Rinofluimucil - a unique combination for runny nose and sinusitis
What are we used to using for a runny nose? Vasoconstrictor drops, which have no therapeutic effect at all, and moisturizing saline solutions - that’s all the variety.
Table of contents:
- Rinofluimucil - a unique combination for runny nose and sinusitis
- Strength in combination
- Indications: when is Rinofluimucil used?
- How to take Rinofluimucil?
- Caution: medicinal rhinitis
- Deviation from the instructions: Rinofluimucil for inhalation
- Preparation of a solution for inhalation - secrets of a pharmacist
- Use of Rinofluimucil for children
- Side effects
- When is Rinofluimucil contraindicated?
- Medicinal metamorphoses
- How to store?
- Rinofluimucil's analogs
- When is Nimesil used?
- When is Rotokan used for inhalation?
- The content of the article
- Pharmacological properties of "Rotokan"
- Benefits of inhalation treatment
- How to prepare Rotokan for inhalation
- Dexamethasone injections - when are they necessary? Indications and precautions
- Properties of the drug and its use
- How to use Dexamethasone injections
- Treatment of joint diseases
- Treatment of allergic diseases
- Side effects and contraindications
- Advantages and disadvantages
- When is Fukortsin solution used?
- Description of the drug
- Indications for use
- How to wash Fukortsin from skin?
- Contraindications to the use of the drug
- Side effects
- special instructions
- Superphosphate: characteristics, when and on what soils to use, preparation of solution
- When is superphosphate used?
- On what soils should I use it?
- Instructions for use
- Application
- Use with other fertilizers
- Types of superphosphates
- Superphosphate extract
- Application of superphosphate for private plants
- Potato
- Tomatoes
- When to use
At the same time, on the pharmaceutical market there is a completely unique complex spray Rinofluimucil, which alleviates rhinitis and rhinosinusitis, regardless of their origin.
>> The site presents an extensive selection of medications for the treatment of sinusitis and other nasal diseases. Enjoy it for your health! <
Strength in combination
The drug, which is produced by the Italian company Zambon, contains two active ingredients that enhance each other’s effects: acetylcysteine and tuaminoheptane.
Acythelicysteine is a synthetic substance whose structure contains a free sulfhydryl group. Thanks to its presence, the drug has a pronounced mucolytic effect, breaking the disulfide bonds that “hold together” acidic mucopolysaccharides. Namely, they are the main link that ensures the thick, viscous consistency of sputum and nasal mucus. In addition, acetylcysteine reduces the inflammatory process and even binds free radicals, providing an antioxidant effect.
Tuaminoheptane is a drug that is used only in combination with other drugs. It has vasoconstrictor properties, and its peculiarity is its short-term action. Therefore, tuaminoheptane has not found use as a vasoconstrictor drug to facilitate nasal breathing.
Tuaminoheptane works well as a component of the complex drug Rinofluimucil. Due to the fact that it provides a rapid, albeit rather short-term, vasoconstriction, the second substance of the combination, acetylcysteine, can penetrate into the deepest parts of the nasal cavity and effectively thin out thick mucus.
Indications: when is Rinofluimucil used?
Rinofluimucil is prescribed for the most common diseases of the nasal mucosa and paranasal sinuses, including those accompanied by the release of thick purulent discharge.
Among the pathologies for which Rinofluimucil nasal spray can be used:
- acute, as well as subacute rhinitis - inflammation of the nasal mucosa. It is advisable to use Rinofluimucil for purulent discharge that requires liquefaction;
- chronic rhinitis;
- sinusitis, that is, inflammation of the paranasal sinuses. As a rule, we are talking about sinusitis - both acute and chronic sinusitis.
- vasomotor rhinitis, in which impaired nasal breathing is caused by thickening of the nasal mucosa. We emphasize that Rinofluimucil only alleviates the condition of vasomotor rhinitis, but the disease itself is usually treated surgically.
How to take Rinofluimucil?
According to the instructions for Rinofluimucil, it is intended for irrigation of the nasal cavity. The drug is a solution with a menthol odor, placed in a bottle with a spray nozzle. Preparation for using the spray is simple: just remove the cap from the bottle and sprayer, and then remove the protective cap from the latter. There is no need to calibrate it, that is, spray a “test” dosage, as in some other dosed preparations for irrigating the nose or throat. That's all the wisdom that describes how to take Rinofluimucil.
Note that Rinofluimucil is a dosed nasal spray. When it is sprayed, a strictly defined dose of the medicinal composition is released. After pressing the cap with the drug, one milliliter of solution is released, which contains:
- acetylcysteine 10 mg;
- Tuaminoheptane sulfate 5 mg.
The average dosage for adults, regardless of the type of disease, is 2 doses of the drug (that is, two presses on the spray) in each nasal passage. Frequency of application 3-4 times a day.
For children, the spray is prescribed in a dosage half as much as for adults: one dose 3-4 times a day.
Important: the course of treatment with Rinofluimucil should not exceed seven days!
Caution: medicinal rhinitis
The main condition for the development of this side effect is to use the medicine for more than seven days in a row. This time is quite enough for the body to get used to the continuous flow of adrenergic agonists into the nasal cavity and “forget how” to breathe without them. Drug-induced rhinitis, or withdrawal rhinitis, which is sometimes called rebound rhinitis, is characterized by chemical damage to the nasal mucosa.
Long-term exposure to Rinofluimucil spray and its component tuaminoheptane sulfate on the mucous membrane causes not only dilation of blood vessels in it, but also changes at the cellular level. Therefore, drug-induced rhinitis is a serious consequence of improper therapy, which causes no less problems than the initial sinusitis or viral rhinitis. To prevent drug-induced damage to the nasal mucosa, the recommended course of treatment with alpha-agonists should not be exceeded.
It is safe to treat with tuaminohepatone sulfate and other vasoconstrictor drugs for no longer than seven, maximum ten days.
Deviation from the instructions: Rinofluimucil for inhalation
The instructions for use of Rinofluimul provide only one option for prescribing the drug - in the form of irrigation of the nasal cavity. However, due to the fact that the drug does not contain sugars, it can also be used for inhalation. Particles with a size of no more than 10 microns enter remote areas of the nasal cavity and maxillary sinuses. This should be taken into account when choosing a nebulizer for nasal inhalation.
The inhalation route of administration is characterized by the highest efficiency. The rapid and finely dispersed delivery of active substances directly to the site of inflammation allows you to reduce drug losses and achieve the highest possible concentration. Therefore, nebulizer inhalation treatment with Rinofluimucil is an excellent alternative to traditional nasal drops or spray.
Fine particles of acetylcysteine and tuaminoheptane sulfate arriving during the nebulizer administration of Rinofluimucil are evenly distributed in the nasal cavity and maxillary sinuses. Thanks to this, thick nasal secretions are removed, which accumulated in the most remote parts of the nasal cavity and in the paranasal sinuses. Reducing swelling helps to increase the size of the openings between the maxillary sinuses and the nasal cavity and facilitate the removal of secretions.
Preparation of a solution for inhalation - secrets of a pharmacist
Yes, the benefits of inhaled drug administration are undeniable. But what about Rinofluimucil, which is available in only one form - a spray? How to prepare an inhalation solution when there is no solution as such at hand? In fact, everything is simple, and domestic craftsmen have long learned to solve such “problems.”
