothing surprising in this fact. The fact is that the dosages of vitaglutam in medications are not the same, and the fact that different amounts of medication taken can have different effects on the body is no secret. Another drug with a similar mechanism of action on the body is Vitaglutam. It is proposed to be used to improve the process of hematopoiesis (that is, to accelerate the formation and maturation of blood cells). Thus, the substance from which the medicine “Ingavirin” is made has been used in medicine for a long time and has been successfully used. Analogues of this drug (according to the method of action) are the drugs “Dicarbamin” and “Vitaglutam”. However, these medications are powerless against viruses.

Release forms

The medication is available in capsules that differ from each other in the content of the main active ingredient.

The drug "Ingavirin 90", reviews of which are mostly positive, is presented in the form of red capsules. Each shell contains 90 milligrams of active substance. In packages with the drug you can find 7 or 90 similar capsules. Inside they are granules and white powder.

The blue capsules contain significantly less vitaglutam. They contain only 30 milligrams of active ingredient, the rest of the volume is occupied by auxiliary components (starch, lactose and others). The medicine is a white homogeneous powder. Packages with the drug "Ingavirin" contain from 7 to 90 blue capsules.

Instructions for use

Many patients are interested in the drug "Ingavirin" (instructions for use, reviews). The annotation for this medicine states that it should be taken one capsule of 90 milligrams once a day, the course is 5-7 days. The first dose must be taken within thirty-six hours from the moment the first symptoms of the disease appear. Capsules should be swallowed completely with the required amount of water. Many people are interested in whether children can take the medicine Ingavirin. Reviews from experts indicate that the drug has not yet become widespread in pediatrics, and is therefore not recommended for persons under eighteen years of age. However, over time, the age range for taking the medicine is planned to be expanded.

Contraindications

During pregnancy and lactation you should not take the drug Ingavirin. Reviews about taking the medication do not contain any negative information, but the medicine has not yet been studied enough and therefore needs further testing. For the same reason, the drug is not recommended for children. Individual intolerance to individual components also serves as a signal that the use of the medicine is inappropriate.

Overdose and side effects

You don't have to be afraid of an overdose when you take Ingavirin. Reviews from experts confirm this. The fact is that the toxic dose of the drug is 3000 times higher than the therapeutic dose. No one can take this amount of medicine. As for side effects, only allergic reactions were noted among them. The annotation for the medication says that they are extremely rare.

Drug safety

The drug Ingavirin 90 is relatively safe. Reviews from experts strongly advise using this drug against the most severe forms of influenza. Doctors justify their position with the following facts:

  1. This medication significantly reduces the risk of relapses and complications.
  2. Taking the medicine does not depend in any way on the diet.
  3. The drug "Ingavirin" has a proven safety profile.
  4. The drug does not have a local irritant, allergenic, immunotoxic, or mutagenic effect on the body.
  5. The medication does not have reproductive toxicity or carcinogenic activity.
  6. The drug Ingavirin is recommended by the Ministry of Health and Social Development for the treatment of swine flu. Instructions and reviews of the medicine indicate its high effectiveness against this disease.

Interaction with other drugs

It has not been fully studied how Ingavirin interacts with other drugs. Reviews from scientists state that this medication does not react in any way to the presence of other drugs in the human body. However, it is better for patients to be on the safe side, especially since the combination of different antiviral drugs usually does not lead to a significant increase in the therapeutic effect, and the frequency of side effects, on the contrary, may increase.

Evidence base

In 2009, the drug Ingavirin was tested in humans. Reviews of the study indicate that the medication significantly reduces the duration of fever during influenza (duration - 34.5 hours). This figure is much lower than when using the advertised Arbidol (48.4 hours) or taking a placebo (72 hours). Another result of the trial was the absence of toxic effects when using the drug. Unfortunately, there is no other official evidence of the effectiveness of the drug yet. However, many praise Ingavirin. Reviews from specialists on specialized forums indicate that its effectiveness has been confirmed by practice. Below we will talk about what patients think about this medication.

Patient reviews

The medicine Ingavirin helped many. Reviews from some patients indicate that already on the second day of using the drug, their condition significantly improved and their temperature decreased. Some say that the very next day after taking the capsules they felt completely healthy, but they did not stop the course of treatment and did not feel any unpleasant consequences. There are also reviews that three weeks after using the medicine, some patients became infected with influenza again, but the disease was milder.

