Coldrex medicine

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Coldrex - instructions for use, reviews, analogs and release forms (powder for preparing HotRem solution, Knight and Broncho syrup, MaxGrip, Junior HotDrink, tablets) medications for the treatment of colds in adults, children and pregnancy.

Table of contents:

Compound

In this article you can read the instructions for using the drug Coldrex. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Coldrex in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Coldrex in the presence of existing structural analogues. Use to treat cold and flu symptoms in adults, children, and during pregnancy and breastfeeding. Composition and interaction of the drug with alcohol.

Coldrex is a combination drug for the symptomatic treatment of acute respiratory diseases.

Paracetamol has antipyretic and analgesic effects. Eliminates fever, reduces headaches, muscle and joint pain that often accompany the flu.

Phenylephrine hydrochloride is a sympathomimetic, it constricts the vessels of the nasal mucosa and paranasal sinuses, resulting in reduced swelling and easier nasal breathing.

Ascorbic acid replenishes the increased need for vitamin C during colds and flu, especially in the initial stages of the disease.

The active components of the drug do not cause drowsiness and do not impair concentration.

Promethazine is a histamine H1 receptor blocker. Eliminates swelling of the nasal mucosa and upper respiratory tract, restoring nasal breathing and reducing the amount of nasal discharge.

Dextromethorphan is an antitussive drug that inhibits the excitability of the cough center and suppresses cough of any origin.

Coldrex Broncho - reduces the surface tension and adhesive properties of sputum, which reduces its viscosity and facilitates removal from the respiratory tract. The use of the drug contributes to the transition of a non-productive cough to a productive one.

Paracetamol + Caffeine + Phenylephrine hydrochloride + Terpinhydrate + Ascorbic acid (vitamin C) + excipients (Coldrex).

Paracetamol + Phenylephrine hydrochloride + Ascorbic acid + excipients (HotRem, MaxGrip and Junior HotDrink).

Paracetamol + Promethazine hydrochloride + Dextromethorphan hydrobromide + excipients (Knight).

Guaifenesin + excipients (Broncho syrup).

Paracetamol is quickly and almost completely absorbed from the gastrointestinal tract, distribution in body fluids is relatively even. Metabolized primarily in the liver with the formation of several metabolites. The main amount of the drug is excreted after conjugation in the liver. No more than 3% of the received dose of paracetamol is excreted unchanged.

Ascorbic acid is well absorbed from the gastrointestinal tract. Distribution in body tissues is wide. Metabolized in the liver, excreted in the urine in the form of oxalate and unchanged. Ascorbic acid, taken in excessive quantities, is quickly excreted unchanged in the urine.

Phenylephrine is poorly absorbed from the gastrointestinal tract and undergoes first-pass metabolism in the intestine and liver under the influence of MAO. When phenylephrine is taken orally, the bioavailability of the drug is limited. It is excreted almost entirely in the urine as a sulfuric acid conjugate.

Relieving cold and flu symptoms:

  • increased body temperature;
  • headache;
  • chills;
  • pain in joints and muscles,
  • nasal congestion;
  • dry cough;
  • acute tracheitis;
  • bronchitis of various etiologies;
  • sore throat;
  • pain in the sinuses.

Powder for the preparation of a solution for oral administration (for children) (Junior HotDrink).

Powder for the preparation of a solution for oral administration (HotRem and MaxGrip).

Syrup (Broncho and Knight).

Instructions for use and dosage regimen

Adults and children over 12 years of age are prescribed 2 tablets up to 4 times a day. Children aged 6-12 years - 1 tablet up to 4 times a day.

Do not exceed the recommended dose. It is not recommended to use the drug for more than 5 days without consulting a doctor. If symptoms persist, you should consult a doctor.

Powder Junior HotDrink

Children aged 6 to 12 years are prescribed 1 sachet every 4 hours. Do not use more than 4 sachets in 24 hours. Do not exceed the indicated dose. The maximum duration of use is no more than 5 days. If symptoms persist, consult a doctor. The doctor determines the need to continue treatment individually.

Pour the contents of 1 sachet into a mug, pour in about 125 ml of hot water, stir until dissolved. If necessary, add cold water and sugar.

Powder HotRem and MaxGrip

Adults are recommended to take 1 sachet every 4-6 hours, but no more than 4 sachets within 24 hours. The interval between doses should be at least 4 hours.

Children over 12 years of age are prescribed 1 sachet every 6 hours, but not more than 3 sachets in 24 hours.

The contents of 1 sachet must be poured into a glass of hot water (200 ml), stir until completely dissolved, if necessary, you can add cold water or sugar.

The maximum duration of use of the drug is 5 days.

For adults (including elderly patients) and children over 12 years of age, the drug is prescribed in a single dose of 200 mg (10 ml). Fill the supplied measuring cup with syrup to the 10 ml mark and drink the drug. If necessary, a single dose can be taken again every 2-3 hours.

For children aged 3 to 12 years, the drug is prescribed in a single dose of 100 mg (5 ml). Fill the supplied measuring cup with syrup to the 5 ml mark and drink the drug. If necessary, a single dose can be taken again every 2-3 hours.

The drug is taken only once a day, at night, just before bedtime.

For adults (including elderly patients) and children over 12 years of age, the drug is prescribed in a single dose of 20 ml (4 spoons of 5 ml).

For children aged 6 to 12 years, the drug is prescribed in a single dose of 10 ml (2 spoons of 5 ml).

