Miramistin or chlorhexidine, which is better?

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Miramistin or Chlorhexidine

These two drugs are antiseptics. These drugs have a similar local antimicrobial effect. This is where their similarities end. In fact, these are 2 completely different drugs, and their active ingredients are also different.

Table of contents:

Chlorhexidine

In Chlorhexidine, the active ingredient is Chlorhexidine bigluconate. As you might guess, it is the presence of chlorine that is responsible for its antimicrobial activity. This activity is relatively low.

Chlorhexidine is active only against vegetative forms of bacteria, including E. coli, staphylococci, streptococci, as well as some types of viruses and fungi.

Chlorhexidine acts on microbial spores only at high temperatures. This remedy is used in the treatment of urogenital infections, infected wounds, and burns. Chlorhexidine is used in dental and ENT practice in the treatment of sinusitis and stomatitis, as well as in gynecology and obstetrics.

Release form – 0.05% solution, 0.5% spray for external use, vaginal suppositories. Chlorhexidine is a domestic product manufactured by Rosbio, TOS, Nizhpharm, Biogen under the names Chlorhexidine, Chlorhexidine bigluconate, Hexicon. Although calling this drug domestic can only be done with some reservations.

Chlorhexidine is produced abroad in the form of a concentrate, but here it is diluted and packaged in containers. Among the foreign manufacturers of Chlorhexidine are Pierre Fabre, France (Elugel gel) and Smith Klein, England (Corsodil solution). On the Russian consumer market there is a German combination drug Bepanten Plus - a combination of Chlorhexidine and Dexpanthenol.

Miramistin

Unlike Chlorhexidine, synthesized about 60 years ago, Miramistin has a more interesting “biography”. Development of Miramistin began in the Soviet Union in the second half of the last century.

The drug, code-named, was originally intended for use in space. After all, closed outer space is ideal conditions for the reproduction of “earthly” microbes. With the collapse of the USSR, all developments on Miramistin were put “on the shelf”. These developments were remembered relatively recently. They formed the basis of Miramistin.

This remedy is effective against many pathogenic bacteria, fungi, protozoa, and some viruses. Miramistin is synthesized by the Russian company Inframed in the form of a 0.01% solution for external use and Okomistin eye drops with the same concentration. Miramistin has no foreign analogues - it is only a Russian remedy.

Which is better - Miramistin or Chlorhexidine?

Miramistin has more advantages. Firstly, the antimicrobial activity of Miramistin is higher than that of Chlorhexidine. Its spectrum of action is also wider - many types of microorganisms are sensitive to it.

In addition, in addition to destroying microbes when applied to the skin and mucous membranes, it has a good anti-inflammatory, decongestant and wound healing effect. Miramistin has no contraindications. And for Chlorhexidine, these include skin diseases (dermatitis), childhood, pregnancy and breastfeeding. For treating the hands of medical staff and disinfecting surgical instruments, Chlorhexidine is preferable to Miramistin.

Source: http://farmamir.ru/2014/05/miramistin-ili-xlorgeksidin/

General and difference between Miramistin and Chlorhexidine

You can often come across the opinion that Miramistin and Chlorhexidine are interchangeable. Indeed, many people suffering from inflammatory diseases of the throat mucosa use one of these drugs of their choice.

Judging by the reviews, Chlorhexidine also effectively helps with bacterial throat infections, like Miramistin. Meanwhile, using the first drug instead of the second for this purpose is not entirely correct.

What is the difference between Miramistin and Chlorhexidine

Chlorhexidine is originally a skin antiseptic. It was first synthesized by British chemists in the mid-twentieth century. This is a monodrug that contains one active ingredient. Its chemical name is extremely difficult for the average person to understand. Therefore, for convenience, it is abbreviated to “chlorhexidine bigluconate.” Available in aqueous-alcoholic or aqueous solutions with a concentration of the active substance from 0.05% to 5%.

As is clear from the name of the substance, it is based on chlorine, which is a toxin not only for microbes, but also for humans. Let us remember that this is gas. In high concentrations it was widely used during the First World War as a weapon of mass destruction. If chlorhexidine is ingested at a concentration above 0.2%, gastric lavage is required. This solution has an aggressive effect on the mucous membranes. It will also ignite when heated or in contact with fire.

As you can see, despite its antimicrobial effectiveness, Chlorhexidine is not without some drawbacks, which Soviet chemists tried to eliminate. In the 1980s In the USSR, attempts are being made to synthesize an “ideal” antibacterial drug for the needs of space. Herculean work was carried out: out of more than a thousand prototypes, one was selected, which ultimately received the trade name “Miramistin”.

Miramistin is also a single drug, i.e. contains one substance without any auxiliary additives. This is benzyldimethyl ammonium chloride monohydrate in aqueous solution.

In Russian medical practice, Miramistin began to be widely used in the early 2000s. It is difficult to find a more universal drug: it is used in urology and venereology, surgery and dermatology, obstetrics and gynecology, dentistry and otorhinolaryngology.

Thus, we can highlight at least 2 points regarding the difference between Miramistin and Chlorhexidine:

  • more favorable safety profile;
  • extremely wide scope of application.

