How long does it take for Claritin to work?

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Claritin

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Pharmacological properties of the drug Claritin

Pharmacodynamics. Claritin is an antihistamine, a selective blocker of peripheral H1-histamine receptors. Clinical studies have shown that improvement in the condition of most patients began within the first 30 minutes of using Claritin.

Table of contents:

The antiallergic effect develops during the first 30 minutes after taking the drug, reaches a maximum within 8–12 hours and lasts 24 hours. Loratadine and its metabolites do not penetrate the BBB. Claritin does not affect the central nervous system, does not exhibit anticholinergic or sedative effects, and does not affect the speed of psychomotor reactions. In a clinical study in which Claritin was used for 90 days at a dose that was 4 times higher than the therapeutic dose, no clinically significant prolongation of the QT interval was detected on the ECG.

Pharmacokinetics. Claritin is rapidly absorbed into the gastrointestinal tract. The time to reach the maximum concentration of loratadine in the blood plasma is 1–1.3 hours, and the time to reach the maximum concentration of the main metabolite, desloratadine, is approximately 2.5 hours. Eating increases the time to reach the maximum concentration of loratadine and desloratadine by 1 hour. The maximum concentration of loratadine and desloratadine is not affected by food intake. The maximum concentration increases in elderly patients, patients with chronic renal failure or alcoholic liver damage.

In almost all cases, the level of influence of metabolites is higher than the level of influence of the parent substance. Determinable concentrations appear in the blood plasma within 15 minutes after taking the drug orally. A comparative study of the use of Claritin syrup and tablets in adequate doses showed that the plasma concentration profile of desloratadine for both dosage forms is comparable.

An in vitro study of human liver microsomes revealed that loratadine is metabolized to desloratadine mainly under the influence of cytochrome P450 3A4 (CYP 3A4) and to a lesser extent cytochrome P450 2D6 (CYP 3D6). The half-life is 8.4 hours for loratadine, 28 hours for its metabolites. About 27% of the administered dose is excreted in the urine during the first 24 hours. In the presence of ketoconazole, a CYP3A4 inhibitor, loratadine is converted to desloratadine primarily by CYP3D6. The half-life increases with alcoholic liver damage and does not change in the presence of chronic renal failure.

The pharmacokinetics of Claritin in children aged 1–2 years when prescribed a single dose of 2.5 mg does not differ from those in adults and older children.

Indications for use of the drug Claritin

Seasonal (polynosis) and year-round allergic rhinitis and allergic conjunctivitis - elimination of symptoms associated with these diseases: sneezing, itching of the nasal mucosa, rhinorrhea, burning sensation and itching of the eyes, lacrimation. Chronic idiopathic urticaria. Skin diseases of allergic origin.

Use of the drug Claritin

Adults and children ≥12 years old - 10 mg (1 tablet) 1 time per day;

children aged 2–12 years with a body weight of 30 kg - 10 mg (1 tablet) 1 time per day, with a body weight ≤30 kg - 5 mg (1/2 t tablet) 1 time per day;

children aged 1–2 years - 2.5 mg (1/4 t tablet) Claritin 1 time per day.

Adults and children aged ≥12 years - 10 mg (2 scoops - 10 ml syrup) 1 time per day;

children aged 2–12 years with body weight ≥30 kg - 10 mg (2 measuring spoons - 10 ml of syrup) 1 time per day, ≤30 kg - 5 mg (1 measuring spoon - 5 ml of syrup) 1 time per day;

children aged 1–2 years - 2.5 mg (1/2 measuring spoon - 2.5 ml of syrup) 1 time per day.

Contraindications to the use of the drug Claritin

Hypersensitivity (or idiosyncrasy) to any of the components of the drug.

Side effects of the drug Claritin

The incidence of side effects with Claritin is approximately the same as with placebo. Side effects such as fatigue, headache, drowsiness, dry mouth, gastrointestinal disorders (nausea, gastritis), allergic rash were noted. During the studies, isolated cases of alopecia, anaphylaxis, liver dysfunction, tachycardia and palpitations were observed.

Special instructions for the use of Claritin

Claritin does not have a clinically significant sedative effect when used in recommended doses (10 mg once daily). Claritin does not potentiate the effects of alcohol. At recommended doses, it does not affect the ability to drive vehicles or operate complex machinery.

Claritin should be discontinued at least 48 hours before skin diagnostic allergy tests are performed to prevent false results.

For patients with severe liver dysfunction, the initial dose should be reduced due to a possible decrease in the clearance of loratadine (an initial dose of 5 mg once daily or 10 mg every other day is recommended).

Use in children. The effectiveness and safety of Claritin in children under 1 year of age has not been proven. It should be noted that the pharmacokinetics of Claritin in children aged 1–2 years when prescribed a single dose of 2.5 mg does not differ from the pharmacokinetics of adults and older children.

Use during pregnancy and lactation. The safety of using the drug during pregnancy has not been established, therefore Claritin should be used only if the benefits of its use for the mother outweigh the potential risk to the fetus. Since loratadine is excreted in breast milk, a choice must be made between taking the drug and breastfeeding.

Drug interactions Claritin

When loratadine was taken simultaneously with ketoconazole, erythromycin, cimetidine, an increase in the concentration of loratadine in the blood plasma was noted, but this increase did not manifest itself clinically, including according to ECG data.

Claritin overdose, symptoms and treatment

In case of overdose, drowsiness, tachycardia and headache may occur. With a single dose of 160 mg, no side effects were noted (including ECG changes). In case of overdose, symptomatic and supportive treatment is recommended. Standard measures are recommended to remove unabsorbed drug from the stomach: gastric lavage, taking activated charcoal. Loratadine is not eliminated by hemodialysis. After emergency treatment, the patient should remain under medical supervision.

Storage conditions for the drug Claritin

In a dry place at a temperature not exceeding 25 °C.

