Cromohexal instructions for use ophthalmic

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Cromohexal is an antihistamine for eye treatment.

Cromohexal eye drops are an effective antihistamine for the treatment and prevention of chronic and acute allergic eye diseases, including conjunctivitis and keratoconjunctivitis.

Table of contents:

The drug can also be used to relieve symptoms of dryness and irritation of the eyes, fatigue and eye strain.

Cromohexal fights eye irritation, has an anti-edematous effect, and eliminates allergic manifestations that occur when the mucous membrane is exposed to various contact allergens.

Instructions for use

Compound

One milliliter of Cromohexal eye drops contains the following substances:

  • 20 milligrams of sodium cromoglycate;
  • sodium chloride;
  • disodium edetate;
  • uncrystallized liquid sorbitol;
  • benzalkonium chloride;
  • sodium dihydrogen phosphate dihydrate;
  • disodium hydrogen phosphate dodecahydrate;
  • sodium hydroxide;
  • water for injections.

Indications for use

This drug is used for the prevention and treatment of chronic and acute allergic keratoconjunctivitis and conjunctivitis, which arise as a result of contact with allergens, such as plant pollen, pet hair, house dust, fungal spores, volatile compounds, etc. Cromohexal can also be used to prevent seasonal allergic reactions, including hay fever and hay fever.

You can also use Cromohexal to eliminate irritation of the mucous membrane of the eyes, which occurs as a result of contact with cosmetics, chlorinated water, smoke, and wind.

This drug is also used for dry eye syndrome, visual fatigue, and to eliminate eye redness and irritation caused by intense visual stress.

The article (link) contains all the reviews about Normax.

How to use?

Before you start taking the drug, you should consult your doctor. Cromohexal eye drops should be injected into the conjunctival sac. If the attending physician has not prescribed any other treatment, the drug is instilled into each eye, 1-2 drops, four times a day.

In case of significantly pronounced allergic manifestations, eye drops can be applied up to eight times a day. The duration of treatment with this method should be determined by the attending physician.

Once the therapeutic effect is achieved, the frequency of use of Cromohexal can be reduced and used only when in contact with allergens.

Contraindications

A contraindication to the use of Cromohexal is individual hypersensitivity to cromoglycic acid or any other component of this drug.

It is not recommended to use Cromohexal in patients under four years of age.

Although there is no data on the negative effect of Cromohexal on the fetus during pregnancy, this drug, especially in the first trimester, must be taken with great caution.

Since cromoglycic acid is excreted in small quantities in mother's milk, taking Cromohexal during breastfeeding is possible only if the benefit expected for the mother outweighs the likely risk for the child.

Side effects

Immediately after using the drug, short-term blurred vision or increased eye irritation may occur - swelling, burning, hyperemia of the conjunctiva, sensation of “sand” or a foreign body.

After a few minutes, these symptoms go away on their own. In very rare cases, inflammation of the meibomian glands of the eyelids (meibomitis), mild damage to the corneal epithelium, and the appearance of barley are noted.

Precautions and special instructions

Since Cromohexal contains the preservative benzalkonium chloride, it is necessary to avoid wearing soft contact lenses throughout the entire period of use of the drug.

If the patient uses hard lenses, they should be removed before instillation of Cromohexal and put on again after 15 minutes.

After each use of the drops, it is necessary to tightly close the bottle with a lid. To prevent microbial contamination, avoid contact of the dropper bottle spout with the skin, eyelashes or mucous membrane of the eye.

Once opened, the bottle can be used for six weeks.

If a day after starting to use this drug there is no reduction in the symptoms of inflammation, or these symptoms intensify, instillation of the drops should be stopped and consult a doctor.

With long-term use, regular monitoring of the state of kidney and liver function is required.

In Russian pharmacies, Kromohexal eye drops can be purchased at an average price of about 100 rubles. The average cost of this drug in Ukrainian pharmacies is 20 hryvnia.

Read on - the price of Sulfacyl Sodium. Reviews and instructions.

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Storage and release from pharmacies

The shelf life of Cromohexal drops is three years. They should be located out of the reach of children and protected from sunlight. The drug should be stored at a temperature no higher than 25 degrees Celsius, but drops should not be frozen. Once opened, the medicine must be used within six weeks.

Cromohexal can be purchased at any pharmacy without a prescription.

Analogs

Vividrin, Cromolyn, Ifiral, Sodium cromoglycate, Cromosol, Intal, Lecrolin, Cromalerg, Nalkrom, Hi-Krom, Allergo Chest, Cromoglin, Thaleum, Cromogen, Kuzikrom, Stadaglycin, Kropoz.

Reviews

Patients respond differently to Cromohexal eye drops. Some note the high effectiveness of this drug, while others claim that it did not help them get rid of allergy symptoms at all. Some patients noted that they quickly became addicted to Cromohexal, so they had to switch to another drug.

Persons suffering from bronchial obstruction or bronchial asthma noted that the use of Cromohexal provoked an increase in coughing attacks in them. From this we can conclude that the described drops are not suitable for all patients.

Before using them, you should consult your doctor. And if, during treatment with Cromohexal, the patient notices that his condition has begun to worsen, he should seek medical help so that the doctor can determine whether this is a reaction to Cromohexal and whether the patient’s condition precludes further use of the drug.

Examples

1. When my baby turned 1 year and 4 months old, I began to notice more and more often that he rubbed his eyes with his hands - well, he rubbed once, twice, or three. However, after a while it became so obvious that it was no longer necessary to think that an eyelash had gotten into the eye. And then it was time to visit the ophthalmologist.

