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Flamin

Flamin is a drug created on the basis of natural plant raw materials (sandy immortelle extract), and due to the natural bioflavonoids it contains, it has a pronounced cholekinetic (choleretic), choleretic and antispasmodic effect.

Table of contents:

The drug is usually used as a choleretic agent for chronic hepatocholecystitis (simultaneous inflammation of the bile ducts and liver tissue) and cholecystitis.

In this article we will look at why doctors prescribe Flamin, including instructions for use, analogues and prices for this drug in pharmacies. Real REVIEWS of people who have already used Flamin can be read in the comments.

Composition and release form

Flamin is available in the form of tablets of 50 mg, packaged in pieces or granules, in glass jars of 250 ml.

  • The preparation contains an active component: the sum of flavonoids from the flowers of the sandy immortelle.
  • Additional ingredients: pectin, citric acid, sorbic acid, sugar.

Pharmacological action: has choleretic, cholekinetic, choleretic, anti-inflammatory, antibacterial, antispasmodic and wound-healing effects.

Indications for use

According to the official instructions for use of Flamin, the therapeutic and prophylactic effect of this drug is noted in relation to the following pathologies:

  • hepatitis;
  • cholangitis;
  • hepatocholecystitis;
  • obesity;
  • biliary dyskinesia;
  • diabetes;
  • eye burns;
  • chronic cholecystitis;
  • giardiasis;
  • postcholecystectomy syndrome.

pharmachologic effect

Herbal product; has choleretic, cholekinetic, choleretic, anti-inflammatory, antibacterial, antispasmodic and wound-healing effects. Enhances the secretion of bile and increases the content of bilirubin in it, increases the tone of the gallbladder and promotes the outflow of bile. It has a relaxing effect on the smooth muscles of the sphincters of the gallbladder and bile ducts, changes the viscosity and chemical composition of bile.

Flamin has a positive effect on the pancreas, activating its exocrine activity. Flamin acts as an antibacterial drug against gram-positive bacteria and helps to increase the therapeutic activity of metronidazole and aminoquinol in the treatment of giardiasis. According to reviews of Flamin, the drug enhances the regenerative functions of eye tissue.

Instructions for use

For adults, the instructions for use recommend taking Flamin tablets 50 mg 3 times daily, before meals, with water. The duration of therapy may be days.

  • When treating children, the drug is used in granules. This form is intended for preparing a suspension. To prepare it, you need to mix the contents of the bottle with cool boiled water and shake thoroughly.
The dosage of the suspension depends on the age of young patients. For example, children from a month to a year can be given 2.5 ml at a time, up to 7.5 ml per day. For children 1-3 years old, a single dosage is established - 5 ml and 15 ml - daily, 4-5 years old - 7.5 ml - at one time, 22.5 ml - per day, from 5 years old, 10 ml per single dose, 30 ml – per day.

The average duration of therapy is days. If necessary, the course of treatment is increased.

Contraindications

The instructions contain contraindications for the use of Flamin for:

  • obstruction of the bile ducts;
  • gastric ulcer in the acute stage;
  • obstructive jaundice;
  • individual intolerance to the components of the drug;
  • severe liver failure;
  • children under 5 years of age (tablets);
  • inflammatory diseases of the liver and biliary tract in the acute stage.

Side effects

According to reviews of Flamin, in most cases the drug is well tolerated by the body, however, in a number of clinical situations, side effects may occur. Among them are allergic reactions, expressed by rash, redness of the skin, swelling, as well as increased blood pressure (when Flamin is used by patients suffering from arterial hypertension). Cases of overdose of the herbal medicine have not been recorded.

Analogs

The drug Flamin has no structural analogues of the active substance.

Allohol, Hofitol, Glutargin and Holiver also have a similar effect.

The average price of FLAMIN, tablets in pharmacies (Moscow) is 160 rubles.

Terms of sale

The drug can be purchased without a prescription.

For 2 days my side hurt, as if being pricked with a needle. I still endured the first day, but on the second it became clear that the pain was not just like that and I went to our clinic. The doctor listened to me and sent me for ultrasound diagnostics. When they looked at me and said that the bile ducts were inflamed, I was generally in shock. I had never encountered anything like this and had no idea what it was or how to treat it.

Choleretic is just super. They gave it to the little one when he had constipation. Just if you are planning to buy, don’t get confused. For adults there are tablets, and for children there are bags of granules. They need to be diluted in water and given 2 or 3 times a day, depending on the problem.

Source: http://instrukciya-po-primeneniyu.com/flamin/

Flamin tablets and granules (for children) – instructions for use, analogues, reviews, price

Flamin - composition and release forms

1. Tablets for oral administration;

2. Granules for the preparation of a suspension for oral administration (for children).

The tablets contain 50 mg of immortelle extract and are available in packs of 10 and 30 pieces. Flamin granules are packaged in sachets containing a single dosage of the drug for children. Each packet of granules contains 5 mg of immortelle extract. Some instructions indicate the dosage of granules as 1.38 g. However, this figure reflects the total weight of the granules in the bag, and not the amount of the active component. Thus, the dosage of the active component in Flamin tablets is 10 times greater than in granules.

Flamin – photo

This photo shows the packaging of Flamin for children in the form of granules for the preparation of a solution for oral administration.

This photo shows the packaging of Flamin for adults in the form of tablets for oral administration.

Therapeutic effect

Indications for use

  • Biliary dyskinesia;
  • Chronic cholecystitis;
  • Chronic cholecystohepatitis;
  • Cholelithiasis.

Based on the results of recent studies, it was found that Flamin is advisable to use in the complex therapy of atopic dermatitis combined with pathology of the gastrointestinal tract.

Flamin - instructions for use

Granules (sachets, powder, suspension) Flamin

  • Children aged 1 month – 1 year – give 1 sachet per day;
  • Children aged 1 – 3 years – give 2 sachets per day;
  • Children aged 4 – 5 years – give 3 sachets per day;
  • Children over 5 years old - give 4 sachets per day.

