Cromohexal instructions for use in the nose

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Cromohexal spray - official instructions for use

Registration number:

Trade name of the drug: Cromohexal

International name: cromoglicic acid

Dosage form:

1 ml dosed nasal spray contains:

Table of contents:

Active substance: sodium cromoglycate 20.0 mg.

Excipients: benzalkonium chloride, sodium chloride, disodium edetate, non-crystallized liquid sorbitol, sodium dihydrogen phosphate dihydrate, disodium hydrogen phosphate dodecahydrate, water for injection.

A transparent, colorless to slightly yellowish solution without mechanical inclusions.

Pharmacotherapeutic group:

An antiallergic agent, has a membrane-stabilizing effect, blocks the entry of calcium ions into the mast cell, preventing its degranulation and the release of histamine, bradykinin, prostaglandins, leukotrienes (including slow-reacting substances) and other biologically active substances. The drug is most effective as a means of prevention. A noticeable clinical effect occurs after a few days or weeks of use.

When administered intranasally, less than 7% is absorbed into the systemic circulation. Connection with plasma proteins – 65%. Not metabolized, excreted by the kidneys and through the intestines unchanged (in approximately equal quantities within 24 hours after use). The half-life is 1.5 hours. Part of the active substance is swallowed (about 1%) and excreted through the gastrointestinal tract without significant absorption.

Prevention and treatment:

  • hay fever
  • allergic rhinitis (including seasonal and/or year-round).
  • hypersensitivity to sodium cromoglicate or any other component of the drug
  • children under 5 years old
  • pregnancy and lactation

The drug should be taken with caution in patients with renal and/or liver failure, or with nasal polyps.

Intranasally. For adults and children over 5 years of age, it is recommended to administer 1 aerosol dose (2.8 mg of sodium cromoglycate) into each nasal passage 4 times a day.

If necessary, you can use 1 aerosol dose up to a maximum of 6 times (maximum 16.8 mg) per day in each nasal passage.

After achieving a therapeutic effect, the frequency of use of Cromohexal can be reduced and the drug can be used only when in contact with allergens (house dust, fungal spores, pollen).

The course of treatment is 4 weeks. Cancellation should be done gradually over 1 week.

To administer the drug, remove the protective cap, insert the spray device into the nostril and press firmly on the spray mechanism. When using the bottle for the first time, press the spray mechanism several times until droplets of liquid appear.

From the respiratory system: irritation or burning of the nasal mucosa, frequent sneezing, cough, rhinorrhea, rarely - nosebleeds.

Allergic reactions: hives, itchy skin, skin rash, swelling of the face, lips or eyelids, difficulty breathing, difficulty swallowing.

Other: unpleasant taste, headache.

There are no data on drug overdose.

Interaction with other drugs

Cromoglycic acid may increase the effectiveness of H1 - histamine blockers

Nasal spray dosed 2%

15 ml or 30 ml in polyethylene bottles with a dosing device closed with a polyethylene cap.

One bottle and instructions for use in a cardboard box.

At a temperature not exceeding 25°C in a place protected from light.

Keep out of the reach of children!

Do not use after the expiration date indicated on the package!

Opened bottles can be used within 6 weeks.

Hexal AG, manufactured by Salutas Pharma GmbH, Industrialstrasse 25, Holzkirchen, Germany

Hexal AG, manufactured by Salutas Pharma GmbH, Industriestrasse 25, 83607, Holzkirchen, Germany

For questions regarding the quality of the drug, please contact:

Source: http://medi.ru/instrukciya/kromogeksal-sprej_5737/

CromoHEXAL

Instructions for use:

Prices in online pharmacies:

CromoHEXAL is an antiallergic drug.

Release form and composition

  • Dosed nasal spray (15 ml (85 doses) or 30 ml (170 doses) in plastic bottles with a dosing device, 1 bottle in a cardboard pack);
  • Eye drops 2% (10 ml in polyethylene dropper bottles, 1 bottle in a cardboard pack);
  • Solution for inhalation (2 ml in polyethylene ampoules, 10 ampoules in a tape, 5 or 10 tapes in a cardboard pack).

All forms of release of the drug are a solution: transparent, colorless or slightly yellowish, without mechanical inclusions.

The active ingredient of CromoHEXAL is sodium cromoglycate, content:

  • 1 dose of nasal spray – 2.8 mg;
  • 1 ml eye drops – 20 mg;
  • 1 ampoule of inhalation solution – 20 mg.

Auxiliary components of the spray and drops: sodium dihydrogen phosphate dihydrate, benzalkonium chloride, non-crystallized liquid sorbitol, sodium chloride, disodium hydrogen phosphate dodecahydrate, disodium edetate, water for injection. Drops contain sodium hydroxide.

Auxiliary component of the solution for inhalation: purified water.

Indications for use

For spray - treatment and prevention:

  • Allergic rhinitis (including year-round and seasonal);
  • Hay fever.

For drops - treatment and prevention:

  • Keratoconjunctivitis;
  • Allergic keratitis;
  • Allergic conjunctivitis;
  • Irritation of the mucous membrane of the eyes due to exposure to irritating factors such as plants, pets, cosmetics or household chemicals, ophthalmic drugs, environmental factors.

For the solution – preventive treatment of asthmatic complaints:

  • Endogenous forms of asthma caused by infection, stress or exercise;
  • Bronchial asthma, including allergic nature.

Contraindications

Regardless of the form of release, CromoHEXAL cannot be used in case of hypersensitivity to the components of the drug.

The spray is contraindicated for pregnant and breastfeeding women.

CromoHEXAL is contraindicated for children in the form of a spray - up to 5 years, in the form of drops and solution - up to 2 years.

CromoHEXAL is prescribed with caution in the following cases:

  • Spray: polyps in the nasal cavity, renal/liver failure;
  • Drops: children under 4 years of age, pregnancy, lactation period.

