Tizin: drops and spray for sinusitis
An effective remedy - Tizin Xylo nasal drops - is xylometazoline, which is an alpha-agonist. The active ingredient Tizin activates adrenaline receptors.
Table of contents:
- Tizin: drops and spray for sinusitis
- Effect of the drug
- Forms of release of the drug
- Use of the drug
- General Application
- Use for sinusitis
- Contraindications and side effects
- Tizin
- Composition of Tizin
- Release form
- pharmachologic effect
- Pharmacodynamics and pharmacokinetics
- Indications for use
- Contraindications for Tizin
- Side effects
- Instructions for use of Tizin (Method and dosage)
- Overdose
- Interaction
- Terms of sale
- Storage conditions
- Best before date
- special instructions
- Tizin's analogs
- Tizin during pregnancy and lactation
- Tizin for children
- Reviews about Tizin
- Tizin price, where to buy
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- Tizin - instructions for use, reviews, analogs and release forms (nasal drops 0.1%, nasal spray 0.05% and 0.1% Xylo and Xylo Bio) medications for the treatment of runny nose in adults, children and pregnancy. Compound
- Tizin Xylo - vasoconstrictor drops for runny nose, rhinitis, sinusitis and sinusitis.
- Composition and pharmacological action of Tizin Xylo
- Spray Tizin
- Nasal drops
- Tizin Xylo and indications for use
- Orientation, side effects and overdose
- Restrictions and contraindications for the use of Tizin during pregnancy and in some other cases
- Interaction of Tizin with other drugs
- Price category, holiday conditions and storage
- Price range
- Vasoconstrictor drug Tizin: release forms and instructions for use
- Compound
- Effect of the drug
- Dosage forms
- Indications
- Contraindications
- Instructions
- Tizin Bio
- Tizin Allergo
- Tizin for children
- Tizin for pregnant women
- Side effects
- Overdose
- Analogs
- Dosage and instructions for use of children's Tizin against runny nose and nasal congestion
- Pharmacological properties
- Release form and composition of the drug
- Indications for use
- Contraindications
- Possible side effects
- Instructions for use and dosage
- Cost and storage conditions
- Analogs of a medicinal product
Due to this, a persistent therapeutic effect is observed during use of the drug. Tizin nasal drops are prescribed to both adults and children starting from 2 years old.
Effect of the drug
This drug is used for various acute and chronic respiratory diseases. Tizin treats sinusitis, rhinitis (both allergic and vasomotor), sinusitis, hay fever. The therapeutic agent also serves to prepare patients for diagnostic manipulations in the nasal passages. In particular, it is used before puncture of the sinuses for sinusitis.
After instilling or injecting the medicine into the nasal cavity, Tizin begins to act literally within 5–10 minutes. It is very good at reducing swelling of the nasal mucosa. The drug has a rapid and persistent (within several hours) vasoconstrictor effect. The use of Tizin significantly facilitates nasal breathing and improves the removal of secretions from the nasal cavity.
Pediatricians quite often use Tizin nasal drops for children in the treatment of otitis media. The reason for using the drug for this purpose is simple and justified by physiology. Children have wide and short passages connecting the middle ear cavity and the maxillary sinuses. The injected drug penetrates directly to the source of inflammation, reducing swelling and alleviating the child’s condition.
Forms of release of the drug
Tizin Xylo is available in various forms and dosages of the active substance xylometazoline, namely:
- nasal drops at a concentration of 0.05%;
- nasal drops 0.1%;
- nasal spray 0.05%;
- nasal spray 0.1%.
The drug with a lower percentage dosage is intended for the treatment of diseases in children aged 2 to 6 years.
Use of the drug
When using Tizin cold spray, it should be taken into account that long-term use of the medicine can cause atrophy of the mucous membrane of the nasal passages. The swelling of this tissue can take a chronic form, in which vasoconstrictor drops will have to be used constantly. Therefore, therapy is recommended to be carried out as prescribed by a doctor. Strict adherence to the recommendations and dosage will allow you to effectively cure the disease.
For long-term therapy, it is recommended to use Tizin in gel form. This type of medicine does not dry out the nasal mucosa and does not irritate it. However, the administration of the drug in this form is contraindicated for children under 7 years of age.
General Application
The duration of use of the drug and its dosage depend on the severity of the disease.
When prescribing therapy, the patient's age and individual sensitivity to the drug are also taken into account. Regardless of the chosen treatment regimen, you should not use Tizin for more than 5 days.
As a rule, its use for colds involves treating the nasal passages 3, maximum 4 times a day.
Use for sinusitis
Tizin Xylo for sinusitis effectively alleviates the patient’s condition, relieves swelling of the mucous membrane and restores nasal breathing. Different forms of release determine special treatment regimens:
- spray 0.05% is used for children under 6 years of age, one injection into the nasal passages no more than 2 times a day;
- spray 0.1% is used for children over 6 years of age, as well as for adults - in each nasal passage up to 3 times a day;
- nasal drops - one drop in each nostril maximum 3 times a day if the patient’s age is from 6 to 12 years;
- for patients with sinusitis over 12 years of age, the dosage is increased to 2 drops into the nasal passage, also three times a day.
If there is a need to use Tizin nasal spray for repeated therapy, then it is necessary to maintain an interval between courses of administration. As a rule, such a break should be several days.