The indicated daily dosages of Flamin for children are divided into 3 doses and given to the child before breakfast, lunch and dinner. It is most convenient to divide the daily dosage into single dosages as follows: in the morning, dilute the required number of granule bags according to the child’s age, and then calculate the total volume of the resulting suspension. For example, if a child needs two sachets of Flamin per day, then the total daily volume of the finished suspension is 7.5 * 2 = 15 ml. After this, the total daily volume of the suspension is divided by 3 and a single dosage of Flamin is obtained, which must be given to the child three times a day. In our example, the single dosage of the suspension is 15 ml/3 = 5 ml. That is, the child needs to be given 5 ml of suspension 3 times a day. To measure the required amount of the finished suspension, it is optimal to use the measuring spoon included with the package.

Flamin tablets

  • Children aged 5 – 10 years – it is recommended to take one tablet once a day;
  • Children aged 10 – 14 years – it is recommended to take one tablet twice a day.

The duration of treatment with Flamin tablets in children and adults is the same and ranges from 10 to 40 days. If necessary, courses of therapy can be repeated, maintaining an interval of at least 5 days between them.

Overdose

Impact on the ability to operate machinery

Interaction with other drugs

Flamin for children

General provisions

Flamin for children - instructions for use

  • Children aged 1 month - 1 year - give 2.5 ml of suspension three times a day (7.5 ml per day);
  • Children aged 1 – 3 years – give 5 ml of suspension three times a day (15 ml per day);
  • Children aged 4 - 5 years - give 7.5 ml of suspension three times a day (22.5 ml per day);
  • Children 5 - 10 years old - give 10 ml of suspension three times a day (30 ml per day) or one tablet once a day;
  • Children 10 – 14 years old – it is recommended to take one tablet twice a day;
  • Adolescents over 14 years of age - take one tablet three times a day.

The suspension must be prepared from Flamin granules. To do this, dilute 1 bag of granules with 7.5 ml of water. If you take 2 bags of granules, then add 15 ml of water, etc. The prepared suspension is stored at room temperature for a maximum of 10 days. After 10 days, the remainder of the unused suspension is discarded, and if it is necessary to continue treatment, a new portion is diluted. To prepare the suspension, use only freshly boiled and cooled water.

Use during pregnancy and breastfeeding

Flamin for constipation

  • Children aged 1 month - 1 year - 2.5 ml of suspension three times a day (7.5 ml per day);
  • Children aged 1 – 3 years – 5 ml of suspension three times a day (15 ml per day);
  • Children aged 4 – 5 years – 7.5 ml of suspension three times a day (22.5 ml per day);
  • Children 5 – 10 years old – 10 ml of suspension three times a day (30 ml per day) or one tablet once a day;
  • Children 10 – 14 years old – one tablet twice a day;
  • Adolescents over 14 years of age and adults – one tablet three times a day.

Such courses of therapy can be repeated periodically, maintaining intervals of at least 5 days between them.

Side effects

Contraindications for use

  • Individual hypersensitivity or allergic reactions to Flamin components;
  • Obstruction of the bile ducts;
  • Obstructive jaundice;
  • Period of exacerbation of gastric ulcer;
  • Acute phase of inflammatory diseases of the liver and biliary tract;
  • Severe liver failure;
  • Ages under 5 years (tablets only).

Flamin - analogues

  • Allochol tablets;
  • Arnica tincture;
  • Artichol tablets;
  • Artichoke extract, pills and tablets;
  • Barberry leaves tincture;
  • Berberine tablets;
  • Hepabel tablets;
  • Hepatofite herbal collection and brewing bags;
  • Hepaphytol tablets;
  • Hepabene capsules;
  • Choleretic fees No. 1, No. 2 and No. 3;
  • Cavechol granules for the preparation of solution for oral administration;
  • Convaflavin tablets;
  • Corn silk extract and herb;
  • Leptandra compositum drops;
  • Lyobil tablets;
  • Odeston tablets;
  • Oxafenamide tablets;
  • Olimethine capsules;
  • Dried tansy flowers;
  • Piflamin tablets;
  • Polyphytol tincture;
  • Rafacholine tablets;
  • Tanacechol tablets;
  • Febichol capsules;
  • Phytohepatol No. 1, No. 2 and No. 3 herbal collection;
  • Flamin granules for the preparation of suspensions and tablets;
  • Holagogum capsules;
  • Cholagol drops for oral administration;
  • Holebil capsules;
  • Hole-gran granules;
  • Choledius drops;
  • Cholemax syrup;
  • Cholenzym tablets;
  • Holiver tablets;
  • Choline chloride solution for injection;
  • Cold syrup;
  • Kholosas syrup;
  • Hofitol tablets, solution for injection and for oral administration;
  • Cyclalone tablets;
  • Cinarix tablets;
  • Cinacholine syrup.

Reviews

Flamin for children - reviews

Flamin or Hofitol?

Drug price

  • Tablets 50 mg, 30 pieces – 247 – 310 rubles;
  • Granules 5 mg, 20 sachets – 215 – 294 rubles.

The drug is dispensed from pharmacies without a doctor's prescription. When purchasing, you must pay attention to the expiration date, which is 5 years from the date of manufacture. Flamin should be stored in a dark and dry place at an air temperature of 8 – 25 o C.

Author: Nasedkina A.K. Specialist in research of biomedical problems.

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Source: http://www.tiensmed.ru/news/flamin-ab1.html

Fluimucil - instructions for use, analogs, reviews and release forms (granules 200 mg, powder, solution for inhalation antibiotic IT in ampoules, effervescent tablets 600 mg) of a drug for the treatment of cough in adults, children and pregnancy

In this article you can read the instructions for use of the drug Fluimucil. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Fluimucil in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Fluimucil in the presence of existing structural analogues. Use for the treatment of cough and thinning of sputum in adults, children, as well as during pregnancy and breastfeeding.

Fluimucil is a mucolytic drug. Liquefies mucus, increases its volume and facilitates its separation. The effect of acetylcysteine ​​(the active ingredient of the drug Fluimucil) is associated with the ability of its sulfhydryl groups to break intra- and intermolecular disulfide bonds of acidic mucopolysaccharides of sputum, which leads to depolarization of mucoproteins and a decrease in sputum viscosity. Remains active in the presence of purulent sputum.

