Fluimucil nasal drops price

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Fluimucil

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Release form, composition and packaging

The solution for injection and inhalation is transparent, colorless, with a faint sulfuric odor; After opening the ampoule, a faint pink-violet tint may appear upon prolonged contact with air.

Table of contents:

Excipients: disodium edetate, sodium hydroxide, water for injection.

3 ml - dark glass ampoules (5) - plastic holders (1) - cardboard packs.

Clinical and pharmacological group

pharmachologic effect

Mucolytic drug. Liquefies mucus, increases its volume and facilitates its separation. The action of acetylcysteine ​​is associated with the ability of its sulfhydryl groups to break intra- and intermolecular disulfide bonds of acidic mucopolysaccharides of sputum, which leads to depolarization of mucoproteins and a decrease in sputum viscosity. Remains active in the presence of purulent sputum.

Increases the secretion of less viscous sialomucins by goblet cells, reduces the adhesion of bacteria to the epithelial cells of the bronchial mucosa. Stimulates mucous cells of the bronchi, the secretion of which is lysed by fibrin. It has a similar effect on the secretions formed during inflammatory diseases of the ENT organs.

It has an antioxidant effect due to the presence of an SH group that can neutralize electrophilic oxidative toxins.

Acetylcysteine ​​easily penetrates into the cell and is deacetylated to L-cysteine, from which intracellular glutathione is synthesized. Glutathione is a highly reactive tripeptide, a powerful antioxidant and cytoprotector that neutralizes endogenous and exogenous free radicals and toxins. Acetylcysteine ​​prevents exhaustion and helps increase the synthesis of intracellular glutathione, which is involved in the redox processes of cells, promoting the detoxification of harmful substances. This explains the effect of acetylcysteine ​​as an antidote for paracetamol poisoning.

Protects alpha1-antitrypsin (elastase inhibitor) from the inactivating effects of HOCl, an oxidizing agent produced by myeloperoxidase of active phagocytes. It also has an anti-inflammatory effect (by suppressing the formation of free radicals and reactive oxygen-containing substances responsible for the development of inflammation in the lung tissue).

Pharmacokinetics

When taken orally, it is well absorbed from the gastrointestinal tract. With intravenous administration of 600 mg of acetylcysteine, Cmax in plasma is 300 mmol/l.

Penetrates into the intercellular space, predominantly distributed in the liver, kidneys, lungs, and bronchial secretions. Penetrates through the placental barrier.

Vd at equilibrium is 0.34 l/kg.

Rapidly deacetylated to cysteine ​​in the liver. In the plasma, a mobile equilibrium of free acetylcysteine ​​and its metabolites (cysteine, cystine, diacetylcystine) is observed, free and bound to plasma proteins.

T1 /2 is 2 hours. It is excreted in the urine in the form of inactive metabolites (inorganic sulfates, diacetylcysteine), a small part is excreted unchanged through the intestines.

Indications for use of the drug

- diseases of the respiratory system, accompanied by impaired sputum discharge (including bronchitis, tracheitis, bronchiolitis, pneumonia, bronchiectasis, cystic fibrosis, lung abscess, pulmonary emphysema, laryngotracheitis, interstitial lung diseases, pulmonary atelectasis /due to blockage of the bronchi by mucus plug/) ;

- catarrhal and purulent otitis media, sinusitis, incl. sinusitis (to facilitate the passage of secretions);

— to remove viscous secretions from the respiratory tract in post-traumatic and postoperative conditions;

— preparation for bronchoscopy, bronchography, aspiration drainage;

- for washing abscesses, nasal passages, maxillary sinuses, middle ear, treatment of fistulas, surgical field during operations on the nasal cavity and mastoid process.

Dosage regimen

For aerosol therapy, 3-9 ml of a 10% solution is sprayed in ultrasound devices, and 6 ml of a 10% solution is sprayed in devices with a distribution valve. Duration of inhalation min; multiplicity times/day When treating acute conditions, the average duration of therapy is days; for long-term therapy of chronic conditions, the course of treatment is up to 6 months.

Due to the high safety of the drug, the frequency of administration and the relative dose can be changed by the doctor within acceptable limits, depending on the patient’s condition and the therapeutic effect. There is no need to change the adult dose when using the drug to treat children. In the case of a strong secretolytic effect, the secretion is sucked out, and the frequency of inhalations and the daily dose are reduced.

To wash the bronchial tree during therapeutic bronchoscopy, use 1-2 ampoules or more per day, depending on clinical indications.

Instill into the external auditory canal and nasal passages (1.5-3 ml) for 1 procedure.

Administer intravenously (preferably drip or slow stream over 5 minutes) or intramuscularly. Adults - 300 mg (3 ml) 1-2 times a day; children from 6 to 14 years old - 150 mg (1.5 ml) 1-2 times a day. The daily dose for children under 6 years of age is 10 mg/kg body weight; for children under 1 year of age, intravenous administration of acetylcysteine ​​is possible only for health reasons in a hospital setting. The duration of treatment should be determined based on changes in the patient's condition.

It should be taken into account that oral administration of the drug is preferable for children under 6 years of age.

High local and general tolerability of the drug allows for long courses of treatment.

For intravenous administration, the solution is further diluted with 0.9% sodium chloride solution or 5% dextrose solution in a 1:1 ratio. The duration of therapy is determined individually (no more than 10 days).

In patients over 65 years of age, the minimum effective dose is used.

Side effect

With aerosol therapy: reflex cough, respiratory tract irritation, rhinorrhea; rarely - stomatitis, bronchospasm.

With intramuscular injection: burning at the injection site, skin rash, urticaria; with long-term treatment - impaired liver and/or kidney function.

Contraindications to the use of the drug

- peptic ulcer of the stomach and duodenum in the acute phase;

- hypersensitivity to acetylcysteine.

with caution for peptic ulcers of the stomach and duodenum in remission, varicose veins of the esophagus, hemoptysis, pulmonary hemorrhage, bronchial asthma (with intravenous administration the risk of developing bronchospasm increases), diseases of the adrenal glands, liver and/or kidney failure, arterial hypertension , as well as children under 6 years of age.

For children under 1 year of age, intravenous administration of acetylcysteine ​​is possible only for health reasons in a hospital setting.