When used correctly, Tizin in dosage for children is effective and safe. This allows it to be widely used even in the treatment of two-year-old children.
Contraindications and side effects
The drug is contraindicated in patients with atherosclerosis, atrophic rhinitis, and glaucoma. Do not use Tizin nasal spray for tachycardia and individual intolerance. The medicine should not be used by pregnant women, as well as those people who have undergone neurosurgical operations. The simultaneous use of Tizin and drugs that increase blood pressure, as well as MAO inhibitors (monoamine oxidase) is not recommended.
Respiratory diseases can seriously impair the quality of life. To effectively combat them, restoring nasal breathing is extremely important. The use of Tizin as an adjuvant has proven itself in the treatment of sinusitis and other ENT diseases. The ability to use the drug for different age categories makes it very popular.
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Tizin
Description current as of 01/08/2015
- Latin name: Tyzine
- ATX code: R01AA06
- Active ingredient: Tetrizoline
- Manufacturer: Heinrich Mac Nasl. GmbH & Co. KG, Germany
Composition of Tizin
The composition of Tizin nasal drops differs in the concentration of the active drug compound, depending on the type of drug.
In 1 ml. nasal drops (concentration 0.1%) contains 1 mg. tetrizoline hydrochloride, and in addition, such auxiliary components as: perfume oil, benzalkonium chloride, benzyl alcohol, disodium edetate, hydrochloric acid, sodium citrate, sorbitol, polyoxyethylene glycerol trihydroxystearate 40, water, sorbitol and methylhydroxypropylcellulose.
In 1 ml. Children's Tizin (concentration 0.05%) also contains 1 mg. medicinal compound and auxiliary components similar to the form of the drug described above.
Release form
Nasal drops are an opalescent, colorless, transparent liquid, which is produced in specialized dropper bottles made of dark glass with a nominal volume of 10 ml. One package of Tizin contains only one bottle of nasal drops.
pharmachologic effect
Tizin belongs to a group of drugs that affect alpha-adrenergic receptors and have anti-edematous and vasoconstrictor properties.
Pharmacodynamics and pharmacokinetics
When using Tizin, drops narrow the small arterioles located in the nasal passages, while eliminating swelling of the mucous tissues and reducing secretion. As a rule, the effect of using the drug occurs within one minute after its use and lasts for a maximum of 8 hours. It is noteworthy that these nasal drops are almost not absorbed.
Indications for use
This drug is indicated for use for sinusitis, rhinitis, pharyngitis, as well as hay fever. In addition, Tizin nasal drops are used as a preparatory agent before diagnostic or therapeutic procedures to eliminate swelling of the mucous tissues of the nasal passages and nasopharynx.
Contraindications for Tizin
Contraindications to the use of the drug are angle-closure glaucoma, dry rhinitis, and hypersensitivity. It is worth remembering that there are age restrictions on these nasal drops. For the treatment of children under 2 years of age, the drug should not be used, the concentration of the active compound in which reaches 0.05%. For patients under 6 years of age, the “adult” form of Tizin is contraindicated, i.e. drops 0.1%.
This drug should be used with extreme caution in the treatment of patients suffering from diseases such as: ischemic heart disease, hypertension, aneurysm, arrhythmia, pheochromocytoma, diabetes, hyperthyroidism and some other cardiovascular and metabolic disorders.
Side effects
As a result of non-compliance with the recommendations for the use of the drug, side effects may occur such as: burning, hyperemia, with prolonged use, swelling of the mucous tissues of the nasal passages, tremor, palpitation, sweating, headaches, weakness and surges in blood pressure.
Instructions for use of Tizin (Method and dosage)
According to the instructions for Tizin, nasal drops are used intranasally, i.e. instilled into the nasal passages with the head slightly tilted back. For adult patients and children over the age of 6 years, it is recommended to instill 2 or 4 drops of the drug, with a concentration of 0.1%, into each nostril.
Children's Tizin, with a concentration of 0.05%, is used in the treatment of children aged 2 to 6 years in a dosage equal to 2-3 drops. During pregnancy, Tizin is used if the expected benefit is significantly greater than the harm. Nasal drops should be used no more than once every 4 hours.
As a rule, the drug has a long-lasting effect, so it is enough to use it infrequently. It should be remembered that the maximum duration of treatment with the drug should not exceed 5 days for adult patients and 3 days for children.
Although the use of drops before bed is considered an effective measure for eliminating nasal congestion throughout the night, the drug can cause insomnia because it affects the human nervous system.
A second course of treatment with Tizin can be prescribed several days after the previous therapeutic treatment.
Overdose
In case of an overdose of Tizin, symptoms such as cyanosis, dilated pupils, convulsions, nausea, fever, arrhythmia, hypertension, tachycardia, pulmonary edema, mental and respiratory disorders, cardiac arrest appear.
Interaction
Tizin should not be used in conjunction with tricyclic antidepressants, as well as with monoamine oxidase inhibitors, since such a combination can have a vasoconstrictor effect on the human body, and, in addition, affect blood pressure levels.
Terms of sale
These nasal drops can be purchased at a pharmacy without a doctor's prescription.
Storage conditions
Tizin should be stored out of the reach of children at a temperature not exceeding 25 C.
Best before date
special instructions
Since this drug can cause the development of visual impairment, during its use you should refrain from activities that require concentration and reaction speed, for example, driving a car or working with units and mechanisms that are potentially dangerous to life and health.
