Fluimucil antibiotic or not

Posted on by admin

Fluimucil - IT antibiotic

Description current as of 05/16/2014

  • Latin name: Fluimucil – antibiotic IT
  • ATX code: J01BA02
  • Active ingredient: Thiamphenicol glycinas acetylcysteinas (Thiamphenicol glycinas acetylcysteinas)
  • Manufacturer: Zambon, Italy

Compound

One bottle contains: glycinate acetylcysteinate thiamphenicol – 0.81 g, including thiamphenicol 500 mg; additional substance – disodium edetate; water as a solvent.

Table of contents:

Release form

Powder obtained by lyophilization, from which a solution is prepared; in bottles complete with solvent, 3 pcs. in a pack.

pharmachologic effect

The substance is a combination of an antibiotic and a mucolytic drug.

Thiamphenicol has a wide spectrum of action on bacteria that cause respiratory tract infections - both gram-positive (streptococci, clostridia, staphylococci) and gram-negative (neisseria, Haemophilus influenzae, salmonella, yersinia, E. coli).

Acetylcysteine ​​actively dilutes sputum and purulent discharge, promotes sputum discharge, reducing viscosity.

Acetylcysteine ​​promotes better penetration of thiamphenicol into the lung tissue and prevents the adhesion of microorganisms to the mucous membrane of the respiratory system.

Pharmacodynamics and pharmacokinetics

Thiamphenicol accumulates in the respiratory tract, and maximum concentration occurs within 1 hour after injection into the muscle. The half-life is 3 hours, excreted in the urine.

Acetylcysteine ​​accumulates in the intercellular space, bronchial secretions, lung tissue, liver and kidneys. Half-life – 2 hours; excreted by the kidneys, and a small part through the intestines.

The drug penetrates the placenta.

Indications for use

  • damage to the ENT organs and upper respiratory tract (sinusitis, otitis, laryngotracheitis);
  • diseases of the lower respiratory system (bronchitis, lung abscess, pneumonia, bronchiectasis, cystic fibrosis, emphysema, whooping cough, bronchiolitis);
  • treatment and prevention of infectious and obstructive complications after tracheostomy, thoracic surgery (atelectasis, bronchopneumonia);
  • preparation for aspiration of bronchial secretions and bronchoscopy;
  • in order to improve drainage in case of concomitant pulmonary infections (including tuberculosis, the presence of cavernous lesions).

Contraindications

  • diseases and changes in blood count (leukopenia, anemia, thrombocytopenia);
  • individual intolerance to substances included in the drug.

Kidney function in children of the first 2 years of life has features associated with age, therefore, in them, as well as in patients with severe damage to the liver and kidney functions, the drug must be used with caution.

Side effects

Allergic reactions.

When injected into a muscle, there may be a burning sensation at the injection site; rarely leukopenia, thrombocytopenia, anemia, neutropenia, reticulocytopenia.

Using the antibiotic Fluimucil for inhalation can cause irritation of the respiratory mucosa, reflex cough, nausea, and rhinitis. Sometimes bronchospasm occurs, and bronchodilators should be used.

Instructions for use Fluimucil - IT antibiotic (Method and dosage)

Use intramuscularly in the dose:

  • for adults, it is administered daily in 3 doses;
  • children under three years of age 125 mg twice daily;
  • children from 3 to 7 years mg twice a day;
  • for children: 750 mg per day, divided into 3 injections.

For newborns up to 2 weeks, as well as premature infants, use a dose of 25 mg/kg body weight per day.

How to dilute for inhalation?

For adults, 500 mg of dry substance is dissolved in 4 ml of water for injection and divided into 2 doses per day (2 ml each). Inhalations for children are prepared in the same amount of water for injection as for adults (4 ml), dissolving 250 mg of powder and also used twice a day.

Locally for washing the paranasal sinuses, incl. after surgical interventions, for endotracheal administration through a tracheostomy, bronchoscope or endotracheal tube, the powder is dissolved using water for injection in an amount of 4 ml, 500 mg for adults and 250 mg for children.

For otitis and diseases of the nasopharynx, 2-4 drops are instilled into the nasal passage or ear canal.

In case of appropriate indications, the dose of the drug can be doubled.

In newborns, premature and elderly patients, do not increase the dose.

The instructions for the antibiotic determine the course of treatment with the drug for no more than 10 days.

Overdose

Possible increased side effects of the drug, superinfection, disturbances of the bacterial flora. Symptomatic therapy is used as treatment.

Interaction

If you use cough suppressants, mucus stagnation may occur.

It is not recommended to mix the inhalation antibiotic Fluimucil with other substances in an aerosol.

Terms of sale

Storage conditions

Away from children and at temperatures between 15 and 25°C.

Best before date

special instructions

During the treatment period, constant monitoring of the blood count is necessary. If the number of granulocytes and leukocytes decreases, the drug should be discontinued.

Avoid contact of the solution with rubber and metal surfaces.

Analogs

It has no analogues.

For children

Use with great caution in children under two years of age, due to age-related characteristics of kidney function.

During pregnancy and lactation

Prescribe only when the benefit to the woman outweighs the risk to the fetus. During breastfeeding, if treatment is necessary, feeding should be stopped.