Use of the drug during pregnancy and lactation

During pregnancy, the use of Fluimucil is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.

If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped.

Use for liver dysfunction

The drug should be prescribed with caution to patients with liver disease.

Use for renal impairment

The drug should be prescribed with caution to patients with kidney disease.

special instructions

For patients with bronchial asthma and obstructive bronchitis, acetylcysteine ​​should be prescribed with caution under systematic monitoring of bronchial patency.

With a shallow intramuscular injection of the drug and in the presence of increased sensitivity, a slight and quickly passing burning sensation may appear, and therefore it is recommended to inject the drug deep into the muscle.

The Fluimucil ampoule is opened before use. An opened ampoule can be stored in the refrigerator for 24 hours, during which time the drug can only be used for inhalation.

Fluimucil solution should not come into contact with rubber and metal surfaces.

Overdose

Fluimucil ® when taken at a dose of 500 mg/kg/day does not cause signs and symptoms of overdose.

Drug interactions

The simultaneous use of Fluimucil with antitussives may increase sputum stagnation due to suppression of the cough reflex.

When used simultaneously with antibiotics, such as tetracyclines (excluding doxycycline), ampicillin, amphotericin B, they may interact with the thiol group of acetylcysteine, which leads to a decrease in the activity of both drugs, so the interval between taking acetylcysteine ​​and antibiotics should be at least 2 hours.

The simultaneous use of Fluimucil and nitroglycerin can lead to an increase in the vasodilatory effect of the latter.

Acetylcysteine ​​reduces the hepatotoxic effect of paracetamol.

Pharmaceutically incompatible with other drug solutions.

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Storage conditions and periods

The drug should be stored out of the reach of children at a temperature of 15° to 25°C. Shelf life: 5 years.

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Source: http://www.rigla.ru/shop/forms/fluimutsil/

Fluimucil nasal drops - an effective treatment for nasal diseases

This drug will help in a short time to cope with the manifestations of inflammation in various pathologies. The composition of the drops, indications for their use, as well as instructions for use will be discussed below.

Release form

The drug is available in the form:

  • granules A solution is prepared from them, intended for oral administration. Sold in cardboard packages containing 20 or 60 bags of granules;
  • effervescent tablets. A solution for oral administration is also prepared from them. A cardboard pack contains 10 or 20 tablets;
  • solution in ampoules, which is used for instillation into the nose, inhalation or injection. For rinsing the sinuses, a solution is available in a 3 ml bottle.

    • Composition and effects

    1 ampoule of Fluimucil drops contains 300 mg of acetylcysteine. As additional components: water, sodium hydroxide, disodium edetate.

    Acetylcysteine ​​helps to liquefy and remove fluid from the nasal cavity. Thanks to this, the removal of pathogenic bacteria is accelerated, which contributes to a speedy recovery.

    In addition, Fluimucil nasal spray has an antioxidant effect. The drug reduces lipid oxidation processes, blocks toxins and free radicals.

    Fluimucil drops have the following therapeutic effects:

    • anti-inflammatory;
    • relieving swelling of the nasal mucosa;
    • constriction of blood vessels, which reduces the release of fluid from the lumen of blood vessels into the nasal cavity.

    Indications and contraindications

    Fluimucil nasal drops are indicated for respiratory tract pathologies. The product will also help in case of excessively viscous secretion, which is difficult to discharge from the cavity. The medicine is also effective in cases of prolonged illness. Fluimucil for the nose is indicated for the following conditions:

    The product is indicated for use in children over 3 years of age. In infants, drops are used on the recommendation of a specialist and under his supervision.

    The instructions for use of Fluimucil state that the drug is contraindicated in the following conditions:

    • discharge from the nasal cavity with blood;
    • glaucoma;
    • pregnancy and lactation;
    • high sensitivity to the components of the drug;
    • insufficiency of liver and kidney function;
    • gastrointestinal ulcer in the acute stage;
    • bronchial asthma;
    • pulmonary hemorrhage.

    Instructions and dosage

    The instructions for Fluimucil nasal drops contain the following methods of use:

    • if the patient is over 12 years old, then the product is instilled into the nose up to 4 times a day, 3 drops in each nostril;
    • Children under 12 years of age can use no more than two drops in each nostril three times a day.

    The medicine should not be used for more than 1 week. If treatment needs to be extended, you should consult your doctor.

    To wash the sinuses and other cavities, you need to prepare a solution. To do this, mix 500 mg of Fluimucil powder in 4 ml of water for injection. For patients under 12 years of age, the amount of powder should be reduced to 250 mg. For rinsing you will need 1-2 ml of the prepared solution.

    Side effects

    The instructions for Fluimucil nasal drops list the following side effects:

    • diarrhea;
    • nose bleed;
    • bronchospasm;
    • allergic reactions;
    • nausea and vomiting;
    • heartburn;
    • noise in ears;
    • stomach discomfort;
    • pressure drop;
    • respiratory tract irritation;
    • skin itching;
    • cough;
    • tachycardia;
    • dry mucous membranes;
    • hypertension;
    • urinary retention;
    • excessive nervous excitability.

    All these adverse reactions can be avoided if you do not use the drug yourself without consulting your doctor.

    Fluimucil nasal drops are an effective remedy that will quickly help eliminate both acute and chronic manifestations of nasal diseases. A variety of release forms allows the drug to be used both in the form of nasal drops and in the form of inhalations. Moreover, the medicine is quite safe. However, it is not recommended to use it on your own, since there are still contraindications and side effects. Therefore, before use, you should consult your doctor and use the drug only in accordance with the instructions.

    Author: Vladislava Spiridonova, specialist,

    Source: http://moylor.ru/lekarstva/kapli-v-nos/fluimucil/

    Fluimucil

    Description current as of 05/16/2014

    • Latin name: Fluimucil
    • ATX code: R05CB01
    • Active ingredient: Acetylcysteine
    • Manufacturer: Zambon, Switzerland

    Compound

    1 tablet contains acetylcysteine ​​600 mg and additional substances: sodium bicarbonate, citric acid, lemon flavor, aspartame.

    1 bag of granules contains acetylcysteine ​​200 mg, excipients: beta-carotene, aspartame, sorbitol, orange flavor.

    1 ml of solution for inhalation and injection contains 100 mg of acetylcysteine, 1 ampoule contains 300 mg of acetylcysteine, additional substances: sodium hydroxide, disodium edetate, water.