At the appointment, when I complained that the baby was rubbing his eyes, the doctor pulled back the lower eyelid a little and discovered that the mucous membrane there was red, and not pink, as it should be.

In short, the doctor said that this was an allergic reaction, for the treatment of which he prescribed Cromohexal antiallergic drops for the eyes.

The drug is colorless, odorless, I even tasted it - slightly salty. The instructions indicate that side effects sometimes include itching and burning in the eyes.

However, even though the drops were prescribed to my child, and not to me, I first tested Cromohexal on myself. Perhaps, with severe inflammation and conjunctivitis, this drug burns, but my eyes did not react to these drops at all.

The child also allowed the drops in his eyes calmly and then did not cry, from which it was concluded that this drug also did not cause him any discomfort at all.

If we talk about effectiveness, Cromohexal really helped my baby - he stopped rubbing his eyes after just a few days.

2. I really regret that I didn’t find out about this remedy earlier. I started using these drops, and as a result I completely stopped taking allergy pills. And the cost is not that high - I bought a bottle of Cromohexal for 166 rubles. Previously, I had to buy more expensive drugs, but they ran out very quickly.

Conclusion

  • Cromohexal is an antihistamine ophthalmic drug;
  • It can be found in pharmacies in the form of eye drops;
  • It is also recommended to use Cromohexal to relieve eye fatigue;
  • This drug is not suitable for use in children under four years of age;
  • The use of Cromohexal may be accompanied by side effects;
  • If necessary, Cromohexal can be replaced with a similar drug.

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Cromohexal

Description current as of 08/10/2016

  • Latin name: CromoHEXAL
  • ATX code: S01GX01
  • Active ingredient: Cromoglicic acid
  • Manufacturer: Aeropharm GmbH, Dr. Gerhard Mann, Pharma Stulln (Germany)

Compound

Cromohexal nasal spray contains the active ingredient - cromoglicic acid, as well as additional components: disodium salt EDTA, sodium dihydrogen phosphate, sorbitol, benzalkonium chloride, sodium monohydrogen phosphate, sodium chloride, water.

Cromohexal eye drops contain the active ingredient - cromoglicic acid, as well as additional components: sodium chloride, disodium edetate, benzalkonium chloride, liquid sorbitol, disodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, water.

Cromohexal for inhalation in the form of a solution contains the active ingredient sodium cromoglycate and purified water as an additional component.

Release form

Several forms of this medicine are produced.

  • Cromohexal nasal spray 2% dosed is a colorless or yellowish solution that does not contain mechanical inclusions. Packaged in 15 ml or 30 ml polyethylene bottles, equipped with a dosing device.
  • Eye drops 2% - a transparent, yellowish solution that does not contain mechanical inclusions. Contained in 15 ml bottles.
  • The solution for inhalation is transparent, yellowish, and does not contain mechanical inclusions. Contained in polyethylene ampoules of 2 ml, which are placed in cardboard packs of 10 pieces.

pharmachologic effect

The medicine has an antiallergic effect.

All forms of Cromohexal include the active component disodium salt of cromoglycic acid. The active substance has a stabilizing effect on the membranes of basophilic granulocytes and also inhibits the entry of calcium ions into the cells. Since under the influence of the drug stabilization of mast cell membranes occurs, there is no degranulation and release of histamine, bradykinin and other mediators of allergy and inflammatory processes into the blood.

This remedy is most effective as a prevention of allergic manifestations. The clinical effect is observed after a few days of using the product.

Pharmacokinetics and pharmacodynamics

After the drug has been administered intranasally, less than 7.5% of the received dose is absorbed into the systemic circulation. 65% bound to plasma proteins. The half-life is 1.5 hours. The active component is eliminated after a day in urine and bile in approximately equal quantities. Metabolism does not occur in the body.

When using eye drops through the mucous membrane of the eye, the active component is absorbed slightly. The level of systemic bioavailability is less than 0.03%.

Indications for use

Cromohexal nasal spray is indicated for allergic rhinitis, which occurs seasonally or throughout the year.

Cromohexal eye drops are prescribed for both the prevention and treatment of keratoconjunctivitis, allergic conjunctivitis, allergic keratitis, as well as irritation of the eye mucosa associated with allergic reactions (the effect of environmental factors, cosmetics, household chemicals, pets, plants, etc.).

The inhalation solution is prescribed for the purpose of preventive treatment of manifestations of bronchial asthma of allergic and non-allergic origin, as well as for endogenous forms of asthma that are associated with stress, infection, and high stress.

Contraindications

Cromohexal in any form is contraindicated for use in case of hypersensitivity to any of the components of the drug.

Allergy eye drops and inhalation solution are not prescribed to children under 2 years of age, nasal spray - to children under 5 years of age. Also, the spray is not prescribed during pregnancy and breastfeeding.

With caution, Cromohexal spray is prescribed to people with liver or kidney failure, as well as to patients with polyps in the nasal cavity.

Side effects

Cromohexal nasal drops can cause the following negative effects:

  • respiratory system: burning or symptoms of irritation of the nasal mucosa, cough, sneezing, rhinorrhea, in rare cases - nosebleeds;
  • allergic manifestations: itching and rash, urticaria, swelling of the lips, face or eyelids, difficulty swallowing or breathing;
  • other manifestations: headaches, bad taste in the mouth.

