Flemoxin solutab for what day does it help?

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Flemoxin is a well-known antibiotic in an innovative form

Flemoxin is a generic version of one of the most popular antibiotics in the world - Amoxicillin. The original drug was developed by British pharmacists in the 60s of the last century.

Table of contents:

Amoxicillin appeared on the pharmaceutical market in the early 70s.

Before you continue reading: If you are looking for an effective method of getting rid of a runny nose, pharyngitis, tonsillitis, bronchitis or colds, then be sure to look at this section of the site after reading this article. This information has helped so many people, we hope it will help you too! So, now back to the article.

Amoxicillin is, without a doubt, one of the safest broad-spectrum antibacterial drugs. According to some reports, this penicillin antibiotic is almost the most prescribed medicine in pediatrics. Almost every reputable pharmaceutical company considers it its duty to release its own Amoxicillin. The Japanese corporation Astellas Pharma also succeeded in this matter by developing Flemoxin.

Flemoxin Solutab stands out from the monotonous background of Amoxicillins due to its release form. After all, the drug is available in the form of dispersible tablets, which have many advantages compared to the pills we are used to.

In this article we will try to understand how Flemoxin differs from its analogues, and also clarify the positive aspects of the drug. And let’s not ignore the negative qualities, which, of course, are also present.

Astellas Pharma: new life for antibiotics

Astellas Pharma is the largest Japanese pharmaceutical concern. It appeared in 2005 thanks to the merger of two well-known Japanese companies: Fujisawa Pharmaceutical Co and Yamanouchi Pharmaceutical Co.

Today, Astellas Pharma works in various areas of medicine, creating both original drugs and analogues of well-known brands. The company also produces several antibiotics, which have become widely known due to their dispersible form.

Each of these medicines has an additional word in the name indicating a special form - solutab. Dispersible drugs include:

  • cephalosporin antibiotic Ceforal solutab;
  • Unidox Solutab, widely known in Russia;
  • Vilprafen solutab;
  • Flemoxin Solutab and Flemoklav Solutab are two related drugs containing Amoxicillin as the active ingredient.

I would like to note that Flemoxin Solutab is registered only in Germany, Iceland, Portugal and the CIS countries.

Flemoxin solutab: composition of the drug

So, Flemoxin contains, as you already understood, the only active component - Amoxicillin - in the form of a stable compound (trihydrate).

Amoxicillin is a semi-synthetic penicillin, which in its chemical structure and spectrum of activity is very similar to Ampicillin.

As additional substances, Flemoxin contains chemical substances, which, in fact, ensure its solubility in a minimum volume of solvent. These include cellulose and MCC - microcrystalline cellulose.

Note that Flemoxin tablets have a pleasant citrus taste due to the addition of tangerine and lemon flavoring.

The color of the tablet can vary from pure white to yellowish or even light yellow. A change in color does not mean that the drug was stored incorrectly. Or, moreover, it is a crude fake. The color variations of Flemoxin are associated with the presence of cellulose compounds in it, in which color changes are allowed.

Forms of release of Flemoxin - for both children and adults

The wide range of Flemoxin includes both children's and adult forms of release, which differ only in dosage.

Unlike conventional oral antibiotics, Flemoxin is not presented in powder form for the preparation of a children's suspension. Therefore, parents of young patients are practically deprived of the opportunity to show their hidden pharmaceutical abilities, calculating the volume of water and diluting the white powder with trembling hands.

So, let’s list the release forms of Flemoxin Solutab.

Children's release forms:

  • Flemoxin solutab dosage 125 mg;
  • Flemoxin solutab at a dose of 250 mg.

Adult release forms:

  • Flemoxin solutab 500 mg;
  • Flemoxin solutab at a dose of 1000 mg.

Why can’t you split a Flemoxin tablet?

The oblong tablet of Flemoxin has a cross mark. Most patients believe that the score is needed in order to split the tablet in half. And get a dosage exactly half the original one.

I would like to explain to readers why experts persistently warn patients against such a division.

There may be two reasons why you should not divide the tablet into two parts. Firstly, many tablets are coated with a protective coating that protects them from the destructive properties of hydrochloric acid. However, this does not apply to Flemoxin - it is not coated, so we can go further.

The second and main reason is that when dividing a tablet, it is technically impossible to find out the dosage of the resulting parts. Even if you have a pharmacy scale at hand, and you were able to absolutely accurately divide a 1000 milligram tablet of Flemoxin into two equal parts, the amount of the active substance remains unknown. Why do you think?

Take another look at the drug packaging or instructions for Flemoxin. The composition of any tablet drug (as, by the way, most others) often contains many other substances in addition to the main active component. Using the example of Flemoxin Solutab at a dosage of 125 mg, we see that the content of cellulose, microcellulose (or MCC), as well as flavorings and saccharin is about 17% of the share of Amoxicillin. In this case, the active substance is distributed unevenly, and therefore the left half of the tablet may contain N percent more active substance than the right half. Or vice versa.

Accordingly, the effectiveness of different parts of the Flemoxin tablet may, to put it mildly, be different. And side effects too.

Now let’s remember that we are not dealing with ascorbic acid vitamins, but with a drug, the dose of which is carefully selected depending on age and the severity of the infection. And let’s remember the unshakable rule of pharmaceuticals: dividing a tablet in order to reduce the dosage is simply prohibited!

Exceptions may include some cardiac medications. In such cases, the manufacturers themselves take into account all the nuances and technologically achieve uniform distribution of all the components of the tablet.

Dispersible tablet: what is it?

