Is it possible to take Suprastin

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Suprastin - instructions for use: price, analogues and dosage for children, adults and during pregnancy

Suprastin is a prominent representative of the first generation of antihistamines, the mechanism of use of which is aimed at blocking histamine receptors and providing an antispasmodic effect.

Table of contents:

Numerous studies that have been conducted on chloropyramine have shown that Suprastin is very effective in the treatment of hay fever and other allergic pathologies.

Despite the emergence of the latest generation of drugs with a limited list of side effects, Suprastin is still used when an immediate effect is needed. 15 minutes pass and the first signs of the action of the antiallergic drug are already noticeable. However, do not forget that self-medication can lead to undesirable results. Suprastin can be self-prescribed once before the doctor arrives, only in an emergency. Or if you are sure that the child is really having an allergy attack and has already had such signs before and the drug has already been prescribed.

How does suprastin work?

In the treatment of allergic reactions, drugs that affect histamine metabolism (antihistamines) are used. The action of suprastin in allergies is primarily aimed at suppressing the activity of histamine. Suprastin blocks histamine receptors (H1), thus preventing the appearance of signs and symptoms of allergies. In addition, suprastin has a pronounced antipruritic effect.

After taking Suprastin orally, the drug is quickly and completely absorbed into the blood from the intestines. The maximum concentration of the drug is reached 2 hours after application. As a rule, suprastin distributes well in the human body (penetrates the brain). The drug is excreted through the kidneys (in case of renal failure, the dose of the drug should be reduced).

Pharmacodynamics

Chloropyramine, a chlorinated analogue of tripelenamine (pyribenzamine), is a classic antihistamine that belongs to the group of ethylenediamine antihistamines. A blocker of H1-histamine receptors, has an antihistamine and m-anticholinergic effect, has an antiemetic effect, moderate antispasmodic and peripheral anticholinergic activity.

Pharmacokinetics

When taken orally, it is almost completely absorbed from the gastrointestinal tract (GIT). The therapeutic effect of chloropyramine develops within 15–30 minutes after oral administration, reaches a maximum within the first hour after administration and lasts at least 3–6 hours. Well distributed throughout the body, including the central nervous system (CNS). Intensively metabolized in the liver. It is excreted mainly by the kidneys. In children, drug elimination occurs faster than in adult patients.

Indications for suprastin

  • hives;
  • angioedema (Quincke's edema);
  • serum sickness;
  • seasonal and year-round allergic rhinitis;
  • conjunctivitis;
  • contact dermatitis;
  • skin itching;
  • acute and chronic eczema;
  • atopic dermatitis;
  • food and drug allergies;
  • allergic reactions to insect bites.

Contraindications

  • hypersensitivity to the components of the drug;
  • acute attack of bronchial asthma;
  • newborn babies (full-term and premature);
  • pregnancy;
  • lactation period.
  • angle-closure glaucoma;
  • urinary retention;
  • prostatic hyperplasia;
  • liver and/or kidney dysfunction;
  • cardiovascular diseases;
  • elderly patients.

Method of application and dosage of suprastin

The tablets are taken orally during meals, without chewing and with a sufficient amount of water.

For adults

Prescribe 1 tablet 3-4 times a day (75-100 mg per day).

For children

  • at the age of 1 to 12 months - 1/4 tablet (6.5 mg) 2-3 times a day (ground to powder along with baby food);
  • At the age of 1 to 6 years - 1/4 tablet 3 times a day or 1/2 tablet 2 times a day;
  • At the age of 6 to 14 years - 1/2 tablet (12.5 mg) 2-3 times a day.

The dose can be gradually increased if the patient has no side effects, but the maximum dose should never exceed 2 mg/kg body weight.

Special patient groups

Elderly, debilitated patients: the use of the drug Suprastin requires special caution, because in these patients, antihistamines are more likely to cause side effects (dizziness, drowsiness).

Patients with impaired liver function: a dose reduction may be required due to a decrease in the metabolism of the active component of the drug in liver diseases.

Patients with impaired renal function: a change in the dosage regimen and a dose reduction may be required due to the fact that the active component is mainly excreted through the kidneys.

How long can you take Suprastin

The course of treatment with Suprastin is prescribed by a doctor and is selected individually for each patient depending on the course of the disease and its complexity.

Use of suprastin during pregnancy

There have been no adequate and well-controlled studies of the use of antihistamines during pregnancy. Therefore, the use of the drug in pregnant women (especially in the first trimester and the last month of pregnancy) is possible only if the potential benefit to the mother outweighs the possible risk to the fetus.

If it is necessary to use the drug during lactation, breastfeeding should be suspended.

The use of suprastin in childhood

It can be used according to indications and in doses taking into account the patient’s age. The drug is not prescribed to newborns (including premature infants). The medicine is recommended for children starting from 1 month of life. The course and frequency of use directly depend on the pathological process. In case of mild manifestations of an allergic reaction, the drug can be given to the child no more than 1 time per day. And if the allergy occurs in a complex form, then you can take the drug 3 times a day.