    Release form

    Effervescent tablets, soluble in water, in blisters of 2 and 10 pcs.

    Granules in multilayer bags, for dissolving in water and preparing a solution.

    Solution in dark glass ampoules of 3 ml.

    pharmachologic effect

    Has a mucolytic effect. Acetylcysteine ​​breaks disulfide bonds in mucopolysaccharides of sputum, thereby ensuring its dilution and facilitating excretion. Even in the case of purulent sputum, it remains effective.

    The drug prevents the adhesion of bacteria to the epithelium of the bronchial mucosa, stimulates cells that synthesize substances that break down fibrin threads. Acetylcysteine ​​has the same effect on the secretion of the mucous membranes of the upper respiratory tract.

    The drug provides an antioxidant effect, has a cytoprotective effect and neutralizes toxins.

    Acetylcysteine ​​has an anti-inflammatory effect due to its ability to suppress the formation of free radicals that cause inflammation in the lung tissue.

    Pharmacodynamics and pharmacokinetics

    After taking the drug, the maximum concentration in the blood occurs within 1-3 hours. Bioavailability is about 10%. Penetrates into the lungs, bronchial secretions, liver and kidneys; through the placenta.

    It is excreted in the urine, the half-life is 1 hour, in case of liver cirrhosis it is 8 hours.

    Indications for use

    • difficult sputum discharge due to respiratory pathology (laryngotracheitis, tracheitis, bronchitis, pneumonia, bronchiolitis, lung abscess, emphysema, cystic fibrosis, bronchiectasis, atelectasis, caused by obstruction of the bronchi with a mucus plug);
    • otitis, sinusitis (catarrhal and purulent);
    • facilitating the release of viscous secretions from the respiratory system (post-traumatic and postoperative conditions);
    • washing of the nasal passages, middle ear, maxillary sinuses, abscesses, fistulas, treatment of the intervention zone during operations on the mastoid process or nasal cavity;
    • preparation for aspiration drainage, bronchography, bronchoscopy.

    Contraindications

    • exacerbation of stomach and duodenal ulcers;
    • individual intolerance to acetylcysteine;
    • breastfeeding period;
    • for granules - children under two years of age;
    • for effervescent tablets – children and adolescents under 18 years of age.

    Children under 2 years of age are allowed to take a solution prepared from granules under the supervision of a doctor for health reasons.

    For stomach ulcers, hemoptysis, bronchial asthma, arterial hypertension, pulmonary hemorrhage, phenylketonuria, renal and liver failure, varicose veins of the esophagus, use with caution.

    Intravenous administration of the drug to children under 1 year of age is carried out for health reasons, under the supervision of a doctor.

    Side effects

    Digestive system: nausea, vomiting, heartburn, heaviness in the stomach, diarrhea.

    Allergic reactions: cases of bronchospasm, urticaria, itching are possible.

    Other symptoms may very rarely include: tinnitus, nosebleeds, collapse.

    When used in the form of an aerosol: irritating effect on the respiratory tract, reflex cough, rhinorrhea, rarely - bronchospasm.

    Intramuscular administration can lead to urticaria, burning at the injection site, and in case of long-term use, impaired renal and liver function.

    Instructions for use of Fluimucil (Method and dosage)

    For adults, effervescent tablets are used orally - 1 tablet (600 mg) per day once, pre-dissolved in a third of a glass of water.

    The granules are used by both adults and children, dissolved in water (a third of a glass).

    • children over 6 years of age and adults – 600 mg per day in 3 divided doses;
    • for children under 200 mg twice daily;
    • 1 - 2 years - 100 mg twice a day.

    For newborns, the drug is used under the supervision of a specialist in vital indications, observing a dose of 10 mg/kg of the child’s weight. Children in the first year of life are given syrup to drink from a spoon or bottle.

    The average course of treatment is 5-10 days for acute cases, and several months for chronic cases.

    For inhalation in physiotherapy, a 10% solution is used in an amount of 3-9 ml. Duration of inhalations is up to 20 minutes, 2 to 4 times a day.

    If the drug is used during bronchoscopy for medicinal purposes, use 1-2 ampoules to wash the bronchi.

    A dose of up to 300 mg is instilled into the external auditory canal at a time.

    For use in rhinitis, there is a special form - nasal drops.

    When administered intravenously (drip or slow stream) or intramuscularly, doses are determined as follows:

    • adults mg up to 2 times a day;
    • children 6-14 years old, 150 mg 2 times a day;
    • children under 6 years old - at the rate of 10 mg/kg.

    Acetylcysteine ​​is administered to children under 1 year of age in hospital settings for health reasons.

    The duration of treatment depends on the patient's condition.

    When used for cough in children under 6 years of age, preference should be given to oral administration.

    For intravenous administration, the drug is diluted with 0.9% sodium chloride solution in equal quantities. The duration of treatment in case of intravenous administration should not exceed 10 days.

    In elderly patients, the instructions for Fluimucil indicate the need to use the minimum effective doses.

    Overdose

    Taking the drug in an amount of 0.5 g. per kg of body weight per day does not cause an overdose.

    Interaction

    Combined use with cough suppressants that suppress the cough reflex contributes to stagnation of sputum.

    The use of tetracyclines (except doxycycline), amphotericin and ampicillin leads to a decrease in the effect of both antibiotics and acetylcysteine, so the break between taking these groups of drugs should be at least 2 hours.

    The antiplatelet and vasodilating effect of nitroglycerin is enhanced when taken simultaneously with Fluimucil.

    Pharmaceutically incompatible with other medicinal solutions.

    Terms of sale

    Over the counter - tablets and granules.

    According to the recipe - solution.

    Storage conditions

    Keep away from children, storage temperature no more than 25°C.

    Best before date

    special instructions

    Fluimucil is prescribed to patients with bronchial asthma and obstructive bronchitis with caution and under constant monitoring of bronchial patency.

    It is not recommended for use in patients with phenylketonuria, since the drug contains aspartame.

    For dissolution, use only glass containers and avoid contact with rubber and metal surfaces.

    The smell of sulfur that appears when opening a bag of granules is a normal odor characteristic of the active substance.

    Analogs

    Fluimucil or ACC - which is better?