We already know that each dose of Rinofluimucil contains exactly 1 ml of solution. To obtain a solution for inhalation, you need to spray one or two doses of spray into a container (one for a child and two for an adult) and dilute them with a neutral solution. It is best to use three milliliters of sodium chloride 0.9%, and the medicine for inhalation with Rinofluimucil can be considered ready. To obtain a therapeutic effect, it is enough to carry out two inhalations per day, the course of therapy is seven days.
Inhalations with Rinofluimucil can be combined with inhalation administration of saline or antiseptic solutions. This will increase the final effectiveness of therapy.
Use of Rinofluimucil for children
According to the official instructions, Rinofluimucil can be used to treat all children over three years old without worry or worry. Information about the possibilities of using the drug for patients under three years of age is rather scarce: in the chapter “Special Instructions” it is dryly noted that at this age Rinofluimucil should be used with caution. Let's decipher the encoded messages that the manufacturer hid behind common phrases that are incomprehensible to mere mortals.
So, if the instructions do not explicitly say that the drug is prohibited for use in children under 3 years of age, therefore, a priori it can be used in this category of patients. Another important fact in favor of Rinofluimucil, prescribed for the treatment of young children, is that the drug, when applied topically, does not have a systemic effect. This means that it is not absorbed into the blood at all and is therefore particularly safe. But why then is the manufacturer trying to get around the rough edges and relieve itself of responsibility for prescribing Rinofluimucil to young children?
It's actually simple.
To “give the go-ahead” for the use of a drug in any “special” category of patients—be it infants, pregnant women, or patients with severe systemic disease—the manufacturer must prove the drug’s safety in clinical trials.
Studies of the use of Rinofluimucil in newborns and young children have not been conducted. That is why, despite all the facts that indicate the potential safety of the spray, the instructions contain a warning that frightens parents.
We would like to add that all nasal and throat sprays should be used with caution when treating children under one year of age. This is due to the likelihood of developing bronchospasm in response to a sudden entry of the drug solution into the nasopharynx.
Side effects
In the vast majority of patients, Rinofluimucil is well tolerated. However, like any medicine, it can cause adverse events. The side effects of Rinofluimucil are quite traditional for vasoconstrictors: after its use, tachycardia, a slight increase in blood pressure, and dryness of the nasopharyngeal mucosa may develop. But as a rule, these adverse events are not dangerous and do not serve as a reason to stop treatment.
When is Rinofluimucil contraindicated?
Despite the relatively high safety, there are several conditions in which Rinofluimucil is strictly contraindicated. Among them:
- angle-closure glaucoma. Additional vasoconstriction as a result of the use of alpha-agonists can contribute to the deterioration of the condition and a sharp blockage of outflow from the eye. As a result, intraocular pressure quickly and significantly increases, which is fraught with atrophic changes in the optic nerve;
- thyrotoxicosis;
- hypersensitivity to acetylcysteine or tuaminoheptane sulfate.
Particular caution when prescribing Rinofluimucil should be exercised by people suffering from cardiovascular diseases: arterial hypertension, severe angina pectoris and frequent extrasystole. In such cases, the use of any vasoconstrictor should be monitored by a cardiologist.
It should be remembered that acetylcysteine can increase the likelihood of bronchospasm, so patients with bronchial asthma should monitor their condition after irrigating their nose with Rinofluimucil. If signs of bronchospasm appear, the drug is immediately discontinued.
The safety of Rinofluimucil during pregnancy and breastfeeding has not been studied. Therefore, the official instructions state that the drug is allowed only in the most extreme cases, when the benefit significantly outweighs the possible risk to the child. In practice, neither ENT doctors nor obstetricians see much sense in using Rinofluimucil, and the question of the advisability of prescribing it to pregnant women is usually not even raised.
Medicinal metamorphoses
Rinofluimucil may react with some drugs, and in particular with antidepressants. This is due to the fact that alpha-agonists (in our case, tuaminoheptane sulfate) can increase the likelihood of developing side effects characteristic of some antidepressants.
That is why Rinofluimucil should not be used simultaneously with:
- MAO inhibitors (antidepressants pyrazidol and others).
- tricyclic antidepressants, of which amitriptyline is most often used.
The restriction on the use of Rinofluimucil with antidepressants remains until 14 days after the end of treatment for depression with MAO inhibitors and amitriptyline.
There is another limitation associated with the ability of Rinofluimucil to constrict blood vessels. Reducing the lumen of blood vessels can weaken the effect of hypotonic drugs. Therefore, hypertensive patients receiving constant treatment with antihypertensive drugs should remember this property of Rinofluimucil before starting its use.
How to store?
The drug is unpretentious: it retains its properties at a temperature of 15–25°C. However, there is one nuance that it is better not to forget about. According to the instructions, the shelf life of a vial of Rinofluimucil after initial opening should not exceed 20 days. Otherwise, there is a possibility of contamination of the solution with pathogenic flora, which can lead to the development of additional inflammation in the nasal cavity.
Rinofluimucil's analogs
Many buyers in times of crisis and rising exchange rates are interested in one question: are there cheaper analogues of Rinofluimucil for children and adults? Unfortunately, there is nothing to please. Domestic and even foreign enterprises producing generic drugs have not yet mastered the production of a drug containing acetylcysteine and tuaminoheptane sulfate. Rinofluimucil was and remains a unique, safe combination that makes breathing easier and truly cures a runny nose at any age.
Source: http://gaimoriti.ru/medicamenty/rinofluimucil.html
When is Nimesil used?
When is Nimesil used?
When Nimesil is used, any competent pharmacist or experienced mother will tell you. After all, Nimesil is one of a number of NSAIDs. Nimesil belongs to the group of non-steroidal anti-inflammatory drugs. Nimesil is used as an analogue of aspirin, analgin, baralgin, paracetamol or ibuclin. It makes sense to use Nimesil only at the very beginning of acute respiratory diseases. It relieves the initial symptoms of acute respiratory infections: fever, drowsiness, weakness, discharge from the nose and throat. Something between analgesics (pain relievers) and antipyretics. Nimesil is one of the cheapest drugs, available in powder form. One sachet is poured into two hundred milliliters of boiled water. If a person does not have an allergic reaction to this group of drugs, does not have erosive gastritis and gastric and duodenal ulcers, then the use of this drug will be practically without a trace for him. You should not hope that the drug will kill bacteria or viruses that entered the body during illness; the drug only reduces the primary symptoms of a cold so that the body can cope with a weakened illness. However, such treatment itself, in turn, can reduce immunity and prolong the disease.
Source: http://zadavalka.ru/kogda-primenyayut-nimesil
When is Rotokan used for inhalation?
The content of the article
- When is Rotokan used for inhalation?
- How to use tea tree oil
- Benefits of tea tree oil
Pharmacological properties of "Rotokan"
The drug is a dark brown liquid extract with a specific odor. In its composition, it includes a mixture of plant phytoraw materials: chamomile flowers, calendula and yarrow herb, which in combination have an anti-inflammatory, antispasmodic, analgesic, bactericidal and healing effect.
Benefits of inhalation treatment
This form of using herbal medicine has a number of advantages: an accessible way to alleviate the patient’s condition; impact directly on the site of inflammation; possibility of combination with other drugs; additional oxygen inhalation.