However, not everyone tolerates the antiviral drug Ingavirin equally well. Reviews from patients also contain information that the medicine caused heartburn, stomach pain and attacks of dizziness in some. Apparently, such symptoms are associated with the individual characteristics of the body. There may be an allergic reaction to certain components of the drug. One way or another, such comments exist, and they are worth taking into account.

There is a third opinion about the drug "Ingavirin". Reviews from some patients indicate that the medicine did not have any pronounced effect on them. They say that within the recommended time of taking the drug (five to seven days), the body itself can easily cope with the flu, and “miracle” capsules only help drug manufacturers, and not in terms of health, but in terms of material well-being. Such patients expect immediate action from an antiviral drug, forgetting that each of us has individual characteristics, and, unfortunately, panaceas for all possible influenza viruses have not yet been invented.

In general, patients have good impressions after using the drug Ingavirin. Medical experts also leave similar reviews. This antiviral remedy has not yet been tested by time, but has already won loyal supporters. However, any new medication should be taken with caution. Remember this and be healthy!

Similar articles

I started taking it when the cold had already started.

Previously, there was experience of taking ingaverin during an epidemic for prevention - it did not protect against colds, perhaps the form of the course was milder than it would have been without taking the drug.

Just two steps and you feel like a person, and not some kind of vegetable.

Source: http://www.syl.ru/article/177308/new_ingavirin-otzyivyi-spetsialistov-ingavirin-instruktsiya-po-primeneniyu

Ingavirin - instructions for use, reviews, analogs and release forms (capsules 30 mg, 60 mg and 90 mg) of the drug for the treatment of influenza and ARVI in adults, children and pregnancy. Compound

In this article you can read the instructions for use of the drug Ingavirin. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Ingavirin in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Ingavirin in the presence of existing structural analogues. Use for the treatment of influenza and ARVI in adults, children, as well as during pregnancy and lactation.

Ingavirin is an antiviral drug. Active against influenza viruses type A (A/H1N1, including “swine” A/H1N1 swl, A/H3N2, A/H5N1) and type B, adenovirus infection, parainfluenza, respiratory syncytial infection.

The antiviral mechanism of action is associated with the suppression of virus reproduction at the nuclear phase, delaying the migration of newly synthesized NP virus from the cytoplasm to the nucleus.

It has a modulating effect on the functional activity of the interferon system: it causes an increase in the interferon content in the blood to the physiological norm, stimulates and normalizes the reduced alpha-interferon-producing ability of blood leukocytes, stimulates the gamma-interferon-producing ability of leukocytes.

Causes the generation of cytotoxic lymphocytes and increases the content of NK-T cells, which have high killer activity against virus-transformed cells and pronounced antiviral activity.

The anti-inflammatory effect is due to the suppression of the production of key pro-inflammatory cytokines (TNF-alpha, IL-1beta and IL-6), and a decrease in the activity of myeloperoxidase.

Therapeutic effectiveness for influenza and other acute respiratory viral infections (ARVI) is manifested in a shortening of the period of fever, a decrease in intoxication (headache, weakness, dizziness), catarrhal phenomena, a decrease in the number of complications and the duration of the disease.

When used in recommended doses, determination of the drug in blood plasma using available methods is not possible. In experimental studies using a radioactive label, it was found that the drug quickly enters the blood from the gastrointestinal tract and is evenly distributed throughout the internal organs. With a 5-day course of oral administration of the drug once a day, it accumulates in internal organs and tissues. It is not metabolized in the body and is excreted unchanged. The main elimination process occurs within 24 hours. During this time, 80% of the dose is eliminated. Of these, 77% is excreted in feces and 23% in urine.

Pentanedioic acid imidazolylethanamide (vitaglutam) + excipients.

  • treatment of influenza A and B and other acute respiratory viral infections (adenoviral infection, parainfluenza, respiratory syncytial infection).

Capsules 30 mg, 60 mg and 90 mg.

The tablet form does not exist in nature; perhaps the drug in this form is a counterfeit of the original Ingavirin.

Instructions for use and dosage regimen

The drug should be taken orally, regardless of food intake, 90 mg 1 time per day for 5-7 days (depending on the severity of the condition).

The drug should be taken from the moment the first symptoms of the disease appear, preferably no later than 36 hours from the onset of the disease.

For the treatment of influenza and acute respiratory viral infections, children aged 7 to 17 years are prescribed 1 capsule (60 mg) once a day. Duration of treatment is 5-7 days (depending on the severity of the condition). The drug should be taken from the moment the first symptoms of the disease appear, preferably no later than 2 days from the onset of the disease.

