Complex nasal drops composition dioxidine hydrocortisone

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Complex nasal drops for children: composition, purpose and use

A runny nose accompanies various inflammatory and infectious diseases of the respiratory tract. It is a particularly common problem in childhood.

Table of contents:

Parents are concerned that nasal discharge does not go away for a long time, and nasal drops do not have any effect.

What are complex nasal drops

Complex nasal drops are a solution that is prepared individually for each patient and contains more than two components

Complex nasal instillations are those drops that contain two or more medicinal substances. The doctor writes a prescription necessary to eliminate a runny nose, and pharmacists prepare such drugs. Therefore, you can order and purchase them in pharmacies that have a prescription department. In the prescription, the specialist indicates the dosage, frequency of use and duration of therapy.

You can make complex drops at home, strictly following the preparation instructions given by your doctor, namely the ratio of components and sterility. However, it is better to entrust the preparation of a solution for the treatment of rhinitis in children to an experienced specialist. Under no circumstances should you prepare a product based on a recipe from the Internet or a recipe used by friends. Complex drops not only help reduce discharge and relieve swelling, they act on the causes that provoked the development of the disease: pathogenic bacteria, viral infection, fungus or allergens.

Two-component or multi-component nasal drops are prescribed to children when rhinorrhea does not go away for more than ten days.

Such a remedy is selected with an individual approach. This takes into account the etiology of the disease, which is accompanied by a runny nose, the thickness and color of nasal discharge, the patient’s age, and the characteristics of the body. Also, the choice of components of complex drops depends on the diagnosis and severity of the disease, the child’s weight, and the state of immunity.

Although ready-made combination drops have appeared on the pharmaceutical market, for example, Polydex, Vibrocil, Nasobek, Nasonex, experienced otolaryngologists consider it necessary to prescribe these drugs to both adults and children.

Useful video - Treatment of sinusitis in children with complex drops:

The advantages of complex drops are:

  • Availability and low cost of the components that are part of the combined products.
  • An individual approach to the selection of ingredients for preparing complex drops.
  • The simultaneous use of several components increases the effectiveness of treatment.

Among the disadvantages of such combination drugs:

  • May cause complications.
  • Do not use for ordinary rhinitis.
  • The prepared solution can be stored for no more than fourteen days.
  • If, when preparing it yourself, the proportions of the components are violated, an overdose of the product is possible.
  • There are contraindications to the use of certain substances, as well as adverse reactions.

It is important for parents to remember that it is not allowed to independently select and use complex drops in the treatment of a runny nose in children. After all, such actions can only aggravate the problem and influence the development of undesirable consequences. The remedy is quite powerful, and only a specialist can prescribe it.

Indications for use

Complex drops are prescribed when nasal diseases are protracted and simple drops are no longer effective

Complex drops can be prescribed by a specialist in the following cases:

  • If the runny nose is quite prolonged - up to two weeks.
  • When there is no effectiveness from the use of other nasal drops.
  • If the patient has hypersensitivity to the substances of the combined agents.

Indications for the use of such combined drops are severe forms of the following pathological conditions:

The purpose of complex drops also depends on the etiology of the runny nose (bacterial, fungal, viral, allergic). To determine the cause, the child needs to undergo the necessary tests.

The doctor may prescribe combination drops if you are predisposed to sinusitis (deviated nasal septum, adenoids, polyps, immunodeficiency).

Composition of complex drops

The composition of complex nasal drops for children should be prescribed by a doctor depending on the type, severity of the disease and the age of the child.

Combined preparations for instillation of the nasal passages may include the following components:

  • Antiseptic liquid, saline solution or boiled cooled water are used for the base of nasal drops. Often used for preparation are antiseptics such as Dioxidin or Furacilin, which also have anti-inflammatory and antibacterial effects. Dioxidin helps relieve swelling of the nasal mucosa. Miramistin antiseptic solution can also be used.
  • Protargol or collargol solution. They contain colloidal silver, therefore they are prescribed as a component in the treatment of children from five years of age.
  • Vasoconstrictor components. Facilitate nasal breathing, eliminating congestion and expanding the nasal passages. To prepare complex drops, Metazon, Ephidrine, Adrenaline, Naphthyzin, Nazivin, Galazolin, Farmazolin are used. However, due to adverse reactions, such drugs are used in children in rare cases. This drug is selected depending on the age of the children. It is also important to remember that these drugs are not allowed to be used for more than five days in order to avoid atrophic processes.
  • Antihistamines. They help relieve swelling and relieve burning and itching in the nasal passages. Used for runny nose caused by allergens. Usually, Diphenhydramine and Tavegil, Suprastin are used to prepare combined nasal medications. Among the more modern drugs of the antihistamine group are Zyrtec, Fenistil, Kromhexal.
  • Antibacterial substances. Add to the composition of complex drops if the disease is of bacterial etiology. In this case, the nasal discharge is purulent - with an unpleasant odor and a green tint. The following antibiotics can be used: Penicillin, Lincomycin, Gentamicin, Cefazolin. Complex drops containing such substances should be prepared for children only in pharmaceutical institutions.
  • Excipients of complex drops can be essential oil (pine, eucalyptus, menthol, pine), extracts of medicinal plants (aloe), vitamin preparations in solutions. They have anti-inflammatory and antioxidant properties and help soften the nasal mucosa.
  • Complex drops may include glucocorticosteroids, for example, Hydrocortisone, Dexamethasone, Prednisolone, Bordizone. They are used with caution in the treatment of runny nose in childhood, since they weaken the functioning of the endocrine system with prolonged use.
  • Experts often recommend mixing nasal drops for children, such as Sanorin, Otrivin, Vibrocil, Nazivin.