Parents should remember that a child may have a completely atypical reaction to the drug Suprastin in the form of hyperexcitability, anxiety and insomnia. The course of treatment for children with Suprastin cannot last more than 7 days; if during this period of time the signs of allergy have not disappeared, then you need to seek help from a doctor.

Side effects

Side effects, as a rule, occur extremely rarely, are temporary, and disappear after discontinuation of the drug.

  • From the central nervous system: drowsiness, fatigue, dizziness, nervous excitement, tremor, headache, euphoria.
  • From the gastrointestinal tract: abdominal discomfort, dry mouth, nausea, vomiting, diarrhea, constipation, lack or increased appetite, pain in the upper abdomen.
  • From the cardiovascular system: decreased blood pressure, tachycardia, arrhythmia. A direct connection between these side effects and the use of the drug has not always been established.
  • From the hematopoietic system: very rarely: leukopenia, agranulocytosis.

Other: difficulty urinating, muscle weakness, increased intraocular pressure, photosensitivity.

Overdose

Symptoms

  • hallucinations;
  • anxiety;
  • ataxia;
  • impaired coordination of movements;
  • athetosis;
  • convulsions.

In young children, agitation, anxiety, dry mouth, fixed dilated pupils, facial flushing, sinus tachycardia, urinary retention, fever, coma.

In adults, fever and facial redness are observed intermittently, after a period of excitement followed by convulsions and post-convulsant depression, coma.

Treatment

In the period up to 12 hours after taking the drug orally, gastric lavage is necessary (it should be taken into account that gastric emptying is prevented by the anticholinergic effect of the drug). The use of activated carbon is also indicated. Monitoring of blood pressure and breathing parameters is necessary. Symptomatic therapy. Resuscitation measures. A specific antidote is not known.

Interaction with other drugs

The drug should be used with caution with sedatives, tranquilizers, analgesics, MAO inhibitors, tricyclic antidepressants, atropine and/or sympatholytics, since the effects of these drugs may be enhanced when used simultaneously.

Interaction of suprastin with alcohol

Suprastin tends to enhance the effect of ethyl alcohol on the central nervous system. During the course of therapy, you should abstain from any alcohol (including medicinal tinctures).

Special instructions for use

Each tablet contains 116 mg of lactose monohydrate. This amount may cause undesirable reactions in patients with lactose deficiency or rare metabolic disorders - galactosemia or glucose/galactose malabsorption syndrome.

When combined with ototoxic drugs, Suprastin can mask early signs of ototoxicity.

Diseases of the liver and kidneys may require a change (reduction) in the dose of the drug, and therefore the patient should inform the doctor about the presence of

Transport and machinery management

The drug, especially in the initial period of treatment, may cause drowsiness, fatigue and dizziness. Therefore, in the initial period, the duration of which is determined individually, driving vehicles or performing work associated with an increased risk of accidents is prohibited. After this, the degree of restriction on driving vehicles and operating machinery must be determined by the doctor individually for each patient.

Release form

Tablets 25 mg. 20 tablets in brown glass bottles with PE caps. The bottle is packaged in a cardboard box along with instructions for medical use. Or 10 tablets per blister. 2 blisters are packed in a cardboard box along with instructions for medical use.

In addition to the standard pack, in pharmacies there is a variety in the form of ampoules containing 20 mg of chloropyramine hydrochloride. It is sold in packs of 5 ampoules and contains, in addition to the active substance, water for injection.

A solution for intravenous and intramuscular administration is used when there is an urgent need to relieve allergy symptoms - Quincke's edema, suffocation or convulsions. In such cases, the solution is administered intravenously for immediate action. To use at home, you must have skills in intravenous injections for children.

Storage conditions

At a temperature of 15–25 °C, out of the reach of children.

Best before date

5 years. Do not use after the date indicated on the package.

Conditions for dispensing from pharmacies

Price for suprastin

  • tablets 20 pcs. in packaging - from 110 rubles;
  • solution of 10 ampoules per package – from 150 rubles.

Suprastin analogues

Today, there are a large number of antihistamines that help effectively combat the body’s allergic reactions to any of the existing allergens, the most common:

Suprastin or tavegil

What is better to take during allergies - Suprastin or Tavegil? These medications belong to one group of drugs – antihistamines. The main indication for both Suprastin and Tavegil are allergic diseases of various natures.

But what is better – Tavegil or Suprastin? The main difference between these drugs is the manufacturer: Suprastin is a domestic medicine, Tavegil is a foreign one. Unlike Suprastin, Tavegil is prescribed to children over six years of age.

The effectiveness of both drugs is quite high. Both drugs belong to the first generation of antiallergic drugs. The basis of Tavegil is the substance clemastine, and Suprastin is chloropyramine.

Suprastin has a significant side effect: severe drowsiness. Tavegil is devoid of this side effect, which distinguishes it favorably from Suprastin. However, Tavegil has a much wider range of contraindications and side effects.