Increases the secretion of less viscous sialomucins by goblet cells, reduces the adhesion of bacteria to the epithelial cells of the bronchial mucosa. Stimulates mucous cells of the bronchi, the secretion of which is lysed by fibrin. It has a similar effect on the secretions formed during inflammatory diseases of the ENT organs.

It has an antioxidant effect due to the presence of an SH group that can neutralize electrophilic oxidative toxins.

Acetylcysteine ​​easily penetrates into the cell and is deacetylated to L-cysteine, from which intracellular glutathione is synthesized. Glutathione is a highly reactive tripeptide, a powerful antioxidant and cytoprotector that neutralizes endogenous and exogenous free radicals and toxins. Acetylcysteine ​​prevents exhaustion and helps increase the synthesis of intracellular glutathione, which is involved in the redox processes of cells, promoting the detoxification of harmful substances. This explains the effect of acetylcysteine ​​as an antidote for paracetamol poisoning.

Protects alpha1-antitrypsin (elastase inhibitor) from the inactivating effects of HOCl, an oxidizing agent produced by myeloperoxidase of active phagocytes. It also has an anti-inflammatory effect (by suppressing the formation of free radicals and reactive oxygen-containing substances responsible for the development of inflammation in the lung tissue).

Acetylcysteine ​​+ excipients.

Thiamphenicol glycinate acetylcysteinate + excipients (Fluimucil antibiotic IT).

When taken orally, it is well absorbed from the gastrointestinal tract. Penetrates into the intercellular space, predominantly distributed in the liver, kidneys, lungs, and bronchial secretions. Penetrates through the placental barrier. Rapidly deacetylated to cysteine ​​in the liver. In the plasma, a mobile equilibrium of free acetylcysteine ​​and its metabolites (cysteine, cystine, diacetylcystine) is observed, free and bound to plasma proteins. It is excreted in the urine in the form of inactive metabolites (inorganic sulfates, diacetylcysteine), a small part is excreted unchanged through the intestines.

  • respiratory diseases accompanied by impaired sputum discharge (including bronchitis, tracheitis, bronchiolitis, pneumonia, bronchiectasis, cystic fibrosis, lung abscess, pulmonary emphysema, laryngotracheitis, interstitial lung diseases, pulmonary atelectasis (due to blockage of the bronchi by mucus plug));
  • catarrhal and purulent otitis, sinusitis, incl. sinusitis (to facilitate the passage of secretions);
  • to remove viscous secretions from the respiratory tract in post-traumatic and postoperative conditions;
  • preparation for bronchoscopy, bronchography, aspiration drainage;
  • for washing abscesses, nasal passages, maxillary sinuses, middle ear, treatment of fistulas, surgical field during operations on the nasal cavity and mastoid process;
  • with concomitant nonspecific forms of respiratory infections to improve drainage, including cavernous lesions, with mycobacterial infections.

Solution for injection and inhalation (sometimes mistakenly called syrup).

Effervescent tablets 600 mg.

Granules for the preparation of a solution for oral administration 200 mg (sometimes mistakenly called powder).

Lyophilisate for the preparation of solution for injection and inhalation in ampoules (Fluimucil antibiotic IT).

Instructions for use and method of use

For aerosol therapy, 3-9 ml of a 10% solution is sprayed in ultrasound devices, and 6 ml of a 10% solution is sprayed in devices with a distribution valve. Duration of inhalation min; frequency: once a day. When treating acute conditions, the average duration of therapy is days; for long-term therapy of chronic conditions, the course of treatment is up to 6 months.

Due to the high safety of the drug, the frequency of administration and the relative dose can be changed by the doctor within acceptable limits, depending on the patient’s condition and the therapeutic effect. There is no need to change the adult dose when using the drug to treat children. In the case of a strong secretolytic effect, the secretion is sucked out, and the frequency of inhalations and the daily dose are reduced.

The therapeutic mixture cannot be placed in an ultrasonic nebulizer, because it quickly destroys the active substance Fluimucil. It is advisable to use a compressor device for inhalation, which provides an ideal setting for the size of the inhaled particles of the drug.

To wash the bronchial tree during therapeutic bronchoscopy, use 1-2 ampoules or more per day, depending on clinical indications.

Instill in the external auditory canal and nasal passages (in the nose) mg (1.5-3 ml) for 1 procedure.

Administer intravenously (preferably drip or slow stream over 5 minutes) or intramuscularly. Adults - 300 mg (3 ml) 1-2 times a day; children from 6 to 14 years old - 150 mg (1.5 ml) 1-2 times a day. The daily dose for children under 6 years of age is 10 mg/kg body weight; for children under 1 year of age, intravenous administration of acetylcysteine ​​is possible only for health reasons in a hospital setting. The duration of treatment should be determined based on changes in the patient's condition.

It should be taken into account that oral administration of the drug is preferable for children under 6 years of age.

High local and general tolerability of the drug allows for long courses of treatment.

For intravenous administration, the solution is further diluted with 0.9% sodium chloride solution or 5% dextrose solution in a 1:1 ratio. The duration of therapy is determined individually (no more than 10 days).

In patients over 65 years of age, the minimum effective dose is used.

The drug in the form of effervescent tablets is prescribed to adults at 600 mg (1 tablet) 1 time per day. Before use, the effervescent tablet is dissolved in 1/3 glass of water.

Granules for preparing a solution for oral administration are prescribed to adults and children over 6 years old - 200 mg 2-3 times a day; children aged 2 to 6 years - 200 mg 2 times a day or 100 mg 3 times a day; children aged 1 to 2 years - 100 mg 2 times a day.

In newborns, the drug is used only for health reasons at a dose of 10 mg/kg body weight under the strict supervision of a physician.

Before use, the required amount of granules is dissolved in 1/3 glass of water. Children of the first year of life are given the resulting solution to drink from a spoon or feeding bottle.

The duration of the course of treatment is determined individually. For acute diseases, the duration of treatment is from 5 to 10 days, for chronic diseases - up to several months.