Many patients, when they first encounter the name “dispersible tablet,” have difficulty imagining what it is. Meanwhile, more and more pharmaceutical companies are trying to put older drugs into dispersible form. Dispersible vitamins, antibiotics, and even erectile dysfunction drugs are appearing on the market.

Dispersible tablets were originally created for patients who had difficulty swallowing. This condition, which is medically called dysphagia, occurs in 35% of the general population and in 60% of older people.

The first dispersible tablets dissolved in the mouth to produce gas. Subsequently, new forms were developed, which included cellulose and its compounds. We have already mentioned that Flemoxin solutab is one of these drugs.

Advantages of dispersible form

So, let's figure out how Flemoxin dispersible tablets differ from regular Amoxicillin and what their advantage is.

So, the dispersible form of Flemoxin:

Flemoxin dispersible tablets are absorbed in the oral cavity directly into the blood, bypassing the gastrointestinal tract. Due to this, the bioavailability of orally soluble tablets is an order of magnitude higher than that of oral tablets;

  • quickly reaches peak concentration.

Oral tablets begin to be absorbed into the blood within 15–20 minutes after administration, at best. Dispersible dosage forms (including Flemoxin) are absorbed within 5 minutes after dissolving in the mouth;

  • more convenient for pharmaceutical substances that are unstable in water.

An excellent example is children's Flemoxin Solutab 125 mg, which is much more convenient in the form of soluble tablets than Amoxicillin suspension;

  • can be used for newborns and infants;
  • does not require additional manipulations before use, unlike, for example, a suspension that needs to be prepared;
  • may be dissolved in breast milk;
  • Requires very little water to dissolve.

Every parent knows how important it is that the medicine is not only effective, but also tasty. A mother who is trying to pour the hated bitter medicine into a sick child while the father is holding the child by the arms and legs is a very sad picture. And not that rare.

Astellas Pharma pharmacists masked the traditionally bitter taste of Amoxicillin with citrus flavors and saccharin. Therefore, Flemoxin Solutab is a tasty medicine for children.

Flemoxin pharmacokinetic data provide convincing evidence of its benefits

The pharmacokinetic properties of drugs largely determine their effectiveness. This is an axiom that does not require proof.

For example, one of the most negative aspects of Flemoxin’s predecessor, Ampicillin, is low absorption and short half-life. Imagine that two-thirds of the antibiotic is not absorbed at all. That is, you drink one gram of a drug that is not the safest, but only 300 mg enters the blood. The remaining part is excreted from the body, simultaneously “working” in the intestines on your previously quite viable microflora. Not the most pleasant prospect, is it?

Therefore, one of the main tasks of modern pharmaceuticals is the search for new drugs and forms that have a high level of bioavailability. And Flemoxin Solutab, without any doubt, can be called one of these drugs.

Flemoxin is absorbed into the blood very quickly - within 5-10 minutes - and almost completely. The bioavailability of dispersible Amoxicillin is close to 93%. Note that for oral dosage forms such figures are practically record-breaking. In comparison with oral Amoxicillin, Flemoxin also clearly wins in this indicator. Thus, the bioavailability of conventional tablet forms of Amoxicillin rarely exceeds 75-80%.

Flemoxin packaging: tightness is a condition of preservation

Flemoxin dispersible tablets are extremely sensitive to moisture. To protect the tablet from moisture in the air, it is necessary to ensure that the packaging is completely sealed. Flemoxin is packaged in aluminum blisters, which guarantee protection of the antibiotic from premature decomposition.

If you accidentally squeezed a Flemoxin tablet out of the cell, it is better to either take it immediately or dispose of it, that is, mercilessly throw it in the trash.

It should be remembered that due to the high cellulose content, there is a possibility of gradual dissolution of the tablet in air moisture. And we know that any antibiotic, including Flemoxin, is unstable in a dissolved state.

Therefore, a Flemoxin tablet that was stored in damaged packaging or, even worse, without it, may turn out to be, at best, a harmless dummy.

Flemoxin solutab: spectrum of pharmacological activity

Amoxicillin, the active ingredient in Flemoxin, is active against many gram-positive and gram-negative bacteria. Among them:

  • streptococci - Streptococcus pyogenes and Streptococcus pneumonia;
  • staphylococci, including Staphylococcus aureus;
  • clostridia;
  • gonorrhea pathogens Neisseria gonorrhoeae;
  • listeria;
  • causative agent of peptic ulcer Helicobacter pylori.

Low activity of Flemoxin is recorded against most pathogens of intestinal infections:

And finally, Proteus, Enterobacteriaceae, and microorganisms that produce beta-lactamases are absolutely insensitive to the action of Flemoxin.

Beta-lactamases and Flemoxin: a fight for life

In the instructions for Flemoxin and other penicillin, as well as cephalosporin antibiotics, the term “beta-lactamase” is often used. Usually, patients who carefully study the annotations intuitively understand that lactamase is probably something very bad. But it is not always possible to clearly understand what it is and what, exactly, the harm of beta-lacatmaz is.

Let's try to find out who or what this beta-lactamase is. Let's start by remembering when the first penicillins began to be used.

The history of antibiotics goes back more than 70 years. During this period, many microorganisms learned to recognize the destructive antibacterial substance. Modern strains of bacteria already synthesize antidotes for at least two groups of antibiotics—penicillins and cephalosporins. The role of “antidote” is played by special enzymes from the group of beta-lactamases (penicillinases), which destroy the beta-lactam ring of the antibiotic. As a result, the drug is completely inactivated and has no antibacterial effect.