  • allergic reactions (skin rash, urticaria, angioedema);
  • thrombocytopenia, leukopenia, agranulocytosis;
  • irritation of the gastrointestinal mucosa;
  • dry mouth;
  • nausea, vomiting;
  • diarrhea;
  • headache;
  • dizziness;
  • bronchial obstruction;
  • insomnia;
  • slight increase in blood pressure;
  • heartbeat.
  • genetic absence of glucose-6-phosphate dehydrogenase;
  • diseases of the blood system;
  • liver diseases;
  • kidney diseases;
  • thyrotoxicosis;
  • diabetes;
  • arterial hypertension;
  • heart disease (severe stenosis of the aortic mouth, acute myocardial infarction, tachyarrhythmias);
  • benign prostatic hyperplasia;
  • angle-closure glaucoma;
  • simultaneous use with other paracetamol-containing drugs;
  • simultaneous use of antidepressants, including MAO inhibitors, and a period of up to 14 days after their discontinuation;
  • epilepsy;
  • pregnancy;
  • lactation (breastfeeding);
  • children's age up to 18 years (MaxGrip), up to 12 years (HotRem), up to 6 years (Knight and Junior HotDrink), up to 3 years (Broncho);
  • hypersensitivity to the ingredients included in the drug.

Use during pregnancy and breastfeeding

Coldrex is contraindicated for use during pregnancy.

If it is necessary to use it during lactation, the issue of stopping breastfeeding should be decided.

The patient should be informed that if symptoms of the disease persist after 5 days of using the drug, they should stop taking it and consult a doctor.

The drug should be taken only in recommended doses.

The drug should not be taken simultaneously with other drugs containing paracetamol, as well as other non-narcotic analgesics (metamizole sodium), non-steroidal anti-inflammatory drugs (NSAIDs) (acetylsalicylic acid, ibuprofen), barbiturates, anticonvulsants, rifampicin and chloramphenicol.

Coldrex should be taken with caution simultaneously with metoclopramide, domperidone, cholestyramine, and indirect anticoagulants (warfarin).

Patients taking Coldrex should avoid drinking alcohol. It is not recommended to prescribe the drug for chronic alcoholism.

Patients on a low-sodium diet should be aware that 1 sachet of Coldrex contains 0.12 g of sodium.

When conducting tests to determine the level of uric acid and blood glucose levels, you should warn your doctor about the use of the drug Coldrex, since the drug may distort the results of laboratory tests assessing the concentration of glucose and uric acid.

Paracetamol, when taken for a long time, enhances the effect of indirect anticoagulants (warfarin and other coumarins), which increases the risk of bleeding.

Inducers of microsomal oxidation enzymes in the liver (barbiturates, diphenin, carbamazepine, rifampicin, zidovudine, phenytoin, ethanol (alcohol), flumecinol, phenylbutazone and tricyclic antidepressants) increase the risk of hepatotoxicity in overdoses and concomitant use with paracetamol.

Microsomal oxidation inhibitors (cimetidine) reduce the risk of hepatotoxicity.

Paracetamol reduces the effectiveness of diuretics.

Metoclopramide and domperidone increase, and cholestyramine reduces the rate of absorption of paracetamol.

Paracetamol enhances the effects of MAO inhibitors, sedatives, ethanol (alcohol).

Kodrex when taken with MAO inhibitors can lead to an increase in blood pressure.

Phenylephrine reduces the effectiveness of beta-blockers and antihypertensive drugs.

Tricyclic antidepressants enhance the sympathomimetic effect of phenylephrine; simultaneous administration of halothane with phenylephrine increases the risk of developing ventricular arrhythmia.

Phenylephrine reduces the hypotensive effect of guanethidine, which, in turn, enhances the alpha-adrenergic stimulating activity of phenylephrine.

Antidepressants, antiparkinsonian drugs, antipsychotic drugs, phenothiazine derivatives increase the risk of developing urinary retention, dry mouth, and constipation.

The simultaneous administration of glucocorticosteroids (GCS) with phenylephrine increases the risk of developing glaucoma.

Analogues of the drug Coldrex

Structural analogues of the active substance:

Analogs by pharmacological group (anilides in combinations):

  • Adjikold;
  • AnGriCaps maxima;
  • Antigrippin;
  • AntiFlu;
  • AntiFlu Kids;
  • Apap S Plus;
  • Brustan;
  • Vicks Active SymptoMax;
  • Gevadal;
  • Influenza;
  • Grippostad;
  • Grippostad Good Knight;
  • Grippostad S;
  • GrippoFlu for colds and flu;
  • Grippoflu extra for colds and flu;
  • Gripend;
  • Gripend HotActive;
  • Gripend HotActive Max;
  • Daleron C;
  • Daleron C junior;
  • Children's Tylenol for colds;
  • Dolaren;
  • Ibuklin;
  • Influblock;
  • Influnet;
  • Caffetin;
  • Caffetin Cold;
  • Codelmixt;
  • Coldact Flu Plus;
  • Coldrex MaxGrip;
  • Coldrex Knight;
  • Coldrex Hotrem;
  • Coldrex Hotrem with lemon flavor;
  • Coldrex Hotrem with lemon and honey flavor;
  • Coldrex Junior Hot Drink;
  • Coldfree;
  • Coffedon;
  • Lemsip Lemon;
  • Lemsip Max;
  • Lemsip Blackcurrant;
  • Maxicold;
  • Maxicold Rhino;
  • Meksavit;
  • Migraine;
  • Migrenol;
  • Mulsinex;
  • Next;
  • Neoflu 750;
  • Novalgin;
  • Padevix;
  • Panadeine;
  • Panadol Extra;
  • Panoxen;
  • Paracodamol;
  • Paralen extra;
  • Paracetamol Extra;
  • Paracetamol Extra for children;
  • Pentalgin;
  • Pentaflucin;
  • Plivalgin;
  • Cold;
  • Prohodol forte;
  • Rinza;
  • Rinzasip;
  • Rinicold;
  • Saridon;
  • Solpadeine;
  • Solpadeine Fast;
  • Stopgripan;
  • Stopgripan forte;
  • Strimol plus;
  • Tylenol for colds;
  • TeraFlu;
  • TheraFlu for flu and colds;
  • TheraFlu for flu and colds Extra;
  • TheraFlu Extratab;
  • Toff plus;
  • Trigan D;
  • Fastorik;
  • Fastorik plus;
  • Febricet;
  • Femizol;
  • Fervex;
  • Fervex for children;
  • Fervex for dry cough;
  • Fervex rhinitis;
  • Flucoldin;
  • Flucoldex;
  • Flucomp;
  • Flucomp Extratab;
  • Flustop;
  • Khairumat;
  • Efferalgan with vitamin C;
  • Unispaz.