    Both drugs contain the same active ingredient. They differ only in manufacturer and price, and even then only slightly. For example, 6 sachets of ACC with a dose of 600 mg cost 127 rubles, and Fluimucil costs 10 tablets. 174 rub. Therefore, the buyer must decide for himself which drug to choose.

    For children

    Use according to indications according to the instructions for the drug.

    During pregnancy and lactation

    If there is a need to use a medicine during pregnancy, you need to evaluate the balance of benefit to the mother and risk to the fetus.

    During breastfeeding, if there is a need to use the drug, feeding should be stopped.

    Reviews of Fluimucil

    Fluimucil is quite popular for use against coughs. Numerous reviews are usually positive. There are good results from use against cough - Fluimucil is quite effective in both adults and children. On forums for young mothers, when asked to recommend a good cough syrup, many people remember Fluimucil. Perhaps the only drawback of using the drug is the formation of a large amount of sputum.

    Nasal drops are also popular - there are many positive reviews when used in case of rhinitis.

    Fluimucil price, where to buy

    In Russia, the average price of Fluimucil tablets is 200 rubles. In Moscow, a package of 10 tablets with a dose of 600 mg costs 174 rubles, and granules can be bought for 186 rubles. for 20 packages.

    • Online pharmacies in Russia Russia
    • Online pharmacies in Ukraine Ukraine
    • Online pharmacies in Kazakhstan Kazakhstan

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    BIOSPHERE

    Inna: Usually, insomnia occurs for me due to some kind of experience and when you lie down, it’s not.

    Olesya: I tried glycine forte, which is more expensive in the price category, but the dosage is the same.

    Andrey: Not a word is said about choosing the size of stockings according to a person’s parameters: height, leg size, etc.

    Olga: For coxarthrosis of the 2nd degree, I have been injecting for 4 years at the rate (after 6 months), there is no improvement.

    All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

    The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

    Source: http://medside.ru/fluimutsil

    How to put Fluimucil drops into your nose?

    Everyone knows that a stuffy nose can reduce the quality of life and cause a number of undesirable consequences. In addition to the loss of smell, the patient may develop sinusitis, acute rhinitis, inflammation of the respiratory tract and other ailments that will affect the patient’s health. When fighting such diseases, comprehensive treatment is necessary.

    When treating a runny nose and cough, many patients use a variety of medications. But not many people know that there is an effective drug that reduces the symptoms of inflammation in a short time - Fluimucil.

    About the composition and structure of the medicine

    Fluimucil nasal spray is a well-known Swiss medicine for relieving symptoms of inflammation in the respiratory tract.

    The active component of the drug is acetylcysteine. This is a white or slightly yellow component, made in the form of a crystalline powder. Easily dissolves in water and purified alcohol.

    Acetylcysteine ​​is used as an expectorant, mucolytic, and detoxifying substance.

    This effect of the drug is due to disulfide bonds, which dilute sputum and mucous secretions.

    The pharmacological effect occurs due to an increase in the volume of mucous secretions. Thus, stimulation of mucosal cells occurs, which produce secret fluid. Having a stimulating effect on these processes, there is an outflow of liquid secretions.

    In addition, the active substance of the spray allows for an anti-inflammatory effect. This action is possible due to the suppression of the formation or development of radicals, which are responsible for the process of inflammation in the body.

    When taken, acetylcysteine ​​is rapidly absorbed, but patients should be warned about its low bioavailability. It does not exceed ten percent during initial use. The effect of the drug, which contains acetylcysteine, is achieved after three hours.

    "Flumicil" for sinusitis is active not only in the case of mild symptoms of inflammation, but also in case of purulent discharge.

    In addition, nasal drops with acetylcysteine ​​prevent the penetration of bacteria into the mucous membrane and normalize the functioning of the epithelium, and also have a stimulating effect on synthesizing substances that break down fibrin threads.

    The active component of the drug has a similar effect in case of damage to the upper respiratory tract.

    Fluimucil can be used for a runny nose, as well as in case of the following ailments:

    • to stimulate the respiratory tract;
    • purulent formation in the middle part of the ears;
    • otitis media;
    • acute inflammation of tracheitis;
    • pneumonia;
    • acute bronchiolitis;
    • chronic inflammation of sinusitis;
    • inflammation of the maxillary region;
    • acute sinusitis;
    • laryngotracheitis;
    • bronchitis;
    • sinusitis;
    • bronchial asthma.

    Fluimucil can be used for various operations in the upper jaw or nasopharynx.

    For the listed ailments, the medicine can be used only after consultation with the attending physician, since the drug has certain contraindications.

    Contraindications

    After determining the nature of the disease, it is necessary to determine all the signs and symptoms.

    Based on them, as well as after a comprehensive study of inflammation, the doctor will determine contraindications.

    If any of the following symptoms are present, taking the medication is prohibited.

    • inflammation of stomach and duodenal ulcers;
    • hypersensitivity to the active component of the drug;
    • When feeding your baby with breast milk, you should refrain from using the drug.

    The drug should not be used to treat children under two years of age. In the case of using Fluimucil tablets, the period of prohibition on using the drug reaches adulthood.

    In case of severe inflammation and the need to take Fluimucil when treating children, the doctor may prescribe the use of a solution of granules.

    In case of stomach ulcers or asthma inflammation, treatment should be carried out under the constant supervision of a doctor. Use the drug for hypertension or bleeding in the lungs with extreme caution, since the medicine has certain side effects with a long course of treatment.

    Do not use the product in case of renal and liver failure, as well as varicose veins in the esophagus.

    Side effects

    Side effects when taking medication occur only in case of an incorrect diagnosis or an incorrectly chosen dosage.

    dIn this case, the patient suffers from nausea, vomiting, dizziness, a feeling of heaviness in the abdomen, intestinal upset, heartburn and diarrhea.

    Manifestations of various allergic reactions are possible. In this case, patients complain of the formation of rashes on the skin, the appearance of hives and severe itching.

    Often there is a narrowing of the bronchi caused by muscle contraction in response to prolonged use of the medication.

    Very rarely, patients complained of the presence of extraneous noise immediately after taking the drug, as well as the appearance of nosebleeds and sudden cardiovascular failure, with loss of consciousness and the threat of death.

    Interaction

    When consulting with your doctor, you should indicate all the medications you are currently taking.