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What Chlorhexidine and Miramistin have in common

Let's compare Chlorhexidine and Miramistin, highlighting those characteristics that are common to both drugs:

  • antibacterial antiseptics;
  • high activity, incl. against fungi, viruses, due to damage to the shell of microorganisms;
  • retain a bactericidal effect in the presence of blood and pus;
  • there have been no recorded cases of microbial resistance to them.

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Scope of application of Miramistin and Chlorhexidine

Let's analyze the difference between Miramistin and Chlorhexidine in the following table.

Table 1. Differences between Miramistin and Chlorhexidine by area of ​​application

Only in some cases: As you can see from the table, Miramistin and Chlorhexidine are not the same thing.

  • in urological and gynecological practice;
  • for disinfection of wounds, burns;
  • for the treatment and prevention of STIs -

Miramistin can be a substitute for Chlorhexidine.

Advantages and disadvantages of drugs

The difference between Chlorhexidine and Miramistin is clearly visible after analyzing their advantages and disadvantages.

Table 2. Comparison of some characteristics of Chlorhexidine and Miramistin.

What is better for the throat Miramistin or Chlorhexidine

Chlorhexidine is included in drugs with different trade names:

Solutions with an active substance concentration of 1%-5% are used for treating medical instruments, hands, and surfaces in medical institutions.

Solutions with a concentration of 0.5% -1% - also for disinfecting burns and wounds.

The solutions listed above cannot be used for the throat, because firstly, they cause severe irritation of the mucous membrane, and, secondly, when they enter the digestive system they cause poisoning.

Solutions with a concentration of 0.05%-0.2% are used for the following purposes:

  • for treating wounds, cuts, infected burns;
  • for bacterial skin lesions;
  • in the treatment of sexually transmitted infections;
  • in dentistry.

Mention should be made of chlorhexidine-containing drugs such as Hexicon (0.05%) and Amident (0.15%). Due to their low concentration, they are better tolerated; when they enter the digestive system, they are absorbed in extremely small quantities. Amident, among other things, contains glycerol and mint oil, which have a softening effect on the mucous membrane.

Low concentration chlorhexidines generally do not cause irritation and are practically not absorbed. However, Miramistin for the throat is still preferable:

  • the instructions for use indicate that this is a remedy for the treatment of pharyngitis, tonsillitis, laryngitis;
  • the drug has neutral taste;
  • well tolerated;
  • indicated for use by all categories of patients.

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Analogues of Miramistin and Chlorhexidine

There are no analogues of Miramistin.

Chlorhexidine is included in some compound throat medications:

Analogues of Miramistin and Chlorhexidine according to indications for use are numerous. Here are the most common:

The active substances in the listed drugs are different from those contained in the drugs discussed in this article.

Conclusion

If you compare the composition of Chlorhexidine and Miramistin, it becomes clear that these drugs are different. However, in terms of application they are quite close to each other.

Preparations containing chlorhexidine in a concentration of 0.05%-0.2% can be used to treat inflammatory diseases of the throat and oral cavity.

However, when deciding which is better for the throat from sprays - Miramistin or Chlorhexidine - you should give preference to the first drug.

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Do you have a question or experience regarding this issue? Ask a question or tell us about it in the comments.

She treated inflamed gums with chlorhexidine when the wisdom tooth was erupting. Good help. Then I only found out that it was possible to take Metrogyl Denta, and that it already contained chlorhexidine. And I often treat my throat with Miramistin. It seems to me that each of them is good in its own way.

We read the article carefully, it is approved for use in space and this is better than anything and every day

a good old analogue that kills all microbes and regenerates is a solution of ethacridine lactate (0.1%). Here on the skin, on the mucous membrane. it was widely used in surgery for purulent lesions. Nowadays it is rarely found anywhere, sold as RIVANOL 0.1% (yellow liquid), but you can buy ethacridine powder (1g) at the pharmacy and dilute it at home as needed and syringe as needed.

All the advantages of Miramistin end with the fact that, unlike chlorhexidine, it is a drug with unproven effectiveness. Yes, it may kill the HIV virus in a test tube, but no one has tested it in the body. Horhexedine has passed all the tests required by WHO, and a huge number of independent ones, unlike the same Miramistin.

Miramistin, unlike chlorhexidine, even helps against viral infections. But chlorhexidine, it seems to me, is stronger as an antiseptic; it is not for nothing that surgeons treat their hands with it before operations, and chlorhexidine was also included in the composition of Metrogil Dent. It kills bacteria more actively, so you need to be careful with it.

Chlorhexidine helps better against thrush, although it is cheaper. I’ve been suffering for several months now, I’ve tried everything, and now I’ve switched to a flucostat with normospectrum. But among local remedies, chlorhexidine and Metrogyl gel are really the best.

Ethacridine lactate helped me, it just doesn’t wash off as easily as chlorohexidine and penetrates the mucous membrane longer and deeper

All my life I thought that wounds were washed with chlorhexidine before applying metrogyl, and sexual infections were treated with miramistin. but here, it turns out, they can be used for sore throats, and it is still unknown which is better. but the price, of course, is noticeably different...

You know, a high price does not mean that the drug is better, take at least Solantra: it costs 15 times more than Metrogyl, if not more, and is tolerated many times worse, it’s as if the skin was scorched by fire. I took it and regretted it. The same can happen with Miramistin. You overpay, but where is the guarantee that it will help better?

