Fluimucil antibiotic for inhalation for children

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Fluimucil - IT antibiotic

Description current as of 05/16/2014

  • Latin name: Fluimucil – antibiotic IT
  • ATX code: J01BA02
  • Active ingredient: Thiamphenicol glycinas acetylcysteinas (Thiamphenicol glycinas acetylcysteinas)
  • Manufacturer: Zambon, Italy

Compound

One bottle contains: glycinate acetylcysteinate thiamphenicol – 0.81 g, including thiamphenicol 500 mg; additional substance – disodium edetate; water as a solvent.

Table of contents:

Release form

Powder obtained by lyophilization, from which a solution is prepared; in bottles complete with solvent, 3 pcs. in a pack.

pharmachologic effect

The substance is a combination of an antibiotic and a mucolytic drug.

Thiamphenicol has a wide spectrum of action on bacteria that cause respiratory tract infections - both gram-positive (streptococci, clostridia, staphylococci) and gram-negative (neisseria, Haemophilus influenzae, salmonella, yersinia, E. coli).

Acetylcysteine ​​actively dilutes sputum and purulent discharge, promotes sputum discharge, reducing viscosity.

Acetylcysteine ​​promotes better penetration of thiamphenicol into the lung tissue and prevents the adhesion of microorganisms to the mucous membrane of the respiratory system.

Pharmacodynamics and pharmacokinetics

Thiamphenicol accumulates in the respiratory tract, and maximum concentration occurs within 1 hour after injection into the muscle. The half-life is 3 hours, excreted in the urine.

Acetylcysteine ​​accumulates in the intercellular space, bronchial secretions, lung tissue, liver and kidneys. Half-life – 2 hours; excreted by the kidneys, and a small part through the intestines.

The drug penetrates the placenta.

Indications for use

  • damage to the ENT organs and upper respiratory tract (sinusitis, otitis, laryngotracheitis);
  • diseases of the lower respiratory system (bronchitis, lung abscess, pneumonia, bronchiectasis, cystic fibrosis, emphysema, whooping cough, bronchiolitis);
  • treatment and prevention of infectious and obstructive complications after tracheostomy, thoracic surgery (atelectasis, bronchopneumonia);
  • preparation for aspiration of bronchial secretions and bronchoscopy;
  • in order to improve drainage in case of concomitant pulmonary infections (including tuberculosis, the presence of cavernous lesions).

Contraindications

  • diseases and changes in blood count (leukopenia, anemia, thrombocytopenia);
  • individual intolerance to substances included in the drug.

Kidney function in children of the first 2 years of life has features associated with age, therefore, in them, as well as in patients with severe damage to the liver and kidney functions, the drug must be used with caution.

Side effects

Allergic reactions.

When injected into a muscle, there may be a burning sensation at the injection site; rarely leukopenia, thrombocytopenia, anemia, neutropenia, reticulocytopenia.

Using the antibiotic Fluimucil for inhalation can cause irritation of the respiratory mucosa, reflex cough, nausea, and rhinitis. Sometimes bronchospasm occurs, and bronchodilators should be used.

Instructions for use Fluimucil - IT antibiotic (Method and dosage)

Use intramuscularly in the dose:

  • for adults, it is administered daily in 3 doses;
  • children under three years of age 125 mg twice daily;
  • children from 3 to 7 years mg twice a day;
  • for children: 750 mg per day, divided into 3 injections.

For newborns up to 2 weeks, as well as premature infants, use a dose of 25 mg/kg body weight per day.

How to dilute for inhalation?

For adults, 500 mg of dry substance is dissolved in 4 ml of water for injection and divided into 2 doses per day (2 ml each). Inhalations for children are prepared in the same amount of water for injection as for adults (4 ml), dissolving 250 mg of powder and also used twice a day.

Locally for washing the paranasal sinuses, incl. after surgical interventions, for endotracheal administration through a tracheostomy, bronchoscope or endotracheal tube, the powder is dissolved using water for injection in an amount of 4 ml, 500 mg for adults and 250 mg for children.

For otitis and diseases of the nasopharynx, 2-4 drops are instilled into the nasal passage or ear canal.

In case of appropriate indications, the dose of the drug can be doubled.

In newborns, premature and elderly patients, do not increase the dose.

The instructions for the antibiotic determine the course of treatment with the drug for no more than 10 days.

Overdose

Possible increased side effects of the drug, superinfection, disturbances of the bacterial flora. Symptomatic therapy is used as treatment.

Interaction

If you use cough suppressants, mucus stagnation may occur.

It is not recommended to mix the inhalation antibiotic Fluimucil with other substances in an aerosol.

Terms of sale

Storage conditions

Away from children and at temperatures between 15 and 25°C.

Best before date

special instructions

During the treatment period, constant monitoring of the blood count is necessary. If the number of granulocytes and leukocytes decreases, the drug should be discontinued.

Avoid contact of the solution with rubber and metal surfaces.

Analogs

It has no analogues.

For children

Use with great caution in children under two years of age, due to age-related characteristics of kidney function.

During pregnancy and lactation

Prescribe only when the benefit to the woman outweighs the risk to the fetus. During breastfeeding, if treatment is necessary, feeding should be stopped.

Reviews about Fluimucil – IT antibiotic

On many medical forums, there are reviews about Fluimucil, an antibiotic, usually from young mothers who used this antibiotic for inhalation for children. They note a quick effect - literally within 3-4 days the child’s condition improves. Those who have tried the drug at least once prefer it when they get sick again. It is very good to use the drug for a nebulizer - both convenient and effective.

Price Fluimucil – IT antibiotic, where to buy

In Russia, the price of Fluimucil-antibiotic IT ranges from 413 to 605 rubles.