Directions for use and dosage

CromoHEXAL spray is used intranasally.

Adults and children over 5 years of age are prescribed 1 dose (corresponding to 2.8 mg of sodium cromoglycate) in each nasal passage 4 times a day. If necessary, the frequency of use is increased to 6 times a day. After achieving the required therapeutic effect, the frequency of administration of the drug is reduced and used only in case of contact with allergens (pollen, house dust, fungal spores, etc.).

The course of treatment with the drug in the form of an inhalation solution lasts at least 4 weeks. The drug is discontinued gradually, reducing the frequency of use within 1 week.

Method of using the spray: remove the protective cap from the bottle, insert the spray into the nostril and press firmly on the spray mechanism. Before first use, spray several times into the air until droplets of liquid appear.

CromoHEXAL eye drops for adults and children over 2 years of age are prescribed 1-2 drops into the conjunctival sac of the eye 4 times a day (with an interval of 4-6 hours). If necessary, the frequency of instillations is increased to 6-8 times a day. After achieving a therapeutic effect, the frequency of instillations is reduced and the drug is used only when in contact with allergens.

CromoHEXAL inhalation solution, unless the doctor has prescribed a different treatment regimen, should be inhaled 4 times a day, 1 bottle at regular intervals. If necessary, the single dose is doubled, and the frequency of use is up to 6 times a day. After achieving a therapeutic effect, use the drug as needed.

The course of treatment lasts at least 4 weeks. The dose should be reduced gradually over 1 week.

To open a disposable bottle of inhalation solution, you need to break off its top marked part. CromoHEXAL is inhaled using special inhalers, for example, ultrasonic.

Side effects

When using CromoHEXAL spray, the following side effects are possible:

  • Respiratory system: burning or irritation of the nasal mucosa, rhinorrhea, frequent sneezing, cough; rarely - nosebleeds;
  • Allergic reactions: itching, rash, hives, difficulty swallowing and/or breathing, swelling of the face, eyelids or lips;
  • Other: headache, unpleasant taste.

When treated with CromoHEXAL eye drops, visual disturbances are possible, such as burning and sensation of a foreign body in the eye, lacrimation, meibomitis, conjunctival edema, impaired clarity of visual perception, dry eyes, as well as superficial damage to the corneal epithelium.

When using CromoHEXAL inhalation solution, in rare cases, a cough and mild irritation of the pharynx and trachea appear, which sometimes leads to a reflex spasm of the bronchi. Also possible: skin rash, inflammation of the skin and gastrointestinal tract. These phenomena, as a rule, are mild, short-lived and go away on their own after discontinuation of the drug.

special instructions

CromoHEXAL eye drops reduce the need for ophthalmic medications containing glucocorticoids.

During treatment, you should not wear soft contact lenses (due to benzalkonium chloride in the drug), and hard ones are recommended to be removed 15 minutes before instillation and put on no earlier than 15 minutes later.

During instillation, be careful not to touch the tip of the pipette to the eye or other surfaces.

During the period of using eye drops, special care is required when driving vehicles and performing potentially dangerous types of work that require concentration and quick reactions.

CromoHEXAL inhalation solution is not intended for the relief of acute asthmatic attacks.

In case of long-term treatment, it is necessary to monitor the condition of the kidneys and liver.

If, when using the spray, burning or irritation of the nasal mucosa does not go away or intensifies, the drug should be discontinued.

Drug interactions

Cromoglycic acid may enhance the effect of H1 - histamine blockers.

CromoHEXAL solution should not be inhaled simultaneously with ambroxol or bromhexine.

Analogs

Analogs of CromoHEXAL are: Kromoglin, Krom-Allerg, Lecrolin, Ifiral, Dipolkrom, Vividrin, Intal, Cromolyn, Taleum, Kuzikrom, Kromogen.

Terms and conditions of storage

Store out of reach of children, protected from light at temperatures up to 25 ºС.

Shelf life – 3 years. Drops and spray after opening the bottle can be used for 6 weeks. Vials with inhalation solution are intended for single use.

Conditions for dispensing from pharmacies

Available without a prescription.

Cromohexal 2% eye drops 10ml dropper bottle

Cromohexal drops hl. 2% 10ml n1

CromoHEXAL drops 2% 10 ml

Cromohexal eye drops 2% 10 ml

CromoHEXAL spray 2.8 mg/dose 15 ml 85 doses

Cromohexal spray called. 2.8 mg/dose 85 doses 15 ml n1 (20 mg/ml)

Cromohexal 2% nasal spray 15ml

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

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Source: http://www.neboleem.net/kromogeksal.php

Cromohexal, nasal spray

Analogs

Synonyms that are not commercially available: Kromoglin, Vividrin, Ifiral, Kromosol, Kromogen, Kropoz, Thaleum, Stadaglycine.

Average price online *, 156 rub. (15 ml)

Instructions for use

The product is used for the prevention and treatment of hay fever, as well as seasonal and persistent allergic rhinitis.

Directions for use and doses

The spray is sprayed into the nostrils. The standard dose of the drug for children over 5 years of age and adults is 1 injection into each nasal passage 4 times a day. The frequency of inhalations can be increased to 6 times a day.

After achieving a therapeutic effect, the drug should be used only in case of contact with allergens (house dust, pollen, fungal spores).

The standard course of treatment takes 4 weeks. You need to stop taking the drug smoothly, gradually reducing the frequency of injections over 1 week.

Contraindications

Cromohexal has only two absolute contraindications:

  1. Intolerance to any components in the nasal spray.
  2. Age up to 5 years.

The drug is prescribed with caution to patients who suffer from renal and liver failure and have nasal polyps.

Pregnancy and lactation

Cromohexal is not suitable for the treatment of pregnant and breastfeeding women.