Reviews about Fluimucil – IT antibiotic

On many medical forums, there are reviews about Fluimucil, an antibiotic, usually from young mothers who used this antibiotic for inhalation for children. They note a quick effect - literally within 3-4 days the child’s condition improves. Those who have tried the drug at least once prefer it when they get sick again. It is very good to use the drug for a nebulizer - both convenient and effective.

Price Fluimucil – IT antibiotic, where to buy

In Russia, the price of Fluimucil-antibiotic IT ranges from 413 to 605 rubles.

The average price of Fluimucil for inhalation in Moscow is about 538 rubles. In Ukraine, the drug can be purchased for 174 UAH.

Hello! The doctor prescribed the child inhalations with the antibiotic fluimucil, but did not describe in what proportions. Do I need to add saline and if so, how much? The child is almost 3 years old. Cough and sore nasopharynx. Thank you in advance.

Fluimucil is an antibiotic. It greatly irritates the respiratory tract. My throat breaks after it. My throat hurts and stings from it. And my nose too. I don’t know if I still need it. For now I try it once a day. I seem to have bronchitis in the acute phase. Sputum. green. .but now it’s not like that anymore. A little lighter.

715 RUR bought on March 30, 2016 in a pharmacy next to Alpha Bank on the lands of Lipetsk

She was treating bronchitis (against the background of bronchial asthma). On the second day, a good effect from the inhalations was already noticeable. Great: fast, high quality, affordable.

My son is three years old, and his ENT doctor prescribed inhalations as follows: we dilute one injection bottle of water with 500 mg of powder. Then pour 3 ml of saline solution and 1 ml of the resulting solution into the inhaler. We inhale for 10 minutes, twice a day. One diluted ampoule is enough for 2 days. Store in the refrigerator. We are treated for six days. Snot and cough go away.

There is 500 mg of powder in a bottle, 4 ml of water in an ampoule - this is a dose for an adult for 2 doses. I have a question. Is it possible to dilute 500 mg in 8 ml of water and use it in 4 doses for a child? If possible, where and for how long should the solution be stored? In a refrigerator? And how to avoid contact of the solution with metal and rubber if you draw the solution with a syringe with a NEEDLE and the stopper of the bottle is RUBBER. Thank you.

I have asthma, COPD, emphysema. The doctor prescribed Fluimucil antibiotic inhalation through a nebulizer. During inhalation, severe suffocation occurred. Should I continue doing inhalations?

please tell me, my husband has sinusitis, but it bothers him when he is sick, but otherwise, can fluimucil-antibiotic IT help? Thanks in advance)

The drug helped us. We did inhalations for 5 days.

Alice, please tell me how old your child is, and in what proportion the antibiotic fluimucil should be diluted for inhalation. We were also prescribed it, our daughter has obstructive bronchitis, but I didn’t understand how to dilute it, with the water in the box or with saline solution. Thanks for the answer.

I would really like to say a big thank you to the manufacturers of fluimucil-antibiotic, as this is the second time it has saved a child from bronchitis. There is no need to take a bunch of pills, we breathed through a nebulizer 2 times a day for 10 minutes, and on the third day my daughter stopped choking on coughing. Now if we have a lingering cough, we only breathe with it))))

Konstantin: What I liked about the drug Prostanorm: reasonable price, pronounced effect of taking it.

Valentina: I, too, am all about diet and exercise. I hoped for loads, I thought that my healthy lifestyle.

Nina: I was on pills for a year and a half, then somehow everything calmed down. Mostly climatefit.

Elena: With the onset of menopause, the skin completely deteriorated and became dry. I saw a cream for .

All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://medside.ru/fluimutsil-antibiotik-it

Fluimucil for inhalation is a new generation drug for the treatment of respiratory tract diseases

Diseases of the upper and lower respiratory tract are one of the most common reasons for visiting a primary care physician and pediatrician. This problem becomes especially relevant during the cold season, which in our climatic conditions lasts almost half of the year - from October to April. First-line drugs in most cases of wet cough are mucolytics. One of the most effective medications, also produced in an innovative dosage form, is Fluimucil for inhalation.

Before you continue reading: If you are looking for an effective method of getting rid of a runny nose, pharyngitis, tonsillitis, bronchitis or colds, then be sure to look at this section of the site after reading this article. This information has helped so many people, we hope it will help you too! So, now back to the article.

The modern pharmaceutical industry treats with particular trepidation the relatively new forms of expectorant drugs. As clinical trials have shown, proven by practice, the inhalation route of drug administration for diseases of the bronchi and lungs turned out to be almost the most effective. What is the secret of such drugs and how inhaled Fluimucil works, we will try to figure it out together.

Composition and features of the release form

The manufacturer of Fluimucil, the Italian pharmaceutical company Zambon, produces 14 different forms of the drug, and a special place among them is occupied by solution for injection and inhalation. It is used for nebulizer treatment. Fluimucil for inhalation is a solution containing 10% of the active substance - acetylcysteine. The volume of the solution is 3 ml.

In addition, there is another drug based on Fluimucil, Fluimucil-antibiotic IT. This remedy is a combination of acetylcysteine ​​and the broad-spectrum antibiotic thiamphenicol. Fluimucil antibiotic IT is available in the form of a powder with a dose of 500 mg, from which a solution for injection and/or inhalation is prepared. In the packaging of the drug, the dry powder ampoule also contains ampoules with a solvent - water for injection.