Suprastin or Cetrin

Cetrin (cetirizine hydrochloride) is a 2nd generation drug that is a highly selective antagonist of H1-type histamine receptors. The drug has 2 release forms - tablets, which are used in patients over 6 years of age, and syrup, which is prescribed from 2 years of age.

Cetirizine hydrochloride is practically not biotransformed in the body; the rate of its elimination is related to the functional state of the kidneys. A special feature of the drug is its ability to penetrate well into the skin, which makes Cetrin especially effective for skin manifestations of allergies.

The drug does not have a proarrhythmic effect, which has been proven in preclinical and clinical studies. This means that the use of Cetrin is much less likely to be accompanied by the development of adverse reactions than the use of 1st generation products. Moreover, the degree of expression of the latter is also less than that of Suprastin.

If we talk about antiallergic activity, then Suprastin is considered a somewhat stronger remedy.

Questions and answers on the topic "Suprastin"

Question: Hello. Today we were given vaccinations (hepatitis B, polio, diphtheria, whooping cough and tetanus), they told us to drink Suprastin 1/4 at home before meals, but they didn’t tell us how many times a day to give or for how long to take it. My son is 4 months old. Do I need to give suprastin and how many times?

Source: http://www.diagnos-online.ru/lekarstvennye-preparaty/suprastin.html

How and how much to take Suprastin for allergies?

How to take Suprastin for allergies? This drug is considered an effective fighter against pathological conditions caused by exposure to allergens of various natures. The medicine is a powerful antihistamine prescribed for angioedema, urticaria, allergic dermatitis, conjunctivitis, rhinitis, hay fever and other hyperreactive conditions.

Content

How does Suprastin work for allergies?

Suprastin is an antihistamine. The main pharmacological action is to block the receptors of histamine-sensitive cells. Histamine is a highly active biological compound released when cells are damaged by allergens. When its concentration is strong, the main symptoms of allergies are noted:

  • skin rashes,
  • allergic cough,
  • itching and burning of the skin,
  • runny nose and conjunctivitis of an allergic nature,
  • hypotension, a feeling of loss of strength and unmotivated weakness.
  • spasm of smooth muscle fibers,
  • edema.

Suprastin reduces the severity of negative manifestations of allergies, relieves inflammation and reduces itching, and has a mild hypnotic effect (not as pronounced as other first-generation antihistamines).

Benefits of Suprastin

Suprastin belongs to the first generation of antiallergic drugs. And although there are stronger antihistamines, Suprastin is still the most popular allergy drug. Let's consider its advantages:

  • The antiallergic effect is achieved very quickly - the condition noticeably improves within half an hour after taking the medicine.
  • Taking Suprastin does not have such pronounced negative consequences as the use of other first-generation drugs (for example, Diphenhydramine).
  • Compared to more modern means, Suprastin is much more affordable, although it is not much inferior to them in effectiveness.
  • The medicine has a small range of contraindications.
  • The drug is available both in tablet form and in ampoules. Therefore, in acute conditions that require immediate intervention (swelling of the larynx, anaphylactic shock), Suprastin injections become an important way to help the patient.

to contents ↑

How to take Suprastin?

Suprastin is prescribed for respiratory and food allergies, if a reaction occurs after contact with an allergen or taking medications. The drug can be taken both for prophylactic purposes and to treat the symptoms of an allergic reaction. The peculiarity of this medicine is its short-term effect; it should be used at least three times a day to obtain a positive effect.

The dosage and frequency of administration are selected individually by the attending physician. For prevention, one tablet per day is enough. For severe symptoms, up to 4 tablets of Suprastin per day are prescribed. The medicine must be taken after meals.

When taking it, you should take into account that the side effects of Suprastin are drowsiness, lethargy and fatigue. They can manifest themselves differently in patients, varying widely. After taking the medicine, concentration and reaction speed decrease. Accordingly, the drug is prohibited from being taken by persons whose work requires extreme concentration or involves driving a vehicle.

Suprastin is contraindicated during pregnancy and breastfeeding. Concomitant use with alcoholic beverages or ethanol-based drugs can cause severe side effects.

How much can you drink Suprastin?

How much to take Suprastin for allergies? The duration of therapy is determined individually - it depends on the severity of pathological symptoms and the body's sensitivity to the drug itself. Typically, treatment is carried out in courses of 5-7 days when the allergic process worsens. In severe cases of the disease, this period may be extended. However, long-term treatment can lead to addiction, and the drug will not be as effective as when you started taking it.

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Full or partial reproduction of site materials is possible only if there is an active indexed link to the source. All materials presented on the site are for informational purposes only. Do not self-medicate; recommendations should be given by your attending physician during a face-to-face consultation!!

Source: http://allergolife.ru/kak-i-skolko-prinimat-suprastin-pri-allergii/

Suprastin

Description current as of 08/11/2015

  • Latin name: Suprastin
  • ATX code: R06AC03
  • Active ingredient: Chloropyramine
  • Manufacturer: EGIS Pharmaceuticals PLC (Hungary)

Compound

Suprastin tablets contain 25 mg of chloropyramine hydrochloride, gelatin, lactose monohydrate, stearic acid, sodium starch glycolate type A, potato starch, talc.