Source: http://instrukciya-otzyvy.ru/510-koldreks-po-primeneniyu-analogi-poroshok-rastvor-hotrem-sirop-nayt-bronho-maksgripp-yunior.html

Coldrex

Instructions for use:

Price in online pharmacies:

Coldrex is a combination drug that is used to treat influenza and acute respiratory infections. This drug is available in the form of tablets, syrup and powder for the preparation of a solution for oral administration.

Composition and release form

The composition of one Coldrex tablet includes: paracetamol - 0.5 g, ascorbic acid - 0.03 g, terpin hydrate 0.02 g, phenylephrine hydrochloride - 5 mg and caffeine 0.025 g.

Coldrex Hotrem is a powder for preparing an oral solution that is yellow in color and has a characteristic lemon odor. Dissolving in hot water, the drug turns into a pale yellow solution with a pronounced lemon smell.

One sachet contains: paracetamol 750 mg, phenylephrine hydrochloride 10 mg, ascorbic acid 60 mg.

Available in 5 g sachets with the scent of lemon and black currant.

Coldrex Night is a dark green syrup, transparent, viscous and has a medicinal mint smell.

The syrup contains: paracetamol 1 g, dextromethorphan hydrobromide 15 mg, promethazine hydrochloride 20 mg.

Coldrex Knight is available in 20 ml bottles.

pharmachologic effect

The drug Coldrex can quickly relieve all the symptoms of the disease, such as a sore throat, a feeling of nasal congestion, fever and muscle pain, as it has an anti-inflammatory, antipyretic, and analgesic effect.

Paracetamol is the active drug substance of Coldrex. It has anti-inflammatory, antipyretic, and analgesic effects for colds. Penetrating into the body, paracetamol slows down the metabolism of arachidonic acid and reduces the synthesis of prostaglandins, prostacyclins and thromboxane in the tissues of the central nervous system. It is also able to influence thermoregulation in the hypothalamus, which leads to a decrease in elevated temperature.

Phenylephrine hydrochloride is a drug that helps to constrict blood vessels located in the nasal mucosa and paranasal sinuses. This remedy actively eliminates swelling of the nasal mucosa, reduces the level of rhinorrhea and facilitates nasal breathing.

Ascorbic acid or vitamin C is also included in the Coldrex drug and has a strong immunostimulating and antioxidant effect. Vitamin C also protects the cells and tissues of the body from the negative effects of free radicals and peroxide compounds.

After using Coldrex, all active components easily dissolve in the gastrointestinal tract and are excreted in the urine. The concentration of paracetamol in the blood plasma is observed minutes after taking the drug.

Indications

It is recommended to use the above Coldrex group drugs for symptoms of colds and flu, such as fever, nasal congestion, muscle pain, headache, chills, runny nose, sore throat.

Use during pregnancy and breastfeeding

You should be especially careful when using Coldrex during pregnancy and breastfeeding.

Contraindications

The instructions for Coldrex contraindicate taking the drug for the following diseases:

  • severe kidney and liver disorders;
  • diabetes;
  • heart disease;
  • prostate adenoma;
  • diseases of the blood system;
  • arterial hypertension;
  • closed glaucoma;
  • thyrotoxicosis.

The use of Coldrex is also contraindicated in cases of hypersensitivity, in children under 6 years of age, and when taking the drug simultaneously with other medications containing paracetamol. It is not recommended to take the drug for people suffering from epilepsy and people who have taken antidepressants for two weeks.

Instructions for use (method and dosage)

The instructions for Coldrex recommend taking the drug in different forms as follows:

Adults and children over 12 years of age should take Coldrex tablets 4 times a day, 2 pieces. Children from 6 to 12 years old need to take 1 tablet 4 times a day.

Coldrex Knight (syrup) should be taken at night before bed. Children over 12 years old and adults: 20 ml measuring cup. Children from 6 to 12 years old: 10 ml measuring cup. In case of an overdose of paracetamol above 4 g, Coldrex Night should be discontinued.

The contents of the Coldrex Hotrem sachet are dissolved in hot water. The recommended daily dose for adults is no more than 4 sachets. The break between doses should be hours. For children over 12 years old, Coldrex Hotrem is prescribed 3 sachets per day every 6 hours. The duration of treatment is no longer than 3 days.

According to the instructions, the use of Coldrex for more than five days without consulting a doctor is prohibited.

Side effects

In case of an overdose of Coldrex tablets, as well as another type of drug, side effects are possible such as:

  • nausea, vomiting, diarrhea;
  • increased blood pressure;
  • heart rhythm disturbances, anemia, thrombocytopenia, neutropenia, agranulocytosis;
  • headache, tinnitus, dizziness, increased irritability;
  • renal colic, decreased amount of urine excreted;
  • skin rashes, increased sweating;
  • increase in blood glucose.

Storage conditions and shelf life

Coldrex should be stored in a dry and dark place at a temperature not exceeding 25C. The shelf life of Coldrex tablets is 4 years, Coldrex Knight - 3 years, Coldrex Hotrem - 2 years.

The description posted on this page is a simplified version of the official version of the annotation for the drug. The information is provided for informational purposes only and does not constitute a guide for self-medication. Before using the medicine, you must consult a specialist and read the instructions approved by the manufacturer.

Coldrex Hotrem powder 5 g with lemon flavor 5 pcs.