Features of pharmacological action

The effectiveness of Fluimucil's active ingredient, acetylcysteine, has been fully proven and is based on the chemical structure of the molecule. The sulfhydryl group contained in acetylcysteine ​​can “break” disulfide bonds that connect protein molecules (mucoproteins) present in mucus. This reduces the viscosity of sputum.

Another active substance that is part of Fluimucil-antibiotic-IT, thiamphenicol, is active against various bacteria, including pneumonia streptococci, staphylococci, Haemophilus influenzae, Klebsiella, Neisseria and other microorganisms. These bacteria are most often the causative agents of respiratory tract diseases.

The combination of thiamphenicol and acetylcysteine ​​is particularly stable: the mucolytic prevents the destruction of the unstable antibiotic. This ensures the long-term complex effect of the inhalation drug containing a complex of active ingredients - the antibiotic Fluimucil.

Advantages of the inhalation form of Fluimucil

Fluimucil for inhalation has undeniable advantages over oral, that is, internal dosage forms, and patient reviews confirm this. The smallest dispersed particles of the active substance, which are formed with the help of modern nebulizers, can penetrate into the lower parts of the respiratory tract.

Acetylcysteine ​​and thiamphenicol, which are delivered to the site of the inflammatory process, begin to act in the highest possible concentration. Indeed, in contrast to the inhalation route of administration, when administered orally, the bioavailability of the active substances is extremely low.

There is even such a thing as the “first pass” effect: acetylcysteine ​​entering the gastrointestinal tract is retained in the liver, as a result of which its bioavailability does not exceed 10%. This means that the vast majority of oral Fluimucil that enters the body does not enter the bloodstream and target organs - the bronchi and lungs.

In addition, inhaled solutions of Fluimucil and Fluimucil-antibiotic IT begin to work twenty times faster than internal ones. This quality is important, especially in situations that require immediate treatment. Sometimes, with severe pneumonia, acute bronchitis, and tuberculosis in the acute phase, immediate help is needed, which Fluimucil inhalations can provide.

Indications: what do the instructions for Fluimucil for inhalation say?

We have already mentioned that the diseases for which Fluimucil inhalation solutions are used include pathologies of the upper and lower respiratory tract. Let's try to list these diseases:

  • chronic pulmonary emphysema;
  • acute and chronic bronchitis;
  • chronic asthmatic bronchitis;
  • pulmonary tuberculosis;
  • bronchiectasis;
  • pneumonia;
  • pulmonary complications of cystic fibrosis;
  • primary pulmonary amyloidosis;
  • chronic obstructive pulmonary disease (COPD);
  • pulmonary fibrosis.

In addition, inhalations with Fluimucil are used during the rehabilitation treatment of postoperative patients, anesthesia, and post-traumatic conditions. The instructions for inhalation Fluimucil indicate that the drug is also used to prepare for some diagnostic tests.

Fluimucil antibiotic solution is also used for the treatment of otitis - both catarrhal and purulent - sinusitis, pharyngitis and laryngitis, but for this purpose the drug is used topically and not inhaled.

Side effects of inhaled Fluimucil

With the inhalation administration of Fluimucil, the likelihood of gastrointestinal side effects characteristic of acetylcysteine ​​preparations is practically eliminated. Adverse events that occur after inhalation with Fluimucil include:

  • reflex cough;
  • local irritation of the upper respiratory tract;
  • inflammation of the oral mucosa - stomatitis;
  • rhinitis (inflammation of the nasal mucosa);
  • drowsiness.

Particular attention should be paid to the potential for a rather serious adverse effect - bronchospasm. It can also occur with internal use of acetylcysteine, but inhalation administration significantly increases the risk of respiratory dysfunction.

Experimental evidence suggests that bronchospasm may occur almost unpredictably in some patients. If bronchospasm occurs, bronchodilators (for example, Salbutamol) are immediately prescribed. In patients prone to such adverse effects, the risk of respiratory impairment usually outweighs the benefit of inhaled Fluimucil. Therefore, in such cases, it is advisable to select an alternative mucolytic.

However, you should not be afraid ahead of time and wait with horror for an attack. Bronchospasm during the use of Fluimucil occurs quite rarely, even in patients with asthmatic bronchitis and bronchitis due to complications of bronchial asthma.

The combined inhaled antibiotic Fluimucil, in addition to the side effects characteristic of acetylcysteine, can additionally cause stomatitis, nausea and rhinitis.

When are inhalations with Fluimucil contraindicated?

Fluimucil is a fairly safe medicine. It is contraindicated only in case of individual sensitivity to the active substance, acetylcysteine, as well as thiamphenicol in the case of a combined drug. In addition, inhalations with Fluimucil should not be carried out during exacerbation of gastric and/or duodenal ulcers.

The combination of Fluimucil with thiamphenicol is also contraindicated in cases of changes in the blood picture: anemia, leukopenia and a decrease in the number of platelets.

Prescribing Fluimucil in any form, including inhalation, during pregnancy is associated with some risk, which is associated with the lack of studies of the drug’s effect in this category of patients. However, scientists have conducted a number of experiments studying the effects of acetylcysteine ​​on pregnant animals.

Thus, during studies on rabbits, pregnant females were administered 500 mg of the drug per kilogram of body weight per day. The result of the experiment proved the complete absence of a teratogenic effect.