Side effects

The drug can cause a number of side effects from different organs and systems. The most likely ones are:

  • irritation or burning of the nasal mucosa;
  • non-stop sneezing;
  • cough;
  • rhinorrhea;
  • nosebleeds (rare);
  • hives;
  • skin rash;
  • swelling on the face, eyelids, lips;
  • skin itching;
  • labored breathing;
  • difficulty swallowing;
  • headache;
  • unpleasant taste in the mouth.

Composition and release form

The drug is available as a nasal spray in 15 ml or 30 ml bottles with a dispenser. The solution appears colorless or slightly yellowish. There should be no mechanical inclusions in it.

The composition of the drug is as follows:

  • cromoglycate (active substance);
  • benzalkonium chloride;
  • disodium edetate;
  • sodium chloride;
  • sorbitol;
  • sodium dihydrogen phosphate and sodium hydrogen phosphate dihydrates;
  • disodium hydrogen phosphate dodecahydrate;
  • water.

Pharmacology and pharmacokinetics

Cromohexal nasal spray stops allergies.

It works as follows:

  1. Stabilizes mast cell membranes.
  2. It prevents calcium ions from penetrating mast cells, protecting them from degranulation and preventing the release of biologically active substances.

Significant clinical effects appear after a few days or weeks of regular use of the spray.

The product is not metabolized. It is excreted by the kidneys and intestines in its original form. The half-life process is 1.5 hours. The patient swallows approximately 1% of the active substance, but it is then excreted through the gastrointestinal tract without significant absorption.

Interaction with other drugs

When used simultaneously with cromoglycic acid, the effectiveness of Cromohexal may increase. When combining these agents, caution should be exercised.

Best before date

3 years. An open bottle is good for 6 weeks.

Storage conditions

Place inaccessible to children, optimal temperature - up to +25 degrees.

Release from pharmacies

No prescription required.

Reviews

(Leave your feedback in the comments)

[su_quote cite=”Veronica, Vladimir”] I like Cromohexal because it prevents allergies, and I don’t have to suffer from a debilitating runny nose and sneezing. When the plants start to bloom, I simply put the spray in my purse and use it throughout the day. It is much more convenient than taking pills, and there is no drowsiness. [/su_quote]

[su_quote cite=”Galya, Torzhok”] I treat my pollen allergy with tablets. They help get rid of a sore throat, but are powerless against a runny nose. I was looking for inexpensive nasal drops for a long time, and eventually found Cromohexal spray. The bottle has a dispenser - it is more convenient than a pipette. I felt the effect the very next day. The runny nose has not completely gone away, but my nose has stopped itching too much. After about a week, I could already breathe normally. Now Cromohexal is always in my first aid kit [/su_quote]

[su_quote cite=”Yulia, Stavropol”] I cured my vasomotor rhinitis with Cromohexal. What bothered me most was the liquid, colorless snot that flowed in streams and did not allow me to live in peace. After a little over a week they stopped. You need to stop taking the drug gradually, but I just sprayed my nose with the spray for a couple more days to consolidate the effect and called it a day. There was no withdrawal syndrome. [/su_quote]

* — Average value among several sellers at the time of monitoring, is not a public offer

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Cromohexal

Description current as of 08/10/2016

  • Latin name: CromoHEXAL
  • ATX code: S01GX01
  • Active ingredient: Cromoglicic acid
  • Manufacturer: Aeropharm GmbH, Dr. Gerhard Mann, Pharma Stulln (Germany)

Compound

Cromohexal nasal spray contains the active ingredient - cromoglicic acid, as well as additional components: disodium salt EDTA, sodium dihydrogen phosphate, sorbitol, benzalkonium chloride, sodium monohydrogen phosphate, sodium chloride, water.

Cromohexal eye drops contain the active ingredient - cromoglicic acid, as well as additional components: sodium chloride, disodium edetate, benzalkonium chloride, liquid sorbitol, disodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate, water.

Cromohexal for inhalation in the form of a solution contains the active ingredient sodium cromoglycate and purified water as an additional component.

Release form

Several forms of this medicine are produced.

  • Cromohexal nasal spray 2% dosed is a colorless or yellowish solution that does not contain mechanical inclusions. Packaged in 15 ml or 30 ml polyethylene bottles, equipped with a dosing device.
  • Eye drops 2% - a transparent, yellowish solution that does not contain mechanical inclusions. Contained in 15 ml bottles.
  • The solution for inhalation is transparent, yellowish, and does not contain mechanical inclusions. Contained in polyethylene ampoules of 2 ml, which are placed in cardboard packs of 10 pieces.

pharmachologic effect

The medicine has an antiallergic effect.

All forms of Cromohexal include the active component disodium salt of cromoglycic acid. The active substance has a stabilizing effect on the membranes of basophilic granulocytes and also inhibits the entry of calcium ions into the cells. Since under the influence of the drug stabilization of mast cell membranes occurs, there is no degranulation and release of histamine, bradykinin and other mediators of allergy and inflammatory processes into the blood.

This remedy is most effective as a prevention of allergic manifestations. The clinical effect is observed after a few days of using the product.

Pharmacokinetics and pharmacodynamics

After the drug has been administered intranasally, less than 7.5% of the received dose is absorbed into the systemic circulation. 65% bound to plasma proteins. The half-life is 1.5 hours. The active component is eliminated after a day in urine and bile in approximately equal quantities. Metabolism does not occur in the body.

When using eye drops through the mucous membrane of the eye, the active component is absorbed slightly. The level of systemic bioavailability is less than 0.03%.

Indications for use

Cromohexal nasal spray is indicated for allergic rhinitis, which occurs seasonally or throughout the year.

