Flemoxin and flemoxin solutab difference

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Flemoxin and Flemoklav - is there a difference between the two drugs?

It is important to treat diseases of bacterial etiology efficiently and in a timely manner. Antibacterial drugs based on amoxicillin are excellent for this purpose.

Table of contents:

They not only help in a short time to stop the adverse effects of microflora on the body, but also completely destroy it.

Today, the antibiotic market is filled with a huge number of drugs that differ in potency and other characteristics. In today's material, our resource decided to take a closer look at such popular medications as Flemoxin and Flemoklav, and also highlight the most significant differences between them.

Flemoxin Solutab - composition, properties and release form

Flemoxin Solutab is a broad-spectrum antibacterial agent

Before analyzing the effects of drugs on the human body and highlighting the differences between them, it would be a good idea to consider each antibiotic separately. Let's start looking at medications with Flemoxin.

So, the trade name of this antibiotic looks like “Flemoxin Solutab”. The drug belongs to the group of antibacterials based on the active substance “amoxicillin” (the pharmacological group of the drug is penicillin, semi-synthetic antibiotics). Flemoxin is produced in white or slightly yellow tablets, which have an oval shape and an image of the manufacturer’s logo, as well as a digital designation. The latter is identification and indicates how much active substance the tablet contains.

Digital identification has the following grouping:

The tablets are sorted into rectangular packages and similar blisters, which contain 5 tablets each and are presented in 2 or 4 copies.

The active ingredient in the drug "Flemoxin Solutab" is represented by amoxicillin, which is contained in the drug in the dosages mentioned above.

In addition, the drug contains dispersible cellulose, microcrystalline cellulose, crospovidone, vanillin, saccharin, magnesium stearate and some flavorings.

The properties of Flemoxin Solutab are standard for its pharmacological group. In simple terms, this drug stops the development of the bacterial microflora that caused the disease, and over time reduces its adverse effects on the patient’s body to a minimum. Thanks to this, the antibiotic is accepted for its excellent bactericidal properties all over the world.

More information about the drug Flemoxin Solutab can be found in the video:

You can take Flemoxin Solutab for pathologies of bacterial etiology in such human organs as:

  • respiratory system organs
  • genitourinary system organs
  • organs of the gastrointestinal tract
  • leather and other soft tissues

It is important to take the drug taking into account the recommendations of the treating specialist and the background information provided in the instructions for the antibiotic. It is in the latter that you can learn in more detail about contraindications, dosages and other things related to Flemoxin Solutab.

Flemoklav Solutab - composition, properties and release form

Flemoxin Solutab effectively treats respiratory diseases caused by bacterial infection

Flemoklav Solutab, in turn, is not much different from its opponent in terms of release form. This antibiotic is also available in tablets similar in size to Flemoxin. However, the tablets are divided into 4 per blister, which can be from 4 to 8 in one package. At the same time, Flemoklav contains slightly less active substance (the same amoxicillin) than in the previously considered drug.

Depending on the form of release, the antibiotic may contain from 125 to 875 mg of active substance, supplemented by an appropriate dose of a special substance - clavulanic acid.

The composition of Flemoklav Solutab includes:

  • active substance – amoxicillin trihydrate
  • clavulanic acid
  • microcrystalline cellulose
  • vanillin
  • saccharin
  • magnesium stearate
  • flavorings

Similar to Flemoxin, Flemoklav has antibacterial properties with a wide spectrum of effects, since both drugs belong to the same pharmacological group - penicillin, semi-synthetic antibiotics.

Despite this similarity, the medication is taken in fewer situations.

Thus, Flemoklav is widely used in the treatment of the following pathologies:

  • respiratory diseases
  • diseases of the genitourinary system
  • lesions of the skin and soft tissues
  • rarely – gastrointestinal pathologies

The dosage for use is determined solely by the doctor based on the severity of the disease and the age of the patient. It is worth understanding that correct use is a fundamental factor in successful therapy, therefore it is necessary to take Flemoklav taking into account the recommendations of the treating specialist and the manufacturer of the drug. You can find out about contraindications, expiration dates and similar things about a medication by carefully reading the instructions for it.

Flemoxin and Flemoklav - what is the difference?

It would seem that after receiving general information about both Flemoxin and Flemoklav, it is extremely difficult to identify any differences between the drugs. However, this is a rather erroneous judgment, since, delving into the study of antibiotics more deeply, a number of differences can be identified between them. Our resource has carried out this procedure and is ready to present you with its results.

First of all, we note that Flemoclav Solutab contains clavulanic acid, but its opponent does not. This difference makes the first antibiotic more resistant in the fight against bacterial microflora, since it is clavulanic acid that binds to bacterial beta-lactamases, which helps protect the antibiotic from the adverse effects of particularly strong microorganisms and their enzymes that can destroy the drug and neutralize its effects. Such a minor nuance puts Flemoklav Solutab in a more honorable position relative to his today's opponent.

In addition, the combined use of clavulanic acid and amoxicillin allows Flemoclav to provide additional benefits:

  • increase the versatility of the drug, that is, this antibiotic is able to fight a larger list of bacteria than its opponent - Flemoxin
  • reduce the dose of the antibiotic taken, since amoxicillin is supplemented with an appropriate dose of clavulanic acid (for example, 250 + 62.5 Mg or 875 + 125 Mg)

Despite the smaller list of pathologies for the treatment of which Flemoklav is used, it is more universal, especially in the treatment of respiratory tract pathologies. It is worth noting that both drugs we are considering are produced by the same pharmacological company from Holland. In fact, they are close analogues with slight differences in composition, which modify the method and effect of the drugs.

Comparing the statistical data collected by specialists regarding treatment with Flemoxin and Flemoclav, the following can be highlighted:

  • When using the first antibiotic, about 50% of people notice a noticeable effect from the drug
  • when using a medication containing clavulanic acid, this effect is noted by more than 60% of patients

There are no other differences between the drugs, except for their cost. On average, Flemoklav costs % more than its opponent when used in similar situations.