However, despite encouraging animal experiments, doctors prefer not to prescribe acetylcysteine ​​preparations, including inhaled forms of Fluimucil, during pregnancy. The drug belongs to category B and is used in cases where the benefit to the woman outweighs the possible risk to the child. The same restriction has been established for acetylcysteine ​​in combination with thiamphenicol.

Studies of the effect of acetylcysteine ​​during breastfeeding have also not been conducted. Moreover, it is not known whether Fluimucil is absorbed into breast milk. Therefore, when treating nursing women, it is better to give preference to safer drugs with proven safety. But Fluimucil-antibiotic IT for inhalation is officially contraindicated during breastfeeding.

Effective Fluimucil: be careful!

Inhalations with Fluimucil are a very effective mucolytic agent. Already during the course of treatment, a fairly sharp increase in the volume of liquefied bronchial secretions may occur. The main sign of achieving a result is the appearance of a productive, perhaps quite frequent, cough reflex.

And then special care should be taken by parents of small children, as well as patients with a history of bronchospasm. After all, the risk of irritation of the respiratory tract and the appearance of breathing problems during treatment with Fluimucil increases. Make sure that the child coughs up sputum in time - this will prevent excessive accumulation of tracheobronchial secretions.

Inhalations with Fluimucil: how to treat correctly

For inhalation treatment of respiratory tract diseases, a 10% solution of Fluimucil is used, intended for both injection and inhalation administration.

The dosage of Fluimucil for inhalation is the same for both adults and children. The drug is taken in doses of 300 mg, which are contained in one ampoule of a 10% solution of Fluimucil. The medicine should not be dissolved in water or saline solutions; the form is already completely ready for use. The frequency of procedures is 1–2 times a day, the duration of treatment may vary depending on the severity of the disease. Inhalation should be carried out for 15–20 minutes.

The average course involves 5–10 days of inhalation therapy with Fluimucil. In the treatment of severe chronic pathologies of the bronchopulmonary system, the use of the drug for up to six months is quite acceptable.

Fluimucil antibiotic IT is also used for nebulizer therapy. However, unlike the form with acetylcysteine, this drug is available in powder form. How to prepare Fluimucil antibiotic for inhalation? Very simple. You need to open both ampoules - both with the powder and with the solvent - and mix them. The solvent can be introduced into the ampoule with the powder using a syringe, then shake well - and the drug is ready.

The dose of Fluimucil antibiotic for adults is 250 mg 1-2 times a day, and for children - 125 mg for each inhalation 1-2 times a day. The course of treatment should not last more than 10 days.

special instructions

Many drugs can interact with other medications, and acetylcysteine ​​is no exception. Therefore, before you start inhalations with Fluimucil, you should know that acetylcysteine ​​cannot be combined with antitussive drugs (for example, codeine-containing drugs, Sinecod, Libexin and others). Otherwise, there is a high probability of sputum stagnation due to suppression of the cough reflex.

And one more note concerns the combination of acetylcysteine ​​with an antibiotic. During treatment, especially in patients with changes in the blood picture, it is worth monitoring the level of leukocytes and granulocytes. If the number of white cells decreases by less than 4 thousand/μl and granular leukocytes by more than 40%, the drug is immediately discontinued.

Fluimucil inhalation during antibiotic treatment

If you are taking antibiotics simultaneously with inhalation or any other treatment with Fluimucil, it is important to take into account one more feature of the drug. The fact is that some antibacterial agents can react with acetylcysteine. As a result, the effectiveness of both the antibiotic and the mucolytic is greatly reduced. These antibacterial agents include:

  • antibiotics of the tetracycline group (except Doxycycline) - Tetracycline, Ofloxacin;
  • Ampicillin;
  • Amphotericin B.

If you are prescribed these medications, then at least two hours should pass between the time of taking them and inhalation with Fluimucil.

Inhalation Fluimucil: analogues

There are no substitutes for the IT antibiotic Fluimucil - the drug is original, and not a single manufacturer has yet released its generic version. There are few analogues of Fluimucil inhalation solution, but they exist. These include:

  • ACC injection, 10% solution for injection and inhalation from Hexal;
  • Mucomist, solution for inhalation 20% produced by the British corporation Bristol Myers.

Note that both Fluimucil and its substitutes belong to approximately the same price category, and the quality of all analogues fully complies with all European standards. Therefore, treatment with inhaled forms of both Fluimucil and its analogues is affordable, safe and very effective.

The article above and comments written by readers are for informational purposes only and do not encourage self-medication. Consult a specialist regarding your own symptoms and illnesses. When taking any medicine, you should always use the instructions that come with the medicine and your doctor's advice as a guide.

In order not to miss new publications on the site, it is possible to receive them by email. Subscribe.

Do you want to get rid of your nose, throat, lung and cold diseases? Then be sure to check it out here.

It is also worth paying attention to other drugs for bronchitis and cough:

Join, speak out and discuss. Your opinion may be very important to many readers!

Copying materials without written permission and an open link is prohibited.

Source: http://cc-t1.ru/preparaty/fluimucil_antibiotik_it.html

Instructions for use of fluimucil antibiotic it for inhalation + reviews

The drug Fluimucil antibiotic IT is considered one of the most effective antimicrobial drugs for the treatment of various respiratory infections. Most often it is prescribed for use in the form of inhalations, although the solution can also be used by injection. The medicine quickly eliminates unpleasant symptoms, and, for moderate diseases, one package is enough for a full three-day course of antibiotic therapy for a child or adult.