The first bacteria that learned to produce penicillinase were staphylococci. And, if in 1944 only 5% of Staphylococcus aureus strains produced the enzyme, now this figure has increased many times and is almost 90%!

In addition, bacteria that produce beta-lactamase include streptococci, as well as many gram-negative microorganisms, including Klebsiella, Enterobacteriaceae, Pseudomonas and other pathogens.

So, when infected with microorganisms that produce beta-lactamases, neither Flemoxin, nor other analogues of Amoxicillin, nor Ampicillin are absolutely effective.

Therefore, a correct assessment by a doctor when prescribing unprotected penicillins is so important. The specialist’s task is to differentiate the pathogen and “not to miss” in choosing an antibiotic.

Flemoxin or Flemoklav, which is better?

The Astellas Pharma company produces another antibiotic containing Amoxicillin, Flemoclav. Both the name and packaging of the drug are very similar to Flemoxin, however, there is a significant difference between these drugs. Let's figure out how these seemingly similar antibiotics differ.

We have already found out that some strains of microorganisms produce beta-lactamase, which inactivates Flemoxin. Therefore, for many infectious diseases, Amoxicillin, the active ingredient in Flemoxin, is absolutely ineffective.

Researchers from the British company Beecham, which developed Amoxicillin, have managed to find a substance that blocks beta-lactamases. This substance turned out to be clavulanic acid. Scientists have proven that the combination of clavulanic acid and penicillin antibiotics is effective against strains of bacteria that produce beta-lactamase.

This is how a new antibacterial drug with an extended spectrum of action appeared. The original antibiotic was released by Glaxo under the name Augmentin. By the way, thanks to the protective effect of clavulanates, complex antibiotics began to be called protected. After all, clavulanic acid really serves as a real protection for the lactam penicillin ring from destruction!

The Japanese corporation Astellas Pharma has developed a dispersible form of protected Amoxicillin - Flemoklav.

Patients often wonder: which antibiotic is preferable - Flemoxin or Flemoklav? Only a specialist who relies not only on theoretical, but also on practical knowledge can resolve this dilemma.

When deciding on the selection of a particular antibiotic, the doctor evaluates the history of the current disease, as well as experience in treating previous infections. The most important stage in selecting an antibiotic is differentiation of the pathogen. An error leads to incorrect prescription of the drug, and, therefore, to ineffective treatment.

Making a decision is complicated by the fact that in the vast majority of cases the pathogen is calculated empirically, that is, based on the symptoms of the disease. A qualified doctor will undoubtedly be able to do this. But a medical amateur is definitely not able to do this. Therefore, patients should remember: the decision to prescribe antibiotics and the choice of a specific drug should be entrusted to the doctor or clinical pharmacist. And no one else!

Flemoxin solutab: when to take?

Indications for the use of Flemoxin are primarily related to the spectrum of pharmacological activity of the drug. Note that Amoxicillin is included in the treatment protocols for many infectious diseases.

Modern semi-synthetic penicillin - Flemoxin solutab - is the drug of choice for uncomplicated pathologies of the respiratory tract of bacterial origin. I would like to place special emphasis on the word “uncomplicated”. In case of a moderately severe disease or a severe, complicated course of infection, protected penicillins or antibiotics of other groups are preferred to Flemoxin.

So, let's list the main diseases for which Flemoxin Solutab is indicated:

- acute otitis media - inflammation of the middle ear.

In the initial treatment of acute otitis media, Flemoxin is the first-line drug, that is, the preferred antibiotic. However, if the disease is aggravated by severe otalgia (ear pain), a temperature above 39 degrees, then the doctor may suspect infection with beta-lactamase producing strains of Haemophilus influenzae and Moraxella catarrhalis. In such cases, the drug of choice is Flemoclav, that is, protected Amoxicillin.

- pharyngitis and tonsillitis - inflammation of the mucous membrane of the pharynx and tonsils.

As a rule, these diseases are caused by Streptococcus pyogenes, which are highly sensitive to Amoxicillin. Standard treatment protocols indicate that for bacterial tonsillitis Flemoxin solutab is the drug of choice. However, if the disease is recurrent in nature, that is, it recurs periodically over, for example, one year, then preference is given to a combination with clavulanates, as well as macrolides or cephalosporins.

- lower respiratory tract infections.

The main causative agents of pneumonia and bacterial bronchitis - alpha and beta hemolytic streptococci, Streptococcus pneumoniae, Staphylococcus aureus and Haemophilus influenzae - are sensitive to Flemoxin. Therefore, for uncomplicated bronchitis and pneumonia, Flemoxin Solutab can be used.

- skin infections caused by sensitive streptococci, Staphylococcus aureus and Escherichia coli.

- urinary tract infections.

Flemoxin is effective for inflammatory diseases of the kidneys and bladder if they are caused by sensitive enterococci Enterococcus faecalis, Escherichia coli or Proteus. For the treatment of uncomplicated urinary tract infections caused by enterococcus, Flemoxin is the drug of choice.

However, it is worth considering that some strains of E. coli are resistant, that is, completely insensitive to Amoxicillin. Meanwhile, cystitis - inflammation of the bladder - in most cases is caused by E. coli. Therefore, Flemoxin is prescribed with caution for urological infections.

- typhoid fever and salmonellosis.

Flemoxin is considered an alternative antibiotic for these infections and is used when first-line drugs are contraindicated. Note that the drugs of choice are fluoroquinolone antibiotics and third-generation cephalosporins.

Flemoxin is used in cases of early localized Lyme disease.