How to prepare Rotokan for inhalation
The use of this product for inhalation has not yet been widely used, and the instructions supplied with it do not contain such information. Consultation on this issue can be obtained from your attending physician, who will provide detailed information on this treatment method.
Dexamethasone injections - when are they necessary? Indications and precautions
Inflammatory processes in modern medicine are treated with the help of hormonal drugs, which are analogues of the hormone of the adrenal cortex. These medications include Dexamethasone injections, which allows them to be used to treat joint diseases and relieve allergic reactions.
Dexamethasone has anti-inflammatory, desensitizing (reduces sensitivity to allergens), antiallergic, antishock and antitoxic properties. The use of Dexamethasone increases the sensitivity of outer cell membrane proteins
Properties of the drug and its use
The substance Dexamethasone is a synthetic analogue of the secretion of the adrenal cortex, which is normally produced in humans, and has the following effects on the body:
- It reacts with the receptor protein, which allows the substance to penetrate directly into the nuclei of membrane cells.
- Activates a number of metabolic processes by inhibiting the enzyme phospholipase.
- Blocks mediators of inflammatory processes in the immune system.
- Inhibits the production of enzymes that affect protein breakdown, thereby improving the metabolism of bone and cartilage tissue.
- Reduces the production of leukocytes.
- Reduces vascular permeability, thereby preventing the spread of inflammatory processes.
As a result of the listed properties, the substance Dexamethasone has a powerful antiallergic, anti-inflammatory, anti-shock, and immunosuppressive effect.
Important! A distinctive positive property of the drug is that when administered intravenously, it has an almost instantaneous effect (when administered intramuscularly, after 8 hours).
Dexamethasone in ampoules is used for the systemic treatment of pathologies, in cases where local therapy and internal medication have not produced any results, or their use is impossible.
Dexamethasone regulates protein metabolism, reducing synthesis and increasing protein catabolism in muscle tissue, reducing the amount of globulins in plasma, increasing albumin synthesis in the liver and kidneys
Dexamethasone injections can be purchased abroad, or replaced with analogues, including Oftan Dexamethasone, Maxidex, Metazon, Dexazon
Most often, Dexamethasone injections are used to relieve allergic reactions, as well as to treat joint diseases. The description of the drug indicates the following conditions and diseases for which Dexamethasone is used:
- Development of acute adrenal insufficiency;
- Rheumatic pathologies;
- Intestinal diseases of unknown nature;
- Shock conditions;
- Acute forms of thrombocytopenia, hemolytic anemia, severe types of diseases of an infectious nature;
- Skin pathologies: eczema, psoriasis, dermatitis;
- Bursitis, humeroscapular periarthritis, osteoarthritis, osteochondrosis;
- Acute laryngotracheitis in children;
- Multiple sclerosis;
- Swelling of the brain due to traumatic brain injuries, meningitis, tumors, hemorrhages, radiation injuries, neurosurgical interventions, encephalitis.
Note! Dexamethasone injections have a powerful anti-inflammatory and antiallergic effect, which is 35 times more effective than the use of cortisone.
Dexamethasone injections are used in the development of acute and emergency conditions, when human life depends on the effectiveness and speed of action of the drug. The drug is usually used for a short course, taking into account vital indications.
How to use Dexamethasone injections
Dexamethasone instructions indicate that injections can be used starting from the first year of life, not only intramuscularly, but also intravenously. Determination of the dose depends on the form and severity of the disease, the presence and manifestations of side effects, and the age of the patient.
For adults, Dexamethasone can be administered in amounts from 4 mg to 20 mg, while the maximum daily dose should not exceed 80 ml, i.e. The drug is administered three to four times a day. In the event of acute, dangerous situations, the daily dosage can be increased with the consent and under the supervision of a physician.
In the form of injections, Dexamethasone is usually used for no more than 3-4 days, and if it is necessary to continue therapy, they switch to taking the drug in tablet form.
When the expected effect occurs, the dosage of the drug begins to be gradually reduced to a maintenance dose, and discontinuation of the drug is prescribed by the attending physician.
Important! For intravenous and intramuscular use, rapid administration of Dexamethasone in a large dose should not be allowed, because this can lead to heart complications.
For cerebral edema, the dosage of the drug in the initial stage of treatment should be no more than 16 mg. After this, 5 mg of the drug is administered intramuscularly or intravenously every 6 hours until a positive effect occurs.
Dexamethasone injection, 4 mg/ml, is used for acute and emergency conditions in which parenteral administration is vital. The drug is intended for short-term use for health reasons
Dexamethasone is administered to children intramuscularly. The dosage is determined according to the child’s weight - 0.2-0.4 mg per day per kilogram of weight. When treating children, treatment with the drug should not be prolonged, and the dosage should be kept to a minimum depending on the nature and severity of the disease.
Dexamethasone should be used with extreme caution during pregnancy, because active forms of the drug are able to penetrate through any barriers. The medicine can have a negative effect on the fetus and cause complications both in the fetus and in the subsequently born child. Therefore, the doctor decides whether the drug can be used during pregnancy, because this is advisable only when there is a threat to the mother’s life.
Treatment of joint diseases
When therapy for joint diseases using non-steroidal drugs does not bring the expected effect, doctors are forced to use Dexamethasone injections.
The use of Dexamethasone is permissible in the following conditions:
- Rheumatoid arthritis;
- Bursitis;
- Polyarthritis;
- Ankylosing spondylitis;
- Lupus;
- Synovitis;
- Scleroderma with articular lesions;
- Still's disease;
- Joint syndrome in psoriasis.
Note! To eliminate inflammatory processes in the joints, Dexamethasone injections can in some cases be injected directly into the joint capsule. However, long-term use inside joints is unacceptable, because may cause tendon rupture.
The medicine can be administered to the joint area no more than once per course. The drug can be re-administered in this way only after 3-4 months, i.e. per year, the use of intra-articular Dexamethasone should not exceed three to four times. Exceeding this norm can cause destruction of cartilage tissue.
The intra-articular dosage can vary from 0.4 to 4 mg depending on the patient's age, weight, size of the shoulder joint and severity of the pathology.
The drug is used for diseases requiring the administration of a fast-acting glucocorticosteroid, as well as in cases where oral administration of the drug is impossible
Treatment of allergic diseases
If allergies are accompanied by severe inflammatory processes, then conventional antihistamines will not be able to relieve this condition. In these cases, Dexamethasone is used, which is a derivative of prednisolone, which reduces the manifestation of allergic symptoms.
When are injections used:
- Hives;
- Dermatitis, eczema and other skin allergic manifestations;
- Inflammatory allergic reactions on the nasal mucosa;
- Quincke's edema;
- Angioedema and anaphylactic shock.
The description of the use of injections indicates that for allergies it is advisable to use injections in conjunction with oral medications. Usually, injections are given only on the first day of therapy - 4-8 mg intravenously. Next, tablets are prescribed for 7-8 days.
Side effects and contraindications
If there are serious complications and the risk of developing severe conditions, the main contraindication to the use of Dexamethasone is the presence of individual intolerance of the patient to the components of the drug.