Coldrex Hotrem powder 5 g honey and lemon 5 pcs.

Coldrex hotrem lemon No. 5 por.

Coldrex hotrem honey-lemon No. 5 por.

Coldrex MaxGripp powder 6.427 g lemon 5 pcs.

When using materials from the site, the active reference is obligatory.

The information presented on our website should not be used for self-diagnosis and treatment and cannot serve as a substitute for consultation with a doctor. We warn you about the presence of contraindications. Specialist consultation is required.

Source: http://dolgojit.net/koldreks.php

Coldrex

Coldrex: instructions for use and reviews

Latin name: Coldrex

ATX code: N02BE51

Active ingredient: caffeine + paracetamol + ascorbic acid + terpinihydrate + phenylephrinum (coffeinum + paracetamolum + acidum ascorbinicum + therpini hydras + phenylephrinum)

Manufacturer: GlaxoSmithKline Dungarvan, Ltd., Ireland

Update of description and photo: 07/31/2017

Prices in pharmacies: from 151 rub.

Coldrex is a drug with decongestant, expectorant, analgesic and antipyretic effects, used for the symptomatic treatment of influenza and colds.

Release form and composition

Coldrex is produced in the form of tablets: capsule-shaped, two-layer, orange-white, the orange layer may contain white inclusions, with “Coldrex” embossed on one side (5, 6, 8, 12 pieces in blisters, 1 or 2 blisters in a cardboard box).

1 tablet contains the following active ingredients:

  • Caffeine – 25 mg;
  • Paracetamol – 500 mg;
  • Terpinhydrate – 20 mg;
  • Phenylephrine hydrochloride – 5 mg;
  • Vitamin C (ascorbic acid) – 30 mg.

Auxiliary components in Coldrex: talc, soluble and corn starch, dye, povidone, potassium sorbate, stearic acid, sodium lauryl sulfate.

Pharmacological properties

Pharmacodynamics

Coldrex is a combination drug, the components of which have the following effects on the body:

  • paracetamol is an analgesic that inhibits the synthesis of prostaglandins in the central nervous system and affects the thermoregulation center located in the hypothalamus;
  • phenylephrine is a sympathomimetic that eliminates swelling of the nasal mucosa and facilitates breathing;
  • ascorbic acid compensates for vitamin C deficiency, which causes the development of viral infections, and also strengthens the immune system and normalizes capillary permeability;
  • caffeine, which belongs to the group of methylxanthines, intensively stimulates the activity of the central nervous system, increases diuresis, promotes dilation of the lumen of blood vessels, enhances the analgesic effect of paracetamol, stimulates the secretory function of the stomach, reduces platelet aggregation;
  • Terpin hydrate is an expectorant and enhances bronchial secretions.

Pharmacokinetics

Paracetamol is almost completely absorbed from the gastrointestinal tract. It undergoes biotransformation in the liver and is excreted in the urine.

Ascorbic acid is absorbed from the gastrointestinal tract at high speed and transported to all tissues of the body. The degree of its binding to plasma proteins is about 25%. The remaining amount of ascorbic acid is excreted in the urine.

Caffeine is absorbed very easily after oral administration. The maximum content of the substance in plasma is recorded 1 hour after entering the body. The half-life is approximately 3.5 hours.

Phenylephrine is absorbed unevenly from the gastrointestinal tract. When taken orally, its bioavailability decreases significantly. Almost 100% of the administered dose of phenylephrine is excreted in the urine.

Indications for use

According to the instructions, Coldrex is prescribed to eliminate symptoms of flu and colds, such as:

  • Headache;
  • Fever;
  • Chills;
  • Feeling of nasal congestion;
  • Sore throat and sinuses;
  • Muscle and joint pain.

Contraindications

  • Diseases of the circulatory system;
  • Arterial hypertension;
  • Severe functional disorders of the kidneys or liver;
  • Diabetes;
  • Thyrotoxicosis;
  • Genetic absence of glucose-6-phosphate dehydrogenase;
  • Simultaneous use with other drugs containing paracetamol;
  • Hypersensitivity to the components of the drug.

Nursing and pregnant women, as well as children under 6 years of age, can take Coldrex only after medical consultation.

Instructions for use of Coldrex: method and dosage

Coldrex tablets are taken orally.

The dosage regimen is determined by age:

  • Adults and children over 12 years old – 2 tablets;
  • Children 6-12 years old – 1 tablet.

Frequency of administration – up to 4 times a day.

The recommended dose should not be exceeded.

It is not recommended to take Coldrex for longer than 5 days without consulting a doctor. If symptoms persist, you should consult a doctor.

Side effects

When used in recommended doses, the drug is generally well tolerated.

Possible side effects that occur during administration are determined by the components included in Coldrex.

Paracetamol may cause the following disorders:

  • Sometimes: allergic reactions (angioedema, urticaria, skin rash);
  • Rarely: blood picture disturbances.

With prolonged use of doses exceeding the recommended ones, hepatotoxic and nephrotoxic effects may develop.

The use of phenylephrine can lead to disorders of certain body systems:

  • Digestive system: nausea;
  • Cardiovascular system: headache, slight increase in blood pressure; rarely – palpitations (symptoms disappear after discontinuation of the drug).

Overdose

In case of an overdose of Coldrex, it is recommended to immediately consult a doctor, even if the patient feels well. Its symptoms include cardiac arrhythmias, pain in the stomach, nausea, vomiting, pale skin, and excessive sweating. 1-2 days after taking high doses of the drug, signs of liver damage are often observed. In complicated cases, acute liver failure and coma may develop.

It is recommended to perform gastric lavage within the first 4 hours after taking Coldrex and then undergo symptomatic treatment. For paracetamol intoxication, acetylcysteine ​​is a specific antidote.

special instructions

Excessive consumption of coffee or tea during therapy can lead to the development of irritability and nervous tension.