Cromohexal eye drops are prescribed for both the prevention and treatment of keratoconjunctivitis, allergic conjunctivitis, allergic keratitis, as well as irritation of the eye mucosa associated with allergic reactions (the effect of environmental factors, cosmetics, household chemicals, pets, plants, etc.).

The inhalation solution is prescribed for the purpose of preventive treatment of manifestations of bronchial asthma of allergic and non-allergic origin, as well as for endogenous forms of asthma that are associated with stress, infection, and high stress.

Contraindications

Cromohexal in any form is contraindicated for use in case of hypersensitivity to any of the components of the drug.

Allergy eye drops and inhalation solution are not prescribed to children under 2 years of age, nasal spray - to children under 5 years of age. Also, the spray is not prescribed during pregnancy and breastfeeding.

With caution, Cromohexal spray is prescribed to people with liver or kidney failure, as well as to patients with polyps in the nasal cavity.

Side effects

Cromohexal nasal drops can cause the following negative effects:

  • respiratory system: burning or symptoms of irritation of the nasal mucosa, cough, sneezing, rhinorrhea, in rare cases - nosebleeds;
  • allergic manifestations: itching and rash, urticaria, swelling of the lips, face or eyelids, difficulty swallowing or breathing;
  • other manifestations: headaches, bad taste in the mouth.

The inhalation solution can cause the following unpleasant effects:

  • irritation of the trachea and pharynx;
  • a slight cough, in very rare cases - a reflex spasm of the bronchi;
  • skin rash;
  • inflammation of the gastrointestinal tract.

All phenomena are short-lived and disappear after discontinuation of the medication.

Eye drops can cause the following effects:

  • deterioration in vision clarity;
  • burning sensation in the eyes;
  • manifestation of lacrimation;
  • foreign body sensation;
  • swelling of the conjunctiva;
  • dry eyes;
  • meibomite (barley);
  • The lesion of the corneal epithelium is superficial.

Instructions for use of Cromohexal (Method and dosage)

Instructions for nasal spray

It is recommended to administer one dose of the drug into each nasal passage, that is, make one press, 4 times a day.

The maximum permissible dosage is 6 times a day, 1 dose. After the effect has been achieved, you can reduce the number of uses of the product per day. In this case, it is advisable to use a spray when in contact with allergens.

Treatment lasts for 4 weeks, drug withdrawal is carried out gradually over 1 week.

Before using the product, you need to remove the protective cap from the bottle and press the sprayer several times to achieve the optimal dosage. Before using the spray, be sure to thoroughly clean the nasal passages.

Instructions for Cromohexal for inhalation

It is recommended to carry out inhalations 4 times a day, for one inhalation use one bottle of 2 ml. If possible, equal time intervals should pass between inhalations. If necessary, you can increase the frequency of use of the product up to 6 times a day. After the therapeutic effect has been achieved, inhalations can be performed as needed.

When used regularly, Cromohexal solution prevents the manifestation of asthma symptoms, but it does not relieve acute asthma attacks. The course of treatment should be at least 4 weeks, the dose should be reduced gradually over one week. Special inhalers are used for inhalation.

Cromohexal eye drops, instructions for use

It is necessary to instill 1-2 drops of the product into each eye, this must be done 4 times a day. You can increase the number of procedures up to 6-8 times a day. After the therapeutic effect has been achieved, the product can only be used during contact with allergens. For chronic allergies, the duration of treatment is determined by the doctor individually.

Overdose

There is no information about an overdose of Cromohexal.

Interaction

When taken simultaneously, cromoglycic acid can enhance the effect of H1-histamine blockers.

Terms of sale

All forms of the product can be purchased without a prescription.

Storage conditions

All forms of Cromohexal should be stored at temperatures up to 25°C. Keep away from children. Vials of inhalation solution are intended for single use.

Best before date

All forms of medicine can be stored for 3 years; after the package with drops or spray has been opened, the product can be stored for 6 weeks. If stored incorrectly, the solution may turn yellow, in which case it should not be used.

special instructions

The product should not be used after the expiration date indicated on the drug packaging has expired.

If irritation or burning of the mucous membrane occurs, which does not disappear or intensifies, treatment should be stopped.

The inhalation solution should not be used to relieve acute asthma attacks.

When using any form of the drug for a long time, it is necessary to monitor the condition of the patient’s liver and kidneys.

When using Cromohexal eye drops, the need to take ophthalmic agents that contain glucocorticoids is reduced.

Due to the content of Cromohexal benzalkonium chloride drops, you should not wear contact lenses - remove them 15 minutes before instillation of the product and put them on no earlier than the same amount of time after.

The tip of the pipette must not touch the eye; the bottle must be closed after each use.

During treatment, you should be careful when performing activities that require concentration.

Analogs

The drug can be replaced only after prior approval by the attending physician.

For children

The spray cannot be used to treat children under 5 years of age; the solution and eye drops are not prescribed to children under 2 years of age. Cromohexal is used with caution in children under 4 years of age.

During pregnancy and lactation

Despite the fact that the use of Cromohexal for animals did not provoke a teratogenic effect, the drug is not prescribed for pregnant women. The active substance can pass into breast milk, so the medicine is not used during lactation.

Reviews of Cromohexal

Many reviews of the nasal spray, as well as reviews of eye drops, indicate that the drug provides effective prevention of allergy symptoms. A particularly pronounced effect from the use of Cromohexal is observed during seasonal exacerbations of allergies in people prone to such symptoms.

Many parents use the inhalation solution for children who suffer from bronchial asthma to prevent attacks. However, there are also reviews that after using Cromohexal, coughing attacks occurred more often in children. Therefore, it is important that only a specialist prescribes the medicine.

Cromohexal price, where to buy

The price of Kromohexal nasal spray is on average 150 rubles per pack. 15 ml. The price of Cromohexal for inhalation is from 380 rubles. for 50 ampoules. You can also buy Cromohexal eye drops without a prescription, the price of which is on average 100 rubles per 10 ml package.