Do not forget that both antibiotics are quite potent and should not be prescribed for self-medication by the patient himself or his relatives.

Which of them is most optimal for use in a particular case can only be determined by the attending physician who has the necessary information about the pathology and clinical picture of the patient’s illness. Improper organization of antibacterial therapy is a dangerous practice that can cause some complications in the patient, remember this.

Summarizing today's material, we note that Flemoxin and Flemoklav are highly soluble and very similar antibiotics, but they still have differences between themselves. The most significant of these is the general principle of influencing unfavorable microflora. It can be stated that Flemoclav is a more universal antibiotic that will perform slightly better than its opponent. Despite this, the final choice between two drugs should be made only by the treating specialist, taking into account all the characteristics of the patient’s disease. We hope that the previously presented material was useful to you. Good luck in treating your illnesses!

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The medical information published on this page is strictly not recommended for self-medication. If you feel negative changes in your health, immediately contact an ENT specialist. All articles published on our resource are for informational purposes only. If you use this material or a fragment of it on your website, an active link to the source is required.

Source: http://tvojlor.com/lekarstva/flemoksin-i-flemoklav-otlichie.html

Flemoxin and Flemoklav - what is the difference?

When the cold season begins, every person thinks about choosing an effective medicine.

The complex of treatment for colds always includes an antibacterial drug. Some of the most common drugs in this group are Flemoklav solutab and Flemoxin solutab. These drugs are in great demand in medicine; you can buy them at any pharmacy and the packaging is very similar in appearance. Now he’ll try to figure out whether Flemoxin Solutab or Flemoklav - which is better?

To make a choice in someone’s favor, let’s consider how Flemoxin Solutab differs from Flemoklav Solutab.

Flemoklav Solutab

The drug is aimed at treating the respiratory system, which is caused by a bacterial infection. Flemoxin comes in the form of tablets. The active substance is amoxicillin. The dosage of the active ingredient depends on the form of release. The antibacterial agent may contain from 125 to 875 mg of the active component. The active substance is supplemented with a special component. It's called clavulanic acid.

Flemoklav is an antibiotic with a broad spectrum of action. Like Flemoxin, Flemoklav is part of the same pharmacological group - penicillin, semi-synthetic antibiotics.

Flemoklav is prescribed for:

  • respiratory tract diseases;
  • ailments of the genitourinary system;
  • lesions of the gastrointestinal tract.

Only the doctor who is seeing the patient can determine the required dosage, based on the severity of the disease and age.

Amoxicillin and clavulanic acid can develop a number of adverse reactions. Often, patients complain of stomach pain, vomiting, diarrhea, dyspepsia, flatulence and dryness of the oral mucosa. This drug can be prescribed to pregnant women. Clavulanic acid and Amoxicillin do not adversely affect intrauterine development. But in any case, in the first months, doctors try to replace Flemoklav with a more gentle drug. If, according to indications, a woman needs to undergo a course of treatment during breastfeeding, then it would be good to temporarily transfer the child to artificial feeding.

If you take Flemoklav according to all the rules, you can achieve quick positive results. To do this, you need to listen to all the doctor’s recommendations and carefully study the description of use.

Flemoxin contains amoxicillin. It is the active ingredient and exhibits resistance to trihydrate compounds. Amoxicillin is part of the group of semisynthetic penicillins. Their chemical spectrum and active structure are similar to Ampicillin.

Flemoxin consists of additional components, namely a chemical substance that ensures solubility in minimal volumes. Chemical substances include cellulose and microcrystalline cellulose.

To remove the bitterness in the tablets, pharmacists added special flavorings. Thanks to them, the tablets became pleasant in taste, reminiscent of the taste of tangerine and lemon.

This drug is also available in tablet form. Their color can be white or light yellow. Color may vary due to cellulose dosage.

Doctors can prescribe Flemoxin for children. Therefore, pharmacists have created special children's tablets with a lower dosage of the active substance. But it is very difficult to give a tablet to a small child, and Flemoxin is not available in powder form. Although, all oral antibiotics are produced in this form.

The attending physician can prescribe a drug to a woman during pregnancy, but only if the positive results outweigh the risk of adverse reactions.

The active substance flemoxin easily penetrates the placental barrier and is excreted in breast milk during lactation. This may cause sensitization in the newborn.

Side effects may include nausea, vomiting, and loss of taste buds. Also, due to individual intolerance to the active substance, the patient begins to experience allergic reactions in the form of skin rashes.

Release form of Flemoxin:

  • Flemoxin Solutab - dosage 125 mg;
  • Flemoxin Solutab - dosage 250 mg;
  • Flemoxin Solutab - dosage 500 mg;
  • Flemoxin Solutab - dosage 1000 mg.

What is the difference between Flemoxin and Flemoklav?

The chemical structure of amoxicillin is almost the same as ampicillin. It has the same spectrum of antibacterial actions. But there is one main difference - amoxicillin is more easily absorbed, thereby ensuring a higher level of the active component in the blood.

Penicillins, ampicillins, oxacillins, amoxicillins are beta-lactam antibiotics, that is, the structure of their molecules contains a beta-lactam ring. Because of this, they act identically on bacterial cells. The mechanism of action lies in the chemical structure: the antibiotic binds to the active center of the enzyme. A kind of catalytic exchange of peptidoglycan occurs. Peptidoglycan is an important component of bacterial cell walls. If the body produces it, then the division process is completed. When bacteria reproduce, one parent cell divides into two daughter cells. But, if peptidoglycan synthesis is inhibited, then the new cell does not receive its own separate place and is not separated from the parent. Because of this, two cells die.

Why then invent a combination drug if everything is so easy? Every pathogenic microorganism has a natural protective barrier. The process of evolution has developed special enzyme substances in them, these are beta lactamases.

