Gripferon drops for prevention

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Grippferon nasal drops: instructions and reviews

Grippferon is a drug that has antiviral, anti-inflammatory, immunomodulatory and antimicrobial effects.

This medicine has a wide range of applications and is used in the treatment of influenza, ARVI, bronchitis, pneumonia, and sinusitis.

Table of contents:

On this page you will find all the information about Grippferon: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Grippferon. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Interferon. Immunomodulatory drug with antiviral effect.

Conditions for dispensing from pharmacies

Available without a prescription.

How much does Grippferon cost? The average price in pharmacies is 320 rubles.

Release form and composition

The drug is produced in the form of dosed light yellow or colorless nasal spray and drops, in plastic bottles with a dropper of 5 or 10 ml. One dose of Grippferon spray contains:

  • At least 500 IU of interferon alfa-2b;
  • 4.1 mg sodium chloride;
  • 0.5 mg disodium edetate dihydrate;
  • 11.94 mg sodium hydrogen phosphate dodecahydrate;
  • Up to 1 ml of purified water;
  • 10 mg povidone 8000;
  • 100 mg macrogol 4000;
  • 4.54 mg potassium dihydrogen phosphate.

1 ml of Grippferon drops contains at least IU of human recombinant interferon alpha-2b, as well as a number of excipients similar to those present in the spray.

Pharmacological effect

The mechanism of action of the drug is based on blocking the reproduction of any viruses that enter the human body through the respiratory tract. Literally on the second day of treatment, the patient exhales significantly less viruses, which, of course, reduces the risk of infecting people who are in contact.

There is a wide variety of forms in which Grippferon is produced. These include drops for children, spray, and rectal suppositories. The drops are produced in a plastic bottle with a dispenser in a cardboard box, in which instructions for use are attached to the medicine.

Indications for use

What does it help with? The main reason to drip Grippferon into the nose of a child or adult is the treatment of acute respiratory viral infections and other viral lesions of the upper respiratory tract. In addition, such a medicine is also in demand for prevention.

Which dosage form is better - spray or drops?

Paradoxical as it may seem, whole battles are unfolding on this issue on many forums.

At the same time, according to some reviews, Grippferon spray is better, more effective and safer, while other reviews strongly recommend using exclusively Grippferon nasal drops. In fact, if you carefully read the instructions for use of the medicine, you will definitely find that Grippferon - both nasal drops and nasal spray - are absolutely identical both in composition and in concentration of the active substance.

And the drug is available in two different forms for a very simple reason. The thing is that it is not advisable for children under 3 years of age to use the spray.

Contraindications

The drug is contraindicated in case of individual intolerance to recombinant human interferon alpha-2 and its other components. It is not recommended to prescribe Grippferon to children and adults with severe allergic diseases.

Use during pregnancy and lactation

The use of any drug during pregnancy poses a danger to the unborn child. Grippferon is so safe that the use of this drug is indicated during pregnancy and lactation. The composition of the product cannot cause mutations in the fetus or developmental delays. However, it should be borne in mind that interferon passes into breast milk.

Pregnant women can safely use dosage forms of the drug such as nasal spray and drops. Gerippferon ointment cannot be used in the treatment of colds or flu, since this product contains loratadine. This substance is not used in the treatment of pregnant women.

Instructions for use

The instructions for use indicate that at the first signs of the disease, Grippferon is used for 5 days:

  • adults - 3 drops in each nasal passage 5-6 times a day (single dose 3000 ME, daily dose 00 ME).
  • aged 3 to 14 years - 2 drops in each nasal passage 4-5 times a day (single dose 2000 IU, daily dose 0 IU).
  • at the age of 1 to 3 years - 2 drops in each nasal passage 3-4 times a day (single dose 2000 ME, daily dose ME).
  • at the age of 0 to 1 year - 1 drop in each nasal passage 5 times a day (single dose 1000 IU, daily dose 5000 IU).

To prevent ARVI and influenza:

  • in case of contact with a patient and/or hypothermia, the drug is instilled in a single age dose 2 times a day. If necessary, preventive courses are repeated.
  • with a seasonal increase in incidence, the drug is instilled in an age-specific dose once in the morning at an interval of hours.

After each instillation, it is recommended to massage the wings of the nose with your fingers for several minutes to evenly distribute the drug in the nasal cavity.

How to properly put drops in a child's nose?

Like any nasal drops, Grippferon should be instilled correctly in young children in a lying position, with the child’s head turned to the side, into the lower nostril.

Following this, you need to turn the baby’s head to the other side and apply drops to the other nostril. It goes without saying that the nose must first be as cleansed as possible of mucous and purulent contents.

Side effects

During treatment with the drug, in rare cases it can cause side effects in the form of allergic reactions.

Overdose

Cases of overdose with Grippferon drops have not been described to date.

special instructions

Grippferon drops do not affect the speed of psychomotor reactions and the ability to concentrate.

Drug interactions

It is not advisable to use Grippferon simultaneously with vasoconstrictor drops. This can cause dry mucous membranes. When taking this medication, you do not need to take additional pain-relieving tablets.

Reviews

We have selected some people's reviews about the drug Grippferon:

  1. Ksenia . My daughter is five months old, she is breastfed, she suddenly fell ill, the temperature lasted for two days, there were no other symptoms. On the advice of the doctor, she began to give influenza on the second day of illness; at night that day there was no longer a fever. I don’t know if it was the medicine or constant breastfeeding that helped, but next time I’ll definitely use influenza.
  2. Nina. I am very glad that I learned about the drug Grippferon. It was recommended to me by my attending physician. At first I was not very confident in its effectiveness, but after using it, the result exceeded my expectations. Now I always use the drug as a preventive measure.
  3. Elena . The seven-year-old son swam in a cold river, after which he became very ill. At first they gave him antipyretics and cough syrup, but the symptoms only worsened. They called a doctor to the house and prescribed Grippferon drops for children. The disease began to subside on the fourth day after use, the child did not eat anything and became very weak. I expected a greater effect.

