Acyclovir ointment

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Acyclovir ointment - composition, use, features and contraindications

Acyclovir ointment is a drug with antiviral activity, intended for external use only. The instructions for use of this medicine indicate that it can be prescribed for the treatment of certain types of viral diseases with manifestations on the skin and in children.

Table of contents:

Acyclovir acry ointment is similar in composition; several more subtypes of this ointment can be purchased in pharmacies - the additional prefix to the main name indicates only the manufacturer of the drug.

Composition and pharmacological properties of Acyclovir ointment

The main active ingredient of the ointment is acyclovir, which belongs to the group of synthetic analogues of deoxyguanidine . This substance is a component of DNA. Acyclovir is active against herpes simplex viruses type 1 and 2, which cause not only herpes, but also herpes zoster and chickenpox. The ointment exhibits moderate activity when exposed to Epstein-Barr viruses and cytomegaloviruses.

After application to the skin, acyclovir ointment penetrates directly into cells infected with a microorganism, that is, a virus. In cells, acyclovir interacts with viral enzymes, disrupts their normal development and thus breaks the chain of reproduction of pathogenic microorganisms. The drug has no effect on healthy cells.

When applied to intact skin, the ointment is practically not absorbed. When treating damaged skin, the components of the drug penetrate into the general bloodstream in small quantities, but are quickly excreted by the kidneys.

Acyclovir for external use is available in three different forms: 5% ointment and 5% cream , and three percent ointment intended for the treatment of ophthalmic diseases. In addition to stopping the virus from multiplying when applying any of the following products to the skin:

  • Pain sensitivity decreases.
  • The likelihood of further spread of rashes throughout the body is reduced.
  • The risk of complications is reduced.
  • The formation of a crust is accelerated.

The use of Acyclovir allows you to minimize recovery time, and reviews from people who use this ointment have repeatedly confirmed this fact.

Indications for use

Traditionally, the drug is used against herpes, but the scope of its use is much wider. The instructions for use of Acyclovir ointment indicate that it can be prescribed for the treatment of:

  • Herpetic eruptions at the second or third stage of their development.
  • Herpetic keratitis.
  • Shingles and chickenpox.

The use of acyclovir ointment for herpes helps prevent further spread of blisters. The drug is effective not only in the development of herpetic rashes on the skin, it is also prescribed for treating the mucous membranes of the external genitalia. The ointment can be used in the treatment of herpetic stomatitis.

It is best to start applying the medicine at the earliest stage of an exacerbation of herpes. Only in this case the manufacturer guarantees the highest therapeutic effect. The drug is also effective in exacerbating herpes infections that occur after chemotherapy, in the postoperative period, and in HIV-infected patients.

Is it possible to apply acyclovir to the eyelids and mucous membranes of the eyes? To treat the eyelids, you can use regular 5% ointment. But if treatment of the inner eyelid is required, then a special eye ointment containing only 3% acyclovir .

Acyclovir acri ointment is used in the same cases as the regular drug. Both drugs have the same properties and mechanism of action on the virus.

Contraindications for use

Acyclovir in the form of an ointment is not prescribed if the body's sensitivity to the main component of the drug or to the auxiliary ingredients is increased. No extensive clinical trials have been conducted during pregnancy and lactation. Therefore, Acyclovir ointment during pregnancy and throughout breastfeeding should be prescribed strictly by a doctor.

Features of treatment with Acyclovir ointment

In order for the drug to bring maximum benefit and not lead to the development of side effects, you need to know how to apply Acyclovir, how much to use and the frequency of application per day. Basic rules for using Acyclovir ointment:

  • Before applying the ointment, it is necessary to remove all cosmetics and other medications from the site of the rash.
  • The ointment is applied only with a glove or with one finger in a fingertip. This is necessary to prevent the herpes virus from entering healthy areas of the skin.
  • Apply the drug from the periphery to the center. The layer of medicine should be thin, but dense enough and covering the entire area of ​​the rash.
  • The frequency of use of the ointment per day is 5-6 times, the interval between applications should be at least 4 hours. When treating elderly patients, Acyclovir is prescribed with a frequency of application no more than three times per day.
  • After distributing the drug, it is necessary to avoid exposure to water for at least an hour and a half.
  • Treatment must be continued until the resulting rash dries. But the course of therapy should not be less than five days, even if all the rashes have disappeared. And the duration of treatment should not exceed 10 days. If the symptoms of herpes do not disappear during this time, you should consult a doctor.

When a child develops chickenpox, Acyclovir ointment is used only if the disease occurs with a high fever and a large number of blisters on the body. In addition to the external use of the medicine, the doctor may prescribe such children treatment with systemic antiviral agents and the use of antipyretics if necessary.

Acyclovir for chickenpox in the form of an ointment is most often prescribed to adults. This infection in adult patients is usually more severe, and the use of ointment reduces pain and prevents further formation of rashes on the skin.