For chronic pathologies and the use of the drug as prophylaxis, the following contraindications for use are taken into account:
Development of immunodeficiency (acquired and congenital);
- Severe form of osteoporosis;
- Esophagitis;
- Diabetes;
- Joint fractures;
- Infectious diseases of viral, fungal and bacterial nature in the active phase;
- Acute form of tuberculosis;
- Peptic ulcer;
- Myocardial infarction;
- Internal bleeding;
- Mental disorders.
The advisability of using Dexamethasone in the presence of contraindications should be taken into account in each individual case separately. In some cases, the use of the drug for any contraindication may lead to the development of side effects.
Use during pregnancy is allowed if the expected effect of therapy outweighs the potential risk to the fetus. Breastfeeding should be stopped during treatment. Infants born to mothers who received significant doses of corticosteroids during pregnancy should be closely monitored for signs of adrenal hypofunction.
Dexamethasone has a certain effect on the body, which can cause side effects:
- It has a depressing effect on the immune system, which increases the risk of tumors and the development of severe infectious diseases;
- Prevents healthy bone formation because inhibits calcium absorption;
- Redistributes deposits of fat cells, which causes fat tissue to be deposited on the torso;
- Retains sodium ions and water in the kidneys, which interferes with the removal of adrenocorticotropic hormone from the body.
These properties of the drug can cause negative side reactions:
- Arterial hypertension;
- Decrease in the level of monocytes and lymphocytes;
- Insomnia, mental disorders, hallucinations, depression;
- Stomach ulcer, nausea, vomiting, internal bleeding, hiccups, pancreatitis;
- Slow healing of wounds, erythema, itching, bruising, increased sweating;
- Development of impotence;
- Allergic dermatitis, urticaria, rash;
- Heart pathologies, heart failure;
- Encephalopathy;
- Sleep disorders, convulsions, dizziness;
- Adrenal atrophy;
- Swelling of the optic disc;
- Weight gain, menstrual irregularities, growth problems in children;
- Osteoporosis, muscle weakness, damage to articular cartilage, tendon rupture;
- Glaucoma, increased intraocular pressure, cataracts, exacerbations of infectious processes in the eyes.
At the injection site, pain and local symptoms may occur - scarring, atrophy of the skin.
Negative consequences can occur if the course of therapy is abruptly completed without medical consent. In such cases, the development of arterial hypertension, adrenal insufficiency, and sometimes death was observed.
Advantages and disadvantages
Reviews from doctors about the use of Dexamethasone indicate that the danger of hormonal drugs is somewhat exaggerated, and their use is very effective in the treatment of allergic conditions, cerebral edema, and joint lesions.
The main advantages of the drug are:
- Wide spectrum of action;
- Low price;
- Pronounced positive and rapid effect;
- Possibility of using the drug in complex therapy.
The disadvantages of the drug include:
- Limited use during pregnancy;
- The need for monitoring during the period of use of the medicine;
- Large list of side effects;
- The need to select the lowest possible dosage.
To avoid the negative effects of the drug, it is enough to take into account the presence or absence of contraindications, and select the dosage taking into account the patient’s age, weight, and test results.
Source: http://simptom-lechenie.ru/ukoly-deksametazon-primenenie-dozirovka-protivopokazaniya.html
When is Fukortsin solution used?
Fukortsin solution (another name is Castellani liquid) is a medicine that has antifungal and antiseptic effects.
Description of the drug
"Fukortsin" contains:
The drug is produced in the form of an aqueous or alcoholic solution of bright crimson color. There is also a colorless solution of “Fukortsin”, but since it does not contain fuchsin, which has a good antifungal effect, this type of drug will be ineffective in the treatment of fungal diseases.
Indications for use
The drug is intended for external use only. Use the solution for fungal infections, cracks, abrasions, and skin erosion. In addition to the antimicrobial effect, the product has a good drying effect, which is why Fukortsin is also used for stomatitis, diaper rash, and chickenpox.
The drug is applied to the affected areas pointwise with a swab or cotton swab. Treat the skin 2 to 5 times a day. After treatment, it is recommended to lubricate the dried areas with a nourishing cream.
How to wash Fukortsin from skin?
The disadvantage of the product is the persistent staining of the skin, just like after using a solution of brilliant green (brilliant green). You can wait until Fukortsin comes off the skin gradually, or you can try to speed up this process. There are several effective ways to help get rid of unwanted traces of the drug:
- Apply a little baby cream to a cotton pad and wipe the stained area of skin with it.
- Prepare a soap solution (it is better to choose laundry soap) and treat the skin with it.
- Buy ready-made vitamin C powder at the pharmacy, dissolve it in warm water and wash off “Fukortsin”.
- Salicylic alcohol or hydrogen peroxide can also cleanse the skin.
Contraindications to the use of the drug
Fukortsin solution is contraindicated for chronic dermatoses, any manifestations of allergies to this product, and sensitive skin. The drug is not used during pregnancy and lactation.
Side effects
Immediately after applying the solution, a short-term burning sensation and pain may appear, but this does not require discontinuation of the drug. Allergic reactions and dermatitis may begin. It is also possible for the body to become addicted, as a result of which the therapeutic effect of Fukortsin is reduced. This product should not be used on large areas of the skin, since the phenol contained in the composition can provoke poisoning of the body, the symptoms of which will be dizziness, weakness, respiratory distress, and a sharp change in blood pressure.
special instructions
It is not recommended to use the product in combination with other medications without a doctor's recommendation. Fukortsin solution is not used for children under 12 years of age. The drug is good for two years if stored in a dark place at an air temperature of 8-15 ºС.
"Fukortsin" is an effective remedy that should be in every first aid kit. However, it is recommended to use it only on the advice of a specialist.
Source: http://www.syl.ru/article/134539/kogda-primenyayut-rastvor-fukortsin
Superphosphate: characteristics, when and on what soils to use, preparation of solution
The mineral fertilizer obtained as a result of the decomposition of natural phosphates is called superphosphate (CaH2PO4)2 x H2O + 2CaSO4 x 2H2O.
The main component of the formula is phosphorus, as reflected in the name. It can be contained in a given fat from 20 to 50% of the total volume. It is very important that phosphorus oxide (P2O5) is present in this compound in a water-soluble form. This property allows the main component to be delivered to the roots of plants much faster in order to ensure its complete nutrition. This macronutrient has a number of useful and vital properties:
- Helps the plant enter the fruiting period faster;
- Improves the taste of fruits and berries;
- Slows down the aging of plants;
- Positively affects the development of the root system and tubers;
- It is an important component for plant nutrition.
When is superphosphate used?
This fertilizer has a long aftereffect. If you use it in large quantities, it will work on the principle of a multi-day bird feeder - the chicken pecks grain from it, and it is added and added until it runs out.
The same goes for phosphorus - plants take it from the soil as much as they need at a given stage, not a drop more. And this “feeder” can work for several years until supplies run out.
Experienced gardeners calculate in advance the amount of this fertilizer and its duration of action, and add new portions when the period ends. And it will be useful for beginners to know what signs may indicate the need to use superphosphate. If the leaves of plants in the garden become dark green, or even blue, or have a rusty tint, then all this indicates a lack of phosphorus. Sometimes only the reverse side of the leaf changes color, becoming purple. Often such signs appear during a sudden cold snap, or when seedlings harden. The fact is that at low temperatures, the roots do not absorb phosphorus well, and when it increases, the situation should normalize, and the leaves should acquire a green color. If this does not happen, the plants are fed with superphosphate.
