What is ascoril

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Ascoril (tablets, syrup) – instructions for use, analogues, reviews, price

Composition and release form

1. Flat, round, white tablets, scored for easy separation.

There are 10 or 20 tablets in a package.

Table of contents:

Active ingredients: salbutamol, bromhexine hydrochloride, guaifenesin.

Excipients: microdoses of calcium hydrogen phosphate, corn starch, methylparaben, propylparaben, purified talc, silicon dioxide, magnesium stearate.

Active ingredients: salbutamol, bromhexine hydrochloride, guaifenesin, menthol

Excipients: microdoses of sucrose, sorbitol, glycerol, propylene glycol, sodium benzoate, citric acid, sorbic acid, sunset yellow dye, menthol, blackcurrant flavor, pineapple flavor and purified water.

pharmachologic effect

Indications for use

  • bronchial asthma;
  • tracheobronchitis (acute inflammation of the tissues of the trachea and bronchi);
  • obstructive bronchitis (restriction of air flow in the respiratory tract);
  • pneumonia (inflammation of lung tissue) without specifying the pathogen;
  • emphysema (increased air content in the lung tissue);
  • whooping cough (acute infection with spasmodic cough);
  • pneumoconiosis (occupational lung disease due to inhalation of industrial dust);
  • pulmonary tuberculosis confirmed by histological analysis;
  • pulmonary tuberculosis not confirmed by histological or bacteriological analysis;
  • acute or chronic bronchitis;
  • cystic fibrosis (severe dysfunction of the respiratory system).

Ascoril - instructions for use

Adults - 1 tablet 3 times a day, children over 6 years old - 0.5 tablets 2-3 times a day. Tablets are not prescribed to children under 6 years of age due to the risk of overdosing.

Adults - 10 ml, children under 6 years old - 5 ml, 6-12 years old - 5-10 ml. The frequency of administration is 3 times a day.

Askoril for children

The standard course of taking syrup for children is 5-7 days.

Ascoril is not prescribed to children under 1 year of age.

Contraindications

  • heart rhythm disturbances;
  • myocarditis (damage to the heart muscle due to inflammation);
  • aortic stenosis (narrowing of the opening of the cardiac aorta);
  • arterial hypertension.

1. Hyperthyroidism (increased function of the thyroid gland).

2. Decompensated diabetes mellitus (diabetes that cannot be treated with medications).

Prescribed with caution to patients with diabetes mellitus, and during remission of gastric and duodenal ulcers (weakening or disappearance of symptoms of the disease).

Drug interactions and overdose

2. Diuretics (Veroshpiron, Diakarb, Furosemide, Lasix) and glucocorticosteroids (Diprospan, Nasonex, Flixonase, Kenalog, Prednisolone, Solu-Medrol) enhance the ability of salbutamol to lower the concentration of potassium in the blood.

3. Ascoril is not recommended for patients taking monoamine oxidase inhibitors (Iproniazid, Nialamid, Moclobemide, Pirlindol, etc.).

4. Simultaneous use of Ascoril with drugs containing codeine and other cough medications makes it difficult to separate liquefied sputum. Therefore, when taking the drug, read the instructions for the medications you are already taking.

5. Concomitant use of the drug with non-selective beta-adrenergic receptor blockers (Propranolol, Anaprilin, Korgard, Trazicor, Sotalex) is not recommended.

6. The drug component Bromhexine promotes the penetration of antibiotics (Cefazolin, Macropen, etc.) into the lung tissue.

Side effects

Changes in the central nervous system:

Changes in the digestive organs:

From the cardiovascular system:

Allergic reactions due to sensitivity to active substances: skin rashes, itching.

special instructions

Use for various pathologies

  • functional liver disorders;
  • functional kidney disorders;
  • severe disorders of the cardiovascular system.

You should not prescribe the drug if the possibility of a negative reaction from using the drug outweighs its effectiveness.

Analogs

Reviews

How much does Ascoril cost?

  • The average price for Ascoril No. 10 tablets is 169 – 180 rubles;
  • Ascoril No. 20 tablets – rubles;
  • Ascoril No. 50 tablets – rubles;
  • Ascoril 100 ml syrup – rubles;
  • Ascoril 200 ml syrup – rubles.

Shelf life and storage conditions

Before using the drug, be sure to consult your doctor.

Read more:
Reviews

Guys, at least when you troll, change the style, otherwise the text looks like a carbon copy))

Ascoril is a good drug, but, of course, you need to take it as prescribed by your doctor.

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Source: http://www.tiensmed.ru/news/askoril-cw3.html

Ascoril - instructions for use, analogs, reviews and release forms (tablets, expectorant syrup) of a medicinal product for the treatment of cough as a symptom of bronchitis, pneumonia in adults, children and pregnancy. Compound

In this article you can read the instructions for use of the drug Ascoril. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Ascoril in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Ascoril in the presence of existing structural analogues. Use for the treatment of cough as a symptom of bronchitis, pneumonia in adults, children, as well as during pregnancy and lactation. Composition of the drug.

Ascoril is a combined drug that has a bronchodilator, expectorant and mucolytic effect.

Salbutamol is a bronchodilator that stimulates beta2-adrenergic receptors of the bronchi, blood vessels and myometrium. Prevents or eliminates bronchospasm, reduces resistance in the respiratory tract, increases the vital capacity of the lungs. Causes dilatation of the coronary arteries, does not reduce blood pressure.