    Keep in mind that the simultaneous use of several cough medications can cause stagnation of mucous secretions.

    Such a negative symptom causes not only a constant cough, but also nasal congestion, as well as other extremely unpleasant factors.

    Do not use Fluimucil simultaneously with tetracyclines. This use can lead to a decrease in the effect of antibiotics and the active component of the spray. in the case of complex treatment, a break between medications is required for two hours. Remember that an antibiotic is necessary for sinusitis, since acute inflammation can only be gotten rid of using this method.

    If you have been prescribed medications that contain nitroglycerin, keep in mind that the vasodilator effect may be enhanced.

    Separately, it should be noted that the active substance of the drug “Fluimucil” reduces the toxic effect of paracetamol on the liver.

    special instructions

    Only the attending physician can prescribe Fluimucil, despite the fact that the drug is available without a prescription.

    When taking medication for bronchial asthma, you must strictly follow all the doctor’s advice, since this disease cannot be quickly treated.

    Experts give the same advice when treating bronchitis.

    How to carry out treatment correctly

    The instructions for using Fluimucil nasal drops indicate that the drops should only be used topically. For more complex diseases, the doctor may prescribe the drug intramuscularly or in the form of inhalations.

    Treatment of sinusitis

    In case of a runny nose, the remedy should be used as follows.

    First, cleanse your nasal passages with solutions prescribed by your doctor.

    Remember that treatment for adults is different from treatment for children. For the treatment of adults, inhalations are necessary.

    1. To do this, purchase a ten percent solution in an amount of three to nine milliliters.
    2. Carry out the procedure itself for fifteen minutes several times a day, but no more than three times.
    3. In case of chronic inflammation of rhinitis, treatment is necessary up to four times a day.
    4. Immediately after inhalation, clear your nose of mucus.

    The course of treatment should not exceed ten days. Five days are usually enough to treat a runny nose, but in the case of chronic inflammation, longer treatments are necessary. The exact number of days must be determined by the doctor.

    How to get rid of mucous discharge and cough with Fluimucil

    Use a nasal spray to treat a runny nose. Before introducing drops into the nose, it is necessary to perform sinus hygiene.

    To do this, rinse your nose with a solution of furatsilin or other medicinal components.

    Next, you need to spray the product into each nostril twice.

    Therapy should be carried out twice a day for one week. If the disease is more complex, complex treatment based on antibacterial drugs is necessary. But only the attending physician can prescribe them, so changing the course of treatment on your own is unacceptable.

    In case of inflammation of chronic runny nose and cough, it is necessary to use the product three times a day for no more than twelve days. If you do not notice the result on the fifth day of treatment, the medication is ineffective. In this case, it is necessary to reconsider the course of treatment with the help of a doctor.

    Reviews about "Fluimucil"

    Fluimucil is a popular drug for the treatment of mucous discharge and cough. It is used as an effective remedy in the fight not only against acute, but also chronic forms of the disease.

    This is evidenced by numerous reviews of “Fluimucil” for sinusitis.

    Marina Safonova: “I used Fluimucil as a cough remedy. He appeared to me and my daughter at the same time. The result surprised us; it not only reduced the reflex cough, but also acted as a strong expectorant.”

    Anna Gumerova: “I was treated with Fluimucil for inflammation of sinusitis. I used it morning and evening for six days in a row. The result was not long in coming. All the symptoms went away quite quickly, which affected the general mood.”

    Conclusion

    It is important to note that treatment of people of retirement age must be carried out under the supervision of several doctors. This is due to the side factors of Fluimucil. If blood pressure changes or other side symptoms develop, serious deterioration in health may occur.

    When treating older people, the course of treatment is significantly shorter, as is the number of applications.

    Directory of main ENT diseases and their treatment

    All information on the site is for informational purposes only and does not claim to be absolutely accurate from a medical point of view. Treatment must be carried out by a qualified doctor. By self-medicating you can harm yourself!

    Source: http://gorlonos.com/kapli/kak-kapat-v-nos-kapli-fluimutsil.html

    Fluimucil

    • Zambon, Italy
    • Expiration date: until 07/01/2020
    • Zambon, Italy
    • Expiration date: until 05/01/2020
    • Zambon, Italy
    • Expiration date: until 05/01/2020
    • Zambon, Italy
    • Expiration date: until 01/01/2019

    Fluimucil instructions for use

    Buy with this product

    Release form

    Granules for the preparation of a solution for oral administration.

    Tablets for preparing an effervescent drink with lemon flavor.

    Oral solution.

    Compound

      Fluimucil granules for oral solution
      1 sachet contains:
      Active substance: acetylcysteine ​​100 and 200 mg;
      excipients: aspartame; beta-carotene; orange flavor; sorbitol;
      Fluimucil effervescent tablets
      1 tablet contains:
      Active substance: acetylcysteine ​​600 mg;
      Excipients: citric acid; sodium bicarbonate; aspartame; lemon flavor.
      Fluimucil solution for oral administration
      1 ml of solution contains:
      Active substance: acetylcysteine ​​4 mg.

    Package

    Granules in sachets of 1 g; There are 20 and 30 sachets in a cardboard pack.

    Tablets in a package of 10 and 20 pcs.

    Oral solution in a bottle of 100, 150 and 200 ml.

    pharmachologic effect

    Liquefies mucus. The presence of sulfhydryl groups in the structure of acetylcysteine ​​promotes the rupture of disulfide bonds of acidic mucopolysaccharides of sputum, which leads to depolymerization of mucoproteins and a decrease in mucus viscosity. The drug remains active in the presence of purulent sputum.

    Acetylcysteine ​​has an antioxidant effect due to the presence of a nucleophilic thiol SH group, which easily donates hydrogen, neutralizing oxidative radicals.

    With the prophylactic use of acetylcysteine, there is a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis. The protective mechanism of acetylcysteine ​​is based on the ability of its reactive sulfhydryl groups to bind chemical radicals.

    Acetylcysteine ​​easily penetrates into the cell and is deacetylated to L-cysteine, from which intracellular glutathione is synthesized. Glutathione is a highly reactive tripeptide, a powerful antioxidant, cytoprotector that traps endogenous and exogenous free radicals and toxins.