I beg you... Solantra used to be used to treat cows for parasites, read it on the net. It’s better to be treated with Metrogil.

Source: http://www.pulmonologiya.com/preparaty/bol-v-gorle/miramistin-ili-hlorgeksidin.html

What is the difference between Miramistin and Chlorhexidine?

Antiseptic drugs are used to treat wounds, abrasions, and sutures that occur after surgery. These substances will destroy pathogenic bacteria and microorganisms, preventing inflammation. The most popular and effective modern antiseptics are miramistin and chlorhexidine. Both of these drugs have similar uses and belong to the same drug group. However, there are a number of significant differences between them.

Chlorhexidine or Miramistin: which is better?

There may be contraindications, consult a specialist

Let us carry out a comparative description of these drugs. The main chemical substance corresponding to the name and release forms of the drug is what, first of all, distinguishes Miramistin from chlorhexidine. Since it is different in these drugs, some features of their use and the range of effects also differ.

Scope of application of Miramistin with Chlorhexidine

Thus, the action of miramistin is aimed at combating fungi and various pathogenic viruses. Chlorhexidine destroys all types of bacteria, viruses and certain types of yeast. These drugs can act as analogues for the following actions:

  1. For the treatment (treatment) of wounds, burns, abrasions, surgical sutures.
  2. For auxiliary treatment of gynecological and urological diseases.
  3. For the treatment of a number of dental diseases.
  4. As an antiseptic and disinfectant for household injuries.
  5. As a prevention of sexually transmitted diseases. True, there are no special statistics on this matter. As you know, to protect one hundred percent, nothing like that has been invented yet. And with post-processing it’s even more complicated; the effectiveness of these tools depends on many factors. Perhaps there are three main recommendations: 1 - the faster, the better; 2 - do everything exactly according to the instructions; 3 - do not consider these solutions a panacea and do the appropriate tests.

In addition, chlorhexidine is used for the treatment and disinfection of surgical instruments and equipment, and various medical instruments. Miramistin is not suitable for these purposes. So, the difference between chlorhexidine and miramistin lies in the area of ​​influence and medical purpose of these antiseptics. In the latter it is more extensive and universal.

Advantages and disadvantages of Chlorhexidine and Miramistin

Miramistin is considered a new generation antiseptic. It has virtually no contraindications or age restrictions, accelerates the regeneration of the skin, has an anti-inflammatory effect, and increases the overall immunity of the body.

Chlorhexidine bigluconate is a time-tested antiseptic drug. Due to its accessibility and effectiveness, it has gained wide popularity among patients and physicians. This product perfectly cleanses the skin without causing damage or irritation. Has antibacterial and disinfectant properties. The use of chlorhexidine is recommended in cases of burn wounds, infectious and inflammatory processes of a dental and gynecological nature. It is also used to disinfect the skin of medical staff’s hands and medical instruments.

The main difference between chlorhexidine and miramistin is that the latter drug has significantly fewer side effects. In addition, chlorhexidine is contraindicated for dermatitis and a tendency to allergic reactions. Also, the use of this product is not recommended for children, nursing mothers and pregnant women.

What is cheaper - miramistin or chlorhexidine?

It should be noted that the cost of chlorhexidine is an order of magnitude lower than the cost of its opponent. In pharmacies it is presented in the form of a ready-made solution, packaged in containers of one hundred milliliters. The average price of such a bottle is about rubles. A bottle of Miramistin of the same volume will cost much more, from 250 to three hundred rubles. Thus, it turns out that the price for it exceeds the cost of chlorhexidine by twelve and a half times. The difference is quite significant. However, although these two types of antiseptics have similar properties and in some cases act as analogues, it is not always possible to replace Miramistin with the more accessible chlorhexidine. When making a decision in each individual case, you should consult your doctor.

In summary, it is impossible to say unambiguously and accurately that miramistin or chlorhexidine is more effective, since everything depends on the individual characteristics of the patient and the purpose of using the drug. According to medical professionals, Miramistin is better suited for the treatment of skin diseases such as dermatomycosis, athlete's foot, keratomycosis, etc. But chlorhexidine is more effective for sanitary purposes, disinfection of premises, hygienic treatment of hands and instruments before various medical procedures (childbirth, dressings, surgical operations, etc.).

Comments

Miramistin also helps against viruses; I spray it in children’s throats for acute respiratory infections. And chlorhexidine treats acne well, I use it as a toner together with Metrogyl.

Source: http://www.kliwi.ru/2015/08/chem-otlichaetsya-miramistin-ot-hlorgeksidina.html

Drugs "Miramistin" and "Chlorhexidine": what is the difference? Reviews

When purchasing a particular medicine, a person almost always wonders whether it is possible to purchase an analogue at a more affordable price. Modern pharmacology offers its consumers a lot of similar and interchangeable products. These will be discussed in today's article. You will find out what the difference is between Miramistin and Chlorhexidine, and you will also be able to read reviews about these drugs.

Preliminary characteristics

Before you learn about the medications “Miramistin” and “Chlorhexidine” (what is the difference), it is worth getting to know these medications better. Both products are good antiseptics. You can purchase them without a doctor's prescription at any pharmacy. They are sold in different volumes and forms. Containers with a sprayer are designed for ease of use.