The average price of Fluimucil for inhalation in Moscow is about 538 rubles. In Ukraine, the drug can be purchased for 174 UAH.

Hello! The doctor prescribed the child inhalations with the antibiotic fluimucil, but did not describe in what proportions. Do I need to add saline and if so, how much? The child is almost 3 years old. Cough and sore nasopharynx. Thank you in advance.

Fluimucil is an antibiotic. It greatly irritates the respiratory tract. My throat breaks after it. My throat hurts and stings from it. And my nose too. I don’t know if I still need it. For now I try it once a day. I seem to have bronchitis in the acute phase. Sputum. green. .but now it’s not like that anymore. A little lighter.

715 RUR bought on March 30, 2016 in a pharmacy next to Alpha Bank on the lands of Lipetsk

She was treating bronchitis (against the background of bronchial asthma). On the second day, a good effect from the inhalations was already noticeable. Great: fast, high quality, affordable.

My son is three years old, and his ENT doctor prescribed inhalations as follows: we dilute one injection bottle of water with 500 mg of powder. Then pour 3 ml of saline solution and 1 ml of the resulting solution into the inhaler. We inhale for 10 minutes, twice a day. One diluted ampoule is enough for 2 days. Store in the refrigerator. We are treated for six days. Snot and cough go away.

There is 500 mg of powder in a bottle, 4 ml of water in an ampoule - this is a dose for an adult for 2 doses. I have a question. Is it possible to dilute 500 mg in 8 ml of water and use it in 4 doses for a child? If possible, where and for how long should the solution be stored? In a refrigerator? And how to avoid contact of the solution with metal and rubber if you draw the solution with a syringe with a NEEDLE and the stopper of the bottle is RUBBER. Thank you.

I have asthma, COPD, emphysema. The doctor prescribed Fluimucil antibiotic inhalation through a nebulizer. During inhalation, severe suffocation occurred. Should I continue doing inhalations?

please tell me, my husband has sinusitis, but it bothers him when he is sick, but otherwise, can fluimucil-antibiotic IT help? Thanks in advance)

The drug helped us. We did inhalations for 5 days.

Alice, please tell me how old your child is, and in what proportion the antibiotic fluimucil should be diluted for inhalation. We were also prescribed it, our daughter has obstructive bronchitis, but I didn’t understand how to dilute it, with the water in the box or with saline solution. Thanks for the answer.

I would really like to say a big thank you to the manufacturers of fluimucil-antibiotic, as this is the second time it has saved a child from bronchitis. There is no need to take a bunch of pills, we breathed through a nebulizer 2 times a day for 10 minutes, and on the third day my daughter stopped choking on coughing. Now if we have a lingering cough, we only breathe with it))))

Konstantin: What I liked about the drug Prostanorm: reasonable price, pronounced effect of taking it.

Valentina: I, too, am all about diet and exercise. I hoped for loads, I thought that my healthy lifestyle.

Nina: I was on pills for a year and a half, then somehow everything calmed down. Mostly climatefit.

Elena: With the onset of menopause, the skin completely deteriorated and became dry. I saw a cream for .

All materials presented on the site are for reference and informational purposes only and cannot be considered a treatment method prescribed by a doctor or sufficient advice.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://medside.ru/fluimutsil-antibiotik-it

Fluimucil antibiotic for inhalation for children

Fluimucil for inhalation

For inflammatory diseases of the upper respiratory tract, medications (antibiotics, antiviral and antitussive agents), general procedures that activate the immune system, and local procedures are used. One of the effective methods of treating children and adults is inhalation. In this case, you need to strive to ensure that the active substance in the solution penetrates as deeply as possible into the trachea and bronchi.

Modern ultrasonic inhalers make it possible to achieve atomization of the drug to the smallest particles, which ensures a good therapeutic effect.

Advantages of Fluimucil solution for inhalation

Fluimucil is a synthetic drug produced by the Italian company Zambon Group. The active chemical is acetylcysteine.

Acetylcysteine ​​has several types of effects on the upper respiratory tract:

  • thins thick mucous and mucopurulent sputum in the paranasal sinuses, on the surface of the trachea and bronchi;
  • increases mucus production;
  • has a local anti-inflammatory effect due to the activation of immune cells;
  • ensures cleansing of the bronchi and paranasal cavities;
  • is not an antibiotic, but in the combined composition the solution of Fluimucil-antibiotic IT additionally has an antimicrobial effect.

Fluimucil and Fluimucil-antibiotic IT are available in a convenient form:

Fluimucil in ampoules of 3 ml of 10% solution for inhalation. each contains 300 mg of acetylcysteine.

Fluimucil-antibiotic IT in the form of lyophilisate, 250 and 500 ml in bottles. To dissolve it, the packaging contains ampoules with sterile water.

The instructions for using the solution suggest diluting the opened ampoule in half with boiled water or sterile saline solution and using it within two days. The solution must be prepared only in glass containers and avoid contact with metal or rubber. These substances inactivate acetylcysteine.

To prepare a solution for one procedure, add 2 ml of sterile water from a 250 ml ampoule to the lyophilisate.

The characteristic smell of sulfur compounds is always present when the ampoule is opened.

Indications

Inhalation of Fluimucil is best done using simple home inhalers or the most modern ultrasonic nebulizer. The use of a specially selected mask allows children to be treated with inhalations. Contraindicated for use in children under two years of age. The nebulizer is considered the most effective in its method of penetration into the upper and lower respiratory tract. Therapeutic home procedures are indicated for coughs in children and adults accompanying

  • acute and chronic bronchitis,
  • laryngitis,
  • rhinitis,
  • inflammation of the paranasal sinuses,
  • tracheitis.

