Chloride instructions for use

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Calcium chloride

Instructions for the drug

Analogues, synonyms

Glyxyl : Potassium chloride : Xylate : Lactoxyl : Magnesium sulfate : Sodium bicarbonate : Plerigo

Popular questions

Calcium chloride solution: application

Calcium chloride is one of the popular drugs for replenishing calcium deficiency in the body.

Table of contents:

It is produced in the form of a solution for internal use and a solution for intravenous administration. Calcium takes part in the formation of bone tissue, muscle contraction, blood clotting, and myocardial activity. The drug reduces the permeability of vascular walls and cells, prevents the development of inflammation, increases resistance to infections and the secretion of epinephrine by the adrenal glands. When administered intravenously, calcium chloride has a diuretic effect and stimulates the sympathetic part of the nervous autonomic system. The drug is prescribed for increased needs for calcium during periods of increased growth in the body, during pregnancy and lactation, for bleeding and allergic diseases, bronchial asthma, rickets, tuberculosis, colic, psoriasis, eczema, inflammatory processes, nephritis, eclampsia. The solution for internal use is prescribed twice or thrice a day. For intravenous administration, a 10% solution of calcium chloride is diluted with a solution of dextrose or sodium chloride and administered slowly, 6-8 drops per minute.

Calcium chloride for allergies

To treat allergies, in addition to antihistamines, calcium chloride is also used as an additional remedy. It cleanses the blood of allergens, toxins, harmful substances, has a detoxification effect and helps reduce allergic manifestations. But allergies cannot be cured with calcium chloride alone, and in case of acute symptoms, intravenous infusions of calcium chloride must be given and possibly the use of hormonal drugs. For minor manifestations of allergies, it is possible to use the drug orally, a tablespoon of solution.

Peeling with calcium chloride

Peeling with calcium chloride is suitable for combination, normal and oily skin prone to acne and blackheads. Peeling will cleanse facial pores, reduce inflammation, dry out small pimples, and whiten the skin. In order not to dry out the skin, make it flaky and not get pigmentation, you need to exfoliate correctly and not overdo it. For the procedure you will need a 5 or 10% solution and ordinary baby soap. First you need to clean your face of makeup and impurities and dry it. Then, using a cotton pad, apply the product solution to your face, wait until it dries completely and repeat the application. You need to do this 3-4 times until you feel tightness and tingling. Avoid the area around the eyes and lips! Then, using soapy fingers, remove the calcium chloride film from your face, moving along the massage lines, resulting in the formation of soap flakes. The moisture will be absorbed after washing and there is no need to dry your face with a towel. The whole procedure takes about minutes. During peeling, calcium chloride interacts with sodium and calcium salts of higher carboxylic acids contained in soap, resulting in the formation of insoluble calcium salts that roll off, taking with them the top layer of keratin scales.

Source: http://medhall.ru/kalciia-chlorid/

CALCIUM CHLORIDE INSTRUCTIONS

Prices for CALCIUM CHLORIDE

The drug eliminates calcium ion deficiency. Calcium ions take part in the transmission of nerve impulses, contraction of smooth and skeletal muscles, in the functional activity of the myocardium, and blood clotting; necessary for the formation of bone tissue and the functioning of other systems and organs. The concentration of calcium ions in the blood decreases in many pathological processes; severe hypocalcemia contributes to the occurrence of tetany. Calcium chloride, in addition to eliminating hypocalcemia, reduces vascular permeability, exhibits antiallergic, anti-inflammatory and hemostatic effects.

In the blood it is in an ionized and bound state.

Physiological activity is inherent in ionized calcium. Deposited in bone tissue. It is excreted from the body in urine, but mainly in feces.

Insufficiency of the function of the parathyroid glands (spasmophilia, tetany), increased release of calcium from the body (in particular, with prolonged immobility), allergic diseases (angioedema, urticaria, hay fever, serum sickness), including those caused by medication; to reduce the permeability of the vascular wall (radiation sickness, hemorrhagic vasculitis), with pleurisy, pneumonia, endometritis, adnexitis; skin diseases (psoriasis, eczema, itching); for toxic liver damage, parenchymal hepatitis, nephritis; eclampsia; paroxysmal myoplegia (hyperkalemic form).

The drug Calcium chloride is used for external and internal bleeding, administered as an antidote for poisoning with oxalic acid and its salts, soluble salts of fluoric acid, magnesium salts.

It is also prescribed for complex stimulation of labor, complex treatment (in combination with antiallergic drugs) of allergic diseases.

Calcium chloride is prescribed intravenously as a stream (very slowly) and intravenously as a drip (slowly). Intravenous drip administration: ml of the drug is diluted in ml of sodium chloride, solution for injection 0.9% or

glucose, solution for injection 5%; administered at a rate of 6 drops per minute 1-3 times a day. Intravenous injection: 5 ml of the drug is administered over 3 to 5 minutes.

The duration of the course is determined by the nature, course of the disease, and the therapeutic effect achieved.

Calcium chloride, when administered intravenously, can cause bradycardia, and when administered rapidly, ventricular fibrillation.

Contraindications to the use of the drug Calcium chloride are: thrombosis and susceptibility to them, thrombophlebitis, severe atherosclerosis, hypercalcemia, childhood.