The inhalation solution can cause the following unpleasant effects:

  • irritation of the trachea and pharynx;
  • a slight cough, in very rare cases - a reflex spasm of the bronchi;
  • skin rash;
  • inflammation of the gastrointestinal tract.

All phenomena are short-lived and disappear after discontinuation of the medication.

Eye drops can cause the following effects:

  • deterioration in vision clarity;
  • burning sensation in the eyes;
  • manifestation of lacrimation;
  • foreign body sensation;
  • swelling of the conjunctiva;
  • dry eyes;
  • meibomite (barley);
  • The lesion of the corneal epithelium is superficial.

Instructions for use of Cromohexal (Method and dosage)

Instructions for nasal spray

It is recommended to administer one dose of the drug into each nasal passage, that is, make one press, 4 times a day.

The maximum permissible dosage is 6 times a day, 1 dose. After the effect has been achieved, you can reduce the number of uses of the product per day. In this case, it is advisable to use a spray when in contact with allergens.

Treatment lasts for 4 weeks, drug withdrawal is carried out gradually over 1 week.

Before using the product, you need to remove the protective cap from the bottle and press the sprayer several times to achieve the optimal dosage. Before using the spray, be sure to thoroughly clean the nasal passages.

Instructions for Cromohexal for inhalation

It is recommended to carry out inhalations 4 times a day, for one inhalation use one bottle of 2 ml. If possible, equal time intervals should pass between inhalations. If necessary, you can increase the frequency of use of the product up to 6 times a day. After the therapeutic effect has been achieved, inhalations can be performed as needed.

When used regularly, Cromohexal solution prevents the manifestation of asthma symptoms, but it does not relieve acute asthma attacks. The course of treatment should be at least 4 weeks, the dose should be reduced gradually over one week. Special inhalers are used for inhalation.

Cromohexal eye drops, instructions for use

It is necessary to instill 1-2 drops of the product into each eye, this must be done 4 times a day. You can increase the number of procedures up to 6-8 times a day. After the therapeutic effect has been achieved, the product can only be used during contact with allergens. For chronic allergies, the duration of treatment is determined by the doctor individually.

Overdose

There is no information about an overdose of Cromohexal.

Interaction

When taken simultaneously, cromoglycic acid can enhance the effect of H1-histamine blockers.

Terms of sale

All forms of the product can be purchased without a prescription.

Storage conditions

All forms of Cromohexal should be stored at temperatures up to 25°C. Keep away from children. Vials of inhalation solution are intended for single use.

Best before date

All forms of medicine can be stored for 3 years; after the package with drops or spray has been opened, the product can be stored for 6 weeks. If stored incorrectly, the solution may turn yellow, in which case it should not be used.

special instructions

The product should not be used after the expiration date indicated on the drug packaging has expired.

If irritation or burning of the mucous membrane occurs, which does not disappear or intensifies, treatment should be stopped.

The inhalation solution should not be used to relieve acute asthma attacks.

When using any form of the drug for a long time, it is necessary to monitor the condition of the patient’s liver and kidneys.

When using Cromohexal eye drops, the need to take ophthalmic agents that contain glucocorticoids is reduced.

Due to the content of Cromohexal benzalkonium chloride drops, you should not wear contact lenses - remove them 15 minutes before instillation of the product and put them on no earlier than the same amount of time after.

The tip of the pipette must not touch the eye; the bottle must be closed after each use.

During treatment, you should be careful when performing activities that require concentration.

Analogs

The drug can be replaced only after prior approval by the attending physician.

For children

The spray cannot be used to treat children under 5 years of age; the solution and eye drops are not prescribed to children under 2 years of age. Cromohexal is used with caution in children under 4 years of age.

During pregnancy and lactation

Despite the fact that the use of Cromohexal for animals did not provoke a teratogenic effect, the drug is not prescribed for pregnant women. The active substance can pass into breast milk, so the medicine is not used during lactation.

Reviews of Cromohexal

Many reviews of the nasal spray, as well as reviews of eye drops, indicate that the drug provides effective prevention of allergy symptoms. A particularly pronounced effect from the use of Cromohexal is observed during seasonal exacerbations of allergies in people prone to such symptoms.

Many parents use the inhalation solution for children who suffer from bronchial asthma to prevent attacks. However, there are also reviews that after using Cromohexal, coughing attacks occurred more often in children. Therefore, it is important that only a specialist prescribes the medicine.

Cromohexal price, where to buy

The price of Kromohexal nasal spray is on average 150 rubles per pack. 15 ml. The price of Cromohexal for inhalation is from 380 rubles. for 50 ampoules. You can also buy Cromohexal eye drops without a prescription, the price of which is on average 100 rubles per 10 ml package.

  • Online pharmacies in Russia Russia
  • Online pharmacies in Ukraine Ukraine

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Education: Graduated from Rivne State Basic Medical College with a degree in Pharmacy. Graduated from Vinnitsa State Medical University named after. M.I. Pirogov and internship at his base.

Work experience: From 2003 to 2013 – worked as a pharmacist and manager of a pharmacy kiosk. She was awarded diplomas and decorations for many years of conscientious work. Articles on medical topics were published in local publications (newspapers) and on various Internet portals.

A very good product, I puffed twice and forgot))) the price is inexpensive compared to tafen, it helped me

Cromohexal nasal drops. A 5-year-old child was given drops at night, recommended by an allergist for seasonal allergies to flowers, as a result, they woke up with a barking cough, the child was choking, wheezing and wheezing, they called an ambulance, a dexamethasone injection, inhalation of pulmicort, Zyrtec drops, the ambulance team did all this. This is the medicine cromohexal

Tanya: I always use this remedy after a cold, because without it I can go a long time.