Cough caused by an acute respiratory viral infection can be effectively treated with inhalation of Fluimucil solution.

Dosage of the drug

Fluimucil for inhalation is prescribed to children from two to six years old, 1 ml twice a day, over six - 2 ml twice a day. Children over 12 years of age and adults can use 3 ml of solution twice a day. The duration of treatment is determined by the doctor. Usually the course does not exceed ten days.

Compatibility with other tools

The use of Fluimucil inhalations is not recommended to be combined with internal or intramuscular treatment with antibiotics such as tetracycline, amphotericin B, ampicillin. These drugs reduce each other's effectiveness.

Antitussives that act on the cough reflex, on the contrary, intensify, and sputum stagnation occurs. This option can contribute to the occurrence of pneumonia in weakened patients and children.

During inhalation, part of the acetylcysteine ​​is absorbed into the bloodstream. If a person takes nitrates such as nitroglycerin and other drugs to treat coronary heart disease, their effect is enhanced.

Restrictions and contraindications for children and adults

Recommendations for the use of Fluimucil inhalations are limited if there is a tendency to pulmonary bleeding (hemoptysis), bronchial asthma or spastic bronchitis.

Children may experience nausea due to the specific smell of the drug. Rarely, there is a runny nose, bronchospasm (attacks of suffocation), and stomatitis.

Absolute contraindications to the use of drugs are:

  • blood diseases;
  • increased allergic sensitivity;
  • pregnancy and lactation;
  • age up to two years.

Just as for internal use, restrictions, according to the instructions, apply to chronic diseases of the digestive organs, liver, and kidneys.

All questions regarding treatment with Fluimucil should be discussed with your doctor.

Review: The drug Fluimucil - Excellent effect when used in the form of inhalations

Attention! Before using medications, consult a specialist!

helped very quickly

like any antibiotic, but did not manifest itself in our case

Fluimucil®-antibiotic IT is a combination drug; it combines an antimicrobial agent and a mucolytic that dilutes sputum.

What I like most about it is that it can be used as an inhalation, so it becomes a topical antibiotic, so it doesn't have many side effects. The solution can also be used for injection.

We used it for a child (3.5 years old). My daughter had a terrible cough, wet and practically unproductive; 3-day inhalations with Lazolvan did not help. Moreover, the cough was very intrusive, the child was exhausted.

The doctor prescribed this drug to us. By the way, I hope you will not self-medicate; only a doctor should prescribe such medications.

There was no wheezing in the lungs, just heavy breathing. The diagnosis is acute pharyngitis. The temperature lasted 3 days and reached 38.5.

We took the first inhalation in the evening, and the next day the cough ceased to be obsessive, a significant relief.

After another day of use, the cough became more productive and stopped during sleep. Plus the temperature dropped to 37.

It was nice that the effect was achieved only when applied locally.

The package with the drug contains 3 bottles of powder and 3 ampoules of water for injection. There is actually one bottle missing from the photo, it has already been used.

For inhalation, we were prescribed to dilute 1 bottle of powder with 8 ml of saline solution.

Dosage for children: 125 mg per inhalation 1-2 times a day. We were prescribed 2 times.

It turned out that one bottle of medicine is enough for 4 applications (for one inhalation you need to take 2 ml of the diluted drug). Store the opened bottle with the finished medicine in the refrigerator (nothing happens to it in 2 days).

Duration of use is 3-5 days depending on symptoms. Everything went through for us in 4 days.

The drug is not cheap, after the course there was only one bottle of powder and 3 unusable water for injections left.

In general, the experience of using it is positive for us. If the doctor ever prescribes it again, we will be treated.

Health to you and your children!

Time of use: 1 course

General impression. Excellent effect when used in the form of inhalations

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Published in the magazine:

DISTRICT PEDIATRIST; No. 4; 2013.

Use of the drug Fluimucil - Antibiotic IT in inhalation therapy of respiratory infections

When using an inhaler, medicinal substances act much more effectively on the target organ due to the rapid penetration of the medicinal substance. Due to the local effect, this method is gentle and safe, which is especially important in pediatrics.

Nebulizer therapy can be easily used both in the hospital and at home.

In the treatment of rhinosinusitis, it is especially important to penetrate the drug to the source of inflammation - the paranasal sinuses. Maximum impact is possible only in the case of nebulizer therapy, since conventional “home” inhalations and various nasal sprays are not able to penetrate the sinuses.

Antibacterial therapy: systemic and local drugs

Fluimucil, an IT antibiotic, is the only drug that combines the direct mucolytic N-acetylcysteine ​​and the broad-spectrum antibiotic thiamphenicol. Its use allows you to solve two problems simultaneously - influencing pathogenic microflora and removing thick secretions in the nasal cavity and sinuses.

For patients with chronic and recurrent diseases, it is advisable to have a personal nebulizer

There are several general rules for using medications for nebulizer therapy:

The volume of liquid recommended for nebulization in most nebulizers is 3-4 ml (minimum 2 ml). If necessary, to achieve this, saline solution must be added to the drug.

With the help of nebulizers, you can use a wide range of drugs (all standard solutions for inhalation can be used) and their combinations (the possibility of simultaneous use of two or more drugs).

It is not recommended to use for nebulizers all solutions containing oils, suspensions and solutions containing suspended particles, including decoctions and infusions of herbs, solutions of theophylline, papaverine, platiphylline, diphenhydramine and similar products, as they do not have points of application on the mucous membrane of the respiratory tract *.

*Russian national program “BA in children. Treatment strategy and prevention", 2012.