So, what is the difference between these two drugs? Flemoclav contains not only amoxicillin, but also clavulanic acid. Beta-lactamases bind to clavulanic acid and inactivation begins. Therefore, the active component is not damaged by enzymes and exerts its antibacterial effect.

What is better Flemoxin or Flemoklav?

Above, we examined the compositions of these two drugs and determined that Flemoklav better fights pathogenic microorganisms that produce beta-lactamases. Meanwhile, Flemoxin does not resist these bacteria. But, more often, Flemoxin copes with infectious diseases.

If doctors have not diagnosed the disease, namely its causative agent, then it is better to take Flemoklav. The drug has a great chance of coping with infectious diseases of an inflammatory nature. In addition, clavulanic acid in some situations reduces the concentration of the antibiotic and increases effectiveness.

Although antibiotics have become popular, they have one negative effect - they negatively affect the microflora of the human body.

Therefore, doctors do not recommend taking antibiotics on your own. It is better to leave the choice to your doctor.

Also, the doctor will help you choose one of the two medications under consideration.

What is the difference between Flemoklav Solutab and Flemoxin Solutab?

Flemoxin Solutab contains one active ingredient - amoxicillin, and Flemoklav consists of two active ingredients - amoxicillin and clavulanic acid.

Due to the fact that Flemoklav contains clavulanic acid, the drug is considered more active.

If you compare the price, then Flemoklav is two times cheaper than Flemoxin.

If you decide to choose one of the medications that are not particularly different from each other, then first consult with your doctor. Self-medication can negatively affect your health.

Source: http://wmedik.ru/zabolevaniya/urologiya/flemoksin-i-flemoklav-v-chem-raznica.html

Flemoxin and Flemoklav - what is the difference?

Thanks to the discovery of antibiotics, many diseases have ceased to be deadly. Over the last century, many antibacterial agents have been synthesized, but amoxicillin, first introduced into clinical practice in the 70s, is still one of the widely used antibiotics. Its importance is so great that the drug has been listed by the WHO as an essential medicinal substance needed in the basic health care system of all countries. Let's compare modern antibiotics based on amoxicillin, which can be found in our pharmacies.

What is the difference between Flemoklav and Flemoxin?

There are contraindications, use only after consulting a doctor

The antibiotics contain the same active ingredient - amoxicillin . However, Flemoklav contains an additional active agent - clavulanic acid . Therefore, the pharmacological groups to which the drugs belong are different. Thus, the usual one belongs to the pharmaceutical group of penicillins, and Flemoklav belongs to penicillins in combination with beta-lactamase inhibitors.

Both drugs are products of Astellas Pharma Inc. (Netherlands) and are available in the form of easily dissolving tablets, as emphasized in their name (“Solutab”). But, if you compare other characteristics of the drugs, there is a difference in the dosage of amoxicillin.

Flemo xin is produced in the following dosages:

  • 125 mg;
  • 250 mg;
  • 500 mg;
  • 1000 mg.

Flemo Clav has the following dosages of amoxicillin plus a proportional amount of clavulanic acid (indicated in parentheses):

  • 125 + (31.25) mg;
  • 250 + (62.5) mg;
  • 500 + (125) mg;
  • 875 + (125) mg.

Difference in Action

In terms of its chemical structure, amoxicillin is closest to ampicillin. It has the same spectrum of antibacterial action, but unlike ampicillin, it is 40-60% better absorbed when taken per os (orally) and thus provides a higher concentration of the active substance in the blood.

Antibiotics of this series (penicillin, ampicillin, oxacillin, amoxicillin, etc.) are also called beta-lactams, because in the structure of their molecule they contain the so-called beta-lactam ring. Therefore, their mechanism of action on a bacterial cell is similar. It lies in the fact that, thanks to this chemical structure, the antibiotic binds to the active center of the enzyme that catalyzes the synthesis of peptidoglycan.

Peptidoglycan is a vital component of the bacterial cell wall. If it is not produced, the bacteria cannot complete the division process. When bacteria multiply, two daughter cells arise from one parent cell. However, when peptidoglycan synthesis is inhibited, the new cell will never receive its own “separate apartment” and will not bud off from the parent. As a result, both cells die.

If the mechanism is so simple and reliable, why come up with combination drugs? This is necessary because bacteria have natural protection. During evolution, they developed beta-lactamase enzymes that hydrolyze beta-lactam antibiotics.

So, Flemoklav, in addition to amoxicillin, contains clavulanic acid. This substance irreversibly binds to beta-lactamases and inactivates them. As a result, the antibiotic is saved from the damaging effects of the enzyme and can achieve its antibacterial effect.

"Solyutab" - packages of 250, 500 and 875 mg

What's better?

According to the differences in composition, the difference will also be observed in their therapeutic effect. Flemoxin cannot effectively fight bacteria that can produce beta-lactamases.

But the introduction of clavulanic acid into the composition of Flemoklav allows you to achieve the following advantages:

  1. expand the list of sensitive microorganisms (and therefore expand the indications for use);
  2. reduce the dose of antibiotic;
  3. increase the clinical effectiveness of the drug.

Thus, a combined antibiotic is the drug of choice in cases where the pathogenesis of the disease is due to the presence of microorganisms that produce beta-lactamases, namely when:

Many studies have been conducted to find the optimal combinations of amoxicillin and clavulanate. Nowadays, the ratios most often used in pharmaceuticals are 14:1, 7:1, 4:1, 2:1. In the drug Flemoklav, the ratio is 4 or 7 parts of antibiotic to 1 part of inhibitor.

A comparative evaluation of the effectiveness made it possible to establish that in the treatment of reactive arthritis in children, after only a month of taking amoxicillin in combination with clavulanate, an improvement was observed in 58% of patients compared to 48% of patients in the group taking only amoxicillin.

Observations in operative dentistry have shown that taking a combination of amoxicillin + clavulanate shortens the recovery period after surgery, relieves swelling faster and reduces the subjective feeling of pain compared to a single antibiotic.