On what soils should I use it?
Superphosphate is used on various types of soil. Phosphorus from this fertilizer is not fixed in the soil-absorbing complex, and plants can receive it in the required volume.
This fertilizer is especially effective for alkaline and neutral reactions of fertile soil. But when using it on acidic soils, problems may arise.
Manufacturers producing inexpensive fertilizers do not use pure raw materials for superphosphates. This does not affect the quality of the action of this agrochemical on any type of soil except acidic. In this case, it is necessary to use high-quality superphosphate, since during an acidic reaction it will not transform into iron and aluminum phosphates, which are not available for plant nutrition.
If there are noticeable signs of phosphorus deficiency, it is best to use the more expensive soluble potassium and sodium monophosphates. If you plan preventive feeding, then you don’t have to stand on ceremony and use any type of superphosphate. Then next year you won’t have to feed vegetables and fruits with this element.
Instructions for use
Application
Simple superphosphate is applied to the soil both in spring and autumn. The application rates are the same, regardless of the season – g/m² for cultivated lands, g/m² – for those already participating in crop rotation. These doses are recommended for continuous application.
When feeding fruit trees when planting, add about 500 g per hole under each one. If fertilizer is applied to a growing tree, it is recommended to use it after flowering, per one trunk circle.
In protected soil, the proportion – g/m² must be observed. Superphosphate is applied during digging along with potash and nitrogen fertilizers.
For tomatoes and potatoes, with continuous application, you need to take about 20 g/m².
Use with other fertilizers
Simple superphosphate can be used together with nitrogen fertilizers. Double and granular can be used simultaneously with potash fertilizers.
But together with ammonium nitrate, chalk and urea, in accordance with the official instructions for use, plants cannot be fertilized with this agrochemical. It is necessary to wait at least a week between their application.
Types of superphosphates
To expand the scope of application, several types of this fertilizer have been developed:
- Simple (monophosphate). Gray powder, if the recommended humidity level is observed, almost does not caking. Contains up to 20% phosphorus oxide (P2O5). Has limited effectiveness compared to newer types. But you can buy it much cheaper, which is why it is still very popular in industrial farming.
- Granular superphosphate (Ca(H2PO4)2-H2O + H3PO4+2 CaS04). It is obtained from simple material by moistening the fraction and rolling it into granules using an industrial method. This is done for ease of use. The content of phosphorus oxide in this fertilizer reaches 50%, and calcium sulfate – 30%. It is a very valuable fertilizer for cruciferous crops.
- Double.Ca(H2PO4)2H2O. Contains calcium monophosphate, highly soluble in water. It does not go into a liquid state well. Double superphosphate contains few ballast substances, which makes its use economical.
- Ammoniated (NH4H2PO4+ Ca (H2PO4)2 x H2O + CaSO4+ H3PO4). Contains a large amount of sulfur (12%) and potassium sulfate (40-55%). It dissolves well in water. Used for oilseeds and cruciferous crops that require sulfur.
There are also many other types of superphosphates, for example, magnesium, boron, molybdenum, which provide plants not only with phosphorus, but also with various microelements.
Superphosphate extract
Phosphorus is difficult to dissolve in water. But in liquid form it penetrates faster to the roots of plants. Gardeners have come up with a simple and affordable way to transfer this substance from one state of aggregation to another.
To dissolve superphosphate in water, it is necessary to ensure a high reaction temperature. To do this, the granules are poured with boiling water. Phosphorus retains its beneficial properties, while transforming into an easily digestible dispersed form. To prepare the suspension, the container with the solution must be placed in a warm place and stirred as often as possible. Then complete dissolution will occur quickly, in about a day. Externally, the resulting suspension looks like cow's milk with a high percentage of fat content.
The recommended ratio is 20 tablespoons per 3 liters. water. This is a working solution, which, in turn, is used to prepare the main fertilizer. At 10 l. add 150 ml of water. working solution (superphosphate suspension), 20 nitrogen fertilizer and 0.5 liters of wood ash. Nitrogen fertilizer must be used as a component of the irrigation solution, since phosphorus without it is poorly absorbed by plants.
When dissolving superphosphate in water, you should not be too zealous in trying to transform it into a completely liquid state of aggregation. This is impossible. But it is quite possible to achieve the grinding of phosphorus granules to the smallest particle size.
Phosphorus-nitrogen fertilizer is used in the spring, for root feeding, since during the period of active growth, plants are in dire need of nitrogen, which easily passes from the soil to the roots. Phosphorus comes from the soil gradually, and acts for several months, and even several years. Even in an easily accessible form, this chemical element is not immediately absorbed in full. Superphosphate extract is an ideal fertilizer for garden and vegetable crops with a long-lasting aftereffect.
Another way to dissolve superphosphate in water is to use live biobacteria. To do this, the agrochemical is composted with various solutions of phytosporins, with Humate, for example. After completion of the process, the resulting mixture is diluted in water at room temperature and, stirring, kept for 24 hours. After this, it is possible to use this solution for root and foliar feeding of various garden and vegetable plants at the root.
Application of superphosphate for private plants
Potato
This fertilizer is quite universal, but the greatest effect from its use should be expected in the garden. It can be applied to almost all crops, but potatoes will be especially grateful for phosphorus fertilizing.
Superphosphate can be used for spring application to each hole, about 3-4 g. For this type of use, a granular chemical will be very convenient. It allows you to more accurately dose the norm for each bush.
Since the most valuable part of potatoes is the tubers, to increase productivity it is necessary to strengthen the root system of the plant. Phosphorus is the main nutritional element responsible for its qualitative development and regeneration.
If the entire area is fertilized, then about 20 g of superphosphate is taken per square meter. This dosage is applicable for most vegetable crops.
Tomatoes
Phosphorites are added during planting of nightshades, about 20 g per plant. There is no need to deepen the fertilizer; adequate nutrition for the tomato will be provided if the fertilizer is evenly placed under a loose layer of soil at the level of the plant roots. Tomato uses more than 95% of phosphorus for fruit formation. Therefore, the use of superphosphate is not limited to spring feeding. It must also be applied during the flowering period of tomatoes.
If the fertilizer contains a lot of potassium superphosphate, then it is excellent for tomatoes, which “love” this chemical element and respond to its use with sweeter fruits.
Mature plants with a well-developed root system absorb nutrients much better. Young people, on the contrary, consume little phosphorus. Therefore, in order to save money, when planting seedlings in the ground, they are fed with granular superphosphate, which is better absorbed, and when feeding adult plants, a simple form of this fertilizer can be used.
Source: http://udobreniya.info/promyshlennye/superfosfat/
When to use
When you want to get rid of some disease, all means are good. Along with the doctor’s recommendations for medication treatment, you can, after consulting with him, use the remedies recommended by traditional medicine.
In folk medicine there are many means that can speed up recovery. For example, some people benefit from treatment with mustard.
Treatment with mustard can be used for diseases such as rheumatism, gout, neuralgia, migraine. Mustard will also help you get rid of runny nose, colds, bronchopulmonary diseases, hiccups and will return lost appetite.
For treatment, you can use mustard seeds, mustard powder, or use mustard plasters, which are sold in pharmacies.
