How to take sumamed for adults

Posted on by admin

How to take Sumamed - dosage and pharmacological features of the drug

Sumamed is a broad-spectrum antibiotic that is prescribed to treat various infections. This is an original drug, during the development of which a lot of serious research was carried out, so there is no doubt about its effectiveness.

Table of contents:

The active ingredient is azithromycin - this is a representative group of macrolide antibiotics, which began to be used relatively recently. The drug has several advantages and is easy to use.

Pharmacological action and features

The answer to the question of how to take Sumamed depends on its properties and therapeutic effect. It usually comes in the form of tablets, capsules or powder (for suspension) for internal use - they dissolve well and are absorbed in the digestive tract. The drug substance is resistant to the effects of gastric juice, in addition, it is able to penetrate the membrane of living cells - this allows it to be used to combat various intracellular infections.

Azithromycin itself slows the growth of bacteria and makes them more vulnerable to attack by the immune system. When the drug accumulates in organs and tissues, it begins to have a bactericidal effect.

If used incorrectly and the dosage is not observed, bacteria can become resistant to the effects of antibiotics, but normally it can affect several groups of microorganisms:

  1. Streptococci and staphylococci. These bacteria can provoke streptococcal sore throat, kidney inflammation, scarlet fever and other diseases. Sumamed is one of the most effective drugs to date for these bacterial infections.
  2. Intracellular parasites such as chlamydia, mycoplasma and others. Sumamed is prescribed for sexually transmitted diseases; it is able to resist many sexually transmitted infections.
  3. Anaerobic microorganisms such as clostridia. These bacteria can cause dangerous diseases such as tetanus and botulism. The use of antibiotics saves the patient's life and prevents serious complications.

To determine the group of microorganisms, the doctor will prescribe a number of diagnostic procedures: these are urine and blood tests, as well as a throat smear (for sore throat) and some other types of tests. They help establish a diagnosis and choose the most effective antibiotic.

Indications for use and contraindications

Sumamed is prescribed for infectious and inflammatory processes of the respiratory tract and ENT organs: including pneumonia, bronchitis, laryngitis, tonsillitis, otitis media, tonsillitis, sinusitis and others.

In addition, Sumamed can be prescribed for Lyme disease, borreliosis, erythema and some other diseases. It is available in the form of tablets, suspension or capsules; in all cases, you must follow the instructions and calculate the dosage correctly.

In addition, Sumamed is prescribed for infectious skin diseases and inflammatory processes: including acne, erysipelas, dermatosis and many other skin problems.

Broad-spectrum antibiotics can only be prescribed by a doctor: uncontrolled use can lead to a decrease in their effectiveness and numerous side effects.

Sumamed, like any potent drug, has a number of absolute contraindications. It is not prescribed in the following cases:

  • During lactation. Contraindication is age up to 6 months; at a later date, a suspension may be prescribed. From three years of age, tablets with a dosage of 125 mg can be prescribed; from 12 years of age, the dosage of tablets increases to 450 mg.
  • During pregnancy, Sumamed is not prescribed unless there is a serious threat to the health of the mother. However, it is recommended as the main remedy for combating certain sexually transmitted infections.
  • Contraindication is impaired functioning of the kidneys and liver. The active substance is excreted from the body for quite a long time, and the main part of it is removed in the urine. Renal failure prevents this, so the drug is not prescribed.
  • The use of Sumamed is not recommended for diabetes mellitus, cardiac disorders: arrhythmia, heart failure, etc.

In addition, there are restrictions on use together with other drugs. It is not prescribed at all with digoxin and terfenadine; in all cases, only a doctor can prescribe the correct course of treatment.

Rules for taking Sumamed for adults

Sumamed - dosage for adults

How to take Sumamed? The dosage and method of administration depend on the patient’s age and some other parameters. In all cases, the medicine is taken once a day an hour before a meal or an hour after it.

Adults are prescribed tablets and capsules; the standard dosage for a patient over 12 years of age and weighing more than 45 kg is 500 mg.

The course of treatment depends on the disease:

  • For infectious diseases of the respiratory tract and ENT organs, 500 mg of the drug per day is prescribed, once a day. The course of treatment takes 3 days. After this, the doctor will evaluate changes in the patient’s condition and decide on the further use of antibiotics.
  • For Lyme disease, a 5-day course of treatment is prescribed: on the first day you need to take 1 g of the drug, on the remaining days the dose is halved. The total dose taken by the patient should not exceed 3 g.
  • For pharyngitis and tonsillitis, take 500 mg of the drug once a day.
  • When treating skin diseases and acne, the course of treatment will be longer. In the first three days, the patient should take 500 mg of the drug once a day, then for 9 weeks, take 500 mg once a week. The drug is taken strictly every 7 days.
  • For urethritis and other infectious and inflammatory processes in the urinary tract, an antibiotic is prescribed once in an amount of 1 gram. This is only part of the course of treatment; all recommendations of specialists must be followed.

This information is advisory in nature. Depending on the course of the disease and the characteristics of the patient’s body, the dosage changes and is prescribed by the attending physician. To prevent serious side effects, you should not purchase and use the drug yourself, even on the basis of medical recommendations in the instructions.

Rules for taking Sumamed for children

Sumamed - dosage for children

For children, the method of administration and possible dosage depend on age and body weight: for children weighing less than 45 kg under the age of 12 years, the dosage is 10 mg per kilogram of weight. For infectious diseases of the respiratory tract and ENT organs, the course of treatment is usually 3 days, the drug is administered in a precisely calculated dose once a day.

For Lyme disease, the course of treatment takes 5 days: on the first day the medicine is taken at a rate of 20 mg/kg, from days 2 to 5 it is halved.

Thus, the total amount of antibiotic taken should not exceed 60 mg per kg of the child’s weight.

Children are usually prescribed tablets and capsules, the dosage of which is 125 g. Depending on the child’s weight, the doctor will prescribe 2 or 3 tablets.

For small children under 3 years of age, the dosage is calculated in a similar way:

  • When treating infections, a 3-day course will be prescribed with a dose of 10 mg of the drug per kilogram of weight; the treatment for tonsillitis and other diseases caused by streptococci will be similar.
  • For Lyme disease, a 5-day course will be prescribed according to the above scheme, the total dosage during the entire course of treatment should not exceed 60 mg/kg.
  • Small children are prescribed not tablets, but a suspension; it must be thoroughly mixed and brought to a homogeneous consistency.