Suprastin in ampoules contains chloropyramine hydrochloride and water as an auxiliary component.

Release form

The medicine has 2 forms: tablets 25 mg and solution d/i 20 mg/ml.

Suprastin tablets are disc-shaped, grayish-white or white. The name “SUPRASTIN” is engraved on one side and a line on the other. The smell is weak or completely absent. The tablets are packaged in blisters of 10 pieces, 2 blisters in a package.

The aqueous solution is transparent and colorless, with a slight specific odor. Available in ampoules with a capacity of 1 ml, package No. 5.

pharmachologic effect

Pharmacodynamics and pharmacokinetics

The active substance of Suprastin is a chlorinated analogue of tripelenamine and belongs to the group of 1st generation antihistamines, which - due to the main side effect - are also called sedatives.

The mechanism of action of chloropyramine is due to the ability of this substance to block histamine type H1 receptors. Studies (both preclinical and clinical) prove its effectiveness against hay fever and other allergic diseases.

Like other H1 blockers, the drug's action is aimed primarily at preventing immediate hypersensitivity reactions, and in cases where the reaction has already begun to develop, at preventing further histamine release.

Experiments on guinea pigs showed that even in a very low dosage, the drug protected animals from the effects of histamine at a dose 120 times higher than the lethal dose.

Chlorpyramin also affects the central nervous system, capillary permeability and smooth muscle.

Absorption from the digestive canal after taking the required dose is rapid. The effect is observed within minutes after taking the tablet, reaches its maximum within 1 hour and lasts for up to 6 hours.

Chlorpyramin is metabolized in the liver. Metabolic products are excreted mainly by the kidneys. Moreover, the drug is eliminated from the body of a child faster than from the body of an adult.

In patients with renal dysfunction, the elimination of chloropyramine may be reduced. With liver dysfunction, the metabolism of the substance slows down, which requires changing the dose of the drug.

Indications for use: what are Suprastin tablets and solution used for?

Suprastin tablets - what are they for?

Suprastin tablets are used in allergology:

The drug can also be prescribed to reduce swelling of the mucous membrane of the middle ear and nose during infections of the ENT organs (sinusitis, otitis media).

What does Suprastin in solution form help with?

Indications for the use of Suprastin in the form of a d/i solution are the same as for the tablet form of the drug.

Contraindications

Contraindications for Suprastin:

Side effects

Side effects of Suprastin from the central nervous system: increased fatigue, sedation, ataxia, dizziness, convulsions, tremor, headache, encephalopathy, decreased visual clarity, euphoria, drowsiness, impaired psychomotor functions.

From the cardiovascular system, arrhythmia, tachycardia, and arterial hypotension are possible. From the digestive system: discomfort and pain in the epigastrium, dry mouth, diarrhea, nausea, vomiting, increased symptoms of gastroesophageal reflux, increased or complete lack of appetite.

On the part of the blood system, in rare cases, pathological changes in the blood may be observed (for example, agranulocytosis, hemolytic anemia, leukopenia, thrombocytopenia, etc.).

From the urinary system and kidneys: urinary retention, dysuria.

From the subcutaneous tissue and skin: hypersensitivity reactions, as well as a painful reaction to sunlight.

From the musculoskeletal system: myopathy.

Reactions of the immune system to the use of the drug can be expressed in the form of skin itching, the appearance of a rash, skin hyperemia, urticaria, and angioedema.

Other side effects: changes at the injection site of the d/i ​​solution.

Instructions for use of Suprastin

Suprastin tablets: instructions for use. How to take Suprastin for adults?

The tablets should be taken with food, without crushing or chewing, and with liquid.

For adults, Suprastin tablets are prescribed to be taken daily. Exceed the dose of 100 mg/day. contraindicated.

Treatment is considered complete when all clinical symptoms are eliminated. If the above adverse reactions develop, the medication should be stopped.

How to take Suprastin if you have allergies if the disease is severe?

In acute severe conditions or anaphylactic shock, treatment begins with intravenous administration of the drug (intravenous injection should be performed very slowly). Subsequently, they switch to injecting the solution into the muscle or taking tablets.

The duration of use for severe allergies is determined by the attending physician.

Instructions for use of Suprastin in ampoules

Suprastin injections can only be given by a nurse or doctor.

The dosage of Suprastin for an adult is usually 1-2 ml/day. The drug is injected into the muscle. In especially severe cases, treatment begins with intravenous injections.

In case of liver dysfunction due to a decrease in the metabolism of the active substance, the patient may require a dose adjustment towards its reduction. A dose reduction is also necessary for patients with renal dysfunction, which is associated with the participation of this organ in removing chloropyramine from the body.

How many days should adults take Suprastin?

The duration of treatment depends on the severity of allergy symptoms and the body's sensitivity to chloropyramine. As a rule, the medicine is taken in short courses (5-7 days) when the process worsens. In case of severe disease, the doctor may make other prescriptions.

It should be remembered that with prolonged use of the drug, the patient may develop addiction to it.