Analogs

An analogue of the drug for children is Genferon Light. Suitable for adults:

  • Alfiron
  • Interferon
  • Virogel (ointment)
  • Nazoferon (drops)
  • Laferobion (solution in ampoules)
  • Alpha-Inzon (injection solution)
  • Laferon (candles)
  • Derinat (drops)
  • Viferon (candles)

Before using analogues, consult your doctor.

Storage conditions and shelf life

If the bottle has not yet been opened, it can be kept at home during the entire shelf life (2 years) in the refrigerator, since the recommended storage temperature is from +2 to +8 degrees.

After the first use, the medicine from the printed bottle can be stored for no longer than 30 days. If after a month the drug is still used up, it should still be poured out, and it is unacceptable to bury it in the child’s nose.

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One comment

My daughter brought the virus from the garden, and her youngest daughter became infected. I was surprised when, instead of a bunch of different medications, the doctor recommended only one. The whole family used Grippferon and were very pleased with it. If treatment is started immediately, the period of illness is significantly shortened. The fever subsides on the second day, cough and snot go away after 3-4 days.

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Transcription of analyzes online

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Source: http://simptomy-lechenie.net/grippferon-kapli/

Grippferon

Description current as of 02/03/2016

  • Latin name: Grippferon
  • ATX code: L03AB05
  • Active ingredient: Interferon alfa-2b (Interferon alfa-2b)
  • Manufacturer: Firn M (Russia)

Compound

  • 1 ml of Grippferon drops contains at least IU of recombinant alpha-2b human interferon. Additional substances: sodium chloride, disodium edetate dihydrate, sodium hydrogen phosphate dodecahydrate, povidone 8000, potassium dihydrogen phosphate, water, macrogol 4000.
  • 1 ml (corresponding to 20 doses) of Grippferon nasal metered spray contains at least IU of recombinant alpha-2b human interferon. Additional substances: sodium chloride, disodium edetate dihydrate, sodium hydrogen phosphate dodecahydrate, povidone 8000, potassium dihydrogen phosphate, water, macrogol 4000.

Release form

  • The drops are a transparent pale yellow solution. 5 or 10 ml of solution in a plastic bottle with a dropper, 1 bottle in a paper package.
  • The spray is a clear, pale yellow solution. 10 ml of solution in a plastic bottle with a dispenser, 1 bottle in a paper package.

pharmachologic effect

Anti-inflammatory, immunomodulatory, antiviral effect.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Grippferon (nasal drops and spray) is a broad-spectrum agent (coronavirus, rhinovirus, adenovirus, parainfluenza, influenza and others). The intranasal route of administration ensures long-term contact with the mucous membranes of the nasal cavity, exerting an effect at the site of initial introduction and replication of respiratory viral particles. The activity of one bottle of the drug is comparable to the activity of one hundred ampoules of human leukocyte interferon.

Addiction and resistance to Grippferon usually does not develop. The drug does not require auxiliary symptomatic treatment (Panadol, Aspirin, vasoconstrictor drops against nasal congestion, sulfonamides). A carefully selected composition has drying and absorbing effects that enhance the therapeutic effect of the active component.

From the very beginning of taking the drug, relief of the main symptoms of the disease (fever, runny nose, pharyngeal congestion, headache) is recorded. The use of Grippferon at the first signs of the disease leads to its interruption. The duration of the disease is reduced on average by 35-45%.

Also, the use of the drug several times reduces the likelihood of developing complications: sinusitis, bronchitis, pneumonia. The use of Grippferon for the purpose of individual urgent prevention guarantees protection against infection up to 96%.

Pharmacokinetics

With the intranasal route of administration, the concentration of the active substance in the blood is much lower than the detection limit and has no pharmacological significance.

Indications for use

Contraindications

  • sensitivity to interferon-based drugs or any components of Grippferon;
  • severe allergic diseases.

Side effects

The development of allergic reactions is possible.

Instructions for use of Grippferon (Method and dosage)

Spray Grippferon, instructions for use

When the first signs of illness occur, the drug is used for 5 days according to the following schemes, taking into account age:

  • children under 1 year of age require the use of 1 dose of medication (500 IU) in the nasal passages five times a day (single dose is 1000 IU, daily dose is 5000 IU);
  • children 1-3 years old are administered 2 doses into the nasal passages three to four times a day (single dose is 2000 IU, daily dose is IU);
  • children 3-14 years old are administered 2 doses into the nasal passages four to five times a day (single dose is 2000 IU, daily dose is 0 IU);
  • persons over 15 years of age are administered 3 doses into the nasal passages five to six times a day (single dose is 3000 IU, daily dose is 00 IU).

To prevent influenza and ARVI, the spray is used according to the following schemes:

  • in direct contact with a sick person or in case of hypothermia, the medicine is used in a single age dose twice a day, once;
  • in case of seasonal increase in incidence, the medicine is used in an age-specific dose once in the morning every 1-2 days.

If necessary, preventive treatment is repeated.