    Acetylcysteine ​​prevents exhaustion and helps increase the synthesis of intracellular glutathione, which is involved in the redox processes of cells, i.e. promoting the detoxification of harmful substances. This explains the effect of acetylcysteine ​​as an antidote for paracetamol poisoning.

    Fluimucil is well absorbed when taken orally. It is immediately deacetylated to cysteine ​​in the liver. In the blood there is a dynamic balance of free acetylcysteine ​​and its metabolites (cysteine, cystine, diacetylcystine) bound to plasma proteins. Due to the high “first pass” effect through the liver, the bioavailability of acetylcysteine ​​is about 10%. Acetylcysteine ​​penetrates into the intercellular space and is predominantly distributed in the liver, kidneys, lungs, and bronchial secretions.

    After oral administration of 600 mg of acetylcysteine ​​to healthy volunteers, Cmax in plasma is reached after approximately 1 hour and is 15 mmol/l, with intravenous administration - 300 mmol/l. T1 /2 from plasma - 2 hours. Acetylcysteine ​​and its metabolites are excreted mainly by the kidneys.

    Fluimucil, indications for use

    Respiratory diseases accompanied by the formation of high-viscosity sputum (acute and chronic bronchitis, pneumonia, bronchiectasis, cystic fibrosis, bronchial asthma).

    Contraindications

    Hypersensitivity to acetylcysteine, peptic ulcer of the stomach and duodenum in the acute stage, age under 18 years (effervescent tablets).

    Directions for use and doses

    Granules for preparing a solution for oral administration are dissolved in 1/3 glass of water.

    Adults and children over 6 years old - 200 mg 2-3 times a day.

    For newborns - only for health reasons at a dose of 10 mg/kg under the strict supervision of a doctor. Children of the first year of life are given the resulting solution to drink from a spoon or feeding bottle. Children from 1 year to 2 years - 100 mg 2 times a day, from 2 to 6 years - 200 mg 2 times a day or 100 mg 3 times a day.

    The duration of treatment should be assessed individually. For acute diseases, the duration of treatment is from 5 to 10 days and up to several months for the treatment of chronic diseases (as recommended by a doctor).

    1 tablet is dissolved in 1/3 glass of water and taken 1 time per day.

    The duration of treatment should be assessed individually. For acute diseases, the duration of treatment is from 5 to 10 days and up to several months for the treatment of chronic diseases (as recommended by a doctor).

    Oral solution

    Children 2-6 years old - 200 mg 2 times a day; younger than 2 years mg 2 times a day; 6-14 years mg 2 times a day.

    Use during pregnancy and breastfeeding

    Use during pregnancy and breastfeeding is only possible if the intended benefit to the mother outweighs the potential risk to the fetus or child.

    Side effects

    When taken orally, in rare cases, nausea, heartburn, vomiting, diarrhea, skin rash, itching, urticaria, nosebleeds, and tinnitus are possible. Cases of the development of bronchospasm, collapse, stomatitis, and decreased platelet aggregation have been described.

    With parenteral administration - a slight burning sensation at the injection site, skin rash, urticaria.

    With inhalation administration - reflex cough, local irritation of the respiratory tract, stomatitis, rhinitis, rarely - bronchospasm (bronchodilators are prescribed).

    special instructions

    The drug contains aspartame, so it is not recommended for use in patients with phenylketonuria (granules, effervescent tablets).

    Drug interactions

    The combined use of acetylcysteine ​​with antitussives may increase sputum stagnation due to suppression of the cough reflex.

    When used simultaneously with antibiotics such as tetracyclines (excluding doxycycline), ampicillin, amphotericin B, they may interact with the thiol group of acetylcysteine, which leads to a decrease in the activity of both drugs. Therefore, the interval between taking these drugs should be at least 2 hours.

    The simultaneous use of acetylcysteine ​​and nitroglycerin can lead to an increase in the vasodilating and disaggregating effects of the latter.

    Acetylcysteine ​​eliminates the toxic effects of paracetamol.

    Check for interactions of other drugs with Fluimucil

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    Storage conditions

    In a place protected from light, at a temperature not exceeding 25 °C.

    Best before date

    • Fluimucil 200 mg. No. 20 grain. Dr.
    • Fluimucil solution for oral administration 20 mg/ml 100 ml bottle 1 piece
    • Fluimucil 600 mg tab. effervescent x10
    • Fluimucil granules for oral solution 200 mg sachet 20 pcs.
    • Fluimucil tablet effervescent. 600mg n10

    Latest reviews of Fluimucil

    The drug is very good. I recommend Fluimucil! And for the price it's good!

    After taking fluimucil, a severe headache begins, the temperature rises, muscles ache, breathing becomes difficult, fever, and sensitivity to light increases. Lasts for several hours, then goes away. Probably individual intolerance.

    An excellent mucolytic. I tried many different drugs, but this one turned out to be the most effective for me.

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    ** Delivery is carried out only for the preferential category of citizens on the basis of Art. 2 of the Federal Law of the Russian Federation of 01/09/1997 N 5-FZ “On the provision of social guarantees to heroes of socialist labor and full holders of the Order of Labor Glory” (as amended on 07/02/2013) and Article 1.1 of the RF Law of 01/15/1993 N “On the status of Heroes Soviet Union, Heroes of the Russian Federation and full holders of the Order of Glory." All orders are placed in a pharmacy (licensed) and collected by qualified pharmacists.

    Source: http://www.piluli.ru/product/Fluimucil

    Fluimucil

    • 🏪 You can buy Fluimucil on the website and in our pharmacies
    • 🚚 Fast delivery of Fluimucil to your home in Moscow
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    Fluimucil instructions for use

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    Fluimucil delivery and pickup in Moscow and the region

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    • Fluimucil, Zambon

    License: No. LO814 dated August 8, 2016, OGRN: 1988

    Source: http://www.eapteka.ru/goods/drugs/respiratory/sputum/fluimutsil/

    Fluimucil

    The drug Fluimucil is designed to effectively and quickly liquefy sputum. The strong mucolytic effect makes the drug indispensable in the treatment of inflammation of the respiratory tract with the concomitant formation of secretions of increased viscosity.