Recipes for preparing the product

Among the frequently prescribed recipes for children is a remedy that is prepared from the following components:

  • Boiled water (chilled) – 0.3 ml
  • Naphthyzin 0.05% – 7 ml
  • Penicillin – 500 ml bottle
  • Hydrocortisone – 1 ampoule

Drops based on Dioxidin and Naphthyzin are considered effective in the treatment of long-term rhinitis. They are mixed in equal parts for the solution.

Complex drops are also prepared using this recipe:

  • Dioxidin – half an ampoule
  • Dexamethasone – one ampoule
  • Naphthyzin – half a bottle
  • Diphenhydramine – one ampoule

Pharmacies make drops with Hydrocortisone, Dioxidin and Adrenaline. However, such a product is not allowed to be prepared independently.

For bacterial rhinitis, the prescription may include an antibiotic of the cephalosporin group - Cefazolin, which is mixed with Naphthisin, injection solution, Diphenhydramine, aloe juice, Dexamethasone. Another effective recipe for this is a solution containing Hydrocortisone, Dioxidin, Lincomycin, Metazon.

The following remedy can be used for a prolonged runny nose:

Other recipes that specialists can prescribe for rhinitis:

  • Dexamethasone (1ml), Naphthyzin (10 ml), Miramistin (10 ml)
  • Sofradex (5 ml), Dexamethasone (1 ml), Lincomycin (1 bottle), Nazivin (10 ml)
  • Dioxidine (5 ml), Galazolin (5 ml), Dexamethasone (2 ml)
  • Dioxidine (5 ml), Farmazolin (5 ml), Hydrocortisone (2 ml)

There are many recipes for preparing complex drops. But you should not use any without the prescription of a specialist, especially in order to cure a runny nose in a child. The selection of medications for the product is carried out with an individual approach, taking into account all the nuances of the course of the disease and the characteristics of the child’s body.

Features of application

The correct dosage and course of treatment with complex drops is prescribed by the doctor!

It is important to know that complex drops can only be used in the treatment of children if they are prescribed by a specialist.

For the therapy to be effective, it is necessary to adhere to the rules for performing nasal instillation in a child. First, to do this, you should clear the nasal passages of mucus. Rinsing will help clear the nose of secretions. An effective remedy for this is considered to be a medicine based on salt water. In children, nasal cleansing is carried out using a special aspirator.

The dosage of drops is determined by a specialist. Usually it is a few drops alternately into each nasal passage. If it is necessary to use complex drops in small children, you can moisten a cotton swab in the solution for internal use and leave it in the nose for a few minutes. After instillation, it is recommended to soften each nostril with a drop of vegetable oil.

It must be remembered that complex drops can be stored in a cold place for no more than half a month.

Side effects when using drops may include the following reactions: rapid pulse, dry nasal mucosa, decreased local immunity, nosebleeds. These effects mainly appear in case of overdose, which is provoked by violations of the rules for preparing or using complex drops. If such reactions are present, you should consult your doctor about the possibility of further use of the product.

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Recipes and methods of using complex nasal drops for children

For a runny nose that has lasted for several weeks, as well as for sinusitis and sinusitis, the ENT specialist may recommend complex nasal drops for children, the prescription of which should be adjusted according to age.

Please note that making such a remedy at home using recipes found on the Internet is a very dangerous thing. The composition contains far from harmless solutions that can aggravate the child’s condition.

Why are complex drops prescribed for a runny nose?

Some otolaryngologists are of the opinion that drops with a complex composition to combat the runny nose are more effective. Their composition is selected individually to the patient’s condition and complaints. In pharmacies you can find drugs with a combined composition: Vibrocil, Polydexa, Nasonex and Nasobek. Complex drops are undeservedly forgotten, because prescription medications are cheaper, especially since they include components that affect the infection detected in the patient.

Complex nasal drops are prepared exclusively in pharmacies with a prescription department. Finding such a pharmacy in a big city is not difficult, but in small towns it is problematic. Either you will have to go to a neighboring city to get the drops, or you need to make them yourself, maintaining sterility and proportions.

It is hoped that the doctor’s qualifications and experience allow him to correctly select the composition and dosage of medications intended for complex drops. After all, he takes responsibility in case of unsuccessful treatment, deterioration of the patient’s condition or development of complications. Often, such drops help those who have already tried everything, but have not been cured. Sometimes only the second or third composition of prescription drops helps.

When are compound drops prescribed?

  1. For prolonged rhinitis, as well as nasopharyngitis.
  2. In the absence of effectiveness of other single-component and combined remedies for the common cold.
  3. In case of individual intolerance to some components of combined drugs.
  4. In case of severe form of the disease.

Depending on what type of runny nose the patient is suffering from: viral, bacterial or allergic, the doctor selects the composition of the drops. In order to identify the pathogen, you need to undergo tests recommended by your doctor. After receiving the results, the doctor will draw up a prescription for making a remedy for the common cold, and in the prescription he will note the dosage, frequency of instillation and period of use. Reducing the frequency of instillation can delay recovery, but increasing it is dangerous to health.

What products are included in complex nasal drops?