Treatment of peptic ulcer with Flemoxin

Long gone are the days when peptic ulcer disease was considered an incurable chronic disease that truly aggravated the patient’s life. Ulcer sufferers no longer need to be teetotalers, drink potato juice on an empty stomach, or poison themselves with vinylin. And especially to lie down on the operating table.

Thanks to the discovery of the role of a banal infection in the formation of ulcers in the wall of the stomach or duodenum, quick and effective therapy for these diseases has become possible. Helicobacter pylori infection, the causative agent of which is the microorganism Helicobacter pylori, is the cause of peptic ulcer disease in almost 90% of cases. In addition, Helicobacter provokes the development of atrophic gastritis, a dangerous inflammatory disease of the stomach wall, which is a risk factor for ulcers and even stomach cancer.

For a long time, scientists could not even imagine that anything living could survive in a highly hydrochloric acid environment. It turned out that Helicobacter pylori not only survives, but also actively reproduces. The bacterium synthesizes a special enzyme that neutralizes the hydrochloric acid of the stomach - that’s the whole secret of survival.

Meanwhile, Helicobacter responds well to therapy. The complex treatment regimen for the infection includes two antibacterial drugs (one of which is Flemoxin), as well as a proton load inhibitor. The last medicine is necessary in order to completely neutralize hydrochloric acid in the stomach. Otherwise, healing of the inflamed area is simply impossible.

So, one of the most effective treatment regimens for peptic ulcer disease includes Amoxicillin (Flemoxin Solutab), Clarithromycin and a proton pump inhibitor (for example, Omeprazole, Lanzaprozole and other drugs). If you are intolerant to Clarithromycin, use a two-component regimen or add Metronidazole as an antimicrobial agent.

STD treatment

The abbreviation STD hides not the most pleasant diseases - diseases that are sexually transmitted.

Flemoxin is used only for two infections, and only in special cases. Let's look at them in more detail:

Amoxicillin was previously widely used to treat uncomplicated cases of gonorrhea. But recently, penicillin-resistant strains of Neisseria gonorrhoeae have emerged, so Flemoxin is often replaced with another antibiotic.

Flemoxin is a first-line treatment for uncomplicated urethritis (inflammation of the urethra) and cervicitis (inflammation of the cervical canal) during pregnancy. Note that in most cases of chlamydia in pregnant women, instead of Flemoxin or other Amoxicillin, Sumamed is still used, which is considered the drug of choice.

Flemoxin is usually prescribed in case of individual intolerance to macrolides.

Standard dosages of Flemoxin according to the instructions for use

Let us immediately emphasize that any antibacterial drug is dosed individually. And Flemoxin is no exception to the rule. In each specific case, the doctor assesses the severity of the disease, medical history, that is, medical history, as well as concomitant diseases. And based on this information, he selects the correct dosage.

However, there are still standard dosages of Flemoxin - something like the average body temperature in the ward. We emphasize that they are necessary for the doctor, not for the patient. And even more so, you should not rely on this information in order to prescribe the most correct treatment regimen for yourself.

So, according to the instructions for use of Flemoxin, the following dosages are recommended:

  • For children from 1 to 3 years old, Flemoxin 250 mg tablets are used twice a day. An alternative prescription may be 125 mg of Flemoxin three times a day at regular intervals;
  • The maximum dose of Flemoxin for a child is 60 mg per kilogram of weight per day. This dosage is indicated for severe infectious processes;
  • for children from 3 to 10 years old, 375 mg of Flemoxin is prescribed twice or 250 mg three times a day;
  • for children over 10 years of age and adults, the average dosage of Flemoxin is 500–750 mg twice or 375–500 mg three times a day.

For severe infections, Flemoxin can be used up to 3 grams per day, certainly divided into three doses.

The duration of treatment, as well as the dosage of Flemoxin, is selected individually. Please note that the minimum course of therapy should not be less than five days. The standard treatment regimen consists of a weekly course of antibiotics. If the infection is caused by the streptococcus Streptococcus pyogenes, Flemoxin is used for at least 10 days.

It is worth emphasizing that antibiotic treatment should not be stopped immediately after the symptoms of the disease disappear. This haste is fraught with the formation of resistant strains from among selected and strong bacteria, on which Flemoxin simply does not have time to act.

In order to avoid complications, it is necessary to continue treatment with Flemoxin for two days after the manifestations of the infection stop. At the same time, we must not forget that the minimum course should not be less than five days.

Chew, swallow, dissolve, or what is the best way to take Flemoxin?

When encountering dispersible tablets for the first time, many patients wonder what is the best way to take Flemoxin. We will try to answer this question and clarify whether there is a difference between the methods of taking this drug.

So, one of the most significant advantages of Flemoxin Solutab is the ability to choose a method of use that is convenient for the patient.

Depending on the individual characteristics and personal preferences of each Flemoxin tablet, you can:

  • chew in the mouth;
  • suck like a lollipop;
  • dissolve in a small amount of cool boiled or simply purified water;
  • dissolve in breast milk - for infants;
  • dissolve in any juice, compote, tea and other drink. The only condition is that the drink should not be hot.

Let us immediately note that there is no fundamental difference in the methods of application. The rate of absorption, bioavailability and metabolism of Flemoxin do not depend on how long you chewed the tablet or how much juice you diluted in.

In addition, the pharmacokinetic properties of Flemoxin are not affected by food intake. You can take the tablet before meals, during lunch or after dinner, and in all cases the bioavailability of the antibiotic will be the same.