Important! It must be remembered that applying Acyclovir to the skin does not prevent transmission of infection to other people. Therefore, during the period of exacerbation of herpes infection, contact with other people should be limited.

Acyclovir eye ointment, that is, a 3% drug, is prescribed for the treatment of herpes keratitis and other viral diseases of the mucous membranes of the eye.

Its application has its own characteristics:

  • Русский
  • The ointment must be placed behind the conjunctival sac.
  • The medicine is used no more than five times a day, and the general course of therapy is no more than three days. Compliance with this rule reduces the side effects of Acyclovir.
  • Contact lenses are avoided throughout the treatment.

It must be remembered that for some diseases, applying only antiviral ointment is not enough. An ophthalmologist may also see the need to use eye drops with a specific mechanism of action.

What to consider when using Acyclovir

It is advisable for patients with herpes to always keep Acyclovir ointment on hand. This will allow you to start using it immediately after the first signs of an exacerbation of the virus appear - burning and soreness. As practice shows, only earlier application of the ointment can avoid the formation of a large number of painful rashes. The ointment should be prescribed to children only according to indications; it should not be used for mild cases of chickenpox.

When using Acyclovir as a topical treatment for genital herpes, you must remember that this drug will not protect your sexual partner. Therefore, for the entire period of the rash, sexual contact should be prohibited.

The therapeutic effect of Acyclovir is also determined by the state of the immune system. In case of severe immunodeficiency, it is necessary to use not only external, but systemic antiviral agents, as well as immunomodulators.

What to choose: acyclovir cream or ointment?

These two dosage forms have the same content of the main active ingredient - 5% acyclovir . They differ in texture. The ointment contains more fat base, so it is denser and therefore acts longer and better. The texture of the cream is light and is usually recommended for use when treating the mucous membranes of the genital organs and the inside of the lips for herpetic rashes.

When applying the ointment, pain and burning may increase. Some patients experience allergic reactions in the form of swelling, redness, and small rashes. If these changes are detected, the ointment is washed off the skin, and further treatment should be prescribed by a doctor.

Be sure to store the ointment correctly. An unopened tube is stored in a cool place for 2 years from the date of release. An opened tube should be used within a year, after which it should be disposed of.

Cost of Acyclovir and drugs with similar effects

The price for the domestic drug is the most affordable - a small tube of medicine costs starting from 15 rubles. Acyclovir Sandoz ointment, produced in Germany, is distinguished by its high cost. Its cost starts from 150 rubles, although in terms of composition and mechanism of action it does not differ much from the Russian drug.

The most famous and frequently prescribed analogues of Acyclovir ointment based on the active ingredient:

  • Русский
  • Zovirax
  • Cyclovir
  • Vivorax
  • Virolex
  • Herpesin
  • Lisavir
  • Provirsan
  • Medovir

Herpes infection is a disease that cannot be completely defeated. To reduce the likelihood of another exacerbation, you should contact a qualified doctor who will prescribe treatment based on the diagnosis. And Acyclovir can be included in this treatment regimen not only in the form of an ointment, but also in the form of tablets.

Reviews

“Acyclovir is an excellent ointment for herpes on the lips. But with one caveat - it must be applied almost immediately after the itching and initial redness appear. If this moment is missed, then you can expect the appearance of large and very painful rashes.”

“I have a recurrence of genital herpes almost every spring and autumn. During this period, I take the medications prescribed by the doctor and at the same time apply Acyclovir cream, it is well absorbed and significantly reduces discomfort.”

All information is provided for informational purposes. And it is not an instruction for self-treatment. If you feel unwell, consult a doctor.

Source: http://vse-mazi.ru/acziklovir_maz.html

What does Acyclovir help with: herpes, stomatitis, vision?

Why and what does Acyclovir ointment help with? Instructions for use of the drug, indications and contraindications for its use, detailed description of the composition and analogues of the drug.

The material also contains patient reviews and their criticisms. The information will be useful to everyone who has used or is planning to use this tool.

Description

What is this remedy used for? Acyclovir ointment is a very effective antiviral drug that acts selectively on the herpes virus, stopping its development.

As you know, herpes affects the skin and mucous membranes of humans, so the drug is available in the form of an ointment, predominantly pale yellow in color. External use only.

Two types of ointment are available, which are divided depending on the concentration of the active substance - acyclovir itself.

  1. 5% - used for external use on more resistant skin and mucous membranes.
  2. 3% - for treating the mucous membranes of the eyes.

It is worth noting that the ointment does not help with acne that is of bacteriological origin.

The most common form of release of Acyclovir is ointment, but it also comes in the form of cream, tablets and injection solution, but in this form it is used much less frequently.

Compound

As mentioned above, the main active ingredient is acyclovir. In a classic ointment, its amount should be at least 5%. The primary excipients include:

These substances are also present in the eye ointment, but due to the specific application, the amount of acyclovir there does not exceed 3%.