Combined drops for the common cold include drugs from pharmaceutical groups such as:

  1. Vasoconstrictors that relieve swelling from the mucous membrane of the nasal passages. Thanks to them, nasal breathing becomes easier. Pharmacy drops may contain metazone or adrenaline. At home, these drugs can be replaced with naphthyzine, especially when the drug is intended to treat a child. Vasoconstrictor drugs cannot be used for longer than 5-7 days, because atrophy of the nasal mucosa develops.
  2. Antihistamines that relieve allergic factors. This component is relevant for allergic rhinitis. Usually a solution of diphenhydramine or suprastin is used.
  3. Bactericidal components (including antibiotics) designed to disinfect the nasal mucosa and stop the proliferation of pathogenic bacteria. An example is Gentamicin, Lincomycin, Cefazolin and others. These medications are intended to treat runny nose that is only bacterial in nature. A solution of furatsilin may be used as an antiseptic. If the patient has a predisposition to sinusitis or other severe problems associated with difficulty in nasal breathing, Dioxidin, which has anti-inflammatory, antibacterial and decongestant effects, is included in the prescription. However, the use of Dioxidin in children is not permitted according to the instructions for the drug.
  4. Glucocorticosteroids are hormonal drugs that have anti-inflammatory, decongestant and antihistamine effects. The most commonly used are Dexamethasone and Hydrocortisone. Please note that long-term use of these hormonal drugs suppresses adrenal function. For a child over 6 years old, Nazobek can be recommended, and from 2 years old, Nasonex is allowed.

An approximate composition of the drops might look like this:

  1. Galazolin 0.1% 5 ml, dexamethasone 0.1% 2 ml, dioxidine 1% 5 ml.
  2. Mezaton 1% 1 ml, dioxidine 1% 10 ml, aloe juice 1 ml, hydrocortisone 2.5% 2 ml.
  3. Farmazolin 0.05% 5 ml, dioxidine 0.5% 5 ml, hydrocortisone 2.5% 2 ml.
  4. Farmazolin 0.05% 5 ml, diphenhydramine 1% 1 ml, cefazolin 1 bottle, hydrocortisone 2.5% 2 ml, saline up to 10 ml.
  5. Nazivin 10 ml, Sofradex 5 ml, Lincomycin 10% 1 bottle, dexamethasone 0.1% 1 ml.
  6. Nazivin 15 drops, dexamethasone 0.1% 1 ml, dioxidin 5 ml.
  7. Naphthyzin 10 ml, dexamethasone 0.1% 1 ml, Miramistin 10 ml.

For children, as vasoconstrictor drops, you need to take an age-appropriate drug. If the patient has already used Galazolin for a long time without success, the doctor may include Nazivin in the prescription, instead of dioxidine - Miramistin.

Sometimes otolaryngologists add extracts of medicinal plants to complex nasal drops: aloe juice, eucalyptus oil, pine oil, menthol and others. This is acceptable provided that the patient has confirmed that he is not allergic to these components.

Advantages of complex drops for the common cold:

  1. The product is adapted to the specific patient and takes into account the advanced state of the case, the form of the runny nose and sensitivity to medications.
  2. Relatively low cost of the manufactured drug.
  3. Using components to which the patient is not allergic will reduce the likelihood of a negative effect.

Disadvantages of prescription drops in treating a runny nose:

  1. These products have not undergone clinical trials, so the doctor cannot know for sure about all possible side effects and contraindications, as well as the degree of their safety for children and adults.
  2. Labor-intensive manufacturing and inaccessibility in small towns.
  3. When making a home, there is a risk of overdose due to errors and carelessness.
  4. Some components have a systemic effect on the entire body.
  5. The individual components are not intended for administration into the nose.
  6. The possibility of the development of negative processes in the mucous membrane of the nasal sinuses is a change in pH, condition and functioning of cells.

Negative consequences of taking complex drops:

  1. High blood pressure.
  2. Cardiopalmus.
  3. Disturbances in the functioning of the heart.
  4. Drying of the nasal mucosa.
  5. Decreased ability of the nasal mucosa to fight allergens and pathogenic bacteria.
  6. The appearance of nosebleeds.
  7. Transition from acute rhinitis to chronic.
  8. Deterioration of patients' condition due to glaucoma.

It is worth mentioning that the listed symptoms may not be present in your case, but it is better to be warned than to encounter something incomprehensible. If you experience side effects from using compound drops, you should immediately stop taking them and contact your doctor.

Application procedure

  1. Before instilling complex drops, the nose must be cleared of mucus (blow your nose well, rinse with saline solution). For a small child, you can instill Aquamaris drops or saline solution, and then suck out the mucus with a nasal aspirator.
  2. The prescription medicine is instilled 1-2 drops in each nostril in turn. If the child resists, you can drip the product onto a cotton swab and insert it for a couple of minutes, first into one nostril and then into the other.
  3. After allowing breathing, drop a drop of vegetable oil into the right and left nasal passages.

Pay attention to the shelf life of complex drops; it usually does not exceed 1 month.

If the pharmacy bottle does not have a dropper and you use a pipette, you can store the drops for a day.

Complex drops for the treatment of a prolonged runny nose are an effective, but serious drug that requires attention from the attending physician. The patient must carefully observe the dosage and frequency of administration and pay attention to the slightest deterioration in his condition. Treatment of children with complex drops does not always justify the possible risk of complications.

Source: http://respiratoria.ru/raznoe/slozhnye-kapli-v-nos-dlya-detej-recept.html

Complex nasal drops for a child and features of their use

Advantages

Complex nasal drops are selected by the doctor individually for each child, taking into account his age, health condition and complaints. The advantage of manufactured drops is that they:

  • are much cheaper;
  • freshly prepared;
  • are made strictly according to a doctor’s prescription, which means they are optimally selected for your child, taking into account the severity of the disease, the shape and type of the runny nose, and sensitivity to antibiotics.
  • provide the opportunity to select the best combination of components for allergies to certain medications.
  • are a worthy remedy for the treatment of sinusitis.

Not every pharmacy prepares drops, but only the so-called production ones, the number of which is small in the city. You can find such pharmacies at children's hospitals and clinics.

You can buy ready-made complex combination drugs on sale, for example, Polydexa, Vibrocil and Nasonex.