Source: http://www.minclinic.ru/drugs/K/klaritin.html

Claritin - instructions for use, composition, indications, analogues and reviews

Claritin is an anti-allergy medication that is a selective blocker of peripheral histamine receptors. The active ingredient in Claritin is loratadine. Loratodine is a tricyclic compound characterized by a pronounced antihistamine effect. Claritin is highly effective in the fight against allergies, with fast and long-lasting action.

Composition and release form

  • Tablets of 10 mg are available in blisters of 7, 10 and 30 pieces.
  • The syrup is available in dark glass bottles of 60 and 120 ml. Measuring spoon included.

The medication must be stored out of the reach of children at a temperature of +2 to +20 degrees. The shelf life of tablets is 4 years, syrup – 3 years.

Composition of Claritin tablets

  • The active substance is loratadine 10 mg.
  • Excipients : lactose monohydrate, corn starch, magnesium stearate.

Composition of Claritin syrup

  • The active substance is loratadine 1 mg/ml.
  • Excipients - propylene glycol, glycerol, citric acid monohydrate (anhydrous alternative citric acid), sodium benzoate, sucrose (granulated), artificial flavor (peach), purified water.

Claritin instructions for use in various dosage forms

Recommendations for use in tablets

Claritin tablets are taken orally with water; administration does not depend on meals. For adults and elderly patients, as well as adolescents over 12 years of age, it is recommended to use Claritin in a dose of 1 tablet once a day. Children aged 2 to 12 years are prescribed a dose depending on body weight. With a body weight of less than 30 kg, half a tablet is prescribed once a day, with a body weight of more than 30 kg - 1 tablet once a day.

No dose adjustment is required in patients with chronic renal failure. For patients with liver failure, the initial dose is 1 tablet every other day, for children whose body weight is less than 30 kg - half a tablet every other day.

Claritin: use in syrup form

Claritin syrup is taken orally, regardless of meals. Adults and children over 12 years of age are prescribed 2 teaspoons of syrup once a day. Children whose body weight is less than 30 kg are supposed to use 1 teaspoon, that is, 5 ml of syrup, 1 time per day. Children weighing more than 30 kg should take two teaspoons of medication once a day.

For patients with liver diseases, adjustments to the dose of the medication are required; they are prescribed the same doses of syrup, but they should be used every other day.

Special instructions for using Claritin

To avoid distorting the results of skin tests taken for diagnostic testing, it is necessary to stop taking Claritin 48 hours before diagnosis, as antihistamines may affect the result. Claritin does not cause a pronounced sedative effect, nor does it cause drowsiness or slow psychotropic reactions, so Claritin does not affect driving or performing other activities that require concentration.

In very rare cases, patients taking Claritin may experience fatigue for no apparent reason, which may lead to decreased ability to drive. For patients with renal impairment, dose adjustment is required; they should use no more than 10 mg every other day. In case of liver failure, Claritin is prescribed with caution, in small doses.

Indications, contraindications, side effects of the drug Claritin

Indications for use of Claritin

The medication is indicated for all types of allergies, in particular, Claritin is indicated for seasonal and year-round rhinitis, allergic conjunctivitis, chronic urticaria and any skin diseases of allergic origin. The medication effectively combats itching of the mucous membrane and oral cavity, sneezing, burning eyes, watery eyes, and rashes.

Side effects from using the drug Claritin

With continuous use of the drug, the following side effects are possible:

  • From the digestive system: dry mouth, nausea, in rare cases, gastritis and liver dysfunction occur.
  • Allergic reactions are possible - skin rash, in rare cases anaphylactic reactions are observed.
  • From the central nervous system - headaches, fatigue, drowsiness. In children, side effects of this kind are rare and may include nervousness, lethargy, and headaches.
  • Alopecia in isolated cases.

Clinical studies have shown that the most common use of Claritin in children causes headaches, and in adults, the most common side effect from the central nervous system was drowsiness. Moreover, the frequency of side effects when taking the drug did not differ from the same effects when taking placebo.

Contraindications for using Claritin

The use of Claritin is contraindicated in children under 2 years of age. Taking tablets is not recommended for children under 3 years of age. The medication is also contraindicated in the following cases:

  • Lactation period.
  • Hypersensitivity and intolerance to the active substance, as well as excipients.
  • Some hereditary diseases, such as poor tolerance to galactose, lactose deficiency, since the tablets contain lactose.
  • Fructose intolerance.
  • Deficiency of sucrase, which is part of the syrup.

Patients with impaired liver function should use Claritin with great caution.

Claritin: symptoms of overdose

In case of overdose, patients experience drowsiness, headache, and tachycardia. An overdose occurs when taking a drug in doses of mg, that is, those that greatly exceed the recommended therapeutic dose. The use of Claritin in children in the form of syrup at a dose of more than 10 mg causes increased heart rate.

If such symptoms occur, symptomatic and supportive therapy is necessary. Hemodialysis is ineffective in such cases and is therefore not used.

How long can you use Claritin?

Allergy medications must be taken in advance, before irritants appear. The use of Claritin does not cause a negative effect on the body’s condition, so it can be used during the entire period during which patients develop an allergy and a couple of weeks before its onset.

Use of Claritin during pregnancy

The safety of the effects of loratadine on the body of a pregnant woman has not been thoroughly studied. The use of Claritin is permitted during pregnancy if the benefit to the mother is greater than the expected risk to the child. Loratadine passes through breast milk to the baby, so if it is necessary to use it during lactation, breastfeeding must be temporarily stopped.

Claritin: use for children

Children over 2 years of age are prescribed Claritin in the form of syrup in small doses. Children over 3 years of age are allowed to take the medicine in tablet form, in doses determined depending on the child’s weight.

How Claritin works

Claritin does not affect the central nervous system. Unlike many anti-allergy drugs, Claritin does not have a sedative effect and does not reduce the rate of psychotropic reactions. The use of Claritin does not lead to prolongation of the QT interval on the ECG. The drug does not have a significant effect on vital signs, physical examination, laboratory results, or ECG.