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Education: Graduated from Rivne State Basic Medical College with a degree in Pharmacy. Graduated from Vinnitsa State Medical University named after. M.I. Pirogov and internship at his base.

Work experience: From 2003 to 2013 – worked as a pharmacist and manager of a pharmacy kiosk. She was awarded diplomas and decorations for many years of conscientious work. Articles on medical topics were published in local publications (newspapers) and on various Internet portals.

A very good product, I puffed twice and forgot))) the price is inexpensive compared to tafen, it helped me

Cromohexal nasal drops. A 5-year-old child was given drops at night, recommended by an allergist for seasonal allergies to flowers, as a result, they woke up with a barking cough, the child was choking, wheezing and wheezing, they called an ambulance, a dexamethasone injection, inhalation of pulmicort, Zyrtec drops, the ambulance team did all this. This is the medicine cromohexal

Tanya: I always use this remedy after a cold, because without it I can go a long time.

Zina: Export helped me with constipation. In addition, I developed dysbacteriosis. Fine .

German: prescribed by a proctologist. After a course (15 tablets), weeping appeared on the legs along the toes.

Ekaterina: Since childhood, when I worry, my stomach shrinks and becomes a lump, and then it hurts.

All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://medside.ru/kromogeksal

CROMOHEXAL

◊ Nasal spray dosed in the form of a clear solution, colorless to slightly yellowish, without mechanical inclusions.

Excipients: benzalkonium chloride, sodium chloride, disodium edetate, liquid non-crystallized sorbitol, sodium dihydrogen phosphate dihydrate, disodium hydrogen phosphate dodecahydrate, water for injection.

85 doses (15 ml) - plastic bottles with a dosing device (1) - cardboard packs.

170 doses (30 ml) - plastic bottles with a dosing device (1) - cardboard packs.

An antiallergic agent, has a membrane-stabilizing effect, blocks the entry of calcium ions into the mast cell, preventing its degranulation and the release of histamine, bradykinin, prostaglandins, leukotrienes (including slow-reacting substances) and other biologically active substances. The drug is most effective as a means of prevention. A noticeable clinical effect occurs after a few days or weeks of use.

When administered intranasally, less than 7% is absorbed into the systemic circulation. Communication with plasma proteins - 65%. Not metabolized, excreted by the kidneys and through the intestines unchanged (in approximately equal amounts within 24 hours after use). T 1/2 – 1.5 hours. Part of the active substance is swallowed (about 1%) and excreted through the gastrointestinal tract without significant absorption.

Prevention and treatment:

— allergic rhinitis (including seasonal and/or year-round).

- hypersensitivity to sodium cromoglycate or to any other component of the drug;

- children under 5 years of age;

- pregnancy and lactation period.

with caution in patients with renal and/or liver failure, or with nasal polyps.

For adults and children over 5 years of age, it is recommended to administer 1 aerosol dose (2.8 mg of sodium cromoglycate) into each nasal passage 4 times a day.

If necessary, you can use 1 aerosol dose up to a maximum of 6 times (maximum 16.8 mg) per day in each nasal passage.

After achieving a therapeutic effect, the frequency of use of the drug can be reduced and CromoHEXAL can be used only when in contact with allergens (house dust, fungal spores, pollen).

The course of treatment is 4 weeks. Cancellation should be done gradually over 1 week.

To administer the drug, remove the protective cap, insert the spray device into the nostril and press firmly on the spray mechanism. When using the bottle for the first time, press the spray mechanism several times until droplets of liquid appear.

From the respiratory system: irritation or burning of the nasal mucosa, frequent sneezing, cough, rhinorrhea, rarely - nosebleeds.

Allergic reactions: hives, itchy skin, skin rash, swelling of the face, lips or eyelids, difficulty breathing, difficulty swallowing.

Other: unpleasant taste, headache.

There are no data on drug overdose.

Cromoglycic acid may increase the effectiveness of H1-histamine blockers.

If irritation or burning of the nasal mucosa does not go away or intensifies, discontinuation of treatment is necessary.

Contraindicated during pregnancy and lactation.

Contraindicated in children under 5 years of age.

Store the drug out of the reach of children and protected from light at a temperature not exceeding 25°C.

Shelf life: 3 years. Do not use after the expiration date indicated on the package. Opened bottles can be used within 6 weeks.

To ask a question about the project or contact the editors, use this form.

Source: http://health.mail.ru/drug/cromohexal/

Cromohexal for children in the form of drops and solution for inhalation

Cromohexal is a drug available in such forms as inhalation solution, nasal spray, eye drops. An antiallergic medication that is a mast cell stabilizer. It contains cromoglycic acid disodium salt. This product can be taken by children and adults. The instructions indicate age and dosage, so read them carefully before use.

What is Cromohexal intended for?

Cromohexal nasal spray, eye drops and inhalation solution are intended for children with allergies. The medicine can be used by adults and children (the instructions prescribe at what age a child can take the medicine) for preventive purposes in advance, before the seasonal period, when allergies manifest themselves in acute form. Use in therapy will help eliminate itching, swelling, inflammation and sneezing, relieving the allergy sufferer of unpleasant symptoms and significantly alleviating his condition.

The inhalation solution is used in preventive treatment for bronchial and endogenous asthma caused by infection, physical activity or stress.

Nasal spray for prevention and treatment:

Eye drops for prevention and treatment:

  • For allergic conjunctivitis;
  • For keratoconjunctivitis;
  • For allergies (to chemical cleaning products, saliva and animal hair, environmental phenomena, cosmetics, medications);
  • With increased eye strain.