Advantages of inhaled use of Fluimucil, an IT antibiotic:

When taking some antibiotics and direct mucolytics, it is necessary to observe a time interval of at least 2 hours.

Fluimucil, an IT antibiotic, is a ready-made dosage form that allows you to use these drugs simultaneously.

Local use of Fluimucil, an IT antibiotic, allows you to quickly achieve the maximum concentration of the drug directly at the site of inflammation.

Due to its local effect, Fluimucil, an IT antibiotic, has a high safety profile and has no systemic adverse reactions.

The combination of a mucolytic and an antibiotic in one drug eliminates the need for additional medications, which ensures high compliance with therapy.

Rhinosinusitis is one of the important indications for nebulizer therapy. This is not only safe, but also a highly effective method of treating acute and recurrent rhinosinusitis*. Using a nebulizer can reduce the need for systemic antibiotics or avoid them altogether. Due to the local action, the safety of inhalation therapy is significantly higher than taking systemic drugs.

* E.P. Karpova, D.A. Tulupov. On the possibilities of nebulizer therapy in the treatment of acute rhinosinusitis in children. Russian otorhinolaryngology. No. 4, 2013.

Using the drug Fluimucil - an IT antibiotic using a nebulizer

  • The maximum effect of the drug is achieved when it is injected directly into the site of inflammation. With the help of inhalation therapy for rhinosinusitis, the drug enters directly into the paranasal sinuses and acts on their thick contents.
  • Fluimucil is an IT antibiotic that should be used using a compressor nebulizer.

    Ultrasonic nebulizers are not suitable for the use of Fluimucil, an IT antibiotic. They are capable of destroying the active components of the drug.

    Fluimucil - IT antibiotic

    Indications for use and dosage

  • Fluimucil is an IT antibiotic used to treat infectious and inflammatory diseases caused by microorganisms sensitive to the drug and accompanied by mucostasis.
  • Diseases of the upper respiratory tract and ENT organs: exudative otitis media, sinusitis, laryngotracheitis.
  • Diseases of the lower respiratory tract: acute and chronic bronchitis, prolonged pneumonia, lung abscess, emphysema, bronchiectasis, cystic fibrosis, bronchiolitis, whooping cough.

    At a dosage of 125 mg, it is necessary to additionally add 1-2 ml of saline solution to the drug in the nebulizer.

    Source: http://orebenkah.ru/ingaljacii-dlja-detej/fluimucil-antibiotik-dlja-ingaljacij-detjam.html

    Mom is a doctor. For any child, the best doctor is the mother.

    A site for loving mothers.

    Fluimucil antibiotic for a child

    Sometimes, with a cough and runny nose, you can’t do without an antibiotic. Parents don’t really want to give their child an antibiotic by mouth, much less give injections. Today, a good alternative has appeared - fluimucil antibiotic for children - an antibiotic for inhalation, and even in combination with a mucolytic.

    Fluimucil antibiotic composition

    The medicine consists of the antibiotic thiamphenicol and the mucolytic acetylcysteine. Thiamphenicol and acetylcysteine ​​in this medicine are bound together into one molecule. This substance can be introduced into the body by aerosol or inhalation. The connection with acetylcysteine ​​stabilizes the drug, allowing it to be stored longer without deteriorating.

    To date, fluimucil antibiotic is the only antibiotic that can be administered into the body in this way. And this is not a topical drug. It penetrates well into the blood, providing a pronounced systemic antibacterial effect. But a particularly high concentration of it is created at the site of its administration - in the respiratory tract and mucus, which is very beneficial when the medicine is used to treat respiratory diseases.

    In the respiratory tract, the drug is broken down into thiamphenicol (its own antibiotic) and acetylcysteine ​​(mucolytic). Acetylcysteine ​​improves the transport of the antibiotic to the lower respiratory tract and to microbes located in lumps of mucus inside the bronchi. Thus, the effect of the antibiotic is enhanced.

    Antibiotic

    Thiamphenicol is a broad-spectrum antibiotic.

    Its predecessor is chloramphenicol (chloramphenicol). According to the spectrum of action, thiamphenicol is close to chloramphenicol, but lacks its side effects (hepatotoxicity, inhibition of hematopoiesis, etc.)

    Thiamphenicol is effective against the main bacterial pathogens of respiratory diseases in children: pneumococcus, streptococcus, Haemophilus influenzae, some strains of Staphylococcus aureus, Legionella, chlamydia, mycoplasma.

    Thiamphenicol with this method of administration has less effect than other antibiotics on the intestinal microflora and does not irritate the stomach and intestines at all.

    Mucolytic

    Acetylcysteine ​​remarkably thins mucus and helps its removal, improves the penetration of the antibiotic into the mucus and into the small bronchi and alveoli. But mothers must remember that when using acetylcysteine, in order for the medicine to be effective, the child needs to drink plenty of fluids.

    When is fluimucil antibiotic suitable for a child?

    The pediatrician must prescribe the antibiotic Fluimucil to the child.

    The drug can be used for rhinosinusitis, prolonged bacterial rhinitis, laryngotracheitis, tracheitis, bronchitis, bronchiolitis, cystic fibrosis, pneumonia.

    When treating with this medicine, additional expectorant, antitussive, and mucolytic medications are not required.

    Other antibiotics are also not prescribed with this drug.

    This may reduce the effectiveness of the drug.

    Fluimucil antibiotic for a child How to do inhalation?

    For inhalation of fluimucil antibiotic, only a compressor nebulizer is suitable, since the drug is destroyed in an ultrasonic nebulizer.

    Different nebulizer particle sizes are needed to treat different diseases. It is very good if the nebulizer can be set to a given particle size.