The active substance of the drug does not have significant selectivity for histamine receptors. The drug does not inhibit norepinephrine reuptake and has no effect on the cardiovascular system. The medication begins to act 30 minutes after oral administration. The maximum concentration of the product is achieved after 8-12 hours and persists for 24 hours.

The medication is absorbed from the gastrointestinal tract. The half-life in blood plasma is 1-1.5 hours. Eating increases the half-life of the medication, but does not affect its medicinal properties and does not change its effects. The bioavailability of the drug depends on the dose taken.

Loratadine is highly bound to plasma proteins, this binding reaches 97-99%. Claritin is metabolized to form desloratadine. The medication is excreted by the kidneys and through the intestines. 40% of the drug is excreted through the kidneys, 42% through the intestines. Withdrawal is carried out within 10 days, the main part is excreted in the form of conjunctive metabolites.

Interaction of Claritin with other drugs

The combination of Claritin with ketoconazole, cimetidine, erythromycin may cause an increase in the concentration of loratadine and its metabolite in the blood plasma. This increase does not lead to clinically significant changes in heart function, as shown by the ECG. Claritin does not enhance the effect of ethanol on the central nervous system, that is, alcohol does not affect the effectiveness of using the drug.

Analogues of Claritin: domestic and foreign

Alerpriv - an analogue of Claritin

The medication blocks histamine receptors and has an antiallergic effect, relieves itching and redness. The drug reduces capillary permeability and prevents the occurrence of edema. In addition, the drug reduces the contractile activity of smooth muscles.

Claritin analogue - Clargotil

Clargotil is a good antiallergic agent that has an antipruritic effect, relieves redness, and relieves swelling. The drug prevents the occurrence of signs of allergy and does not affect the central nervous system. The substance acts within 30 minutes after administration.

The drug inhibits the release of histamine. Claridol is used as an allergy preventative and also as an effective allergy symptom reliever. This analogue does not affect brain function, does not provoke inhibition of reactions, and does not cause drowsiness. The drug begins to act 30 minutes after taking the drug, its maximum effect occurs after 8-12 hours, and the duration of the effect reaches a day.

Analogue of Claritin - Lomilan

The anti-allergy drug is a histamine receptor blocker, intended for systemic use. The drug prevents the occurrence of edema, relieves signs of allergies and prevents their occurrence. lofy is a fast-acting drug, does not affect the functioning of the central nervous system and brain function, and is not addictive.

Analogue of the drug Claritin - Lotharen

A fast-acting antiallergic drug that relieves all signs of allergy and reduces increased contractile activity of tissues.

Tirlor is an analogue of Claritin

A highly effective anti-allergy drug, it relieves all signs of allergies and prevents their development. The drug does not affect the functioning of the heart. This analogue is not addictive and does not affect the functioning of the central nervous system.

Price of the drug in pharmacies

Check out the price of Claritin in 2018 and cheap analogues >>> The cost of Claritin in different pharmacies can vary significantly. This is due to the use of cheaper components in the drug and the pricing policy of the pharmacy chain. But the important thing is that the price difference between foreign and Russian analogues remains almost unchanged.

On the MedMoon.ru website, medications are classified both alphabetically and by effect on the body. We publish only the most current and new medications. Instructions for use of Claritin are regularly updated at the request of manufacturers.

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Source: http://www.medmoon.ru/medicina/Klaritin_instrukciya.html

Claritin - instructions for use for children and adults, indications, composition, side effects, analogues and price

According to WHO statistics, from 30 to 60 percent of the world's population are susceptible to allergies. This is due to environmental pollution, the use of synthetic additives in food production, and the development of the household chemical industry. But at the same time, pharmacology is also developing, offering reliable and safe medications for allergies. An effective remedy for reducing histamine, treating seasonal runny nose, relieving swelling, rashes and itching is Claritin - the instructions for use will tell you in detail about the use and contraindications of the drug.

Claritin for allergies

The main task of anti-allergenic drugs and antihistamines is to block H1 receptors and reduce the level of histamine in the blood. But, in addition, it is also necessary to eliminate the accompanying skin and respiratory allergic symptoms of the disease:

  • cough;
  • itching;
  • runny nose;
  • swelling;
  • skin diseases - rash, redness;
  • tearfulness;
  • inflammation.

Most antiallergens only block histamine H1 receptors, and to eliminate other allergy symptoms it is necessary to take other medications that negatively affect the organs and general health of a person. Claritin solves all problems comprehensively, and can also be used for preventive purposes. According to the American pharmacological company IMS, it is the most prescribed medicine for allergies. The drug belongs to the latest generation of selective blockers; it is used and recommended by doctors in more than a hundred countries around the world.

Composition and release form

Claritin is sold in the form of tablets and syrup:

White oval tablets. One side is smooth, on the other side there is a dividing notch, an engraving of the trademark in the form of a bowl and flask, and the number 10

Lactose, corn starch, stearic acid

Blister packaging (blister) for 7, 10 or 15 tablets

The syrup is colorless and transparent, sometimes with a golden tint. Without impurities and sediment

Distilled water, citric acid, sodium benzoate, glycerol, propylene glycol, sucrose, peach synthetic flavor

Glass bottle 60 ml or 120 ml in a cardboard box. Comes with a measuring spoon or dispenser (syringe)

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Pharmacodynamics and pharmacokinetics

The active substance loratadine is an antihistamine tricyclic chemical compound that has a blocking effect on peripheral H1 receptors. The antiallergic effect of Claritin begins within half an hour after ingestion, and the main symptoms of the disease disappear. The maximum antihistamine effect is achieved after 8-12 hours and lasts for 24 hours. Does not affect the nervous system, does not have a sedative effect. With long-term use, no significant deterioration in the vital functions of the body is observed.