Tizin's analogs
The main analogues of Tizin nasal drops include Vizin, Montevisin, Tetrizolin, VizOptic, Berberyl, and Octilia.
Tizin during pregnancy and lactation
Many women wonder whether Tizin can be used as nasal drops during pregnancy and breastfeeding. In accordance with the instructions, the drug can be used by pregnant and nursing mothers only if the expected benefit is significantly higher than the possible harm.
Many believe that children's Tizin can be used without fear during pregnancy and lactation, but this is not the case, since when using both forms of the drug, life-threatening vasoconstrictor side effects can occur for both the mother and the child.
Tizin for children
For children, these nasal drops are not contraindicated, provided all recommendations are followed. Reviews of children's nasal drops are mostly positive. The average price of this type of medicine, as a rule, does not exceed 110 rubles.
Reviews about Tizin
Patients using this drug usually leave positive reviews about Tizin, both for children and adults of the nasal drops variety. Many parents note the effectiveness of the drug for children.
Tizin price, where to buy
The price of Tizin depends, first of all, on the type of drug (for children or adults). The average price of Tizin nasal drops varies from 90 to 120 rubles.
The children's drug costs approximately rubles.
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The drops are good, but they give me a severe allergic nasal discharge. If there is nothing else in the house except tizin, then I use it with antiallergic drugs
Gray: Tablets are effective, I didn’t think that only tablets would help me restore my .
Amina: Until recently, I was afraid to take glycine, because I thought that there would be an excess in the body.
Sivaya: I started taking ginkum before the session because I was very worried that I wouldn’t have time to do everything.
Igor: it helps, try it, I wanted de-nol, but it’s easier
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Tizin - instructions for use, reviews, analogs and release forms (nasal drops 0.1%, nasal spray 0.05% and 0.1% Xylo and Xylo Bio) medications for the treatment of runny nose in adults, children and pregnancy. Compound
In this article you can read the instructions for use of the drug Tizin. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Tizin in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Tizin analogues in the presence of existing structural analogues. Use for the treatment of runny nose in adults, children, as well as during pregnancy and breastfeeding. Composition of the drug.
Tizin is a sympathomimetic. When applied topically, it causes a vasoconstrictor effect that develops within a few minutes and persists for a long time.
Tizin Xylo Bio is a vasoconstrictor drug for topical use in ENT practice. Xylometazoline (imidazole derivative) is an alpha-adrenergic agonist that constricts the blood vessels of the nasal mucosa, eliminating swelling and hyperemia of the mucous membrane. Facilitates nasal breathing during rhinitis. Hyaluronic acid, which is part of the drug, has a moisturizing effect when used in nasal medications due to its ability to maintain mucous membranes in a hydrated state and creates optimal conditions for regenerative processes.
The action usually develops within 5-10 minutes.
Tetrizoline + excipients (Tizin).
Xylometazoline hydrochloride + excipients (Xylo and Xylo Bio).
When applied topically, systemic absorption is low.
- minor eye irritation;
- itching, swelling and hyperemia of the conjunctiva;
- burning, lacrimation, scleral injection caused by chemical and physical factors (dust, cosmetics, swimming in chlorinated water, exposure to bright light);
- allergic conjunctivitis;
- to reduce swelling of the mucous membrane of the nasopharynx and discharge in acute allergic rhinitis, acute respiratory infections with rhinitis, sinusitis, hay fever, otitis media;
- preparing patients for diagnostic manipulations in the nasal passages.
Nasal spray 0.05% and 0.1% (Tizin Xylo and Xylo Bio).
Instructions for use and method of use
Tizin Xylo and Bio in the form of a nasal spray 0.05% are prescribed to children aged 2 to 6 years, 1 dose in each nasal passage 1-2 times a day.
Tizin Xylo and Bio in the form of a nasal spray 0.1% are prescribed to adults and children over 6 years of age, 1 dose in each nasal passage 3 times a day.
The dose depends on the individual sensitivity of the patient and the clinical effect.
You should not use the drug for more than 5-7 days without a doctor’s recommendation.
After completion of therapy, the drug can be re-administered only after a few days.
The duration of use of the drug in children is determined by the doctor.
Rules for using the drug
Remove the protective cap. Before first use, press the spray nozzle several times until a uniform cloud of “fog” appears. The bottle is ready for use. When using, press 1 time. Inhale the drug through the nose. If possible, keep the spray bottle vertical. Do not spray horizontally or downwards. After use, the bottle should be closed with a cap.
- transient mild nasal irritation (burning) in susceptible people;
- sneeze;
- increased swelling of the nasal mucosa (reactive hyperemia);
- headache;
- insomnia;
- visual impairment;
- fatigue and depression (with long-term use in high doses);
- heartbeat;
- tachycardia;
- arrhythmia;
- increase in blood pressure.
- simultaneous use of MAO inhibitors or other drugs that increase blood pressure;
- tachycardia;
- glaucoma;
- atrophic rhinitis;
- surgical interventions on the meninges (history);
- thyrotoxicosis;
- patients with severe cardiovascular diseases (for example, coronary artery disease (including angina), tachycardia, arterial hypertension, severe atherosclerosis);
- patients with a history of surgical interventions on the meninges;
- children under 6 years of age (for nasal spray 0.1%);
- children under 2 years of age (for nasal spray 0.05%);
- hypersensitivity to any of the components of the drug.