Instructions for use of Suprastin for children

The use of Suprastin is also advisable for chickenpox: the drug can reduce the intensity of itching and somewhat calm the child’s nervous system.

Before giving Suprastin to children, you should read the list of contraindications. The use of tablets is contraindicated in children under 3 years of age; the solution is not prescribed to newborn infants (including premature infants).

In addition, you should not give the medicine in any form during an acute attack of asthma, intolerance to chloropyramine or any of the auxiliary components.

The manufacturer does not produce special children's Suprastin with a lower dosage of the active substance. There are no other dosage forms (ointment, drops, syrup) except tablets and solution.

How should children take Suprastin tablets?

Dosage of Suprastin for children under 6 years of age: 1 tablet/day, divided into 2 doses. According to the instructions, for children 6-14 years old the dose is 1-1.5 tablets/day. (0.5 tablets at each dose).

Depending on the body's response to treatment, the dose can be increased if necessary. The highest dose for a child is 2 mg/kg/day.

For infants, Suprastin tablets are prescribed, if necessary, 1/4-1/5 tablet. 2 rubles/day..

The solution, like the tablets, is dosed depending on the patient’s age: children under one year of age are administered 0.25 ml at the initial stages of treatment, children aged 12 months to 6 years - 0.5 ml, children aged 6- 14 years - from 0.5 to 1 ml.

Suprastin is contraindicated for newborns (including newborns born prematurely).

Injections are given with an insulin syringe with a needle for intramuscular injection. The maximum permissible dose of the drug is 2 mg/kg/day.

Overdose

Accidental or intentional overdose, especially in children, can cause death.

The symptoms and signs that occur with an overdose of Suprastin are similar to the symptoms of atropine poisoning. They are expressed in the form:

In young children, excitement predominates.

In some cases, sinus tachycardia, dry mouth, facial flushing, fixed dilated pupils, fever, and urinary retention occur.

In adults, facial flushing and fever are observed intermittently, with periods of agitation followed by convulsive seizures and postconvulsive depression. The patient develops coma, cardiac and respiratory failure. Death occurs within 2-18 hours.

Cardiorespiratory monitoring as well as symptomatic therapy are recommended. Suprastin does not have a specific antidote.

Interaction

Simultaneous use with MAO inhibitors helps to prolong and enhance the anticholinergic effects of Suprastin.

With caution, the medicine is prescribed with: tranquilizers, sedatives (including sedative analgesics), muscarinergic parasympatholytics, atropine, tricyclic antidepressants. This is due to the fact that in combination with Suprastin these drugs exhibit synergistic action.

Alcohol potentiates the inhibitory effect of chloropyramine on the central nervous system, and therefore, during treatment with Suprastin, drinking alcohol should be avoided.

Terms of sale

Suprastin in tablet form is available without a prescription; a prescription is required to purchase the solution.

Recipe in Latin for Suprastin tablets for allergies:

Rр.: Tab.Suprastini 0.025 No. 20

DS For oral administration (1 tablet 2-3 times a day with meals)

Storage conditions

The medicine retains its pharmacological properties at a temperature of 15-25°C. Both tablets and ampoules should be kept away from children.

Best before date

special instructions

The annotation states that the drug should be used with caution in elderly people, as well as in patients with heart pathologies and liver failure.

If taken in the evening, the drug may increase the symptoms of gastroesophageal reflux.

It should be remembered that chloropyramine can cause depression and drowsiness, interfering with certain types of activity. They are especially pronounced at the initial stages of treatment.

The doctor determines the degree of restriction on working with machinery and driving vehicles individually for each patient.

Application in veterinary medicine

Chlorpyramin can be used for drug therapy of allergic conditions in animals.

It is given orally 2-3 times a day. at a dose of 0.3-0.5 mg/kg. When administered intramuscularly, the dose for horses is ml, for pigs weighing kgml, for dogs the dosage depending on weight is from 0.1 to 0.5 ml. Injections are given 2 times a day.

Suprastin's analogs

Pharmaceutical equivalents of the drug are Chlorpyramin, Chlorpyramin-Ferein, Chlorpyramin-Eskom.

The price of analogues in tablets is rubles. 10 ampoules of the solution will cost approximately the same amount.

Which is better - Suprastin or Tavegil?

Both products are 1st generation drugs. The duration of the effect produced and the intensity of action are comparable.

Which is better - Cetrin or Suprastin?

Cetrin (cetirizine hydrochloride) is a 2nd generation drug that is a highly selective antagonist of H1-type histamine receptors.

The drug has 2 release forms - tablets, which are used in patients over 6 years of age, and syrup, which is prescribed from 2 years of age.

Cetirizine hydrochloride is practically not biotransformed in the body; the rate of its elimination is related to the functional state of the kidneys. A special feature of the drug is its ability to penetrate well into the skin, which makes Cetrin especially effective for skin manifestations of allergies.

The drug does not have a proarrhythmic effect, which has been proven in preclinical and clinical studies.