    • If fluimucil antibiotic is used to treat rhinosinusitis, rhinitis, the particle size should be greater than 10 microns.
    • If you plan to treat laryngitis or tracheitis, you need a particle size of 5-10 microns.
    • If bronchitis is being treated - 2-5 microns.
    • Particles of 0.5-2 microns are suitable for the treatment of pneumonia.

    If you are treating rhinitis or rhinosinusitis, it is better to breathe through a mask through your nose.

    If laryngitis, tracheitis, bronchitis, pneumonia are being treated, it is better to breathe through the mouthpiece with your mouth.

    Fluimucil antibiotic is sold in pharmacies in the form of a dry powder in bottles containing 500 mg of the main active ingredient. Each bottle comes with a 4 ml ampoule of water for injection. Before inhalation, water for injection is added to the bottle with the drug using a syringe.

    After dissolving the powder, a solution with a volume of approximately 5 ml is obtained. The prepared solution can be stored in the refrigerator in a closed sterile bottle for 24 hours.

    The therapeutic dose of the drug for children from birth to 12 years is 125 mg per inhalation 1-2 times a day. (In children under 2 years of age, the medicine is used with caution).

    To receive this dose of the drug, you need to draw 1.25 ml of the resulting fluimucil solution from the bottle with a syringe and add 1 ml of physiological solution to it.

    The solution for one inhalation is ready.

    • Duration of inhalation is 5-7 minutes.
    • The duration of treatment is 8-10 days.

    Fluimucil

    There is also a drug called fluimucil - acetylcytein - a mucolytic, without an antibiotic. An effective mucus thinner. Taken orally. There is no drug for inhalation use, fluimucil, without an antibiotic additive.

    This is all about fluimucil antibiotic for a child. Stay healthy!

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    Source: http://mamadoktor.ru/38-284/fluimutsil-antibiotik-rebenku.html

    How to use the antibiotic Fluimucil for inhalation for children and adults?

    Fluimucil antibiotic for inhalation is widely used in the treatment of most infectious and inflammatory diseases of the respiratory tract. The popularity of the drug is due to the fact that the inhalation method of treatment is much more effective than taking medications in tablets. During the procedure, the solution is sprayed, the smallest particles of active substances penetrate directly into the bronchi and trachea, providing the necessary therapeutic effect.

    Fluimucil for inhalation - description, properties

    Fluimucil is a drug from the group of mucolytics that provides liquefaction and removal of thick sputum. The active ingredient, acetylcysteine, is capable of breaking the disulfide bonds of mucopolysaccharides in sputum (including purulent). As a result, the viscosity of mucous secretions decreases, and they leave the respiratory tract faster.

    The manufacturer of the medicine, the Swiss company Zambon, produces this medicine in different forms - effervescent tablets, solution for injection, granules for preparing a suspension, lyophilisate for inhalation procedures.

    The inhalation form of release is called Fluimucil antibiotic IT and differs from regular Fluimucil in its composition. In addition to acetylcysteine, the drug contains the antibiotic thiamphenicol. Therefore, Fluimucil antibiotic IT has a wider range of applications and provides the following therapeutic effect:

    • the antibiotic thiamphenicol effectively fights a wide range of bacterial microflora, suppressing its growth and reproduction in the respiratory tract;
    • acetylcysteine ​​thins viscous sputum, accelerates its elimination and facilitates the penetration of the antibacterial component into the lung tissue;
    • the drug provides a local anti-inflammatory effect;
    • activates immune cells of the respiratory system;
    • effectively clears mucus not only from the bronchi, but also from the paranasal sinuses;
    • does not lose its therapeutic effect even in the presence of purulent sputum.

    Thanks to a wide spectrum of therapeutic action, this combined drug for inhalation quickly alleviates the patient’s condition with a wide range of respiratory diseases caused by conditionally pathogenic and pathogenic microflora.

    Composition of Fluimucil IT

    The drug is available in the form of a yellow-brown mass (lyophilisate), which should be diluted with water for injection before use. After dilution, a clear, colorless solution is obtained, with a specific sulfuric odor, which is used for inhalation procedures.

    The package contains 3 ampoules of lyophilisate and solvent. Each bottle of the drug contains:

    Water is in separate bottles and is used as a solvent.

    Indications

    Since Fluimucil antibiotic IT exhibits anti-inflammatory, mucolytic and antibacterial effects, it is included in the complex therapy of the following diseases:

    • infectious and inflammatory lesions of the lower parts of the respiratory system (bronchitis, pneumonia, cystic fibrosis, whooping cough, emphysema, lung abscesses);
    • diseases of the upper respiratory tract and ENT organs (laryngotracheitis, otitis, rhinitis, sinusitis);
    • removal of viscous sputum in case of concomitant pulmonary infections (tuberculosis, in the presence of cavernous lesions);
    • in preparation for bronchoscopy;
    • in order to prevent complications after surgery (tracheostomy, thoracic surgery).

    In addition, the drug is recommended for use to relieve attacks of dry, painful cough that accompany acute respiratory infections.

    Methods of application

    Instructions for using the antibiotic Fluimucil IT for inhalation recommend that the procedure be carried out using a special medical device - a nebulizer. The device ensures the delivery of active substances directly to the pathological focus, which eliminates the negative impact of the drug on other organs and systems. During therapy, experts advise using a compressor nebulizer. The dosage of the solution and the duration of the course of treatment are determined by the doctor.

    How to dilute the antibiotic Fluimucil for inhalation?