The use of amoxicillin in combination with clavulanate as part of combination therapy for peptic ulcer disease associated with Helicobacter pylori resulted in recovery in 92% of patients, while the rate in the group taking only amoxicillin was 85%.

However, simple and combined antibiotics differ not only in their therapeutic properties, but also in their safety profile. The fact is that clavulanate can cause adverse reactions on its own, regardless of amoxicillin. This increases the list of contraindications and increases the risk of side effects when taking Flemoklav.

Clinical trial data indicate a higher incidence of gastrointestinal symptoms (diarrhea, vomiting, nausea) after taking the combination drug. Retrospective studies show that liver disease is 6 times more common in patients taking clavulanate-based drugs. Therefore, you should not make a decision on your choice without consulting a doctor and testing. Otherwise, you can cause harm to your health, and you will never be cured of pathogenic bacteria.

Can these antibiotics be used for children?

With a doctor's prescription, of course, yes. According to the instructions, Flemoklav Solutab can be prescribed to children starting from 3 months of age. The daily dose for them is 20–30 mg amoxicillin/kg body weight.

The daily dose of Flemoxin for children under 1 year of age is 30–60 mg amoxicillin/kg body weight.

Cost difference

When treating mild/moderate infections, an adult needs to take 1–1.5 g of the drug per day, the duration of use is 7 days. The dose is divided into 2-3 doses. Let's calculate how much a course of treatment with tablets with a dosage of amoxicillin of 500 mg will cost.

The daily dose will be 3 tablets, 21 will be needed per week. 20 tablets of Flemoxin costs from 335 to 380 rubles. The same package of Flemoclav will cost approximately 15% more.

Source: http://www.kliwi.ru/2016/12/flemoksin-i-flemoklav-v-chem-raznica.html

What is the difference between amoxicillin and flemoxin solutab

Amoxicillin

Average price – 70 rubles

Amoxicillin is a broad-spectrum antibacterial agent that most effectively fights gram-positive microflora. The principle of action of the drug is to destroy the cell membrane of the microbe. The drug is prescribed for the treatment of:

  • Diseases of the genitourinary area (cystitis, urethritis, gonorrhea, pyelonephritis)
  • Diseases of the upper and lower respiratory tract (tonsillitis, bronchitis, pneumonia)
  • In combination with other antibiotics, the drug is used in the treatment of stomach ulcers.
  • Leptospirosis
  • Meningitis
  • Sepsis
  • Endocarditis
  • Salmonellosis
  • Lyme disease.

Available in the form of tablets, capsules and granules for diluting a suspension. The suspension is used in children, and in adults - other forms of release.

Flemoxin solutab

Average price - 300 rubles

Flemoxin solutab is an antibacterial drug that is a generic version of amoxicillin. It is a semi-synthetic penicillin and has a wide spectrum of effects. Destroys bacterial cell walls. It works best against gram-positive and gram-negative flora. It has the worst effect against staphylococci, Helicobacter pylori, and Proteus. The drug is prescribed for the treatment of:

  • Various infectious lesions of the respiratory tract (pharyngitis, otitis media, sinusitis, bronchitis, pneumonia, tonsillitis)
  • Urogenital infections (pyelonephritis, cystitis, cervicitis, urethritis, endometritis)
  • Infectious skin lesions (erysipelas, impetigo, dermatoses)
  • Gastrointestinal diseases (typhoid, peritonitis, dysentery, salmonellosis, cholecystitis).

Available in tablet form. Used in children from a very early age according to strict dosage calculations.

What is the difference

Flemoxin Solutab is distinguished by the fact that it is a generic version of its predecessor and has a special structure, with the help of which the drug can be absorbed more quickly in the gastrointestinal tract. Amoxicillin, not having such a structure, may partially degrade and lose its antibacterial properties.

Also, Flemoxin Solutab, due to its special property, has a higher cost. It is believed that Flemoxin Solutab is more suitable for children, and amoxicillin for adults.

What is better to choose

It is not recommended to choose antibiotics on your own or prescribe medications for treatment. In the presence of any disease, only a person with a medical education has the right to prescribe medications for treatment. These two medications are almost the same, in fact - they are analogues of each other, but still, if we compare the effectiveness of these drugs, then Flemoxin Solutab will be much better than regular amoxicillin.

Roughly speaking, the first remedy is a more improved analogue of its predecessor. The developers eliminated the main disadvantages of the predecessor antibiotic, but at the same time retained its full effectiveness. The bioavailability of flemoxin is significantly higher than that of amoxicillin. There are significantly fewer side effects, and the product is also less susceptible to the effects of gastric juice, which makes it safer for the mucous membrane.

Flemoxin solutab for otitis media

Otitis is an infectious disease that affects the ear. There is otitis media of the middle ear, external and internal. The disease is caused by the proliferation of pathogenic microflora, which provokes an inflammatory process. In its acute form, the disease causes pain and excruciating discomfort, which is impossible to cope with without additional medications.

Flemoxin solutab, along with some other antibacterial agents, is one of the most effective drugs for the treatment of otitis media in adults and children. It can be drunk regardless of meals, at any time of the day. This medication is good for otitis media in that it effectively penetrates the mucous membranes, bones and secretions. That is, the active ingredient of the drug penetrates well into pus and sputum, promotes their rapid removal from the body, so it is excellent for the treatment of otitis media. Due to the lower risk of side effects, this antibiotic is actively used in children.

For otitis media, dosages are strictly individual and are selected depending on gender, age and kidney health. You should take the drug for at least 5-10 days, depending on the doctor’s prescription. After all the main symptoms of the disease disappear, the medication is used for several more days in a row to completely eliminate the disease.

You should not take this drug if you are hypersensitive or have severe renal failure.