Contraindications to taking Flemoxin

Do not forget that Flemoxin is an antibacterial drug that has side effects and contraindications. However, in fairness, it is worth noting that Amoxicillin is one of the safest antibiotics.

So, we list the absolute contraindications to taking Flemoxin:

- individual sensitivity to penicillin antibiotics.

The likelihood of an allergic reaction to Flemoxin is low. However, if you are allergic to medications, especially antibiotics, do not forget to warn your doctor about this. A specialist will be able to assess the risk and choose the right antibacterial agent.

In addition, do not forget about cross-sensitivity between penicillins and cephalosporins. If you have had an allergic reaction, for example, to ceftriaxone or any other antibiotic from the cephalosporin group, then it is also better to replace Flemoxin.

Erroneous prescription of Flemoxin and other penicillins for this disease leads to the appearance of an erythematous rash. Note that the symptoms of infectious mononucleosis are similar to those of bacterial pharyngitis and tonsillitis. However, mononucleosis is caused by a virus and does not require antibiotic treatment. Only a doctor can make the correct diagnosis and prescribe the correct medication.

Flemoxin during pregnancy: risks and benefits

Flemoxin is one of the antibiotics conditionally approved for use during pregnancy. The instructions for Flemoxin indicate that the drug can be used in cases where the risk to the child is less than the expected benefit to the mother.

Don't be afraid of this wording. It is caused solely by the fact that clinical trials of Flemoxin on pregnant women have not been carried out, and it is unlikely that they will ever be carried out for obvious reasons.

Nevertheless, Flemoxin is considered one of the safest antibiotics that can be used during pregnancy. And quite a long experience of using it is excellent proof of this. But let us emphasize once again that any antibiotic, including Flemoxin, can only be prescribed by a doctor. Think about your health and the health of your unborn child.

Side effects associated with treatment with Flemoxin

Flemoxin is one of the antibiotics that is well tolerated. However, there is a possibility of adverse events during or after treatment with the drug. Among them:

in 1-10% of cases the following are registered:

  • development of vulvovaginal fungal infection (in 2% of patients). In such situations, during treatment with Flemoxin, parallel use of antifungal drugs, for example, Fluconazole, is recommended;
  • diarrhea (in 1.7% of patients). As a rule, this symptom does not require discontinuation of Flemoxin and goes away on its own;
  • nausea (in 1.3% of patients);
  • headache (in 1% of cases).

in less than 1% of cases the following are possible:

In less than 1% of cases treated with Flemoxin, a rather serious side effect may develop - pseudomembranous colitis. The cause of this condition is a change in the composition of the intestinal flora and the proliferation of opportunistic microorganisms Clostridium difficile. Clinically, pseudomembranous colitis is manifested by severe diarrhea, which is fraught with general dehydration of the body.

When such symptoms appear, the first thing the patient should do is to immediately notify the attending physician. Usually in such cases, the only possible solution is to discontinue Flemoxin and prescribe another antibiotic or antimicrobial drug to which clostridia are sensitive. In addition, restoring the water-salt balance in the body plays an important role.

Flemoxin solutab - analogues

The pharmaceutical market is replete with generics of Amoxicillin from a variety of manufacturers. Let's try to list those Flemoxin analogues that have earned positive reviews from doctors:

  • Amoxicillin produced by the Serbian company Hemofarm;
  • Amoxicillin Sandoz, which is produced by the French corporation Sandoz;
  • Hiconcil, a drug from the Slovak company KRKA;
  • Ospamox produced by the Austrian pharmaceutical concern Biochemi;
  • Amosin, Russian pharmaceutical company Synthesis.

Despite the abundance of analogues of Flemoxin Solutab, very few drugs have the same dispersible form. These include the Austrian Ospamox DT.

And the last thing I would like to note. Despite the wide selection of Flemoxin analogues, one should not forget that the prerogative of both prescribing an antibiotic and selecting a generic belongs exclusively to the doctor.

The article above and comments written by readers are for informational purposes only and do not encourage self-medication. Consult a specialist regarding your own symptoms and illnesses. When taking any medicine, you should always use the instructions that come with the medicine and your doctor's advice as a guide.

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It is also worth paying attention to other medications:

I didn’t notice any side effects: we didn’t have diarrhea, although we didn’t take Linex. The doctor said that Flemoxin does not cause dysbacteriosis, and he was right.

Be careful! Especially with children!

By the way, having exceeded the dose of the drug (it happened (((, severe cough with vomiting, I thought that the drug was not absorbed and repeated taking the medicine again.) we were covered with a rash, recalculated the dose for that day and that’s it, the rash went away and we were treated for 5 days.

Mother of two sons (2.5 and 5 years old).

Repeated use caused anaphylactic shock. Pale face, blue lips, leg and arm cramps, respiratory arrest and loss of consciousness. Unfortunately, there are doctors who “earn their living” in front of drug companies, without thinking about the life and safety of young patients.

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Flemoxin Solutab: instructions for use for adults and children

This bactericidal agent belongs to the semi-synthetic penicillins. Effective against all kinds of microorganisms, including gram-negative ones (capable of resisting the action of antibiotics for a long time). The active substance, amoxicillin trihydrate, makes up 50% of the weight of the drug. In addition to it, the components are microcrystalline and dispersed cellulose, crospovidone, magnesium stearate, as well as flavoring additives.

Release form

The manufacturer produces Flemoxin in the form of white or light yellow tablets. Weighing 125, 250, 500 and 1000 mg, with engraving, respectively: 231, 232, 234, 236. The price in pharmacies depends on the size of the portions and ranges from 240 to 480 rubles. One package contains 20 tablets. Manufacturer: Japanese company Astellas. The medicine should be stored at a temperature of 15–25 °C.