Many patients believe that the drugs Miramistin and Chlorhexidine are the same drug. What is the difference between them - people do not see. Despite this, there are still differences. Medicines have their own characteristics. Let's take a closer look at the existing differences and find out whether it is possible to replace one medicine with another.

Price category

There is a significant difference between Miramistin and Chlorhexidine in price. As you already know, both drugs can be purchased without a prescription at the pharmacy. The containers in which they are sold are different. For 50 milliliters of Miramistin solution you will have to pay about 250 rubles. Antiseptic "Chlorhexidine" is cheaper: no more than 20 rubles per 50 milliliters.

Patients often report that preference is given to Chlorhexidine. All because of the attractive cost of the drug. People often have the misconception that medications are the same. If you delve deeper into the composition of the drugs, you can find out that the solutions have different chemical formulas. Miramistin contains benzyldimethyl ammonium monohydrate, and Chlorhexidine contains chlorhexidine digluconate. This is the first and main difference between the drugs. After all, the method of operation and effect of the medicine depends on the composition.

Scope of use

What can be said about the use of the medications Miramistin and Chlorhexidine? What is the difference? For angina, both of these remedies are used by patients to treat tonsils and an inflamed larynx. They eliminate bacterial plaque and disinfect mucous surfaces. They are also used for irrigation of other areas: in gynecology, dentistry, otorhinolaryngology, surgery.

Both drugs are effective against bacteria. Miramistin also copes with complex viral infections; it actively destroys the herpes virus, HIV and others. "Chlorhexidine" is not able to cope with such things. So, the second difference between drugs is their method of action.

Indications and contraindications described in the annotation

To find out in more detail about the Miramistin and Chlorhexidine solutions (what is the difference between them), you should refer to the instructions. The annotation states that both antiseptics are intended for treating the surface of the skin. The instructions recommend using “Chlorhexidine” to disinfect surgical instruments and hard surfaces. It should be used to clean the hands of medical personnel and kitchen workers. The abstract about Miramistin states that the solution is used to treat inflamed skin, wounds, cuts and burns. It is used to irrigate mucous membranes. This medicine is also used to treat children (pharyngitis, rhinitis, stomatitis).

Both medications cannot be used if you are highly sensitive to the active substance. The difference between them is that Chlorhexidine cannot be used for children or for allergic skin reactions. The instructions state that the concentrated solution can be dangerous to humans, since treatment with it causes burns and skin damage.

Method and duration of use

If we talk about the method of using the drugs “Miramistin” and “Chlorhexidine” - what is the difference? The Chlorhexidine solution is applied to the skin (in particular, hands) for two minutes. When it comes to processing hard surfaces and tools, it is used in unlimited quantities. Vaginally, the drug is administered exclusively in the form of suppositories. To irrigate the mucous membranes, the medication is used for no more than 7 days in a row. This is the doctor's recommendation.

Doctors prescribe Miramistin for a longer period. Since the effect of the drug is mild, it can be used for an unlimited time. It is recommended to use an antiseptic for irrigating the tonsils and throat for tonsillitis or pharyngitis. It is permissible to administer the medicine into the nasal passages for rhinorrhea. The medication is also used vaginally. This antiseptic is prescribed for the purpose of prevention or treatment.

Adverse reactions and discomfort while using drugs

Both medications can trigger allergies: Miramistin and Chlorhexidine. What's the difference for the nose? After application to the mucous membranes, antiseptics cause a burning sensation. In the case of Miramistin, it passes very quickly and usually does not cause discomfort to the patient. The use of Chlorhexidine intranasally is fraught with an unpleasant burning sensation and dryness, which take a very long time to disappear. When treating the throat, Miramistin does not create discomfort. Chlorhexidine has an unpleasant bitter taste.

The use of Miramistin rarely causes adverse reactions. In most cases, the medication is well tolerated even by young children. "Chlorhexidine" can irritate the skin and mucous membranes, dry it out, and cause severe allergies. There are known cases where treatment of the oral cavity with Chlorhexidine caused staining of teeth, destruction of enamel, tartar deposition and taste disturbances.

Additional Information

What other data is there on the drugs Miramistin and Chlorhexidine? What's the difference for the throat? As you already know, the latter solution has a bitter taste. Therefore, its use for the treatment of the larynx and tonsils may be uncomfortable. If you accidentally swallow Miramistin, you should not expect any unpleasant consequences. But if Chlorhexidine gets inside, it’s dangerous. If the medication is accidentally swallowed, immediately induce vomiting and rinse the stomach.

The drug "Miramistin" can be used in ophthalmology. It is used to treat eyes with conjunctivitis. The use of Chlorhexidine in this area is contraindicated. If the drug gets into your eyes, rinse them immediately with plenty of water. After this, be sure to see a doctor. The medication may cause severe burns.

"Miramistin" and "Chlorhexidine": what is the difference?

Consumer reviews often report that these solutions are the same. In fact, there are enormous differences between medications. They cannot be interchanged.