Not compatible with tetracyclines. With simultaneous use, it reduces the effect of calcium channel blockers, with quinidine - it is possible to slow down intraventricular conduction and increase the toxicity of quinidine. During treatment with cardiac glycosides, parenteral use of calcium chloride is not recommended due to increased cardiotoxic effects.

An overdose of the drug Calcium chloride can cause depression of cardiac activity and the appearance of tachycardia.

Store out of the reach of children at a temperature of 15-25°C. Shelf life - 5 years.

Calcium chloride - solution for injection.

5 ml or 10 ml per ampoule; 10 ampoules per box;

5 ml or 10 ml per ampoule; 5 ampoules in a blister; 2 blisters per pack.

1 ml of the drug Calcium chloride contains 0.1 g of calcium chloride.

Excipients: water for injection.

Calcium chloride should not be injected under the skin or into muscles, due to its pronounced irritating and necrotizing effects. When the drug is administered intravenously, the usual reaction to it appears - a feeling of heat in the mouth, and then throughout the body.

If the drug solution gets under the skin or into the muscles, if possible, suck out the calcium chloride using a syringe and inject 10 ml of sodium sulfate, 25% injection solution or 25% magnesium sulfate injection solution into the injection site. To eliminate the resorptive effect, diphenhydramine is prescribed; for hypercalcemia, EDTA is prescribed.

When prescribing the drug during pregnancy and lactation, it is necessary to weigh the expected benefit for the mother and the potential risk for the child.

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Analogues of CALCIUM CHLORIDE

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Source: http://www.medcentre.com.ua/medicamenty/kaltsiya-hlorid.html

Sodium chloride - characteristics, properties, instructions for use, side effects, interactions with other drugs

Compound

1. Isotonic (physiological) 0.9% solution containing sodium chloride – 9 g, distilled water – up to 1 liter.

2. Hypertonic 10% solution containing sodium chloride - 100 g, distilled water - up to 1 liter.

Release form

  • To dissolve medicinal substances for intramuscular and subcutaneous injections, a 0.9% sodium chloride solution is produced in ampoules of 5, 10, 20 ml.
  • For dissolving medications, intravenous drips, enemas and external use: 0.9% sodium chloride solution in bottles of 100, 200, 400 and 1000 ml.
  • For intravenous injection and external use: 10% sodium chloride solution in bottles of 200 and 400 ml.
  • For oral (inside) administration: tablets 0.9 g. To use, the tablet must be dissolved in 100 ml of boiled warm water.
  • For treating the nasal cavity: nasal spray – 10 ml.

pharmachologic effect

Indications for use

  • Restoring water balance in case of body dehydration caused by various reasons.
  • Maintaining plasma volume during surgery and after.
  • Detoxification of the body (food poisoning, dysentery, cholera, etc.).
  • Maintaining plasma volume in case of extensive burns, diarrhea, blood loss, diabetic coma.
  • Eye rinsing for inflammatory and allergic irritations of the cornea.
  • Rinsing the nasal mucosa for allergic rhinitis, nasopharyngitis, prevention of sinusitis, acute respiratory infections, after removal of polyps and adenoids.
  • Inhalation of the respiratory tract (using special devices - inhalers).

It is used to treat wounds, moisturize bandages and fabric dressings. The neutral environment of saline is well suited for dissolving drugs and co-infusion with other drugs.

1. Deficiency of the elements sodium and chlorine.

2. Dehydration due to various reasons: pulmonary, gastric and intestinal bleeding, burns, vomiting, diarrhea.

Sodium chloride - instructions for use

With long-term use of large doses of sodium chloride, it is necessary to analyze the content of electrolytes in plasma and urine.

Sodium chloride 10 - instructions for use

Sodium chloride 9 - instructions for use

Contraindications

  • increased content of sodium ions in the body;
  • increased content of chlorine ions in the body;
  • lack of potassium;
  • circulatory fluid disorders, with the possibility of cerebral and pulmonary edema;
  • cerebral edema, pulmonary edema;
  • acute heart failure;
  • intracellular dehydration;
  • extracellular excess fluid;
  • treatment with significant doses of corticosteroids.

Used with great caution in patients with changes in renal excretory function, as well as in children and the elderly.

Side effects

  • discomfort in the digestive system: nausea, vomiting, stomach cramps, diarrhea;
  • disorders of the nervous system: lacrimation, constant thirst, anxiety, sweating, dizziness, headache, weakness;
  • arterial hypertension, rapid heartbeat and pulse;
  • dermatitis;
  • menstrual irregularities;
  • anemia;
  • excess fluid content in the body or its parts (edema), which indicates a pathological shift in water-salt metabolism;
  • acidosis – a shift in the body’s acid-base balance towards increased acidity;
  • hypokalemia – a decrease in potassium content in the body’s blood.

If side effects occur, the drug should be stopped. It is necessary to assess the patient’s well-being, provide adequate assistance and save the bottle with the remaining solution for analysis.