Video on how to prepare the “Sumamed” suspension.

An overdose when treating children is completely unacceptable, so you must not violate the treatment period and the schedule prescribed by the doctor. There are often situations when parents try to speed up recovery and increase the dose for this. This will not only not help the child, but can lead to a serious deterioration in well-being.

Parents are advised to keep a diary in which all medications taken and their effects should be recorded. If any signs of allergies or individual intolerance appear, the doctor will select other medications, and keeping a diary will greatly facilitate his work. In addition, it will allow you to notice positive changes in your well-being.

Possible side effects

When taking Sumamed, some negative side effects are possible due to the pharmacological action of the drug.

They can manifest themselves depending on the characteristics of the body, the most common are the following phenomena:
  • Digestive system. Abdominal pain, nausea and vomiting, symptoms of gastritis, and bloating may occur. With long-term use or uncontrolled use, drug-induced hepatitis and severe liver dysfunction are possible.
  • Nervous system. Possible sleep disturbances, increased fatigue, dizziness, as well as disturbances of smell and touch. When treating otitis media in children, a side effect of Sumamed may be headache.
  • In case of individual intolerance to the components of the drug, severe allergic reactions are possible: Quincke's edema, increased sensitivity to light, skin rashes, itching, rash.
  • Cardiovascular system: heart palpitations may occur. If you already have heart problems, an exacerbation of chronic diseases is possible.

Side effects do not occur often: they may be associated with individual sensitivity to the components of the drug. If any allergic reactions to antibiotics have previously been observed, this should be reported to a specialist.

A solid list of side effects partly confirms the effectiveness of the drug: the potent substance affects all organs and systems, which is why it is so important to strictly follow the instructions and prescribe an antibiotic only when it is really necessary.

With prolonged use, serious disturbances in the functioning of the digestive system are possible.

The antibiotic destroys the beneficial intestinal microflora, which can cause dysbiosis and require special treatment. An overdose is manifested by symptoms of poisoning: nausea, vomiting, bowel movements, and temporary hearing loss is possible. No special treatment is required; symptom relief is sufficient.

Sumamed is an effective antibiotic that allows you to fight various infections and get quick results; the new drug has proven itself well and is widely used.

Readers liked:

Share with your friends! Be healthy!

Comments (5)

Elena

10/16/2015 at 11:31 pm | #

I often deal with sumamed and its analogue azithromycin, since sinusitis is my eternal problem, and this antibiotic has helped me out more than once. Its effectiveness is partly due to the fact (this is mentioned in passing in the article) that it accumulates not just in tissues, but specifically in areas of inflammation (it is transported there along with phagocytes) and acts precisely in the place where bacteria accumulate. In addition, its effect is prolonged, that is, after a 3-day course it acts in the body for several more days. But during pregnancy and lactation it is strictly contraindicated - as it has a negative effect on the child’s bone tissue (the ENT doctor at the hospital warned).

Irina

08/23/2017 at 05:16 | #

For some reason, my husband was prescribed it for six days, plus he was additionally told to go on Smartprost, supposedly because the drugs penetrate very poorly into the inflamed prostate. But it helped, apparently, such a scheme also has a right to exist.

Marat

10/30/2017 at 15:05 | #

I took 500 mg for prostatitis for 3 days, then I just finished treatment with suppositories and smartprost. so this dose is quite enough for an adult man.

Rustam

01/21/2018 at 09:01 | #

Maybe with this approach it will help, but not everyone has the opportunity to complete treatment with smartprost

02/19/2018 at 11:50 | #

in fact, if you look at it, it turns out that smartprost is even more profitable than medications. I bought it once and for life.

leave a comment

Medicines

We recommend reading:

Our pages

Discussions

  • Svetlana – I use laundry soap for cosmetology. – 03/11/2018
  • Galetova S.D. – We do not use it when there is congestion. – 03/10/2018
  • Anita - I treat my throat with gargles. – 03/10/2018
  • Vlada – I have been weak all my life. – 03/10/2018
  • Eva Tsarskaya - My son (7 years old) was sick. – 03/09/2018
  • Lilya - Some are treated with what, some with tea. – 03/09/2018

The medical information published on this page is strictly not recommended for self-medication. If you feel negative changes in your health, immediately contact an ENT specialist. All articles published on our resource are for informational purposes only. If you use this material or a fragment of it on your website, an active link to the source is required.

Source: http://tvojlor.com/lekarstva/kak-prinimat-sumamed-dozirovka-i-farmakologicheskie-osobennosti-preparata.html

Sumamed - instructions for use

One of the most popular modern broad-spectrum antibiotics is Sumamed. The main active ingredient of the drug is azithromycin, which belongs to a new subgroup of macrolides - azalides. Thanks to some chemical changes in the formula of classical macrolides, Sumamed acquired special properties. The drug is highly resistant to the action of gastric juice, has increased penetrating ability, which allows azithromycin molecules to easily enter cells. The concentration of Sumamed in areas of inflammation is tens of times higher than its concentration in the blood. In addition, azithromycin easily penetrates cell membranes, which determines its pronounced effect in the treatment of diseases caused by intracellular infections.

It should be noted that Sumamed is an original drug, so we can say with confidence that all aspects of its action have been carefully studied and tested in many clinical trials.

Azithromycin itself has an inhibitory effect on the growth and development of bacteria, but when it accumulates in high concentrations in inflamed tissues, it also causes a bactericidal effect. It is known that pathogens can be immune to the effects of antibiotics both initially and acquire this resistance during their life activity. Resistance to Sumamed of such microorganisms as Streptococcus pneumoniae, Enterococcus faecalis, Bacteroides fragilis, methicillin-resistant strains of Staphylococcus aureus and Staphylococcus epidermidis is possible. To determine the direct sensitivity of microorganisms to a drug, it is necessary to perform bacteriological culture to determine resistance to certain drugs.