Indications for use

Acyclovir is great for treating herpes, but its field of application is much wider. Due to the specific composition and action, it is also used in the following cases:

  • herpes in the first and second stages - use prevents the spread of the rash, reduces the risk of complications, accelerates the healing of affected areas. It works equally effectively both when a rash appears on the skin and when herpes appears on the mucous membranes, for example, on the lips. The drug is used for herpes stomatitis;
  • herpetic kerotitis - inflammation of the cornea of ​​the eye, in this case 3% acyclovir ointment is used;
  • chickenpox and shingles - in the case of chickenpox in adults, it is recommended to treat acne with acyclovir to make the disease easier;
  • the appearance of herpes due to immunodeficiency caused by HIV, severe surgery or chemotherapy;
  • barley - the effectiveness in this case will be quite limited, since this disease is of a bacteriological nature, and the profile of acyclovir is viral diseases. But the ointment contains an antibiotic, which makes it possible to treat barley.

Contraindications

The drug has a number of contraindications, which are caused by the specifics of its action and the characteristics of its composition. Most often, problems arise in people with individual intolerance to its components.

If Acyclovir ointment is used incorrectly, the following undesirable effects may occur:

  1. Discomfort and pain at the site of application of the ointment.
  2. The appearance of rashes and itching, allergic reactions in the form of urticaria.
  3. In women, inflammation of the external genital organs (vulvitis).

If you experience one or more of the symptoms listed above, you should immediately stop using the drug and seek help from a doctor. As a rule, after stopping the procedures, the symptoms quickly disappear, but this does not happen in all cases. Sometimes additional help and treatment may be needed.

Disputes continue over whether the ointment can be used during pregnancy and lactation. To date, relevant research is being carried out, but the question remains open.

Instructions for use

How to take Acyclovir ointment correctly? To avoid complications and make treatment as effective and quick as possible, you must adhere to the following instructions:

  • apply the ointment using medical gloves or special finger caps to avoid getting the ointment on healthy areas of the body;
  • The minimum interval between repeated applications should be at least 4 hours. Their maximum number should be no more than 5-6 times a day. For elderly people and patients with renal failure, this figure is no more than 2-3 times per 24 hours;
  • treatment continues until the herpes rash dries, which usually occurs 5 to 10 days after the start of the procedures. If the drug has not given positive results during this time, you should consult a doctor;
  • to avoid washing off the ointment, do not shower for 1.5-2 hours after applying it;
  • Only the affected areas should be smeared, and the amount of the drug should cover the entire painful area with a thin but dense layer.

► Acyclovir does not prevent people who come into contact with you from becoming infected. When in their company, remember this!

In the case of chickenpox in childhood, you should not use the drug, since the disease in children is milder than in adults.

Separately, it is worth talking about the use of 3% Acyclovir ointment for diseases of the mucous membrane of the organs of vision.

  1. The drug is used no more than 5 times a day for three days. This course of treatment is the safest for the patient’s eyes.
  2. The ointment is usually applied by placing it behind the conjunctival sac.
  3. It is not recommended to wear contact lenses during eye treatment.
  4. For herpes kerotitis, Acyclovir alone may not be enough, so additional remedies are often used (Zorax drops, for example), but only after consulting a doctor.

Analogs

Drugs that are closest in action to acyclovir include:

It is worth noting that each of them uses the same acyclovir as the main active element. The drugs differ in price, with Acyclovir being one of the cheapest drugs in this group, the most expensive drug being Zovirax.

Video: Acyclovir - choice of form and tolerability of the drug, consequences.

Reviews

I always have Acyclovir ointment in the refrigerator and when signs of a cold appear on my lips, this medicine helps perfectly. As a rule, the blisters disappear within 2-3 days after starting use. In addition, it can be used to smear pimples with chicken pox. A small tube of five grams lasts a very long time. I bought it a long time ago, so I can’t say the exact price, but I know that it’s cheap.

I very often come across a cold on my lip, I used to suffer very much from it and didn’t know how to treat it, but recently the pharmacy recommended Acyclovir to me. It's inexpensive and at first I thought it wouldn't help. This ointment should be taken at the first signs of the disease, and as soon as redness and itching appeared, I immediately applied it, and it helped me. It was not always possible to apply it as written in the instructions, but the drug helped anyway. I recommend him to everyone!

For me, the herpes virus is a real nightmare. It is almost impossible to get rid of it, unless you constantly strengthen your immune system so that the rash does not appear so often. All folk recipes did not help me, and I consider them useless. The only option to more or less quickly eliminate herpes is to anoint it with Acyclovir or a drug based on it. After 2-3 days, the pimples begin to dry out, and the pain disappears immediately. The price is very affordable, so I recommend it to everyone.

Additional questions

► Can I use it during pregnancy?

Use during pregnancy is not advisable, since animal tests have shown that elements of Acyclovir can cross the placenta. However, doctors' opinions differ. Some believe that the drug can be used when a viral infection of the mother poses a greater danger to the child than the use of the medicine itself. In any case, visit your doctor first.

► While breastfeeding?