Patients can see from their own experience that the medications are different. The drug "Chlorhexidine" when treating mucous areas causes burning and redness. Consumers report an unpleasant bitter taste that sometimes causes vomiting. Antiseptic Miramistin, according to users, is quite expensive. But at the same time it has its advantages. The solution gently treats mucous areas and does not cause irritation. It is easy to use for children. The medicine does not have a bitter taste, it resembles ordinary water. The effectiveness of the solution has been confirmed by research. It eliminates both bacterial, fungal and viral infections.

Many patients are perplexed: what is the difference between Miramistin and Chlorhexidine, what is the difference? For inhalations, according to medical opinion, only the first antiseptic can be prescribed. It is used for bacterial and viral bronchitis, tracheitis. The drug "Chlorhexidine" is prohibited to be administered by inhalation. Such treatment can cause severe burns of the respiratory tract and mucous membranes. As a result, therapy not only will not bring relief. You will have to deal with the consequences of such treatment.

Instead of a conclusion

As you can already understand, Miramistin and Chlorhexidine only at first glance seem the same. Their purpose is completely different. Therefore, if you have been prescribed Miramistin, you should not replace it in order to save money. Improper use of the drug entails unpleasant consequences, the elimination of which can cost you much more. Before using any drug, be sure to read the leaflet that comes with it. Treatment of children should be coordinated with a doctor. Good health to you!

Source: http://www.syl.ru/article/283162/new_preparatyi-miramistin-i-hlorgeksidin-v-chem-raznitsa-otzyivyi

Miramistin and Chlorhexidine - what is the difference between the drugs?

The range of medical antiseptics is wide. They are used to treat the surgical field, treat instruments, combat pathogens and prevent recurrent bacterial contamination. Popular Miramistin and Chlorhexidine. Patients ask: “Is this the same thing? Miramistin and Chlorhexidine - what is the difference? We will tell you in detail about the main differences and areas of application of antiseptics.

Is there a difference in the composition of Miramistin and Chlorhexidine?

There are differences between the composition of the drugs. Antiseptics are based on the chemicals that give them their name. The formula allows Miramistin to act on a large number of pathogens. Chlorhexidine does not have such a broad spectrum, but the attitude of most patients and doctors is positive. This is confirmed by various reviews on medical and cosmetology forums.

Comparing drugs is not always correct. But often one antiseptic replaces another. Therefore, when choosing, you should listen to the doctor’s advice, look at the individual reaction, therapy or prevention.

The principle of action of antiseptic drugs

The principle of all antiseptics is similar. Active chemicals dehydrate the protective shell of the pathogen, cause coagulation and denaturation of protein compounds. Therefore, the microorganism dies after contact with Miramistin or Chlorhexidine. At the same time, the effect of the antiseptic does not affect healthy tissues and cells of the body and does not interfere with regeneration. Depending on what type of microbe causes the disease, doctors select antiseptics. Therefore, before starting therapy, it is necessary to consult with specialists.

Indications for the use of antimicrobial solutions

According to the instructions, the drug Chlorhexidine can be used for:

  • Disinfection of surfaces and instruments;
  • Therapy of bacterial or fungal lesions of the skin.

Antiseptic Miramistin has a wide range of uses. Indispensable for:

  1. Purulent-inflammatory processes of the nasopharynx. The spray form allows you to apply the medicine evenly to the affected mucous membrane;
  2. Ailments of bacterial and fungal origin of the reproductive system. Gynecology uses Miramistin for candidiasis in men and women, inflammation of the urethra;
  3. During unprotected sexual intercourse;
  4. Inflammation of the nasopharynx and mucous membrane of the eyes;
  5. As a treatment for postoperative or other wounds and violations of the integrity of the skin.

Instructions for use of Miramistin and Chlorhexidine

The drug does not protect against sexually transmitted infections as effectively as other antiseptic medications. To prevent the development of fungus, inject 2-3 ml of solution into the urethra and treat the external genitalia with a cotton swab. For the treatment of candidiasis of the reproductive system of various types, therapy is carried out for 10 days.

After dental or ENT operations, the damaged area is irrigated with a 0.05% solution. The quality of treatment and its frequency affect the duration of therapy. After surgery or during purulent-inflammatory processes, the drug is used at least 4 times a day. This multiplicity provides a high therapeutic effect, fungal activity decreases. A child cannot always allow himself to be treated with a solution. Therefore, it is worth looking for analogues of Chlorhexidine in the form of a spray.

To prevent fungal infections of the feet and nails, shoes are treated with an antiseptic every 5 days. If the disease is in the active phase, the solution is used for sanitation daily.

Antiseptic treatment is carried out before manipulation. Medical and manicure instruments are wiped with a solution of medicine.

Miramistin has an antifungal effect. Therefore, it is effective in the prevention and treatment of various ailments. Gingivitis, stomatitis and other diseases of the nasopharynx (nose and maxillary sinuses) and oral cavity require treatment with an antiseptic spray at least 3 times a day.

During unprotected sexual intercourse, the genitals are treated with an antiseptic at least 2 hours after the act. Otherwise, preventing fungal diseases will be problematic. An antiseptic is injected into the urethra; try not to urinate after the procedure for 2 hours. It is worth remembering that the drug does not protect against viruses and pregnancy. Therefore, it is optimal to combine several types of contraception.