Quickly absorbed into the gastrointestinal tract. If you take the medicine before meals, the maximum concentration of the substance will occur an hour later, but the overall level of loratadine concentration in the blood is not affected by food intake. The maximum concentration increases only in elderly people, with chronic or terminal renal failure, and liver diseases caused by alcohol. During metabolism, part of loratadine is produced into the selective blocker desloratadine. Both components are excreted in the form of conjugated final metabolites in urine and bile:

  • The half-life of loratadine ranges from 3 to 20 hours;
  • The half-life of desloratadine is from 8 to 92 hours.

Indications for use

It is used for the following allergic reactions and diseases:

  1. Chronic idiopathic urticaria.
  2. Various dermatological diseases and other allergic skin reactions.
  3. For seasonal or year-round allergic rhinitis to eliminate:
  • runny nose;
  • sneezing;
  • inflammation and itching of the nasal mucosa.
  1. For seasonal or year-round allergic rhinoconjunctivitis (hay fever) eliminates:
  • lacrimation;
  • itching and burning in the eye area.

Directions for use and dosage

Claritin is taken orally, before or after meals. Taking the medicine does not depend on the time of eating; the only thing that needs to be taken into account is that the effect of the medicine taken on an empty stomach will begin an hour earlier than after eating. Claritin in any form is contraindicated for children under 2 years of age. It is necessary to limit the dosage of the medication for people suffering from serious diseases and liver pathologies. In such cases, it is recommended to consult a doctor.

Pills

The dosage for adults and children over 12 years of age is 10 ml once a day - that’s 1 tablet. The same dose of medication can be taken by elderly people, patients with chronic and end-stage renal failure. For children from 3 to 12 years old, the dose is calculated depending on body weight. A child whose weight is 30 kilograms or more is given 1 tablet (10 ml) 1 time per day, with a lower weight and children from 2 to 3 years old, tablets are prohibited.

Syrup

For adult patients, syrup is prescribed two teaspoons (10 ml) once a day. For children from two to three years old and weighing less than 30 kilograms, the permissible dose of syrup is 1 teaspoon or 5 ml per day. For people, including children weighing more than 30 kilograms, with severe liver damage and impairment of its functions, the permissible initial dose is no more than 10 ml of the drug (2 teaspoons) once every two days. If for the same diseases the body weight is less than 30 kilograms, the initial dosage will be half as much - 5 ml (1 teaspoon of syrup) every 48 hours.

special instructions

You should not take Claritin less than 48 hours before taking allergy skin tests (allergy tests). Because antihistamines contained in the drug can distort the results of the analysis, which will not allow a correct diagnosis. The drug has a sedative effect and does not reduce concentration or psychomotor reactions. The drug does not have a direct contraindication to driving a car or other mechanical means, but sometimes the medication can cause drowsiness and have a sedative effect.

During pregnancy

Clinical studies have not clearly established the safety of taking Claritin during pregnancy. Pregnant women are allowed to take the medicine in special cases if the expected benefit for the woman is higher than the potential danger to the health of the fetus. Claritin is not recommended during breastfeeding, because the active substances of the drug (loratadine metabolite) partially enter the mammary glands and breast milk. In this case, a doctor's recommendation is required.

For children

According to experts, Claritin is the safest anti-allergen for children's bodies. It is used by pediatricians in many countries. When taking other similar medications for more than 10 days, the body begins to get used to them. The effectiveness of treatment decreases, and the risk of side effects increases, which are sometimes impossible to predict in a child’s body. The drug does not have a harmful effect on the child’s health. Children's Claritin is prescribed both for short-term treatment for acute attacks of allergies, and for long-term therapy for relapses of the disease - up to 12 months.

Drug interactions

During clinical studies of Claritin, no particularly significant interactions of its components with other medical or pharmacological drugs were found. There are some reactions of loratadine (a slight increase in its dose in the patient’s blood) while taking Claritin and antibiotics, an antifungal agent. A minor and harmless reaction occurs when interacting with the following medications:

Claritin and alcohol

The active and auxiliary components of Claritin, which are metabolized after taking the drug desloratadine, do not penetrate the human brain centers. The drug has no effect on the central nervous system and does not enhance the harmful effects of alcohol. But you need to take into account that this is general data, and everyone’s body characteristics are different. In each individual case, it is impossible to accurately predict what the consequences of the interaction of medication and alcohol may be. This applies to any medication.

Side effects

Like any medicine, Claritin has certain side effects, but they do not exceed the effects on the body of a placebo drug (a harmless substance manufactured under the guise of a medicine to create the effect of self-hypnosis that it can cure a disease). The frequency of side effects of Claritin does not exceed 2%; according to patient reviews, in rare cases the following may be observed:

  • dry mouth;
  • nausea;
  • skin rash;
  • short-term dizziness;
  • drowsiness was noted;
  • cardiopalmus;
  • nervousness.

Overdose

With a slight increase in dose, there is no negative reaction or effect on the body. Adverse effects for an adult can only be caused after increasing the dosage by at least four times (4 mg of loratadine), in children after taking a dose of the drug twice the recommended dose. In case of an overdose of the drug, adsorbents, gastric lavage with a 10% solution of sodium chloride (table salt), and activated carbon are prescribed. Overdose symptoms:

  • painful palpitations;
  • headache;
  • loss of strength, drowsiness.

Contraindications

Claritin is contraindicated in case of high individual sensitivity of the patient to the components of the drug, especially to loratadine. Reasons for refusing to take medication may include:

  • Hereditary diseases associated with low levels of Lapp lactase in the body.
  • If the body reacts negatively to galactose, which is part of Claritin tablets. In this case, syrup will do.
  • During breastfeeding.
  • Age up to two years for syrup, and up to three years for tablets.

Terms of sale and storage

Available in pharmacies without a prescription. Store out of the reach of children at a temperature of 2 to 25 degrees Celsius. Keep the syrup in a dark place, away from direct sunlight. Shelf life for tablets is 4 years, syrup – 3 years.

Analogs

Claritin has no absolute analogues regarding the complex treatment of allergies, the period of taking the medicine, the risks of formation and development of side effects. But in terms of the presence of loratadine in the composition and the angistaminic effect it corresponds to:

Tablets, blister packaging 7 pcs.