Use during pregnancy and breastfeeding
Xylometazoline should not be used during pregnancy, because the effect on the fetus has not been studied in clinical studies.
The drug should not be used during breastfeeding, because It is unknown whether the active substance is excreted in breast milk.
Long-term use and overdose of sympathomimetics that have a decongestant effect can lead to reactive hyperemia of the nasal mucosa. As a result, difficulty in nasal breathing occurs, which leads to the patient starting to use the drug repeatedly or even constantly. This can lead to chronic swelling (medicinal rhinitis), and eventually even to atrophy of the nasal mucosa (ozena).
In milder cases, to improve the patient's condition, you can first stop administering the sympathomimetic in one nasal passage, and after the complaints have subsided, continue to administer it into the other nasal passage to partially ensure nasal breathing.
The patient should be informed that if the medicine has become unusable or has expired, it should not be thrown into wastewater or onto the street. It is necessary to place the medicine in a bag and place it in the trash container. These measures will help protect the environment.
Impact on the ability to drive vehicles and operate machinery
With long-term treatment or use of the drug in higher doses, the possibility of its systemic effect on the cardiovascular system cannot be excluded. In such cases, the ability to drive and use machinery may be impaired.
Concomitant use of MAO inhibitors such as tranylcypromine or tricyclic antidepressants may lead to an increase in blood pressure due to the cardiovascular effects of these substances.
Structural analogues of the active substance:
Analogs for therapeutic effect (drugs for the treatment of runny nose):
Tizin Xylo - vasoconstrictor drops for runny nose, rhinitis, sinusitis and sinusitis.
Acute and chronic runny nose, as well as their complications in the form of sinusitis of various localizations (sinusitis and frontal sinusitis), with a prolonged course, sharply worsen a person’s quality of life and can be accompanied by otitis, laryngitis and bronchitis, as well as inflammatory processes of the brain and its membranes. With reduced immunity, these diseases become recurrent and difficult to treat with conventional methods.
Before you continue reading: If you are looking for an effective method of getting rid of a runny nose, pharyngitis, tonsillitis, bronchitis or colds, then be sure to look at this section of the site after reading this article. This information has helped so many people, we hope it will help you too! So, now back to the article.
One of the most effective and safe medications - Tizin Xylo (spray or nasal drops) - a drug from the group of alpha-adrenergic stimulants, helps to get rid of the disease and prevent complications. Alpha adrenergic stimulants are substances that increase the activity of adrenaline receptors. As a result, characteristic effects are observed: in particular, the tone of smooth muscles increases, including the muscles of the walls of blood vessels, while they spasm.
Due to the activation of adrenergic receptors, Tizin drops have a pronounced therapeutic effect for rhinitis (as a runny nose is called in medical terminology), including its allergic forms, accompanied by swelling of the nasopharyngeal mucosa and difficulty breathing. The latter conditions are extremely difficult to tolerate and, as a rule, are protracted.
According to the instructions, Tizin Xylo can be used to treat adults and children, starting from infancy. The spray and drops are low-toxic, and their therapeutic effect is fast and lasting. Compared to nasal drops of the previous generation, this medicine wins in all respects. The best evidence of the effectiveness of Tizin is patient reviews and enormous popularity among doctors of various specializations: therapists, pediatricians, allergists and otorhinolaryngologists.
Tizin Xylo for infants and older children varies in concentration, which should always be indicated in the price list along with the price of the drug. Tizin for children under 7 years of age is produced in a lower percentage dosage, so when purchasing you should pay special attention to this indicator.
Composition and pharmacological action of Tizin Xylo
The pharmacological action of the drug Tizin in the instructions for use is explained by its chemical structure and group affiliation.
The active substance - tetrizoline hydrochloride - belongs to alpha-adrenergic stimulants and provides a rapid and lasting vasoconstrictor effect. As a result, instillation or injection of the drug into the nasal cavity leads to a reduction in swelling of the mucous membrane, freeing up the nasal passages and normalizing breathing. Both spray and Tizin drops act almost instantly, and the resulting effect lasts for several hours. Like all long-term nasal medications, this drug contains excipients - preservatives, etc. As such, benzalkonium chloride, benzyl alcohol and disodium edetate are added to the composition.
Spray Tizin
A nasal spray is a liquid dosage form that is administered into the nasal sinuses using a special dispenser. Like other nasal sprays, Tizin spray is available in a bottle with a spray dispenser. Prescribed for children over 6 years of age and adults. It has a quick and lasting effect and is used for treatment and diagnosis. For children in this form the drug is available as a 0.05% solution, for adults – 0.1%.
It should be remembered that Tizin in the form of a spray should not be used for a long time, or more often than indicated in the instructions or recommended by a doctor. Otherwise, especially with long-term use, the development of side effects is possible (see below). Usually the spray is prescribed in short courses, no more than 4 times a day (one injection into each nasal passage). If for some reason long-term therapy is necessary, for older children and adults it is recommended to use the drug in the form of a gel (such Tizin also exists): it irritates the mucous membrane less and does not lead to drying out.
Nasal drops
Tizin nasal drops, like the medicine in the form of a spray, are available for adults and children in dosages similar to those indicated above, in bottles with a special dropper. For young children, nasal drops are easier and safer than using a spray or gel. Therefore, the drug is prescribed to children under 6 years of age in drops, 1-2 in each nasal passage, no more than three times a day. The medicine is not indicated for long-term use in young children. If treatment is delayed, the drops are replaced with gel (for older children and adults).