Indications

Complex nasal drops are prescribed:

  • For a runny nose that cannot be treated with other medications within 10 days;
  • For allergies;
  • Nasopharyngitis;
  • For the treatment of sinusitis, including allergic sinusitis;
  • Bordizone is intended for the treatment of adenoids. Bordizone is also prepared in a pharmacy with a doctor's prescription.

What do they include

The complex drops contain only pharmacological preparations; they do not have additives, fragrances or dyes.

The composition of the drops depends on several factors, including the form of the runny nose - allergic, viral or bacterial, and the course of the disease - acute, appearing for the first time, or an exacerbation of a chronic disease.

List of main pharmacological groups of drugs that are included in complex drops prescribed for the treatment of children:

  1. Decogestants or vasoconstrictors: Metazon, Naphthyzin, Xylometazoline (Pharmazolin, Galazolin), Oxymetazoline (Nazivin). They quickly and for several hours relieve swelling of the nasal mucosa, eliminate congestion, and make breathing easier. Treatment with drops containing a vasoconstrictor should not exceed 3–7 days due to the risk of developing atrophy of the nasal mucosa.
  2. Antihistamines: Diphenhydramine or Suprastin is usually used. Intended for the treatment of sinusitis of allergic origin, runny nose due to allergies and bronchial asthma.
  3. Bactericidal agents, including antibiotics. For example, Lincomycin, Gentamicin, Cefazolin, Furacilin, Dioxidin, Miramistin. They are prescribed to disinfect the nose, destroy bacteria, and stop their reproduction. Also to prevent the development of a bacterial infection during a prolonged cold, especially if there is a predisposition to the development of sinusitis - a deviated nasal septum, immunodeficiency, polyps or adenoids.
  4. Hormonal agent. Most often these are glucocorticosteroids - Hydrocortisone or Dexamethasone. Both Hydrocortisone and Dexamethasone have a rapid and persistent anti-inflammatory effect, relieve swelling and allergic reactions. Hormonal drugs should not be used for a long time, not only in children, but also in adults. In childhood, the danger comes from dysfunction of the adrenal glands that produce growth hormone. Therefore, some drugs are approved only for children over 6 years of age. Bordizone contains Hydrocortisone.
  5. Saline solution or injection water. Included in all drops.

A detailed description of contraindications, side effects and the age at which they can be used is contained in the official instructions for use.

Approximate content

approximate composition of complex drops. We do not indicate concentrations and doses, as this should be done by the attending physician. Making and using these drops yourself may pose a risk to your child's health.

  • Recipe No. 1: Farmazolin-Dioxidine-Hydrocortisone.
  • Recipe No. 2: Metazon-Dioxidine-Hydrocortisone.
  • Recipe No. 3: Naphthyzin-Dexamethasone-Miramistin.
  • Recipe No. 4: Galazolin-Dexamethasone-Dioxidine.
  • Recipe No. 5: Nazivin-Dexamethasone-Dioxidine.
  • Recipe No. 6: Farmazolin-Diphenhydramine-Cefazolin-Hydrocortisone.
  • Recipe No. 7: Nazivin-Lincomycin-Dexamethasone.

Sometimes, to treat sinusitis or a runny nose in children, the doctor additionally includes aloe juice, eucalyptus, menthol or pine oil in the composition. This is done provided that the added substances do not cause allergies in the child.

How to use

Before instillation, for better penetration of the medicine into the mucous membrane, the nose should be rinsed well with saline solution and cleared of secretions. To cleanse the nose of crusts 10–15 minutes before the procedure, it can be treated with any vegetable oil. Then place 2-3 drops of medicine into each nostril. If the child refuses instillation, you can soak a cotton swab in the medicine and insert it into the nose for a few minutes.

The frequency and duration of use is determined by the doctor individually in each case.

Flaws

  • Contraindicated for children under 5 years of age.
  • It is difficult to find a commercial pharmacy even in large cities, not to mention small towns and rural areas, where such drops are simply not available to residents.
  • This combination medicine has not undergone clinical trials, so its effect on the body of children and the consequences of its use are unknown.
  • Not all substances included in the composition are intended for instillation into the nose.
  • The more drugs there are, the more contraindications and side effects, and the higher the risk of developing allergies.

If there is no pharmacy that prepares prescription medications, then the drops can be made independently according to the prescription and instructions from the doctor. However, this option is suitable for older children, since the dosage may be inaccurate and the preparation conditions may be far from sterile.

Storage conditions

The prepared product can be used within 7 days. It should be stored in the refrigerator; before use, take the solution into a pipette and warm it in a warm palm.

If, after using complex drops, children develop undesirable symptoms such as jumps in blood pressure, nosebleeds, arrhythmia, discomfort and dry nose, the drops should be discontinued.

Perhaps the doctor chose the wrong dosage, or your child has an intolerance to one of the components included in the composition.

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Complex drops of Dioxidin and Dexamethasone in the nose

There is no such person who would not encounter a runny nose. This unpleasant phenomenon occurs especially in children. Today, pharmacies offer many specialized remedies, but if they do not produce results, the doctor prescribes complex drops with Dioxidine and Dexamethasone for treatment. In our article you will find comprehensive information about the specifics of using complex drops, indications for use and effective recipes.