Labo NV, Belgium

Tablets, blister pack 10 pcs.

Tablets, blister pack 10 pcs.

Syrup 60 ml, complete with dosing spoon

Labo NV, Belgium

Syrup 60 ml, complete with dosing spoon

Syrup 60 ml, complete with dosing spoon

Video

Reviews

Lidia Ivanovna, 52 years old

I was allergic to medications for stomach ulcers. A rash appeared on my knee and became so swollen that it was painful to walk. The result of Claritin was after the first pill: the itching and inflammation went away, I was able to move around without pain. On the third day, all symptoms disappeared altogether. The great thing is that it does not cause drowsiness like suprastin, which I once used to treat tracheitis.

It is not clear why, about five years ago an allergy to cat hair appeared. If I go to a friend who has a cat, then skin manifestations (rashes and blisters) are guaranteed. I tried different tablets and drops, but only Claritin really helps. I take a pill an hour before coming to the apartment where the cat is, and everything is fine - no hives.

The first time I chose Claritin by chance, the pharmacy gave me a good review. I had a severe allergy attack - my eyes itched, I began to choke, as if I had asthma. Helped quickly. Literally after 15 minutes it becomes much easier. But it does make you drowsy. And it doesn’t last for 24 hours, as the annotation says, but for 12 hours. I don’t know, maybe it depends on the body.

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and make recommendations for treatment based on the individual characteristics of a particular patient.

Source: http://sovets.net/14591-klaritin-instrukciya-po-primeneniyu.html

What does Claritin help with?

The pharmacological agent Claritin refers to medications that eliminate pronounced allergic reactions. In addition, the medication is often used to prevent various chronic diseases that occur against the background of allergic inflammatory processes. Such diseases include bronchial asthma.

The medication belongs to the group of antihistamines that have a selective effect. Thus, the medicine acts only on those organs that are involved in allergic processes. Allergy tablets Claritin allow you to get rid of allergies in a short time, without the appearance of side effects while taking the medication.

Claritin is a drug that eliminates allergy symptoms during attacks

What is Claritin

Claritin is manufactured by the Belgian company Schering-Plough Labo N.V. in the form of a solution for children and tablets for adults. The medicine, produced in the form of a solution, is often called children's Claritin, since the dosage of the drug is designed specifically for children.

This solution is completely transparent and does not contain dyes or impurities. It is bottled in glass bottles with a dark color. The volume of the bottle can be sixty or one hundred twenty milliliters; a measuring spoon is included with the solution.

Claritin, available in tablets, is oval-shaped and white in color. A distinctive feature of these tablets is that on one of their sides there is an emblem depicting a flask or bowl. One package of medication may contain seven, ten, twenty or thirty tablets.

The active substance in this medication is loratadine. One tablet contains about ten milligrams of this substance, and one milliliter of syrup contains one milligram.

Therapeutic effect

The medication has antiallergic, antihistamine and itching-soothing effects. All of the above actions are achieved due to the fact that the active component of the drug blocks the receptors responsible for the formation of an allergic reaction. It only takes thirty minutes for the drug to be activated. The duration of action of the drug Claritin is twenty-four hours.

The advantages of the medication are that the active substance loratadine cannot penetrate the blood-brain barrier. This suggests that the drug does not communicate with those receptors that are associated with the central nervous system. Against this background, taking the tablets is not accompanied by a sedative effect.

When to use the medicine

Let's take a closer look at what Claritin helps with. The instructions for use of this pharmacological agent indicate the need for its use in the following situations:

  • hay fever - a runny nose that has a seasonal allergic form;
  • urticaria, which has a chronic form;
  • conjunctivitis and runny nose due to allergies;
  • dermatitis, eczema and Quincke's edema;
  • pseudo-allergic reactions due to food consumption.

Using tablets, you can eliminate symptoms such as: a feeling of nasal congestion, swelling and itching, runny nose, sneezing and skin rashes.

The drug Claritin has antiallergic, antihistamine and antipruritic effects.

Reception scheme

Claritin tablets, instructions for use contain several dosage regimens. Each form of this medication can be taken at any time of the day.

One of the advantages of the drug is that its use does not depend on food intake.

When choosing a dosage, it is necessary to take into account the person’s age and the severity of the allergic reaction. It is best for children under three years of age to take syrup. Starting from the age of three, the use of tablets is allowed.

The medication should be taken once a day. The maximum daily dose is two tablespoons of syrup or one tablet. In cases where the drug is taken by children under twelve years of age, the dose of the drug should be calculated based on weight. So, if you weigh less than thirty kilograms, it is recommended to take half a tablet or one spoon of syrup once a day. In such situations, it is best to use syrup, since this form allows you to more accurately determine the required dose.

If you are about to undergo an allergy test, you should stop using the medication. Experts say that it is best to stop taking Claritin seventy-two hours before the tests.

This product should be used with great caution; violating the recommended dosage may lead to side effects. Typically, an overdose is expressed by symptoms such as migraine attacks, weakness and rapid heartbeat. In a situation where the dose has been exceeded, the child may experience extrapyramidal symptoms. These symptoms include tremors, involuntary movements of the limbs, muscle cramps, a distorted face and twitching of the lips.

In case of overdose, it is very important to perform gastric lavage as quickly as possible. To do this, you can use saline solution, soda or potassium permanganate. After the procedure, you must take an adsorbent.

Drug combinations

Combinations of the drug with medications such as ketoconazole and erythromycin may cause an increase in the concentration of loratadine in the bloodstream. This factor must be taken into account in order to prevent an overdose of an antiallergenic drug.

Claritin blocks histamine receptors, preventing the development of an allergic reaction

Children's Claritin

Syrup can be used to treat allergies only if the child is over two years old. For treating children, it is best to use syrup, since this form of medication allows you to more accurately calculate the dose. It is based on this fact that the syrup is called children's Claritin. When the child's age exceeds three years, the use of tablets is allowed.