Tizin Xylo and indications for use
The highly effective and low-toxicity Tizin Xylo can be prescribed both for the treatment of a number of diseases and for preparing the patient for diagnostic studies involving certain medical manipulations in the nasal cavity.
Allergists everywhere prescribe Tizin for the treatment of acute rhinitis of allergic origin. The medicine is also widely used for acute respiratory infections accompanied by a runny nose. The pediatric form of the drug is indicated for otitis media. In this case, its use helps not only to reduce swelling of the nasopharyngeal mucosa: in children, the passages between the maxillary sinuses and the middle ear cavity are short and wide, and therefore Tizin Xylo penetrates directly to the site of inflammation, relieving swelling and relieving pressure on the eardrum.
Tizin is also recommended for preparing adult patients with suspected sinusitis or an established diagnosis for therapeutic and diagnostic puncture of the maxillary sinus: reducing swelling allows the doctor to easily insert the necessary instruments into the nasal passage.
In addition, Tizin is used for children in the treatment of various hay fever. At the same time, it allows you to significantly reduce the duration of therapy and significantly improves the standard of living of patients. The drug is recommended not only as a means for premedication preparation for surgery, but also for drug therapy of sinusitis or sinusitis of other localization.
Orientation, side effects and overdose
Depending on the dosage form and dosage of Tizin Xylo, the price may vary slightly. Although some prefer to choose the most cost-effective option, when purchasing drops or spray, you need to focus not on the price, but on the diagnosis (ARD or acute allergic rhinitis, sinusitis, otitis media, etc.) and the age of the patient.
When used according to instructions, Tizin has virtually no adverse reactions. The main thing is to strictly follow the treatment regimen and its duration. The high effectiveness of the drug allows you not to think about the duration of treatment for uncomplicated acute respiratory infections. However, the effect in the treatment of persistent hay fever and sinusitis may not be so quick.
If the recommended duration of therapy and the frequency of instillation/injection are exceeded, Tizin can cause irritation of the nasal mucosa: it becomes excessively dry, resulting in injury due to high/low temperatures, mechanical and other effects. In this case, patients experience burning and tingling in the nasal cavity, they are bothered by sneezing, and increased secretion of fluid.
In rare cases and, above all, with an overdose of the drug, swelling of the nasal mucosa can progress, and the patient’s condition can worsen, accompanied by tachycardia, heart rhythm disturbances, and increased blood pressure.
According to reviews, patients who used Tizin uncontrollably were bothered by intoxication symptoms: headache, blurred vision, nausea and vomiting, insomnia. These phenomena did not require urgent measures and, as a rule, disappeared on their own when treatment was discontinued.
With long-term therapy in high dosages, Tizin can provoke the development of depression. Therefore, patients with a tendency towards depressive disorders should be prescribed this medicine with a certain degree of caution.
Restrictions and contraindications for the use of Tizin during pregnancy and in some other cases
The main problems when taking the medicine arise in patients who have not carefully read the instructions or who have not paid attention to the restrictions and contraindications.
Tizin Xylo is very popular among adult patients who have experienced the obvious benefits of the drug. The demand for medicine is especially high in the off-season, when unstable weather and an abundance of viruses lead to an increase in the incidence of acute respiratory infections.
If the rules of use are followed, children's Tizin is not only effective, but also safe, and therefore in half a percent concentration it is very often used in pediatrics, starting from infancy. Allergists universally recommend this medication for both adults and children during an exacerbation of seasonal runny nose - hay fever.
However, like all medicines, Tizin, including children's, has restrictions on its use, as well as contraindications that you should be aware of.
These include individual intolerance to any of the components of the drug and a tendency to tachycardia. In adults - a severe form of atherosclerosis, the presence of glaucoma or atrophic rhinitis.
Tizin is not prescribed during pregnancy, hyperthyroidism, or if there is a history of surgical neurosurgical interventions. These contraindications are typical for all alpha-agonists. It is the stimulation of alpha-adrenergic receptors that imposes restrictions on the prescription of this drug to pregnant women: the drug is not suitable for use during pregnancy due to its ability to increase the tone of the smooth muscle muscles of the uterus. At the same time, it contracts, which can lead to miscarriage. But even if a miscarriage does not occur, the embryo inside the uterus with increased tone suffers from hypoxia and may not develop properly. Therefore, Tizin Xylo is completely contraindicated during pregnancy in the first and second trimester.
But if necessary, it can be recommended to nursing mothers, albeit with a certain degree of caution, in low concentrations and always under the supervision of the child’s condition by a pediatrician.
Instead of Tizin Xylo, other modern drugs can be successfully used during pregnancy. This, first of all, includes medicines based on natural herbs, hypoallergenic and not having any negative effect on the mother and fetus. If absolutely necessary, Tizin during late pregnancy can be prescribed with great caution in the form of drops. In this case, you should use a pediatric dosage and concentration and constantly monitor the condition of the patient and the fetus.
If children's Tizin is prescribed to children under two years of age, the child's condition during treatment should also be assessed by the attending physician.
It is recommended to avoid using this medicine in gel form in children under 7 years of age.