This means that the use of Cetrin is much less likely to be accompanied by the development of adverse reactions than the use of 1st generation products. Moreover, the degree of expression of the latter is also less than that of Suprastin.

If we talk about antiallergic activity, then Suprastin is considered a somewhat stronger remedy.

Which is better: Zyrtec or Suprastin?

Zirtec is a generic version of Cetrin, since both of these drugs contain the same substance - cetirizine. Thus, Zirtec has the same advantages over Suprastin as Cetrin.

Which is better - Suprastin or Diazolin?

The active substance of Diazolin is a blocker of histamine receptors of subtype 1, mebhydrolin, like chloropyramine, belongs to the 1st generation drugs. In comparison with its analogue, the product is characterized by less antiallergic activity. The sedative effect is slightly pronounced.

Suprastin or Zodak - which is better?

Zodak is a 2nd generation antiallergic drug with prolonged action. Its basis is cetirizine dihydrochloride, a substance characterized by the ability to selectively block peripheral H1-type histamine receptors.

It does not have a pronounced anticholinergic and antiserotonin effect. There is no sedation (including drowsiness) when used in therapeutic doses.

Which is better: Loratadine or Suprastin?

Loratadine is a 2nd generation antihistamine, which is characterized by high binding strength to peripheral H1-type histamine receptors. It has no sedative effect, does not have cardiotoxic effects and does not enhance the effects of alcohol.

Loratadine practically does not interact with other medications.

Which is better: Suprastin or Claritin?

Since the active ingredient of the drug Claritin is loratadine, the choice between it and Suprastin should be made taking into account the features described above.

Alcohol and Suprastin

The drug is incompatible with alcohol.

What is Suprastin? This is a first generation antiallergic drug. Like other drugs from this group, it has a pronounced anticholinergic, hypnotic and sedative effect, which is enhanced in combination with alcohol.

Suprastin and alcohol: consequences of simultaneous use

Drinking alcohol during treatment with Suprastin can provoke symptoms such as:

Suprastin during pregnancy and breastfeeding

Can pregnant women take Suprastin?

There are no data from preclinical studies on the use of the drug during pregnancy.

Adequate studies with proper control of the use of the drug in pregnant women have also not been conducted. However, there is evidence that newborn babies whose mothers took antihistamines during the last 2 weeks of pregnancy developed connective tissue behind the lens of the eye.

In the description of the drug, the manufacturer warns that the use of Suprastin - especially in the 1st trimester and in the last weeks of the 3rd trimester - is possible only after a careful assessment of the beneficial effects and possible risks.

As for use in the 2nd trimester, the drug is also prescribed during this period after the risks to the fetus and the benefits to the mother’s body have been analyzed.

Thus, the question of whether Suprastin can be taken during pregnancy can only be answered by a doctor monitoring a pregnant woman.

Suprastin during lactation: can nursing mothers take antihistamines?

In the absence of well-controlled, adequate data on the use of the drug in breastfeeding, it is not recommended for use in breastfeeding women.

Reviews about Suprastin

Reviews of Suprastin for children and adults prove the high antihistamine activity of this drug. The product is effective for the treatment of allergic rhinoconjunctivitis (both year-round and seasonal), urticaria, Quincke's edema, eczema, atopic dermatitis, itching of various etiologies.

In parenteral form, the drug has proven itself well in conditions that require emergency care.

The advantages of the drug are proven effectiveness, a wide range of therapeutic doses used, speed of action, short duration of side effects, controllability of the clinical effect, low cost. The active substance of the drug does not accumulate in the serum, which eliminates the possibility of overdose with long-term use.

Wikipedia indicates that Suprastin is included in the Russian list of vital and essential drugs.

How much do Suprastin tablets and injections cost?

The price of Suprastin tablets in Russia is from 110 rubles. The price of Suprastin in ampoules is from 150 rubles.

The average price in Ukraine for tablets 25 mg No. UAH, the price of Suprastin 25 mg No. 10 is from 29 UAH. The d/i ​​solution can be purchased in pharmacies in Kharkov and Kyiv. At the same time, the cost of 1 ampoule is UAH.

For patients who are more comfortable using drops, Egis has developed the drug Suprastinex based on levocetirizine. Its cost is from 1060 rubles. in Russian, and from 350 UAH in Ukrainian pharmacies.

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Nina: I was on pills for a year and a half, then somehow everything calmed down. Mostly climatefit.

Elena: With the onset of menopause, the skin completely deteriorated and became dry. I saw a cream for .

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Source: http://medside.ru/suprastin

Suprastin for allergies - instructions for use

Suprastin belongs to the 1st generation antihistamines and is used as an antiallergic agent for systemic use. Before use, you must read the instructions in detail!

Mechanism of action

Chloropyramine, the active ingredient in Suprastin, is a blocker of H1-histamine receptors responsible for the development of an allergic reaction.

Once in the human body, the allergen, with the participation of an antibody, forms an immune complex that settles on specific cells - basophils.

Next, the basophil ruptures and the release of inflammatory mediators, the main of which is histamine. Swelling, redness, local fever, pain and dysfunction are observed at the site of the allergen.