To avoid toxic liver damage, patients should refrain from drinking alcohol. For chronic alcoholism, taking Coldrex tablets is not recommended.

Impact on the ability to drive vehicles and complex mechanisms

If dizziness occurs while taking the drug, it is necessary to avoid engaging in potentially hazardous activities that require increased concentration and immediate psychomotor reactions (driving a car and other vehicles, working with complex moving mechanisms, etc.).

Drug interactions

When Coldrex is used simultaneously with certain medications, undesirable effects may occur:

  • Diphenin, barbiturates, rifampicin, carbamazepine, zidovudine and other inducers of microsomal liver enzymes: increased risk of hepatotoxicity;
  • Domperidone, metoclopramide: increase the rate of absorption of paracetamol;
  • Cholestyramine: decreased rate of absorption of paracetamol.

The simultaneous use of Coldrex with beta-blockers, tricyclic antidepressants and monoamine oxidase inhibitors is not recommended. Between doses of drugs, a break of at least 14 days should be observed.

Analogs

An analogue of Coldrex is Flucoldex forte.

Terms and conditions of storage

Store in a dry place, out of reach of children.

Shelf life – 4 years.

Conditions for dispensing from pharmacies

Available without a prescription.

Reviews of Coldrex

Almost all reviews about Coldrex are positive. Patients who have taken the drug note its effectiveness. Coldrex eliminates almost all cold symptoms in record time. Patients report the disappearance of chills, a decrease in temperature and the disappearance of sore throat.

Price for Coldrex in pharmacies

The price of Coldrex in pharmacies varies from approximately 140 to 186 rubles (the package includes 12 pieces).

Coldrex Hotrem powder 5 g with lemon flavor 5 pcs.

Coldrex Hotrem powder 5 g honey and lemon 5 pcs.

Coldrex hotrem lemon No. 5 por.

Coldrex MaxGripp powder 6.427 g lemon 5 pcs.

Coldrex hotrem honey-lemon No. 5 por.

Coldrex maxgrip lemon No. 5 por.

Coldrex hotrem honey/lemon powder n5

Education: First Moscow State Medical University named after I.M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Source: http://www.neboleem.net/koldreks.php

Coldrex - instructions for use

Coldrex is a combination drug with antipyretic and analgesic properties that helps cope with the symptoms of colds and flu. According to the instructions, the drug helps reduce swelling of the mucous membrane and constriction of blood vessels in the nose, thereby facilitating nasal breathing and eliminating lacrimation. In fact, they can replace most cold remedies. In pharmacies, Coldrex is presented in three dosage forms, and we will talk about each of them in more detail.

Release forms

Coldrex is a whole group of drugs that is used to relieve symptoms of flu and colds. The medicine is available in three forms.

They contain the largest amount of active ingredients, which helps to quickly get rid of the symptoms of ARVI. Coldrex tablets are indicated for use in adults and children aged 6-7 years;

The medicine in powder form is quickly absorbed into the blood, due to which it begins to act within 15 minutes after use.

  • Coldrex Max Flu is a medicine for adults, which contains a maximum dose of paracetamol;
  • Coldrex Hotrem is a powder with flavorings that give the drink a taste of honey or lemon. It contains saccharin and sucrose, so it is not recommended for diabetics;
  • Coldrex Junior - designed specifically for children. The suspension contains fewer active ingredients, which reduces the likelihood of side effects.

The powder is diluted with water and then taken orally. In addition to active substances, the drug contains flavorings that give the hot drink a pleasant lemon or honey-lemon flavor.

The release form is represented by two types of the drug - Coldrex Broncho and Coldrex Knight. These are expectorants and antipyretics, which include guaifenesin and camphor. According to the instructions, the syrup can be given not only to adults, but also to children over 3 years old.

Compound

Coldrex is a symptomatic drug, that is, it relieves cold symptoms, but does not fight the causes of their occurrence.

Coldrex, regardless of its release form, contains three main active ingredients:

  • Paracetamol is an effective antipyretic with an analgesic effect. A non-narcotic analgesic reduces the number of prostaglandins in the body, and also helps to normalize the functioning of the thermoregulation center in the hypothalamus.
  • Ascorbic acid is an immunostimulating vitamin that helps increase nonspecific immunity. Thanks to vitamin C, Coldrex stimulates an increase in the phagocytic activity of macrophages. Moreover, ascorbic acid gives the drug antioxidant properties.
  • Phenylephrine is a symptomatic remedy that eliminates swelling of the mucous membrane of the ENT organs. Helps cope with rhinorrhea and nasal congestion.

Thanks to this composition, the drug relieves almost all symptoms of a cold in the shortest possible time. However, it does not cause drowsiness or an allergic reaction.

Indications for use

The drug will help get rid of the following symptoms:

  • hyperthermia (increased temperature);
  • nasal congestion and rhinitis;
  • muscle pain and chills;
  • discomfort in the throat and paranasal sinuses;
  • headaches and lacrimation.

In other words, Coldrex relieves unpleasant symptoms in the following diseases:

Reception scheme

Powders HotRem and MaxGrip

Pour the contents of 1 sachet into a glass of hot water (200 ml) and stir until completely dissolved. You can add cold water or sugar before use.

  • for adults - 1 sachet 3-4 times a day with an interval of 4-6 hours, but no more than 4 sachets within 24 hours;
  • for children over 12 years old - 1 sachet every 6 hours, but not more than 3 sachets within 24 hours.

Children from 6 to 12 years old are recommended to take 1 sachet every 4 hours, but no more than 4 sachets per day. Do not exceed the indicated dose.

The contents of the sachet are poured into a mug and 125 ml of hot water is poured in, then stirred until completely dissolved.

The drug is taken regardless of meals, washed down with plenty of water.