However, in general cases Sumamed is active against the following microorganisms:

  • the vast majority of gram-positive aerobic bacteria (the main types of staphylococcus and streptococcus)
  • the vast majority of gram-negative aerobic pathogens (Haemophilus influenzae, Legionella, Moraxella, Neisseria)
  • many anaerobic microorganisms (clostridia, fusobacteria, bacteria of the genus Prevotella and porphyriomonas);
  • intracellular pathogenic organisms (chlamydia, mycoplasma, borrelia).

Sumamed is available in a variety of dosage forms: tablets and capsules (125, 250 and 500 mg each), powder for suspension, as well as forms for injection.

Indications for use

Sumamed is prescribed for infections caused by organisms sensitive to the components of the drug:

  • infectious and inflammatory diseases of the upper and lower respiratory tract (acute and chronic bronchitis in the acute stage, pneumonia);
  • infectious and inflammatory diseases of the ENT organs (tonsillitis, pharyngitis, tonsillitis, sinusitis, otitis media);
  • infectious and inflammatory diseases of the skin and soft tissues (moderate acne, erysipelas, secondary infected dermatoses);
  • Lyme disease (infectious borreliosis) in the stage of erythema migrans (initial stage);
  • infectious and inflammatory diseases of the genitourinary tract caused by the pathogen Chlamydia trachomatis (urethritis, cervicitis).

Contraindications

Absolute contraindications to the use of the drug Sumamed are:

  • hypersensitivity to azithromycin (as well as other macrolides) and other components of the drug;
  • severe liver dysfunction;
  • severe renal dysfunction (creatinine clearance less than 40 ml/min);
  • children under 12 years of age for children weighing less than 45 kg (for tablets 500 mg);
  • children under 3 years of age (for taking tablets at a dosage of 125 mg);
  • children up to 6 months of age (for taking powder for preparing a suspension);
  • lactation period (breastfeeding period);
  • combined use with ergotamine and dihydroergotamine.
  • The drug should be taken with caution in the following conditions:
  • moderately severe liver dysfunction;
  • moderately severe renal dysfunction (creatinine clearance more than 40 ml/min);
  • myasthenia gravis;
  • disorders of the cardiovascular system: arrhythmia and ECG changes in the form of prolongation of the QT interval (for patients taking antiarrhythmic drugs of classes IA, III, as well as the drug cisapride); low levels of potassium and magnesium in the blood, marked slowing of heart rate and severe heart failure;
  • diabetes;
  • co-administration of the drug with terfenadine, warfarin and digoxin.

How to use

Sumamed tablets and capsules are recommended to be taken 1 time per day in isolation from meals: before meals (at least 1 hour before) or after meals (at least 2 hours after).

For children, the dose of the drug is determined based on each kilogram of the child’s body weight.

The suspension is prepared immediately before the first use and stored for no more than 5 days. To completely dissolve the powder, add liquid

It is administered in two doses and the entire contents of the bottle are thoroughly mixed until a homogeneous mass is formed. The required dose is measured using a syringe or measuring spoon. Before each new dose, the suspension must be shaken thoroughly.

Also, for adult patients and children over 12 years of age weighing more than 45 kg, Sumamed is prescribed for the treatment of moderate acne at a dose of 500 mg once a day for 3 days. Afterwards - 500 mg once a week for 9 weeks. The total dose per course of treatment is 6 g. The first weekly dose is required on the 8th day from the start of treatment of the disease, the next 8 weekly doses must be taken every 7 days.

For the treatment of infectious and inflammatory diseases of the genitourinary tract caused by Chlamydia trachomatis (urethritis, cervicitis), a single dose of 1 gram of the drug is prescribed.

Side effects

The following side effects occur when taking the drug:

  • From the digestive system: decreased appetite, nausea, vomiting, stool upset, epigastric pain, bloating, gastritis, reversible increase in the activity of liver enzymes, cholestatic jaundice, hepatitis, liver failure;
  • Allergic reactions: itching, skin rashes, Quincke's edema, urticaria, photosensitivity;
  • From laboratory parameters: in some cases, a reversible decrease in the level of lymphocytes, an increase in the number of eosinophils;
  • From the nervous system: dizziness, headache, increased fatigue, impaired sensitivity of the organs of smell, touch and tactile sensitivity, increased anxiety, insomnia or increased drowsiness; children may experience headaches (during treatment of otitis media);
  • From the reproductive system: vaginal candidiasis;
  • From the cardiovascular system: rapid heartbeat;
  • From the urinary system: nephritis;
  • There is also general weakness, loss of appetite, and joint pain.

An overdose of Sumamed causes nausea, vomiting, stool upset, and temporary hearing loss may develop. No specific treatment is required; symptomatic therapy is necessary.

During pregnancy and lactation

The use of Sumamed during pregnancy and lactation is recommended only in special cases when the benefit obtained will be higher than the possible risk. However, the World Health Organization recommends this particular drug as the main treatment for chlamydial infection in pregnant women.

Since azithromycin passes into breast milk, if it is necessary to prescribe Sumamed during lactation, breastfeeding should be suspended.

Drug interactions with other drugs

Antacids (in particular those containing aluminum and magnesium), as well as alcohol and food intake, significantly reduce the absorption of Sumamed, so the drug must be taken in isolation from food and intake of these substances (take Sumamed at least 1 hour before or 2 hours after).

It is also necessary to be careful when co-prescribing the drug with anticoagulants and antiplatelet agents. When taking warfarin, prothrombin time should be monitored. Taking heparin together with Sumamed is contraindicated.

Source: http://vetinpharm.com/antibiotiki/sumamed-instruktsiya-po-primeneniyu.html

Sumamed

Sumamed (azithromycin) belongs to the semisynthetic antibiotics of the azalide subclass and has a bacteriostatic effect.

Instructions for use

Azithromycin has a detrimental effect on:

  • gram-positive cocci: streptococci from groups CF and G, St. Viridans, St. Pyogenes, Staphylococcus aureus;
  • anaerobic microorganisms: Clostridium perfringens, Bacteroides bivius;
  • gram-negative bacteria: Campylobacter jejuni, Bordetella pertussis, Legionella pneumophila, Haemophilus influenzae, B. parapertussis, H. ducrei, Gardnerella vaginalis;
  • other pathogenic microorganisms: Chlamydia trachomatis, Treponema pallidum, Mycoplasma pneumoniae, Borrelia burgdoferi.