  • reflex cough;
  • respiratory tract irritation;
  • rhinorrhea;
  • stomatitis;
  • bronchospasm;
  • burning at the injection site;
  • skin rash;
  • hives;
  • impaired liver and/or kidney function (with long-term use).
  • peptic ulcer of the stomach and duodenum in the acute phase;
  • lactation period;
  • children under 2 years of age (for granules for the preparation of a solution for oral administration);
  • children and adolescents up to 18 years of age (for effervescent tablets);
  • anemia;
  • leukopenia;
  • thrombocytopenia;
  • hypersensitivity to acetylcysteine.

Use during pregnancy and breastfeeding

During pregnancy, the use of Fluimucil is possible only if the expected benefit to the mother outweighs the potential risk to the fetus.

If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped.

For patients with bronchial asthma and obstructive bronchitis, acetylcysteine ​​should be prescribed with caution under systematic monitoring of bronchial patency.

With shallow intramuscular injection of the drug and in the presence of increased sensitivity, a slight and quickly passing burning sensation may appear, and therefore it is recommended to inject the drug deep into the muscle.

The Fluimucil ampoule is opened before use. An opened ampoule can be stored in the refrigerator for 24 hours, during which time the drug can only be used for inhalation.

Fluimucil solution should not come into contact with rubber and metal surfaces.

Prescribed with caution for peptic ulcers of the stomach and duodenum in remission, varicose veins of the esophagus, hemoptysis, pulmonary hemorrhage, bronchial asthma (with intravenous administration the risk of developing bronchospasm increases), diseases of the adrenal glands, liver and/or kidney failure, arterial hypertension, and also for children under 6 years of age.

For children under 1 year of age, intravenous administration of acetylcysteine ​​is possible only for health reasons in a hospital setting.

The simultaneous use of Fluimucil with antitussives may increase sputum stagnation due to suppression of the cough reflex.

When used simultaneously with antibiotics, such as tetracyclines (excluding doxycycline), ampicillin, amphotericin B, they may interact with the thiol group of acetylcysteine, which leads to a decrease in the activity of both drugs, so the interval between taking acetylcysteine ​​and antibiotics should be at least 2 hours.

The simultaneous use of Fluimucil and nitroglycerin can lead to an increase in the vasodilatory effect of the latter.

Acetylcysteine ​​reduces the hepatotoxic effect of paracetamol.

Pharmaceutically incompatible with other drug solutions.

Analogues of the drug Fluimucil

Structural analogues of the active substance:

  • N-AC-ratiopharm;
  • N-acetylcysteine;
  • Acestine;
  • Acetylcysteine;
  • Acetylcysteine ​​solution for inhalation 20%;
  • Acetylcysteine ​​solution for injection 10%;
  • ACC;
  • ACC 100;
  • ACC 200;
  • ACC injection;
  • ACC Long;
  • Vicks Active ExpectoMed;
  • Mukobene;
  • Mucomist;
  • Mukonex;
  • Fluimucil;
  • Exomyuk 200.

Similar medications:

Other medicines:

News edited by: admin017, 12:37

Source: http://instrukciya-otzyvy.ru/571-fluimucil-po-primeneniyu-analogi-granuly-poroshok-rastvor-ingalyaciya-antibiotik-it-tabletka.html

Flamin

Instructions for use:

Prices in online pharmacies:

Flamin is a herbal product. The active ingredient of the herbal medicine is immortelle flowers, which provide the choleretic properties of the medicine.

The dosage forms of Flamin according to the instructions are eye ointment, granules for preparing a suspension, powder for preparing a suspension, herbal raw materials, crushed herbal raw materials, briquettes with herbal raw materials and tablets.

Pharmacological action of Flamin

Flamin has pronounced choleretic, choleretic, cholekinetic, antibacterial, anti-inflammatory, wound-healing, and antispasmodic effects. The use of Flamin helps to increase the tone of the gallbladder and the outflow of bile, increase the content of bilirubin in bile, remove cholesterol along with bile, and also dissolve stones accumulated in the gallbladder. The active components of Flamin stimulate the secretion of gastric juice, helping to better digest food and helping to slow down the evacuation function of the intestines and stomach.

Flamin successfully activates the exocrine activity of the pancreas. The drug has an antibacterial effect against gram-positive bacteria, increases the therapeutic activity of aminoquinol and metronidazole in the treatment of giardiasis. According to reviews of Flamin, the drug increases the regenerative functions of eye tissue.

Indications for use of Flamin

The drug has therapeutic and preventive activity against diseases such as hepatitis, hepatocholecystitis, chronic cholecystitis, biliary dyskinesia, postcholecystectomy syndrome, cholangitis. Flamin is widely used as part of combination therapy for obesity, giardiasis, diabetes mellitus, acting as one of the components of complex treatment.

Contraindications

Contraindications for Flamin according to the instructions for use of the drug include hypersensitivity to the components of the product. It is not recommended to take Flamin for gastric ulcers, jaundice caused by blockage of the bile ducts, as well as in children under 5 years of age.

Side effects

According to reviews of Flamin, in most cases the drug is well tolerated by the body, however, in a number of clinical situations, side effects may occur. Among them are allergic reactions, expressed by rash, redness of the skin, swelling, as well as increased blood pressure (when Flamin is used by patients suffering from arterial hypertension). Cases of overdose of the herbal medicine have not been recorded.

Directions for use of Flamin and dosage

Flamin is administered orally in the form of tablets, 0.05 g 3 times a day, half an hour before meals, the duration of treatment is days.

In powder form, it is advisable to take the drug 1 g 3 times a day for 2-3 weeks.

Granules for suspension are taken orally 30 minutes before meals 3 times a day. To prepare it, add boiled water cooled to room temperature to the contents of the jar up to the 100 ml mark and shake the granules until they are completely dissolved.

Flamin is taken in the form of a decoction 3-4 times a day 15 minutes before meals. Preparation of the decoction: 10 g of the mixture is poured into 200 ml of water and heated in a water (boiling) bath, stirring frequently. Then the resulting decoction is filtered, diluted with water to the original volume and taken orally according to the instructions.