    Fluimucil's work is aimed at softening sputum, changing its volume and facilitating removal from the respiratory system. As a result, the patient’s condition is significantly alleviated and further treatment is more effective. The main active ingredient is acetylcysteine. The substance breaks intermolecular bonds in the secretion, thereby reducing its viscosity. The drug is active in the presence of purulent sputum. During treatment, there is an increase in less viscous sputum and a decrease in the viability of bacteria. The product has a sufficient antioxidant effect, neutralizing toxins. The product restores the normal course of redox processes in cells. If you have indications, then you can buy Fluimucil in Moscow cheaply and at a low price through an online store. ElixirPharm offers favorable purchases and reasonable prices in Moscow pharmacies.

    The peculiarity of the medicine is its ability to provide some anti-inflammatory effect by reducing inflammation in tissues. The drug is prescribed for the treatment of respiratory organs associated with difficult sputum discharge, such as tracheitis, pneumonia, emphysema, asthma, and so on. They treat purulent otitis, sinusitis, and sinusitis.

    The drug Fluimucil price from 113.50 R, reviews and availability

    Price from 113.50 RUR to 463 RUR

    Fluimucil Instructions for use

    Group

    Manufacturers

    Zambon S.p.A. (Italy)

    Leave procedure

    Available without a prescription.

    Fluimucil Analogs (7)

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    ✔ FLUIMUCIL in an online pharmacy in Moscow. ⭐ Price: from 113.50 RUR to 463 RUR ⭐ ✔ In stock. ✔ Instructions for use of FLUIMUCIL, reviews, cheaper analogues, composition.

    ✔ On the drug card you can study prices, look at analogues, composition, read customer reviews of the drug, which will help you choose and buy FLUIMUCIL in Moscow at a price from ⭐ 113.50 RUR ⭐

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    Source: http://elixir.farm/lekarstva/fluimucil/

    Fluimucil - instructions for use, price

    Instructions for use:

    Release form and composition

    Indications for use

    Directions for use and dosage

    Terms and conditions of storage

    Prices in online pharmacies:

    Fluimucil is an expectorant mucolytic drug.

    Release form and composition

    Dosage forms of Fluimucil:

    • oral solution: 20 mg/ml – transparent or slightly opalescent, colorless, with a characteristic raspberry odor and a slight sulfuric odor; 40 mg/ml – transparent, colorless or slightly yellow, with a characteristic odor of pomegranate and strawberries and a faint sulfuric odor (in dark glass bottles of 100, 150 or 200 ml, 1 bottle in a cardboard box);
    • solution for injection and inhalation: transparent, colorless, with a slight sulfuric odor; with prolonged contact with air after opening the ampoule, a slight pink-violet tint may appear (in dark glass ampoules of 3 ml, 5 ampoules in contour plastic packages, 1 package in a cardboard box);
    • granules for preparing a solution for oral administration: white-yellow with orange inclusions, have a characteristic orange, slightly sulfurous odor (1 g in multi-layer laminated bags, 20 or 60 bags in a cardboard box);
    • effervescent tablets: round, white, have a rough surface and a lemony, slightly sulfuric odor; the solution after reconstitution in water should be somewhat opalescent, have a characteristic smell and taste of lemon flavor (2 or 10 tablets in strip packs, 1, 2, 5 or 10 packs in a cardboard box).

    Composition of 1 ml oral solution:

    • active substance: acetylcysteine ​​– 20 or 40 mg;
    • auxiliary components (20/40 mg): methyl parahydroxybenzoate – 1/1.8 mg; sodium benzoate – 1.5/0 mg; edetate disodium – 1/1 mg; carmellose sodium – 4/4 mg; sodium saccharinate – 0.4/0.4 mg; propyl parahydroxybenzoate – 0/0.2 g; 70% sorbitol – 0/120 mg; raspberry flavor – 2.5/0 mg; strawberry flavor – 0/10 mg; pomegranate flavor – 0/2 mg; sodium hydroxide – up to pH 6.5/6.5; purified water – up to 1/1 ml.

    Composition of 1 ampoule of solution for injection and inhalation:

    • active substance: acetylcysteine ​​– 300 mg;
    • auxiliary components: sodium hydroxide – up to pH 6.5 (about 74 mg); edetate disodium – 3 mg; water for injection – up to 3 ml.

    Composition of 1 sachet for oral solution:

    • active substance: acetylcysteine ​​– 200 mg;
    • auxiliary components: sorbitol – 662.7 mg; aspartame – 25 mg; orange flavor – 100 mg; betacarotene – 12.3 mg.

    Composition of 1 effervescent tablet:

    • active substance: acetylcysteine ​​– 600 mg;
    • auxiliary components: sodium bicarbonate – 500 mg; aspartame – 20 mg; citric acid – 680 mg; lemon flavor – 100 mg.

    Indications for use

    • impaired sputum discharge associated with blockage of the bronchi by a mucus plug, in diseases such as pulmonary atelectasis, pneumonia, bronchitis, bronchiolitis, tracheitis, cystic fibrosis, bronchiectasis, lung abscess, laryngotracheitis, pulmonary emphysema, interstitial lung diseases;
    • otitis (purulent and catarrhal), sinusitis, sinusitis (to facilitate the discharge of secretions);
    • viscous secretion in the respiratory tract during postoperative/post-traumatic conditions (for removal).

    Additional indications for Fluimucil solution for injection and inhalation:

    • preparation for bronchoscopy, bronchography, aspiration drainage;
    • treatment of fistulas, the surgical field during operations on the mastoid process and the nasal cavity;
    • washing the middle ear, nasal passages, abscesses, maxillary sinuses.

    Contraindications

    • exacerbation of peptic ulcer of the stomach and duodenum;
    • fructose intolerance (for oral solution 40 mg/ml);
    • age up to 2 years (for oral solution and granules for the preparation of oral solution), up to 6 years (for solution for injection and inhalation) and up to 18 years (for effervescent tablets);
    • lactation period;
    • individual intolerance to the components of the drug.

    Relative (Fluimucil is prescribed with caution in the presence of the following diseases/conditions):

    • adrenal diseases;
    • pulmonary hemorrhage;
    • arterial hypertension;
    • peptic ulcer of the stomach and duodenum;
    • hemoptysis;
    • varicose veins of the esophagus;
    • bronchial asthma (for intravenous administration of Fluimucil solution for injection, since there is a high probability of bronchospasm);
    • renal/liver failure;
    • phenylketonuria (for granules for the preparation of oral solution and effervescent tablets; due to the presence of aspartame in the composition of the drug);
    • age up to 1 year (for intravenous administration of Fluimucil solution for injection, use of the drug is possible only in hospital settings in cases of vital indications);
    • pregnancy (the use of Fluimucil is possible only after assessing the ratio of benefits to possible risks).