Sumamed does not have a detrimental effect on gram-positive microorganisms that are resistant to erythromycin.

Pharmacokinetics

Sumamed is resistant to the acidic environment of the gastrointestinal tract, which is why when it enters the intestines it begins to be actively absorbed; when using 500 mg. After 3 hours of the drug, the maximum dose of azithromycin will accumulate in the blood, while the ability of the drug to be absorbed is more than 35%.

Distribution of Sumamed throughout the body

Sumamed has a good ability to penetrate the respiratory tract, genitourinary organs and eukaryotic cells of the body. This increased therapeutic effect is explained by the fact that Sumamed binds poorly to blood proteins and accumulates in tissues with low pH levels near lysosomes.

The ability of sumamed to accumulate precisely in lysosomes, which are responsible for the digestion of foreign bacteria that penetrate the human body, allows the drug to have increased activity against intracellular microorganisms. Azithromycin acts selectively and is distributed predominantly in pathological tissues, with signs of an inflammatory process.

With the help of phagocytes (protective cells of the immune system), azithromycin is delivered to organs and tissues affected by the infectious process. This does not have a negative impact on the functional abilities of phagocytes. Due to the fact that the effect of the antibiotic can persist for a week after the last dose, azithromycin is taken in short courses.

Sumamed is eliminated from blood plasma gradually, in several stages. This allows you to use the product only once a day.

Indications for use

  • infectious diseases of the ENT organs: sinusitis, pharyngitis, otitis media, tonsillitis, laryngitis, pneumonia, sinusitis, bronchitis;
  • chlamydial infections of the genitourinary tract: cervicitis, urethritis;
  • ulcerative processes in the stomach and duodenum caused by Helicobacter pylori;
  • pustular skin diseases;
  • skin infections;
  • dermatoses complicated by an infectious process;
  • Lyme disease.

Method of use of the drug

Sumamed, like any other antibacterial agent, should be taken only in consultation with a doctor. Take azithromycin in the prescribed dosage, once a day - 1 hour before a meal or 2 hours after a meal.

For adult patients, Sumamed is prescribed in a dosage of mg. 1 time per day - depending on the location of the pathogen. For children, the antibiotic is prescribed at 10 mg/kg body weight for 3 days. If a child is sick with chronic migratory erythema (dermatosis caused by Borrelia), then on the first day of illness it is recommended to take azithromycin 20 mg/kg, and then for another 4 days 10 mg/kg.

Side effects

  • nausea, vomiting;
  • diarrhea;
  • increased gas formation;
  • allergic reactions in the form of skin rashes.

Contraindications

  • tendency to allergic diseases;
  • pregnancy, lactation period;
  • increased sensitivity of the body to macrolides;
  • disruption of the liver and kidneys.

Interaction with other drugs

Sumamed tends to enhance the effects of: tetracyclines, ergot alkaloids, chloramphenicol. Some medications reduce the therapeutic effect of Sumamed. Among them: lincosamides, antacid drugs.

Sumamed should not be taken with food, as this can slow down the absorption of the antibiotic. It is incompatible with heparin and can increase the toxic effect of certain drugs: cycloserine, methylprednisolone, felodipine, etc. Overdose causes nausea, vomiting, diarrhea, and possible dullness or loss of hearing.

Release form and storage rules

Sumamed is available in the form of tablets, capsules and powder for suspension. Children are usually prescribed the drug in powder.

The product must be stored at a temperature of °C, away from direct sunlight and children.

Video

How to distinguish the drug "Sumamed" from a fake?

Frequently asked questions, reviews

Can pregnant women use sumamed?

One of the relative contraindications to taking azithromycin is pregnancy. The use of the drug is justified only when the benefits of treatment outweigh the potential risk to the fetus. It is extremely undesirable to drink sumamed in the first trimester of pregnancy, when germ cells are actively multiplying and the most important organs and systems of the unborn child are being formed.

Is Sumamed compatible with alcohol?

Any medicine should not be taken while drinking alcohol, as they reduce the therapeutic effect of taking the medicine and increase the load on the kidneys and liver. It is worth considering that sumamed is completely eliminated from the body within 5-7 days after the last dose. Thus, drinking alcohol is not recommended during this period.

Source: http://www.doctorfm.ru/drugs/sumamed

Features of the use of the antibiotic Sumamed for adults

The drug Sumamed is a broad-spectrum antibiotic. Its active principle is azithromycin, which was synthesized in 1980 by Croatian scientists from the Pliva company.

It is the first drug of the azalide subclass. Azithromycin differs slightly in chemical structure from the classical macrolide antibiotics, to which Erythromycin belongs.

It is based on a 15-membered lactam ring, due to which it exhibits greater activity against pathogenic microflora. While other macrolides are based on a 14 or 16-membered lactam ring.

Another difference between azithromycin and other antibiotics in this group is the long period of elimination from the body. Therefore, it can be prescribed once a day in short courses. So, if the duration of treatment with Erythromycin can be 2 weeks, and you need to drink it up to 4 times a day, then the course of therapy with Sumamed lasts only 3 to 5 days.

Spectrum of antimicrobial activity of Sumamed

Sumamed, a bacteriostatic antibiotic, is active against many microorganisms, including:

  • streptococci, including methicillin-sensitive strains;
  • Staphylococcus aureus;
  • pneumococci;
  • Moraxella;
  • gonococcus;
  • Pfeiffer wand;
  • mycoplasma;
  • whooping cough stick;
  • ureaplasma;
  • Pseudomonas aeruginosa;
  • legionella;
  • Borrelia.

Azithromycin is inactive against gram-positive microorganisms that are immune to erythromycin, methicillin-resistant colonies of streptococci, fecal enterococcus and bacteroides fragilis.

Once in the body, the active substance Sumamed interacts with the 50S ribosomal subunit, blocks the translocase enzyme at the translation stage, as a result, protein formation by the microbial cell is disrupted, and the growth and division of microorganisms is suspended.

But what effect azithromycin has depends on the dose; in high concentrations it causes the death of the pathogenic agent.

Pharmacokinetics

After oral administration, azithromycin is quickly adsorbed from the digestive tract, after 2.1-3.2 hours its peak concentration is observed in the bloodstream.