During lactation, the use of Acyclovir is also not recommended, since its elements tend to penetrate into mother's milk and can harm the baby. But if the doctor believes that the use is necessary, he can still prescribe it.

► Acyclovir – cream or ointment: which is better?

The use of cream or ointment depends on the areas where the rash appears. If it occurs on the lips or face, then it is better to use ointment; it lasts longer and will help avoid injury to problem areas. If herpes appears on the body at the point of contact with clothing, then you can use a cream that is absorbed faster and does not leave stains.

The shelf life of Acyclovir is 3 years. It should be stored out of the reach of children, at a temperature of +15 to +25 Celsius. It is worth noting that after opening the tube, the manufacturer recommends using the ointment for a month.

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Once in the hospital I was infected with the herpes virus during a nose operation, as a result of which my entire face was covered with watery sores, right down to my ears. A lot of time has passed, and herpes periodically appears on the lip. I save myself with Acyclovir or burn it with toothpaste. To be honest, this is the first time I’ve heard that barley can be treated. My sister suffers from this disease; once she even had to cut her eye. But I still wouldn’t risk applying this product to the mucous membrane; I think there is something softer.

And purely out of intuition, I applied Acyclovir to the chicken pox pimples. They went by much faster. It turns out that the ointment can really be used for this disease.

Colds on the lips appear periodically. To get rid of it I always use acyclovir. It turns out that the ointment is so universal and can be used for barley and chickenpox. Thank you for the article.

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possible if a link to the source is required.

The resource materials are intended for informational purposes only,

they are not a substitute for qualified medical care.

Source: http://infozuby.ru/ot-chego-pomogaet-aciklovir.html

Acyclovir ointment - instructions, features of use, price

It is difficult to find a person who has never encountered a viral disease called herpes. Most often, people notice groups of crowded blisters in the mouth area. In this case, most people use ointment for herpes on the lips. One of the most common such products is Acyclovir ointment.

Despite the fact that this remedy is known specifically for use against the herpes virus, in fact the medicine also works for a number of other diseases. Moreover, there is Acyclovir eye ointment, which is actively used in the ophthalmological field. You can buy the drug at any pharmacy at a very affordable price.

Acyclovir ointment is an effective and affordable remedy for combating infectious diseases, including herpes

Description and composition

Acyclovir is an effective antiviral agent that selectively affects the herpes virus. There are various forms of release of this medicine, but among the external options two are used:

  • Acyclovir ointment 5%. This option is most often purchased to combat herpes in the mouth area, as well as on other areas of the skin and mucous membranes.
  • Acyclovir 3%. This type is often prescribed by ophthalmologists when treatment of the mucous membranes of the eyes is required.

The active component of the composition is a substance with the same name - acyclovir. Auxiliary elements vary depending on the specific brand of the drug. For example, the composition of Acyclovir Acri ointment includes propylene glycol, petroleum jelly, medical petroleum jelly, an emulsifier and polyethylene oxide.

Other variants of the drug are also common, such as Akrikhin ointment, Acyclovir Sandoz and others. They usually contain auxiliary components such as nipagin, purified water, nipazole and refined chicken fat. Regardless of whether you purchase an ointment or a cream that helps against the same herpes, the composition will be approximately the same.

The ointment is packaged in aluminum tubes in an amount of twenty grams. They are placed in cardboard packages. In addition to the medicine itself, the package includes Acyclovir ointment instructions, which describe in detail how this product should be used. The substance has a white-yellowish tint without a distinct odor.

The ointment is produced in a convenient tube for use and storage; it is better to always have such a product in your home medicine cabinet

Indications for use

Ointment for external use Acyclovir is effective against various types of herpes. The most common of them are considered to be viruses of the first and second types. The first is the so-called herpes simplex, which is why “cold” blisters appear on the lips. Due to exposure to the second type, genital herpes develops, that is, symptoms will be observed in the genital area.

The group of herpes viruses includes the varicella zoster virus. This third type causes two common diseases - chickenpox and shingles. The fourth type is the Epstein-Bar virus. Most often, it causes infectious mononucleosis in people. The fifth type is cytomegalovirus, which causes cytomegalovirus infection.

In total, science knows eight types of herpesvirus, but the features of the sixth, seventh and eighth still remain unknown. According to some assumptions, they may be associated with the appearance of roseola infantile and chronic fatigue syndrome.

What does Acyclovir ointment help with:

  • Herpetic lesions in the first or second stage,
  • Herpes stomatitis,
  • Herpetic keratitis,
  • Chicken pox,
  • Shingles.

The drug is prescribed to people infected with HIV, as well as to those who have recently undergone major surgery or chemotherapy. Due to problems with immunity, they are especially likely to develop herpes. What else you can use the ointment for is to eliminate barley, but this is only due to the presence of an antibiotic in the composition.