Sodium chloride during pregnancy

1. Preeclampsia (increased concentration of sodium in the blood plasma) with severe swelling.

2. Moderate and severe stages of toxicosis.

Interaction with other drugs

Synonymous drugs for sodium chloride

  • Sodium chloride 0.9% for intravenous infusion - sterile solution in bottles.
  • Sodium chloride 1.6% for intravenous infusion.
  • Sodium chloride 12% for intravenous infusion.
  • Sodium chloride Brown (Germany) - powder for the preparation of solution for injection, solution for infusion, solution for injection, solvent for the preparation of dosage forms for injection, nasal spray.
  • Sodium chloride bufus – powder for the preparation of solution for injection, solution for infusion, solution for injection, solvent for the preparation of dosage forms for injection, nasal spray.
  • Sodium chloride-Cinco – isotonic solution for infusion, hypertonic solution, eye drops and eye ointment.
  • Sodium chloride – 0.9% solution for infusion (Bulgaria).
  • Salorid – 0.9% solution for infusion (Bangladesh).
  • Rizosin – 0.65% nasal spray with and without menthol.
  • Salin – 0.65% nasal spray (India).
  • No-salt – 0.65% nasal spray.
  • Physiodose – 0.9% solution for topical use.

Additional Information

1. Remove container from outer packaging immediately before use. It protects and maintains the sterility of the drug.

2. Squeeze the container tightly and check for integrity. If damage is found, discard the container, as the solution in it is dangerous.

3. Check the solution visually: for transparency, absence of impurities and inclusions. If present, discard the container.

4. Hang the container on a tripod, remove the plastic fuse and unscrew the lid.

5. Add medications into the solution following aseptic rules. Move the clamp that regulates the movement of the solution to the “closed” position. Disinfect the area of ​​the injection container, make a puncture in it with a syringe and inject the drug. Mix well. Move the clamp to the “open” position.

Storage conditions and expiration dates

  • powder and tablets - without restrictions;
  • 0.9% solution in ampoules – 5 years;
  • 0.9% solution in bottles – 12 months;
  • 10% solution in bottles – 2 years.

Do not use after expiration date. Before using any drug containing sodium chloride, you should consult your doctor.

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Source: http://www.tiensmed.ru/news/natriahlorid-ec7.html

Calcium chloride - instructions for use. Indications for taking calcium chloride orally, in injections or for the face

Modern medicine does not pamper consumers with inexpensive medicines. Calcium Chloride is an exception. The cheap drug will come to the rescue for various ailments; it is used in industry and cosmetology, proving its versatility.

What is calcium chloride

Calcium Chloride has the chemical formula CaCl2. To understand what calcium chloride is and how it works, you need to look at its properties. It has an orthorhombic crystalline molecular form. The substance turns into a hexahydrate - solid in structure, then becomes liquid. Calcium chloride is obtained under technical conditions during the production of soda or Berthollet salt. The second recipe: the interaction of hydrochloric acid and calcium carbonate or hydroxide. The powder dissolves in acetone or lower alcohols and absorbs water, cooling it.

Calcium chloride - instructions for use

The drug is widely used in medicine. The release form is a colorless liquid in ampoules. Indications prescribe its use intravenously, orally or by electrophoresis. The use of calcium chloride, according to the instructions, is beneficial for certain ailments:

  • for allergies and complications associated with reactions to other medications;
  • calcium deficiency in the body;
  • for bronchial asthma;
  • hay fever;
  • toxic pulmonary edema and other inflammatory processes;
  • radiation sickness;
  • for eczema;
  • hepatitis;
  • jade;
  • for psoriasis;
  • has a diuretic effect, like ammonium chloride;
  • for bleeding of various origins (to increase coagulation);
  • to relieve symptoms of poisoning;
  • For topical use, electrophoresis is used with this substance, which has an astringent, anti-inflammatory, strengthening and soothing effect.

You can find the product freely available in any pharmacy. However, administering the drug orally without a doctor’s prescription and supervision is strictly prohibited, as this can cause significant harm to health. At home, the medicine can be used to make cosmetic products: masks, scrubs, added to shampoos or balms.

Calcium chloride intravenously

The drug can be administered by injection or dropper. To use calcium chloride intravenously, the prescribed amount of medication should be diluted from an ampoule of glucose ml or sodium chloride solution (0.9%). Before injecting the resulting liquid into the blood, you need to warm it up to human body temperature. The procedure should be done slowly; increasing the speed can cause vascular damage and cardiac arrest.

The administration process can be characterized by a decrease in blood pressure, nausea, a chalky taste, fever (that’s why the procedure is called a “hot injection”), fainting, and arrhythmia. If the patient begins to feel pain or redness appears on the skin, use of the drug should be stopped immediately. After the procedure, the patient requires a twenty-minute rest under the supervision of a doctor.

Calcium chloride intramuscularly

It is impossible to find a solution of this injection on pharmacy shelves. This fact is explained by the fact that administering calcium chloride intramuscularly or subcutaneously is strictly prohibited. This procedure can lead to the following consequences:

  • severe irritation;
  • necrosis and tissue death at the injection site.

Calcium chloride for oral administration

Intravenous administration is not recommended for some categories of citizens, for example, children. Calcium chloride for oral administration is suitable for such people. Adults should take 1 tbsp. l. twice a day after meals. Children are prescribed calcium chloride 1-2 tsp orally. after meal. If the drug enters the digestive system, it can cause heartburn and pain in the epigastric region.

Peeling with calcium chloride at home

This medical product in liquid form is used in cosmetology to get rid of impurities and dead skin cells, and acne. Cleansing your face with calcium chloride at home - step-by-step instructions:

  1. The first step should be to cleanse your face of makeup.
  2. On cleansed skin, apply foam from baby soap that does not contain fragrances or other harmful additives.
  3. Take a small container and pour the contents of the calcium chloride ampoule inside. Gradually apply the product onto your face with your fingers. Rub lightly until lumps form. Do not apply to the areas around the eyes and lips.
  4. After small lumps have formed, continue the massage for a short time with light movements until creaking appears.
  5. To remove the remaining product from your face, use a napkin, then wash with warm water.
  6. Upon completion of the procedure, treat your face with moisturizer.