The active substance is able to pass through the cell membrane, so the antibiotic inhibits the growth of intracellular microorganisms, which include chlamydia.

Once inside, the active principle quickly migrates through the bloodstream directly to the site of infection, reaching a concentration here that is 25–30% higher than in healthy organs. The active substance is lipophilic, due to which it is well absorbed by tissues, in which its level is 50 times higher than in the vascular bed.

Azithromycin is slowly eliminated from the body; after the last dose, it is still able to provide a therapeutic effect for a week. That is why Sumamed is taken in short courses.

Intended use and contraindications

The instructions for use of the drug Sumamed state that it is effective in the following cases:

  • infections of the upper and lower respiratory tract, ENT, including inflammation of the throat, paranasal sinuses, lungs, ear, bronchi;
  • diseases of the skin and soft tissues, including erysipelas, pyoderma, acne;
  • chlamydia, non-gonorrheal and gonorrheal inflammation of the urethra and uterus;
  • peptic ulcer of the stomach and duodenum (in parallel with other medications);
  • the first signs of tick-borne borreliosis.

The instructions for the medication Sumamed state that it is contraindicated if the patient has:

  • individual intolerance to the composition of the drug, as well as other macrolide antibiotics;
  • serious liver pathologies;
  • lactase deficiency;
  • parallel treatment with ergotamine and dihydroergotamine.

The drug should be used with caution if the patient suffers from such pathologies as:

  • myasthenia gravis;
  • severe renal dysfunction;
  • minor malfunctions in the functioning of the liver;
  • abnormalities of the cardiovascular system, such as decreases and interruptions in heartbeat, heart failure, increases in the QT interval;
  • diabetes;
  • decreased levels of sodium and magnesium in the blood.

In addition, azithromycin can interact with many medications, so it is necessary to inform your doctor about all medications you are taking.

Prescriptions of Sumamed in pediatrics, during pregnancy and lactation

Sumamed cannot be used to treat patients under 6 months of age; the drug is not prescribed for injection to persons under 16 years of age.

Azithromycin is approved for use for health reasons in pregnant and lactating women, when the benefit to the mother outweighs the danger to the baby.

Since the active substance passes into breast milk, it will be better if the child is transferred to an adaptation formula for the period of therapy.

Adverse reactions and cases of overdose

Sumamed is usually well tolerated by patients, but still, during treatment, it may also experience undesirable effects.

Most often, when taking azithromycin, digestive disorders develop, such as:

These side effects are observed in more than 10% of patients, they are easily eliminated, and do not require stopping the medication.

In 1–10% of patients during therapy, the following is noted:

  • loss of appetite, up to complete refusal to eat and the development of anorexia;
  • headache, the most common nervous system disorder;
  • vertigo;
  • hearing problems such as tinnitus and hearing loss, especially when treated with large doses of the drug, but these phenomena completely disappear after completion of the course of therapy;
  • allergic reactions, including skin itching, Quincke's edema, anaphylaxis; to reduce the likelihood of their occurrence, it is recommended to take antiallergic drugs in parallel with Sumamed, for example, Cetrin, Erius;
  • visual disturbances that completely disappear after stopping the medication.

0.1–1% of citizens receiving Sumamed reported the following adverse reactions:

  • increased growth of fungi of the genus Candida;
  • proliferation of pathogenic microflora and development of inflammation of the oral cavity, lungs, nose, pseudomembranous colitis;
  • pain in muscles and joints;
  • dysuria;
  • menstrual disorder, ovarian dysfunction;
  • temperature increase;
  • chronic fatigue;
  • hepatitis and increased levels of bilirubin in the blood, which develop with long-term use of azithromycin;
  • swelling of the face and limbs;
  • chest pain;
  • dyspnea;
  • nose bleed.

In addition, during treatment, severe renal failure, hallucinations, and loss of consciousness may develop.

In isolated cases, a prolongation of the QT interval is possible, which is clinically manifested by cardiac arrhythmias and ventricular tachycardia. Arrhythmia can cause the death of a patient, especially if he is taking antiarrhythmic drugs.

In case of an overdose of the drug, temporary hearing loss, nausea, vomiting, and stomach upset are observed. There is no specific antidote. The victim is advised to lavage the stomach, take sorbents and saline solutions, which help eliminate dehydration that develops due to vomiting and diarrhea.

Release form and treatment regimen for adults

The drug Sumamed has several release forms for both enteral and parenteral use.

The injection form is a lyophilisate for the preparation of a solution for infusion.

For children, the medication is developed in the form of suspensions. Sumamed tablets are presented in 2 dosages of 125 mg and 500 mg. There is a capsule form of the medication; each capsule contains 250 mg of active ingredient.

For adults, the drug is prescribed in the form of infusion solutions, capsules or tablets. The dosage of Sumamed is selected individually depending on the type of infection.

Capsules and tablets are swallowed whole, either an hour before meals or 2 hours after meals. Sumamed for adults weighing more than 45 kg for infections of the ENT organs and respiratory system is prescribed in a dosage of 500 mg once a day, the course of therapy is 3 days.

  • For tick-borne borreliosis, the duration of taking the medication is 5 days. Azithromycin is also taken once a day, on the first day at a dosage of 1 g, on subsequent days at a dose of 500 mg.
  • For chlamydia, as well as uncomplicated inflammation of the uterus and urinary canal, the medication is prescribed once in a dosage of 1 g.
  • For acne, the drug is taken in a dosage of 500 mg once a day for 3 days, after which the drug in a dosage of 500 mg is taken once a week for 9 weeks. In total, you need to drink 6 g of Sumamed per course. The first weekly dose is taken on the 8th day of therapy, the remaining 8 doses every week.

In severe cases, Sumamed is prescribed intravenously; infusions can only be administered in a hospital setting.

Pharmacological compatibility

When prescribing Sumamed tablets, you need to take into account that they may be incompatible with some medications.

  • Thus, when azithromycin and cardiac glycosides are taken together, the concentration of the latter increases in the vascular bed.
  • With the parallel administration of Sumamed and indirect anticoagulants, an increase in blood clotting time was observed.
  • When taking azithromycin and rifabutin simultaneously, agranulocytosis occurred in some patients.
  • Terfenadine and combinations with Sumamed increases the likelihood of prolongation of the QT interval and interruptions in myocardial contraction.