Zina: Export helped me with constipation. In addition, I developed dysbacteriosis. Fine .

German: prescribed by a proctologist. After a course (15 tablets), weeping appeared on the legs along the toes.

Ekaterina: Since childhood, when I worry, my stomach shrinks and becomes a lump, and then it hurts.

All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://medside.ru/kromogeksal

CROMOGEXAL eye drops INSTRUCTIONS

Cromoglicic acid acts directly on the membranes of mast cells, blocking the entry of calcium ions into these cells and the subsequent release of biologically active substances responsible for allergic reactions: histamine, bradykinins, leukotrienes, prostaglandins. Thus, cromoglycic acid inhibits the occurrence of immediate allergic reactions and prevents their occurrence.

The drug has a local decongestant effect, eliminates symptoms of eye irritation that occur when the eye mucosa is exposed to various contact allergens.

Cromohexal can be used for visual fatigue, dry eye syndrome, to eliminate irritation and redness of the eyes caused by exposure to intense visual stress.

The most pronounced therapeutic effect is usually observed within one to two days from the start of using the drug, therefore, to prevent seasonal allergies, it is necessary to start treatment in advance.

Cromohexal is used as a remedy for the treatment and prevention of acute and chronic allergic conjunctivitis and keratoconjunctivitis that occurs when exposed to various contact allergens, including house dust, pet hair, pollen, volatile compounds, etc. The drug can be used to prevent seasonal allergic diseases (hay fever, hay fever).

Cromohexal can be used to reduce symptoms of eye irritation and dryness caused by visual fatigue, irritation of the mucous membrane of the eyes caused by exposure to chlorinated water, smoke, cosmetics, wind and dust.

Cromohexal eye drops are intended for instillation into the conjunctival sac. Unless otherwise prescribed by the doctor, instill 1-2 drops into each eye every 4-6 hours (4 times a day). If allergic manifestations are significant, the frequency of instillation of the drug can be increased to 6–8 times a day. The duration of use of eye drops is determined by the attending physician.

Immediately after instillation of Cromohexal drops, a short-term deterioration in visual acuity may appear, as well as increased symptoms of eye irritation (feeling of a foreign body or “sand”, swelling, conjunctival hyperemia, burning). These symptoms go away on their own within a few minutes. In rare cases, meibomitis (inflammation of the meibomian glands of the eyelids), barley, and superficial lesions of the corneal epithelium may occur.

Cromohexal eye drops are contraindicated for use in case of individual hypersensitivity to cromoglicic acid or any other component of the drug. Contraindications to the use of drops are age under 4 years, as well as pregnancy and breastfeeding.

Cromohexal should be used with caution during pregnancy and lactation.

With the simultaneous use of Cromohexal drops with glucocorticosteroids, an increase in the effect of the latter is observed.

When used according to the instructions, an overdose of the drug Cromohexal was not observed.

Store in a dark place at a temperature of 20-25°C.

Shelf life is three years.

Cromohexal eye drops are available in plastic dropper bottles, the volume of each bottle is 10 ml.

1 ml of Cromohexal contains 20 mg of sodium cromoglycate.

Excipients: benzalkonium chloride, liquid sorbitol, EDTA, sodium chloride, sodium monohydrogen phosphate, sodium dihydrogen phosphate and water for injection.

Cromohexal contains benzalkonium chloride (a preservative), so the use of soft contact lenses should be avoided while using this drug. If the patient wears hard contact lenses, they should be removed before instillation and then reinserted 15 minutes after instillation.

The bottle should be tightly capped after each use of the drops. To prevent microbial contamination, do not touch the tip of the dropper bottle to the skin, eyelashes or mucous membrane of the eye. An open bottle can be used for 6 weeks.

If, within a day from the start of using Cromohexal, there is no reduction in the symptoms of eye irritation, or these symptoms intensify, you should stop instilling the drops and consult a doctor.

Reviews CROMOGEXAL eye drops

All reviews about CROMOGEXAL eye drops

Analogues of CROMOGEXAL eye drops

Reviews about medicine. Catalogue of medicines, pharmacies, hospitals, physicians base.

Source: http://www.medcentre.com.ua/medicamenty/kromogeksal-glaznye-kapli.html

Instructions for use of Cromohexal eye drops

Allergic diseases became widespread in the 20th century and became one of the most frequently diagnosed diseases by doctors. According to WHO forecasts, in the 21st century this disease will become one of the first places in terms of prevalence.

Among the manifestations of allergies, itching, watery eyes and redness of the mucous membranes of the eyes are as common as skin or nasal symptoms.

An effective remedy in the treatment of ophthalmic manifestations is Cromohexal eye drops. The drug has not only the ability to prevent and quickly suppress allergic manifestations, but also a fairly low price (about 100 rubles / 10 ml).

Mode of action and composition of Cromohexal eye drops

Cromoglycic acid is an effective remedy in the fight against ocular, nasal and bronchial allergic manifestations: rhinitis, cough, lacrimation, hyperemia of the eyelids and conjunctiva, nasal passages, itching and the sensation of a foreign object in the eye. It is used in many eye allergy medications, nasal drops and sprays.

Cromohexal contains eye drops of cromoglycic acid, which is the main active component of the drug - 2% (per 1 ml - 2 mg).