Calcium chloride for hair

If you have problems with your hair, experts recommend saturating your usual products with useful substances or making masks with them. You can buy the necessary medications at the pharmacy. Calcium chloride for hair is an excellent help for severe hair loss, strengthens it and stimulates growth. The medicine should be used separately from other vitamin medications. You can use it by adding a small amount to shampoo and conditioner or homemade masks. The treatment procedure is required twice a week, in a course of sessions.

A simple mask using this drug:

  1. Take a small bowl, add 1 tbsp. l. balm or hair mask that you are used to using.
  2. Pour the calcium chloride ampoule inside and stir the ingredients until smooth.
  3. Apply the substance to damp and clean hair, put on a plastic cap, and wrap a towel on top. Leave it to work for a minute.
  4. Rinse off the product with warm water.

Calcium chloride - contraindications

It is better to coordinate any use of the drug with your doctor, since the medicine may be harmful. Calcium chloride – contraindications:

  • severe atherosclerosis;
  • the child should not be given the drug intravenously;
  • tendency to form blood clots;
  • calcium levels in the blood are higher than normal;
  • If you are using a peeling product, you should not sunbathe for a couple of days after the procedure.

Calcium chloride price

A transparent solution for intravenous injection can be purchased in Moscow pharmacies or bought in an online store from a catalog without leaving home. Prices for medications do not differ significantly. The indicator depends on the volume of ampoules and the manufacturer. However, before you order online, make sure you don't have to pay shipping costs. The approximate price of calcium chloride is shown in the table.

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Video: peeling with calcium chloride at home

Reviews

I learned what calcium chloride is after an unsuccessful visit to the dentist. At home I discovered that there was blood coming from my gums. How to stop it, I asked the doctor. The doctor advised me to purchase this drug because it affects blood clotting. I was able to buy it inexpensively, and I only had to drink 1 spoon for the bleeding to stop.

Since I was a teenager, I have suffered from oily skin and enlarged pores. A soap scrub with a 10% solution of this medicine helps me get myself in order. I learned about this Hollywood cleaning method from a friend’s review. The procedure is much cheaper, since the composition has a reasonable price, and I am very pleased with the result.

Alexey, 32 years old

I first saw this name in a review about the treatment of pneumonia. Having fallen ill myself, I tried to use it on the doctor’s advice. I was given injections into a vein. The cough went away quickly - within a few days. The specialist explained that the properties of the product perfectly help eliminate inflammation. I was surprised by its price. Today you rarely see medicines under 50 rubles.

The information presented in the article is for informational purposes only. The materials in the article do not encourage self-treatment. Only a qualified doctor can make a diagnosis and make recommendations for treatment based on the individual characteristics of a particular patient.

Source: http://sovets.net/9364-chlorid-kalciya.html

Calcium chloride solution

For normal functioning, our body must receive all the substances it needs in full. For example, a chronic lack of an element such as calcium can cause significant harm to the body, for example, disorders in bone tissue, a decrease in the speed of transmission of nerve impulses, disturbances in heart rhythm and blood clotting processes, and the development of osteoporosis.

Unfortunately, there is not enough calcium in our daily diet, which is why many patients are advised by doctors to take medications based on it. Since calcium in its pure form is practically not absorbed by the human body either as an injection or orally, it must be taken in combination with soluble salts.

The most popular of these drugs is calcium chloride, in pharmacology called calcium chloride. The pharmaceutical industry produces it in the form of a solution, which can be administered as an intravenous injection, and also, if necessary, taken orally. To buy calcium chloride at a pharmacy for use at home, you do not need a prescription.

Composition of the drug and its release form

Calcium chloride is available as a colorless, clear liquid for intravenous administration. The solution contains 100 mg of calcium chloride per 1 ml.

Indications for use

Calcium chloride not only has a very beneficial effect on the functioning of all body systems, its intake can also prevent tissue inflammation and increase resistance to various types of infections, which helps minimize the harm that they can cause to the human body. So the possibilities for using this drug in medicine are very numerous.

Most often, calcium supplements are prescribed for the following indications:

  • Treatment of hepatitis and nephritis;
  • Various dermatological diseases;
  • Increased human need for calcium;
  • Poisoning with magnesium and fluorine salts, as well as oxalic acid;
  • Being immobilized for a long time;
  • Weakness of labor;
  • Allergies (eg, hay fever, urticaria, allergic dermatosis);
  • Acute blood loss due to pulmonary, uterine, gastrointestinal and nasal bleeding;
  • Postoperative period.

Calcium chloride is also used for washing wounds and mucous membranes of the eyes at home, and is part of solvents for various pharmacological drugs.

Contraindications for use

  • Chronic renal failure;
  • Tendency to thrombosis;
  • Urolithiasis disease;
  • Severe atherosclerosis;
  • Simultaneous use of cardiac glycosides with it (the use of calcium chloride is not recommended, as the cardiotoxic effect of the drugs is enhanced);
  • Hypersensitivity to the components of the drug;
  • Sarcoidosis;
  • Pregnancy, as well as the period of lactation - breastfeeding (if taking calcium chloride is necessary during lactation, breastfeeding is stopped).