Acyclovir ointment is also used to reduce rash symptoms in adults and children with chickenpox

Contraindications and side effects

You will have to select analogues for use in case of intolerance to any substance from the composition. In general, the drug is considered to be well tolerated by the body. Any negative consequences occur very rarely. However, the instructions for using Acyclovir ointment note the existence of proven side effects, such as:

Most often, this occurs when a person does not follow the indicated dosages correctly. It is important not only to use the required amount of cold medicine, but also not to exceed the recommended duration of treatment. Otherwise, pain and discomfort in the treated area may occur.

Note . Sometimes the negative consequences of therapy can only be eliminated with medical help.

When the gel is used to treat genital herpes, it can lead to inflammation in the female genital area. If you find vulvitis, hives, itching, rash or any other unpleasant symptom, you need to consult a doctor. In most cases, side effects disappear after stopping use of the medicine, but this does not always happen.

If you experience any side effects from Acyclovir ointment, you should stop using it and consult your doctor.

How to use the ointment?

Doctors recommend applying the product using medical gloves or special finger pads. In this case, the components will not get on healthy skin, where their effect is not required. The specific amount of ointment used is determined only by the doctor.

There should be at least four hours between each re-application. You should not treat your skin more than six times a day. If a herpetic lesion occurs in an elderly person, then it is necessary to further reduce the dosage. It is permissible to use the medicine only two or three times during the day.

The moment of cessation of therapy is determined by the drying of the bubbles. Most often, this occurs after a week of treatment, but the time period is five to ten days. If no positive changes are observed within such a period, you need to consult a doctor and choose some analogues.

Unfortunately, modern pathogens are highly resistant to the drug. More than fifty percent of patients who suffer from recurrent herpes develop insensitivity to the active component of the composition. To increase effectiveness, doctors sometimes recommend combining tablets and Acyclovir ointment.

You must follow the instructions when using the ointment and take the necessary precautions

Features of application

For an adequate therapeutic effect, you do not need to wash off the product for at least two hours after application, and therefore you should avoid going to the shower during this time period. It is very important to treat exclusively the affected areas, and this should be done in a thin, dense layer.

As prescribed by an ophthalmologist, Acyclovir ointment for eyes is used as follows:

  • The product is placed behind the conjunctival sac.
  • The maximum number of possible repeated applications per day is five times.
  • Three days of treatment is usually sufficient.
  • During the course you will need to avoid wearing contact lenses.

Parents should discuss with their pediatrician whether Acyclovir can be used for children. The drug is not purchased for children under three years of age, and it is also not suitable for newborns. Moreover, children do not need Acyclovir ointment to treat chickenpox if they are between two and twelve years of age. At this time, the disease is mild, and additional drug therapy is not needed.

Note. The use of Acyclovir Akrikhin ointment is similar to other options.

The dosage for children is calculated based on their weight. Typically, no more than 0.25 g of product is applied for every 25 cm2 of skin. Although the medicine is practically not absorbed into the child’s bloodstream, babies may experience negative reactions in the form of diarrhea, nausea, vomiting and fever. It is necessary to discuss the permissible amount of medication with your pediatrician.

Only your pediatrician can prescribe this ointment to your child, no need to self-medicate

Acyclovir during pregnancy

During the first trimester of pregnancy, the use of acyclovir-based medications is prohibited. The second trimester is also sometimes included in the list of contraindications. You should consult your doctor about whether antiviral therapy can be carried out during such a difficult period. Pregnant women are never prescribed Acyclovir tablets, and the external form is sometimes allowed at later stages.

Since there are still no full-fledged studies on the effect of the drug on the gestation period, if possible it is worth abandoning such antiviral therapy. However, if the doctor decides that it is better to cure herpes, then Acyclovir ointment will be prescribed during pregnancy.

Don't worry about how much Acyclovir ointment costs. The price of the drug is rubles, you can buy it in almost any pharmacy. Among the well-known analogues are drugs like Famvir, Valtovir, Immunofan, Virolex, Vivorax and Herperax.

It is important to remember that you should not take acyclovir-based drugs during the first trimester of pregnancy

Source: http://simptom-lechenie.ru/instrukciya-po-primeneniyu-mazi-aciklovir-osobennosti-ispolzovaniya-cena-sredstva.html

Acyclovir – cream, ointment

keratomas on the face, and after this hot summer everything went wrong in the body. Treat

Cosmetologists don’t have the means. Can I try to use it myself?

glycifol ointment and how to evaluate the reaction? Thanks in advance. Alina

Take these drugs (Hilak-Forte and Biovestin) at different times, with an interval of about 6 hours. Simultaneously does not mean together.

Since the doctor didn’t tell you anything, do a control test 1-2 days after the end of treatment (and, preferably, an additional one six months later). You can begin sexual activity without a condom when tests on both you and your husband show the absence of infection (this means the first test, 2 days after the end of treatment)). However, everything is fine with my husband, congratulations.

The doctor prescribed me Gevisosh ointment (herpes prevention), but I can’t find it in any pharmacy. They say that there is no longer any supply of the drug. Can you tell me if there is an analogue of the drug? Thank you in advance.