Rules for storage and sale from a pharmacy

Like any other antibiotics, Sumamed is sold from pharmacies strictly according to a doctor’s prescription. Store the medication out of the reach of children at an ambient temperature of a maximum of 25 degrees.

Patients have many questions about which antibiotic (azithromycin or Sumamed) is better. Let's try to understand this issue thoroughly.

Sumamed is an antibiotic with a wide range of uses. It is equally suitable for people. From the age of twelve, an adult dose of 0.5-1 g per day is required, it is determined by the doctor based on the diagnosis.

First, it should be noted that both Sumamed and Amoxiclav belong to the group of antibiotics, with. Long-term use of the drugs has shown that the incidence of side effects in children does not differ significantly from adults.

. is actively used by employees of medical institutions in most countries both for the treatment of adult patients and . Pharmacy chains offer customers to purchase the antibiotic Sumamed for children in capsules, in solid form.

All forms of Sumamed contain only the above-mentioned antibiotic, although in different quantities. . For adult patients, Sumamed is usually prescribed in an amount of 500 mg; children - 10 milligrams per kilogram of weight.

Similar articles

Fusiderm B - instructions for use

Using Tobrex for children - are there any contraindications?

Areas of application and properties of alcohol solution of chloramphenicol

Leave a comment Cancel reply

Similar articles

Patients have many questions about which antibiotic (azithromycin or Sumamed) is better. Let's try to understand this issue thoroughly.

Sumamed is an antibiotic with a wide range of uses. It is equally suitable for people. From the age of twelve, an adult dose of 0.5-1 g per day is required, it is determined by the doctor based on the diagnosis.

Source: http://med-antibiotiki.ru/instrukcii/osobennosti-primeneniya-antibiotika-sumamed-dlya-vzroslyx/

Sumamed

Instructions for use:

Prices in online pharmacies:

Sumamed is a broad-spectrum antibacterial drug. It is an antibiotic of the macrolide group (azalide).

Release form and composition

Sumamed is available in the following dosage forms:

  • film-coated tablets, 125 mg: biconvex, round, blue, engraved “PLIVA” on one side and “125” on the other; a white or almost white core is visible on the fracture (6 pieces in blisters, 1 blister in a cardboard pack);
  • film-coated tablets, 500 mg: biconvex, oval, blue, engraved “PLIVA” on one side and “500” on the other; a white or almost white core is visible on the fracture (3 pieces in blisters, 1 blister in a cardboard pack);
  • dispersible tablets 125 mg: flat, round, white or almost white, with “TEVA 125” engraved on one side, with beveled edges (6 pieces in blisters, 1 blister in a cardboard box);
  • dispersible tablets 250 mg: flat, round, white or almost white, with “TEVA 250” engraved on one side and a score on the other, with beveled edges (6 pieces in blisters, 1 blister in a cardboard pack);
  • dispersible tablets 500 mg: flat, round, white or almost white, with “TEVA 500” engraved on one side and a score on the other, with beveled edges (3 pieces in blisters, 1 or 2 blisters in a cardboard pack);
  • dispersible tablets 1000 mg: flat, round, white or almost white, with “TEVA 1000” engraved on one side and two perpendicular marks on the other, with beveled edges (1 piece in blisters, 1 or 3 blisters in a cardboard pack) ;
  • hard gelatin capsules 250 mg: size No. 1, with a blue cap and blue body; contents – a compacted mass that disintegrates when pressed, or a white to light yellow powder (6 pieces in blisters, 1 blister in a cardboard box);
  • powder for the preparation of suspension for oral administration 100 mg/5 ml: white or yellowish-white, with a characteristic strawberry odor; ready-made suspension – homogeneous, yellowish-white, with the smell of strawberries (20.925 g in 50 ml polyethylene bottles, 1 bottle in a cardboard box complete with a dosing syringe and/or measuring spoon);
  • lyophilisate for preparing a solution for infusion: white or almost white powder (in clear glass bottles, 5 bottles in a cardboard box).

Composition of 1 film-coated tablet:

  • active ingredient: azithromycin (in the form of azithromycin dihydrate) – 125 mg or 500 mg;
  • auxiliary components: hypromellose, microcrystalline cellulose, magnesium stearate, corn starch, anhydrous calcium hydrogen phosphate, sodium lauryl sulfate, pregelatinized starch;
  • film shell: titanium dioxide, talc, hypromellose, polysorbate 80, indigo carmine dye.

Composition of 1 dispersible tablet:

  • active ingredient: azithromycin (in the form of azithromycin dihydrate) – 125, 250, 500 or 1000 mg;
  • auxiliary components: sodium lauryl sulfate, microcrystalline cellulose, povidone K30, sodium saccharinate dihydrate, colloidal silicon dioxide, crospovidone type A, magnesium stearate, aspartame, banana flavor (150 mg tablets) or orange (250 mg, 500 mg and 1000 mg tablets).

Composition of 1 capsule:

  • active ingredient: azithromycin (in the form of azithromycin dihydrate) – 250 mg;
  • auxiliary components: sodium lauryl sulfate, microcrystalline cellulose, magnesium stearate;
  • capsule shell composition: titanium dioxide, gelatin, indigo carmine.

Composition of 1 g of powder for preparing a suspension:

  • active ingredient: azithromycin (in the form of azithromycin dihydrate) – 23.895 mg;
  • auxiliary components: hyprolose, sucrose, titanium dioxide, sodium phosphate, xanthan gum, colloidal silicon dioxide, strawberry flavor.

Composition for 1 bottle with lyophilisate:

  • active ingredient: azithromycin (in the form of azithromycin dihydrate) – 500 mg;
  • auxiliary components: sodium hydroxide, citric acid monohydrate.

Indications for use

Sumamed is used for the treatment of infectious and inflammatory diseases caused by microorganisms sensitive to azithromycin:

  • infections of the ENT organs and upper respiratory tract (otitis media, sinusitis, tonsillitis, pharyngitis);
  • infections of the lower respiratory tract (pneumonia, exacerbation of chronic bronchitis, acute bronchitis, including infections caused by atypical microorganisms);
  • tick-borne borreliosis in the initial stage (Lyme disease);
  • infections of soft tissues and skin, for example, impetigo, erysipelas, acne vulgaris of moderate severity, secondary infected dermatoses (for Sumamed in tablet form);
  • genitourinary tract infections (cervicitis, urethritis), the causative agent of which is Chlamydia trachomatis (for Sumamed in the form of tablets and capsules).