Pharmacological action of the drug

Flemoxin prevents bacteria from creating cell membranes by blocking the main component of synthesis - peptidoglycan. This medication is quickly absorbed in the gastrointestinal tract. The convenience of its use is associated with the possibility of freely eating, even at the same time as the medicine, this will not affect the effect. Like any antibiotic, Flemoxin can only be used in accordance with a prescription prescribed by a doctor.

The effect of the medication begins soon after use, and reaches its maximum after an hour and a half. Taking 1000 mg of Flemoxin brings the concentration of the active substance in the blood to 8 mcg/l, in the gall bladder fluid - 25 mcg/l, in amniotic fluid during pregnancy - 2.5 mcg/l. These numbers increase in proportion to the dose.

A fifth of the active component interacts with blood proteins. The accumulation of the drug occurs in the internal membranes of hollow organs, bone tissue, fluid of the eye chambers, as well as in mucous secretions from the respiratory tract and lungs. The remainder of the substance continues to act in the body, creates additional protection against infection and speeds up recovery.

The therapeutic compound does not pass through the BBB (barrier between the circulatory system and the central nervous system). But with meningitis, it enters the cerebrospinal fluid in sufficient quantities.

The half-life of the drug in adults is from one to one and a half hours, in newborns and infants it is 3 times longer. 90% of the substance leaves the body within 8 hours, of which two thirds are excreted in the urine. Most of the metabolic products of amoxicillin have no effect on the body.

What does it help with?

Flemoxin successfully fights against various types of streptococci, tetanus and Haemophilus influenzae, Moraxella, Listeria, Helicobacter pylori. Can be used against fecal enterococcus, Proteus mirabilis, Salmonella (causing typhoid fever), Shigella Sonne, Vibrio cholerae. Does not affect microorganisms capable of synthesizing beta-lactamase. These include Pseudomonas aeruginosa, some Proteus, and Enterobacteriaceae.

  • Bronchial, tracheal and pulmonary diseases. For example, flu, sinusitis, sinusitis.
  • Inflammatory pathologies of the kidneys (pyelonephritis), bladder (cystitis), skin (furunculosis, streptoderma, erysipelas), bone tissue (osteomyelitis), and gastrointestinal tract.
  • Some gynecological diseases (adnexitis).
  • Together with other medications, it helps to cope with infectious mononucleosis, blood poisoning, and abscesses.
  • Used after surgery to prevent complications.

How to take for adults

The individual dosage is influenced by factors such as the severity of the disease, the susceptibility of this type of microorganism to the drug, and the age of the patient. An adult takes 1000–4000 milligrams of medication per day in two servings.

The course of treatment for mild to moderate infections lasts no more than a week. This period increases to 10 days for streptococcal infection. If the disease has subsided, you can stop taking it only on the third day after the symptoms disappear.

How to take for children

Children's dosage is calculated based on body weight. For each kilogram, about 40 mg of the substance per day is required for moderate severity of the disease and up to 180 for complications. A child over 10 years old should be given two servings of 500 or 1000 milligrams. For younger children, doses of 250 mg are used, taken 3 times a day. Children 1–3 years old are given 125 milligrams three times a day.

Tablets are taken both before and after meals. The way they enter the body can be either swallowing whole, chewing with a glass of water, or preparing a syrup or suspension. The soluble form of Solutab is convenient for its pleasant taste (thanks to the lemon-tangerine filler) and rapid absorption.

Dosage regimen for angina

This disease is caused by staphylo- and streptococci, very resistant microorganisms. Only some antibiotics can effectively destroy them. A sore throat is accompanied by symptoms similar to a cold: high fever, sore throat, chills, weakness.

A study that reveals the sensitivity of pathogenic flora to medications requires time, which may not be available in the case of an acute form of the disease. Flemoxin would be a good solution, since it acts quickly, is universal and has mild side effects (compared to other bactericidal agents).

Children over 10 years of age and adults need to take about a milligram of medication in two servings per day. It is better to dissolve the product in water; the child will readily drink this suspension with a pleasant smell. Inhalations will help as an additional way to relieve inflammation.

The course of treatment for mild to moderate infections lasts no more than a week. In cases where no improvement is observed within two days, the doctor should prescribe another antibiotic. After recovery, it is recommended to undergo probiotic therapy to restore the natural balance of microorganisms in the intestines.

Dosage regimen for sinusitis

This disease is an inflammation of the air-filled cavities connected to the nose. Symptoms: chills, fever, mucus and purulent discharge, pressure in the bridge of the nose, headache when bending or clenching the teeth. If left untreated, this disease can become chronic and cause vision problems, otitis, meningitis, periostitis, systemic inflammation of the body (sepsis).

The disease can be caused by bacteria, viruses, fungi, and allergic reactions. The presence of pus highly likely indicates a microbial source of infection. It is in the case of a bacterial infection that the antibiotic is extremely effective. If the disease is caused by fungi, its use is contraindicated, and it has no effect on viruses. The instructions for use advise taking 2000–3000 milligrams of the medicine in two servings. The allergic form of sinusitis, as well as sometimes the viral form, go away on their own.

Reception for cystitis

A common bladder disease can also be effectively treated with Flemoxin. In terms of the frequency of occurrence of the pathology, women and girls are in first place, children are in second; men are rarely infected with cystitis. Since inflammation of the bladder walls is caused by bacteria, antibiotic therapy becomes indispensable. It is recommended to take two tablets of Flemoxin Solutab 500 mg or 1000 mg per day.