Discuss with your doctor the possibility of using these drugs: acyclovir, penciclovir, valacyclovir (Valtrex), famciclovir (famvir).

The information provided is intended for medical and pharmaceutical professionals, should not be used for treatment and cannot be considered as official. The most accurate information about the drug is contained in the instructions supplied with the packaging by the manufacturer. No information posted on this or any other page of our website can serve as a substitute for personal contact with a specialist.

Please pay attention to the specified dates for entering information; information may become outdated.

Source: http://www.webapteka.ru/drugbase/name758_desc268.html

Acyclovir cream: instructions for use

Acyclovir cream is an antiviral agent for external use. It has a therapeutic effect for various herpes infections by blocking viral replication.

Release form and composition

Acyclovir cream for external use is available in 5 g tubes. The active ingredient of the drug is acyclovir, its concentration is 5% (1 g of ointment contains 5 mg of acyclovir). In addition to the active ingredient, the cream contains auxiliary components, which include:

  • Medical Vaseline oil.
  • Emulsifying type A cetostearyl alcohol.
  • Poloxamer 407.
  • Propylene glycol.
  • Dimethicone.
  • Purified water.

One cardboard pack of the drug contains 1 tube with 5 g of cream and instructions for its use. The concentration of the active substance is sufficient to block viral replication.

pharmachologic effect

The active substance of the drug acyclovir is an analogue of the nucleoside thymidine. Its mechanism of action is that after penetration into an infected cell, the viral enzyme thymidine kinase catalyzes the conversion of acyclovir into acyclovir triphosphate, which is integrated into the genetic material of the virus (DNA) and prevents the reading of information (transcription), which leads to blocking the transcription process (formation and assembly of new viral particles). In healthy cells not infected with the virus, the enzyme thymidine kinase is absent, so acyclovir is not converted into the triphosphate form and does not have a negative effect on the genetic material of the cell. The virus is most active against herpes viruses (Herpes simplex) and herpes zoster (Varicella zoster). The active substance of the drug has less effect on cytomegalovirus and Epstein-Barr virus.

When used externally, the active ingredient of the cream, Acyclovir, is well absorbed by the cells of the skin and mucous membranes in the area of ​​its application. Acyclovir is practically not absorbed into the systemic circulation.

Indications for use

Acyclovir cream is indicated for the treatment of skin manifestations of various herpetic infections, which include:

  • Herpes with skin rashes on the lips, genitals and other parts of the body.
  • Herpes zoster with the development of a characteristic rash on areas of the skin corresponding to the innervation of the nerve affected by the viral infection. After applying Acyclovir cream, the severity of the rash and the intensity of pain decrease.
  • Chickenpox is an infectious viral process with the appearance of a rash throughout the body in the form of small blisters filled with liquid.

It is not recommended to apply Acyclovir cream to the mucous membranes of the body.

Contraindications for use

The use of Acyclovir cream is contraindicated in the event of the development of individual intolerance to the main active ingredient of the drug or its auxiliary components. It is also not recommended to apply the cream in the presence of allergic reactions, which are mainly manifested by changes on the skin in the form of a rash, itching, or the development of a rash against the background of swelling of the skin, which resembles a nettle burn (urticaria).

Dosage and method of administration

Acyclovir cream is a medicine for external use. It is applied to the affected area of ​​the skin, which has elements of a rash indicating the presence of a herpes infection. It is also possible to apply the drug in the area of ​​​​herpes of the lips and genitals. The frequency of application of the cream is 5 times a day, with an interval of 4 hours between applications. The duration of treatment is on average 5 days. If during this time there is no improvement in the condition of the skin, a decrease in the intensity and severity of the rash, then the course of treatment can be extended to 10 days.

Side effects

Acyclovir cream is generally well tolerated, this is due to the lack of entry of the active substance into the systemic circulation. It is possible to develop allergic skin reactions after applying the cream to it, which manifest themselves in the form of erythema (redness of the skin), rash, itching or urticaria. In rare cases, it is possible to develop angioedema (angioedema) (severe swelling of the skin and subcutaneous tissue, with predominant localization in the face and genitals). If side effects develop, use of the drug must be discontinued.

special instructions

Before you start using Acyclovir cream, you must read the instructions for use, which are included in the cardboard box. It is important to pay attention to the following special instructions:

  • Acyclovir cream should not be used to treat herpetic eye infection (keratitis); for this purpose, there is a special dosage form of the drug - eye ointment.
  • If there is no effect of treatment, consultation with a dermatologist or infectious disease specialist is necessary to decide on the use of systemic antiviral drugs (taken in tablet form).
  • Acyclovir cream can be used by pregnant women and during breastfeeding, since the active substance of the drug is not absorbed into the systemic bloodstream.

In the pharmacy chain, Acyclovir cream is available without a prescription. If you have any questions or doubts, it is advisable to consult your doctor. During treatment of herpes of the lips, it is necessary to follow recommendations regarding the prevention of infection of healthy people with this infection (individual utensils and personal hygiene items).