Taking calcium chloride does not affect the ability to drive in any way.

Methods of use

Instructions for use of calcium chloride indicate that the drug can be used in different ways. It can be administered intravenously (drip or stream) or taken orally, it is also possible to introduce it into the body using electrophoresis through the skin - direct contact of the drug into the muscle or subcutaneous tissue can cause significant harm to health - severe local irritation and even necrosis of surrounding tissues.

In cases where intravenous administration of the drug is prescribed, calcium chloride must be diluted in 100 - 200 ml with a five percent solution of dextrose (glucose) or a 0.9 percent solution of sodium chloride.

The resulting solution is heated to body temperature before being introduced into the blood. The injection is given slowly - no more than 0.75 - 1.5 ml (that is, a maximum of 8 drops) per minute. If the injection is given quickly, significant harm can be caused to the cardiovascular system, including cardiac arrest.

When calcium chloride is administered intravenously, the patient feels heat throughout the body (popularly this procedure is called a “hot injection”) and a chalky taste in the mouth. Also, a decrease in blood pressure, nausea, arrhythmia and fainting are possible.

If during the procedure there is redness at the injection site or the patient feels pain, the administration of the drug must be stopped.

After the injection is given, the patient should remain for some time (no more than 20 minutes) under the supervision of a doctor in a lying position. Usually up to 3 ampoules of the product are administered in one injection.

Typically, intravenous calcium chloride is prescribed only to adults. The child should take the calcium chloride solution exclusively orally.

Calcium chloride solution should be drunk after meals, the maximum daily dose, which in no case should be exceeded, for children - 15 milliliters (0.3 ml per 1 kg of weight), so as not to cause harm by overdose of the drug, and for adults - 10 - 15 milliliters of product. As a rule, a five or ten percent solution of the drug is prescribed for internal use.

Storage conditions and expiration dates

The shelf life of calcium chloride is 5 years if stored properly, including at home - in a dark place at an air temperature of no more than 25 degrees.

Although calcium chloride is freely sold in pharmacies, and each package with the drug contains instructions that indicate all doses, contraindications, composition, and possible harm if used incorrectly, it is still not recommended to take it for treatment at home on your own. At home, you can use calcium chloride solution only for external use, so as not to harm your health.

Source: http://wmedik.ru/lekarstva/rastvor-xloristogo-kalciya.html

Calcium chloride

Description current as of 02/18/2017
  • Latin name: Calcium chloride
  • ATX code: B05XA07
  • Active ingredient: Calcium chloride
  • Manufacturer: JSC Dalkhimfarm; NPO FSUE "Microgen"; OJSC "Novosibkhimpharm"; JSC "Sintez"; JSC "Biokhimik" (Russia), etc.

Compound

1 ml of Calcium Chloride injection solution includes 100 mg of calcium chloride diluted in water for injection.

Release form

Medical calcium chloride is produced in the form of an intravenous injection solution in ampoules of 2 ml; 5 ml or 10 ml No. 10 per package.

pharmachologic effect

Detoxification, anti-inflammatory, antiallergic, hemostatic, reducing capillary permeability.

Pharmacodynamics and pharmacokinetics

Calcium chloride, also known as calcium chloride (chemical formula CaCl2), can be a granular powder (colorless rhombic crystals), used in the food and technical industries, or a liquid solution in injection water (intravenous, drinking), used in medicine and cosmetology. This product is obtained during the ammonia soda production process, where it is released as a by-product, as well as during the production of bertholite salt.

Calcium chloride is highly hygroscopic with vigorous absorption of water vapor and the formation of solid hydrates, which are subsequently converted into liquid. Crystals of this substance dissolve well in water, liquid ammonia, lower alcohols and acetone. Calcium itself is one of the main elements of the periodic table, and therefore the use of calcium chloride covers many aspects of human life.

Technical calcium chloride (GOST) is used as a desiccant for various liquids and gases, a deicing agent, an antifreeze additive, and a cement hardener. The use of technical CaCl2 is practiced in the chemical, woodworking/forestry, oil/refining, metallurgical, gas processing industries, construction and in the production of refrigeration equipment.

This substance is also useful in the manufacture of various food products, for which calcium chloride (GOST R4) is used in the form of food additive E509. This additive is used in the production of bread (as a preservative), soft and low-alcohol drinks (as a water hardness regulator), low-calorie jellies (as a thickener), dairy products (as a clot former), during storage and transportation of meat (as a lamb and beef softener).

In turn, CaCl2 has found its use in medicine as a therapeutic agent that replenishes calcium deficiency, a vital element without which normal transmission of nerve impulses, bone formation, contraction of smooth and skeletal muscles, adequate blood clotting and myocardial contractility are impossible. Thanks to this element, the likelihood of developing inflammatory phenomena decreases, vascular and cellular permeability decreases, the human body’s resistance to various infectious diseases increases, and phagocytosis (reduced after the use of sodium chloride) increases.

In the case of intravenous administration of the medicinal drug CaCl2, activation of the sympathetic part of the autonomic nervous system, an increase in the production of epinephrine by the adrenal glands and some diuretic effect are observed. It can be used as a hemostatic and antiallergic agent. When interacting with fluoric, oxalic acids and magnesium salts, insoluble compounds are formed, which are used in antidote therapy.