To get rid of a runny nose or cold, use mustard powder. For a runny nose, foot baths with mustard powder help well, and for a cold, mustard powder is poured into socks and walked like this for a while. Then the socks are removed, the feet are washed to remove mustard and clean, warm socks are put on again.
Mustard seeds can help with pulmonary tuberculosis (you need to swallow a pinch of seeds several times a day) and with loss of appetite (you need to eat 30 seeds a day).
Mustard will also help those who want to get rid of freckles. To do this, you need to prepare a decoction of white lily flowers, dilute mustard flour with honey and apply it to problem areas on your skin. The whitening effect is very good.
When using mustard, do not forget that any product has contraindications, and therefore, before starting use, still consult a doctor.
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Inflammatory processes in modern medicine are treated with the help of hormonal drugs, which are analogues of the hormone of the adrenal cortex. These medications include Dexamethasone injections, which allows them to be used to treat joint diseases and relieve allergic reactions.
Dexamethasone has anti-inflammatory, desensitizing (reduces sensitivity to allergens), antiallergic, antishock and antitoxic properties. The use of Dexamethasone increases the sensitivity of outer cell membrane proteins
The substance Dexamethasone is a synthetic analogue of the secretion of the adrenal cortex, which is normally produced in humans, and has the following effects on the body:
It reacts with the receptor protein, which allows the substance to penetrate directly into the nuclei of membrane cells. Activates a number of metabolic processes by inhibiting the enzyme phospholipase. Blocks mediators of inflammatory processes in the immune system. Inhibits the production of enzymes that affect protein breakdown, thereby improving the metabolism of bone and cartilage tissue. Reduces the production of leukocytes. Reduces vascular permeability, thereby preventing the spread of inflammatory processes.
As a result of the listed properties, the substance Dexamethasone has a powerful antiallergic, anti-inflammatory, anti-shock, and immunosuppressive effect.
Important! A distinctive positive property of the drug is that when administered intravenously, it has an almost instantaneous effect (when administered intramuscularly, after 8 hours).
Dexamethasone in ampoules is used for the systemic treatment of pathologies, in cases where local therapy and internal medication have not produced any results, or their use is impossible.
Dexamethasone regulates protein metabolism, reducing synthesis and increasing protein catabolism in muscle tissue, reducing the amount of globulins in plasma, increasing albumin synthesis in the liver and kidneys
Dexamethasone injections can be purchased abroad, or replaced with analogues, including Oftan Dexamethasone, Maxidex, Metazon, Dexazon
Development of acute adrenal insufficiency; Rheumatic pathologies; Intestinal diseases of unknown nature; Shock conditions; Acute forms of thrombocytopenia, hemolytic anemia, severe types of diseases of an infectious nature; Skin pathologies: eczema, psoriasis, dermatitis; Bursitis, humeroscapular periarthritis, osteoarthritis, osteochondrosis; Acute laryngotracheitis in children; Multiple sclerosis; Swelling of the brain due to traumatic brain injuries, meningitis, tumors, hemorrhages, radiation injuries, neurosurgical interventions, encephalitis.
Note! Dexamethasone injections have a powerful anti-inflammatory and antiallergic effect, which is 35 times more effective than the use of cortisone.
Dexamethasone injections are used in the development of acute and emergency conditions, when human life depends on the effectiveness and speed of action of the drug. The drug is usually used for a short course, taking into account vital indications.
Dexamethasone instructions indicate that injections can be used starting from the first year of life, not only intramuscularly, but also intravenously. Determination of the dose depends on the form and severity of the disease, the presence and manifestations of side effects, and the age of the patient.
For adults, Dexamethasone can be administered in amounts from 4 mg to 20 mg, while the maximum daily dose should not exceed 80 ml, i.e. The drug is administered three to four times a day. In the event of acute, dangerous situations, the daily dosage can be increased with the consent and under the supervision of a physician.
In the form of injections, Dexamethasone is usually used for no more than 3-4 days, and if it is necessary to continue therapy, they switch to taking the drug in tablet form.
When the expected effect occurs, the dosage of the drug begins to be gradually reduced to a maintenance dose, and discontinuation of the drug is prescribed by the attending physician.
Important! For intravenous and intramuscular use, rapid administration of Dexamethasone in a large dose should not be allowed, because this can lead to heart complications.
For cerebral edema, the dosage of the drug in the initial stage of treatment should be no more than 16 mg. After this, 5 mg of the drug is administered intramuscularly or intravenously every 6 hours until a positive effect occurs.
Dexamethasone injection, 4 mg/ml, is used for acute and emergency conditions in which parenteral administration is vital. The drug is intended for short-term use for health reasons
Dexamethasone is administered to children intramuscularly. The dosage is determined according to the child’s weight - 0.2-0.4 mg per day per kilogram of weight. When treating children, treatment with the drug should not be prolonged, and the dosage should be kept to a minimum depending on the nature and severity of the disease.
Dexamethasone should be used with extreme caution during pregnancy, because active forms of the drug are able to penetrate through any barriers. The medicine can have a negative effect on the fetus and cause complications both in the fetus and in the subsequently born child. Therefore, the doctor decides whether the drug can be used during pregnancy, because this is advisable only when there is a threat to the mother’s life.
When therapy for joint diseases using non-steroidal drugs does not bring the expected effect, doctors are forced to use Dexamethasone injections.
The use of Dexamethasone is permissible in the following conditions:
Rheumatoid arthritis; Bursitis; Polyarthritis; Ankylosing spondylitis; Lupus; Synovitis; Scleroderma with articular lesions; Still's disease; Joint syndrome in psoriasis.
Note! To eliminate inflammatory processes in the joints, Dexamethasone injections can in some cases be injected directly into the joint capsule. However, long-term use inside joints is unacceptable, because may cause tendon rupture.
The medicine can be administered to the joint area no more than once per course. The drug can be re-administered in this way only after 3-4 months, i.e. per year, the use of intra-articular Dexamethasone should not exceed three to four times. Exceeding this norm can cause destruction of cartilage tissue.
The intra-articular dosage can vary from 0.4 to 4 mg depending on the patient's age, weight, size of the shoulder joint and severity of the pathology.
The drug is used for diseases requiring the administration of a fast-acting glucocorticosteroid, as well as in cases where oral administration of the drug is impossible
If allergies are accompanied by severe inflammatory processes, then conventional antihistamines will not be able to relieve this condition. In these cases, Dexamethasone is used, which is a derivative of prednisolone, which reduces the manifestation of allergic symptoms.
When are injections used:
Hives; Dermatitis, eczema and other skin allergic manifestations; Inflammatory allergic reactions on the nasal mucosa; Quincke's edema; Angioedema and anaphylactic shock.
The description of the use of injections indicates that for allergies it is advisable to use injections in conjunction with oral medications. Usually, injections are given only on the first day of therapy - 4-8 mg intravenously. Next, tablets are prescribed for 7-8 days.
If there are serious complications and the risk of developing severe conditions, the main contraindication to the use of Dexamethasone is the presence of individual intolerance of the patient to the components of the drug.
For chronic pathologies and the use of the drug as prophylaxis, the following contraindications for use are taken into account:
Development of immunodeficiency (acquired and congenital);
Severe form of osteoporosis; Esophagitis; Diabetes; Joint fractures; Infectious diseases of viral, fungal and bacterial nature in the active phase; Acute form of tuberculosis; Peptic ulcer; Myocardial infarction; Internal bleeding; Mental disorders.