The effect of the drug is based on the ability of cromoglycic acid to penetrate the membranes of mast cells. It prevents calcium ions from entering mast cells, thereby blocking the release of proglastandins, leukotrienes and bradykinins, as well as histamine. And this, in turn, leads to a decrease in tear production, a decrease in swelling of the mucous membranes and redness of the skin around the eye; relieves inflammation, eliminates itching.

Excipients in the composition of the drug are: disodium edetate and saline solution, hydrogen phosphate dihydrate and sodium hydroxide, liquid sorbitol, distilled water, and a preservative (benzalkonium chloride).

Indications for use of Cromohexal drops

Eye drops eliminate symptoms of itching, inflammation and lacrimation caused by household dust, plant pollen, fungal spores, and animal hair. The drug is used in the acute period, as well as with prolonged manifestation of symptoms in complex treatment. The instructions for use recommend the use of Cromohexal for:

  • allergic conjunctivitis;
  • allergic keratoconjunctivitis;
  • hay fever (allergic rhinoconjunctivitis).

It is effective to use these eye drops as a prophylaxis during the flowering period of plants and other cases of possible occurrence of ophthalmic allergic reactions.

When treating dry eyes from smoke, strong wind, and volatile substances, the use of Cromohexal is also indicated.

The drug is recommended if there are symptoms of overwork and eye fatigue (working with documents, working at a computer monitor, etc.)

When should Cromohexal not be used?

Individual intolerance to cromoglycic acid will be among the contraindications listed in the instructions. Cromohexal is not prescribed if you are intolerant to other components of the drug.

Other reasons for not using this drug include:

  • Children under 2 years of age. Spray and solution for inhalation are used from 4 years of age.
  • To treat a child under 4 years of age, consultation with a pediatrician or pediatric ophthalmologist is required.
  • Pregnancy. The instructions do not indicate data that would indicate the safety of the drug for pregnant women, so their prescription should always be carried out by a doctor.
  • An absolute prohibition is the 1st trimester of pregnancy.
  • The lactation period (GL) is also considered a contraindication for use. In small doses, the drug passes into breast milk; its effect on the development of the child has not been studied.
  • Do not use the drug in the presence of corneal erosions.

Only 7% of the drug is absorbed by the eye structures, the rest is excreted by the kidneys and liver. The drug is prescribed with extreme caution to patients with renal or liver failure. Long-term treatment with Cromohexal will require constant monitoring of the functioning of these organs (urine and blood tests).

Instillation schemes and features of using Cromohexal

Cromohexal is available in pharmacies without a prescription, but it is advisable to discuss its use with your doctor. As a rule, in acute forms, the drug is instilled into the conjunctival sac, 1-2 drops in each eye after 6 hours. Elimination of symptoms occurs within an hour. Before use, the drops are heated to +20-22.

In the presence of severe lacrimation and hyperemia, the interval between instillations can be shortened to 3 hours. As the symptoms subside, it is increased to 6-7 hours.

When diagnosing seasonal manifestations, Cromohexal is instilled as a prophylactic agent 24 hours before the possible onset of symptoms, 1 drop every 6 hours.

Important. If after 24 hours the allergic symptoms have not disappeared or have intensified, the medication is discontinued and a doctor is consulted.

Interactions with other drugs and side effects of Cromohexal

Among the side effects of Cromohexal, the instructions for use list increased lacrimation, burning and blurred vision as the most common. Symptoms disappear spontaneously within a few minutes after the instillation procedure.

These symptoms after instillation require careful work that requires concentration and driving. Driving and work should be postponed and started no earlier than half an hour after instillation.

For patients using contact lenses, it is recommended to replace them with glasses during treatment. As a last resort, the lenses are put on 20 minutes after instillation. Cromohexal drops contain a preservative that damages lenses and the cornea by depositing on the inside of the lens.

Among the infrequent side symptoms with long-term (more than a month) use or non-compliance with instillation recommendations are:

  • inflammation of the meibomian glands (edges of the eyelids),
  • barley formation,
  • mild erosive lesions of the cornea.

Instructions for use indicate that simultaneous instillation of Cromohexal and taking a corticosteroid causes an increase in the effect of the latter.

Warnings when using the drug

Cromohexal will not have a therapeutic effect in the presence of viral or bacterial conjunctivitis, as well as in the case of fungal infections of the eye structures.

Allergic reactions weaken the immune system, which leads to the occurrence of secondary bacterial infections against the background of allergic manifestations. To avoid unwanted infection, you should adhere to the following instillation rules:

  • Before instillation, wash your hands with soap.
  • Carry out instillation in a clean room.
  • Close the bottle with drops tightly.
  • Do not touch the tip of the dropper to any surfaces, including the mucous membranes of the eye.
  • Use drops strictly individually.

Cromhexal should not be applied directly to the conjunctiva of the eye. They should be instilled into the conjunctival sac, onto the mucous membranes. This will help avoid acute burning and side effects.

Cromohexal eye drops can be stored for 6 weeks after opening the bottle. The drug is kept in a place inaccessible to direct sunlight, at a temperature not exceeding +25. Drops should not be frozen.

A hermetically sealed bottle can be stored for 3 years if the rules are followed.

Analogues of Cromohexal eye drops

In addition to eye drops, in pharmacies under the name Cromohexal you can find: a nasal spray in plastic bottles (15 or 30 ml) with a special spray cap and a solution for inhalation, available in ampoules of 2 ml. Blister tape contains 10 pcs.