By blocking sensitivity to histamine, Suprastin inhibits all its effects and prevents the development of an allergic reaction.

Pharmacokinetics

When taken orally, Suprastin is completely absorbed from the gastrointestinal tract.

The effect is achieved within minutes and reaches 8 hours.

The maximum concentration in blood plasma is observed in the first 1-2 hours.

Well distributed throughout the body.

Metabolized by the liver, excreted in the form of metabolites in the urine.

Release form

  • tablets 25 mg, No. 20;
  • solution for injection 20 mg, ampoules 1 ml, No. 5

Photo: Two release forms

Advantages

  • proven high efficiency;
  • fast and pronounced therapeutic effect;
  • high bioavailability, regardless of the method of application;
  • possibility of use in emergency care due to the presence of an injection form;
  • no overdose with long-term use, as it does not accumulate in the body;
  • Possibility of use in infants over 1 month of age;
  • controllability of the clinical effect, the possibility of combining with long-acting antihistamines for prolongation;
  • the possibility of use for the treatment of non-allergic rhinitis due to its anticholinergic effect, which is manifested by a decrease in sneezing, rhinorrhea, swelling and nasal congestion;
  • local anesthetic effect;
  • antiemetic and anti-sickness effect;
  • antipruritic, sedative and hypnotic effect, especially important for allergic dermatitis and other itchy dermatoses;
  • short duration of possible side effects due to low accumulation in the body;
  • lack of cardiotoxic effect as in the second generation of antihistamines;
  • original foreign quality of all components of the drug;
  • low cost.

How to drink Suprastin for allergies

Allergy tablets Suprastin should be taken whole with meals and washed down with enough liquid.

How much to drink

You need to take Suprastin 1 tablet per day.

The maximum daily dose is 100 mg (4 tablets).

You need to drink for 5-7 days, but treatment is considered complete after the allergy symptoms disappear.

If side effects occur, the drug should be discontinued.

How are injections prescribed?

Suprastin ampoules for allergies are administered intramuscularly, daily dosage for adults is 1-2 pcs.

In acute and severe forms of allergies or anaphylactic shock, intravenous injection is recommended, followed by switching to intramuscular injections or taking tablets.

Which is better - injections or tablets?

The choice between the release form depends on many factors:

  • severity and speed of development of the allergic reaction;
  • age;
  • patient's body weight.

In the absence of an emergency, it is better for adults to take tablets.

Ampoules are used only in cases of severe, pronounced manifestations of allergies, the inability to take tablets orally (for example, loss of consciousness), or in young children due to the convenience of dosing by body weight, unlike tablets.

Indications

  • allergic rhinitis;
  • conjunctivitis;
  • hives;
  • contact dermatitis;
  • allergic reactions to foods, medications, insect bites, ultraviolet rays;
  • itching;
  • as part of combination therapy for systemic anaphylactic reactions and angioedema.

Contraindications

  • individual intolerance to the components included in the composition;
  • relief of an attack of bronchial asthma;
  • angle-closure glaucoma;
  • stomach ulcer;
  • acute myocardial infarction;
  • arrhythmia;
  • taking certain groups of antidepressants;
  • ischuria, prostatic hyperplasia;
  • hypersensitivity to other ethylenediamine derivatives.

Overdose

The drug is well tolerated and does not cause overdose in recommended doses, even with long-term treatment.

Symptoms of overdose are possible when the recommended doses are intentionally or accidentally exceeded.

  • hallucinations;
  • disorders of consciousness;
  • causeless anxiety followed by lethargy;
  • impaired coordination and motor skills of movements, with the development of athetosis and seizures.

In young children, the following occurs:

  1. stimulation of the central nervous system;
  2. dry mouth appears;
  3. the pupils dilate;
  4. hyperemia of the face and body;
  5. tachycardia, difficulty urinating, fever begins; in severe cases there may be coma.

In the first 12 hours from the moment of oral administration of the drug, it is necessary:

  1. detoxification therapy: gastric lavage, use of adsorbents;
  2. symptomatic treatment of low blood pressure and breathing;
  3. carrying out resuscitation measures if necessary.

There is no specific antidote.

Does it have a sedative effect?

Suprastin has a sedative and hypnotic effect. Slows down the activity of the nervous system, reduces reaction and concentration.

What do you need to know when buying allergy eye drops for children under one year of age? The answer is here.

It is important to know

  • there is no children's form of the medicine, ampoules are prescribed to children from 1 month, tablets are allowed from 3 years;
  • should not be taken during pregnancy and breastfeeding;
  • alcohol increases possible side effects;
  • Due to the sedative effect, the drug is contraindicated for drivers and people whose work requires high concentration in the initial period of therapy. During further treatment, after consultation with a doctor, the dose of the drug and duration of treatment are selected individually;
  • the drug should not be taken for gastrointestinal diseases, glaucoma, adenoma, or during an asthma attack;
  • when combined with drugs that have a toxic effect on the hearing system, Suprastin can mask the first signs by relieving swelling;
  • in case of liver or kidney diseases, there may be a need to adjust the dosage;
  • tablets contain lactose and are therefore not recommended for patients with lactase deficiency or galactosemia;

Features of use in children

  • 1–12 months: ¼ ampoule (0.25 ml);
  • 1 year - 6 years: ½ ampoule (0.5 ml);
  • 6–14 years: ½–1 ampoule (0.5–1 ml).