    For the procedures to be successful and provide the desired result, it is necessary to properly prepare the solution. It is recommended to dilute the lyophilisate with water for injection, which is included with the drug. The solution must be prepared in a glass container; you should not pour it into a metal or plastic container, otherwise the oxidation reaction will negatively affect the effectiveness of acetylcysteine. Dilution of the drug is carried out as follows:

    • first, open the bottle with the lyophilisate, removing the metal cap and rubber stopper;
    • then, using a special file, open a glass ampoule with sterile water;
    • the contents of the ampoule with the solvent are poured into a bottle with powder and shaken until a clear, colorless solution is obtained.

    The standard dose of solution for adults for 1 procedure is 2 ml of solution. When diluting 1 bottle, 500 mg of dry substance is combined with 4 ml of solvent. The resulting solution is divided into 2 applications, inhalations are done in the morning and in the evening. Part of the solution is used immediately after dilution. The remaining dose in a closed bottle is stored in the refrigerator until the evening.

    The duration of each inhalation is 15 minutes. If the drug is used to treat sinusitis, otitis, frontal sinusitis, it is recommended to use a special nasal nozzle. When treating a strong, dry cough, it is best to spray the solution through a mouthpiece, which the patient takes into the mouth. Through the opening of the mouthpiece, the medicinal solution is supplied directly to the site of inflammation. In severe cases, the doctor may double the dosage of the drug.

    On average, the course of treatment takes from 7 to 10 days. If longer therapy is necessary, the doctor will decide on further use of the drug.

    Fluimucil antibiotic for inhalation for children

    The dosage of the solution for pediatric inhalation should be reduced by half. That is, no more than 1 ml of solution can be used for one procedure. To do this, the volume obtained from diluting one bottle is divided into 4 parts.

    Inhalations should not be performed if the child has a high fever. Before the procedure, you need to calm the baby down, explain the sequence of actions, and show him how to inhale the healing steam correctly.

    The prepared solution is poured into the inhaler and the procedure begins. The baby must inhale the drug particles through the nose, using a special cover that covers the nose and mouth. If the child is old enough, you can inhale using a nasal nozzle or inhale the medicinal solution through a mouthpiece.

    The treatment process should be approached with particular caution in newborns and premature babies. For them, any excess of the specified dosages can result in unwanted complications. A specialist should calculate the dose of the medicine, taking into account the severity of the pathology and the age of the patient. For serious respiratory ailments, the drug can be used in higher doses in the first 2-3 days of treatment. In the youngest patients, the duration of inhalation is only a few minutes; adolescents should inhale the therapeutic steam for at least 15 minutes.

    Contraindications

    There are few restrictions on the use of the antibiotic Fluimucil IT for inhalation. First of all this:

    • individual intolerance to the components included in the drug;
    • blood diseases or changes in indicators (thrombocytopenia, leukopenia, anemia).

    In addition, the medication should be prescribed with extreme caution in cases of bone marrow dysfunction, severe liver and kidney damage, acute peptic ulcers, bronchial asthma or pulmonary hemorrhages.

    In children under 2 years of age, due to the functional characteristics of the kidneys, the administration of this drug for inhalation procedures should be approached with special care, excluding exceeding the recommended doses. In case of overdose, it is possible to increase side effects and develop superinfection with an imbalance of bacterial microflora in the intestine.

    Adverse reactions

    The use of the drug may cause a number of side effects. Most often, during the procedure, children experience nausea, which is associated with the specific, not very pleasant smell of the drug.

    Sometimes there may be irritation of the mucous membrane of the respiratory tract, the appearance of a reflex cough and runny nose, and the appearance of symptoms of stomatitis. Allergic reactions to the drug are also possible, so before using the solution for the first time, doctors strongly advise you to do an allergy test. In isolated cases, a complication such as bronchospasm is possible; to eliminate it, a bronchodilator is used, which relaxes the muscles of the bronchi.

    Additional recommendations

    Inhalations with the drug Fluimucil IT cannot be combined with taking tetracycline antibiotics and Ampicillin, since these drugs neutralize the therapeutic effect of the procedure.

    The simultaneous use of Fluimucil with antitussives is prohibited. As a mucolytic, the drug thins sputum, and drugs that block the cough reflex prevent its removal from the body. As a result of stagnation of mucous secretion, the risk of developing purulent complications and pneumonia increases significantly.

    Another recommendation concerns elderly patients. For this category of patients, the drug is used in a minimal dosage.

    Analogs

    Fluimucil with an antibiotic has no structural analogues, but this drug can be replaced with other agents with a similar mucolytic effect. For example, to thin sputum, a doctor may prescribe solutions or syrups of ACC, Mukobene, Ambrobene, Ambroxol, Lazolvan.

    If you are intolerant to the components of Fluimucil IT, the specialist will select other solutions for inhalation procedures with an antibacterial component that will not provoke an allergic reaction.

    Fluimucil IT antibiotic can be purchased at a pharmacy without a doctor's prescription, but before purchasing it, be sure to consult with a specialist to identify possible contraindications and clarify the rules for using the drug. The average price for a package of the drug containing 3 bottles of lyophilisate varies from 420 to 580 rubles.

    Reviews about the application

    I would like to say a huge thank you to the manufacturer of Fluimucil with antibiotic, which is intended for inhalation. An excellent drug that has helped my child out more than once and saved him from bronchitis and pneumonia. My daughter was born prematurely and often suffered from respiratory diseases.

    When I started kindergarten, I had to take sick leave almost every month. Constant bronchitis, dry, exhausting cough and the threat of complications - this condition has already become commonplace. They treated him with various means, but the effect was short-lived until they tried inhalations with Fluimucil.

    It contains two components - an antibiotic and an agent that thins thick sputum. The child enjoyed breathing medicinal steam through an inhaler, because there was no need to take bitter tablets and powders. Relief came already on the second day, the cough softened, and the sputum was intensively removed. As a result, the child was soon on the mend. After some time, we noticed that the baby began to catch colds and get sick less often, and in the summer they tried to carry out hardening procedures. Now he is a completely healthy and active child who practically does not get sick.