  • for children 6-12 years old – 1 tablet 3-4 times a day;
  • for children over 12 years old – 2 tablets no more than 4 times a day;
  • for adults – 2 tablets up to 5 times a day.

Despite the high concentration of active substances in the tablets, they can be used even by pregnant women, but only after consultation with a specialist.

For convenience, each package of the drug is equipped with a measuring cup with marks of 5 and 10 ml.

  • adults and children over 12 years of age mg (10 ml) per dose;
  • children aged 3 to 12 years mg (5 ml) per 1 dose.

In both cases, if necessary, a single dose can be taken again every 2-3 hours.

The drug is taken 1 time per day - at night just before bedtime.

  • adults and children over 12 years old - 20 ml (4 spoons of 5 ml);
  • children aged 6 to 12 years - 10 ml (2 spoons of 5 ml).

Regardless of the form of release, Coldrex should not be used for more than 5 days in a row. If symptoms persist, you should interrupt treatment and consult a doctor.

Contraindications for use

Coldrex contains paracetamol, which in large quantities can create a load on some internal organs, in particular the liver and kidneys. Therefore, it is undesirable to use it if you have:

  • diabetes mellitus and hypertension;
  • heart disease and hyperthyroidism;
  • kidney and liver dysfunction;
  • disturbances in the hematopoietic process.

In addition, it is prohibited to combine Coldrex with other medications that contain paracetamol.

Side effects

If the dosage is observed, Coldrex is well tolerated by most patients. In rare cases, the following adverse reactions may occur:

  • headache;
  • nausea;
  • increased heart rate;
  • increased blood pressure;
  • allergic reactions in the form of rash, urticaria, angioedema.

As already noted, paracetamol creates a considerable load on the “filtration” system, which includes the liver and kidneys. When interacting with alcohol, paracetamol leads to severe intoxication of the body, which is accompanied by the following side effects:

  • nausea and dizziness;
  • rapid heartbeat and vomiting;
  • bronchial obstruction and diarrhea;
  • dry mouth and headaches.

Source: http://prostudynet.ru/lechenie/preparaty/koldreks-poroshok

Coldrex - tablets, capsules, powder and syrup for oral administration for flu and colds. Detailed description of the drug.

Nobody likes to be sick. During a cold, everyone is looking for an effective remedy that will relieve the ailment as quickly as possible. Often their choice is left to Coldrex drugs. Any type of antibiotic is prescribed by a doctor for more severe diseases and has many contraindications.

Before you continue reading: If you are looking for an effective method of getting rid of a runny nose, pharyngitis, tonsillitis, bronchitis or colds, then be sure to look at this section of the site after reading this article. This information has helped so many people, we hope it will help you too! So, now back to the article.

You can choose the Coldrex drug that is most suitable for your case. The use of this drug during colds has proven its effectiveness in both adults and children. The instructions for Coldrex preparations are clear, which does not complicate their use.

Coldrex is chosen when you need to find a quick and safe remedy to fight colds.

  • pills;
  • powder with different flavors;
  • syrup;
  • extended-release capsules.

Next, we will consider the instructions for use of all dosage forms of the drug Coldrex. Let's find out whether the drug can be used during pregnancy, as well as the possibility of taking it while breastfeeding. Let's consider and compare the analogues of Coldrex - Theraflu and Fervex.

Coldrex tablets

Previously, Coldrex preparations were produced in powder form, which made them difficult to use on the road, at work and in other places where it is not possible to use the powder to prepare a hot drink. Now a form has appeared - in tablets.

Indications for use are symptoms of a cold: fever, headaches, nasal congestion or excessive discharge, chills, discomfort in the nasopharynx and pain in muscles and joints.

Each tablet contains:

  • paracetamol, which has an antipyretic and analgesic effect;
  • caffeine, which has a tonic effect;
  • phenylephrine, which relieves swelling of the mucous membranes in the nose and sinuses;
  • vitamin C (ascorbic acid), which supplements the body's need for this vitamin during colds.

The tablets also contain other substances, but they are auxiliary (soluble starch, corn starch, talc and others).

Capsule-shaped tablets, two-layer (white and orange). One side of the tablets is embossed (Coldrex).

  • special sensitivity to the components of Coldrex tablets;
  • blood diseases;
  • any disturbances in the normal functions of the liver or kidneys;
  • diabetes;
  • thyrotoxicosis;
  • arterial hypertension;
  • taking other medications that contain paracetamol.

Coldrex is recommended for adults and children over 12 years old, two tablets no more than four times a day, and for children over six years old, one tablet.

You should not take Coldrex for more than five days without consulting your doctor. If symptoms persist, the specialist will prescribe another drug treatment.

If you take Coldrex tablets according to the instructions in the indicated doses, the drug should be tolerated quite well.

Paracetamol has side effects quite rarely. The only possible manifestation of any allergic reactions (skin rash, itching, urticaria). With long-term use of an increased dose of paracetamol, toxic effects on the kidneys and liver may occur.

Phenylephrine sometimes causes nausea, headaches, increased heart rate, and a slight increase in blood pressure.

Caffeine when combined with excessive consumption of coffee or tea can produce reactions in the form of irritability and nervous excitability.

If any reactions occur while taking Coldrex tablets, you should consult a doctor.

The first signs of an overdose of Coldrex are deterioration in health, accompanied by nausea, vomiting, stomach pain and increased sweating. After some time, signs of liver toxicity may also appear. Other more severe cases of poisoning are accompanied by coma and liver failure.

At the first signs of a drug overdose, it is recommended to induce vomiting and consult a doctor. The patient needs to undergo gastric lavage in the next four hours, then treatment as indicated.

Interaction of Coldrex components with other drugs:

Coldrex is not used simultaneously and within two weeks after their discontinuation:

  • with beta-blockers;
  • with tricyclic antidepressants;
  • with MAO inhibitors.