  • pregnancy;
  • children up to 7 years of age (for 60 mg capsules), children and adolescents up to 18 years of age (for 90 mg capsules);
  • lactase deficiency, lactose intolerance;
  • hypersensitivity to the components of the drug.

Use during pregnancy and breastfeeding

The use of the drug during pregnancy has not been studied.

If it is necessary to use the drug during lactation, the issue of stopping breastfeeding should be decided.

Ingavirin does not affect reproductive function and does not have embryotoxic or teratogenic effects.

Experimental toxicological studies conducted indicate a low level of toxicity and a high safety profile of the drug (LD50 exceeds the therapeutic dose by more than 3000 times).

The drug does not have mutagenic, immunotoxic, allergenic or carcinogenic properties, and does not have a local irritant effect.

Regarding the joint use of the drug and alcohol, standard recommendations apply, or rather a ban on simultaneous use. The combined effect of ethanol and Ingavirin has not been studied.

Impact on the ability to drive vehicles and operate machinery

Ingavirin does not have a sedative effect, does not affect the speed of the psychomotor reaction, the drug can be used by people of various professions, incl. requiring increased attention and coordination of movements.

The simultaneous use of Ingavirin with other antiviral drugs is not recommended.

No cases of interaction of Ingavirin with other drugs have been identified.

Analogues of the drug Ingavirin

Structural analogues of the active substance:

According to the mechanism of action (antiviral effect):

Similar medications:

Other medicines:

News edited by: admin016, 23:38

Source: http://instrukciya-otzyvy.ru/167-ingavirin-po-primeneniyu-analogi-kapsuly-gripp-orvi-u-vzroslyh-detey-pri-beremennosti.html

Ingavirin - instructions for use, composition, indications, analogues and reviews

Ingavirin is an antiviral drug that is active against influenza viruses types A and B, adenovirus infection, parainfluenza, and respiratory syncytial infection. The antiviral effect of the drug Ingavirin is associated with the suppression of virus reproduction at the nuclear phase, delaying the migration of the newly synthesized NP virus into the nucleus from the cytoplasm.

Composition and release form

Ingavirin is available in the form of capsules of 7 pieces in a blister pack. The cardboard package contains 1 blister. According to the instructions, Ingavirin should be stored in its original packaging in a place protected from sunlight and out of the reach of children. The room temperature should be °C. According to the instructions, the shelf life is 2 years from the date of manufacture indicated on the packaging.

The medicine contains the following components:

  • Active ingredient: Pentanedioic acid imidazolylethanamide (90 mg);
  • auxiliary components – lactose, potato starch, colloidal silicon dioxide, magnesium stearate;
  • the shell contains: titanium dioxide, diamond black dye, patented blue dye, azorubine, crimson dye, gelatin.

Ingavirin instructions for use of the drug

Capsules should be taken orally with a small amount of water. Taking the medicine does not depend on food intake. To maximize the effectiveness of treatment, treatment should begin when the first symptoms of the disease appear. It is recommended to start treatment no later than 1.5 days after the first symptoms of the disease appear.

In most cases, the daily dosage of Ingavirin is 1 capsule per day. The duration of the course of using Ingavirin is prescribed by the doctor in each case individually. When treating viral infectious diseases, 1 capsule per day is prescribed. The duration of treatment when using the medication is 5-7 days.

For preventive purposes against viral respiratory infections after contact with a patient, it is recommended to use 1 capsule per day for 7 days.

The use of the drug Ingavirin in the treatment of influenza

Today there are no drugs that could completely protect the body from influenza, but there are drugs that can relieve these symptoms at the first sign of it.

One of these drugs is Ingavirin, which suppresses the development of a viral infection. It shows high effectiveness against respiratory syncytial and adenoviral infections, as well as influenza types A and B. Ingavirin does not cause complications and is a safe drug that is excreted unchanged by the body throughout the day.

If the drug is started no later than 36 hours after the first symptoms of influenza appear, the effectiveness of treatment will be high.

Indications, contraindications, side effects of Ingavirin

Ingavirin is part of the complex therapy of patients who suffer from respiratory tract diseases caused by viruses that are sensitive to the active ingredient of the drug.

Indications for use of Ingavirin

  • influenza type A, B;
  • adenoviral infection;
  • parainfluenza;
  • respiratory syncytial infections.

In addition, Ingavirin is also prescribed as a prophylactic against respiratory viral infections and influenza, if the risk of possible infection is high. It is recommended to use the drug immediately after contact with the patient.