Since cystitis can also be caused by bacteria that are insensitive to the product, it is necessary to do a urine test to identify the pathogen. In some cases, the sources of the disease are viruses, which means Flemoxin will not help. During pregnancy, not only the bladder, but also the kidneys become inflamed (pyelonephritis). In this case, there is a risk of miscarriage.

Before prescribing an antibiotic, it is recommended to take:

  • Antispasmodics (No-shpa, Drotaverine). They make pain easier to bear.
  • Antipyretics (Paracetamol). It is advisable to use only at temperatures above 38 °C.
  • Complex action medications such as Urolesan and Canephron. They relieve inflammation, help against germs and relieve pain.
  • Drink up to 3 liters of liquid during the day (pathogenic microbes are excreted along with urine).
  • Follow a diet. Salt and hot spices cause irritation in the mucous membranes.
  • Apply a heating pad to the lower abdomen.

Flemoxin Solutab and alcohol

Using the drug with alcoholic beverages is unacceptable, as this weakens the body's defense systems. Reduced immunity does not allow a person to normally resist the disease. As a result, the side effects indicated in the annotation appear much more intense. The digestive system becomes upset, attacks of severe nausea and vomiting appear, and sometimes appetite disappears. Added to this is the destructive effect on the liver and kidneys. Malignant tumors in the organs of the genitourinary system are possible.

Contraindications

  • It should not be taken by people who are sensitive to medications based on penicillin and cephalosporin or to any of its components.
  • It is not recommended to take during pregnancy and breastfeeding, except in situations where other methods do not help.

Side effects

Undesirable effects of treatment depend on the duration of taking the drug, the age of the patient and the individual characteristics of his body.

  • Most often the digestive system reacts negatively to this drug. In such cases, an increase or decrease in appetite, diarrhea, nausea and vomiting are observed. These symptoms may indicate an overdose of the drug. Occasionally, acute diarrhea with blood occurs, this is a sign of hemorrhagic colitis.
  • If the patient is prone to allergies, swelling and peeling of the hands and face, nettle fever, and a rash with itching are possible.
  • Tremors of the limbs, dizziness, and possible fainting occur less frequently.
  • In rare cases, cough, narrowing of the bronchi, and Quincke's edema are observed.
  • If the patient has mononucleosis or a malignant lesion of the lymphatic tissue, a skin rash appears in most cases. This phenomenon occurs regardless of the patient's sensitivity to penicillin. In case of such a reaction, there is no need to stop taking the drug.
  • There is also the possibility of superinfection.
  • Resisting the effects of penicillins, microorganisms develop cross-resistance to cephalosporins.
  • When treating cystitis, inflammatory processes in the kidneys of a non-infectious nature are possible.

Interaction with other substances

  • Bactericidal medications like Rifampicin enhance the effect of the drug.
  • The drugs Probenecid, Phenylbutazone and Xifenbutazone reduce the half-life rate of amoxicillin, and accordingly its concentration in the blood increases.
  • Flemoxin sometimes reduces the effectiveness of birth control pills when used simultaneously.
  • If you use drugs with it that suppress the ability of bacteria to reproduce (tetracycline group, macrolides, Chloramphenicol), this may negatively affect its action.

Analogs

Augmentin

In addition to amoxyllicin, the active substance is clavulanic acid, which allows the product to effectively cope with bacteria that produce beta-lactamase. This occurs by slowing down the production of a protective enzyme by microorganisms. Available in the form of tablets, syrup, injection powder, dry substance for the preparation of drops and suspension.

Suprax Solutab

Also a semi-synthetic antibiotic, but with cefixime as the active ingredient. Like Augmentin, it is resistant to beta-lactamases, due to which it affects a wide range of pathogens. However, it is ineffective against most staphylococci, enterobacteria and some other groups of microorganisms. Available in the form of soluble tablets with strawberry flavor. The cost of a package with 7 tablets of Suprax is 900 rubles.

Flemoklav Solutab

The action of this product is based on a combination of amoxicillin and clavulanic acid, which accordingly expands the range of applications. Both components are easily absorbed when consumed orally. This antibiotic should not be taken if treatment requires large doses of amoxicillin. In this case, the intake of clavulanic acid into the body will be excessive. Available in the form of quickly dissolving and easily digestible tablets with a mixed lemon and tangerine flavor.

Source: http://projivot.ru/instruktsiya/flemoksin-solyutab-instruktsiya.html

Antibiotic Flemoxin Solutab for children and adults. Use of the antibiotic Flemoxin Solutab for sore throat

Medicines of the penicillin group occupy an important place in modern pharmaceuticals. Specialists are forced to constantly improve old types of antibiotics, since pathogenic microbes can develop resistance to them over time. Flemoxin is one of these drugs and has a wide spectrum of action.

What does Flemoxin help with?

A common infectious disease is tonsillitis - an inflammatory process in the palatine tonsils. The process, as a rule, also extends to the soft tissues of the palate and the mucous membrane of the larynx. Flemoxin Solutab tablets for angina can be prescribed for the treatment of both adults and children. The antibiotic is indicated for use in the event of any infectious inflammatory processes that were provoked by microorganisms sensitive to the drug. The drug is prescribed for:

  • pharyngitis, otitis, chronic tonsillitis, sinusitis, acute/chronic sinusitis, other diseases of the ENT organs;
  • pneumonia, bronchitis, pleurisy;
  • cholecystitis, cholangitis;
  • cystitis, pyelonephritis, urethritis;
  • skin and subcutaneous inflammations;
  • prostatitis, endometritis, adnexitis, orchitis;
  • meningitis, other brain inflammations;
  • peptic ulcer disease, paratyphoid fever, dysentery, typhoid fever;
  • preparation for surgery to prevent infection;
  • borreliosis, other infectious pathologies;
  • endocarditis.