Contraindications are taken into account during therapy. Pregnant women and those with allergy-prone skin should avoid the solution. The drug is also not allowed on surfaces after a chemical, thermal or sunburn. Instead of Miramistin or Chlorhexidine, a safe external analogue is used. Then the body’s reaction will not be violent, and treatment will not be problematic.

Which is better: Miramistin or Chlorhexidine?

Each person independently determines which drug copes better with the task. Both solutions can be used at home, hospital or beauty salon. Miramistin solution has a wide spectrum of action. It is equally suitable for treating skin, mucous membranes or manipulation instruments. An antiseptic is indispensable for purulent-inflammatory processes of the nasopharynx or genital organs. This is evidenced by positive reviews from those who treated purulent wounds and other similar problems. It is more effective to use Miramistin with other medications. The duration of therapy is determined only by the doctor.

The price of the analogue is more affordable. Therefore, chlorhexidine has been widely used in various industries. Without it, it is impossible to disinfect instruments in cosmetology and manicure. On sensitive skin, after contact with the solution, an allergic burn is possible. Therefore, it is not always permissible to use the substance. Otherwise, dermatitis, discomfort and pain will begin to poison your life.

Dermatologists advise that before choosing an antiseptic drug, compare the composition, decide on the purpose of use, and, if necessary, select a substitute. Then the use of Miramistin and Chlorhexidine will only bring positive results.

What is the difference (comparison of drugs)?

Miramistin differs from Chlorhexidine:

  • Scope of use. The instrument can be treated and the skin can be wiped with Chlorhexidine. Miramistin is more versatile in this regard. The solution is used for the throat, eyes and nose. Contact of Miramistin with the mucous membrane does not cause discomfort during or after use. Sensitive skin reacts calmly to the active ingredient. Contact with the mucous membrane of Chlorhexidine requires immediate medical attention: rinsing the area with cool running water. This is the main difference between the solutions. Therefore, rinsing the nasopharynx is not done with Chlorhexidine. After all, the treatment is unsafe and can cause burns;
  • Price. Miramistin spray costs a couple of times more than Chlorhexidine solution. Therefore, before choosing a drug, you should pay attention to this nuance.

If all the rules are followed, therapy with Miramistin and Chlorhexidine will bring positive results, and the virus, bacteria, infection will quickly recede under the onslaught of the antiseptic.

Source: http://wjone.ru/433-miramistin-i-hlorgeksidin-v-chem-raznica

Miramistin and Chlorhexidine: what is the difference and what is better in one case or another?

Among the wide selection of pharmaceuticals, there are often analogues - drugs that have the same active ingredient, but different auxiliary components and trade names.

You can often hear the opinion that Miramistin and Chlorhexidine are analogues and that the difference between them is only in price. Is this really so, or is there still a difference?

Let's start with the fact that these drugs are functional analogues. These are antiseptic drugs with bactericidal and antiviral effects.

The main scope of application is the prevention and therapy of dental, gynecological and ENT diseases, disinfection, asepsis and antiseptics.

Indications for the use of both Chlorhexidine and Miramistin are:

  • treatment of pustular, inflammatory and fungal diseases of the oral cavity (gingivitis, periodontal disease, candidiasis, etc.);
  • complex therapy of skin diseases, superficial wounds, burns, frostbite;
  • ENT diseases;
  • therapy of fungal diseases of the skin and mucous membranes;
  • both medications have found wide use in obstetric practice for inflammatory diseases of the female genital organs, including in the case of cervical erosion;
  • treatment and prevention of sexually transmitted diseases;
  • urethritis, ureoprostatitis of various nature;
  • disinfection of consumables, work surfaces, equipment, hygienic treatment of the hands of medical personnel and the surgical field.

Thus, medications suppress microbial flora and are also active against mycoses and infections of viral etiology.

Before assessing what is really better to use in a given situation, Miramistin or Chlorhexidine, let’s get to know our “rivals” and “neighbors” on the pharmacy shelf better.

Briefly about Miramistin

The active ingredient of the drug is benzyldimethyl-myristoylamino-propylammonium. Concentration of the solution for topical use is 0.01%

This is a broad-spectrum antiseptic, its effect is due to interaction with the lipid layer of the cell membrane of microorganisms and its cytolysis.

Predominant activity is observed against gram-positive microbes (pathogenic cocci: staphylococci, streptococci), as well as gram-negative ones, including anaerobes (clostridium gas gangrene, tetanus, botulism) and aerobes (mycobacterium tuberculosis), spore- and non-spore-forming.

It affects hospital strains, including those multiresistant to antibiotics - these are colonies of microorganisms specific to a medical institution that cause purulent-septic diseases in patients as a result of their hospital stay.

Miramistin has hyperosmolar properties, adsorbs purulent exudate, dries, neutralizes inflammation in the wound surface, has the ability to regenerate without damaging the newly formed tissue and marginal epithelium.

It has a local immunostimulating effect by activating the monocyte-macrophage system.

It is most effective in the following cases:

Features of Chlorhexidine

The active substance is Chlorhexidine bigluconate. Available in the form of solution, spray and vaginal suppositories.

The mechanism of action of the drug is based on interaction with the surface of the microbial cell, which results in an imbalance of water and electrolyte balance in the cell and it dies. Retains its activity in the presence of purulent discharge, blood, and exudate.