Fluimucil antibiotic IT for inhalation - instructions for use

From the name it becomes clear that this is not just a cough remedy, but a serious antimicrobial drug that can only be used as prescribed by a doctor. It has a number of contraindications and restrictions on use that must be taken into account to avoid complications or side effects. The following instructions for use for inhalation Fluimucil antibiotic IT will help you understand its composition, purpose and features of use, as well as assess all the risks of self-medication.

Composition of the drug

The medicine contains two main components that have a comprehensive effect on the cause and symptoms of the disease. The first of them, thiamphenicol, is one of the representatives of the group of amphenicol antibiotics that exhibit bacteriostatic activity against pathogenic microorganisms. The spectrum of antimicrobial action of Fluimucil antibiotic IT includes:

  • gram-positive pneumo- and streptococci, diphtheria bacillus, clostridia and listeria;
  • gram-negative Salmonella, Neisseria, Escherichia coli, Shigella, Yersinia, Brucella and Bacteroides.

The growth and reproduction of pathogenic microflora is stopped due to the suppression of protein synthesis in cells.

The second component - acetylcysteine ​​- is a mucolytic, that is, it thins sputum, thereby facilitating its discharge. It also enhances the therapeutic effect of the antibiotic, facilitating its penetration into the lung tissue, and prevents bacteria from attaching to the mucous membranes of the respiratory tract.

Release form

Fluimucil antibiotic IT is a product of the Italian pharmaceutical company ZAMBON SpA. It is produced in the form of a special substance (lyophilisate), from which a solution for injections, rinsing or inhalation is prepared by dilution. The active substances thiamphenicol and glycinate acetylcysteinate are contained in an amount of 810 mg for each of the three bottles in the package (500 of which are antibiotic). There are also 3 ampoules with 4 ml of solvent - water for injection. The lyophilisate also contains the auxiliary component disodium edetate.

Photo Fluimucil - IT antibiotic

Indications and contraindications for use

Fluimucil is an antibiotic in combination with a mucolytic, which has a pronounced therapeutic effect in case of damage to the respiratory system by strains of pathogenic bacteria that are sensitive to it. When administered by inhalation, thiamphenicol tends to accumulate in the respiratory tract, penetrating into tissues. The mucolytic is also quickly and evenly distributed. It is recommended to use the drug in the following cases:

  • ENT diseases (otitis and sinusitis), inflammation of bacterial origin in the upper parts of the respiratory system;
  • infections of the bronchial tree and lungs, which include chronic and acute forms of inflammatory processes in the bronchi, prolonged pneumonia, whooping cough, cystic fibrosis, lung abscess and empyema;
  • treatment and prevention of the consequences of various medical procedures in the respiratory tract (for example, tracheostomy, bronchoaspiration) and thoracic operations;
  • concomitant infections (including those caused by mycobacteria) in order to activate drainage.

Since the drug contains an antimicrobial component, it has some restrictions and prohibitions on use. Fluimucil antibiotic IT is contraindicated in the case of pathologies of the hematopoietic system, which are manifested by leuko- and thrombocytopenia, anemia. In addition, the medicine cannot be prescribed to patients with individual intolerance to any of the components of the drug.

During pregnancy, use is possible only if there is no effective alternative and the benefit to the woman predominates over possible teratogenic risks. Nursing women who are prescribed Fluimucil IT antibiotic should temporarily stop breastfeeding and regularly express milk (in order to maintain lactation).

A history of diseases such as renal and liver failure requires careful use of the drug. In addition, due to age-related characteristics of the excretory system, the use of the drug in children under 3 years of age is limited (strictly as prescribed by a doctor). It is not allowed to increase the dosage in the case of antibiotic therapy for persons over 65.

Dosages, treatment regimens and overdose

Fluimucil antibiotic IT in the form of inhalation is recommended to be used 1 or 2 times a day, after diluting the lyophilisate according to the instructions with the solvent included in the kit. The maximum duration of antibiotic therapy should not exceed 10 days. The daily dose is usually 500 mg of the active substance (1 bottle of ready-made solution) for adults and 250 mg for children, divided into 2 doses.

Fluimucil antibiotic is dripped into the nose or ear for diseases of the relevant organs (2-4 drops), used as intramuscular injections. In the latter case, adults are prescribed 500 mg twice or thrice a day, and for children the required amount of the drug is determined according to age. For example, premature infants and infants up to 2 weeks - 25 mg/kg per day, children under three years old - 125 mg twice a day, up to seven - 250 mg and over 7 - the same dose, but three times a day. In special cases (severe course of the disease), it is permissible to double the dosage in the first 3 days,

In a hospital setting, the solution is used to rinse cavities, introduce into the paranasal sinuses or endotracheally into the respiratory tract. This is done both for the purpose of treating bacterial infections and for prevention after surgical interventions and other medical procedures. The drug is diluted in the same way, used in an amount of 1 or 2 milliliters per administration.

If the recommended doses are exceeded, the composition of the bacterial microflora changes and signs of superinfection appear. The severity of side effects increases (with the exception of allergic manifestations). To combat the consequences of an overdose, maintenance drug therapy should be used.