Possible development of toxic liver damage:

  • with barbiturates;
  • with diphenine;
  • rifampicin and other liver enzyme inducers.

To take the drug Coldrex, you must consult with your doctor when using:

  • metoclopramide and domperidone, which are used to treat nausea and vomiting (both drugs speed up the absorption of paracetamol);
  • cholestyramine, which is used to lower cholesterol (slows down the absorption of paracetamol).
  • Coldrex should not be combined with alcohol consumption;
  • This drug can be taken for children from the age of six. For use by children under this age, a doctor’s recommendation is required;
  • Pregnant women can take it, but only after consulting a specialist;
  • the same applies to use in nursing mothers.

Coldrex tablets are available from pharmacies without a prescription.

Storage conditions: in a dry place, out of reach of children, at a temperature of no more than 25 C.

Shelf life: 4 years.

Coldrex hotrem

Coldrex Hotrem is a powder that is soluble in water. The result is a solution with a lemon or blackcurrant taste.

The powder contains paracetamol, phenylephrine and ascorbic acid (vitamin C). Excipients: flavorings that give the solution a characteristic smell (lemon, raspberry or blackcurrant), citric acid, sucrose, sodium saccharin and others.

Indications for use are symptoms of a cold: fever, headaches, nasal congestion or excessive discharge, chills, discomfort in the nasopharynx and pain in muscles and joints.

  • special sensitivity to the components of Coldrex Hotrem;
  • blood diseases;
  • any disturbances in the normal functions of the liver or kidneys;
  • diabetes;
  • thyrotoxicosis;
  • arterial hypertension;
  • taking other medications that contain paracetamol.

Pour the powder from the bag into a container, add 200 ml of hot water and stir. You can add sugar and cold water.

Coldrex Hotrem can only be taken by children over 12 years of age.

Dosage: adults – one sachet every 4-6 hours, but not more than four sachets per day;

children - one Coldrex sachet every six hours, but no more than three sachets per day.

Without consulting your doctor, according to the instructions, it is not recommended to take Coldrex Hotrem for more than five days. If symptoms persist, the specialist will prescribe another drug treatment.

If you take Coldrex Hotrem according to the instructions in the indicated doses, the drug should be tolerated quite well.

Paracetamol has side effects quite rarely. The only possible manifestation of any allergic reactions (skin rash, itching, urticaria). With long-term use of an increased dose of paracetamol, toxic effects on the kidneys and liver may occur.

Phenylephrine sometimes causes nausea, headaches, increased heart rate, and a slight increase in blood pressure.

If you experience any reactions while using Coldrex Hotrem, you should consult a doctor.

The first signs of an overdose of Coldrex Hotrem are deterioration in health, accompanied by nausea, vomiting, stomach pain and increased sweating. After some time, signs of liver toxicity may also appear. Other more severe cases of poisoning are accompanied by coma and liver failure.

At the first signs of an overdose of Coldrex Hotrem, it is recommended to induce vomiting and consult a doctor. The patient must undergo gastric lavage during the first four hours, then treatment as indicated.

The interaction with other medications is similar to that of Coldrex tablets.

Special instructions when taking the drug:

This dosage form of the drug is not prohibited during pregnancy. But the drug should be taken only on the recommendation of the attending physician. The same applies when breastfeeding.

There are no contraindications when working with machinery or driving a vehicle, since it does not have a sedative effect.

The remaining instructions are the same as for Coldrex tablets.

Dispensed from pharmacies without a prescription.

Storage conditions: in a dry place, out of reach of children, at a temperature of no more than 25 C.

Shelf life: 3 years.

Coldrex maxgripp

Coldrex maxgripp contains paracetam in the maximum permitted single dose – 1000 mg. This is one of the few drugs containing such a dose of paracetamol, the sale of which is allowed from pharmacies without a prescription.

Coldrexa maxgripp is intended for people who want to get rid of cold symptoms very quickly.

Ingredients: paracetamol, phenylephrine and ascorbic acid (vitamin C). Excipients: flavoring, which gives the solution a characteristic lemon smell, citric acid, sodium saccharin, sugar, sodium citrate and others.

Contraindications for the use of Coldrex maxgripp are similar to those for other forms of the drug.

Use during pregnancy and lactation is also a contraindication.

Special instructions and interactions with other drugs:

Similar to other Coldrex drugs.

Just do not take this drug while breastfeeding or pregnant, or before reaching 18 years of age.

Method of use of the drug Coldrex maxgripp according to the instructions:

Pour the powder from the bag into a container, add 200 ml of hot water and stir. You can add sugar and cold water.

Adults (persons over 18 years of age): one sachet every 6 hours, but not more than 4 sachets per day.

It is not recommended to take Coldrex Maxgripp for more than five days without consulting your doctor. If symptoms persist, the specialist will prescribe another drug treatment.

Side effects, overdose, storage conditions and dispensing from pharmacies are similar to other Coldrex drugs.

Shelf life: 3 years.

Coldrex broncho

This drug Coldrex is a syrup used as a mucolytic and expectorant for dry cough. The mucus in the pulmonary canals is diluted and easily drained. Relieves discomfort in the lower respiratory tract.

5 ml of Coldrex broncho contains the active substance - guaifenesin, weighing 100 mg.

Other auxiliary ingredients: glucose solution, sodium cyclamate, molasses, sodium benzoate, macrogol, glacial acetic acid, red pepper tincture (capsicum), anise seed oil (star anise), levomenthol, deionized water, camphor and others.

Coldrex Broncho syrup is a viscous dark brown liquid with the smell of anise and licorice. The product comes with a measuring cup.

  • possibility of allergic reactions to components;
  • peptic ulcers of the gastrointestinal tract in the acute stage.

The drug is suitable for children aged three years and older.

For ages 3 to 12 years, 5 ml every 3 hours is recommended, but should not be taken for more than 5 days.