Chronic rhinitis is not a contraindication for the use of Tizin, but in this case it cannot be used for a long time. If colds are accompanied by the formation of crusts in the nose, the instructions recommend replacing the spray with a gel.
Interaction of Tizin with other drugs
The medicine is well compatible with most oral medications, but there are some exceptions. According to the instructions, Tizin for adults and children cannot be used together with MAO inhibitors and drugs from a number of tricyclic antidepressants.
Price category, holiday conditions and storage
The cost of this drug allows it to be prescribed without regard to the material wealth of any family: also because the courses of treatment are short and the consumption of the drug is low. The price of Tizin may vary depending on the form, percentage of active ingredient and markups of intermediaries. Due to its low toxicity, you can buy the medicine without a doctor's prescription. The drug can be stored for up to 3 years at room temperature.
Price range
The average price for Tizin for children 0.05% is 70 - 95 rubles;
adult 0.1%, Tizin BIO SPRAY – 170 – 200 rubles.
The article above and comments written by readers are for informational purposes only and do not encourage self-medication. Consult a specialist regarding your own symptoms and illnesses. When taking any medicine, you should always use the instructions that come with the medicine and your doctor's advice as a guide.
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Vasoconstrictor drug Tizin: release forms and instructions for use
The therapeutic effect of Tizin drops occurs a couple of minutes after application and lasts for a long time - about 8 hours. The drug is popular in the treatment of pathologies of the ENT organs. The effect of the drug is due to the active substances included in its composition.
Compound
Tizin nasal drops contain tetrizoline hydrochloride as the active ingredient.
In 1 ml of product its volume is:
- 0.5 mg tetrazoline (or 0.5% solution for children);
- 1 mg (or 1% solution for adults).
Additional components of the medicine are benzyl alcohol, sorbitol, benzalkonium chloride, water and others.
Effect of the drug
Coming into contact with the mucous membrane of the nose and nasopharynx, the drops have an active symptomatic effect, successfully eliminating the symptoms of rhinitis. The drug works as an alpha-adrenergic agonist, simultaneously providing vasoconstrictor and decongestant effects. In a short period of time, a vasoconstrictor effect is achieved, which lasts up to 8 hours.
The composition of Tizin is highly effective not only for runny nose of bacterial and viral origin, but also for allergic ENT pathologies that are extremely uncomfortable for humans.
Treatment with the drug, according to the instructions, is acceptable for both adults and children, starting from an early age. Tizin nasal drops are a low-toxic drug, and the therapeutic effect they have will be immediate and lasting.
Dosage forms
The drug is available in the following concentrations:
- Nasal drops 0.1% volume 10 ml - for children over 6 years old and adults.
- Nasal drops 0.05% volume 10 ml - for children.
Indications
The instructions for use indicate that Tizin is prescribed for the following conditions and diseases:
The drug is also used during diagnostic and therapeutic procedures, if it is necessary to eliminate swelling of the nasopharynx and normalize nasal breathing. It is not recommended to use nasal drops for more than 5 days, otherwise the patient may experience atrophy of the nasal mucosa.
Contraindications
Contraindications to the use of Tizin are as follows:
- individual hypersensitivity;
- angle-closure glaucoma;
- dry form of rhinitis;
- simultaneous use of monoamine oxidase inhibitors.
There are also age-related contraindications:
- 0.05% the drug is not prescribed until the age of two;
- The 0.1% drug is not recommended for children under 6 years of age.
Tizin is prescribed with caution during breastfeeding, during pregnancy, for endocrine disorders, and diseases of the cardiovascular system. It is also recommended that people who drive vehicles and operate complex machinery be more careful.
Instructions
The drug is prescribed intranasally.
Tizin 0.1%, unless otherwise recommended by a doctor, is prescribed to adults and children over 6 years old, 2-4 drops in each nasal passage.
Tizin 0.05%, unless otherwise prescribed, is instilled in 2 drops for children from 2 to 6 years old.
The drug should be used strictly as needed, but not more than once every 4 hours. As a rule, these drops are used much less frequently, since their therapeutic effect lasts at least 8 hours. Using the product in the evening ensures a peaceful fall asleep and sleep throughout the night.
Tizin Bio
Tizin Bio is a vasoconstrictor used topically in otolaryngology.
The active ingredient of Tizin Bio is an alpha-adrenergic agonist - xylometazoline hydrochloride. Release form: spray. The drug narrows the blood vessels of the nasal mucosa, eliminates swelling and hyperemia, restoring nasal breathing during rhinitis.
Hyaluronic acid in Tizin Bio creates a feeling of hydration and helps speed up the process of restoration of mucous membranes damaged during the disease.
Tizin Allergo
Tizin Allegro is a topical antiallergic drug. The active component of the drug - levocabastine hydrochloride - has an effect on histamine receptor blockers.
After a short course of treatment with the drug, the patient’s signs of allergic rhinitis disappear: copious discharge from the nasal cavity and swelling of the nasopharynx disappear.
Indications for use of Tizin Allergo:
- allergic rhinitis;
- exacerbation of hay fever in the phase of rhinoconjunctival syndrome;
- allergic conjunctivitis.
Tizin for allergies is available in the form of a spray. The drug has a quick effect, eliminates the symptoms of allergic rhinitis and improves the patient’s quality of life.
Tizin for children
The drug 0.1% concentration cannot be used to treat children under 6 years of age.
The 0.05% solution is not recommended for use in children under 2 years of age.