Contraindications for the use of Ingavirin

According to the instructions, contraindications to the use of the drug Ingavirin are:

  • hypersensitivity to the active substance or auxiliary components of the drug;
  • pregnancy;
  • children and adolescents under 18 years of age.

Ingavirin: symptoms of overdose

There is no information regarding cases of overdose of Ingavirin.

Side effects from using Ingavirin

In most cases, the drug is well tolerated by the body. In isolated cases, allergic reactions may occur in people with hypersensitivity.

How to use Ingavirin

The research results showed that the toxicity of the drug is low, and its safety profile is high. The medicine does not have a local irritant effect, does not exhibit mutagenic, immunotoxic, allergenic or carcinogenic effects. The drug does not exhibit a sedative effect and does not affect psychomotor reactions. The drug can be used by people whose occupation requires concentration.

How long can Ingavirin be used?

The duration of treatment with Ingavirin or taking the drug for preventive purposes is determined by the doctor, based on the general condition of the patient and the severity of the disease individually in each individual case.

Recommendations for the use of Ingavirin during pregnancy

There is no confirmed data regarding the use of the drug during pregnancy. As for the period of breastfeeding, it will have to be stopped during the period of treatment with Ingavirinm. If there is a need to use the product during pregnancy or during breastfeeding, you should definitely consult a doctor to avoid possible negative consequences for the woman and the fetus or baby.

How to use correctly: Ingavirin dosage regimen for children

There are contraindications for the use of the drug in childhood, as well as in adolescents under 18 years of age.

Interaction of the drug Ingavirin with other drugs

It is not recommended to use Ingavirin simultaneously with other drugs that have an antiviral effect.

Chemical composition and therapeutic effects of Ingavirin

The medicine has a modulating effect on the functional activity of the interferon system: the level of interferon in the blood increases to the physiological norm, the reduced β-interferon-producing ability of blood leukocytes is stimulated and normalized, and the g-interferon-producing ability of leukocytes is stimulated.

The use of the drug generates cytotoxic lymphocytes and increases the level of NK-T cells, which have high activity against cells transformed by viruses, as well as pronounced antiviral activity. The anti-inflammatory effect is due to the suppression of the products of the main pro-inflammatory cytokines and a decrease in the activity of myeloperoxidase.

The therapeutic effectiveness of the drug for influenza and other acute respiratory viral infections is manifested in a decrease in the febrile period; reducing intoxication, which is manifested by symptoms such as severe weakness, headache, dizziness; catarrhal phenomena, reducing the number of complications and duration of the disease.

If the drug is used in the dosage specified in the instructions, then its concentration in the blood plasma is not determined. Based on research results, it was found that the drug quickly enters the blood from the gastrointestinal tract, evenly distributed throughout the internal organs. The highest concentration in blood plasma is achieved half an hour after consuming the drug. On average, the drug remains in the blood for 37 hours.

During the course of treatment, which consists of taking the drug Ingavirin at a dosage of 1 tablet per day for 5 days, Ingavirin accumulates in tissues and organs. The medicine is not metabolized, but is excreted from the body in its original form. The drug is predominantly eliminated from the body within two days after taking the drug, when 80% of the dose taken is eliminated, 77% of this amount is excreted in feces, and 23% in urine.

Ingavirin analogues: domestic and foreign

The medicine has many analogues. Thus, Ingavirin Tamiflu, of Swiss origin, has a similar regimen of use, but the mechanism of action of the drugs is different. Drugs such as Arbidol, Imusstat are preventive and therapeutic for influenza and ARVI. Medicines are effective in treating even complex forms of diseases.

Another analogue of the drug is Kagocel. This drug is prescribed to adults and children over 6 years of age in the treatment of influenza, ARVI, herpes and urogenital chlamydia. It is also effective as a prophylactic agent. The drug Detoxopirol is prescribed for bronchitis, herpes, tonsillitis, and diseases of the upper respiratory tract.

Price of the drug in pharmacies

Check out the price of Ingavirin in 2018 and cheap analogues >>> The cost of Ingavirin in different pharmacies can vary significantly. This is due to the use of cheaper components in the drug and the pricing policy of the pharmacy chain. But the important thing is that the price difference between foreign and Russian analogues remains almost unchanged.

On the MedMoon.ru website, medications are classified both alphabetically and by effect on the body. We publish only the most current and new medications. Instructions for use of Ingavirin are regularly updated at the request of manufacturers.