The advisability of using Dexamethasone in the presence of contraindications should be taken into account in each individual case separately. In some cases, the use of the drug for any contraindication may lead to the development of side effects.
Use during pregnancy is allowed if the expected effect of therapy outweighs the potential risk to the fetus. Breastfeeding should be stopped during treatment. Infants born to mothers who received significant doses of corticosteroids during pregnancy should be closely monitored for signs of adrenal hypofunction.
Dexamethasone has a certain effect on the body, which can cause side effects:
It has a depressing effect on the immune system, which increases the risk of tumors and the development of severe infectious diseases; Prevents healthy bone formation because inhibits calcium absorption; Redistributes deposits of fat cells, which causes fat tissue to be deposited on the torso; Retains sodium ions and water in the kidneys, which interferes with the removal of adrenocorticotropic hormone from the body.
These properties of the drug can cause negative side reactions:
Arterial hypertension; Decrease in the level of monocytes and lymphocytes; Insomnia, mental disorders, hallucinations, depression; Stomach ulcer, nausea, vomiting, internal bleeding, hiccups, pancreatitis; Slow healing of wounds, erythema, itching, bruising, increased sweating; Development of impotence; Allergic dermatitis, urticaria, rash; Heart pathologies, heart failure; Encephalopathy; Sleep disorders, convulsions, dizziness; Adrenal atrophy; Swelling of the optic disc; Weight gain, menstrual irregularities, growth problems in children; Osteoporosis, muscle weakness, damage to articular cartilage, tendon rupture; Glaucoma, increased intraocular pressure, cataracts, exacerbations of infectious processes in the eyes.
At the injection site, pain and local symptoms may occur - scarring, atrophy of the skin.
Note! You can reduce the negative impact of the drug by reducing the dosage, but in some cases only stopping the drug helps. In any case, if you feel unwell, you should immediately inform your doctor.
Negative consequences can occur if the course of therapy is abruptly completed without medical consent. In such cases, the development of arterial hypertension, adrenal insufficiency, and sometimes death was observed.
Reviews from doctors about the use of Dexamethasone indicate that the danger of hormonal drugs is somewhat exaggerated, and their use is very effective in the treatment of allergic conditions, cerebral edema, and joint lesions.
The main advantages of the drug are:
Wide spectrum of action; Low price; Pronounced positive and rapid effect; Possibility of using the drug in complex therapy.
The disadvantages of the drug include:
Limited use during pregnancy; The need for monitoring during the period of use of the medicine; Large list of side effects; The need to select the lowest possible dosage.
To avoid the negative effects of the drug, it is enough to take into account the presence or absence of contraindications, and select the dosage taking into account the patient’s age, weight, and test results.
What are we used to using for a runny nose? Vasoconstrictor drops, which have no therapeutic effect at all, and moisturizing saline solutions - that’s all the variety. At the same time, on the pharmaceutical market there is a completely unique complex spray Rinofluimucil, which alleviates rhinitis and rhinosinusitis, regardless of their origin.
>> The site presents an extensive selection of medications for the treatment of sinusitis and other nasal diseases. Enjoy it for your health! <<
The drug, which is produced by the Italian company Zambon, contains two active ingredients that enhance each other’s effects: acetylcysteine and tuaminoheptane.
Acythelicysteine is a synthetic substance whose structure contains a free sulfhydryl group. Thanks to its presence, the drug has a pronounced mucolytic effect, breaking the disulfide bonds that “hold together” acidic mucopolysaccharides. Namely, they are the main link that ensures the thick, viscous consistency of sputum and nasal mucus. In addition, acetylcysteine reduces the inflammatory process and even binds free radicals, providing an antioxidant effect.
Tuaminoheptane is a drug that is used only in combination with other drugs. It has vasoconstrictor properties, and its peculiarity is its short-term action. Therefore, tuaminoheptane has not found use as a vasoconstrictor drug to facilitate nasal breathing.
Tuaminoheptane works well as a component of the complex drug Rinofluimucil. Due to the fact that it provides a rapid, albeit rather short-term, vasoconstriction, the second substance of the combination, acetylcysteine, can penetrate into the deepest parts of the nasal cavity and effectively thin out thick mucus.
Rinofluimucil is prescribed for the most common diseases of the nasal mucosa and paranasal sinuses, including those accompanied by the release of thick purulent discharge.
Among the pathologies for which Rinofluimucil nasal spray can be used:
acute, as well as subacute rhinitis - inflammation of the nasal mucosa. It is advisable to use Rinofluimucil for purulent discharge that requires liquefaction; chronic rhinitis; sinusitis, that is, inflammation of the paranasal sinuses. As a rule, we are talking about sinusitis - both acute and chronic sinusitis. vasomotor rhinitis, in which impaired nasal breathing is caused by thickening of the nasal mucosa. We emphasize that Rinofluimucil only alleviates the condition of vasomotor rhinitis, but the disease itself is usually treated surgically.
Rinofluimucil is prescribed for the most common diseases of the nasal mucosa and paranasal sinuses, including those accompanied by the release of thick purulent discharge.
Among the pathologies for which Rinofluimucil nasal spray can be used:
acute, as well as subacute rhinitis - inflammation of the nasal mucosa. It is advisable to use Rinofluimucil for purulent discharge that requires liquefaction; chronic rhinitis; sinusitis, that is, inflammation of the paranasal sinuses. As a rule, we are talking about sinusitis - both acute and chronic sinusitis. vasomotor rhinitis, in which impaired nasal breathing is caused by thickening of the nasal mucosa. We emphasize that Rinofluimucil only alleviates the condition of vasomotor rhinitis, but the disease itself is usually treated surgically.
According to the instructions for Rinofluimucil, it is intended for irrigation of the nasal cavity. The drug is a solution with a menthol odor, placed in a bottle with a spray nozzle. Preparation for using the spray is simple: just remove the cap from the bottle and sprayer, and then remove the protective cap from the latter. There is no need to calibrate it, that is, spray a “test” dosage, as in some other dosed preparations for irrigating the nose or throat. That's all the wisdom that describes how to take Rinofluimucil.
Note that Rinofluimucil is a dosed nasal spray. When it is sprayed, a strictly defined dose of the medicinal composition is released. After pressing the cap with the drug, one milliliter of solution is released, which contains:
acetylcysteine 10 mg; Tuaminoheptane sulfate 5 mg.
The average dosage for adults, regardless of the type of disease, is 2 doses of the drug (that is, two presses on the spray) in each nasal passage. Frequency of application 3-4 times a day.
For children, the spray is prescribed in a dosage half as much as for adults: one dose 3-4 times a day.
Important: the course of treatment with Rinofluimucil should not exceed seven days!
Despite the fact that tuaminoheptane sulfate is one of the little-known and rarely used adrenergic agonists, it has all the properties of drugs in this group. The drug not only constricts blood vessels, reduces swelling and hyperemia in the nasal cavity and makes breathing easier. It, like other vasoconstrictors, can cause the development of drug-induced rhinitis.