Cromohexal will help with acute runny nose

Few domestic doctors know about the use of the drug for acute rhinitis during a viral disease. Cromohexal blocks the release of bradykinin, leukotrienes and histamine. It is these substances that contribute to the appearance of an acute runny nose during a viral disease. If you use this remedy, the runny nose will disappear after 1-3 days, and not after 7 days, as usually happens.

Cromohexal has proven itself as an effective anti-allergenic agent. The positive thing is that the medicine is not hormonal.

Reviews about it are both positive and negative, due to the fact that the drug has many side effects. Therefore, the drug should be taken only in the amount indicated in the instructions. You cannot self-medicate based on reviews, since each person has an individual tolerance to drugs and its components. This may lead to an unfavorable outcome.

Great care should be taken when giving medication to a small child. Parents need to study all the information up to what age children should not take the medicine. You need to be especially careful when using eye drops for babies in their second year of life; observe the children’s behavior. If you feel that he has become more capricious or is not behaving as usual, immediately contact your doctor, who will take the necessary measures and, if necessary, stop the medication.

Instructions for use

Important: use the medication in the dosage prescribed by the instructions or the attending physician.

Solution for inhalation

The procedure should be carried out using an inhaler 4 times a day, one cap (2 ml or 20 mg) at regular intervals (unless the doctor has prescribed a different treatment regimen). If necessary, the dose is increased by 2 times, and the frequency of administration by up to 6 times. After the drug has achieved the desired result, it is used as required. The therapeutic course using inhalation lasts at least 4 weeks. Improvement occurs after 2-4 weeks. The dose is reduced gradually. The duration of therapy is determined by the doctor.

Spray in the nose

Prescribed for adults and children over 5 years old 4 times a day, 1 injection into the nostril. It is possible to increase up to 6 times (but no more) in each nostril. The course of drug therapy lasts for 4 weeks. The dose is reduced gradually.

Eye drops

For adults and children over 2 years old, drop 1-2 drops into both eyes 4 times a day with an interval of 4 to 6 hours. If necessary, the dose is increased to 6-8 times.

Side effects and contraindications

If negative side effects appear as a result of taking Cromohexal, the medication should be stopped immediately and consult a specialist.

Solution for inhalation:

  • The trachea and pharynx are irritated;
  • A rash appears on the skin;
  • Dizziness and headaches occur;
  • Bronchial spasms;
  • Coughing;
  • Problems with the gastrointestinal tract.
  • Constant sneezing;
  • Skin itching;
  • Blood from the nose;
  • Burning in the mucous membranes of the nose;
  • Coughing;
  • Swelling on the face;
  • Difficulty breathing or swallowing.
  • Dry eyes appear;
  • The clarity of vision changes;
  • Tearing;
  • Minor changes in the outer layer of the cornea;
  • Burning eyes.

There is no information about cases of overdose, but it must be taken in the amount specified in the instructions. This drug is contraindicated for those who are intolerant to the components of the drug. There are also age restrictions for children (up to 2 years - eye drops, up to 5 years - spray). Nasal spray is contraindicated during the first semester of pregnancy and during breastfeeding. Those who have kidney or liver problems should take the product with extreme caution, and the spray should be taken by those who have nasal polyps.

Analogs

There are many analogues of the drug:

This medicine is available and can be purchased at almost every pharmacy without a prescription. But before buying it, consult your doctor. The pricing policy of the product depends on the region in which the medicine is sold and in which pharmacy company.

  • Solution for inhalation – rub;
  • Spray in the nose – rub;
  • Eye drops – rub.

Source: http://lecheniedetej.ru/preparaty/ot-allergii/kromogeksal.html

Cromohexal for children: instructions for use

CromoHEXAL is one of the drugs prescribed for allergies. Is it allowed in children and in what dosage is it used in children?

Composition and release forms

CromoHEXAL is presented in the following types:

  • Eye drops. They are available in plastic bottles of 10 milliliters.
  • A solution that is used for inhalation. It is placed in polyethylene ampoules with a capacity of 2 ml, connected into strips of ten pieces. One pack includes 5-10 ribbons.
  • Spray in the nose. It is presented in plastic bottles that have a dispensing device. One bottle contains 15 ml of medication (of which the patient receives 85 doses) or 30 ml of liquid (it includes 170 doses).

Any of the variants of CromoHEXAL is a colorless or slightly yellowish solution. It is transparent and does not include any suspended matter. The active ingredient in all forms is sodium cromoglycate. In 1 ml of eye drops and in each ampoule of solution, this compound is presented in a dosage of 20 mg. One dose of spray contains 2.8 mg of cromoglycate.

Additionally, the drops and spray contain water, benzalkonium chloride, sorbitol and other compounds. In the solution for inhalation use, the active ingredient is supplemented only with purified water.

Operating principle

Cromoglycate has the property of stabilizing membranes in cells called mast cells. The drug prevents calcium ions from entering such cells, as a result of which histamine, prostaglandins and other active compounds involved in the allergic reaction are not released from them. Since the medicine does not begin to act immediately, but after several days (or even weeks), it is most often used as a prophylactic agent.

Indications

CromoHEXAL is dripped into the eyes for allergic forms of keratitis, conjunctivitis or keratoconjunctivitis. The drug is used for allergic reactions to household chemicals, dust particles, eye drops, cosmetics, pollen, animal hair and other allergens. A dosed spray is in demand for hay fever or allergic rhinitis, as well as for adenoids. CromoHEXAL inhalations are prescribed for bronchial asthma.

At what age is it prescribed?

Eye drops and solution are used in children over 2 years of age. The nasal spray is approved for children over 5 years of age.

Contraindications

Neither form of medication is prescribed for hypersensitivity to their ingredients. CromoHEXAL in the form of eye drops is used with caution in children under 4 years of age, and in the form of a spray - for serious liver diseases, nasal polyps and renal failure.