Flamina eye ointment is applied to the lower eyelid for 6-8 days, 3-4 times a day.

These instructions for Flamin are not intended for use without first consulting a doctor.

Flamin tablets 50 mg 30 pcs.

Flamin tablets 50 mg 30 pcs.

Flamin 50mg No. 30 tablets

Flamin tab. 50mg n30

Flamin 50 mg n30 tablet

Flamin 50mg No. 30 tablet

Flamin for children 1.38g granulate No. 20 pack.

Information about the drug is generalized, provided for informational purposes and does not replace official instructions. Self-medication is dangerous to health!

A person taking antidepressants will, in most cases, become depressed again. If a person has coped with depression on his own, he has every chance to forget about this condition forever.

Research shows that women who drink several glasses of beer or wine per week have an increased risk of developing breast cancer.

In an effort to get the patient out, doctors often go too far. For example, a certain Charles Jensen in the period from 1954 to 1994. survived more than 900 operations to remove tumors.

When lovers kiss, each of them loses 6.4 calories per minute, but at the same time they exchange almost 300 types of different bacteria.

It was previously believed that yawning enriches the body with oxygen. However, this opinion has been refuted. Scientists have proven that yawning cools the brain and improves its performance.

Human blood “runs” through the vessels under enormous pressure and, if their integrity is violated, it can shoot at a distance of up to 10 meters.

Tooth decay is the most common infectious disease in the world, which even the flu cannot compete with.

Besides people, only one living creature on planet Earth suffers from prostatitis - dogs. These are truly our most faithful friends.

If your liver stopped working, death would occur within 24 hours.

An educated person is less susceptible to brain diseases. Intellectual activity promotes the formation of additional tissue that compensates for the disease.

The well-known drug Viagra was originally developed for the treatment of arterial hypertension.

The average life expectancy of left-handers is shorter than that of right-handers.

Human bones are four times stronger than concrete.

Millions of bacteria are born, live and die in our intestines. They can only be seen under high magnification, but if they were put together, they would fit in a regular coffee cup.

According to statistics, on Mondays the risk of back injuries increases by 25%, and the risk of a heart attack by 33%. Be careful.

The German healthcare system is considered one of the best in Europe and throughout the world. Oncologists in Germany have achieved particular success. After therapy in clinics of the countries.

Source: http://www.neboleem.net/flamin.php

Antibiotic "Fluimucil" - instructions for use and reviews

A universal combined drug that has an antimicrobial effect and thins sputum is the antibiotic Fluimucil. It is produced in bottles that come complete with a solvent – ​​water, intended for injection.

Description of the drug

The main active ingredient of the drug is thiamphenicol glycinate acetylcysteinate. The product “Fluimucil-antibiotic IT” looks like a white powder. It is packaged in bottles of 250 or 500 mg. Also included in the package is water for injection, 2 or 4 mg in each ampoule, depending on the dosage.

This drug is a combination product that simultaneously contains the antibiotic thiamphenicol in combination with the mucolytic acetylcysteine. The antibacterial effect is achieved due to the fact that the active substance is active against many bacteria, especially those that cause problems with the respiratory tract. Thus, it is prescribed in cases where the causative agents are gram-positive microorganisms such as Staphylococcus spp., Streptococcus pneumoniae, Listeria spp., Streptococcus pyogenes, Corynebacterium diphtheria, Str. faecalis, Clostridium spp. It also helps cope with the following gram-negative bacteria: Neisseria, Haemophilus influenza, Escherichia coli, Salmonella, Shigella spp., Brucella spp., Bordetella pert., Bacteroides spp, Yersinia pestis.

Mechanism of action

The high effectiveness of this broad-spectrum antibacterial agent is achieved due to the fact that thiamphenicol inhibits the synthesis of microbial cell walls. And acetylcysteine, in turn, breaks the bonds of mucoproteins. Thanks to this, the antibiotic “Fluimucil” helps liquefy sputum quickly and effectively, regardless of whether it was purulent or mucous. Moreover, the mucolytic helps thiamphenicol penetrate tissue more easily and destroy bacterial cells directly in the respiratory tract, which speeds up recovery.

The maximum concentration of the antibiotic is observed 15 minutes after it was administered intramuscularly. It accumulates directly in the tissues of the respiratory tract. The drug "Fluimucil-antibiotic IT" is metabolized in the liver and excreted in the urine and in small quantities in feces.

Indications

It is necessary to use any antibacterial agents only after the appointment of a specialist. The drug “Fluimucil” (antibiotic) is no exception. Instructions for use contain information about when it can be prescribed. But patients should read it for informational purposes only, and not try to engage in therapy on their own.

It is prescribed to treat many respiratory diseases. But do not forget that it will be effective only in cases where the disease is caused by bacteria that are sensitive to thiamphenicol, and is accompanied by difficulties with sputum discharge.

Scope of use

The antibiotic "Fluimucil" can be prescribed for the following otolaryngological problems: laryngotracheitis, sinusitis, catarrhal otitis, infectious and obstructive complications of tracheostomy. It is also used in preparation for bronchoscopy.

It is often prescribed for the treatment of bronchitis, long-term pneumonia, and lung abscess. Bronchiectasis, emphysema and cystic fibrosis are also diseases for which the drug “Fluimucil-antibiotic IT” is recommended. Reviews indicate that the results of treatment appear almost the next day. The condition improves significantly after just 3-4 days. By the way, it can also be prescribed to children.

This drug is also used in surgery. The need for it arises after a series of thoracic surgical interventions, which may result in bronchopneumonia or atelectasis.

Phthisiatricians can use it in cases where pulmonary tuberculosis is accompanied by nonspecific forms of bronchial catarrh, with delayed discharge resulting from insufficient drainage.

Method of use

Many people mistakenly believe that there is only one way to use Fluimucil (an antibiotic). The instructions for use offer several options. In addition to intramuscular administration, its solution is used for inhalation, rinsing cavities, and even for application to problem areas.