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Release form and composition of the drug

The antibiotic Flemoxin contains only one active ingredient - Amoxicillin Solutab. This component is a semi-synthetic penicillin, which has a spectrum of action and chemical structure similar to ampicillin. Additional substances of Flemoxin are various substances, including cellulose - they provide solubility to the antibiotic. The tablets have a pleasant citrus taste and the color may be white or pale yellow.

The advantage of Flemoxin over other antibiotics is its bioavailability (93%). This means that the active substance of the drug is used almost in full for therapeutic purposes, without losing its concentration during absorption by the body. The dosage form of Flemoxin is a soluble tablet, which ensures a stable therapeutic effect.

The antibiotic is available in adult and pediatric dosages. The tablets can be swallowed whole, chewed or dissolved in 20 ml of water to make a syrup. Flemoxin suspension (capsule dissolved in 100 ml of water) has a pleasant taste, which is important when prescribing the drug to a child. The capsules can be taken at any time, whether before or after meals, as this does not affect their effectiveness. The drug is also available in the form of injections for injections.

Instructions for use and dosage

The antibiotic Flemoxin is prescribed by a doctor who, based on the patient’s condition, his age and sensitivity to the components of the drug, sets the appropriate dosage. Tablets, as a rule, are not chewed, but swallowed whole with water. In addition, the annotation for the antibiotic states that the drug can be dissolved in water. As a rule, bronchopneumonia in children is treated this way. Before a therapeutic course of taking Flemoxin, you should check for an allergy to the antibiotic using a small dose, and only then can you begin full-fledged treatment.

For adults

Flemoxin tablets are prescribed for the treatment of mild to moderate infectious diseases. The daily dose for an adult is from 0.5 to 2 g, divided into 2 doses. The duration of treatment, as well as the dosage, is determined by the attending physician. As a rule, the course lasts about a week, but in case of streptococcal pathology, the antibiotic is taken for 10 days. Severe infectious diseases or aggravated chronic pathologies are treated by taking 0.75-1 g of the drug three times a day.

For children

The dosage of the antibiotic is prescribed depending on the patient’s age and the severity of the disease. The most acceptable is Flemoxin syrup for children. If there is an inflammatory process of an infectious nature of moderate or mild severity, the doctor prescribes:

  • a child over 10 years old – mg of antibiotic three times a day;
  • child aged 3-10 years – 250 mg three times a day;
  • for a child under 3 years of age - 125 mg three times a day.

Can I take it during pregnancy and breastfeeding?

The description of the drug does not contain any contraindications to taking the antibiotic during pregnancy or lactation. However, the danger of treatment with Flemoxin cannot be excluded, therefore only a doctor can prescribe this drug if the expected effect exceeds the risks of developing side effects in mother and baby. Before use, be sure to do a test to determine an allergic reaction to the antibiotic Flemoxin.

Side effects and contraindications

It is not recommended to combine Flemoxin with bactericidal antibiotics, laxatives, or non-steroidal anti-inflammatory drugs. In addition, doctors do not recommend taking estrogen-containing contraceptives at the same time. It is prohibited to take antibiotics if:

  • severe kidney disease;
  • alcohol intoxication (alcohol will delay the breakdown of the active substance);
  • acute infectious diseases of the gastrointestinal tract, which are accompanied by frequent vomiting, dehydration, diarrhea;
  • ulcerative colitis;
  • allergies/intolerance to the drug;
  • certain types of leukemia, mononucleosis;
  • viral diseases.

It is possible that various side effects may occur while taking the pills. A person may have:

  • loss of appetite;
  • liver dysfunction;
  • vomiting/nausea, colitis, flatulence;
  • Quincke's edema, allergic rash;
  • reduction in the number of platelets, red blood cells, and leukocytes in the blood;
  • the development of a non-infectious inflammatory process in the urinary tract or kidneys.

Reviews about the effectiveness of the drug

Alla, 31 years old: The doctor prescribed Flemoxin when her daughter fell ill with bronchitis. At first I was against taking an antibiotic, but when I found out that the tablets do not cause intestinal dysbiosis, I decided to treat the baby with them. The product was taken, dissolved in water, for 6 days. The terrible cough went away after the first 3 days. No side effects were noticed during treatment with the drug.

Maria, 27 years old: For the treatment of otitis in the hospital, I was prescribed the antibiotic Flemoxin or Sumamed, but another doctor recommended a cheaper substitute for tablets - Amoxiclav. I drank it as much as was indicated in the instructions and I can say that this product is very effective. The pain and other symptoms disappeared before I finished taking the medication. It is not recommended to take pills without permission, but only as prescribed by a doctor.

Karina, 29 years old: This is the second time I’ve given my child Flemoxin. For the first time I was treated with it for a severe sore throat at the age of 3, then I had to take the medicine for 7 days to cope with the disease. Now we are trying to get rid of early pneumonia with the help of an antibiotic so as not to go to the hospital. Four days have passed since the start of treatment, my son’s condition is much better, so I hope that Flemoxin will cope.

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and make recommendations for treatment based on the individual characteristics of a particular patient.

Source: http://sovets.net/5995-antibiotik-flemoksin.html