Source: http://lekhar.ru/lekarstva/antibakterialnye-preparaty/flemoksin-soljutab-i-amoksicillin-sravnenie/

The difference between flemoxin solutab and amoxicillin

Amoxicillin

Average price – 70 rubles

Amoxicillin is a broad-spectrum antibacterial agent that most effectively fights gram-positive microflora. The principle of action of the drug is to destroy the cell membrane of the microbe. The drug is prescribed for the treatment of:

Diseases of the genitourinary tract (cystitis, urethritis, gonorrhea, pyelonephritis) Diseases of the upper and lower respiratory tract (tonsillitis, bronchitis, pneumonia) In combination with other antibiotics, the drug is used in the treatment of the causative agent of stomach ulcers Leptospirosis Meningitis Sepsis Endocarditis Salmonellosis Lyme disease.

Available in the form of tablets, capsules and granules for diluting a suspension. The suspension is used in children, and in adults - other forms of release.

Average price - 300 rubles

Flemoxin solutab is an antibacterial drug that is a generic version of amoxicillin. It is a semi-synthetic penicillin and has a wide spectrum of effects. Destroys bacterial cell walls. It works best against gram-positive and gram-negative flora. It has the worst effect against staphylococci, Helicobacter pylori, and Proteus. The drug is prescribed for the treatment of:

Various infectious lesions of the respiratory tract (pharyngitis, otitis, sinusitis, bronchitis, pneumonia, tonsillitis) Infections of the genitourinary tract (pyelonephritis, cystitis, cervicitis, urethritis, endometritis) Infectious lesions of the skin (erysipelas, impetigo, dermatoses) Gastrointestinal diseases (typhoid, peritonitis, dysentery , salmonellosis, cholecystitis).

Available in tablet form. Used in children from a very early age according to strict dosage calculations.

Flemoxin Solutab is distinguished by the fact that it is a generic version of its predecessor and has a special structure, with the help of which the drug can be absorbed more quickly in the gastrointestinal tract. Amoxicillin, not having such a structure, may partially degrade and lose its antibacterial properties.

Also, Flemoxin Solutab, due to its special property, has a higher cost. It is believed that Flemoxin Solutab is more suitable for children, and amoxicillin for adults.

It is not recommended to choose antibiotics on your own or prescribe medications for treatment. In the presence of any disease, only a person with a medical education has the right to prescribe medications for treatment. These two medications are almost the same, in fact - they are analogues of each other, but still, if we compare the effectiveness of these drugs, then Flemoxin Solutab will be much better than regular amoxicillin.

Roughly speaking, the first remedy is a more improved analogue of its predecessor. The developers eliminated the main disadvantages of the predecessor antibiotic, but at the same time retained its full effectiveness. The bioavailability of flemoxin is significantly higher than that of amoxicillin. There are significantly fewer side effects, and the product is also less susceptible to the effects of gastric juice, which makes it safer for the mucous membrane.

Otitis is an infectious disease that affects the ear. There is otitis media of the middle ear, external and internal. The disease is caused by the proliferation of pathogenic microflora, which provokes an inflammatory process. In its acute form, the disease causes pain and excruciating discomfort, which is impossible to cope with without additional medications.

Flemoxin solutab, along with some other antibacterial agents, is one of the most effective drugs for the treatment of otitis media in adults and children. It can be drunk regardless of meals, at any time of the day. This medication is good for otitis media in that it effectively penetrates the mucous membranes, bones and secretions. That is, the active ingredient of the drug penetrates well into pus and sputum, promotes their rapid removal from the body, so it is excellent for the treatment of otitis media. Due to the lower risk of side effects, this antibiotic is actively used in children.

For otitis media, dosages are strictly individual and are selected depending on gender, age and kidney health. You should take the drug for at least 5-10 days, depending on the doctor’s prescription. After all the main symptoms of the disease disappear, the medication is used for several more days in a row to completely eliminate the disease.

You should not take this drug if you are hypersensitive or have severe renal failure.

When choosing between two drugs, it is better to trust a specialist. To decide which is better – amoxicillin or flemoxin, you should analyze them carefully. They are identical in properties and belong to the semisynthetic antibiotics of the penicillin group. The main component is amoxicillin trihydrate. It has an effect in relatively gram-negative and gram-positive microorganisms.

Although the drugs are identical, one is still better than the other for a number of reasons. To explain this difference, it is necessary to examine in more detail the composition of the drugs and their pharmacological action.

Amoxicillin is an antibacterial agent. It has a wide range of effects. The effect is noticeable against gram-positive microflora. The mechanism of action is based on the destructive ability of the cell membrane that exists in the microbe. The drug is actively prescribed for the treatment of the following diseases:

Genitourinary tract Upper and lower respiratory tract In combination with other antibiotics, used to combat stomach ulcers Meningitis Lyme disease Leptospirosis Salmonellosis Endocarditis Sepsis

The drug is sold in different forms - granules and capsules. To obtain a suspension, granules are needed; they are used in childhood. In adults, other types of the drug are used.

Flemoxin solutab is an antibacterial agent and a generic form of amoxicillin. It has a destructive effect on the bacterial cell walls. It has the greatest effect on gram-positive and gram-negative flora. In this respect, Flemoxin Solutab and Amoxicillin are similar. The least result is seen in the fight against staphylococci, proteus, and Helicobacter pylori. This remedy is used to treat the following pathologies:

Infections affecting the respiratory tract Infectious diseases in the genitourinary system Skin infections Gastrointestinal disorders

The drug is available as tablets. Can be used in children even at a very young age. The main thing is a clear dosage.

The main difference between Flemoxin Solutab is that it is a generic of the mentioned predecessor. It has a special structure that allows it to be quickly absorbed into the gastrointestinal tract. Amoxicillin does not have this structure, so it can break down and lose its antibacterial properties.

Another point why one drug may differ from another is price. Flemoxin has a higher cost. It is generally accepted that it is more suitable for children, and its analogue is more suitable for adults.

There is no need to choose any of these drugs on your own. Any medicine must be prescribed by a physician. The medications are almost the same, but one of them is better.