Side effect

Inhalations using the drug Fluimucil antibiotic IT sometimes cause negative responses from the body. This may be allergies, nausea, reflex cough, runny nose, stomatitis, local irritation of the mucous membrane. In case of bronchospasm, special bronchodilator drugs should be used. Intramuscular injections are fraught with pain and a burning sensation at the injection site, as well as a change in the blood formula towards a decrease in such formed elements as red blood cells, platelets and leukocytes.

How to dilute the antibiotic Fluimucil IT for inhalation for children

It is quite easy to prepare the drug yourself. To do this, you need to open the bottle of powder and pour one of the included 4-ml ampoules of water for injection into it using a sterile syringe. The resulting solution contains 500 mg of antibiotic, which is the daily dose for an adult. It is used in 2 doses, and the remainder is stored in the refrigerator in a closed bottle until the next use.

For children, the recommended single dose of the drug Fluimucil antibiotic IT is half as much, therefore, after the described dilution of the lyophilisate with sterile water, proceed as follows:

  • draw a quarter of the volume of the prepared solution (1.25 ml) into a syringe (without a needle) from the bottle;
  • add 1 milliliter of pharmaceutical saline solution there;
  • Place the finished mixture in a compressor nebulizer.

The tightly sealed bottle of the prepared medicine should be stored in the refrigerator until the next use. The solution should not come into contact with metal or rubber surfaces.

special instructions

When using the drug Fluimucil antibiotic IT, you should take into account not only contraindications and restrictions, but also some other features. So, you should not allow it to come into prolonged contact with metal or rubber. In addition, during antibiotic therapy there is no need to use any antitussive systemic drugs or sprays. They lead to stagnation of sputum and slow down the healing process.

Reviews – Fluimucil antibiotic IT for inhalation

Patients' opinions about this drug are quite contradictory. Its only quality regarding which buyers are unanimous is its rather high cost (in pharmacies it is sold at a price of 650 rubles for one pack with three bottles). In addition, many note a specific bitter taste, which irritates the respiratory tract and can even cause nausea.

As for effectiveness, opinions are divided on this issue. About half of patients report excellent treatment results and rapid disappearance of symptoms. There are reviews that Fluimucil IT antibiotic helped get rid of severe forms of sinusitis, sinusitis and nasopharyngeal diseases. The rest express dissatisfaction with the lack of results, but, as a rule, there is no mention of any severe side effects.

Reviews of Fluimucil IT antibiotic for inhalation for children are in most cases positive. Many parents characterize it as a highly effective remedy for bronchitis, laryngotracheitis and rhinitis of bacterial origin. Since the medicine acts locally, there are practically no complaints about side effects.

This difference in the evaluation of the drug is presumably explained by the approach to the treatment of adults and children. Parents are more responsible, so they rarely show independence in such serious matters and follow the advice of a specialist. The pediatrician objectively assesses the need for the drug and prescribes the optimal dosage and course of antibiotic therapy.

Adults often self-medicate, without visiting a therapist, trying to cure a viral infection with an antibacterial agent, which in this case is completely ineffective. Thus, it is imperative to consult a doctor who will accurately determine the cause of the disease and recommend adequate drug therapy.

Trust your health to professionals! Make an appointment with the best doctor in your city right now!

A good doctor is a general specialist who, based on your symptoms, will make the correct diagnosis and prescribe effective treatment. On our portal you can choose a doctor from the best clinics in Moscow, St. Petersburg, Kazan and other Russian cities and receive a discount of up to 65% on your appointment.

* Clicking on the button will take you to a special page on the site with a search form and an appointment with a specialist of the profile you are interested in.

* Available cities: Moscow and region, St. Petersburg, Ekaterinburg, Novosibirsk, Kazan, Samara, Perm, Nizhny Novgorod, Ufa, Krasnodar, Rostov-on-Don, Chelyabinsk, Voronezh, Izhevsk

You may also like

You may also like

Vilprafen Solutab – instructions for use + analogues + reviews

Tsiprinol 500 – instructions + analogues + reviews of the drug

Pancef suspension – instructions for use + analogues and reviews

Add a comment Cancel reply

Popular articles

List of over-the-counter antibiotics + reasons for banning their free circulation

In the forties of the last century, humanity received powerful weapons against many deadly infections. Antibiotics were sold without prescriptions and allowed

Source:

Antibiotic fluimucil

Antibiotics are substances of plant, animal and microbial origin that can reduce the growth of microorganisms or cause their death. One of them is the antibiotic fluimucil - a drug that has an anti-inflammatory, mucolytic effect and has the ability to thin, facilitate and increase the volume of sputum production.

Fluimucil is used in the treatment of respiratory diseases that are accompanied by impaired sputum discharge, including chronic and acute bronchitis, tracheitis, bronchiolitis. It is also used for catarrhal and purulent otitis, sinusitis to improve the discharge of secretions. The antibiotic fluimucil is used in medicine for washing abscesses, maxillary sinuses, and nasal passages.

Fluimucil - release form

  1. Granules for making syrup.
  2. Effervescent tablets.
  3. Fluimucil powder for solution for injection.

In the case of acute and chronic rhinitis, as well as sinusitis, it is recommended to use the drug rinofluimucil for treatment - a convenient spray that evenly irrigates the nasal mucosa.