Grippferon drops, instructions for use

When the first signs of illness occur, Grippferon nasal drops are used for 5 days according to the following schemes, taking into account age:

  • drops for children under 1 year of age are used in both nasal passages, 1 instillation five times a day (in children of this age, on the recommendation of a doctor, it may be more preferable to use suppositories);
  • for children 1-3 years old, 2 drops are instilled into the nasal passages three to four times a day;
  • for children 3-14 years old, 2 drops are instilled into the nasal passages four to five times a day (single dose is 2000 IU, daily dose is 0 IU);
  • for persons over 15 years of age, 3 drops are instilled into the nasal passages five to six times a day.
  • in case of direct contact with a sick person or in case of hypothermia, the drug is instilled once in a single age dose, 1 time in the morning and 1 time in the evening;
  • in case of seasonal increase in incidence, the drug is instilled in an age-specific dose once every 1-2 days in the morning.

After instillation, it is recommended to massage the lateral surfaces of the nose with your fingers for a minute to ensure proper distribution of the product in the nasal cavity.

Overdose

There is no evidence of drug overdose

Interaction

The use of vasoconstrictor intranasal drugs together with Grippferon is not recommended, because this contributes to excessive drying of the nasal mucosa.

Terms of sale

The drug can be purchased without a prescription.

Storage conditions

Keep away from children. Store at 2-8 degrees Celsius.

Best before date

Two years. It is allowed to store an opened bottle for no more than a month. It is forbidden to use after the expiration date indicated on the pack.

special instructions

Does not affect the ability to drive vehicles.

Grippferon analogs

Grippferon for children

The drug is approved for use in children. How to use drops and spray in children is described in the section “Instructions for use of Grippferon (Method and dosage).” The concept of “children's Grippferon” with special release forms and dosages does not exist; in young children it may be preferable to use other forms of interferon release, for example, suppositories for children.

Grippferon for newborns

It is allowed to use Grippferon for newborns; the method of application and dosage are described in the section “Instructions for use of Grippferon”.

Grippferon during pregnancy and lactation

Grippferon during pregnancy and breastfeeding is approved for use throughout the entire duration of these periods in doses appropriate for age.

Reviews about Grippferon

Reviews of Grippferon for children and adults in the vast majority of cases characterize the drug well. Reports of ineffectiveness and side effects are rare. The disadvantages of the drug include its high cost and short shelf life of an open bottle. Reviews of Grippferon during pregnancy do not indicate an increased incidence of side effects or any effect on the fetus.

Grippferon price, where to buy

The price of Grippferon drops 10 ml in Russia is rubles. In Ukraine, this form of issue will cost hryvnia.

The price of a 10 ml spray in Russia fluctuates within rubles. In Ukraine, a spray in such packaging costs approximately 350 hryvnia.

Often pharmacies are interested in the availability of the drug “children’s Grippferon”, but such a drug does not exist. The described release forms are used for both adults and children of all ages.

  • Online pharmacies in Russia Russia
  • Online pharmacies in Kazakhstan Kazakhstan

WER.RU

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Pharmacy IFC

BIOSPHERE

Education: Graduated from Vitebsk State Medical University with a degree in Surgery. At the university he headed the Council of the Student Scientific Society. Advanced training in 2010 - in the specialty "Oncology" and in 2011 - in the specialty "Mammology, visual forms of oncology".

Work experience: Worked in a general medical network for 3 years as a surgeon (Vitebsk Emergency Hospital, Liozno Central District Hospital) and part-time as a district oncologist and traumatologist. Worked as a pharmaceutical representative for a year at the Rubicon company.

Presented 3 rationalization proposals on the topic “Optimization of antibiotic therapy depending on the species composition of microflora”, 2 works took prizes in the republican competition-review of student scientific works (categories 1 and 3).

Thanks for the description. Very specific.

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Valentina: I, too, am all about diet and exercise. I hoped for loads, I thought that my healthy lifestyle.

Nina: I was on pills for a year and a half, then somehow everything calmed down. Mostly climatefit.

Elena: With the onset of menopause, the skin completely deteriorated and became dry. I saw a cream for .

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Source: http://medside.ru/grippferon

Drops "Grippferon" in the nose for children

With cold and flu season approaching, many mothers are thinking about protecting their son or daughter from viral infections. For preventive purposes, as well as for the treatment of acute respiratory viral infections, various immunomodulatory drugs are used, a representative of which can be called Grippferon in the form of nasal drops. Is it allowed to treat children with this drug and in what dosage is the drug used for prevention?

Release form

Grippferon in the form of nasal drops is presented as a transparent solution, bottled in plastic bottles of 5 or 10 ml. This liquid is usually colorless, but may have a light yellow color. The bottle has a dropper that helps you accurately measure a single dose of the drug.

Compound

The main component of the drug is recombinant interferon alpha-2b. It is contained in each milliliter of drops in a dose of at least IU. Povidone, sodium chloride, purified water and macrogol 4000 are added to it. Also, Grippferon's auxiliary substances are potassium dihydrogen phosphate, sodium dodecahydrite hydrogen phosphate and disodium edetate dihydrate.

Operating principle

Grippferon drops are classified as immunomodulatory agents that have antiviral as well as anti-inflammatory effects. After instillation into the nose, the drug penetrates the blood in a very small amount, which is not even determined by tests, so the effect of such a medication is exclusively local.

Indications

The main reason to drip Grippferon into the nose of a child or adult is the treatment of influenza and other viral lesions of the upper respiratory tract. In addition, such a medicine is also in demand for prevention.

At what age is it allowed to take it?

The medication is considered harmless to the child’s body, so it can be prescribed even for children under one year old. However, consulting a doctor before using this medicine in a child is still advisable.

Contraindications

Drops are not prescribed to children with intolerance to interferon or any other component of the drug. Also, young patients with severe allergies should not be treated with this remedy.

And now Dr. Komarovsky will tell us about children's antiviral drugs.

Side effects

Some children react to the use of the medicine with an allergic reaction. Other side effects from such drops are not recorded.