Drop components

In addition to Dioxidin and Dexamethasone, complex drops may include:

  • Antiseptic liquid, saline solution or boiled cold water. Instead of Dioxidin, which effectively fights swelling of the mucous membrane, Furacilin, a powerful anti-inflammatory and antibacterial drug, can be used;
  • Pharmaceutical vasoconstrictor. It has a beneficial effect on breathing through the nose, fights congestion and expands the nasal passages. Nazivin, Naphthyzin, or Galazolin are considered effective vasoconstrictors, but due to the high likelihood of side effects, treatment with these drugs is used only in extreme cases;
  • Antihistamines (Diphenhydramine, Suprastin and Tavegil). Effectively combat swelling, burning and itching in the nose. Used for a runny nose caused by an allergic reaction;
  • Antibacterial pharmaceuticals (Penicillin, Lincomycin, Cefazolin). They are used to treat diseases with bacterial etiology (the main symptom is purulent green discharge with a specific odor);
  • Glucocorticosteroids (you can replace Dexamethasone with Hydrocortisone, Bordizone or Prednisolone). They should be prescribed for the treatment of children strictly when necessary, since if used incorrectly they negatively affect the endocrine system.

Also, when mixing Dioxidin and Dexamethasone, it is allowed to use essential oils, plant extracts, and vitamins in the form of solutions as additional components. These substances can have an antioxidant effect, fight inflammation and soften the nasal mucosa well.

Recipes for complex drops

Option 1

In the treatment of prolonged rhinitis, it is good to use a solution of Dioxidine, Naphthisin and Dexamethasone. To make it, just mix the above drugs in a 1:1 ratio.

Option 2

A good result is shown by mixing:
  • half an ampoule of Dioxidin;
  • Dexamethasone ampoules;
  • 0.5 bottles of Naphthyzin;
  • Diphenhydramine ampoules.

Option 3

Hydrocortisone + Dioxidine + Adrenaline. But such a mixture must be prepared by a qualified specialist.

Option 4

For the treatment of bacterial rhinitis, it is advisable to use:

  • a mixture of Cefazolin, Naphthyzin, aloe juice and Dexamethasone;
  • solution with Hydrocortisone, Dioxidin, Lincomycin and Metazon.

Option 5

To combat a long-term runny nose, the following is suitable:

  • 2 milliliters Tavegil.
  • 1 milliliter Adrenaline.
  • 8 milliliters of Dexamethasone.
  • 9 milliliters of Albucil.

Option 6

The following mixtures can be used to combat rhinitis:

  • 3 ml of Dexamethasone, 8 ml of Naphthyzin and Miramistin;
  • 5 ml Sofradex, 1.5 ml Dexamethasone, 1 bottle of Lincomycin, 6 ml Nazivin;
  • 5 ml of Galazolin, the proportion of Dexamethasone and Dioxidine is 1:1 (2 ml each);
  • 4 ml of Dioxidin and Farmazolin, 3 ml of Hydrocortisone.

When to take

It is advisable to prescribe complex drops with Dioxidine and Dexamethasone to patients who:

  • Complain about the unsatisfactory effect of using multicomponent drugs or complex therapy;
  • Do not feel any improvement from the prescribed treatment;
  • Suffer from a long course of the disease or its chronic nature;
  • Need complex therapy;
  • They have a mixed nature of the disease (infectious-allergic);
  • Suffer from severe rhinitis, sinusitis or otitis media.

Contraindications

Drops with Dioxidine, Dexamthesone or any other pharmaceutical agent should not be used by patients with hypersensitivity to these drugs. A detailed list of contraindications and side effects is described in the attached instructions.

Side effects

The combination of Dioxidine with Dexamethasone can provoke:

  • drying out of the mucous membrane;
  • severe burning sensation;
  • feeling of hard air when inhaling.

Sometimes patients complained of nosebleeds after using Dexamethasone with Dioxidine. Older patients are more likely to develop glaucoma.

In some patients, in the first days of using complex drops, the following was observed:

  • heart rhythm disturbance;
  • increased heart rate;
  • vertigo;
  • severe weakness;
  • attacks of nausea.

To reduce the likelihood of complications after using Dioxidine and Dexamethasone, the patient should not use them for more than five days. Exceeding this period is permissible only if necessary, solely on the recommendation of a specialist.

Features of application

All complex drops, including those with Dexamethasone and Dioxidine, should be used only as prescribed by a doctor. In order for the procedure to give maximum results, it is necessary to follow the technique of its implementation.

First of all, you need to remove all mucus from the nasal passages. For this it is better to use a saline solution. It is better for babies to clean their nose with a special aspirator.

The dosage of complex drops with Dioxidine and Dexamethasone is established only by a qualified specialist after a thorough examination of the patient. As a rule, the doctor prescribes 3-5 drops into each nasal passage. If the doctor has prescribed Dioxidin with Dexamethasone for the nose of young children, the mother can soak a cotton swab in the medicinal solution and stick it into the nostril for a few minutes. Experts advise adults and children to apply sunflower oil to each nostril after the procedure to soften and minimize the development of discomfort.

Comparison of complex drops and combination preparations

Complex nasal drops have the following undeniable advantages:
  • low cost;
  • the pharmaceutical products used are always available in pharmacies;
  • selection of components taking into account all the individual characteristics of the patient.

The negative aspects of complex drops, for example, the compounds Dioxidine and Dexamethasone, include the lack of professional research on the safety and effectiveness of such medicinal recipes. Because of this, many people, especially parents, prefer to buy expensive combination drugs at pharmacies. It is not uncommon for parents to challenge a doctor’s prescription, according to which the child needs to drip Dexamethasone and Dioxidin into the nose. They believe that the specialist decided to simply conduct an experiment with their child and demand to prescribe a “proven” pharmaceutical remedy.

Having compared the therapeutic effect of complex drops and combined pharmaceuticals, we can only say that their effectiveness largely depends on the patient’s body: what helped one may be useless to another. Therefore, when choosing a treatment method, it is still better to trust the opinion of a specialist.