Instructions for use of antibiotic

Fluimucil in the form of granules should be dissolved in 1/3 glass of water before use. The required dose for the treatment of diseases in children over 6 years of age and adults is 200 mg 3 times a day. The dose for newborns is 10 mg/kg only in vital circumstances and under strict medical supervision. The daily dose for children from 1 year to 2 years is 200 mg in two divided doses per day, from 2 to 6 years 300 mg/day in three divided doses.

Fluimucil effervescent tablets - take 1 tablet once a day, dissolving it in 1/3 glass of water before use. These tablets are contraindicated in children under 18 years of age.

The injection solution is intended for parenteral, inhalation and endobronchial administration. The recommended dose for adults and children over 14 years of age is 300 mg 2 times a day, and for children aged 6 to 14 years - half the adult dose.

The duration of treatment depends on the characteristics of each disease and can range from 5 to 10 days, and in severe cases - several months.

When using the drug fluimucil orally, in rare cases, side effects from the digestive system may occur - diarrhea, nausea, vomiting, heartburn, stomatitis. With parenteral administration of an antibiotic, an allergic reaction on the skin may occur - rash, urticaria, or a slight burning sensation at the injection site.

When using the drug inhaled, reflex cough, rhinitis, stomatitis or local irritation of the respiratory tract may occur.

The antibiotic fluimucil is contraindicated for use in patients during an exacerbation of disease of the stomach and duodenum, as well as in cases of individual hypersensitivity to any of its components. This drug should be taken with caution in case of liver disease, kidney disease, bronchial asthma, adrenal dysfunction and pulmonary bleeding.

Today, among the well-known drugs, there are several analogues of the antibiotic fluimucil:

In modern life, when selecting treatment, doctors, guided by the basics of evidence-based medicine, reduce the likelihood of ineffective use of drugs. The antibiotic fluimucil is a modern medicine that has repeatedly proven its effectiveness in the treatment of cough, pneumonia, bronchitis and a number of other diseases.

Copying information is permitted only with a direct and indexed link to the source

Source: http://womanadvice.ru/antibiotik-fluimucil

What kind of drug is Fluimucil Antibiotic and features of its use

Fluimucil Antibiotic belongs to the combination of therapeutic agents and has recently been increasingly used to treat bacterial infections of the respiratory tract of a child. It consists of a complex of two active substances - the antibiotic thiamphenicol and the mucolytic acetylcysteine. This allows not only to suppress microorganisms that caused the development of inflammation, but also to significantly alleviate the patient’s symptoms. There are no analogues to Fluimucil Antibiotic yet.

Pharmacological features

Acetylcysteine ​​belongs to the group of mucolytic drugs. It is able to break disulfide bonds between mucopolysaccharides of sputum, which leads to a decrease in viscosity and an increase in mucus volume.

Acetylcysteine ​​also stimulates the secretion of mucous cells of the mucous membrane of the respiratory tract and suppresses the formation of free radicals.

As a result, damage to healthy cells decreases and the severity of the inflammatory process decreases. The maximum concentration is reached 3 hours after taking acetylcysteine. The drug is excreted from the patient's body in the form of inactive metabolites in the urine.

Thiamphenicol is a synthetic antibiotic from the amphenicol group. The mechanism of action is associated with disruption of protein synthesis in the cells of pathogenic bacteria.

It has a bacteriostatic effect on the following microorganisms, which are the most common pathogens of respiratory tract infections in humans:

  • hemophilus influenzae;
  • Klebsiella;
  • Neisseria;
  • corynebacterium;
  • streptococcus;
  • staphylococcus;
  • some anaerobic bacteria.

After application, thiamphenicol quickly reaches the required therapeutic concentration in the mucous membrane. Only a small part of the drug binds to blood proteins. Thiamphenicol undergoes a transformation process in the liver, after which it loses its activity. It is excreted from the patient's body by the kidneys, as well as with bile and feces.

The combined use of these substances allows you to accumulate their positive effects.

Acetylcysteine ​​inhibits the ability of pathogenic microorganisms to adhere and colonize mucous membranes. It also frees up access for antibiotics to hard-to-reach areas. Thus, when used topically, thiamphenicol exhibits its bacteriostatic effect more effectively, which leads to a faster recovery of the patient.

Indications for use

According to the instructions for use, Fluimucil Antibiotic is used for the treatment and prevention of bacterial infections of the human respiratory system. The drug is used for the following conditions:

  • development of acute and chronic bronchitis (including recurrent);
  • bacterial pneumonia;
  • infection associated with cystic fibrosis;
  • lung abscess;
  • complicated emphysema;
  • bronchiectasis (in the acute stage);
  • bronchiolitis;
  • sinusitis;
  • purulent and catarrhal otitis media;
  • pharyngitis;
  • laryngitis;
  • prevention of postoperative complications from the respiratory system in high-risk patients;
  • preparation for manipulations (bronchography, bronchoscopy, aspiration drainage);
  • the need to improve drainage in case of nonspecific infection;
  • treatment of bacterial respiratory tract infections after surgery.

Release form Fluimucil Antibiotic

The drug is produced by the Italian pharmaceutical company Zambon. One package contains 3 bottles of thiamphenicol glycinate acetylcysteinate (500 mg) and 3 bottles of injection solution.