    Marianna, Nizhny Novgorod

    Review #2

    Last year I suffered from sinusitis. It all started with a common cold and a bad runny nose. I dealt with the fever and other unpleasant symptoms quickly, but my nose was running for several weeks. When I began to suffer from headaches, heaviness in the head and purulent discharge from the nose, I had to consult a specialist, who diagnosed sinusitis.

    The doctor advised to include inhalations with Fluimucil in the treatment. I just had a nebulizer at home and started doing procedures. It was after inhalations that I noticed an improvement in my condition and quickly began to recover. The tablets prescribed by the doctor destroyed the infection from the inside, and procedures with Fluimucil helped liquefy the viscous mucus and remove it from the sinuses.

    Review #3

    I recently discovered a new drug – Fluimucil antibiotic IT. In winter I often catch colds, so bronchitis has long become chronic for me. As soon as I freeze, a dry, exhausting cough immediately begins, which torments me for several weeks, depriving me of rest and sleep. I treat myself mainly with folk remedies; I don’t like taking pills and other synthetic drugs.

    They have many contraindications; they kill the liver and kidneys. Once again, during a visit to the pharmacy, the pharmacist advised me to buy Fluimucil and inhale with it. I have a nebulizer and decided to try it. The drug is quite expensive, but it has few contraindications, and inhalation does not have a toxic effect on internal organs, because the medicine does not enter the stomach, but is sprayed into the respiratory system. I really liked the result, I got rid of my cough in just 5 days, and didn’t feel any side effects.

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    Before using medications, consult your doctor!

    Source: http://glavvrach.com/fluimucil-2/

    Instructions for use of fluimucil antibiotic it for inhalation + reviews

    The drug Fluimucil antibiotic IT is considered one of the most effective antimicrobial drugs for the treatment of various respiratory infections. Most often it is prescribed for use in the form of inhalations, although the solution can also be used by injection. The medicine quickly eliminates unpleasant symptoms, and, for moderate diseases, one package is enough for a full three-day course of antibiotic therapy for a child or adult.

    Fluimucil antibiotic IT for inhalation - instructions for use

    From the name it becomes clear that this is not just a cough remedy, but a serious antimicrobial drug that can only be used as prescribed by a doctor. It has a number of contraindications and restrictions on use that must be taken into account to avoid complications or side effects. The following instructions for use for inhalation Fluimucil antibiotic IT will help you understand its composition, purpose and features of use, as well as assess all the risks of self-medication.

    Composition of the drug

    The medicine contains two main components that have a comprehensive effect on the cause and symptoms of the disease. The first of them, thiamphenicol, is one of the representatives of the group of amphenicol antibiotics that exhibit bacteriostatic activity against pathogenic microorganisms. The spectrum of antimicrobial action of Fluimucil antibiotic IT includes:

    • gram-positive pneumo- and streptococci, diphtheria bacillus, clostridia and listeria;
    • gram-negative Salmonella, Neisseria, Escherichia coli, Shigella, Yersinia, Brucella and Bacteroides.

    The growth and reproduction of pathogenic microflora is stopped due to the suppression of protein synthesis in cells.

    The second component - acetylcysteine ​​- is a mucolytic, that is, it thins sputum, thereby facilitating its discharge. It also enhances the therapeutic effect of the antibiotic, facilitating its penetration into the lung tissue, and prevents bacteria from attaching to the mucous membranes of the respiratory tract.

    Release form

    Fluimucil antibiotic IT is a product of the Italian pharmaceutical company ZAMBON SpA. It is produced in the form of a special substance (lyophilisate), from which a solution for injections, rinsing or inhalation is prepared by dilution. The active substances thiamphenicol and glycinate acetylcysteinate are contained in an amount of 810 mg for each of the three bottles in the package (500 of which are antibiotic). There are also 3 ampoules with 4 ml of solvent - water for injection. The lyophilisate also contains the auxiliary component disodium edetate.

    Photo Fluimucil - IT antibiotic

    Indications and contraindications for use

    Fluimucil is an antibiotic in combination with a mucolytic, which has a pronounced therapeutic effect in case of damage to the respiratory system by strains of pathogenic bacteria that are sensitive to it. When administered by inhalation, thiamphenicol tends to accumulate in the respiratory tract, penetrating into tissues. The mucolytic is also quickly and evenly distributed. It is recommended to use the drug in the following cases:

    • ENT diseases (otitis and sinusitis), inflammation of bacterial origin in the upper parts of the respiratory system;
    • infections of the bronchial tree and lungs, which include chronic and acute forms of inflammatory processes in the bronchi, prolonged pneumonia, whooping cough, cystic fibrosis, lung abscess and empyema;
    • treatment and prevention of the consequences of various medical procedures in the respiratory tract (for example, tracheostomy, bronchoaspiration) and thoracic operations;
    • concomitant infections (including those caused by mycobacteria) in order to activate drainage.

    Since the drug contains an antimicrobial component, it has some restrictions and prohibitions on use. Fluimucil antibiotic IT is contraindicated in the case of pathologies of the hematopoietic system, which are manifested by leuko- and thrombocytopenia, anemia. In addition, the medicine cannot be prescribed to patients with individual intolerance to any of the components of the drug.

    During pregnancy, use is possible only if there is no effective alternative and the benefit to the woman predominates over possible teratogenic risks. Nursing women who are prescribed Fluimucil IT antibiotic should temporarily stop breastfeeding and regularly express milk (in order to maintain lactation).