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Complex nasal drops for children: composition and instructions

Every mother knows firsthand the situation when a child catches a cold and has a runny nose. In ordinary cases, simple nasal drops help, providing quick relief from nasal congestion. However, if the illness has been prolonged and conventional remedies for the common cold do not help, the doctor may prescribe treatment with special compound drops.

Indications for use

Complex drops (compound) are a medicine for the treatment of a runny nose that contains more than one component. Combined drops are able to act in several directions simultaneously, thereby accelerating the healing process.

Complex drops for children are not prescribed very often, since many components are approved for use only from a certain age. But if the cold has become protracted or complications have arisen, the doctor can, at his discretion, create a prescription for compound drops, taking into account the age and physiological characteristics of the child.

Drops are used for the following diseases:

In addition, complex drops can be prescribed by a doctor if a child has an allergic reaction to any particular type of nasal drops.

The composition of nasal drops is determined individually and only by the attending ENT doctor.

The choice of components for complex drops depends on many factors:

  • forms of runny nose (allergic, physiological, bacterial);
  • severity of the disease (acute, chronic);
  • the nature of the discharge from the nasal cavity (thick or liquid, purulent or clear, etc.);
  • characteristics of the body (the presence of contraindications to certain medications);
  • presence of complications (otitis, sinusitis);
  • child's age;
  • presence of an allergy to any medicinal component.

What are complex drops made of? Their composition is varied, as a rule, it is formed by the attending physician depending on the form of the disease. Each ingredient in the compound drops can also act as a separate medicine.

Only a pharmacist in a pharmacy with a special department for preparing prescription drugs can prepare such a solution. You can prepare such a solution yourself if you follow the doctor’s instructions, observe the doses of the components and observe sterility during preparation.

Important! It is not recommended to prepare a solution of drops following recipes posted on Internet resources! The prescription must be written by a competent specialist.

Advantages and disadvantages of using compound drops

Old-time otolaryngologists adhere to the use of compound drops in treatment. However, most modern doctors share the opinion that compound drops are in many ways more effective than modern combined remedies for runny nose and sinusitis, such as Vibrocil, Polidexa, Afrin, Avamis, etc. In order to figure out which is better for the treatment of a runny nose, below is a list of the disadvantages and advantages of combined drops.

Advantages of complex drops

  1. The relative cheapness of the components - the price of such a solution is low, since the dose of each component is minimal and is selected for one therapy and for one person.
  2. Wider spectrum of action - combined drops act on all the unpleasant symptoms of a runny nose, and treatment takes place in a shorter time.
  3. The selection of components occurs individually, taking into account the physiological characteristics of the child.
  4. Ease of use.

Disadvantages of complex drops

  1. Contents of highly active irritants.
  2. Presence of side effects.
  3. Short shelf life.
  4. Inadmissibility of use with a common runny nose.
  5. Presence of contraindications to individual components.
  6. Complex nasal drops for children under 5 years of age are generally prohibited.
  7. Systemic effects of individual components on the child’s body.
  8. Adding non-nasal medications to the composition - adrenaline, hormones.
  9. Presence of allergic reactions to individual components.
  10. Lack of data from clinical studies on the use of drugs in the treatment of sinusitis, sinusitis, and otitis.

It is also worth mentioning the side effects that may arise from the use of such complex drops.

Remember that complex drops can cause a variety of side effects. The instructions usually emphasize this probability. What are these reactions?

  • increased heart rate;
  • increased blood pressure;
  • nosebleeds;
  • transition from an acute form of the disease to a chronic one.

Thus, compound nasal drops in some cases can speed up recovery, in others they not only do not help, but also worsen the state of health. The decision must be made by a specialist and the prescription must be agreed upon with the child’s parents.

Approximate composition of drops

Depending on the nature of the disease, complex drops may contain two or more components. The more components, the more effective the treatment, if all the components of the drops for the child were selected correctly and in the appropriate dosage.

How to make complex drops for children? Antiallergic drugs

Necessary for relieving swelling, as well as unpleasant symptoms - itching, burning, feeling of dryness in the nose. They are especially effective in combating allergic rhinitis.

The main types of antihistamines used in these formulations are Suprastin, Fenistil, Diphenhydramine, Tavegil, Zirtek. It is not recommended to use Zodak, as it contains acetic acid.

Antiseptics and antibiotics

Most often, they are the basis for drops; their main task is to relieve inflammation and swelling, which is important for the bacterial nature of a runny nose or sinusitis. An antibiotic for bacterial rhinitis must be included in the drops!

The main antiseptics that are used to prepare drops: “Dioxidin”, “Furacillin”, “Miramistin”, “Lincomycin”, etc.

You should take into account the fact that the antiseptic “Dioxidin” is a potent substance; according to the instructions, it is prohibited for use by children under 18 years of age! When applied topically, the drug should be used with caution, since long-term use and overdose can cause atrophy of the nasal mucous membranes.

Vasoconstrictor drops (decogestants)

This component must necessarily contain complex drops; the composition of the drops cannot be complete without this kind of preparation, since their task is to relieve swelling in the nasal cavity and provide air access to the nasal passages.

When choosing vasoconstrictor drops, you should take into account the fact that their use in children can cause increased blood pressure and increased heart rate, so you should choose the most gentle drugs.

If the solution is prepared in a pharmacy, then drops such as Metazon can be added to the composition. If you are preparing complex nasal drops for children at home, the composition can be supplemented with any ready-made vasoconstrictor drops: “Nazivin”, “Naphthyzin”, “Oxylometazoline”.

When choosing vasoconstrictors, the doctor needs to find out what nasal drops the parents used before visiting the doctor; if the child is not accustomed to them, the doctor can also include them in the drops prescription. If dependence on nasal drops has appeared, then perhaps the doctor will select others, taking into account the age of the child.