There are many drugs based on cromoglicic acid to eliminate eye allergies. So the following drops will be absolute analogues of Cromohexal:

  • Cromicil - SOLOpharm. 10 ml/from 70 rub.
  • Lecrolin 20 ml /90 rub.
  • Cromoglin 20 ml / from 150 rub.
  • Nalcrom 20 ml/from 120 rub.
  • Optiwell 10 ml/ from 105 rub.
  • Sodium cromoglycate (powder for dilution) 90.

Other drugs for the treatment of allergic ophthalmic manifestations will be: Opatanol (active ingredient olopatadine), Allergodil (based on azelastine), Visine (alpha-adrenergic agonist).

For prolonged allergic manifestations that are not relieved by allergy drops, medications containing corticosteroids (Dexamethasone) are prescribed.

The content of all content presented on the site is for educational and informational purposes only, aimed at giving visitors to the resource a clearer idea of ​​healthy vision, its acquisition and maintenance, diagnosis, prevention and treatment methods and techniques.

Source: http://moeoko.ru/lechenie/kromogeksal.html

Instructions for use of eye drops called Cromohexal

Cromohexal is an antihistamine, available in the form of eye drops and nasal spray. The active component of the drug is disodium salt, isolated from cromoglycic acid. This is an antiallergic drug that effectively eliminates the main symptoms of allergies in the eye area. The medicine is available in 10 ml bottles.

Action of drops

Disodium salt has a stabilizing effect on the membrane elements of basophilic granulocytes. Thanks to the action of this component, the entry of calcium ions into cells is inhibited. Due to the stabilization of membranes, the product helps prevent the release of allergy and inflammatory mediators in the blood, such as histamine, bradykinin, and so on. The drug also prevents degranulation.

After introducing drops into the area of ​​the conjunctival mucosa, only 0.03% of the administered dose enters the systemic circulation. Binds to blood plasma by 65%. The drug is excreted in bile and urine within 24 hours. Metabolites are not released during excretion.

Cromohexal eye drops

Cromohexal in the form of eye drops is used for acute or chronic conjunctivitis with atopic origin - that is, with an allergic manifestation of the pathology during hay fever or seasonal type.

The use of the drug should continue after the symptoms disappear.

Studies regarding the effect of the drug during pregnancy were conducted only on animals. No teratogenic effect was detected. But this does not mean that the drug is safe for use by pregnant women, since adequate studies have not been conducted on this group. Regarding breastfeeding, it is noted that disodium salt passes into breast milk. Despite the fact that the substance is contained in small doses, the use of the product during lactation is not recommended. If there is such a need, you should first wean the child from breastfeeding.

In relation to children, studies have been conducted on various groups of patients except infants. In general, the drug has proven to be a safe drug that does not cause side effects when used adequately under the supervision of adults. No cases of drug overdose were identified.

  • Allergic conjunctivitis;
  • Allergic keratitis. But what are the symptoms and what should be the treatment for viral keratitis, this information will help you understand;
  • Allergic keratoconjunctivitis;
  • Eye irritation due to allergens.

Cromohexal in the form of eye drops is considered the most effective preventive agent, although in the acute phase it can eliminate the symptoms of allergic conjunctivitis. When used prophylactically, the effect may occur within a few days, and in some cases, several weeks from the start of administration.

Instructions for use

This remedy is considered the most effective preventive remedy, although in the acute phase it can eliminate the symptoms of allergic conjunctivitis. When used prophylactically, the effect may occur within a few days, and in some cases, several weeks from the start of administration. But what are the symptoms and what should be the treatment for conjunctivitis in adults, this article will help you understand.

The drug is used according to the following scheme:

  • Hands are washed with soap first.
  • Next, open the bottle and, pulling back the lower eyelid and looking upward, instill the solution 1-2 drops into each eye.
  • Then blink several times to evenly distribute the liquid over the entire surface of the mucous membrane of the eyeball. Tropicamide eye drops are also very helpful.

Video shows how to properly apply eye drops:

Try not to touch the tip of the bottle to your mucous membranes, eyelashes or eyelids to prevent pathogens from getting onto the bottle or into the solution. The solution is used up to 4 times a day in both adults and children. In general, the intervals between instillations should be 4-6 hours, but if necessary, you can increase the number of instillations up to 8 times a day.

Allergy therapy should be continued after symptoms have resolved. The course is the entire period of action of allergens. If therapy is aimed at eliminating the manifestations of chronic conjunctivitis, then the duration of use of the drops should be determined by the doctor.

No side effects have been recorded for the eye drops, but there is a risk of developing eye irritation. If these symptoms occur, you should stop using the medication and consult a doctor to change the drug. Contraindications for use are hypersensitivity, age under 2 years and the first trimester of pregnancy.

The drug contains cromoglycic acid (sodium cromoglycate) in an amount of 20 mg/ml. if the drug is used in people wearing contact lenses, the doctor must determine the possibility of using drops in each specific case. In the absence of contraindications, the use of drops is permitted, but only taking into account certain features.

The active component is capable of coloring lenses (you can find out what the best toric lenses are by reading the contents of this article), causing them to change color. That is why, before use, hard lenses are removed, after which the medicine is instilled into the conjunctival area according to the standard procedure. Next, the person must wait 15 minutes, after which, after pre-treating the lenses with an antiseptic, put them on again.

It is also worth considering that the drug may impair vision within a few minutes after instillation, but this effect quickly passes. This factor should be taken into account by people who use cars and complex equipment.