    A history of diseases such as renal and liver failure requires careful use of the drug. In addition, due to age-related characteristics of the excretory system, the use of the drug in children under 3 years of age is limited (strictly as prescribed by a doctor). It is not allowed to increase the dosage in the case of antibiotic therapy for persons over 65.

    Dosages, treatment regimens and overdose

    Fluimucil antibiotic IT in the form of inhalation is recommended to be used 1 or 2 times a day, after diluting the lyophilisate according to the instructions with the solvent included in the kit. The maximum duration of antibiotic therapy should not exceed 10 days. The daily dose is usually 500 mg of the active substance (1 bottle of ready-made solution) for adults and 250 mg for children, divided into 2 doses.

    Fluimucil antibiotic is dripped into the nose or ear for diseases of the relevant organs (2-4 drops), used as intramuscular injections. In the latter case, adults are prescribed 500 mg twice or thrice a day, and for children the required amount of the drug is determined according to age. For example, premature infants and infants up to 2 weeks - 25 mg/kg per day, children under three years old - 125 mg twice a day, up to seven - 250 mg and over 7 - the same dose, but three times a day. In special cases (severe course of the disease), it is permissible to double the dosage in the first 3 days,

    In a hospital setting, the solution is used to rinse cavities, introduce into the paranasal sinuses or endotracheally into the respiratory tract. This is done both for the purpose of treating bacterial infections and for prevention after surgical interventions and other medical procedures. The drug is diluted in the same way, used in an amount of 1 or 2 milliliters per administration.

    If the recommended doses are exceeded, the composition of the bacterial microflora changes and signs of superinfection appear. The severity of side effects increases (with the exception of allergic manifestations). To combat the consequences of an overdose, maintenance drug therapy should be used.

    Side effect

    Inhalations using the drug Fluimucil antibiotic IT sometimes cause negative responses from the body. This may be allergies, nausea, reflex cough, runny nose, stomatitis, local irritation of the mucous membrane. In case of bronchospasm, special bronchodilator drugs should be used. Intramuscular injections are fraught with pain and a burning sensation at the injection site, as well as a change in the blood formula towards a decrease in such formed elements as red blood cells, platelets and leukocytes.

    How to dilute the antibiotic Fluimucil IT for inhalation for children

    It is quite easy to prepare the drug yourself. To do this, you need to open the bottle of powder and pour one of the included 4-ml ampoules of water for injection into it using a sterile syringe. The resulting solution contains 500 mg of antibiotic, which is the daily dose for an adult. It is used in 2 doses, and the remainder is stored in the refrigerator in a closed bottle until the next use.

    For children, the recommended single dose of the drug Fluimucil antibiotic IT is half as much, therefore, after the described dilution of the lyophilisate with sterile water, proceed as follows:

    • draw a quarter of the volume of the prepared solution (1.25 ml) into a syringe (without a needle) from the bottle;
    • add 1 milliliter of pharmaceutical saline solution there;
    • Place the finished mixture in a compressor nebulizer.

    The tightly sealed bottle of the prepared medicine should be stored in the refrigerator until the next use. The solution should not come into contact with metal or rubber surfaces.

    special instructions

    When using the drug Fluimucil antibiotic IT, you should take into account not only contraindications and restrictions, but also some other features. So, you should not allow it to come into prolonged contact with metal or rubber. In addition, during antibiotic therapy there is no need to use any antitussive systemic drugs or sprays. They lead to stagnation of sputum and slow down the healing process.

    Reviews – Fluimucil antibiotic IT for inhalation

    Patients' opinions about this drug are quite contradictory. Its only quality regarding which buyers are unanimous is its rather high cost (in pharmacies it is sold at a price of 650 rubles for one pack with three bottles). In addition, many note a specific bitter taste, which irritates the respiratory tract and can even cause nausea.

    As for effectiveness, opinions are divided on this issue. About half of patients report excellent treatment results and rapid disappearance of symptoms. There are reviews that Fluimucil IT antibiotic helped get rid of severe forms of sinusitis, sinusitis and nasopharyngeal diseases. The rest express dissatisfaction with the lack of results, but, as a rule, there is no mention of any severe side effects.

    Reviews of Fluimucil IT antibiotic for inhalation for children are in most cases positive. Many parents characterize it as a highly effective remedy for bronchitis, laryngotracheitis and rhinitis of bacterial origin. Since the medicine acts locally, there are practically no complaints about side effects.

    This difference in the evaluation of the drug is presumably explained by the approach to the treatment of adults and children. Parents are more responsible, so they rarely show independence in such serious matters and follow the advice of a specialist. The pediatrician objectively assesses the need for the drug and prescribes the optimal dosage and course of antibiotic therapy.

    Adults often self-medicate, without visiting a therapist, trying to cure a viral infection with an antibacterial agent, which in this case is completely ineffective. Thus, it is imperative to consult a doctor who will accurately determine the cause of the disease and recommend adequate drug therapy.

    Trust your health to professionals! Make an appointment with the best doctor in your city right now!

    A good doctor is a general specialist who, based on your symptoms, will make the correct diagnosis and prescribe effective treatment. On our portal you can choose a doctor from the best clinics in Moscow, St. Petersburg, Kazan and other Russian cities and receive a discount of up to 65% on your appointment.

    * Clicking on the button will take you to a special page on the site with a search form and an appointment with a specialist of the profile you are interested in.

    * Available cities: Moscow and region, St. Petersburg, Ekaterinburg, Novosibirsk, Kazan, Samara, Perm, Nizhny Novgorod, Ufa, Krasnodar, Rostov-on-Don, Chelyabinsk, Voronezh, Izhevsk

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