Instructions for use

Treatment

It is recommended to start dripping Grippferon as soon as the first symptoms of a viral infection appear. The duration of use of the medication is 5 days. The dosage and frequency of instillation depend on the age of the child:

  • For children of the first year of life, the medicine is administered in 1 drop (1000 IU) into each nostril 5 times a day, that is, the daily dosage is 5000 IU.
  • For a child 1-3 years old, 2 drops of the drug are dripped into each nasal passage, and the frequency of the procedure is 3 or 4 times a day. At one time, the baby receives 2000 IU of interferon, and per day - from 6000 to 8000 IU.
  • A single dosage for children aged from 3 to 14 years is also 2 drops, but the frequency of use increases to 4-5 times, so 8000 doIU of interferon is produced per day.
  • For children over 14 years old, 3 drops of Grippferon are injected into each nostril, which corresponds to 3000 IU of the active substance. The manipulation is carried out 5 or 6 times a day, so in total the patient receives a dose of the active ingredient per day.

Having dripped the medicine into the child’s nose, then you need to massage the wings of the nose, lightly pressing them with your fingers for several minutes. This will help the drops distribute more evenly throughout the mucous membrane.

Prevention

The drug can be used during the season of viral infections, instilled in the morning every day or every other day in the single dosage recommended for treatment. If the child has had contact with a sick person or has become hypothermic, the frequency of instillation changes - it is recommended to drip the drug in an age-appropriate single dose twice a day every day.

Overdose

The manufacturer does not provide data on the negative effects of too large doses of Grippferon.

Interaction with other drugs

You should not use Grippferon and intranasal medications with a vasoconstrictor effect at the same time, since this combination of medications will dry out the mucous membrane.

Terms of sale

To buy Grippferon for a child at a pharmacy, you do not need to present a prescription from a pediatrician. The average price of a bottle of drops is 250 rubles.

Storage conditions and shelf life

If the bottle has not yet been opened, it can be kept at home during the entire shelf life (2 years) in the refrigerator, since the recommended storage temperature is from +2 to +8 degrees. After the first use, the medicine from the printed bottle can be stored for no longer than 30 days. If after a month the drug is still used up, it should still be poured out, and it is unacceptable to bury it in the child’s nose.

Reviews

Grippferon drops receive a lot of good reviews from parents. The drug is praised for its convenient bottle, the ability to be used from birth, the absence of a bitter taste and its effective action. Many mothers confirm that the use of drops allowed them to avoid infection with the influenza virus or contributed to a faster recovery from ARVI.

Some parents consider the disadvantages of the medicine to be the high cost and small volume of the bottle, as well as the short shelf life after opening. In addition, there are reviews that mention the lack of effect from treatment with Grippferon.

Analogs

Instead of Grippferon, the doctor may recommend drugs with a similar composition and therapeutic effect, for example:

  • Viferon. This medicine also contains alpha interferon and is often prescribed to children for viral diseases, candidiasis and other diseases. It is produced in the form of suppositories, which can be used at any age, including premature babies. The medicine is also presented as a gel (prescribed from birth) and ointment (allowed from 1 year).
  • Genferon Light. As part of this medication, taurine was added to interferon. It comes in several forms - suppositories, nasal drops and nasal spray. The drug is used in drops and suppositories from birth, and the spray form is used in the treatment of adolescents over 14 years of age.

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Source: http://www.o-krohe.ru/protivovirusnye/kapli-v-nos-grippferon/

Grippferon is an excellent medicine for the flu

Grippferon is a very popular drug that is used for the prevention and treatment of acute respiratory diseases in childhood and adulthood, and especially influenza.

What is the composition of influenzaferon?

The drug belongs to the pharmacological group of cytokines. The basis of Grippferon is the protein interferon alpha 2b, which is synthesized by genetic engineering. Substances obtained in this way are called recombinant. In addition to the interferon protein, Grippferon contains additional substances (disodium edetate dihydrate, sodium chloride, sodium hydrogen phosphate dodecahydrate, potassium dihydrogen phosphate, povidone, macrogol, purified water) - interferon stabilizers, which keep it active for a long time.

Interferon was first produced using genetic engineering in Russia at the end of the twentieth century. Over the next 15 years, scientists developed the optimal composition of stabilizers that would not affect the properties of interferon. After much research, Grippferon was developed, which was more effective than the outdated human leukocyte interferon.

Grippferon is active against the causative agent of influenza, coronaviruses, rubella viruses, respiratory viruses of an unspecified type and many others. The drug has a large list of indications. Grippferon instructions for use, which indicates only two contraindications - individual intolerance to the components of the drug and severe allergic reactions, is not only an effective remedy, but also safe for treatment.

What is interferon alpha 2b recombinant?

Interferon belongs to special proteins - cytokines, which are produced by white blood cells and are part of the immune system.

Depending on their properties, interferons are divided into three groups - alpha, beta and gamma. Interferon alpha is most active in destroying ARVI viruses. The mechanism of action on the virus is to suppress their reproduction and activity, as well as other intracellular parasites.

How is interferon produced?

To isolate interferon alpha, a bacterial cell must be introduced into a piece of human DNA isolated from white blood cells that has a certain type of protein. With the help of modern high-tech technologies, the synthesized interferon is thoroughly purified. Thanks to this, the drug has almost no side effects, unlike its analogues.

The risk of side effects arises when the drug is administered intravenously, because interferon is still a foreign protein and can cause an immediate allergic reaction. Grippferon is produced only in the form of solutions for topical use, so a minimal amount of it enters the blood, which very rarely causes allergies.

Spray or nasal drops Grippferon, which is better?

Grippferon is a liquid, transparent, colorless or light yellow product in the form of a spray and nasal drops, which acts in the nasal mucosa.