Before using nasal drops, you should always consult your doctor.
Tizin for pregnant women
According to the instructions for use, Tizin drops or spray should be prescribed to expectant mothers with caution in cases where the use of this remedy simply cannot be avoided. But only a doctor can prescribe the drug, who will monitor the condition of the woman and fetus during the treatment process.
In other cases, Tizin is contraindicated for pregnant women, since there is no accurate information about the safety of treatment with this drug and its effect on the fetus.
If there is a need to use Tizin during lactation, then it is advisable to switch the baby to artificial formulas for the period of treatment.
Side effects
Side effects of Tizin and Tizin Bio include:
- from the nervous system - drowsiness, general weakness, dizziness, migraine, tremor, sleep disorders;
- from the heart and blood vessels - cardiac dysfunction, increased blood pressure;
- from the endocrine system - hyperglycemia;
- from the digestive system - nausea, heartburn;
- from the respiratory system - burning and dryness in the nasal cavity, sneezing, secondary swelling of the mucous membrane as a result of exceeding the dose of the drug or with prolonged use;
- from the organs of vision - increased intraocular pressure, dilation of the pupil.
Overdose
In case of an overdose of Tizin, the following symptoms may occur:
- nausea;
- dilated pupils;
- heart rhythm disorders;
- increased blood pressure;
- pulmonary edema;
- mental disorders;
- increased drowsiness;
- state of shock;
- respiratory arrest;
- coma.
The drug does not have an antidote. In case of overdose, Physostigmine, Activated carbon, symptomatic therapy, and, in extreme cases, gastric lavage and artificial oxygen supply are prescribed as first aid if anticholinergic symptoms occur.
Analogs
You can replace Tizin with the following drugs:
- Nazivin. A nasal agent of the alpha-adrenergic agonist group, widely used in ENT practice. Release form: spray or drops. The active ingredient is oxymetazoline hydrochloride, which has a vasoconstrictor and anti-edematous effect. Nazivin, as an analogue of Tizin, is prescribed for the treatment of acute, vasomotor and allergic rhinitis, eustachitis and otitis media.
- Xylene. A drug based on a vasoconstrictor component, used in otolaryngology to treat the common cold. Release form: spray and drops. The active ingredient is xylometazoline. The drug is prescribed for acute rhinitis, including allergic origin, sinusitis and otitis media.
Many patients do not take specialists’ recommendations seriously on how to take Tizin, exceeding the dosage of the drug or increasing the course of treatment. Doing this is highly undesirable due to the high risk of side effects.
Tizin, like any medication, contains chemicals to which, if their concentration is unjustifiably exceeded, the body can react unpredictably.
Source: http://moylor.ru/lekarstva/tizin-sprej-i-kapli/
Dosage and instructions for use of children's Tizin against runny nose and nasal congestion
Children are susceptible to various types of respiratory diseases. An important role is played by the choice of a product that copes with rhinitis, lacrimation of the eyes (for allergic reactions), which is necessarily suitable for children. One of these medications is Tizin Xylo Bio spray. This drug is approved for use by children after two years of age. Children can also be given regular Tizin for adults, but only after the age of six.
The drug has a number of advantages, is safe for young patients, and does not cause side effects. Young parents should carefully study the instructions for the product and follow them flawlessly. Consult your pediatrician first and find out all aspects of taking the medication.
Pharmacological properties
Tizin is a synthetic medicine aimed at treating eye diseases and ailments accompanied by swelling of the nasal mucosa. The drug is approved for use in infectious and allergic pathologies of the nasopharynx. The product has a vasoconstrictor, has an anti-congestive effect, constricts blood vessels in the nasal cavity, and facilitates nasal breathing during rhinitis.
After just a few minutes, the drug begins to act, the effect lasts up to 8 hours, which means less medication is taken. To obtain a long-term positive effect, Tizin is used systematically; with constant use, the medicine has a central sedative effect. That is why the medication continues to act at night, and repeated use becomes unnecessary. Select the right form of medication for your baby and begin the course of treatment immediately.
Release form and composition of the drug
Tizin is produced in the form of a nasal spray of a transparent color with a specific faint odor, available in 0.05% and 0.1%. Tizin drops are similar to a spray; they have only one type of dosage of the active component - 0.1%. The product is packaged in a plastic bottle, the spray has a special spray nozzle, and the drops have a dosing spout.
Both forms of Tizin include the same active substance - xylometazoline hydrochloride. It is included in the list of the most necessary medicinal products to eliminate swelling of the nasal mucosa. Preparations based on it quickly constrict blood vessels, facilitate nasal breathing, and are actively used in pediatrics.
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In addition to the main component, the medication includes the following components:
- sodium chloride. Acts as a solvent, because it is combined with many components of drugs;
- benzalkonium chloride. It has a bactericidal effect against various fungi, staphylococci, staphylococci, Pseudomonas aeruginosa, mold;
- disodium edetate. Helps remove the active component of the drug due to the ability to form ionic compounds with certain metals;
- sodium dihydrogen phosphate dihydrate. Used to normalize the secretory fluid of the mucous membranes to an optimal pH balance;
- disodium phosphate dihydrate. Includes all of the above effects, accelerates the action of the active component, and has a beneficial effect on the healing process;
- sorbitol. Performs a detoxification role;
- purified water. Acts as a solvent for all existing components.