Hormonal substances

The addition of hormonal drugs is required if the form of the disease is severe and conventional vasoconstrictors do not help. They provide relief from swelling and inflammation, as well as allergic reactions.

Usually, hydrocortisone is added to the solution - a hormone that can relieve all symptoms of a runny nose in a very short time. You should be aware that long-term use of such a drug can cause dysfunction of the adrenal glands, which are responsible for the growth of the body, so this drug should be prescribed to children with caution.

If the child is under 6 years old, then you can purchase the intranasal drug “Nasonex” or “Nasobek” for him. These are ready-made drops for the treatment of persistent runny nose, and they can be used from a young age.

Immunomodulatory substances

Added to support the child’s immunity during illness. At the same time, they are not such a necessary component in the preparation of the composition. The simplest immunomodulator is the well-known Interferon, which perfectly complements complex drops for children. The instructions for the drug do not prohibit this.

Saline solution

Included in all formulations of such drops, it is the basis.

Additional components

These include various essential oils or extracts of medicinal plants. Added at the discretion of the doctor.

Their use in compound drops is necessary to eliminate dryness of the nasal cavity, relieve inflammation, and also restore damaged nasal mucous membranes.

Important! It is not recommended to use vasoconstrictor drops for more than 5-7 days. Long-term use of such drops causes atrophy of the nasal mucosa.

Sample recipe options

Below are only approximate recipes for compound drops, but a more precise dosage and list of components should be determined by the attending ENT doctor.

The most famous recipe in otolaryngology. How to prepare classic complex drops? The proportions are one to one, the drugs “Miramistin” and “Naphthyzin” (0.05%) are taken and these equal parts are mixed together.

You can use an empty Naphthyzin container as a container. It is acceptable to use Miramistin alone, but if the swelling is severe, then it is better to combine these two drugs. This recipe is used mainly for children who have been diagnosed with adenoids.

Here are more complex drops for children. The composition is as follows: Miramistin, Diphenhydramine, Naphthyzin (or Naphazolin), Hydrocortisone (or Dexamethasone). This composition of drops is prescribed by a doctor for sinusitis (especially chronic), bacterial rhinitis, and complications of rhinitis (otitis).

This recipe is prepared only in a pharmacy by a pharmacist - suspension "Hydrocortisone", "Albucid". The results are very effective, complex drops, the recipe of which is not a secret, but their use requires very specific medical indications.

"Albucid" is a powerful antibacterial agent with a broad spectrum of action. It can be combined with Nazivin, or simply with the hormone Hydrocortisone. "Albucid" can also be used for newborns as a prophylaxis for blenorrhea. But it should be used with caution, as this drug causes a burning sensation in the nose.

How to choose combination drops?

To do this, you need to visit a specialist (otolaryngologist), he will conduct the necessary examination, prescribe tests and, after studying the medical history, if the diagnosis is confirmed, he will draw up a prescription for combined drops.

Next, you need to purchase all the necessary components at the pharmacy or find a prescription department where you can order the composition of the drops prescribed by your doctor.

After this, you need to submit a request for the pharmacist to prepare complex drops for you. The production of compound drops does not take much time, they can be collected immediately on the spot. After this, you can begin treatment measures.

Specialized prescription departments of pharmacies, unfortunately, are found only in cities and in small quantities, so the majority of the population resorts to making compound drops on their own.

Instructions for using a solution of a few drops

Before use, the solution must be warmed to room temperature.

Drops can be used for 5-7 days (no longer), no more than 2 drops should be instilled and no more than 3 times a day.

Before using compound drops you must:

  1. Clear your child's nose. To do this, the child needs to blow his nose on his own if he is old enough to do this, or clear his nose with an aspirator or bulb if the child is very small or a newborn. Saline solution or spray “Aquamaris”, “Aquamore”, “Aqualor” can be used as a means for rinsing the nasal cavity and paranasal sinuses. These solutions include sea salt, which allows you to effectively clean and disinfect the nasal cavity and paranasal sinuses.
  2. Place compound drops into the nose. The composition of the drops, as already mentioned, will be determined by the doctor. The compound medicine is instilled one or two drops into each nostril. If the child is an infant, then you can use a cotton swab. To do this, you need to roll it into a tight flagellum, lightly dip it in the medicine and stick it into the child’s nostril and hold it for a while. After this, remove the tampon. Do the same with the other nostril; the cotton swab for each nostril should be separate.
  3. Apply oil to your nose. After nasal breathing has become free and easy, you need to drop one drop of vegetable oil into each nostril. This procedure is necessary to avoid drying out the nasal mucosa during treatment with combined drops.

Storage conditions

It is recommended to store complex drops in the refrigerator, since at room temperature the active ingredients may lose their properties (especially hormones).

If the drops are in a glass vial and a pipette is used for instillation, then the drops can be stored for no more than 7 days. If the solution is in a closed bottle with a hole, the shelf life can be up to two weeks. After the expiration date, the drops cannot be used and must be disposed of immediately.

Thus, despite the advantages of using such drops for prolonged forms of runny nose and complications of colds, the doctor, as well as the child’s parents, must weigh the benefits and harms of using such drops for him.

Source: http://www.syl.ru/article/291334/slojnyie-kapli-v-nos-dlya-detey-sostav-i-instruktsiya

Complex nasal drops for rhinitis and sinusitis

Everyone at least once in their life has had to go to a prescription pharmacy, where they received a special medicine. In this review we will talk about complex drops, which are also prepared by pharmacists according to an ENT doctor’s prescription.