Note! Grippferon is just a spray and nasal drops! There are no other dosage forms of Grippferon.

Spray and drops Grippferon have an identical composition, respectively, their action and effectiveness are the same. Grippferon drops are intended for infants, since the spray cannot be used at this age in order to avoid reflex respiratory arrest. Drops are easier to dose and do not enter the middle ear through the nasopharynx, and the spray is more evenly distributed.

Advice! After putting the drops into your child's nose, massage both nostrils for better distribution of the drug.

Indications for use of Grippferon

Grippferon is an antiviral, anti-inflammatory and immunomodulatory drug. Its main purpose is the prevention and treatment of influenza and other acute respiratory viral infections in children and adults. Grippferon during pregnancy will not harm either the mother or the fetus.

Grippferon for children

Grippferon is often prescribed by pediatricians to their young patients for preventive and therapeutic purposes. The drug is safe even for newborn babies. But, despite its safety, under no circumstances should you use Grippferon uncontrolled and without a doctor’s advice, because it is still a medicine, not water.

As you know, newborn children receive antibodies from their mother’s milk that protect them from various diseases, including influenza. But it is impossible to say for sure that children under the first month cannot get sick with ARVI or influenza. Therefore, during a flu epidemic, it is better to drop Grippferon drops into the nose of the mother who is breastfeeding the baby, and the drug will certainly enter the baby’s blood and create additional protection against viruses. If an infant or older child has a weakened immune system, then the use of Grippferon will be indispensable. Grippferon is an effective prevention of influenza and other acute viral respiratory infections.

Many parents are faced with the fact that their children did not have time to go for a walk in the yard or attend kindergarten, but already have signs of ARVI. Grippferon in this case is a great salvation. The child will not get sick as often. Another very convenient thing is that the drug for adults and children is available in the same composition, the only difference is in the volume (5 and 10 ml). You don’t overpay, since you buy one bottle for yourself and your child, just take a larger volume.

Children's Grippferon is available in a 5 ml bottle and has a special dropper for convenient instillation into the nose. This amount of the drug will be enough not only for the prevention of diseases, but also, if necessary, for treatment.

How to use Grippferon

For the purpose of treatment and prevention, the drug is instilled or sprayed into the nose. Intranasal administration of Grippferon is the only way to use it. The dosage regimen and dosage depend on the child’s age and condition.

For the treatment of influenza and ARVI, Grippferon is used for five days in the following dosages:
  • For children under 12 months, Grippferon is instilled one drop (500 IU) into each nostril 5 times a day. Intervals between applications should be approximately the same duration. The daily dose should not exceed 5000 IU;
  • For children from 12 months to 3 years, the drug is instilled two drops into each nostril 3-4 times a day. The daily dose should not exceed 8000 IU;
  • children from 3 to 14 years old are prescribed two drops in each nostril 4-5 times a day, not exceeding the daily dose of ME;
  • children over 15 years old and adults - 3 drops per day in each nostril. The daily dose is not higher than IU;
  • Grippferon during pregnancy is used in age-specific dosages.

For the purpose of prevention, Grippferon should be used in the following dosages:

  • if there is contact with a patient with influenza or ARVI, Grippferon should be instilled or injected in the morning and evening in an age-specific dose, throughout the entire period of contact;
  • during seasonal influenza epidemics, the drug is used once a day in the morning at an age-specific dose.

Note! Grippferon can be used by drivers and representatives of other professions that require increased attention, since it does not slow down a person’s physical and mental reactions.

  • Before using Grippferon, carefully read its instructions for use.
  • Before instillation, thoroughly clean the nasal passages of crusts, mucus or purulent contents.
  • To instill drops into your baby, lay him on his back, turn his head to the side and instill in the lower nostril, then turn his head to the other side and instill in the other nostril.
  • After instilling the drops, massage the child’s nose so that the drug is evenly distributed throughout the mucous membrane.
  • The spray bottle should be shaken before use, then remove the cap and spray one dose into each nasal passage.
  • The antiviral effect of Grippferon is more effective if you start taking it from the first day of the disease. Three days after the first signs of influenza and ARVI appear, the drug acts as an immunomodulator, speeds up recovery, eases the course of the disease and reduces the risk of complications.

Grippferon during pregnancy

Grippferon during pregnancy is an excellent prevention of viral infections or relief of illness if you do get sick. This is one of the few means of treating and preventing influenza and ARVI that is allowed for such an important condition. Grippferon is used during pregnancy at any stage, unless the woman suffers from severe forms of allergies or has an individual intolerance to the components of the drug. The remedy can be prescribed in any form. Both nasal spray and drops will bring the expected effect, but you should still use Grippferon after consultation with your obstetrician-gynecologist or therapist. If an adverse reaction occurs, stop using the drug immediately and tell your doctor.

Grippferon should be used from the first day of symptoms of influenza or ARVI to stop the disease, since viruses can cross the placenta and negatively affect the fetus - they cause disruption in the formation of organs and systems, leading to miscarriages and premature birth.

Is it possible to replace Grippferon?

As an analogue, if Grippferon is not available, the pharmacist can offer you Viferon or Derinat. Unlike Grippferon, Viferon has a different dosage and acts systemically, which increases the risk of adverse reactions. So, we can say that these drugs are not completely identical and cannot be independently replaced with each other. More similar to Grippferon is Derinat (sodium deoxyribonucleate), which is also produced using genetic engineering techniques. Derinat has immunomodulatory, anti-inflammatory and antiviral effects, although it has a composition that is radically different from Grippferon.

If suddenly Grippferon is not available in the pharmacy, it is better to consult with your doctor about an adequate replacement of treatment.

How much does influenza cost?