Overdose

Due to the fact that the active substance of the drug is not absorbed into the systemic circulation, cases of overdose are unknown. Sometimes, with significant application to the skin, side effects may develop in the form of erythema and allergic reactions.

Analogs

Similar drugs that contain the same active ingredient are Acyclostad, Vivorax, Herpevir, Herperax, Zovirax.

Terms and conditions of storage

The shelf life of the drug from the moment of its manufacture is 2 years. After opening the package and using the ointment, its shelf life is 30 days. Acyclovir cream should be stored in a dark place, out of reach of children, at an air temperature of +15-25° C.

Acyclovir cream price

Acyclovir cream for local and external use 5%; aluminum tube 5 g - from 27 rub.

Source: http://bezboleznej.ru/aciklovir-krem

Antiviral ointment Acyclovir: instructions for use

Acyclovir is a drug that has an antiviral effect, mainly aimed at the herpes simplex virus and herpes zoster.

This ointment inhibits the DNA synthesis of the pathogen of the listed diseases. Suppresses the process of the appearance of new elements of herpetic eruptions, reduces the risk of complications, reduces pain in the acute period of the disease, and promotes faster formation of crusts.

On this page you will find all the information about Acyclovir: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Acyclovir ointment. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antiviral drug for local use.

Conditions for dispensing from pharmacies

Available without a prescription.

How much does Acyclovir cost in ointment form? The average price in pharmacies is 20 rubles.

Release form and composition

Two types of ointment are available, which are divided depending on the concentration of the active substance - acyclovir itself.

  • 5% - used for external use on more resistant skin and mucous membranes.
  • 3% - for treating the mucous membranes of the eyes.

The most common form of release is an ointment, but the drug comes in the form of cream, tablets and injection solution, but in this form it is used much less frequently.

Pharmacological effect

The main active ingredient of the ointment is acyclovir, which belongs to the group of synthetic analogues of deoxyguanidine . This substance is a component of DNA. Acyclovir is active against herpes simplex viruses type 1 and 2, which cause not only herpes, but also herpes zoster and chickenpox. The ointment exhibits moderate activity when exposed to Epstein-Barr viruses and cytomegaloviruses.

After application to the skin, acyclovir ointment penetrates directly into cells infected with a microorganism, that is, a virus. In cells, acyclovir interacts with viral enzymes, disrupts their normal development and thus breaks the chain of reproduction of pathogenic microorganisms. The drug has no effect on healthy cells.

Indications for use

The instructions for Acyclovir state that the ointment is effective against the following ailments:

  • chicken pox;
  • herpes zoster;
  • herpetic keratitis;
  • any infectious lesions of the skin caused by herpes Herpes Simplex types 1 and 2;
  • chronic and primary herpes on the mucous membranes of the lips and genitals;
  • damage by cytomegalovirus;
  • in case of damage to the skin of patients after surgery;
  • for the prevention of herpes damage to the skin and mucous membranes of patients with severe damage to the immune system due to chemotherapy or radiation therapy.

Contraindications

Acyclovir in the form of an ointment is not prescribed if the body's sensitivity to the main component of the drug or to the auxiliary ingredients is increased.

Use during pregnancy and lactation

The use of the drug during pregnancy is possible if the potential benefit to the mother outweighs the possible risk to the fetus.

The drug is found in breast milk after entering the mother's systemic circulation, so breastfeeding should be discontinued during treatment

Instructions for use

The instructions for use indicate that Acyclovir in the form of an ointment is used to treat herpes and lichen on the lip, in the intimate area, on the mucous membranes and on other skin areas.

Recommendations for use:

  1. Therapy should begin after noticing the initial symptoms - burning, itching, redness. If herpetic blisters have already appeared, it is important to avoid rupturing them so as not to spread the infection further during treatment.
  2. To prevent the spread of the virus, it is also necessary to use a cotton swab or gloves (all disposable) to apply the cream.
  3. The affected area and a small area around it (up to 5 mm) are covered with a thin layer of cream every 4 hours, with the exception of 8 hours of sleep at night.
  4. On average, the infectious process stops in 5 days, but with extensive inflammation, the course will need to be increased to 10 days.
Acyclovir eye ointment in the form of a strip 1 cm long is placed in the lower conjunctival sac 5 times a day (every 4 hours) until healing. Treatment is continued for another 3 days after healing.

Side effects

External use of ointment can cause the following side effects:

  1. Allergic reactions - urticaria, allergic dermatitis, blurred vision when putting the ointment into the conjunctival sac, swelling of the eyelids, keratopathy, blepharitis, conjunctivitis.
  2. On the part of the skin – itching, burning, soreness, redness, increased rash.

special instructions

Being one of the very first antiviral drugs, Acyclovir ointment brings the greatest effect in case of primary infection with the herpes virus when treatment is started in the early stages of the disease. About 60% of patients with a recurrent form of the disease suffer from reduced immunity, against which an infection has developed, so for the best effect, dermatologists prescribe immunostimulants and immunomodulators along with Acyclovir cream.