The cost of the drug varies depending on the pharmacy within rubles. The product is an affordable medicine, but can be addictive, according to customer reviews. In such cases, it is necessary to switch to an analogue with a similar effect.

Analogs

Analogs of the drug Cromohexal are such medications as:

These are structural analogues with cromoglycic acid in the composition. They provide a similar antihistamine effect. Their cost varies depending on the drug and the volume of the bottle, from 60 rubles and more.

Non-structural analogues are:

Allergodil

  • Alomide;
  • Ketofiren. But how and in what cases Tobrazon eye drops are used can be read here.

    Ketofiren

  • Zatiden;
  • Lastacaf;
  • Opatadine;
  • Opatanol. By clicking on the link you can learn more about the instructions for using the drops.;

    Opatanol

  • Pallas. But the information at the link will help you understand how Lecrolin eye drops are used.

    • Such drugs have different substances in their composition, but at the same time they have the same antihistamine effect. Before using any medicine, you should consult your doctor for contraindications.

    Source: http://okulist.online/zabolevaniya/lechenie/medikamenozonoe/kapli/kromogeksal-instrukciya-po-primeneniyu-glaznye.html

    Cromohexal ®

    Eye drops 2% in the form of a transparent, colorless to slightly yellowish solution without mechanical inclusions.

    Excipients: benzalkonium chloride - 0.1 mg, sodium chloride - 4 mg, disodium edetate - 1.5 mg, non-crystallized liquid sorbitol - 20 mg, sodium dihydrogen phosphate dihydrate - 1 mg, disodium hydrogen phosphate dodecahydrate - 5 mg, sodium hydroxide - up to pH 7.0, water d/i - 0.9661 mg.

    10 ml - polyethylene dropper bottle (1) - cardboard packs.

    Antiallergic drug. Mast cell membrane stabilizer.

    It has a membrane-stabilizing effect, blocks the entry of calcium ions into the mast cell, preventing its degranulation and the release of histamine, bradykinin, prostaglandins, leukotrienes (including slow-reacting substances) and other biologically active substances.

    The drug is most effective as a means of prevention. A noticeable clinical effect occurs a few days or weeks after administration.

    Suction and distribution

    Absorption through the mucous membrane of the eye is negligible. Systemic bioavailability is less than 0.03%. Communication with plasma proteins - 65%.

    Metabolism and excretion

    Not metabolized. It is excreted unchanged by the kidneys and through the intestines (in approximately equal amounts within 24 hours after use). T 1/2 minutes.

    Prevention and treatment:

    - allergic keratitis, keratoconjunctivitis;

    - irritation of the mucous membrane of the eyes caused by allergic reactions (environmental factors, occupational hazards, household chemicals, cosmetics, ophthalmic dosage forms, plants and pets).

    For adults and children over 2 years of age, instill 1-2 drops into each conjunctival sac 4 times a day with an interval of 4-6 hours. If necessary, the dose can be increased to 6-8 instillations.

    After achieving a therapeutic effect, the frequency of use of the drug can be reduced and Cromohexal ® can be used only when in contact with allergens (house dust, fungal spores, pollen).

    From the organ of vision: impaired clarity of visual perception, burning in the eye, swelling of the conjunctiva, foreign body sensation, dry eyes, lacrimation, meibomitis (styre); superficial damage to the corneal epithelium.

    - children under 2 years of age;

    - hypersensitivity to sodium cromoglycate or to any other component of the drug.

    with caution in children under 4 years of age, during pregnancy and lactation.

    Cromohexal ® should be used with caution during pregnancy and lactation.

    The use of the drug Cromohexal ® reduces the need for the use of ophthalmic drugs containing glucocorticoids.

    When using Cromohexal ® drops, due to the benzalkonium chloride content, you should avoid wearing soft contact lenses; Hard contact lenses must be removed 15 minutes before instillation and put on after 15 minutes.

    The bottle must be closed after each use. Do not touch the tip of the pipette to your eye.

    Impact on the ability to drive vehicles and operate machinery

    During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

    There are no data on drug overdose.

    To date, no interactions with other drugs have been identified.

    The drug should be stored in a place protected from light, out of reach of children, at a temperature not exceeding 25°C. Shelf life: 3 years.

    Opened bottles should be used within 6 weeks.

    The scientific information provided is general and cannot be used to make a decision about the possibility of using a particular drug.

    There are contraindications, consult your doctor.

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    Source: http://health.yandex.ru/pills/kromogeksal-42661

    "Cromohexal" (eye drops): instructions for use, reviews and prices

    Every second person now knows what an allergy is. Either he himself or his relatives encountered its manifestations. Therefore, antihistamines have become very popular in pharmacies. One of them is Cromohexal, an eye drop produced by a German pharmaceutical company. After all, an allergy is not just a skin rash or sneezing. Very often it manifests itself as severe itching of the eyes. Without proper treatment, such allergic reactions lead to conjunctivitis or purulent keratitis. Scratching the eyes can cause infection in the conjunctiva, which in severe cases can cause vision loss. Therefore, everyone who suffers from seasonal or household allergies should have Cromohexal (eye drops) in their home medicine cabinet.