The price of Grippferon in the Russian Federation, relative to other antiviral drugs with similar effectiveness, is small. Prices for Grippferon are as follows:

  • Dosed nasal spray, 500 IU/dose in a plastic bottle, 10 ml, costs an average of 300 rubles;
  • Nasal drops, IU/ml. in a plastic bottle of 5 ml with a drip dispenser costs an average of 160 rubles, and 10 ml – 230 rubles.

Based on what was said above about Grippferon, we can summarize the following:

  • Grippferon is well tolerated by patients when taken;
  • Has a minimal number of side effects and contraindications;
  • The drug is highly effective in the fight against influenza virus, rubella, parainfluenza and other pathogens of acute respiratory infections;
  • Grippferon can be used as an additional drug in the treatment of pneumonia, bronchitis;
  • The drug cannot be taken uncontrolled, as it can aggravate the condition of some autoimmune diseases;
  • Grippferon for prevention should be taken only if your immunity is weakened. A healthy immune system is able to protect itself from viruses.
  • Grippferon is used in pregnant women and children only strictly if indicated.

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5 comments to the article “Grippferon is an excellent medicine for the flu”

Great drops! A month after giving birth, I managed to catch the flu, but there was no way to treat it - I was breastfeeding the baby. Our pediatrician advised us to instill these drops a couple of times a day, on the second day the fever subsided, and on the fourth everything went away. A big plus of the drops is that babies can already be given them from one month of age. Now I always have them on hand.

I recently caught the flu, and Grippferon drops helped me get back on my feet much faster, even my runny nose soon went away. The drops do not cause allergies or irritation of the mucous membranes, and the price is quite reasonable.

A friend who caught the flu took Grippferon drops, which helped her recover quickly. She recommended these drops to me when I also got the flu. The drops are good, they helped me. And reasonable price.

Very good drops, my daughter brought the virus from school and the little one caught it, she was three months old, it was all gone in three days. I recommend

For fools, a complete lie, a waste of money! People don't believe it!

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Source: http://www.medware.ru/infekcionnae/grippferon-pri-grippe.html

Grippferon

Description of the drug

Grippferon (nasal drops) is an effective and safe drug for the prevention and treatment of acute respiratory viral infections (ARD, ARVI) and influenza. It is approved for use even in children under one year of age (including newborns) and pregnant women.

The main active ingredient of Grippferon is highly active recombinant (obtained by genetic engineering) interferon a-2. The drug is absolutely safe in terms of virus contamination, which is very important in the age of widespread hepatitis B, C, D, HIV, CMV and other blood-borne infections.

The mechanism of action of interferon (Grippferon) is based on preventing the reproduction of any viruses that enter the body through the respiratory tract. Already on the second day of using Grippferon, the patient’s number of viruses released during breathing is significantly reduced, and, accordingly, the risk of infection of people in contact with him is reduced.

Unlike other interferon preparations, Grippferon prevents the multiplication of viruses in the nasal mucosa, that is, where they enter the body.

Grippferon has no analogues on the world market and surpasses all other drugs in the versatility of its effect on acute respiratory viral infection:

  • Blocks the reproduction of all types of human respiratory viruses.
  • It has high therapeutic effectiveness.
  • Highly effective as an emergency prevention drug.
  • There is no addictive effect to the drug.
  • Viruses are not able to acquire resistance to the action of Grippferon (interferon does not interact with viruses, it blocks their reproduction mechanism).
  • Non-toxic and safe.
  • Approved for use in children under one year of age, including newborns.
  • Grippferon is approved for use during pregnancy and lactation.
  • Reduces the number of complications in patients with acute respiratory infection by 60-70%.
  • Reduces the number of medications taken by the patient by 50-70%.
  • There are no contraindications for compatibility with other drugs, including antiviral drugs.
  • Can be used in conjunction with vaccination.
  • Tens of times reduces the amount of viruses released from the nose in patients with acute respiratory infection (analogous to a bandage), that is, it significantly reduces the infectiousness of the patient.
  • Has a pronounced anti-epidemic effect.

What viruses cause ARVI and influenza?

Today, more than 2000(!) serotypes of the influenza virus and more than 200 types of other respiratory viruses are known (each of them can also have hundreds of varieties). And any of these viruses can cause ARVI.

During a “flu epidemic,” 10 to 25% of those infected suffer from the flu itself. The remaining 90-75% of patients suffer from other respiratory diseases, against which vaccination and influenza medications do not protect. And the consequences of these ailments, especially for a weakened body, can be no less destructive than with the flu. Grippferon affects not only the influenza virus, but also other respiratory viruses.

Distribution of respiratory viruses during an "influenza epidemic" (Emergency Department, Royal Children's Hospital):

Clinical and experimental studies of Grippferon were carried out on 4450 subjects in 14 research and clinical centers in Russia and Ukraine.

Antiviral effect of Grippferon

Experimental studies have shown a pronounced antiviral effect of Grippferon on:

  • All strains of the human influenza virus, including H1N1: studies were carried out on strains A/Krasnoyarsk/18/05 (H1N1), A/SPb/03/05 (H1N1), A/Krasnoyarsk/8/05 (H1N1), A /Novosibirsk/5/05(H1N1).
  • Human adenovirus AdV 6.
  • Respiratory syncytial virus, Rendall strain.
  • “Human coronavirus HCoV/SPb/01/03 (229E)” (one of the strains of this virus caused the SARS epidemic).
  • Rubella virus strain "Orlov".
  • Edmonston vaccine strain of measles virus.
  • Vaccine strain of mumps virus L-3.
  • Parainfluenza virus type 2, strain PG2/SPb5/11/03.
  • Avian influenza virus (A/Duck/Singapore/R/F119-3/97 (H5N2).
  • Lethal strain of avian influenza (A/chicken/Kurgan/Russia/2/2005 H5N1).