Weight plays a major role in the dosage of the drug. It is enough to use the medication once a day. Experts say that for the best effect of the medicine, it must be used at the same hours.

Claritin has two dosage regimens, which are based on the patient's weight. So, if the child’s weight exceeds thirty kilograms, it is recommended to use one tablet or one scoop of syrup. When the child's weight is less than the value given above, it is recommended to take half a tablet or one dessert spoon of syrup.

The course of medication is based on the severity of allergy symptoms.

The maximum permitted course duration is two weeks. In certain situations, the medicine can be used every other day.

When the medication is taken for preventive purposes, Claritin can be used for quite a long time. Sometimes experts prescribe syrup for infants, since the medication does not interact with the central nervous system and allows you to quickly relieve the symptoms of an allergic reaction. In such situations, a reduced dosage is used. Thus, children under one year of age are recommended to consume no more than one and a half milliliters of syrup, and children whose age exceeds one year, three milliliters of the medicine once a day.

Use during pregnancy

Medical experts say that the use of Claritin during pregnancy is permissible only if its beneficial effect outweighs the possible risks.

During clinical trials, no negative effects on the developing fetus were identified. However, there is a certain risk of the medication affecting the development of the embryo. Doctors say that the medicine should be used only when the allergy is severe. In other cases, it is best to stop using the medication.

During breastfeeding, taking Claritin should also be approached with great caution. The active substance of the drug freely penetrates into breast milk. The concentration of the active component in breast milk can have exactly the same strength as in the woman’s circulatory system. If there is a need for a course of treatment with Claritin, it is best to stop breastfeeding and feed the baby with special formulas.

Both syrup and Claritin tablets are taken orally at any time, regardless of meals.

Side effects

It is very important to know not only how to take Claritin, but also what negative aspects this medication has. First of all, it should be noted that the symptoms of side effects in children and adults differ. Thus, while taking Claritin in childhood, symptoms such as migraine attacks, dullness of reaction and irritability may appear.

In adults, a slightly different clinical picture is observed. Thus, taking the drug can provoke fatigue, a feeling of drowsiness and dry mouth, attacks of nausea and tachycardia. In ten percent of cases, taking medication can cause problems with liver function, gastritis and baldness.

Generics

Claritin analogues are divided into two categories. The first category includes those medicines that contain the same active substance. The second category of drug may have a different composition, but a similar therapeutic effect.
  1. The drugs of the first group include such medications as: Alerpriv, Lomilan, Clargotil, Clarifer, Loratadine, Lotharen and Erolin.
  2. Drugs in the second category include Zodak, Diazolin, Kestin, Ketotifen, Suprastin, Erius, Telfast and Dinox.

Comparison with other popular medicines

Claritin, Tavegil, Suprastin

Drugs such as Tavegil and Suprastin have a complex effect on the body and are endowed with an impressive list of side effects. In addition, these therapeutic agents have a huge effect on the mucous membrane of internal organs and the central nervous system. In comparison with them, Claritin acts more selectively and affects only those receptors that are responsible for the allergic reaction. This property of the medication allows you to avoid problems with the gastrointestinal tract and central nervous system.

In addition, taking Claritin is not accompanied by a feeling of drowsiness. In contrast, the action of Suprastin and Tavegil leads to inhibition of the central nervous system. Another negative nuance associated with these drugs is that their action leads to dryness of the mucous membranes of the nasopharynx, which causes increased mucus formation. Dry mucous membranes are ideal conditions for the growth of bacteria and various infections. Claritin does not demonstrate a similar effect, which helps reduce the risk of infection to a minimum.

Considering the advantages and disadvantages of these drugs, we can say that Claritin is a more modern medicine with less pronounced side effects. Of course, this does not mean that Suprastin or Tavegil are less effective medications, but upon closer examination they have a large number of disadvantages.

Claritin in other forms (ointments, drops) is currently not produced by any official pharmacological companies

Claritin and Erius

These medications are often compared, as they represent the latest generation of drugs to combat allergic reactions of the body. Each of the medications has an equal strength of therapeutic effect and a minimum number of side effects.

At first glance, the difference between these drugs lies only in their composition.

Experts talk about the possibility of replacing one medication with another, in the presence of certain factors, including increased sensitivity of the body to individual components. In addition, we should not forget about the individuality of each organism. There are cases when taking Claritin helps get rid of allergy symptoms that Erius could not cope with.

The only difference between these medications is that Erius is able to eliminate allergic cough, which Claritin cannot cope with.

In conclusion of the article, I would like to pay attention to how much Claritin costs. Thus, the average price in Russia ranges from two hundred to six hundred and fifty rubles, depending on the number of tablets in the package. The average price of syrup is three hundred rubles per bottle of sixty milliliters, and four hundred and fifty for one hundred and twenty milliliters.

Source: http://lechimkozhy.ru/preparaty/tabletki/ot-chego-pomogaet-klaritin.html

Allergy tablets Claritin

Claritin belongs to the group of new generation antihistamines; the drug has no side sedative effects or toxic effects on the cardiovascular system.

As an antiallergic drug, Claritin eases the course of allergies and alleviates its symptoms. When undergoing treatment courses during the seasonal period, it helps to get rid of the manifestations of hay fever and hay fever.

During allergy attacks, the use of Claritin eliminates the manifestations of bronchial asthma, allergic rhinitis, conjunctivitis, and prevents the development of anaphylactic reactions.

Effect of Claritin on the body

Allergy tablets Claritin are used where there is an inflammatory process. Taking the drug helps to quickly relieve exacerbations of diseases such as bronchial asthma and atopic dermatitis.

The action of Claritin is based on a selective effect on histamine receptors, when their work slows down, less histamine enters the blood and allergy symptoms subside.

The drug has antiexudative, antiallergic, anti-inflammatory and antipruritic effects

Claritidine is a fast-acting drug; literally minutes after taking Claritin allergy pills, a sick person begins to feel its effect, which lasts for 24 hours.