    Instructions for use: dosage

    The effect of the drug begins some time after it is instilled into the eyes. But the maximum effect is observed only after a couple of days. Therefore, you need to use Cromohexal (eye drops) to prevent seasonal allergies several days before its possible onset. The drug contains strong chemicals, so it is used only as prescribed by a doctor. You should definitely consult on the dosage of the medicine and the duration of treatment. Cromohexal (eye drops) is usually well tolerated by most patients. Instructions for use recommend instilling 1-2 drops into each conjunctival sac, no more. Do this every 5-8 hours. For most patients, this dosage is sufficient, but with severe manifestations of allergies, the frequency of use can be increased to 8 times a day. It is recommended to instill the drug less frequently after achieving a therapeutic effect. In the future, drops are used when exposed to allergens and during seasonal hay fever.

    Composition of the drug and release form

    The main active ingredient of the drug is cromoglycic acid. It has a very strong effect and is contained in drops in the form of sodium cromoglycate. Its concentration is only 2%. The drug is produced in small plastic dropper bottles to make it easier to maintain the dosage. What other substances does Cromohexal (eye drops) contain?

    — Sodium monohydrogen phosphate and dihydrogen phosphate.

    How do the drops work?

    The effectiveness of the drug is based on the ability of cromoglycic acid to act directly on the membranes of mast cells. These are the cells that are responsible for the production of hormones that cause a reaction to various allergens. And cromoglicic acid prevents the release of histamine, prostaglandins and leukotrienes. In addition, it blocks the movement of calcium ions. That is why Cromohexal so quickly stops and prevents the occurrence of allergic reactions. These eye drops also have the following effect:

    - relieve itching and irritation of the eyes, the feeling of sand and foreign body on the eyeball;

    - eliminate dryness, as they moisturize the mucous membrane of the eyes;

    - have an anti-edematous effect;

    - relieve redness of the conjunctiva.

    Indications for use

    The drug is often prescribed in the complex treatment of many ophthalmological diseases and allergic reactions:

    - acute and chronic conjunctivitis;

    - acute and chronic keratitis and keratoconjunctivitis;

    - itching and redness of the eyes due to hay fever;

    — prevention of allergic reactions;

    - to relieve dryness and irritation of the eyes when they are overstrained, when exposed to dust, wind or cosmetics.

    Contraindications and side effects

    The drug is ineffective against viral and infectious conjunctivitis, cataracts and myopia. Therefore, you can use it only after the recommendation of a doctor. Not everyone can use Cromohexal (eye drops). The instructions warn against their use by pregnant and lactating women. Cromoglycic acid passes into milk and can adversely affect the baby. Sometimes individual intolerance to the components of the drug occurs. In this case, Cromohexal (eye drops) is also not used. The drug is contraindicated for children under 4 years of age, and for older children it can only be used as prescribed by a doctor.

    Some patients do not like the fact that often after instillation of the drug, symptoms of eye irritation intensify: itching, burning and the sensation of a foreign body in the eye. But usually it goes away after a few minutes. Sometimes there is also a decrease in visual acuity. In severe cases, there may be swelling and hyperemia of the conjunctiva or the development of barley. Because of this, many allergy sufferers are forced to abandon the use of such effective drops.

    special instructions

    — The drug should be warm when instilled, so it is recommended to slightly warm the bottle in your hands.

    - Only less than 7% of the drug is absorbed into the blood and after a day is excreted unchanged in bile and urine. But if it is necessary to use Cromohexal for a long time, you need to monitor the condition of the liver and kidneys.

    — It is not advisable to use the drug simultaneously with other eye drops. At least a minute should pass between instillation of the two drugs.

    — While using drops, you should stop using soft contact lenses, and hard ones should be taken out and put back on only 15 minutes after instillation.

    — It is advisable to use an open bottle within 6 weeks, otherwise the drug will only harm the eyes.

    — For the same reason, it is not advisable to touch the dropper spout with your hands or touch your skin with it.

    — If during the day the manifestations of allergies do not decrease, but, on the contrary, intensify, then you should stop using Cromohexal (eye drops).

    Reviews about the drug

    With frequent hay fever or hay fever, patients are ready to buy any medicine. One of the most commonly used is Cromohexal (eye drops). Its price is small - about 100 rubles, but its effectiveness is quite high. After using the drops, patients note the effectiveness of the drug. Many people like its low cost and the fact that when using it, they can avoid expensive antihistamines. Some even used it for children under 4 years old, however, after the recommendation of a doctor, and did not observe any side effects.

    Many people note that Cromohexal (eye drops) helps with eye fatigue after long periods of working at the computer. Its price is much lower than other similar drugs. Therefore, of all the drugs used in ophthalmology, these drops are the most common and popular among both doctors and patients.

    What can replace Cromohexal?

    There are patients who cannot tolerate these drops or cannot find them in the pharmacy. In this case, they can be successfully replaced with another drug. What are the most famous and effective analogues of Cromohexal?

    — “Vizin” also relieves swelling and irritation of the eyes and can be used for allergies.

    “Opatanol” has a similar effect, but is slightly better tolerated by patients.

    — “Okumetil”, in addition to its antihistamine and anti-edematous effects, has an anti-inflammatory effect.

    “Lecrolin” is absolutely identical to these drops, since it has the same composition.

    - “Opticrom”, “Ifiral”, “Vividrin”, “Cropoz” and some others are also absolute synonyms of “Cromohexal”.

    — “Allergodil” is very similar to “Cromohexal” both in composition and in its mechanism of action, although it has a different active ingredient.

    Source: http://www.syl.ru/article/203238/new_kromogeksal-glaznyie-kapli-instruktsiya-po-primeneniyu-otzyivyi-i-tsenyi