Vaginal suppositories are effective in the treatment and prevention of vaginal infections and also in the sanitation of the birth canal in preparation for childbirth and in the postpartum period. They can be used in any trimester of pregnancy and lactation.

The gel is used for treating the skin and mucous membranes, for complex acne therapy, and in dentistry for skin care after various procedures.

A solution for external use at a concentration of 0.05% is effective mainly in the prevention of sexually transmitted diseases and for the disinfection of wounds and abrasions.

A 1% solution is used for asepsis of equipment and surfaces in medical institutions.

Comparison of scope and contraindications

The scope of use of medicines is largely similar: dentistry, surgery and purulent surgery, dermatovenereology, otorhinolaryngology, obstetrics and gynecology, urology, cosmetology.

But, due to the fact that the composition of Chlorhexidine and Miramistin is different, there is some difference in the indications for use.

Chlorhexidine can rather be called an industrial drug. It has slightly lower activity and is insensitive to it, for example,

Pseudomonas under a microscope

Pseudomonas - Pseudomonas aeruginosa, opportunistic for humans, which causes nosocomial (nosocomial) infections, Proteus, which causes foodborne toxic infections, as well as acid-fast microorganisms, mainly Koch's bacillus - the most dangerous causative agent of tuberculosis in various organs.

Bacterial spores, intracellular formations formed by microbes to protect against environmental factors, are also insensitive to Chlorhexidine.

It is mainly used in hospitals and clinics for processing dressings, implants and catheters, disinfecting the hands of medical personnel, the surgical field, surgical instruments and devices that cannot be disinfected in an autoclave under pressure and hot steam.

The medicine is only suitable for external use on the skin and mucous membranes: it should not be used to wash the conjunctiva and cavities. It also does not combine with an alcohol solution of iodine.

Use with caution in children - the safety of the drug in pediatrics has not been proven.

Miramistin, unlike Chlorhexidine, is much more effective for the treatment of dental diseases, the treatment of various skin diseases - streptoderma and staphyloderma, the treatment of infected wounds, bedsores, ulcers, burns and frostbite. It is believed that it has a milder, more gentle effect on the tissues of the human body, but a wider spectrum of action on microorganisms - it is active even against strains that are multiresistant to antibiotics.

It is worth considering that when Miramistin and antibiotics are used together, microorganisms lose their sensitivity to the latter.

It is best used for infections of viral etiology - it is active against complex viruses, even the human immunodeficiency virus (HIV). It has a pronounced antifungal effect - for mycoses it is better to use Miramistin rather than Chlorhexidine.

And most importantly, Miramistin can be used to treat childhood skin diseases, in pediatric otorhinolaryngology and dentistry, during pregnancy and breastfeeding.

What is the difference and commonality?

The main differences between Miramistin and Chlorhexidine:

  • the former has a wider spectrum of action and scope of application;
  • more favorable when acting on mucous membranes - does not cause discomfort, burning, irritation, allergic reactions;
  • is safely used for the treatment of pregnant and nursing mothers, as well as in pediatrics;
  • has a local effect, without systemic influence.

In this case, Chlorhexidine:

  • has a narrower spectrum of action;
  • may cause a burning sensation when applied to the wound surface and mucous membranes;
  • has side effects - dermatitis, allergies;
  • not used for the treatment of children under 18 years of age and during pregnancy;
  • may have a systemic effect.

Some general points can be highlighted:

  • functional analogues – antiseptics;
  • do not cause resistance in microorganisms;
  • the same mechanism of action - they act on the cell membrane of the microbial cell, causing the destruction of the microorganism;
  • used in various branches of therapy;
  • active in the presence of pus and/or blood in the wound.

Cost comparison

The average price of Miramistin 0.01% 50 ml in Russian pharmacies is 200 rubles (the price varies depending on the nozzle), 150 ml - 350 rubles, 500 ml - 750 rubles.

The average price of Chlorhexidine solution 0.05% 100 ml is 10 rubles, vaginal suppositories 10 pcs - 150 rubles per pack.

To summarize, we can say that any use of antiseptics is advisable only as prescribed by a doctor. The exception is local treatment of the skin for scratches and abrasions.

Miramistin and Chlorhexidine are not always interchangeable, and if the doctor prescribes the first, then you should not replace it with the second. They have different active ingredients and their own characteristics of use.

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What is better - Miramistin or Chlorhexidine?

Both drugs are reliable antiseptics. Quite often they are offered as interchangeable drugs. But there is a difference between them that is noticeable even to people far from medicine - Miramistin is several times more expensive than Chlorhexidine.

On the one hand, thrifty relatives and “people from the Internet” can insist on Chlorhexidine, reproaching doctors and pharmacists for wanting to sell the product at a higher price and profit from those who believe that more is better. On the other hand, doctors and pharmacists, who can indeed sometimes insist on purchasing more expensive drugs. So is it worth overpaying? And if so, then in all cases?

Miramistin and Chlorhexidine

Given the obvious similarity of these two drugs, the fact that both of them are simultaneously found in pharmacies is not accidental, and is justified not only by a purely economic principle - to cover the maximum number of “focus groups”, that is, both richer and poorer people.

Both of these drugs are really relevant; to understand the difference, it is worth considering them in detail separately.