Release form

Allergy tablets Claritin are produced by the pharmaceutical corporation SCHERING-PLOUGH LABO. Claritin tablets have an oval, somewhat elongated shape and a line on the surface. White tablets, the main active ingredient is Loratadine in a dosage of 10 mg, as well as excipients with hypoallergenic properties.

Indications for use of Claritin

Allergy tablets Claritin are used for their direct use, namely to relieve symptoms of seasonal and year-round runny nose, allergic conjunctivitis, hay fever, hay fever, bronchial asthma, dermatoses (atopic dermatitis, urticaria, eczema), Quincke's edema,

Claritin works well and quickly for food allergies and allergies to insect bites, relieves symptoms such as skin rashes, sneezing, lacrimation, bronchospasm and itching.

Instructions for use of Claritin

Claritin allergy tablets are taken in a dose of 10 mg once a day with plain water, regardless of meal time. For liver pathology and children from 2 to 6 years old, half the dose is recommended, that is, 5 mg.

When performing skin tests or blood tests for immunoglobulins, you should stop taking Claritin allergy tablets two days before the tests to get reliable results.

An overdose of Claritin is possible when more than 40 mg of the substance is ingested. In this case, extrapyramidal symptoms and palpitations are detected. In this case, gastric lavage and the administration of sorbents - activated carbon, Enterosgel and other drugs - are used.

Allergy tablets Claritin are used for both therapeutic and preventive purposes. For treatment, the drug is used in courses lasting up to two weeks.

For preventive purposes, Claritin allergy pills can be taken for a longer period of time, especially during the dusting season or shortly before the expected exacerbation.

Contraindications for the use of Claritin

Take Claritin tablets with caution during pregnancy and lactation: only when this use is justified, although numerous studies have not revealed any negative effects on the fetus.

When breastfeeding a child, you should avoid taking Claritin, or transfer the child to artificial feeding if it is necessary for a woman to take Claritin.

Side effects of Claritin include dizziness, headache, some lethargy, and fatigue. These manifestations occur rarely.

So, Claritin allergy tablets, unlike other antihistamines, have a selective effect on histamine receptors, perfectly relieve allergy symptoms and have a minimum of side effects. It is better to entrust the choice of antihistamines to an allergist, who will always recommend the best remedy to preserve your health.

Source: http://www.iallergy.ru/tabletki-ot-allergii-klaritin/

Claritin how much to take

How many days should I take Claritin?

Report a violation

The instructions for use of Claritin do not contain precise information on the duration of one course of treatment. The duration of taking the drug is determined individually by an allergist; the usual course is from 3 to 10 days in case of severe exacerbation of allergies. For chronic allergic diseases, Claritin is taken for a course of 3 to 12 months, again as prescribed by a doctor.

Report a violation

Tablets Claritin No. 10 cost, Claritin No. 7 cost, Claritin No. 30 cost.

Report a violation

You can take the antiallergic drug Claritin throughout the day. For allergic seasonal rhinitis, the course can be increased to 28 days.

Claritin for children

Allergic reactions of the child's body, in addition to skin rashes, are often accompanied by rhinitis. A stuffy nose prevents the child from breathing fully, and the skin rash causes itching. To eliminate these uncomfortable manifestations of allergies, as well as to prevent them from causing complications in the form of more severe diseases, such as bronchial asthma, experts prescribe antihistamines to children. Among them is claritin, which we will discuss in more detail below.

Composition and release form of Claritin

The main active ingredient of Claritin is loratadine. The anti-allergy drug Claritin is sold in pharmacies in the form of tablets or syrup. The tablets contain lactose and corn starch as additional substances.

To GET RID of allergies, Elena Malysheva recommends a new method based on a folk recipe from the 17th century.

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Claritin syrup for children is a colorless liquid, sometimes with a yellowish tint. Due to the presence of flavoring and sucrose, it is sweet with a peach flavor, so children take it with pleasure.

When should you take Claritin?

Claritin is prescribed to children with the appearance of hives and an allergic reaction after an insect bite. The drug is also effective for children suffering from a hereditary predisposition to allergies or neurodermatitis.

The indication for the use of children's Claritin is allergic rhinitis. The drug effectively relieves the symptoms of a runny nose, relieving nasal congestion, itching, eliminating sneezing and burning eyes.

Based on the picture of the disease, specialists can prescribe the drug to children during the acute period of an infectious-inflammatory disease. By relieving tissue swelling, Claritin prevents the development of an allergic reaction in a sick child.

Claritin begins to have an antihistamine effect on the body 1 to 3 hours after taking the drug. Within 24 hours, it relieves tissue swelling and eliminates itching.

Claritin is taken once a day, regardless of the child’s food intake.

Syrup. The daily dose of syrup for children from 2 to 12 years old is 5 ml. If the child’s body weight exceeds 30 kg, the dosage of syrup is increased exactly twice. For children over 12 years of age, Claritin is prescribed in a dosage of 10 ml per day.

Pills. If the child does not refuse to take the tablets, then they are given half a tablet once a day to children from 2 to 12 years old. Children over 12 years of age and children whose body weight is more than 30 kg are prescribed one Claritin tablet per day.

Children suffering from impaired renal or liver function are recommended to take 10 ml of syrup or 1 tablet of Claritin once every two days.

How long can you take Claritin?

The duration of taking Claritin should be determined by a specialist.

In clinical settings, a persistent effect of claritin, without side effects, was observed for 28 days.

Contraindications to the use of Claritin

Children under 2 years of age should not take Claritin.

A contraindication to the use of the drug is intolerance to the components included in its composition. Children with kidney or liver failure can take Claritin under the supervision of a specialist.

Side effects of Claritin

In children, side effects while taking Claritin are extremely rare. Their main manifestations are:

In recommended doses, Claritin does not cause an overdose. If the medication is taken above the recommended dose, dizziness, drowsiness and rapid heartbeat may occur, and less commonly, tachycardia.