There may be several indications for therapy with complex drops, but most often they are resorted to if treatment with traditional drugs does not bring the desired result. A prolonged runny nose causes a lot of inconvenience, reduces the quality of life and can cause the development of other inflammatory diseases of the ENT organs.

Indications

An otolaryngologist may prescribe combination drops in the following cases:

  1. In case of chronic rhinitis and the appearance of complications against its background;
  2. The likelihood of otitis media;
  3. Rhinosinusopathy;
  4. In the presence of prolonged inflammation in the nasopharynx;
  5. If you have an allergic reaction to certain nasal medications or there is no result from taking single medications.

Under sterile conditions, pharmacies prepare drops for the eyes, ears and nose. Some formulations are universal and can be used in the treatment of all ENT organs.

It should be noted that modern doctors do not so often resort to the services of complex drops, but are more inclined to prescribe treatment with modern drugs. Recent medical graduates are more likely to write a prescription for Polydexa than to select the composition of complex drops. Just choose, since the composition will change along with the patient’s clinical picture.

If the cause of rhinitis and subsequent inflammation is a viral infection, then the drops will contain an anti-inflammatory, vasoconstrictor and antiviral group of medications.

If the allergic component of the runny nose is not excluded, then an antihistamine, hormonal and immunomodulatory group is added to the combined drops.

Often the drops are based on vasoconstrictor monodrops such as Naphthyzin (for children, if the composition is prepared for a child).

The anti-inflammatory group is almost always present in the drug, but the hormonal group is resorted to when other drugs are powerless.

Fund groups

  1. Vasoconstrictors;
  2. Hormonal;
  3. Antihistamines;
  4. Vegetable;
  5. Homeopathic;
  6. Immunomodelling;
  7. Antibacterial;
  8. Antiviral.

Advantages and disadvantages

Complex drops have supporters and opponents. What speaks in favor of combined formulations is that they:

  1. Publicly available - can be purchased at any pharmacy;
  2. Effective and safe due to individual selection of drugs;
  3. They are distinguished by their low price;
  4. There is the possibility of cooking at home.

The disadvantages of complex drops include what was recently regarded as an advantage - the ability to prepare at home. Here you need to approach it with all seriousness and strictly follow the recipe for the preparation of the composition and the selection of drugs. You should also be conscientious and ensure maximum sterility when preparing the composition at home. Short shelf life of the product. There is some likelihood of increased blood pressure or its systemic effect on the entire body. Prohibited for use in children under 5 years of age.

Although there are cases when doctors take responsibility and, carefully calculating the dosage, prescribe such drops to young children.

Recipe

  1. The first and simplest recipe includes only three components: Adrenaline, Hydrocortisone and Dioxidin (all drugs are taken in 1 ampoule). This composition is aimed at getting rid of severe rhinitis, where Hydrocortisone will relieve inflammation and swelling, and Dioxidin will play the role of an antiseptic.
  2. When fighting adenoids in children, doctors issue prescriptions for the preparation of a composition of Dioxidin and Naphthyzin (0.05%), which must be mixed in a 50/50 ratio.
  3. Composition for children: Dexamethasone (1 ampoule) and 0.5 bottles of Naphthyzin (0.05%).
  4. When it is necessary to fight bacteria, the antibiotic Penicillin (bottle) should be included in the drops, 0.3 ml of saline solution, to which one ampoule of Hydrocortisone and 1 ml of Naphthyzin are added.
  5. The composition of the drops for sinusitis must necessarily include an antibiotic drug (Lincomycin, Gentamicin or Penicillin itself).
  6. The sixth multicomponent version of the composition includes Lincomycin 30%, one ampoule of Mezaton 1%, Dioxidin 5 ml, Hydrocortisone 1 ampoule.

Furacilin, Collargol, Protargol, which play the role of antiseptics, can be used as the main component of the drug. Furacilin solution is very often used by otolaryngologists. Another popular drug is Protargol, which is made from silver.

If it is necessary to exclude the possibility of a negative effect of the allergen, then Diphenhydramine or Suprastin is added to the composition of the complex drops. These drugs will reduce swelling and itching of the mucous membrane. To reduce the diameter of blood vessels, complex drops are supplemented with Farmazolin, Mezaton, Adrenaline or Naphazolin.

Polycompositions may include hormonal drugs, especially if an adult is being treated. Most often this is Hydrocortisone. Pediatric otolaryngology does not exclude the use of hormonal drugs such as Nasonex, Beconase or Nasobek.

In addition, vitamins E, A, aloe juice, essential oils and extracts of medicinal herbs are additionally added to the recipes.

It is important to remember that, no matter how similar the symptoms are in two patients, and the material you read on the Internet does not inspire confidence, you should not self-medicate or compose a drug formulation. This is the prerogative of an experienced doctor - a pediatrician or ENT specialist. Only a qualified specialist can accurately calculate the proportions and create the necessary prescription for effective treatment. Instructions for complex nasal drops for children will also be announced by a physician.

Reviews

If you read the reviews, you can conclude that this type of drops is effective.

After each ARVI, my daughter’s runny nose lingered for another 3 weeks. A furatsilin-adrenaline solution was used to rinse the nose, after which Pinosol was instilled.

Instead of Hydrocortisone, I was prescribed Bordizone. Mixing was done independently at home. The main thing is to follow the dosage exactly and store the product in the refrigerator.

My son was diagnosed with a second degree adenoid. Treatment was prescribed: 1 ampoule of Dioxidin + 1 ampoule of Dexamethasone + Naphthyzin for children (15 caps). Rinse your nose with Aquamaris or Merimer. Now we are going through the course, we hope to win over adenoids.

Source: http://nasmorku.net/lekarstva/slozhnye-kapli-v-nos-pri-rinite-i-gajmorite