Area of ​​application of Miramistin

It is worth noting right away that if there is no way to consult with a specialist and there are any doubts as to whether a given surface or wound can be treated with an antiseptic, choose Miramistin from these two drugs.

The only area not recommended by pharmacists for the use of Miramistin is ingestion by an infant or accidental exposure to the infant's oral cavity. This limitation is not due to any contraindications, but only to the fact that oral administration of this drug by infants has not been studied by specialists.

This drug was developed to combat harmful microorganisms in spacecraft and the highest requirements were placed on it. The drug had to successfully destroy all known harmful viruses, fungi, bacteria, protozoa, but at the same time be as safe as possible when used.

Currently, Miramistin is most actively used:

  1. In gynecology.
  2. For the prevention of sexually transmitted diseases.
  3. In inflammatory processes on the mucous membrane.
  4. For ENT diseases.
  5. For disinfection of purulent inflammations.
  6. When treating burns and open wounds.

To the latter, it is worth adding that Miramistin can even accelerate the regeneration process if the wound is superficial and only involves damage to skin tissue. Miramistin can also be used to disinfect medical instruments, hands, and even shoes and clothes - but this is too expensive.

Instructions for use of Miramistin

It is very simple to use Miramistin due to the virtual absence of contraindications. In the case when treating an open surface, it is enough to pour a sufficient amount of the drug through the dispenser so that it covers the surface that needs treatment.

If it is not an open wound, you can use a piece of sterile cotton wool to save the drug. To treat sore throat, it can be used as a gargle and is absolutely harmless.

To use it in the prevention of sexually transmitted diseases, it should be poured, using a convenient lid, into the vagina or urethra, and the mucous membrane should also be treated from the outside.

Areas of application of Chlorhexidine

Chlorhexidine is a fairly old remedy, defined as a cheap analogue of Miramistin. It was developed in Great Britain back in the early fifties, but it cannot be called outdated. The range of its medical use was constantly expanding until the beginning of two thousand tenths. First of all, it is a fairly good antiseptic for external and local use.

Unfortunately, it has a number of negative features:

  1. It does not lead to the death of all harmful microorganisms.
  2. Long-term use on the mucous membrane can cause a number of unpleasant consequences.
  3. Suitable for anti-venereal treatment only in emergency cases, no later than two hours after sexual intercourse.
  4. Among viruses, it is quite effective only against herpes. First of all, it is an antibacterial agent.
  5. Upon contact with blood or pus, the effectiveness of the drug is reduced.

The drug is well suited for household antiseptic hand treatment, as well as for the treatment of medical instruments. The concentrated solution is used for sterile cleaning both in medical institutions and at home. Recently, it has also begun to be used in some clinics to treat the clothes of patients and medical staff.

At home, people have also found cosmetic uses for it - they use it to make face masks and use it to treat the skin after shaving.

Instructions for use of Chlorhexidine

Chlorhexidine is used externally and locally as a prophylactic and therapeutic agent. Aqueous solutions of 0.05, 0.2 and 0.5% are used in the form of irrigation, rinsing and applications - 5-10 ml of solution is applied to the affected surface of the skin or mucous membranes with an exposure of 1-3 minutes 2-3 times a day (for tampon or by irrigation).

Treatment of medical instruments and working surfaces is carried out with a clean sponge moistened with an antiseptic solution or by soaking.

For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after sexual intercourse.

Using a nozzle, insert the contents of the bottle into the urethra of men (2-3 ml), women (1-2 ml) and into the vagina (5-10 ml) for 2-3 minutes. Treat the skin of the inner thighs, pubis, and genitals. After the procedure, do not urinate for 2 hours.

Complex treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml of a 0.05% solution of chlorhexidine bigluconate into the urethra 1-2 times a day, the course is 10 days, procedures are prescribed every other day. Intravaginally, 1 suppository 3-4 times a day for 7-20 days, depending on the nature of the disease.

A rinse solution and a topical gel are usually prescribed 2-3 times a day. Plaster: remove the protective film from the surface of the plaster without touching the bandage pad with your fingers, and apply it to the damaged area of ​​the skin. Press the edges of the patch with your fingers so that the sticky part of the patch fixes the bandage.

Features of the areas of application of Miramistin and Chlorhexidine, the question of price

Based on all of the above, we can conclude that Miramistin and Chlorgekidine are not always interchangeable. There are diseases for which only Miramistin is really applicable. There are also areas for which only Miramistin can be treated, or it is safer to use it.

But on the other hand, there are areas of application in which all the advantages of Miramistin are redundant, and the price is unreasonably high. For example, using Miramistin for sterile cleaning of the house or for daily treatment of hands, shoes and clothes will be too expensive, despite the fact that cheap Chlorhexidine will cope with this task no worse.

It makes no sense to name specific prices, since they change often, but to get an idea of ​​the difference in price, it is worth pointing out that the price of Miramistin is at least 10 times more, and in some pharmacies the difference can reach 20 times. Here you will find the price of Miramistin spray.

Therefore, before choosing a drug, you first need to focus on the purpose for which it will be used. In all cases of doubt, trust specialists.

If there is no confidence in the professional suitability of a specialist or there is no way to contact him, then for complete confidence in safety it is better to use Miramistin.

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