    Directions for use and dosage

    Oral solution

    Fluimucil is taken orally.

    Recommended regimen for use of the drug (the daily dose of acetylcysteine ​​is indicated in parentheses):

    • children 2–5 years old: 2–3 times a day, 5 ml of a 20 mg/ml solution (200–300 mg);
    • children 6–14 years old: 3–4 times a day, 5 ml of a 20 mg/ml solution or 2 times a day, 4 ml of a 40 mg/ml solution (300–400 mg);
    • children over 14 years of age and adults: 15 ml of a 40 mg/ml solution (600 mg) once a day.

    Maximum per day – 600 mg of acetylcysteine.

    Solution for injection and inhalation

    How to use Fluimucil:

    • parenterally: route of administration – intramuscular and intravenous (preferably drip or slow stream over 5 minutes); dosage regimen – 1–2 times a day, 3 ml (adults), 1–2 times a day, 1.5 ml (children 6–14 years old) or 10 mg/kg per day (children under 6 years old; it is preferable to prescribe the drug in oral forms; intravenous administration to children under 1 year of age is possible only if there are vital indications in a hospital setting);
    • inhalation (aerosol therapy): a 10% solution of 3–9 ml (in ultrasound devices) or 6 ml (in devices with a distribution valve) is used. The duration of inhalation is from 15 to 20 minutes, the frequency of use is 2–4 times a day. The average course duration for acute conditions is 5–10 days, for chronic conditions – up to 6 months. Depending on the therapeutic effect and the patient's condition, the doctor may make changes to the dosage regimen. For children, the drug is prescribed in adult doses. With a strong secretolytic effect, the secretion is sucked out, and the frequency of inhalations and the daily dose are reduced;
    • locally (instillation into the nasal passages and external auditory canal): 1.5–3 ml per 1 procedure;
    • intratracheal (during therapeutic bronchoscopy for washing the bronchial tree): 1–2 ampoules or more per day (depending on clinical indications).

    The duration of the course is determined by the results of treatment. Fluimucil has high general and local tolerability, so its long-term use is possible.

    Before intravenous administration, the solution should be further diluted with 5% dextrose solution or 0.9% NaCl solution (ratio 1:1).

    For patients over 65 years of age, Fluimucil is usually prescribed in minimally effective doses.

    Granules for the preparation of solution for oral administration

    Fluimucil is taken orally, after dissolving a single dose in 1/3 glass of water.

    Recommended dosage regimen:

    • newborns (only if there are vital indications and under medical supervision) and children under 1 year: 10 mg/kg (from a feeding bottle or spoon);
    • children 1–2 years old: 2 times a day, 100 mg;
    • children 2–6 years old: 3 times a day, 100 mg or 2 times a day, 200 mg;
    • children over 6 years old and adults: 2-3 times a day, 200 mg.

    The duration of the therapeutic course is determined individually:

    • acute course of the disease: 5–10 days;
    • chronic course of the disease: up to several months.

    Effervescent tablets

    Fluimucil is taken orally (solution – 1 tablet in 1/3 glass of water).

    Recommended dosage regimen for adults: 1 tablet once a day.

    The duration of the therapeutic course is determined individually:

    • acute course of the disease: 5–10 days;
    • chronic course of the disease: up to several months.

    Side effects

    Oral solution, granules for solution, effervescent tablets

    In rare cases, the development of the following adverse reactions may occur: nosebleeds, tinnitus, disorders of the digestive system (in the form of nausea, heartburn, feeling of fullness in the stomach, skin rash, vomiting, diarrhea), urticaria, itching.

    There is also evidence of the development of collapse, bronchospasm, decreased platelet aggregation, and stomatitis.

    Solution for injection and inhalation

    • inhalation administration: rhinorrhea, respiratory tract irritation, reflex cough; rarely – bronchospasm, stomatitis;
    • intramuscular administration: skin rash, burning at the injection site, urticaria; with long-term therapy – functional disorders of the kidneys/liver.

    special instructions

    For patients with bronchial asthma and obstructive bronchitis, acetylcysteine ​​should be prescribed with caution under systematic monitoring of bronchial patency.

    A light sulfuric odor is characteristic of the active substance Fluimucil.

    The ampoule with solution for injection and inhalation must be opened before use. After opening, the drug can be used for 24 hours only for inhalation, provided it is stored in the refrigerator.

    With shallow intramuscular injection of Fluimucil and in the presence of hypersensitivity, the development of a slight and quickly passing burning sensation may be observed, so it is recommended to inject the drug deep into the muscle.

    Fluimucil solution (ready-made or obtained by dissolving tablets or granules) should not come into contact with metal/rubber surfaces.

    Drug interactions

    When Fluimucil is used in combination with certain drugs/substances, the following effects may develop:

    • antitussive drugs: increased stagnation of sputum, which is associated with suppression of the cough reflex;
    • antibacterial drugs - ampicillin, tetracyclines (except doxycycline), amphotericin B: decreased effectiveness of both drugs (recommended interval between doses is at least 2 hours);
    • nitroglycerin: enhancing its disaggregant and vasodilator effects;
    • paracetamol: eliminating its toxic effects.

    Fluimucil solution is pharmaceutically incompatible with other drug solutions.

    Terms and conditions of storage

    Store at temperatures up to 25 °C. Keep away from children.

    • solution for oral administration – 2 years (after the first opening of the package – 15 days);
    • solution for injections and inhalations – 5 years;
    • granules for the preparation of solution for oral administration, effervescent tablets – 3 years.

    Fluimucil: prices in online pharmacies

    Fluimucil effervescent tablets 600mg 10pcs

    Fluimucil 600 mg No. 10 effervescent tablets

    Fluimucil effervescent tablets 600 mg n10

    Fluimucil tbl spike. 600 mg No. 10

    Fluimucil granules 200mg 20pcs

    Fluimucil solution for oral administration 20 mg/ml 100 ml

    Fluimucil granules 200 mg No. 20 sachets

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