Contraindications of the drug

Fluimucil Antibiotic should not be prescribed to patients with the following conditions:

  • hypersensitivity to the components of the drug;
  • impaired renal function (reduced glomerular filtration);
  • chronic or acute liver pathology;
  • presence of lactation;
  • taking drugs that inhibit hematopoiesis;
  • anemia;
  • leukopenia;
  • thrombocytopenia.

During pregnancy, the drug can be used only in cases where alternative drugs are less safe. Also, Fluimucil Antibiotic should not be prescribed to children under 2 years of age, since their renal function is not sufficiently developed.

Side effects of Fluimucil Antibiotic

Among the side effects that occur when using Fluimucil Antibiotic, the most common are allergic reactions if the patient is intolerant to the drug. They can be different: from redness of individual areas of the skin and/or mucous membranes to anaphylactic shock. Fortunately, they are observed in a small number of patients.

Also, Fluimucil Antibiotic can accumulate in the body when kidney function is impaired and inhibit the process of hematopoiesis in the bone marrow. In the laboratory, this is manifested by a decrease in the number of red blood cells, leukocytes, reticulocytes and platelets in a general blood test.

Clinically, it is possible to identify signs of anemia, the addition of a secondary bacterial infection, generalization of the inflammatory process and the appearance of hemorrhages in the skin and mucous membranes.

When inhaling the drug, some patients experience irritation of the mucous membranes of the oropharynx, feelings of general weakness and nausea. Stomatitis and rhinitis may develop.

Method of use of the drug

The drug can be used intramuscularly, intravenously, locally and for inhalation.

The dose for parenteral administration of Fluimucil Antibiotic in adults is 0.5 g 2 or 3 times a day. Before this, be sure to dissolve the contents of the bottle in 3-4 ml of solution for injection. Children should be prescribed this drug, taking into account their age and body weight: up to 3 years - 25 mg per 1 kg in the morning and evening, from 3 to 7 years - 250 mg 2 times a day, over 7 years - 250 mg 3 times a day .

In some cases, if the disease is severe, the dosage of Fluimucil Antibiotic can be doubled in the first two to three days. But this should not be done for children, elderly patients and pregnant women. The course of therapy usually lasts 5-7 days, but in some cases the doctor can extend it to 10 days. Resistance to therapy usually develops slowly.

Fluimucil Antibiotic for inhalation is used as follows. 4 ml of solution for injection from the ampoule is also injected into the bottle with the lyophilisate. But for inhalation, adults need only 250 mg (2 ml), and children – 125 mg (1 ml) of the drug. Therefore, it is important to carefully measure the required amount of Fluimucil Antibiotic using a syringe. The remainder in the bottle can be left for the next use. The prepared solution for inhalation should be stored in the refrigerator for no more than 24 hours.

For otitis media, after preparation, the drug can be instilled 1-2 drops into the sore ear 3 times a day. Fluimucil Antibiotic is also used for endotracheobracheal lavage, 1-2 ml, depending on need.

Some reception features

It is necessary to take Fluimucil Antibiotic only after an appropriate prescription from a doctor. Self-medication (including using the drug for inhalation) can lead to complications and side effects.

With long-term use of Fluimucil Antibiotic (more than 10 days), you need to regularly conduct a general blood test and biochemical study of creatinine and urea levels. At the first signs of suppression of hematopoiesis or decreased renal function, you should immediately stop taking the drug.

At the beginning of therapy with Fluimucil Antibiotic, especially in patients after surgical operations on the respiratory system, the amount of sputum increases, which the patient cannot cough up on his own. Therefore, postural drainage and bronchoaspiration should be considered in such cases. In bronchial asthma, inhalation of the drug sometimes leads to the development of bronchospasm.

Interaction with other drugs

Since Fluimucil Antibiotic contains acetylcysteine, it is strictly prohibited to use it together with any antitussive drugs.

This leads to stagnation of sputum in the bronchial system, which can cause the progression of the primary disease and the development of complications.

Also, Fluimucil Antibiotic should not be used with bactericidal antibiotics (penicillins, cephalosporins, carbapenems). This is explained by the fact that their combination with thiamphenicol leads to a mutual decrease in effectiveness.

Is Biseptol an antibiotic? . What kind of drug is Fluimucil Antibiotic and features of its use.

What kind of drug is Fluimucil Antibiotic and features of its use. . Analogues of the drug Hemomycin - a brief overview of drugs.

What kind of drug is Fluimucil Antibiotic and features of its use. Analogues of the antibiotic Sumamed - review of properties.

What drugs are broad-spectrum antibiotics? What kind of drug is Fluimucil Antibiotic and features of its use.

What kind of drug is Fluimucil Antibiotic and features of its use. What is better and in what case - Augmentin or Sumamed.

Similar articles

Fusiderm B - instructions for use

Using Tobrex for children - are there any contraindications?

Areas of application and properties of alcohol solution of chloramphenicol

Leave a comment Cancel reply

Similar articles

Is Biseptol an antibiotic? . What kind of drug is Fluimucil Antibiotic and features of its use.

What kind of drug is Fluimucil Antibiotic and features of its use. . Analogues of the drug Hemomycin - a brief overview of drugs.

Source: http://med-antibiotiki.ru/instrukcii/chto-za-preparat-fluimucil-antibiotik-i-osobennosti-ego-primeneniya/