The maximum daily dose for a child is not more than 2 mg/kg body weight.

Prescription for pregnant women

Suprastin is not prescribed during pregnancy, as it can cause unpredictable consequences for the fetus.

Prescription during lactation

The drug is not prescribed during breastfeeding, as it passes into breast milk.

Video: How to give injections correctly

Special patient groups

  • in patients suffering from liver disease, due to decreased metabolism, a dosage adjustment of the drug may be required;
  • in patients suffering from kidney diseases, due to decreased excretion of the drug, a change in dosage regimen or dosage adjustment is often required;
  • Elderly, exhausted people should take the drug with extreme caution due to the frequent occurrence of dizziness and increased drowsiness in this category.

Interaction with other drugs

  1. potentiation of each other's effect is observed with the simultaneous use of Suprastin and sedatives or hypnotics, barbituric acid derivatives, tranquilizers, synthetic analogues of the opioid group, tricyclic antidepressants, atropine;
  2. the anticholinergic effect of Suprastin increases and prolongs when using monoamine oxidase inhibitors;
  3. alcohol increases the side effects of the drug, making it incompatible with treatment with Suprastin;
  4. 3-4 days before the appointment of skin allergy tests, the drug should be discontinued.

Conditions for release from pharmacies

Tablets can be purchased without a doctor's prescription, ampoules - strictly according to the prescription.

Storage conditions and shelf life

The storage temperature of the drug is from 15 to 25 C.

Must be stored in original packaging, out of the reach of children.

Shelf life: 5 years. Do not use after the expiration date!

Price policy

Suprastin belongs to the middle price category.

Depending on the region and pharmacy, the price for tablets varies from 120 rubles, for ampoules from 150 rubles.

In comparison with other foreign drugs, Suprastin is one of the most accessible and cost-effective.

Analogs

  1. chloropyramine-ESKOM – ampoules of 1 ml No. 5, 10 or 20 per package. Manufacturer OJSC NPK ESKOM, Russia;
  2. chloropyramine tablets No. 10, 20 per package; No. 10, 20, 30, 40, 50, 60 and 100 in a jar. Manufacturer: Atoll LLC, Russia.

FAQ

Why does the drug not help and what to do?

  1. incorrect dosage or frequency of taking the drug. If the dose is reduced below the threshold, there may be no effect.
  2. taking the medicine incorrectly. To ensure complete absorption of Suprastin from the gastrointestinal tract, it should be taken with meals, since the necessary acidic environment is created in the stomach.
  3. incorrectly diagnosed. If the medication was taken according to the instructions, but there was no effect, the diagnosis is most likely incorrect.

The most correct decision would be to seek help from a specialist.

How to choose effective and cheap allergy pills? Read in the article.

Reliable methods of treating allergies with folk remedies, further.

Is there a reaction to the drug itself?

Individual intolerance to the drug or its individual components is possible in any person, but drug allergies occur extremely rarely, in less than 15% of cases.

Or maybe Tavegil is better?

The drugs are similar in action and effect, but in each specific case they will manifest their properties differently.

The choice of drug will depend on the patient’s age and the specifics of his work.

A significant advantage of Suprastin is the possibility of use in young children.

Tavegil is prescribed only to children from 6 years of age. Unlike Suprastin, Tavegil does not have a pronounced hypnotic effect, but a sedative effect is present.

Suprastin, being an old generation drug, remains the most purchased drug in Russia for more than 3 years.

Its speed of action, severity of effect and wide range of use, both in the elderly and in children from a very early age, make it possible to prescribe it to almost all categories of patients with allergic manifestations of any severity.

The first time we developed an allergy was in the maternity hospital. I ate a carrot casserole and it made my son’s whole body all over him. They gave me a Suprastin injection for allergies, and the next day everything went away. Since then I only use it if my child gets wet. The main thing is to read the instructions for use and not exceed the dosage.

Suprastin was prescribed to me by my therapist when I developed an allergy to flowers. I had a very bad runny nose. After the first pills there was severe drowsiness and weakness. But the runny nose went away the very next day. I started taking one tablet at night throughout the flowering period. It helped very quickly and well.

I have a relative who is a dermatologist. I decided to ask why doctors most often prescribe Suprastin. She replied that they are and will continue to be prescribed, because this is the only medicine that acts on all types of allergens. Therefore, if the cause of the allergy is unclear, any doctor will most likely recommend Suprastin.

I give my child Suprastin because only it and Fenistil can be taken from an early age. Fenistil is very weak. Suprastin is much better. The child sleeps more, but the drug works.

Source: http://allergycentr.ru/suprastin-ot-allergii.html