If we are talking about injections, then for adults and adolescents over 12 years of age it is prescribed in a dosage of 500 mg and can be administered intramuscularly up to 3 times a day. Children over 7 years old are recommended to take 250 mg three times, and from 3 to 7 years old - in the same dosage, only 2 times a day. Children under 2 years of age are given injections of 125 mg twice a day.

If the doctor recommended the drug “Fluimucil-antibiotic IT” for inhalation, then it is important to understand that a single dose for adults cannot exceed 250 mg. And for children, 125 mg will be enough. You can do such inhalations 1 or 2 times a day.

It can also be infused intratracheobronchially through an installed permanent probe or during bronchoscopy. They can be used to wash the sinuses, treat the eardrum and other areas during surgical interventions. Sometimes doctors recommend dripping it into the nose or ears.

For rinsing, use 500 mg of the drug for adults and 250 for children. For instillation into the ears and nose, 2-4 drops of the prepared solution are enough.

A course of treatment

Like most antibacterial agents, this drug is prescribed for at least 5 days. But, as a rule, therapy should last from 7 to 10 days. Only in this case can the bacteria that cause the disease be destroyed. As prescribed by a doctor, if the need is confirmed, the course can be extended. But at the same time it is recommended to monitor the composition of the blood. It will be necessary to interrupt treatment if the number of leukocytes drops to a level of less than 4 thousand per cm 3, and the number of granulocytes decreases by more than 40%.

If necessary, the doctor can double the dosage of the drug intended for intramuscular administration. This is not recommended only in cases where newborns, premature babies and people over 65 years of age are treated using Fluimucil (an antibiotic). Feedback from patients suggests that doctors rarely resort to such excess dosages.

Contraindications

Despite the fact that this broad-spectrum antibiotic can be administered even to children who are not yet two years old, it is not prescribed to everyone. It cannot be used for leukopenia and anemia. If the patient has a history of thrombocytopenia, then it is also contraindicated.

Hypersensitivity to components, lactation and pregnancy are also included in the list of situations when it is better not to use this drug. Severe disturbances in the functioning of the kidneys or liver also impose restrictions.

Side effects

In rare cases, the use of an antibacterial agent may cause complications. Side effects include possible bronchospasm and allergic reactions. In cases where intramuscular administration is prescribed, disturbances in hematopoietic functions are also possible. Anemia and reticulocytopenia may develop. Diseases such as thrombocytopenia and leukopenia occur very rarely.

If you use the drug "Fluimucil" (antibiotic) for inhalation, the instructions warn that problems may also arise. Stomatitis or rhinitis may develop as a side effect. Some note that nausea occurs after inhalation.

Patient reviews

Many people note that the effect of using an antibiotic becomes noticeable literally the next day. It has an antimicrobial effect, thins mucus and promotes its removal. Fluimucil (an antibiotic) is often used for inhalation. Reviews confirm that to improve the condition it is not necessary to use only intramuscular administration. Inhalations with this drug can eliminate an obsessive cough and make it productive. The most optimal effect is achieved when using a nebulizer. This device ensures that particles of the product enter directly into the respiratory tract.

But you shouldn’t prescribe it yourself, without consulting a specialist. Only a doctor can determine whether you need to take an antibacterial agent in your case. The doctor must also choose the method of its use.

Preparation of the solution

If you have been prescribed intramuscular administration of the drug, then the water for injection included in the kit will be useful. It is used to dissolve dry powder. It is necessary to use 1 ampoule of water for each bottle. If you have been prescribed a one-time injection of not 500 mg, but a smaller amount, then you should not think that you need to look for another way to dilute Fluimucil. The antibiotic, prepared in the form of a solution, can be easily divided. If you need 250 mg, then simply put half of the total amount into the syringe, and to get 125 mg - ¼ part.

If you need to inhale, you can store the diluted powder in the refrigerator. By the way, for this purpose it can be dissolved not in water for injection, but in saline solution.

Interaction with other drugs

If you have been prescribed the antibiotic Fluimucil, you should consult your doctor before taking other medications. For example, the use of antitussives simultaneously with this drug can cause sputum stagnation due to the fact that the cough reflex will be blocked.

It is also important to know that acetylcysten reduces the hepatotoxic effect of drugs that contain paracetamol. And the simultaneous use of the drug “Fluimucil” with antibiotics such as “Ampicillin”, “Tetracycline”, “Amphotericin” causes the active effect of both drugs to decrease. Therefore, there should be an interval of at least 2 hours between their use.

The combination of the antibiotic "Fluimucil" and the drug "Nitroglycerin" leads to an increase in the antiplatelet and vasodilatory effects of the latter.

Shelf life and storage conditions

The drug in closed bottles at a temperature not exceeding 25 o C can be stored for up to 5 years, counting from the date of release. But the prepared injection solution can be kept in the refrigerator for no more than 24 hours. After the specified time has expired, it is no longer recommended to use it.

If you dilute the bottle and use it only for inhalation, then it can be stored in a cold place for 2 days. You can also store a solution prepared for instillation into the ears or nose.

Source: http://www.syl.ru/article/171802/new_antibiotik-fluimutsil—instruktsiya-po-primeneniyu-i-otzyivyi

Fluimucil effervescent tablets: instructions for use

The drug Fluimucil belongs to the group of mucolytic agents with antioxidant effects.

Release form and composition

The drug Fluimucil is available in the form of effervescent tablets in blisters of 2, 5, 10 pieces in a cardboard box. The drug comes with instructions with a detailed description. The tablets are round, large, white in color with a distinct lemon smell.

Each tablet contains 600 mg of the active ingredient - Acetylsteine, as well as a number of auxiliary components: sodium bicarbonate, citric acid, lemon flavor, aspartame. When the tablet is dissolved in water, a carbonated solution with the taste and smell of lemon is obtained.

Indications for use

Fluimucil tablets are prescribed to patients as part of complex therapy to thin and facilitate sputum discharge in the following diseases:

The drug can also be prescribed to stimulate expectoration of accumulated sputum in patients after surgery.