The effect of Flemoxin Solutab is better than that of regular amoxicillin. It is considered an improved version of its predecessor. Manufacturers have eliminated the shortcomings of the antibiotic, but the required effectiveness remains the same. Comparing bioavailability, in the case of flemoxin it is higher. There are fewer side effects and the product is less susceptible to the influence of gastric juice, so it is safe for the mucous membrane.

The drug can be divided into several parts, chewed and washed down with a small amount of water. When dissolved in water, a syrup with a citrus or vanilla aroma is obtained. The therapeutic effect does not disappear.

For adults and children over ten years of age and weighing over 40 kg, the drug should be taken 0.5 g tablet three times a day. In case of severe infection, the dosage is increased to 0.75 g - 1 g with the same frequency. In order to treat mild gonorrhea, three grams are prescribed for one-time use.

As for the fight against infectious diseases of gynecology and diseases of the gastrointestinal tract, biliary tract, it is necessary to take 1.5-2 g three times a day or 1-1.5 g four times a day. Leptospirosis is treated with a dosage of 0.5-0.75 g with the same frequency. Duration - from six to twelve days.

Carriers of salmonellosis take the drug 1.5-2 g three times a day for two to four weeks. After minor surgical operations and to prevent endocarditis, doctors prescribe 3-4 g to patients an hour before the procedure.

Regarding the use of Flemoxin, the important thing is that it can be taken during meals, before or after - it doesn’t matter. The dosage is selected individually, based on test results and general condition. The duration of administration is determined based on the nature of the bacteria that have infected the body. This usually takes about ten days. A couple of days after the condition improves, you can stop taking the drug. If there are any signs that the drug is not suitable, use should be discontinued.

Side effects are limited to intestinal symptoms. For example, nausea and diarrhea. An allergic reaction to the components included in the composition is possible.

When a doctor prescribes antibiotics, you should pay close attention to his recommendations, because the patient’s health and life may depend on it. Today we will try to figure out how one antibiotic differs from another, using the example of Flemoxin and Amoxicillin.

Amoxicillin is a semisynthetic antibiotic that has a strong bactericidal effect against gram-positive microbes. It acts directly on the cell membrane of the bacterium, destroying it. Used to treat diseases of the upper and lower respiratory tract, as well as urological and gynecological infections.

Flemoxin Solutab is a generic version of Amoxicillin. This is an acid-resistant antibiotic, it belongs to the group of semi-synthetic penicillins with a broad spectrum of action. The active ingredient is Amoxicillin, which is destroyed by penicillinase. In the body, the drug disrupts the support of the cell wall during cell growth and division. Retains high activity against gram-positive and gram-negative microbes, less active against proteus, staphylococcus, and helicobacter.

Flemoxin Solutabk contents ↑

Amoxicillin is available in tablets with a certain dosage and is most often used in adults because it can be destroyed by acid in the stomach. A feature of the Solutab dosage form is rapid absorption in the gastrointestinal tract and almost complete (more than 90%) absorption. The drug does not change the absorption of the active substance, even if taken with food. Its maximum concentration in the blood plasma is observed 1-2 hours after administration, and in this case it is much higher than when taking the insoluble form of this antibiotic.

Flemoxin Solutab tablets have a pleasant lemon-tangerine taste and should be taken without chewing before or after meals. This tablet can also be divided into several parts and chewed with water, or it can be dissolved in water and drunk. So, if you take 20 ml of water, you get a syrup, and if you take 100 ml of water, you get a suspension. The drug is mainly available in tablet form; the number on the tablet indicates the content of Amoxicillin.

Source: http://lor-prostuda.ru/otlichie-flemoksin-solyutab-ot-amoksic/

What is the difference between Flemoklav and Flemoxin

Timely prescription of medications and a well-designed drug therapy regimen are an important condition for the treatment of bacterial infections. Modern pharmacology offers a huge list of means to suppress the activity of pathogenic microflora. They all have different properties and characteristics. But today we decided to focus our attention on the drugs Flemoxin and Flemoklav. Is there a difference between these two drugs?

Composition of drugs

According to pharmaceutical data, Flemoxin is an analogue of Flemoklav. Many pharmacists offer it as an alternative to their customers if the prescribed medicine is out of stock. In fact, this is not entirely correct. And now we will explain why.

The active ingredient of one and the second drug is amoxicillin. It is an antibiotic of the penicillin series, known for its broad spectrum of action and effectiveness against a large number of pathogenic microorganisms. At the same time, Flemoclav also contains clavulanic acid, which not only protects antibiotic cells in the internal environment of the body, but also exhibits its own antibacterial activity, enhancing the effect of amoxicillin.

Here is the first difference - different pharmacological groups. Flemoxin is a penicillin antibiotic, and Flemoklav is a combination drug, penicillins with beta-lactamase inhibitors.

Release form and dosage

Flemoxin Solutab and Flemoklav Solutab are produced by Astellas Pharma Europe B.V. (Netherlands). Release form: dispersed tablets, easily soluble in water.

If for some reason the patient cannot take the medicine in solid tablet form, both products are suitable for preparing a pleasant-tasting suspension.

As for the dosage, some differences are already found here. Thus, Flemoxin is available in the following dosages:

Where mg is the amount of active ingredient amoxicillin in 1 tablet. Each tablet has an engraving corresponding to the dosage. For convenience, we have indicated it in parentheses.

The dosage for the drug Flemoklav indicates the amount of amoxicillin and clavulanic acid:

The tablets also have markings corresponding to the amount of active substance.

Pharmacological properties

Now let's move on to the question of what is the main difference between Flemoxin and Flemoclav. From a chemical point of view, amoxicillin is similar in structure to ampicillin. Both antibiotics have the same spectrum of action against pathogenic microorganisms. At the same time, amoxicillin is absorbed 50-60% better when taken orally. Thanks to this, a higher concentration of the active substance in the blood is achieved and, as a result, higher efficiency in the treatment of bacterial infections.

Amoxicillin, like other penicillin antibiotics, is called beta-lactam. The principle of operation of antibiotic molecules on the cells of pathogenic microorganisms is very simple. Due to its chemical structure, its structural components have the ability to bind to the center of the enzyme responsible for accelerating the production of peptidoglycan.