For adults and children over 12 years old, it is recommended to take 10 ml of Coldrex broncho every 2-3 hours, but take no more than 5 days.

If the instructions are followed, Coldrex broncho does not cause adverse reactions.

Sometimes allergic reactions to the components of the drug, as well as drowsiness, are possible.

If you experience any discomfort after taking the drug or allergic reactions, stop taking it and consult your doctor.

If you experience drowsiness from Coldrex broncho, then try to refrain from driving vehicles and machinery.

Overdose and interaction with other drugs:

High doses of the drug cause nausea and vomiting. Therapeutic treatment of indications is used.

Coldrex broncho can be used simultaneously with other medications that are aimed at treating diseases of the bronchopulmonary system. Should not be taken with medications that are intended to suppress cough, as this will make it difficult to expectorate mucus from the pulmonary ducts.

  • do not take the drug for more than five days without a special doctor’s prescription;
  • during treatment, take large amounts of fluid;
  • Coldrex broncho should be taken with caution by people with diabetes, as well as by patients whose disease is accompanied by accumulation of sputum;
  • This drug is prescribed by a doctor for pregnant and lactating women.

Coldrex Broncho is available from pharmacies without a prescription.

Store at a temperature of no more than 30 C and out of the reach of children.

Shelf life: 3 years.

Coldrex junior

Coldrex Junior is a solution for parents that greatly facilitates the fight against colds in children.

The composition of Coldrex Junior is selected in such a way that it has a comprehensive effect on all cold symptoms, which does not require taking additional medications. Children's Coldrex reduces fever, makes you feel better, eliminates a sore throat and soothes.

This drug has a pleasant smell and taste. The dosage of paracetamol contained in it (300 mg) is safe for children.

  • paracetamol, which has an antipyretic and analgesic effect;
  • caffeine, which has a tonic effect;
  • phenylephrine, which relieves swelling of the mucous membranes in the nose and sinuses;
  • vitamin C (ascorbic acid), which supplements the body's need for this vitamin during colds.

Pour the powder from the bag into a container, add 125 ml of hot water and stir. You can add sugar and cold water.

Coldrex Junior can only be taken by children over 6 years of age.

Dosage: one sachet every four hours, but not more than four sachets per day.

It is not recommended to take Coldrex Junior for more than five days without consulting your doctor. If symptoms persist, the specialist will prescribe another drug treatment.

Contraindications, side effects, overdose, interactions with other drugs:

Similar to other Coldrex drugs described above.

This drug is perfect for quickly healing children and has virtually no contraindications.

Does not require a prescription for dispensing from pharmacies.

Store at a temperature of no more than 25 C and out of the reach of children.

Shelf life: 3 years.

Coldrex Knight

Coldrex Knight, according to the instructions, is intended for the treatment of cold symptoms at night.

Coldrex Knight contains paracetamol (500 mg), promethazine and dextromethorphan, which together affect all the symptoms of a cold: nasal congestion or excessive discharge from it, fever, headaches, chills, discomfort in the nasopharynx, muscle pain and joints, cough.

Coldrex Knight is taken at night and once a day. For ease of use, the kit includes a measuring cup.

Children aged 6 years and up to 12 – 10 ml.

Adults and children over 12 years old – 20 ml.

Do not take the drug for more than three days. If symptoms persist, consult a doctor.

Do not drink Coldrex Knight if you take up to 4 g of paracetamol during the day.

Contraindications for use, side effects, overdose and special instructions are similar to the drugs described above.

Pregnant mothers-to-be can use this remedy, but only with the permission of the attending physician. The same applies to use during breastfeeding.

Coldrex immuno

Coldrex immuno is a tablet whose action is aimed at quickly and effectively acting against cold symptoms.

The tablets contain:

  • paracetamol, which has an antipyretic and analgesic effect;
  • caffeine, which has a tonic effect;
  • phenylephrine, which relieves swelling of the mucous membranes in the nose and sinuses;
  • vitamin C (ascorbic acid), which supplements the body’s need for this vitamin during colds;
  • terpinhydrate, which activates the secretion of mucus in the bronchi, helps its release and reduces the strength of cough.

Adults and children over 12 years of age are recommended to take Coldrex Immuno, two tablets 4 times a day. The recommended course of treatment is no more than five days.

Side effects, contraindications, overdose and special instructions are similar to Coldrex tablets.

This drug is prescribed to pregnant and lactating mothers by a doctor.

The “immuno” form is new relative to other Coldrex drugs. Reviews about it are positive.

Can the drug be used during pregnancy and breastfeeding?

Periods of pregnancy and lactation are only a contraindication for taking the drug Coldrex maxgripp.

To take other Coldrex medications during pregnancy and lactation, you need a specialist recommendation.

Coldrex and analogues: which drug is better?

Analogues of the drug are medicines containing paracetamol.

One of the most popular analogues of the drug Coldrex is Fervex. This is also a fairly effective drug for combating the manifestations of colds. However, it is believed that if you are unwell, but not severely, you should take Coldrex. Fervex is taken when you feel unwell.

Another Coldrex analogue, Teraflu, is also often considered. And very often you can come across the following question: “Which is better Coldrex or Theraflu?”

Theraflu also contains paracetamol, just like Coldrex. The pharmacy may offer Theraflu or Coldrex when asked to sell a cold remedy. Therefore, it is impossible to say specifically which is better. Each drug is suitable for a person individually. The price varies between analogues and Coldrex drugs.

Do not forget that Coldrex drugs and their analogues are intended to eliminate cold symptoms. Your doctor will recommend other medications to treat the causes of your cold.

Price

The price of the drug is from 85 to 280 rubles, depending on the dosage form.

The article above and comments written by readers are for informational purposes only and do not encourage self-medication. Consult a specialist regarding your own symptoms and illnesses. When taking any medicine, you should always use the instructions that come with the medicine and your doctor's advice as a guide.

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