Side effects

The use of CromoHEXAL may cause headaches, irritation of the mucous membrane, urticaria, cough and some other symptoms. When they appear in a child, you need to tell your doctor about it.

Instructions for use

  • The solution is administered using a nebulizer 4 times a day with equal intervals between procedures. For each inhalation, take 1 ampoule. If required, the single dosage is doubled and the frequency of inhalations is increased to six per day.
  • The spray is sprayed into the nose, one dose into each nostril. The procedure is performed 4-6 times a day. As soon as the therapeutic effect becomes noticeable, the frequency of use is reduced and the medicine is administered into the nose only in case of contact with allergens.
  • The duration of use of the spray or solution should be at least 4 weeks with gradual withdrawal of the medication over the course of a week.
  • Drops are instilled 1-2 into each eye every 4 or 6 hours. The medication is used 4, 6 or 8 times a day. When the condition improves, the drug continues to drip only when interacting with the allergen.

Drug interactions

The drug enhances the therapeutic effect of antihistamines.

Inhalation of CromoHEXAL should not be combined with inhalation administration of bromhexine or ambroxol.

Terms of sale and storage

  • All forms of CromoHEXAL are sold in pharmacies without a prescription. One bottle of eye drops costs about rubles, and the price of a nasal spray averages 150 rubles.
  • At home, medications should be stored at room temperature in a place hidden from children, away from sunlight.
  • The shelf life of all forms is 3 years, but the medicine from an opened bottle of spray or drops should be used within 6 weeks after the first use. Each inhalation ampoule is used for one procedure.

Reviews

There are mostly good reviews about treatment with CromoHEXAL. The drug is called an effective preventive medicine for allergies and it is noted that it is not addictive, and adverse reactions are extremely rare.

Analogs

Other drugs with the same effect on mast cells can replace CromoHEXAL:

  • Ketotifen. This remedy is given in syrup from 6 months of age, and in tablets from 3 years of age.
  • Zaditen. These eye drops are used from the age of 12.
  • Intal. Inhalations with such capsules are allowed from 2 years of age, and the aerosol is used in children over 5 years of age.
  • Tailed Mint. This dosed aerosol is used from the age of two.

Also, in case of an allergic reaction, the child may be prescribed antihistamines, for example, Zyrtec, Fenistil, Erius or Claritin.

Dr. Komarovsky will tell you how to determine what a child may be allergic to in the video below.

Watch the program of the famous pediatrician Evgeniy Komarovsky about anti-allergy drugs.

All rights reserved, 14+

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Source: http://www.o-krohe.ru/antigistaminnye-preparaty/kromogeksal/

How to use Cromohexal drops?

Allergic rhinitis is familiar to many. This is an unpleasant inflammation that causes a person severe discomfort. Antihistamines, which have gained wide popularity in Russia due to their quick results, can be used to cure this disease. One of these drugs is Cromohexal.

The medication has a pronounced effect and in a short time eliminates allergy symptoms, clears the airways and normalizes the functioning of the mucous membrane. People of all ages are allowed to take this medication, but the drug has some side effects and contraindications. Study them before using Cromohexal during pregnancy or in any other case.

About Kromohexal drops

Kromohexal nasal drops are an effective remedy for acute rhinitis or allergic rhinitis. Metered nasal spray is available in fifteen or thirty milliliters for 85 and 170 doses, respectively. The drug is sold in plastic bottles together with a dosing device.

In addition to the nasal spray, there is an identical preparation for the eyes and an inhalation solution. All medications are made in the form of a transparent solution. The composition of the medication does not include mechanical inclusions.

The active ingredient of the nasal spray is sodium cromoglycate.

This component normalizes the functioning of the membrane of sensitized mast cells.

This allows you to slow down the activation of calcium ions. Thus, the cells are freed from harmful viruses and infections.

Sodium cromoglycate effectively fights inflammation such as:

  • bronchial asthma;
  • atopic asthma;
  • asthmatic triad;
  • Chronical bronchitis.

The use of such a substance is justified in the case of food allergies, as well as ulcerative colitis, diseases of the mucous membrane of the sigmoid and rectum, purulent inflammation of the mucous membranes, a group of inflammations in which a large number of accumulations of mast cells are formed in the tissues.

Sodium cromoglycate is often used for seasonal allergic reactions, as well as in cases of exacerbation of seasonal allergic rhinoconjunctivitis.

Excipients of the drug include:

  • an inorganic compound of acid salt produced from the alkali metal sodium - sodium dihydrogen phosphate dihydrate. Such a compound quickly dissolves in water, forming water molecules;
  • an antiseptic medicinal component that actively acts when the body is damaged by fungal viruses or antiprotozoal disorder - benzalkonium chloride. The substance has a contraceptive effect and destroys harmful viruses;
  • syrup with a high content of mannitol - sorbitol, liquid, non-crystallized. Such a component interferes with crystallization;

sodium salt of hydrochloric acid, better known as table salt, is the main substance of sodium chloride;

  • an inorganic compound that produces sodium metal salt and phosphoric acid. Dissolving in water, disodium hydrogen phosphate tadodecahydrate forms crystalline hydrates;
  • active natural component that has an active effect on the immune system - disodium edetate. The substance has an antiviral effect and activates the body’s defense against harmful microelements;
  • purified water.

    • In addition, the drops contain sodium hydroxide - this is the most common alkali, the medicinal effects of which can quickly eliminate the symptoms of inflammation.

    In what cases can Cromohexal be treated?

    A large list of substances can eliminate inflammatory processes at the very initial stage of the disease.

    But when using this drug in case of an acute illness, you should expect an effective result.