Sumamed in the form of a lyophilisate for preparing a solution for infusion is used for community-acquired pneumonia and infectious and inflammatory diseases of the pelvic organs (salpingitis, endometritis) caused by Neisseria gonorrhoeae or Chlamydia trachomatis and Mycoplasma hominis.

Contraindications

  • severe renal dysfunction (creatinine clearance less than 40 ml/min);
  • severe liver dysfunction;
  • fructose intolerance, isomaltase/sucrase deficiency (for Sumamed in the form of a powder for the preparation of a suspension);
  • children up to 6 months (for Sumamed in the form of powder for preparing a suspension);
  • children under 3 years of age (for Sumamed in the form of tablets with a dosage of 125 mg);
  • children under 12 years of age and body weight less than 45 kg (for Sumamed in the form of tablets with a dosage of 500 mg and capsules);
  • children and adolescents up to 18 years of age (for Sumamed in the form of lyophilisate);
  • combined use with dihydroergotamine and ergotamine;
  • hypersensitivity to azithromycin or auxiliary components of the drug, as well as erythromycin, ketolides or other macrolides.

Relative (Sumamed is used with caution):

  • mild to moderate renal dysfunction (creatinine clearance more than 40 ml/min);
  • mild to moderate liver dysfunction;
  • the presence of proarrhythmogenic factors, especially in elderly patients (arrhythmia, clinically significant bradycardia, severe heart failure, hypomagnesemia or hypokalemia, acquired or congenital prolongation of the QT interval, concomitant use of class IA and III antiarrhythmic drugs, antidepressants, fluoroquinolones, antipsychotics, terfenadine and cisapride );
  • diabetes mellitus (for Sumamed in the form of powder for preparing a suspension);
  • simultaneous use of warfarin, digoxin or cyclosporine.

Directions for use and dosage

Film-coated tablets, dispersible tablets and capsules

Sumamed is taken orally 1 hour before meals or 2 hours after meals.

Recommended doses and duration of treatment for adults and children over 12 years of age weighing 45 kg or more:

  • infections of the ENT organs, respiratory tract, soft tissues and skin: 500 mg once a day, course of treatment – ​​3 days; for acne vulgaris of moderate severity after a standard 3-day course, treatment is continued for another 9 weeks (500 mg once a week);
  • initial stage of borreliosis: 1000 mg on the first day, 500 mg in subsequent days, course of treatment – ​​5 days;
  • uncomplicated cervicitis/urethritis: 1000 mg once.

Recommended doses and duration of treatment for children aged 3–12 years weighing less than 45 kg:

  • infections of the ENT organs, respiratory tract, soft tissues and skin: 10 mg/kg body weight once a day, course of treatment – ​​3 days;
  • tonsillitis/pharyngitis caused by Streptococcus pyogenes: 20 mg/kg once a day, course of treatment – ​​3 days (maximum dose is 500 mg per day);
  • initial stage of borreliosis: on the first day - 20 mg/kg once a day, on subsequent days - 10 mg/kg once a day, course of treatment - 5 days.

Oral suspension

Sumamed in the form of an oral suspension is prescribed to children aged 6 months to 3 years. The drug is taken once a day 1 hour before meals or 2 hours after meals. The suspension should be taken with a small amount of water.

To prepare the suspension, add 12 ml of water to the contents of the bottle with powder and shake thoroughly until a homogeneous consistency is obtained. The resulting volume will be about 25 ml, which is 5 ml more than the nominal volume. This discrepancy is provided in order to compensate for the inevitable loss of suspension when dosing Sumamed. The prepared suspension can be stored for no more than 5 days at a temperature not exceeding 25 °C.

The prepared suspension must be shaken thoroughly before each dose. The prescribed dose is measured using the supplied dosing syringe or measuring spoon, which should be rinsed and dried after each use.

The dosage of the suspension is similar to the recommended doses for the use of tablets in children 3–12 years old (1 ml of suspension contains 20 mg of azithromycin).

Lyophilisate for the preparation of solution for infusion

Sumamed is administered intravenously by drip over 1 hour (at a solution concentration of 2 mg/ml) or 3 hours (at a solution concentration of 1 mg/ml). Intramuscular or intravenous jet administration is prohibited.

The solution for infusion is prepared in 2 stages:

  1. Preparation of the reconstituted solution. Add 4.8 ml of water for injection to the bottle with lyophilisate and shake thoroughly until the powder is completely dissolved. 1 ml of the resulting solution contains 100 mg of azithromycin. The reconstituted solution is inspected for the presence of undissolved particles. If they are detected, the solution cannot be used.
  2. Dilution of the reconstituted solution. Ringer's solution, 0.9% sodium chloride solution, or 5% dextrose solution can be used as a solvent. The volume of solvent depends on the required final concentration of azithromycin. To obtain a solution of 1 mg/ml, 500 ml of solvent is required, 2 mg/ml - 250 ml. The prepared solution is used immediately (provided that there are no visible undissolved particles, if any are found, the solution cannot be used).

Recommended doses and duration of treatment for adult patients:

  • community-acquired pneumonia: 500 mg once a day for 2 days (by doctor’s decision, the course can be extended to 5 days), then the patient is transferred to the oral form of Sumamed at a dose of 500 mg once a day; the general course of treatment is 7–10 days;
  • infectious and inflammatory diseases of the pelvic organs: 500 mg once a day for 2 days (maximum - up to 5 days), then once a day 250 mg of Sumamed in dosage form for oral administration; The general course of treatment is 7 days.

Patients with mild to moderate renal and/or liver dysfunction, as well as the elderly, do not require dose adjustment.