Indications for use

  1. Prevention and treatment of ARVI, influenza, colds:
    • in children from birth and adults, including pregnant women;
    • in patients who often and for a long time suffer from diseases of the upper respiratory tract;
    • in people prone to allergic reactions; upon contact with patients with ARVI and influenza;
    • with hypothermia.
  2. Prevention of acute respiratory viral infections and influenza in organized groups (children and adults), among “at-risk” populations - health workers, teachers, etc. (especially during an epidemic).
  3. Emergency prevention of influenza and ARVI. Unlike a vaccine that creates long-term resistance to certain strains of the influenza virus, Grippferon is used primarily in cases where there is a real threat of acute respiratory infection (in close contact with a patient, during an epidemic, during a cold, etc.), then available for emergency prevention. A single dose of the drug for individual emergency prevention greatly reduces the risk of the disease.
  4. Prevention and treatment of bird flu.

Instructions for use of Grippferon

At the first signs of influenza or ARVI, Grippferon is instilled into the nose for 5 days:

  • at the age of 0 to one year, 1 drop in each nasal passage 5 times a day;
  • at the age of 1 to 3 years, 2 drops in each nasal passage 3 times a day;
  • aged 3 to 14 years, 2 drops in each nasal passage 4 times a day;
  • adults: 3 drops in each nasal passage every 3-4 hours.

For prevention, the drug is instilled in an age-specific dosage 1-2 times a day during contact with the patient. If necessary, preventive courses are repeated.

After each instillation, it is recommended to massage the wings of the nose with your fingers for several minutes to evenly distribute the drug in the nasal cavity.

When using Grippferon, there is no need for vasoconstrictor therapy; it itself relieves swelling of the mucous membrane.

Grippferon is approved for use throughout the entire period of pregnancy in accordance with the age-specific dosage. To find out how much Grippferon to take during pregnancy, consult your doctor.

Treatment with Grippferon" when the very first signs of the disease appear, leads to the removal or significant weakening of its main symptoms (runny nose, cough, fever, headache, nasopharyngeal congestion, etc.) On average, the duration of the disease is reduced by 30-50%. Grippferon in uncomplicated cases does not require additional symptomatic treatment (aspirin, Panadol, sulfonamides, vasoconstrictor nasal drops). At elevated temperatures, Grippferon is combined with antipyretic drugs. The use of Grippferon several times reduces the risk of complications - bronchitis, sinusitis, pneumonia, etc. The use of the drug for preventive purposes during an epidemic in organized groups reduces the incidence rate by 3 times, and in risk groups - up to 5 times.

In the gynecology section you will find information about viral infections.

Also in one of the sections of our website there is information about vaccination against rabies.

Source: http://ztema.ru/drugs/grippferon

Features of the use of influenza in newborns

Respiratory viral infections in young children require the selection of the correct treatment regimen to allow a quick recovery and reduce the risk of possible complications. For infants, the treatment regimen often includes immunomodulatory and antiviral drugs.

Pediatricians recommend the use of Grippferon for newborns. This medicine can be used for both therapeutic and prophylactic purposes, and its effectiveness largely depends on following all the rules contained in the instructions for use.

Composition, pharmacological action and release form of Grippferon

Grippferon is a Russian-made medicine. The main active ingredient of the drug is alpha-2b interferon. The mechanism of the antiviral action of the drug is based on the ability of interferon to synthesize cellular proteins with antiviral activity.

Instructions for use indicate that the drug is used for:

  1. Treatment of influenza and acute respiratory infections in adults and children
  2. Prevention of possible infection during epidemics

If treatment for a runny nose, cough, or sore throat begins immediately, then your health will not suffer much. That is, the disease occurs in a mild form and at the same time the risk of severe complications - sinusitis, bronchitis, pneumonia - is reduced.

The drug influferon has several important advantages, these are:

  1. Impact on all types of human respiratory viruses
  2. No toxicity. Allergies rarely develop to influenza and
  3. Possibility of use for the treatment and prevention of influenza in children under one year of age, including newborns
  4. No addictive effect
  5. Compatible with all medications
  6. Reducing the release of virus from the nose during illness, which reduces the infectiousness of the sick person

As noted by reviews of people using influenzaferon in the first days of a respiratory infection, when using this medication the disease was easier, and the use of other drugs was minimal.

Grippferon is available in several dosage forms: spray, drops, ointment. Children under one year of age are recommended to use ointment and drops. The spray is prescribed only after three years.

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Many women after childbirth face the problem of excess weight. For some, it appears during pregnancy, for others, after childbirth.

  • And now you can no longer afford to wear open swimsuits and short shorts...
  • You begin to forget those moments when men complimented your flawless figure.
  • Every time you approach the mirror, it seems to you that the old days will never return.

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Features of treatment of children with Grippferon

Despite all the safety and high effectiveness of the drug Grippferon, you should not use it without special indications. Healthy newborn children who receive mother's milk in the first months have a fairly high immunity and do not need outside help.

It is also necessary to take into account that in children a runny nose can be physiological. That is, if there are no other symptoms of a respiratory infection, then there is no need to use any immunomodulatory drugs. For children under one year of age, drops can be used for incipient runny nose, fever, and symptoms of intoxication caused by influenza and colds.

Influenzaferon can also be used when you plan to visit a public place when the threshold for the incidence of respiratory infections is exceeded. To do this, it is better to use ointment, a small amount of it is injected into the nostril, and massaged a little on top for good distribution of the product. The ointment can also be used for prevention after contact with a sick person. Before its administration, the child’s nose must be cleaned; it is enough to use the ointment once or twice a day.