    The medicine is prescribed for the following ailments:

    1. In case of year-round or seasonal allergic rhinitis.
    2. Seasonal allergic rhinoconjunctivitis.
    3. Serious allergic reactions to local irritants (flowers, dust, pets, etc.).
    4. Hay fever.
    5. Bronchial asthma.
    6. Disease of the conjunctiva with inflammation of the cornea of ​​the eye.
    7. Allergic keratitis.
    8. Allergic conjunctivitis.
    9. Severe irritation of mucous membranes.
    10. Preventive measures.

    It is recommended to use the medication only after you are sure that there are no allergic reactions to the components of the drug. It is best to establish the absence of hypersensitivity with the help of your doctor.

    Contraindications

    The use of the medication must be authorized by the attending physician.

    Since the drug has several contraindications, it is necessary to pay attention to this aspect.

    1. Do not use the medicine if you are particularly sensitive to the components of the medicine.
    2. Do not use the product if you are pregnant without a doctor's prescription.
    3. The product should not be used when treating children under five years of age. In extremely rare cases, treatment of younger children in the form of drops or solution is allowed.

    In case of renal failure, it is necessary to consult a doctor, since the possibility of using the medication in this case must be decided by the attending physician. Treatment with this drug is necessary with special care for polyps in the nasal passages.

    Side effects

    After purchasing the drug, read the instructions for using Cromohexal nasal drops, as the drug has side effects.

    In order to protect yourself from unwanted consequences, familiarize yourself with them, as well as with the correct dosage of the medicine.

    1. In case of burning in the mucous membrane or severe irritation, rinse your nose with warm water. It is not advisable to instill the drug in the future.
    2. There may be copious and constant discharge from the nasal passage.
    3. Strong discharge of mucous exudate several hours after application.
    4. Pay attention to side effects if, after administration of the drug, the patient has a severe cough or sneezing. The administration of the drug must be stopped in the future.
    5. In rare cases, patients complained of nosebleeds, as well as a feeling of itching and a rash. Other side effects include difficulty swallowing, swelling of the mucous membrane, breathing problems, headaches and temple pain, and loss of smell.

    Most often, unpleasant symptoms go away on their own after stopping the course of treatment.

    In especially rare cases, blurred vision, a feeling of a foreign object in the sinuses, pressure in the nose, changes in blood pressure, lacrimation, swelling of the conjunctiva, and a feeling of dry eyes are noted.

    These manifestations are extremely rare, but if they occur, you should consult a doctor for medical help. After consultation, it is necessary to replace the drug with another medicinal component.

    special instructions

    This medication is not intended for long-term treatment. Therefore, it is necessary to monitor the course of therapy.

    It is important to note that Cromohexal nasal spray is not able to completely cure the manifestations of acute asthmatic attacks, so in this case complex treatment under the supervision of doctors is required.

    After treatment, it is necessary to check the condition of the kidneys and liver. Thus, you will make sure that there are no onset of unwanted processes in the body.

    If mucous discharge increases when the drug is administered, its use should be discontinued.

    How to use the drug

    In each case, the use of the drug should be monitored by a qualified physician. It is especially important to consult a specialist if you are pregnant or treating young children.

    During pregnancy

    In case of pregnancy, the drug can be used only after personal consultation with your doctor.

    There have been no clinical studies on the effect of the medication on the fetus, so you should not risk your own health.

    It is necessary to make sure that there is no risk to the fetus and only then use this remedy.

    The spray is used only locally. Before administering the drug, clean the nasal passages using special medications. The drug should be administered according to the dosage prescribed by the doctor.

    Typically, the use of the drug during pregnancy involves one injection three times a day. In case of acute inflammation, a larger number of injections are prescribed, but this issue is discussed individually with your attending physician.

    After signs of inflammation have reduced, it is necessary to reduce the number of medications taken, and within a few days stop injecting altogether.

    When treating children

    Cromohexal should be used with caution in cases of inflammation of acute allergic rhinitis in children.

    Treatment of children under five years of age with this drug is strictly prohibited.

    Kromohexal nasal drops for children should be used with extreme caution.

    At older ages, one injection every five hours is prescribed.

    In case of complications of inflammation, the frequency is increased to every three hours. Immediately after the severity of symptoms decreases, it is necessary to use the drug less frequently. In this case, two sprays per day are sufficient.

    In the future, the drug should be used only if there is direct exposure to the allergen.

    Keep in mind that if you take the drug in the form of inhalations, the treatment period increases to one month. It is necessary to stop using the drug immediately, but to slowly reduce its effect over seven days.

    Reviews

    Reviews of Cromohexal for the nose seem very positive.

    Sergey Ivanov: “I used Cromohexal for an allergic reaction in the form of a runny nose to a cat. I had never noticed such a symptom before, but due to my line of work I had to live in the same apartment with a cat for one month. On the third day of stay, itching and severe nasal discharge appeared. The pharmacist at the pharmacy advised me to purchase this particular spray. I used it one spray at a time throughout my stay.”

    Kristina Getmanenko: “When I was pregnant with my second child, my immunity was greatly reduced and an allergy to pollen appeared, although I had not noticed such symptoms before. As directed by the doctor, I used Cromohexal. Sprayed twice a day for five days. After this time everything passed.”

    Conclusion

    Treatment of allergic rhinitis begins with identifying the cause of inflammation. It is impossible to start therapy without an accurate diagnosis and identification of all symptoms. Therefore, at the first signs of this disease, seek medical help.

    After this, the patient will be prescribed complex treatment using medications. Most often, patients only need to inject Cromohexal, since this drug has a powerful effect. But it is not recommended to use the product yourself, as you can provoke dangerous consequences.

    Directory of main ENT diseases and their treatment

    All information on the site is for informational purposes only and does not claim to be absolutely accurate from a medical point of view. Treatment must be carried out by a qualified doctor. By self-medicating you can harm yourself!

    Source: http://gorlonos.com/kapli/kak-primenyat-kapli-kromogeksal.html