Side effects

  • gastrointestinal tract, liver and biliary tract: very often – diarrhea; often – abdominal pain, vomiting, nausea; uncommon – belching, dry mouth, dyspepsia, dysphagia, hepatitis, increased salivation, ulcers of the oral mucosa, constipation, flatulence, gastritis, bloating; rarely – cholestatic jaundice, liver dysfunction; very rarely - pancreatitis, change in tongue color; frequency unknown - liver necrosis, liver failure, fulminant hepatitis;
  • respiratory system: infrequently – nosebleeds, shortness of breath;
  • cardiovascular system: infrequently - flushing of the face, palpitations; frequency unknown - ventricular tachycardia, decreased blood pressure, pirouette-type arrhythmia, prolongation of the QT interval;
  • nervous system and sensory organs: often – headaches; uncommon – taste disturbance, nervousness, insomnia or drowsiness, dizziness, paresthesia, visual impairment, vertigo, hearing impairment; rarely – pronounced emotional arousal; frequency unknown - loss or distortion of smell, psychomotor hyperactivity, delirium, loss of taste, anxiety, hallucinations, hypoesthesia, fainting, myasthenia gravis, aggression, convulsions, tinnitus and/or hearing impairment;
  • musculoskeletal system: uncommon – muscle pain, neck and back pain, osteoarthritis; frequency unknown – arthralgia;
  • skin and subcutaneous tissues: uncommon – dry skin, skin rash, sweating, dermatitis; rarely - increased photosensitivity; frequency unknown - erythema multiforme, Stevens-Johnson syndrome;
  • genitourinary system: infrequently - metrorrhagia, pain in the kidneys, dysuria, testicular dysfunction; frequency unknown - acute renal failure, interstitial nephritis;
  • metabolism: infrequently – anorexia;
  • lymphatic system and blood: uncommon – neutropenia, eosinophilia, leukopenia; very rarely - hemolytic anemia, thrombocytopenia;
  • allergic reactions: uncommon – hypersensitivity reactions, angioedema; frequency unknown - anaphylactic reactions;
  • infectious diseases: uncommon – pharyngitis, rhinitis, pneumonia, respiratory diseases, gastroenteritis, candidiasis; frequency unknown – pseudomembranous colitis;
  • laboratory parameters: increased activity of liver enzymes, increased plasma concentrations of bilirubin, urea, creatinine, glucose and chlorine, decreased or increased concentration of bicarbonates, increased hematocrit, increased alkaline phosphatase activity, changes in sodium and potassium content in plasma, increased number of eosinophils, monocytes, platelets , basophils and neutrophils, decrease in the number of lymphocytes;
  • other reactions: uncommon - facial swelling, malaise, peripheral edema, asthenia, chest pain, feeling tired, fever.

special instructions

If you miss the next dose of Sumamed, you should take the missed dose as soon as possible, subsequent doses are taken at intervals of 24 hours.

During treatment with the drug, regular examination of the patient for the presence of non-susceptible pathogens and signs of superinfections, including fungal ones, is required.

If antibiotic-associated diarrhea develops during therapy with Sumamed and 2 months after the end of treatment, it is necessary to exclude pseudomembranous colitis.

Information for patients with diabetes mellitus and patients on a diet: the powder for the preparation of the suspension contains sucrose (0.32 bread units/5 ml).

Information for patients on a diet with limited sodium intake: one bottle of Sumamed in the form of a lyophilisate contains 198.3 mg of sodium.

When antacids are prescribed simultaneously, oral forms of Sumamed should be taken 1 hour before or 2 hours after the use of these drugs.

If side effects from the central nervous system or organ of vision occur, care must be taken when driving vehicles and other potentially dangerous mechanisms.

Drug interactions

Due to the high pharmacological activity of azithromycin and the significant likelihood of interaction of the drug Sumamed with other drugs/substances, only the attending physician can give recommendations on their compatibility.

Terms and conditions of storage

Store at a temperature not exceeding 25 °C. Keep away from children.

Shelf life: film-coated tablets, dispersible tablets and capsules – 3 years; powder for the preparation of a suspension for oral administration and lyophilisate for the preparation of a solution for infusion - 2 years.

Sumamed por. d/susp.internal 100mg/5ml/23ml 17g 50ml n1

Sumamed powder 100 mg/5 ml

Sumamed 100mg/5ml 20.925g powder for injection. suspensions for internal use 20ml bottle 50ml

Sumamed powder for suspension 100 mg/5 ml 20 ml strawberry

Sumamed tablets 125 mg 6 pcs.

Sumamed forte powder 200 mg/5 ml 16.74 g

Sumamed 125mg No. 6 tablets

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

In the UK there is a law according to which a surgeon can refuse to perform an operation on a patient if he smokes or is overweight. A person must give up bad habits, and then, perhaps, he will not need surgical intervention.

Scientists from Oxford University conducted a series of studies in which they came to the conclusion that vegetarianism can be harmful to the human brain, as it leads to a decrease in its mass. Therefore, scientists recommend not completely excluding fish and meat from your diet.

When we sneeze, our body stops working completely. Even the heart stops.

Human bones are four times stronger than concrete.

Most women are able to derive more pleasure from contemplating their beautiful body in the mirror than from sex. So, women, strive to be slim.

Regular use of a solarium increases your chance of developing skin cancer by 60%.

Many drugs were initially marketed as medicines. Heroin, for example, was originally brought to market as a cure for children's coughs. And cocaine was recommended by doctors as an anesthesia and as a means of increasing endurance.

People who eat breakfast regularly are much less likely to be obese.

An educated person is less susceptible to brain diseases. Intellectual activity promotes the formation of additional tissue that compensates for the disease.

A job that a person doesn’t like is much more harmful to his psyche than no job at all.

In an effort to get the patient out, doctors often go too far. For example, a certain Charles Jensen in the period from 1954 to 1994. survived more than 900 operations to remove tumors.

Four pieces of dark chocolate contain about two hundred calories. So if you don’t want to gain weight, it’s better not to eat more than two slices a day.

Research shows that women who drink several glasses of beer or wine per week have an increased risk of developing breast cancer.

Even if a person's heart does not beat, he can still live for a long period of time, as the Norwegian fisherman Jan Revsdal demonstrated to us. His “engine” stopped for 4 hours after a fisherman got lost and fell asleep in the snow.

Over the course of a lifetime, the average person produces no less than two large pools of saliva.

An infectious inflammatory process in the kidneys associated with the development of bacteria in the urinary system is called pyelonephritis. This serious illness is observed in...

Source: http://www.neboleem.net/sumamed.php