The main part of the therapeutic agent accumulates in bone tissue. Approximately 45% of CaCl2 is found in plasma in the form of complex protein compounds. Excretion is 20% by the kidneys and 80% by the intestines. Approximately 95% of the drug excreted by glomerular filtration undergoes reabsorption in the renal tubules (proximal and distal), as well as in the ascending limb of the loop of Henle.

Indications for use of Calcium Chloride

Indications for intravenous and oral CaCl2 include:

The main indications for the use of a hot injection of Calcium Chloride (jet intravenous injection) include:

  • acute allergic reactions;
  • bleeding;
  • severe cases of poisoning with fluoric, oxalic acids and magnesium salts;
  • other indications described above in case of impossibility of infusion.

Contraindications

Contraindications to the use of Calcium chloride, including contraindications to a hot injection of this drug, are:

Side effects

When using Calcium Chloride, the following may sometimes occur:

Calcium chloride, instructions for use

The instructions for Calcium Chloride allow for its intravenous and, in some cases, oral use. Whether it is possible to take ampoules for allergies, hypocalcemia and other indications is decided by the attending physician on an individual basis.

IV administration should be carried out in the form of slow infusions (6-8 drops per minute) of 5-10 ml of a 10% solution of the drug diluted with sodium chloride (0.9%) or glucose (5%). It is also practiced to use the drug in the form of a very slow intravenous injection (1 ml per minute), for which calcium chloride in a volume of 5 ml is injected intravenously over 5 minutes.

Instructions for the use of Calcium Chloride orally recommend taking a 5-10% solution 2-3 times a day after meals, in dosages equal to ml for adult patients and 5-10 ml for children.

  • 10% calcium chloride for allergies (allergic dermatoses, Quincke's edema, insect bites, urticaria, etc.), lead colic, magnesium overdose is prescribed in a dose of 7.5-15 ml. How to take CaCl2 for allergies is decided solely by the attending physician. As a rule, the drug is prescribed in the form of an infusion or jet injection (depending on the severity of the condition). Oral use of this medicinal product is practiced only in cases of mild allergic manifestations and in complex treatment, therefore it is not advisable to drink it in case of severe allergies.
  • When transfusing citrated blood or exchange transfusion, adults/children are prescribed 0.3 ml of a 10% solution of the drug per 100 ml of blood.
  • In case of severe magnesium intoxication, adults practice jet injection of 5 ml of a 10% solution under strict supervision of the patient’s condition until it is completely restored to normal before subsequent administration.
  • For hypocalcemia, adults are recommended to inject 5-10 ml of a 10% solution of the drug with an interval of 1-3 days. The interval between infusions is determined depending on the observed plasma calcium level and the patient's individual response to the administered drug.
  • Therapy for tetany in adult patients requires infusion of 10 ml of a 10% solution over minutes, with the possible repetition of the infusion after 6 hours.
  • In case of hyperkalemia occurring with impaired cardiac function on the ECG, the dosage of the drug is selected individually and depends on the observed condition of the patient. IV administration is carried out under the control of a cardiogram.

The dosage for elderly patients is the same as for adult patients.

For pediatric patients, the drug is prescribed when they reach the age of 12 months. The maximum daily dosage for children (regardless of age) is 10 ml of a 10% solution.

  • For hypocalcemia in children, a slow infusion of 0.1-0.2 ml of a 10% solution per kilogram of the child’s weight is prescribed at a rate of up to 0.5 ml per minute. It is possible to repeat the infusion every 4-6 hours.
  • Treatment of tetany in children proceeds with the introduction of 0.1 ml of a 10% solution per kilogram of the child’s weight for 5-10 minutes. If necessary, repeat injections after 6 hours.

In addition to the use of an injection solution of Calcium Chloride in medicine, it is also used in cosmetology (peeling the face with calcium chloride at home or in beauty salons), as well as for the production of calcined cottage cheese.

Calcium chloride, facial peeling

Calcium chloride is used for the face to cleanse it of dead skin and comedones (blackheads). Naturally, such a procedure is best carried out in a beauty salon, where a trained cosmetologist will not only perform this operation correctly, but will also help avoid possible negative reactions. The main factors in achieving a positive and harmless result of such peeling are the accuracy of dosing of the drug and the absence of allergic reactions in the patient to its ingredients. If you are absolutely sure that you are not allergic to the components of the CaCl2 solution, you can try to carry out the facial cleansing procedure yourself at home.

This peeling is more suitable for people with an oily facial skin structure, although even with dry skin, the cleansing procedure can be completed without any complications. The optimal time for this procedure is the evening before the weekend. It should be remembered that any peeling involves micro trauma to the skin, so some redness of the skin after the procedure is a normal reaction of the body and, provided that regenerative products are used for facial skin after peeling, it will pass very quickly.

Before you start peeling, you need to remember a few rules to obtain the optimal result of this procedure and prevent its possible negative consequences.

  • Avoid applying CaCl2 solution to particularly sensitive areas of the face (the area above the upper lip and around the eyes).
  • If you experience a sharp burning sensation when applying the solution to the skin (a possible sign of an allergic reaction), you should wash it off immediately and consult a cosmetologist or doctor. To avoid such incidents, you must first test the body's reaction to Calcium Chloride on a small area of ​​skin on the forearm.
  • After washing your face following the peeling procedure, you should not dry yourself with a towel (you must give your facial skin the opportunity to absorb moisture). The last rinse is best done with a decoction of herbs, mineral water, chamomile, rose or lavender hydrosol.
  • Do not forget that the impact of any chemical peeling is equivalent to a mild chemical burn, and therefore it is necessary to strictly adhere to the time frame for this procedure.
  • It should be remembered that frequent use of chemical peels can cause premature skin aging and the development of inflammatory phenomena due to a decrease in epidermal barrier functions. To prevent such consequences, post-procedure facial skin care is necessary using moisturizing oils and other natural hypoallergenic cosmetics.