The main condition for the development of this side effect is to use the medicine for more than seven days in a row. This time is quite enough for the body to get used to the continuous flow of adrenergic agonists into the nasal cavity and “forget how” to breathe without them. Drug-induced rhinitis, or withdrawal rhinitis, which is sometimes called rebound rhinitis, is characterized by chemical damage to the nasal mucosa.
Long-term exposure to Rinofluimucil spray and its component tuaminoheptane sulfate on the mucous membrane causes not only dilation of blood vessels in it, but also changes at the cellular level. Therefore, drug-induced rhinitis is a serious consequence of improper therapy, which causes no less problems than the initial sinusitis or viral rhinitis. To prevent drug-induced damage to the nasal mucosa, the recommended course of treatment with alpha-agonists should not be exceeded.
It is safe to treat with tuaminohepatone sulfate and other vasoconstrictor drugs for no longer than seven, maximum ten days.
The instructions for use of Rinofluimul provide only one option for prescribing the drug - in the form of irrigation of the nasal cavity. However, due to the fact that the drug does not contain sugars, it can also be used for inhalation. Particles with a size of no more than 10 microns enter remote areas of the nasal cavity and maxillary sinuses. This should be taken into account when choosing a nebulizer for nasal inhalation.
The inhalation route of administration is characterized by the highest efficiency. The rapid and finely dispersed delivery of active substances directly to the site of inflammation allows you to reduce drug losses and achieve the highest possible concentration. Therefore, nebulizer inhalation treatment with Rinofluimucil is an excellent alternative to traditional nasal drops or spray.
Fine particles of acetylcysteine and tuaminoheptane sulfate arriving during the nebulizer administration of Rinofluimucil are evenly distributed in the nasal cavity and maxillary sinuses. Thanks to this, thick nasal secretions are removed, which accumulated in the most remote parts of the nasal cavity and in the paranasal sinuses. Reducing swelling helps to increase the size of the openings between the maxillary sinuses and the nasal cavity and facilitate the removal of secretions.
Yes, the benefits of inhaled drug administration are undeniable. But what about Rinofluimucil, which is available in only one form - a spray? How to prepare an inhalation solution when there is no solution as such at hand? In fact, everything is simple, and domestic craftsmen have long learned to solve such “problems.”
We already know that each dose of Rinofluimucil contains exactly 1 ml of solution. To obtain a solution for inhalation, you need to spray one or two doses of spray into a container (one for a child and two for an adult) and dilute them with a neutral solution. It is best to use three milliliters of sodium chloride 0.9%, and the medicine for inhalation with Rinofluimucil can be considered ready. To obtain a therapeutic effect, it is enough to carry out two inhalations per day, the course of therapy is seven days.
Inhalations with Rinofluimucil can be combined with inhalation administration of saline or antiseptic solutions. This will increase the final effectiveness of therapy.
According to the official instructions, Rinofluimucil can be used to treat all children over three years old without worry or worry. Information about the possibilities of using the drug for patients under three years of age is rather scarce: in the chapter “Special Instructions” it is dryly noted that at this age Rinofluimucil should be used with caution. Let's decipher the encoded messages that the manufacturer hid behind common phrases that are incomprehensible to mere mortals.
So, if the instructions do not explicitly say that the drug is prohibited for use in children under 3 years of age, therefore, a priori it can be used in this category of patients. Another important fact in favor of Rinofluimucil, prescribed for the treatment of young children, is that the drug, when applied topically, does not have a systemic effect. This means that it is not absorbed into the blood at all and is therefore particularly safe. But why then is the manufacturer trying to get around the rough edges and relieve itself of responsibility for prescribing Rinofluimucil to young children?
It's actually simple.
To “give the go-ahead” for the use of a drug in any “special” category of patients—be it infants, pregnant women, or patients with severe systemic disease—the manufacturer must prove the drug’s safety in clinical trials.
Studies of the use of Rinofluimucil in newborns and young children have not been conducted. That is why, despite all the facts that indicate the potential safety of the spray, the instructions contain a warning that frightens parents.
We would like to add that all nasal and throat sprays should be used with caution when treating children under one year of age. This is due to the likelihood of developing bronchospasm in response to a sudden entry of the drug solution into the nasopharynx.
In the vast majority of patients, Rinofluimucil is well tolerated. However, like any medicine, it can cause adverse events. The side effects of Rinofluimucil are quite traditional for vasoconstrictors: after its use, tachycardia, a slight increase in blood pressure, and dryness of the nasopharyngeal mucosa may develop. But as a rule, these adverse events are not dangerous and do not serve as a reason to stop treatment.
Despite the relatively high safety, there are several conditions in which Rinofluimucil is strictly contraindicated. Among them:
angle-closure glaucoma. Additional vasoconstriction as a result of the use of alpha-agonists can contribute to the deterioration of the condition and a sharp blockage of outflow from the eye. As a result, intraocular pressure quickly and significantly increases, which is fraught with atrophic changes in the optic nerve; thyrotoxicosis; hypersensitivity to acetylcysteine or tuaminoheptane sulfate.
Particular caution when prescribing Rinofluimucil should be exercised by people suffering from cardiovascular diseases: arterial hypertension, severe angina pectoris and frequent extrasystole. In such cases, the use of any vasoconstrictor should be monitored by a cardiologist.
It should be remembered that acetylcysteine can increase the likelihood of bronchospasm, so patients with bronchial asthma should monitor their condition after irrigating their nose with Rinofluimucil. If signs of bronchospasm appear, the drug is immediately discontinued.
The safety of Rinofluimucil during pregnancy and breastfeeding has not been studied. Therefore, the official instructions state that the drug is allowed only in the most extreme cases, when the benefit significantly outweighs the possible risk to the child. In practice, neither ENT doctors nor obstetricians see much sense in using Rinofluimucil, and the question of the advisability of prescribing it to pregnant women is usually not even raised.
Rinofluimucil may react with some drugs, and in particular with antidepressants. This is due to the fact that alpha-agonists (in our case, tuaminoheptane sulfate) can increase the likelihood of developing side effects characteristic of some antidepressants.
That is why Rinofluimucil should not be used simultaneously with:
MAO inhibitors (antidepressants pyrazidol and others). tricyclic antidepressants, of which amitriptyline is most often used.
The restriction on the use of Rinofluimucil with antidepressants remains until 14 days after the end of treatment for depression with MAO inhibitors and amitriptyline.
There is another limitation associated with the ability of Rinofluimucil to constrict blood vessels. Reducing the lumen of blood vessels can weaken the effect of hypotonic drugs. Therefore, hypertensive patients receiving constant treatment with antihypertensive drugs should remember this property of Rinofluimucil before starting its use.
The drug is unpretentious: it retains its properties at a temperature of 15–25°C. However, there is one nuance that it is better not to forget about. According to the instructions, the shelf life of a vial of Rinofluimucil after initial opening should not exceed 20 days. Otherwise, there is a possibility of contamination of the solution with pathogenic flora, which can lead to the development of additional inflammation in the nasal cavity.
Many buyers in times of crisis and rising exchange rates are interested in one question: are there cheaper analogues of Rinofluimucil for children and adults? Unfortunately, there is nothing to please. Domestic and even foreign enterprises producing generic drugs have not yet mastered the production of a drug containing acetylcysteine and tuaminoheptane sulfate. Rinofluimucil was and remains a unique, safe combination that makes breathing easier and truly cures a runny nose at any age.