Peptidoglycan is an important component of the cell wall of pathogenic bacteria. Violation of the synthesis process of this important element interferes with the process of division of cellular structures.

The mechanism of development of bacterial inflammation is active cell proliferation, in which two daughter units are formed from each parent unit. Inhibition of the process of peptidoglycan production leads to a failure of the well-functioning mechanism and, as a consequence, the death of these cells.

But, unfortunately, not only humanity has evolved in our world, but also bacteria. Many of them have managed to develop a kind of protection against antibacterial drugs - beta-lactamase enzymes, which have the property of breaking down antibiotic molecules. This concept is better known to us as antibiotic resistance or resistance of pathogenic microflora to the action of a drug.

It is for such cases that combination drugs were developed, one of which is Flemoklav. Unlike Flemoxin, it contains clavulanic acid. When ingested, clavulanic acid molecules bind to bacterial enzymes and block their work. This allows you to preserve the integrity of the antibiotic cells and, as a result, achieve the maximum therapeutic effect.

Which drug to choose: effectiveness assessment

Considering the difference in pharmacological properties due to the composition of the drugs, their therapeutic effect will also differ. And where Flemoxin cannot effectively resist microorganisms that produce beta-lactamases, Flemoklav will cope with this task perfectly.

The main advantages of the combination antibiotic:

  • a wide range of applications due to the expansion of the list of bacteria sensitive to the action of the drug;
  • higher clinical effectiveness of the drug;
  • reducing the dose required to achieve a therapeutic effect.

Based on all of the above, we can draw the right conclusions that Flemoxin or Flemoklav is better. Thus, Flemoclav becomes the first choice drug for infectious diseases caused by bacteria that have already developed resistance to antibiotics. Among them:

  • otitis;
  • sinusitis;
  • bronchitis;
  • urinary tract infections;
  • skin and soft tissue infections;
  • abscesses of the oral cavity (including for the prevention of complications after surgery, tooth extraction).

Some facts in favor of Flemoclav indicate the following:

  1. Patients diagnosed with reactive arthritis (children). For a month, one group of patients was treated with amoxicillin, and the second was treated with a combination drug with clavulanic acid. The results of antibacterial therapy of the first group - 48% of children showed an improvement in their condition. The results of treatment with amoxicillin in combination with clavulanic acid were higher - 58% of young patients showed positive dynamics.
  2. Surgical dentistry. According to the observations of dentists, taking combined antibacterial agents can not only shorten the rehabilitation period after surgery (tooth extraction), but also significantly alleviate the patient’s condition.
  3. Complex treatment of gastric ulcer caused by Helicobacter pylori. Treatment with a combination antibiotic and clavulanate helps achieve complete recovery in 92% of cases. At the same time, a single dose of amoxicillin gives indicators not exceeding 85%.

Safety of Flemoxin and Flemoklav: is there a difference?

And after all this, a completely logical question arises: if combined antibiotics are so effective in fighting bacterial infections, then why produce single drugs at all? But, as we found out, Flemoxin differs from Flemoklav in its level of safety. Moreover, he is the leader in this category.

We all know about the side effects of taking amoxicillin. But clavulanic acid itself can cause unwanted reactions. Therefore, when taking combination drugs, the risks of developing these side effects significantly increase, and the list of contraindications expands.

According to statistics, when taking antibiotics in combination with clavulanic acid, complaints of gastric side effects are much more common. And the risk of developing liver disease increases sixfold!

Therefore, you should not self-medicate and choose medications at your own discretion. Without wanting to, you risk seriously undermining your health by not getting rid of the first problem - a bacterial infection.

Flemoxin and Flemoklav in pediatrics

Both drugs are used to treat bacterial infections in children. The daily dose of Flemoklav for children weighing up to 40 kg is calculated based on 30 mg of amoxicillin per kg of body weight. For Flemoxin, the formula is used to calculate mg of amoxicillin per kg of body weight.

More precise recommendations regarding the duration of the course and dosage regimen can be obtained from your doctor. When selecting a medicine, not only the type of infection will be taken into account, but also the age of the child, as well as the presence of concomitant diseases.

Cost of drugs

In conclusion, it is necessary to mention one more difference between these antibiotics - price. The standard treatment regimen for infection involves a weekly course provided that the drug is taken 2-3 times a day. Since the tablets are available in packs of 20, a full course will require 1 package of the drug. Prices for Flemoxin Solutab, depending on the dosage, fluctuate within rubles per package, for Flemoklav Solutab – rubles. That is, the difference is about 17-30%; the combined antibiotic with clavulanic acid is more expensive.

Antibiotics are not a harmless vitamin. Therefore, you cannot decide on your own which drug will be better in your case. Entrust this choice to a professional.

Source: http://pulmono.ru/lekarstva/dlya-legkih/raznitsa-mezhdu-flemoklavom-i-flemoksinom

What is the difference between Flemoklav and Flemoxin?

Often, with the beginning of the cold season, people need to take antibacterial drugs that suppress the activity of pathogens. The most common medications are considered to be the group of penicillins, prominent representatives of which are Flemoklav with Flemoxin. This article will help you understand the difference between Flemoxin and Flemoklav.

Indications for use

Both Flemoklav Solutab and Flemoxin Solutab have fairly high effectiveness against pathogens, against which Amoxicillin is effective.

These medications are effective in eliminating the following pathologies:

  • infectious pathologies of the respiratory system;
  • genitourinary system infections;
  • inflammatory processes of the skin;
  • diseases of bone tissue;
  • ENT diseases.

Flemoxin Solutab differs from Flemoklav Solutab in the absence of a broad composition, due to which Flemoklav has an increased ability to eliminate bacteria from the lactamase environment.

This is the best drug to combat the following microorganisms:

  • staphylococcus;
  • Pseudomonas aeruginosa;
  • hydrophilic aeromonas.