You should refrain from peeling using CaCl2 if:

  • frequent allergic manifestations of unknown etiology;
  • too dry and sensitive facial skin;
  • the presence of inflamed skin areas in the area of ​​the procedure.

Stages of the peeling procedure

To carry out one procedure for cleaning the facial area at home, you need to prepare: 1 ampoule with a 10% solution of Calcium Chloride, 1 piece of baby toilet soap (without fragrances and fragrances) and cotton pads.

  • Before the procedure itself, you should thoroughly clean and dry your facial skin.
  • Carefully open the ampoule with the CaCl2 solution and moisten the prepared cotton pad with it.
  • Apply the solution onto problematic facial skin with light movements and let it dry. Repeat this procedure several times until the entire contents of the ampoule are used.
  • Generously apply (soap) baby soap onto a cotton pad and wipe the treated skin surfaces with it using hand massage movements (when soap and CaCl2 solution interact, a reaction should occur to form flakes), thus rolling dead skin and the contents of comedones into small lumps.
  • After finishing the peeling procedure, wash your face thoroughly with warm water, treat the skin with chamomile, rose or lavender hydrosol and let it dry on its own.
  • After the skin has absorbed moisture, apply a moisturizer or soothing mask to the slightly damp surface.

Reviews from cosmetologists about peeling with calcium chloride recommend carrying out such cleaning no more than once a week, after consulting with a dermatologist or professional cosmetologist.

Recipe for cottage cheese from Calcium Chloride

Calcined cottage cheese is an excellent source of calcium, which is vital for the human body, especially for the normal formation and further longevity of bones and teeth. Thus, eating this product will be extremely beneficial for the growing body and the body of older people.

  • To prepare calcined cottage cheese, you should heat raw milk (cow or goat) to approximately 40°C, then, continuously stirring the warm milk, carefully pour a 10% CaCl2 solution into it in the proportion of 1-1.5 tablespoons of the medicinal product per 0.5 liters of milk (more Calcium Chloride will give the cottage cheese a bitter taste). Then you need to bring the milk almost to a boil, until it curdles, remove the pan from the stove and cool. To separate the whey, use a sieve lined with a double layer of gauze, onto which the curdled mass is folded.
  • Another popular recipe for making calcined cottage cheese is a mixture of 2 tablespoons of a 10% CaCl2 solution, 1 liter of milk and 1 liter of kefir. To prepare such cottage cheese, mix milk and kefir (1l/1l) in one pan and heat them without stirring over low heat. After the curdled flakes appear, you need to add Calcium Chloride (2 tbsp) to the mixture of dairy products and, without bringing the curdled mass to a boil, remove the pan from the stove, cool slightly and remove the curd using a slotted spoon, squeezing it a little on the edge of the pan.

The daily intake for cottage cheese with extra calcium is 100 grams. It is not recommended to increase the portions of this product due to a possible disruption of mineral metabolism in the body. In addition, you can store such cottage cheese in the refrigerator for no more than 2-3 days, and it is best to eat it no more than 2-3 times a week.

Overdose

The use of excessive amounts of Calcium Chloride can cause suppression of cardiac activity, the development of tachycardia, and a decrease in blood pressure. In addition, with an overdose of CaCl2 solution, the formation of a hypercalcemic crisis with manifestations of nausea/vomiting, muscle weakness, anorexia, polyuria, constipation, polydipsia, abdominal pain, arthralgia, mental disorders, nephrolithiasis, and drowsiness is possible. In severe cases, the development of arrhythmia or even a coma may occur.

As a treatment for the negative manifestations described above, it is practiced to prevent further intake of calcium into the body from the outside and carry out symptomatic treatment.

Interaction

Due to the increased risk of hypercalcemia, calcium chloride should not be coadministered with vitamin D or thiazide diuretics.

Co-administration of the drug with Ceftriaxone should be avoided. It is unacceptable to mix or simultaneously administer ceftriaxone with calcium-containing injection solutions, even if they are administered into different veins and when using different infusion systems. If there is an urgent need to use these two drugs, their sequential administration is allowed, subject to infusion in different places or when replacing the infusion system.

It should be remembered that Calcium Chloride reduces the cardiotonic effects of Dobutamine.

Calcium preparations may reduce the bioavailability of Phenytoin, the effectiveness of calcium channel blockers and the effect of Calcitonin in hypercalcemia.

During therapy with cardiac glycosides, due to increased cardiotoxic effects, parenteral administration of calcium chloride should be avoided.

Parallel use with Quinidine may increase its toxicity and slow down intraventricular conduction.

Combined use with other drugs containing calcium or magnesium increases the risk of hypercalcemia or hypermagnesemia, especially in patients with diagnosed CHF.

Calcium chloride can reduce the effects of depolarizing muscle relaxants and increase the duration of action of tubocurarine chloride.

Terms of sale

Calcium chloride is available from pharmacies with a prescription.

Storage conditions

Ampoules with CaCl2 solution can be stored at air temperatures up to 25°C.