How many days to use Grippferon depends on the course of the disease. It is recommended to administer the drug until complete recovery. The effectiveness of interferon also depends on what day of illness the drug was given. Drops should be started to be used at the first signs of the disease.

The instructions for use explain that starting treatment on the fourth or fifth day of illness is no longer effective.

When using Grippferon, it is necessary to take into account that the therapeutic effectiveness of the drug is maintained only if its storage conditions are observed. The medicine must be stored in the refrigerator, after opening for no more than 30 days. Since the price of Grippferon is quite high, it is better when prescribing the drug to small children to buy it in a 5 ml bottle.

Dosage

Gripferon drops can be used in children under one year of age depending on their purpose. For prevention, the recommended dose is 1 drop twice a day, the general course of use is from two to four weeks. The spray is used for children over three years of age, one or two sprays into each nostril.

If Grippferon for infants is prescribed for treatment, then it is necessary to drip one or two drops of the medicine into each nasal passage up to 4 times a day. Treatment should be continued for several days until complete recovery. The drug is dripped after cleansing the nose, first you need to turn the baby's head to one side and introduce the medicine into the lower nostril, massage it and then carry out this manipulation on the other side.

The spray is not prescribed to children under three years of age due to the fact that there is a possibility, due to the anatomical features of the nasopharynx in young children, of the drug components getting into the inner ear. When treating older children, it is the spray that deserves positive reviews; its smallest components easily and quickly penetrate the entire mucous membrane, and therefore fight all viruses.

How to choose a flu medicine for children

If you read reviews about treating children for the flu, you will notice that parents use not only Gripferon, but also drugs such as Derinat or Viferon. Which ones are more effective, safer and better for babies? This question naturally interests mothers. Sometimes the choice is determined by the price, so not everyone wants to overpay for the advertised brand.

The instructions for use for each drug explain in detail in which cases Viferon is used, and in which cases Derinat is needed. Only a qualified doctor can understand these nuances, therefore, in the absence of special knowledge, it is necessary to rely on the experience of a specialist, and not on people’s reviews.

Derinat

Derinat is considered somewhat stronger compared to Grippferon. This drug affects not only viruses, but also bacteria and fungi. It is recommended to drip it into the nasal passages for a runny nose and an incipient cold in the first two days, 1-2 drops every hour and a half.

Derinat is used immediately from birth, its effectiveness is high if treatment is started immediately. Derinat is also used if the child has allergies, since this medicine contains an antiallergic component.

The price of Derinat is not much different from gripferon; it is also stored after opening for no more than a month.

Viferon

Viferon, unlike Grippferon, does not have such a release form as drops. This drug is available in the form of rectal suppositories, gel or ointment. Viferon gel and ointment are used to lubricate the mucous membrane of the nasal passages for preventive purposes.

Viferon suppositories have only a therapeutic effect and act not only locally, the components of the suppository penetrate into the bloodstream and affect the entire body. Viferon suppositories are best used as part of complex treatment; they are prescribed not only for respiratory infections, but also for bronchitis and pneumonia to improve immunity.

The price of the drug Viferon depends on the form of its release and on the amount of the active substance. Children under one year of age are prescribed Viferon 1; older children are prescribed a drug with a high content of interferon. How many days Viferon should be used depends on the nature of the disease.

When treating children, you do not need to rely on your own knowledge or on reviews of relatives’ medications. The best and most correct decision is a consultation with a pediatrician, who, based on the child’s condition and the presence of concomitant pathologies, can prescribe the correct course of therapy.

For prevention, it is better to use Derinat or Grippferon; if treatment is already necessary, then Viferon can be added to the main treatment regimen.

The price of any of these drugs depends on the form of release, the quantity of the drug and the markups of the pharmacy chain. Grippferon in the form of drops costs 250 rubles for a 10 ml bottle, the price for 5 ml of the product is slightly lower. The price for Derinat in nasal drops is above 280 rubles per 10 ml bottle. Derinat is more expensive for injections and external use.

When using interferon-based anti-flu drugs for children, it is always necessary to take into account that they have an immunomodulatory effect, that is, they interfere with human immunity.

Derinat, Viferon, Grippferon can be used for prevention or treatment no more than once every six months. If these drugs are administered to a child uncontrollably, it can be achieved that the body will no longer be able to cope with even a small amount of viruses and bacteria that have entered the nasopharynx. When taking care of the health of your baby, you must always act wisely, otherwise, instead of benefiting, you can cause harm to your baby.

Many women after childbirth face the problem of excess weight. For some, it appears during pregnancy, for others, after childbirth.

  • And now you can no longer afford to wear open swimsuits and short shorts...
  • You begin to forget those moments when men complimented your flawless figure.
  • Every time you approach the mirror, it seems to you that the old days will never return.

But there is an effective remedy for excess weight! Follow the link and find out how Anna lost 24 kg in 2 months.

Many women after childbirth face the problem of excess weight. For some, it appears during pregnancy, for others, after childbirth.

  • And now you can no longer afford to wear open swimsuits and short shorts...
  • You begin to forget those moments when men complimented your flawless figure.
  • Every time you approach the mirror, it seems to you that the old days will never return.

But there is an effective remedy for excess weight! Follow the link and find out how Anna lost 24 kg in 2 months.

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The information presented on the site is for informational purposes only. Cannot be a substitute for qualified medical care. The selection and prescription of medications, treatment methods, as well as monitoring their use can only be carried out by a pediatrician. Be sure to consult a specialist.

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Source: http://ogrudnichke.ru/lechenie/grippferon-dlya-novorozhdennyx-osobennosti-primeneniya.html