Important! Taking medications together is strictly prohibited.

In addition, Flemoklav is distinguished by its effectiveness in treating gastrointestinal diseases; it is effective against the Helicobacter bacterium. This advantage is achieved by the drug due to the presence of clavulanic acid, which does not allow pathogens to resist drug exposure. If a patient takes Flemoxin Solutab and it turns out that the disease is caused by the above representatives, then the drug should be replaced with another, stronger drug.

Active substance

Based on pharmaceutical data, Flemoxin is an analogue of the drug Flemoklav. Sometimes in the pharmacy, if the original has run out, they offer this particular substitute. In fact, this alternative is not always correct. The active ingredient of both drugs is amoxicillin. It belongs to the penicillin series, which has a fairly wide spectrum of action and is effective against a large number of pathogens.

However, Flemoklav has a wider composition. Along with amoxicillin, it contains clavulanic acid, known as a blocker of enzymes of the causative agent of the disease, which also has antibacterial activity. This intensity further expands the range of antimicrobial actions. Due to this, Flemoklav is able to block the enzymes of pathogenic bacteria that destroy amoxicillin.

Important! Clavulanic acid, which is part of Flemoklav, enhances the effect of amoxicillin.

When describing comparisons between Flemoxin and Flemoclav, it should be noted that they are similar in their active component. Based on this, the principle of influencing pathogenic microorganisms is approximately similar. However, Flemoklav is a combination drug, and Flemoxin is a single drug. This is the main difference between these medications.

Compound

Flemoklav and Flemoxin were released in the Netherlands. On the pharmaceutical market they are presented as dispersed tablets that easily dissolve in water. The tablets are in a blister of 4 pieces. in everyone. Moreover, 1 package can contain 4-8 blisters. These medications have different dosages. For example, Flemoxin is issued in the following dose, which is indicated in mg:

Moreover, the amount of mg. shows the content of the active ingredient in 1 tablet form. Each tablet is engraved with the exact amount of active ingredient indicated. The exact content of clavulanic acid is added to the dosage of amoxicillin in Flemoclav. The tablets are also labeled with the amount of active ingredients listed in mg.

Advice: when the patient cannot take the medicine in tablets, it can be prepared in the form of a suspension, which will have a rather pleasant taste.

When is Flemoklav prescribed?

Many people cannot decide which is better, between Flemoxin or Flemoklav, or how to make a choice in favor of one drug or another. First of all, the combination drug is prescribed when pathogenic bacteria have developed resistance to amoxicillin. This often happens when using Flemoxin Solutab on your own or stopping the drug too early. Most often this situation occurs with the following diseases:

In medicine, an experiment was carried out in which children were treated for reactive arthritis for 30 days with Flemoxin and Flemoclav. In the group taking Flemoxin, complete cure occurred in 48% of cases. Those who were treated with the combination drug were cured in 58%. The same results were observed in the treatment of gastric ulcers caused by the Helicobacter bacterium. Therapy with Flemoklav gave complete recovery in 92%, and with a single dose of amoxicillin, a positive result occurred in 85% of cases.

In addition, operative surgery notes that the combination of amoxicillin with clavulanic acid leads to a reduction in the period of complete recovery. Typically, during recovery, patients taking this drug experience faster relief from swelling and less pain than those treated with Flemoxin.

Advantages of Flemoclav

Having considered the effect of both drugs, we can say that you can take both drugs if you have an infectious disease. Flemoxin can successfully cope with a number of pathogenic microorganisms. If the causative agent of the disease is not known in the patient, then it would be good to opt for Flemoklav. Since it gives a better chance of a speedy recovery due to the presence of clavulanic acid. Its introduction gives the combination drug the following advantages:

  • Expanded number of drug-sensitive microorganisms;
  • Reduced antibiotic dosage;
  • Increased effectiveness of the product.

Side effects

Mentioning the difference between Flemoxin and Flemoclav, it should be said that the single drug is safer to use. Everyone knows about adverse reactions of antibiotics. However, clavulanic acid, which is part of the combined product, also has a number of side effects. It turns out that while taking Flemoclav, a number of undesirable effects increase significantly and, accordingly, the number of contraindications increases.

Based on reviews of people who have taken this drug, it can be argued that the combination of clavulanic acid with an antibiotic increases complaints from the gastrointestinal tract several times. When taken regularly, the risk of liver pathologies increases 6 times.

Treatment of children

Both of these drugs can be prescribed in pediatrics for the treatment of bacterial infections. Moreover, the instructions say that they can be given to a child from 3 months of age. There is a difference in dosage between Flemoxin and Flemoklav for the treatment of children. When treating with the first drug, the calculation is made using the following formula: per 1 kg. The child’s weight is taken from 40 to 60 mg. amoxicillin. In severe cases of the disease, a large dosage of antibiotic is prescribed.

The daily dosage of Flemoclav should not exceed mg. per 1 kg. child's weight. A more precise recommendation for admission is given by the attending physician, based on the condition of the baby and his individual characteristics. When selecting a drug and its quantity, the child’s weight, type of pathogen, and the presence of chronic diseases are taken into account.

Cost of medicines

In addition, you should indicate the difference in price between Flemoxin and Flemoklav. Doctors usually prescribe treating the infection for a week, taking an antibiotic twice or three times a day. Since a standard package usually contains 20 tablets, you will need to purchase one package to complete the full course.

The cost of Flemoxin Solutab in pharmacies varies from 230 to 470 rubles. This difference in price depends on the dosage of the drug. Flemoklav Solutab can be purchased in exchange. per package. It follows from this that a combination antibiotic usually costs 20% more than a single drug.

Flemoxin and Flemoklav are quite serious drugs, treatment of which should be started only after a doctor’s prescription.

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IMPORTANT. The information on the site is provided for informational purposes only. Do not self-medicate. At the first sign of disease, consult a doctor.

Source: http://pillsman.org/24566-flemoksin-i-flemoklav.html