Contraindications

Before you start taking the drug, you should be sure to read the accompanying instructions, since effervescent tablets have a number of contraindications:

  • exacerbation of chronic erosive gastritis, gastric and duodenal ulcers;
  • breastfeeding period;
  • pregnancy 1st trimester;
  • age under 18 years for this dosage form of the drug;
  • hypersensitivity to acetylsteine;
  • simultaneous therapy with antitussive drugs.

With particular caution, effervescent tablets should be prescribed to patients suffering from varicose veins, bronchial asthma, phenylketonuria, renal and liver failure, and pregnant women in the 2nd and 3rd trimesters.

Directions for use and dosage

The dose of the drug is determined by the doctor individually, as is the duration of treatment. According to the instructions, adult patients are prescribed 600 mg of the drug once a day. The tablet is placed in 1/3 glass of water and waited until completely dissolved, after which the resulting solution is drunk.

To avoid discomfort in the stomach, it is recommended to take the drug after meals.

Use during pregnancy and lactation

In the 1st trimester of pregnancy, the use of Fluimucil tablets is contraindicated for women, since therapy can negatively affect the process of formation of the child’s internal organs.

In the 2nd and 3rd trimesters of pregnancy, the use of effervescent tablets is possible only in case of serious indications, when the expected benefit to the mother outweighs the possible risk to the fetus.

During lactation, taking Fluimucil in the form of effervescent tablets is contraindicated, since Acetylsteine ​​can be excreted in breast milk. If therapy is necessary, the woman should stop breastfeeding.

Side effects

When using effervescent tablets in patients with hypersensitivity to the components of the drug, some side effects may develop:

  • from the digestive system - belching, heartburn, cutting pain in the stomach, nausea, heaviness in the epigastric area, vomiting;
  • bronchospasm;
  • skin rash, angioedema, urticaria;
  • in rare cases, the development of acute vascular insufficiency, noise and ringing in the ears.

Overdose

Cases of overdose with Fluimucil effervescent tablets have not been described, but you should not deliberately exceed the recommended dose in order to avoid the development of negative effects on the organs of the digestive canal.

Interaction with other drugs

Fluimucil tablets should not be prescribed simultaneously with antitussives and tablets that suppress the functioning of the cough center. This leads to congestion and blockage of the airways with mucus.

If necessary, the drug in the form of effervescent tablets can be combined with mucolytics and expectorants of plant origin.

When the drug is prescribed simultaneously with tetracyclines, a decrease in the therapeutic effect of both groups of drugs is observed.

Under the influence of Acetylsteine, the hepatotoxic effect of Paracetamol is reduced.

special instructions

Patients with bronchial asthma are treated with the drug with caution due to the risk of worsening asthmatic attacks. If therapy is necessary, the patient's condition and the course of bronchial asthma should be carefully monitored.

The drug contains aspartame, so effervescent tablets should not be prescribed to patients with phenylketonuria. The tablet should be dissolved immediately before use, using glass containers for this purpose.

Analogs of effervescent tablets Fluimucil

Analogues of the drug Fluimucil in the form of effervescent tablets are:

  • ACC effervescent tablets;
  • Acetylsteine ​​tablets;
  • ACC long;
  • Vicks active expectomed tablets.

Conditions for release from pharmacies and storage

The drug Fluimucil is approved for over-the-counter dispensing from pharmacies. The tablets should be stored in a well-ventilated, dry place, out of reach of children and sunlight. The shelf life of the tablets is 3 years from the production date, after which the drug must be disposed of.

Fluimucil effervescent tablets price

The average price of Fluimucil effervescent tablets in Moscow pharmacies is 150 rubles.

Source: http://bezboleznej.ru/fluimutsil-shipuchiye-tabletki

Fluimucil ® (Fluimucil ® )

Active substance:

Content

Pharmacological group

Nosological classification (ICD-10)

3D images

Composition and release form

in sachets of 1 g; There are 30 sachets in a cardboard pack.

in sachets of 1 g; There are 20 sachets in a cardboard pack.

in a strip 2 pcs.; There are 5 or 10 strips in a cardboard pack.

10 pcs per strip; in a cardboard pack 1 or 2 strips.

in dark glass ampoules of 3 ml; There are 5 ampoules in a cardboard pack in a plastic holder.

pharmachologic effect

Liquefies mucus. The presence of sulfhydryl groups in the structure of acetylcysteine ​​promotes the rupture of disulfide bonds of acidic mucopolysaccharides of sputum, which leads to depolymerization of mucoproteins and a decrease in mucus viscosity. The drug remains active in the presence of purulent sputum.

Acetylcysteine ​​has an antioxidant effect due to the presence of a nucleophilic thiol SH group, which easily donates hydrogen, neutralizing oxidative radicals.

Pharmacodynamics

With the prophylactic use of acetylcysteine, there is a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis. The protective mechanism of acetylcysteine ​​is based on the ability of its reactive sulfhydryl groups to bind chemical radicals.

Acetylcysteine ​​easily penetrates into the cell and is deacetylated to L-cysteine, from which intracellular glutathione is synthesized. Glutathione is a highly reactive tripeptide, a powerful antioxidant, cytoprotector that traps endogenous and exogenous free radicals and toxins.

Acetylcysteine ​​prevents exhaustion and helps increase the synthesis of intracellular glutathione, which is involved in the redox processes of cells, i.e. promoting the detoxification of harmful substances. This explains the effect of acetylcysteine ​​as an antidote for paracetamol poisoning.

Pharmacokinetics

Fluimucil is well absorbed when taken orally. It is immediately deacetylated to cysteine ​​in the liver. In the blood there is a dynamic balance of free acetylcysteine ​​and its metabolites (cysteine, cystine, diacetylcystine) bound to plasma proteins. Due to the high “first pass” effect through the liver, the bioavailability of acetylcysteine ​​is about 10%. Acetylcysteine ​​penetrates into the intercellular space and is predominantly distributed in the liver, kidneys, lungs, and bronchial secretions.

After oral administration of 600 mg of acetylcysteine ​​to healthy volunteers, Cmax in plasma is reached after approximately 1 hour and is 15 mmol/l, with intravenous administration - 300 mmol/l. T1 /2 from plasma - 2 hours. Acetylcysteine ​​and its metabolites are excreted mainly by the kidneys.