The combination of useful elements of the medicinal product has a complex effect, quickly facilitates nasal breathing, and copes with eye ailments.
Indications for use
Tizin is well tolerated by young patients; for safety reasons, consult your pediatrician before starting use. The instructions for the medication recommend using Tizin to eliminate the following problems:
- acute rhinitis (runny nose that accompanies acute respiratory infections or acute respiratory viral infections, infectious diseases);
- hay fever (a chronic allergic reaction caused by individual intolerance to pollen);
- sinusitis (is an inflammation of the paranasal sinuses that occurs against the background of untreated rhinitis, due to complex infectious diseases previously suffered by the child, for example, measles, influenza with complications);
- conjunctivitis, which is accompanied by swelling;
- the drug is prescribed as an adjunct to general therapy for acute otitis; the disease often occurs in young children.
The variety of uses of the product is due to the fact that the drug solves nasal problems and copes with eye diseases in children. It is important to strictly follow the instructions and not exceed the indicated dosage.
Contraindications
In most cases, the drug is well tolerated; there are some contraindications, non-compliance with which has a sharply negative impact on the child’s health.
Tizin is prohibited from use in the following cases:
- for spray and drops with a dosage of the active substance - 0.1 dose is recommended for children after six years;
- for a 0.5% spray, use is allowed from the age of two;
- if you are hypersensitive to certain components of the drug, if negative consequences occur, stop taking it immediately and consult a doctor;
- It is not recommended to combine the medicine with MAO inhibitors or other medications that increase blood pressure;
- There are few reviews about the lactation period, but it’s not worth the risk. Women who are breastfeeding should abstain or consult their doctor before using Tizin;
- Additional consultation is necessary for those children who have problems with the liver, kidneys, or diabetes.
To obtain the desired result, treat your child under the close supervision of a doctor. Timely detection of side effects will protect the baby from complications and help quickly cope with the disease.
Possible side effects
Tizin is well tolerated for children, but there are some reviews from parents about the appearance of undesirable effects after using the medicinal product. It is important to know the side effects; if the baby’s condition worsens, consult a doctor:
- paresthesia. The condition is characterized by a sudden sensation of tingling, crawling, numbness at the site of use of the medication;
- burning sensation, often a side effect refers to the mucous membranes of the nose, less often – the eyes;
- dryness of the nasal mucous membranes (more often occurs against the background of uncontrolled, prolonged or frequent use of the drug);
- hypersecretion. The pathological process is first characterized by copious discharge from the nasal cavity, over time it becomes thick with impurities of pus, there are signs of intoxication of the body;
- medicinal rhinitis is a persistent runny nose that appears while taking a specific drug and appears even a week after stopping use of the spray;
- dry rhinitis. The condition is characterized by drying out of the nasal mucosa, the formation of crusts on it, and constant nasal congestion;
- increased eye fatigue, feeling of constant dryness.
The medication has a number of contraindications and side effects; for safety reasons, parents are not recommended to violate the established rules and specific dosage.
Instructions for use and dosage
In order for the effectiveness of the medicinal product to be high, it is necessary to adhere to certain instructions. When treating eye diseases, the instructions recommend using the drug 2-3 times a day; instill it directly into the baby’s conjunctival sac. The spray should be injected with a maximum of three doses into each nasal passage, it all depends on the age, weight and illness of the child.
For children under six years of age, it is not recommended to use the medication more than four times a day; the interval should be at least 4 hours. To avoid negative consequences, be sure to consult a specialist and strictly follow the dosage indicated by him.
Before using the spray, be sure to shake the bottle, press the sprayer several times until a normal “spray” forms, only then insert the end of the bottle into the child’s nasal cavity. Then press the required number of times, hold the device vertically, it is forbidden to use the spray with the bottle positioned down or to the side. For comfort, let the baby tilt his head slightly back.
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The approximate course of treatment is no more than seven days, the best option is treatment for 4 days. The approximate dosage for children is as follows:
- Tizin at a dosage of 0.05% is prescribed one dose into each nasal passage up to two times a day. This aspect applies to children under six years of age;
- Children from six to twelve years old are allowed Tizin at a dosage of 0.1%, one dose three times a day.
The drops are prescribed according to the same scheme, the eye treatment is carried out exclusively by the doctor, the exact dosage and duration of treatment are also indicated by the children's ophthalmologist or pediatrician.
Cost and storage conditions
The price of Tizin Xylo Bio for children in a dosage of 0.05% is approximately 180 rubles per package, a similar product with a dosage of 0.1% is 10 rubles more expensive. The price of Tizin drops varies within rubles per bottle, depending on the dosage of the active component. The cost is also affected by the city of purchase and the specific pharmacy chain.
The instructions recommend storing Tizin drops and spray at a temperature not exceeding 25 degrees Celsius; the shelf life of medicinal products does not exceed 36 months. It is recommended to store an open bottle for about three months; after this time, the medication cannot be used.
Analogs of a medicinal product
The pharmacological industry produces many medications with similar clinical effects to the drug. If for any reason Tizin is not suitable for your baby, replace it with another medicine. Analogues of the drug include:
Before using any medicine, consult your doctor and carefully read the instructions.
Tizin for children shows excellent results, quickly copes with rhinitis and eye diseases of various etiologies. The universal medicinal product is well tolerated by the child's body and rarely causes side effects. The main thing is to stick to the dosage and not use the product often.
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