Best before date

The healing properties of the injection solution are maintained for 5 years.

special instructions

In the case of prolonged use of high doses of CaCl2 injection solution, the formation of hypercalcemia with the deposition of calcium salts in the body is possible.

Before use, the injection solution must be warmed to the patient’s normal body temperature.

To prevent the damaging effect of the drug on the vascular walls, injection should be carried out into a large vein using a thin needle.

Due to the strong irritating and necrotizing effects of the drug, it is unacceptable to administer calcium chloride intramuscularly or subcutaneously. If a CaCl2 solution gets into muscle tissue or under the skin, it is necessary to extract it as much as possible using a syringe and inject 10 ml of a 25% sodium sulfate injection solution or 5-10 ml of a 25% magnesium sulfate injection solution into the injection area.

In order to prevent the resorptive effect of the drug, Diphenhydramine can be prescribed, and in case of hypercalcemia, EDTA preparations can be used.

It should be remembered that the intravenous administration of a CaCl2 solution is accompanied by a feeling of heat in the oral cavity, which subsequently spreads throughout the body, which is a normal reaction of the human body to this drug.

During therapy, careful monitoring of plasma calcium levels is necessary.

Careful administration of Calcium Chloride is required for patients with kidney pathologies, dehydration, nephrolithiasis, electrolyte imbalance (risk of hypercalcemia), heart disease (risk of arrhythmia), painful conditions occurring with hypercalcemia (including sarcoidosis and malignant neoplasms), respiratory acidosis, “pulmonary” heart , respiratory failure (risk of toxic manifestations due to CaCl2 oxidation).

Due to possible severe gastrointestinal irritation, injectable Calcium Chloride should not be administered orally to children.

Due to the possibility of sediment formation, mixing CaCl2 solution with ceftriaxone in one injection should not be allowed.

Analogs

  • Sodium chloride;
  • Gluxil;
  • Soda Buffer;
  • Xylate;
  • Magnesium Sulfate;
  • Lactoxyl;
  • Sodium Bicarbonate;
  • Plerigo;
  • Reamberin;
  • Sorbilact;
  • Console;
  • Rheosorbilact;
  • Cormagnesin;
  • Potassium chloride;
  • Custodiol.

For children

For pediatric patients, the drug is prescribed when they reach the age of 12 months, taking into account the maximum permissible daily dose of 10 ml.

For hypocalcemia in children, a slow infusion of 0.1-0.2 ml of a 10% solution per kilogram of the child’s weight is prescribed at a rate of up to 0.5 ml per minute. It is possible to repeat the infusion every 4-6 hours.

Treatment of tetany in children proceeds with the administration of 0.1 ml of a 10% solution per kilogram of the child’s weight for 5-10 minutes. If necessary, repeat injections after 6 hours.

Due to the potential for severe gastrointestinal irritation, injectable Calcium Chloride should not be administered orally to children.

During pregnancy (and lactation)

Prescribing a solution of Calcium Chloride during pregnancy is allowed if there is an objective need for its use, with extreme caution and under the control of plasma calcium levels and other indicators.

The use of CaCl2 injection solution during breastfeeding is not contraindicated.

Reviews

For the most part, reviews of calcium chloride for allergies, hypocalcemia, titanium, various bleeding, dermatological problems and other indications inherent in this drug are positive. Patients who use Calcium Chloride solution on the recommendation of a doctor speak not only of its sufficient effectiveness and the virtual absence of side effects (if dosages are observed), but also of the cheapness of this drug, which is also very important in our time. Naturally, modern medicine today has in its arsenal therapeutic agents that are much superior to the effect of a CaCl2 solution, which can cope with the illness that besets the patient much faster, but such drugs are also much more expensive. Therefore, in cases where the choice of medications depends on the patient’s ability to pay, and the attending physician allows the possibility of using Calcium Chloride in therapy and is confident in its effectiveness for the observed disease, this drug can be an excellent alternative to expensive treatment.

Reviews from cosmetologists about facial peeling with Calcium Chloride are ambiguous and cautious, but provided that all the above-described precautions for the external use of the drug for the face are observed, they are, in principle, positive and confirmed by numerous positive testimonies from women who have tried this cleansing method.

Price for Calcium Chloride, where to buy

The price of Calcium Chloride in ampoules in Russian pharmacies is almost the same in all regions and therefore there is practically no difference where to buy Calcium Chloride in a pharmacy in St. Petersburg (St. Petersburg), in Moscow or, for example, in Yekaterinburg. Today in the pharmacy the price for a solution of Calcium Chloride 10% is rubles for 10 ampoules of 5 ml and rubles for 10 ampoules of 10 ml.

The price of technical and food grade calcium chloride varies widely from 15 rubles to 120 rubles per 1 kilogram.

Education: Graduated from Vinnitsa National Medical University. N.I. Pirogova, Faculty of Pharmacy, higher pharmaceutical education – specialty “Pharmacist”.

Work experience: Worked in the pharmacy chains “Konex” and “Bios-Media” with the specialty “Pharmacist”. Work as a Pharmacist in the Avicenna pharmacy chain in the city of Vinnitsa.

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Svetlana: I constantly go on diets, and because of this I have problems with stool. Girlfriend for me.

Lily: And if it’s a thorn, can you drip some drops?

Gray: Tablets are effective, I didn’t think that only tablets would help me restore my .

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Source: http://medside.ru/hloristyiy-kaltsiy