When applying the ointment into the conjunctival sac, a temporary deterioration in vision is possible, which can affect the ability to adequately drive vehicles and complex mechanical devices, therefore, after Acyclovir ointment gets into the eye, it is better to wait a while for the product to dissolve before driving a car. In addition, you need to look at the release date so as not to use an expired medicine.

Drug interactions

The simultaneous use of Acyclovir ointment with other oral antiviral drugs enhances the therapeutic effect of the ointment.

Simultaneous external use of ointment with Acyclovir tablets increases the risk of side effects if the dosage of the drug is incorrectly calculated.

Reviews

We have selected some people's reviews about the drug Acyclovir in ointment form:

  1. Masha. Herpes often bothers me, especially after or during colds. It appears mainly on the lips and on the nasal septum. I was looking for an effective ointment; the pharmacy offered me an inexpensive drug, acyclovir, which I used regularly, according to the instructions, treating the affected areas several times a day. But, unfortunately, I did not get the expected effect - with or without the ointment, the duration of the infection was the same.
  2. Svetlana . I have a recurrence of genital herpes almost every spring and autumn. During this period, I take medications prescribed by the doctor and at the same time apply Acyclovir cream, it is well absorbed and significantly reduces discomfort.
  3. Lana. Hi all! Previously, Herpes tormented me very often, as soon as I caught a cold, how about you... This thing pops up on my lip. But after, on the doctor’s recommendation, I started using Herpferon (which contains Acyclovir), now I get herpes no more than 1-2 times a year. Usually it’s autumn and spring, as soon as your lips get chapped - bam. Wait the next day - here it is. Or from nerves. It only comes out on the lower lip. It’s a good ointment and it helps quickly, 2-3 days and it’s all gone. I am very pleased, I advise anyone who has the same problems to try it! Now herpes is not a problem for me.
  4. Marina. Unfortunately, I have the herpes virus and periodically makes itself felt. I used to use Acyclovir cream, but it didn’t help much. Then I switched to an ointment in which the concentration of the drug was twice as high. The ointment effectively removes rashes and therefore is always in my purse. The good news is that the drug is harmless and can be used with virtually no restrictions. In addition, it increases local immunity, as a result of which I am protected for some time from repeated manifestations..

Analogs

The most famous and frequently prescribed analogues of Acyclovir ointment based on the active ingredient:

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25 °C. Shelf life: 3 years.

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One comment

Once in the hospital I was infected with the herpes virus during a nose operation, as a result of which my entire face was covered with watery sores, right down to my ears. A lot of time has passed, and herpes periodically appears on the lip. I save myself with Acyclovir or burn it with toothpaste. To be honest, this is the first time I’ve heard that barley can be treated. My sister suffers from this disease; once she even had to cut her eye. But I still wouldn’t risk applying this product to the mucous membrane; I think there is something softer.

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Source: http://simptomy-lechenie.net/maz-aciklovir/

ACYCLOVIR 5% 10.0 OINTMENT

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*PHARMACTIVES CAPITAL LLC*

Acyclovir instructions for use

Dosage form

Ointment for external use 5%

Compound

pharmachologic effect

Antiviral agent. Thymidine kinase in virus-infected cells actively converts acyclovir through a series of sequential reactions into acyclovir mono-, di- and triphosphate. The latter interacts with the viral DNA polymerase and is integrated into the DNA that is synthesized for new viruses. Thus, “defective” viral DNA is formed, which leads to suppression of the replication of new generations of viruses.

Pharmacokinetics

When taken orally, bioavailability is 15-30%. Widely distributed in tissues and body fluids. Plasma protein binding is 9-33%. Metabolized in the liver. T1/2 when taken orally - 3.3 hours, when administered intravenously - 2.5 hours. It is excreted in the urine, and in small quantities - in feces.

Side effects

When applied topically: burning sensation at the site of application, superficial punctate keratitis, blepharitis, conjunctivitis.

Selling Features

Available without a prescription

Special conditions

Use is not recommended for severe renal impairment.

Indications

as part of complex therapy for severe immunodeficiency (including the clinical picture of HIV infection) and in patients who have undergone bone marrow transplantation; prevention of cytomegalovirus infection after bone marrow transplantation.

Contraindications

Hypersensitivity to acyclovir and valacyclovir; with intravenous administration - lactation (breastfeeding).

Drug interactions

With simultaneous use, probenecid reduces the tubular secretion of acyclovir and thereby increases the plasma concentration and half-life of acyclovir.

  • You can buy Acyclovir 5% 10.0 ointment in Rossoshi at a pharmacy convenient for you by placing an order on Apteka.RU.
  • The price for Acyclovir 5% 10.0 ointment in Rossoshi is 36.00 rubles.

You can see the delivery points closest to you in Rossoshi here.

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Source: http://apteka.ru/rossosh/catalog/aciklovirmaz_85400/