In case of an overdose, a child must undergo gastric lavage and show it to a specialist who will prescribe maintenance therapy.

Claritin

Content

Pharmacological properties of the drug Claritin

Pharmacodynamics. Claritin is an antihistamine, a selective blocker of peripheral H1-histamine receptors. Clinical studies have shown that improvement in the condition of most patients began within the first 30 minutes of using Claritin. The antiallergic effect develops during the first 30 minutes after taking the drug, reaches a maximum within 8–12 hours and lasts 24 hours. Loratadine and its metabolites do not penetrate the BBB. Claritin does not affect the central nervous system, does not exhibit anticholinergic or sedative effects, and does not affect the speed of psychomotor reactions. In a clinical study in which Claritin was used for 90 days at a dose that was 4 times higher than the therapeutic dose, no clinically significant prolongation of the QT interval was detected on the ECG.

Pharmacokinetics. Claritin is rapidly absorbed into the gastrointestinal tract. The time to reach the maximum concentration of loratadine in the blood plasma is 1–1.3 hours, and the time to reach the maximum concentration of the main metabolite, desloratadine, is approximately 2.5 hours. Eating increases the time to reach the maximum concentration of loratadine and desloratadine by 1 hour. The maximum concentration of loratadine and desloratadine is not affected by food intake. The maximum concentration increases in elderly patients, patients with chronic renal failure or alcoholic liver damage.

In almost all cases, the level of influence of metabolites is higher than the level of influence of the parent substance. Determinable concentrations appear in the blood plasma within 15 minutes after taking the drug orally. A comparative study of the use of Claritin syrup and tablets in adequate doses showed that the plasma concentration profile of desloratadine for both dosage forms is comparable.

An in vitro study of human liver microsomes revealed that loratadine is metabolized to desloratadine mainly under the influence of cytochrome P450 3A4 (CYP 3A4) and to a lesser extent cytochrome P450 2D6 (CYP 3D6). The half-life is 8.4 hours for loratadine, 28 hours for its metabolites. About 27% of the administered dose is excreted in the urine during the first 24 hours. In the presence of ketoconazole, a CYP3A4 inhibitor, loratadine is converted to desloratadine primarily by CYP3D6. The half-life increases with alcoholic liver damage and does not change in the presence of chronic renal failure.

The pharmacokinetics of Claritin in children aged 1–2 years when prescribed a single dose of 2.5 mg does not differ from those in adults and older children.

Indications for use of the drug Claritin

Seasonal (polynosis) and year-round allergic rhinitis and allergic conjunctivitis - elimination of symptoms associated with these diseases: sneezing, itching of the nasal mucosa, rhinorrhea, burning sensation and itching of the eyes, lacrimation. Chronic idiopathic urticaria. Skin diseases of allergic origin.

Use of the drug Claritin

Adults and children ≥12 years old - 10 mg (1 tablet) 1 time per day;

children aged 2–12 years with a body weight of 30 kg - 10 mg (1 tablet) 1 time per day, with a body weight ≤30 kg - 5 mg (1/2 t tablet) 1 time per day;

children aged 1–2 years - 2.5 mg (1/4 t tablet) Claritin 1 time per day.

Adults and children aged ≥12 years - 10 mg (2 scoops - 10 ml syrup) 1 time per day;

children aged 2–12 years with body weight ≥30 kg - 10 mg (2 measuring spoons - 10 ml of syrup) 1 time per day, ≤30 kg - 5 mg (1 measuring spoon - 5 ml of syrup) 1 time per day;

children aged 1–2 years - 2.5 mg (1/2 measuring spoon - 2.5 ml of syrup) 1 time per day.

Contraindications to the use of the drug Claritin

Hypersensitivity (or idiosyncrasy) to any of the components of the drug.

Side effects of the drug Claritin

The incidence of side effects with Claritin is approximately the same as with placebo. Side effects such as fatigue, headache, drowsiness, dry mouth, gastrointestinal disorders (nausea, gastritis), allergic rash were noted. During the studies, isolated cases of alopecia, anaphylaxis, liver dysfunction, tachycardia and palpitations were observed.

Special instructions for the use of Claritin

Claritin does not have a clinically significant sedative effect when used in recommended doses (10 mg once daily). Claritin does not potentiate the effects of alcohol. At recommended doses, it does not affect the ability to drive vehicles or operate complex machinery.

Claritin should be discontinued at least 48 hours before skin diagnostic allergy tests are performed to prevent false results.

For patients with severe liver dysfunction, the initial dose should be reduced due to a possible decrease in the clearance of loratadine (an initial dose of 5 mg once daily or 10 mg every other day is recommended).

Use in children. The effectiveness and safety of Claritin in children under 1 year of age has not been proven. It should be noted that the pharmacokinetics of Claritin in children aged 1–2 years when prescribed a single dose of 2.5 mg does not differ from the pharmacokinetics of adults and older children.

Use during pregnancy and lactation. The safety of using the drug during pregnancy has not been established, therefore Claritin should be used only if the benefits of its use for the mother outweigh the potential risk to the fetus. Since loratadine is excreted in breast milk, a choice must be made between taking the drug and breastfeeding.

Drug interactions Claritin

When loratadine was taken simultaneously with ketoconazole, erythromycin, cimetidine, an increase in the concentration of loratadine in the blood plasma was noted, but this increase did not manifest itself clinically, including according to ECG data.

Claritin overdose, symptoms and treatment

In case of overdose, drowsiness, tachycardia and headache may occur. With a single dose of 160 mg, no side effects were noted (including ECG changes). In case of overdose, symptomatic and supportive treatment is recommended. Standard measures are recommended to remove unabsorbed drug from the stomach: gastric lavage, taking activated charcoal. Loratadine is not eliminated by hemodialysis. After emergency treatment, the patient should remain under medical supervision.

Storage conditions for the drug Claritin

In a dry place at a temperature not exceeding 25 °C.

Source: http://stop-allergies.ru/klaritin-skolko-prinimat/