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Source: http://www.medmoon.ru/medicina/ingavirin_instrukciya.html

Ingavirin (antiviral drug for influenza and ARVI) - instructions for use, analogues, reviews, price

Names, release forms and composition

The shell of 30 mg capsules consists of the following substances:

  • Azorubine;
  • Gelatin;
  • Black diamond dye;
  • Patented blue dye;
  • Crimson dye.

The shell of 90 mg capsules consists of the following substances:

Inside the 30 mg and 90 mg capsules there is powder and granules of white or off-white color. The 30 mg capsules are blue and the 90 mg capsules are red. Capsules 30 mg and 90 mg are available in packs of 7 pieces.

Ingavirin – photo

This photo shows the appearance of the Ingavirin package and capsule.

Therapeutic effect

  • Stimulation of the production of interferon by leukocytes;
  • Stimulation of the formation of cytotoxic lymphocytes;
  • Increase in the number of NK cells;
  • Suppression of the production of pro-inflammatory biologically active substances (tumor necrosis factor, interleukins 1 and 6, etc.).

Stimulation of interferon production causes activation of parts of the immune system that destroy viruses and cells affected by them. Cytotoxic lymphocytes and NK cells destroy cells affected by viruses and, accordingly, an increase in their number leads to more effective and rapid elimination of pathogenic microorganisms. Suppression of the production of pro-inflammatory biologically active substances leads to the cessation of disease progression and indirectly promotes recovery.

  • Shortening the period of fever;
  • Reducing the severity of intoxication symptoms (headache, weakness, fatigue, etc.);
  • Reducing the severity of catarrhal symptoms (runny nose, sore throat, etc.);
  • Accelerating recovery and reducing the duration of the disease;
  • Reducing the risk and incidence of complications of viral infections.

Ingavirin does not have mutagenic (does not provoke mutations in genes), immunotoxic (suppresses the activity of the immune system), allergenic, carcinogenic, embryotoxic and irritant effects. Ingavirin also does not affect the ability to conceive and bear children.

The mechanism of antiviral action of Ingavirin - video

Is Ingavirin an antibiotic or not?

Indications for use

  • Treatment and prevention of influenza types A and B (including A/H1N1, A/H3N2 and A/H5N1);
  • Treatment and prevention of acute respiratory viral infections, such as adenovirus, rhinovirus and respiratory syncytial infections, parainfluenza.

Instructions for use

How to take Ingavirin

special instructions

Impact on the ability to operate machinery

Overdose

Interaction with other drugs

Use during pregnancy and lactation

Ingavirin for children

Ingavirin and alcohol

Side effects

Contraindications for use

  • Individual intolerance or allergic reactions to any components of the drug (including lactose intolerance, glucose-galactose malabsorption, etc.);
  • Pregnancy period;
  • Breastfeeding period;
  • Concomitant use of other antiviral drugs;
  • Age under 18 years.

Analogs

  • Amizon tablets;
  • Amiksin tablets;
  • Arbidol capsules and tablets;
  • Arbidol Maximum capsules;
  • Hyporamine sublingual tablets and lyophilisate for the preparation of a solution for inhalation or intranasal administration;
  • Isoprinosine tablets;
  • Kagocel tablets;
  • Lavomax tablets;
  • Oksolin nasal ointment;
  • ORVItol NP capsules;
  • Panavir injection solution, rectal and vaginal suppositories;
  • Tilaxin tablets;
  • Tiloron capsules;
  • Triazavirin capsules;
  • Ergoferon lozenges and oral solution.

Cheap analogues of Ingavirin

  • Amizon – 195 – 254 rubles;
  • Arbidol – 150 – 250 rubles;
  • Hyporamine – 120 – 160 rubles;
  • Kagocel – 210 – 240 rubles;
  • Oksolin 20 – 60 rubles;
  • Ergoferon – 250 – 390 rubles.

Ingavirin - reviews

Advantages of Ingavirin in the treatment of influenza and ARVI - video

What is better than Ingavirin?

Kagocel or Ingavirin?

Ingavirin or Arbidol?

Drug price

Author: Nasedkina A.K. Specialist in research of biomedical problems.

Read more:
Reviews

After this incident, as soon as I feel like I’m getting sick, I immediately run to the pharmacy for Ingavirin, especially since the price is quite affordable - almost all advertised anti-virus remedies cost at least 800 rubles, and this one is half that price. Once I was faced with its complete absence in pharmacies - it was winter and the flu epidemic was in full swing, I had to buy another antiviral, but the effect was not at all the same. That’s why I usually have a couple of packs of Ingavirin at home, just in case, so to speak.

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