Indications of the drug Fluimucil ®

Respiratory diseases accompanied by the formation of high-viscosity sputum (acute and chronic bronchitis, pneumonia, bronchiectasis, cystic fibrosis, bronchial asthma).

Contraindications

Hypersensitivity to acetylcysteine, peptic ulcer of the stomach and duodenum in the acute stage, age under 18 years (effervescent tablets).

Use during pregnancy and breastfeeding

Use during pregnancy and breastfeeding is only possible if the intended benefit to the mother outweighs the potential risk to the fetus or child.

Side effects

When taken orally, in rare cases, nausea, heartburn, vomiting, diarrhea, skin rash, itching, urticaria, nosebleeds, and tinnitus are possible. Cases of the development of bronchospasm, collapse, stomatitis, and decreased platelet aggregation have been described.

With parenteral administration - a slight burning sensation at the injection site, skin rash, urticaria.

With inhalation administration - reflex cough, local irritation of the respiratory tract, stomatitis, rhinitis, rarely - bronchospasm (bronchodilators are prescribed).

Interaction

The combined use of acetylcysteine ​​with antitussives may increase sputum stagnation due to suppression of the cough reflex.

When used simultaneously with antibiotics such as tetracyclines (excluding doxycycline), ampicillin, amphotericin B, they may interact with the thiol group of acetylcysteine, which leads to a decrease in the activity of both drugs. Therefore, the interval between taking these drugs should be at least 2 hours.

The simultaneous use of acetylcysteine ​​and nitroglycerin can lead to an increase in the vasodilating and disaggregating effects of the latter.

Acetylcysteine ​​eliminates the toxic effects of paracetamol.

Directions for use and doses

Granules for preparing a solution for oral administration : Dissolve in 1/3 glass of water.

For newborns - only for health reasons at a dose of 10 mg/kg under the strict supervision of a doctor. Children of the first year of life are given the resulting solution to drink from a spoon or feeding bottle.

Children from 1 year to 2 years - 100 mg 2 times a day, from 2 to 6 years - 200 mg 2 times a day or 100 mg 3 times a day, over 6 years old and adults - 200 mg 2-3 once a day.

The duration of treatment should be assessed individually. For acute diseases, the duration of treatment is from 5 to 10 days and up to several months for the treatment of chronic diseases (as recommended by a doctor).

Effervescent tablets. 1 table dissolve in 1/3 glass of water and take 1 time per day.

The duration of treatment should be assessed individually. For acute diseases, the duration of treatment is from 5 to 10 days and up to several months for the treatment of chronic diseases (as recommended by a doctor).

Injection

Parenteral administration. Adults, deep intramuscularly or intravenously - usually 300 mg (1 ampoule of 3 ml) 1-2 times a day.

Children 6–14 years old - 1/2 dose for adults. The daily dose for children under 6 years of age is 10 mg/kg. The duration of treatment should be determined based on the results of changes in the patient's condition. High local and general tolerance to the drug allows for long courses of treatment.

Inhalations: usually 300 mg (1 ampoule) 1–2 times a day for 5–10 days or longer courses; the frequency of administration and dose size can be changed by the doctor depending on the patient’s condition and the therapeutic effect. Children and adults - the same dosage.

Endobronchial administration: Injected appropriately using indwelling tubes, bronchoscope, etc. 300–600 mg (1–2 ampoules) or more per day depending on clinical indications.

Overdose

Acetylcysteine, when taken in doses of 500 mg/kg per day, did not cause signs and symptoms of overdose.

Precautionary measures

Prescribed with caution to patients prone to pulmonary hemorrhage, hemoptysis, with liver disease, kidney disease, adrenal dysfunction, patients with bronchial asthma and obstructive bronchitis (and under systematic monitoring of bronchial patency).

When dissolving acetylcysteine, you must use glass containers and avoid contact with metal and rubber surfaces. When opening the package, there may be a smell of sulfur; this is the smell of the active substance, and not evidence of poor quality of the drug.

The Fluimucil ampoule is opened before use. An opened ampoule can be stored in the refrigerator for 24 hours. Using the drug from a previously opened ampoule for injection is prohibited.

Fluimucil solution should not come into contact with rubber and metal surfaces.

special instructions

The drug contains aspartame, so it is not recommended for use in patients with phenylketonuria (granules, effervescent tablets).

Storage conditions for the drug Fluimucil ®

Keep out of the reach of children.

Shelf life of the drug Fluimucil ®

solution for injection and inhalation 100 mg/ml - 5 years.

effervescent tablets 600 mg - 3 years.

granules for the preparation of a solution for oral administration 100 mg with orange flavor or aroma - 3 years.

granules for the preparation of a solution for oral administration 200 mg with orange flavor or aroma - 3 years.

Do not use after the expiration date stated on the package.

Synonyms of nosological groups

Prices in Moscow pharmacies

The information is intended solely for comparing prices in stationary pharmacies operating in accordance with Article 55 of the Federal Law “On the Circulation of Medicines” dated April 12, 2010 N 61-FZ.

effervescent tablets 600 mg, 10 pcs.

Zambon Switzerland Ltd (Switzerland)

effervescent tablets 600 mg, 10 pcs.

Zambon Switzerland Ltd (Switzerland)

effervescent tablets 600 mg, 10 pcs.

Zambon Switzerland Ltd (Switzerland)

effervescent tablets 600 mg, 20 pcs.

Zambon Switzerland Ltd (Switzerland)

effervescent tablets 600 mg, 20 pcs.

Zambon Switzerland Ltd (Switzerland)

oral solution 20 mg/ml, 1 pc.

Zambon SPA (Italy)

oral solution 40 mg/ml, 1 pc.

Zambon SPA (Italy)

solution for injection and inhalation 100 mg/ml, 5 pcs.

Zambon SPA (Italy)

granules for the preparation of a solution for oral administration 200 mg with orange flavor or aroma, 20 pcs.

Zambon Switzerland Ltd (Switzerland)

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