Bromhexine is a mucolytic agent that has an expectorant and antitussive effect. Increases the serous component of bronchial secretions; activates the cilia of the ciliated epithelium, reduces the viscosity of sputum, increases its volume and improves discharge.

Guaifenesin is a mucolytic agent that reduces the surface tension of the structures of the bronchopulmonary apparatus; stimulates secretory cells of the bronchial mucosa that produce neutral polysaccharides, depolymerizes acidic mucopolysaccharides, reduces the viscosity of sputum, activates the ciliary apparatus of the bronchi, facilitates the removal of sputum and promotes the transition of an unproductive cough to a productive one.

Salbutamol (in the form of sulfate) + Bromhexine hydrochloride + Guaifenesin + excipients.

When taken orally, absorption is high. Eating reduces the rate of absorption but does not affect bioavailability. Penetrates through the placenta. Excreted by the kidneys (69-90%), mainly in the form of an inactive phenol sulfate metabolite (60%) within 72 hours and with bile (4%).

When taken orally, it is almost completely (99%) absorbed from the gastrointestinal tract within 30 minutes. Bioavailability is low (the effect of primary “passage” through the liver). Penetrates the placental barrier and the blood-brain barrier. Excreted by the kidneys. In chronic renal failure, the excretion of metabolites is impaired. May accumulate with repeated use.

Absorption from the gastrointestinal tract is rapid (within minutes after oral administration). T1/2 - 1 hour. Penetrates tissues containing acidic mucopolysaccharides. Approximately 60% of the administered drug is metabolized in the liver. It is excreted by the lungs (with sputum) and the kidneys, both unchanged and in the form of inactive metabolites.

As part of combination therapy for acute and chronic bronchopulmonary diseases accompanied by the formation of difficult-to-separate viscous secretions:

  • bronchial asthma;
  • tracheobronchitis;
  • obstructive bronchitis;
  • pneumonia;
  • emphysema;
  • whooping cough;
  • pneumoconiosis;
  • pulmonary tuberculosis.

Ascoril expectorant syrup (children's form of the drug).

Instructions for use and dosage regimen

Inside. Adults and children over 12 years of age are prescribed 1 tablet 3 times a day.

Children aged 6 to 12 years - 0.5 or 1 tablet 3 times a day.

For children under 6 years of age, it is recommended to use Ascoril Expectorant syrup.

Adults and children over 12 years of age are prescribed 10 ml (2 teaspoons) 3 times a day.

Children under 6 years old - 5 ml (1 teaspoon) 3 times a day, from 6 to 12 years - 5-10 ml (1-2 teaspoons) 3 times a day.

  • headache;
  • dizziness;
  • increased nervous excitability;
  • sleep disturbance;
  • drowsiness;
  • tremor;
  • convulsions;
  • nausea, vomiting;
  • diarrhea;
  • exacerbation of peptic ulcer of the stomach and duodenum;
  • cardiopalmus;
  • urine may turn pink;
  • allergic reactions (rash, urticaria);
  • collapse;
  • bronchospasm.
  • hypersensitivity to the components of the drug;
  • pregnancy;
  • lactation period;
  • tachyarrhythmia;
  • myocarditis;
  • heart defects;
  • decompensated diabetes mellitus;
  • thyrotoxicosis;
  • glaucoma;
  • liver or kidney failure;
  • peptic ulcer of the stomach and duodenum in the acute stage;
  • stomach bleeding;
  • arterial hypertension;
  • children under 6 years of age.

Use during pregnancy and breastfeeding

It is not recommended to use the drug during pregnancy.

If treatment with the drug is necessary during lactation, breastfeeding should be discontinued.

Ascoril expectorant is prescribed with caution to patients with hyperthyroidism, diabetes mellitus, severe diseases of the cardiovascular system, arterial hypertension, gastric and duodenal ulcers.

Ascoril expectorant should not be used in combination with beta-blockers.

Other beta2-adrenergic agonists and theophylline enhance the effect of salbutamol and increase the likelihood of side effects.

Ascoril is not prescribed simultaneously with drugs containing codeine and other antitussives, as this makes it difficult to clear liquefied sputum.

Bromhexine, which is part of the drug Ascoril, promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline) into the lung tissue.

It is not recommended to use Ascoril simultaneously with non-selective beta-adrenergic blockers, such as propranolol.

The drug Ascoril salbutamol, which is part of the drug, is not recommended for patients receiving MAO inhibitors.

Diuretics and glucocorticosteroids enhance the hypokalemic effect of salbutamol.

It is not recommended to take alkaline drinks at the same time as Ascoril.

Analogues of the drug Ascoril

The drug Ascoril has no structural analogues for the active substance.

Analogs in terms of therapeutic effects (secretolytics):

  • Ambroxol;
  • Amtersol;
  • Bromhexine;
  • Bronchicum;
  • Bronchipret;
  • Breast collection No. 1;
  • Chest collection No. 2;
  • Chest collection No. 3;
  • Breast Elixir;
  • Doctor IOM herbal cough lozenges;
  • Insti;
  • Cashnol;
  • Codelac Broncho with thyme;
  • Coldact Broncho;
  • Lazolvan;
  • Linkas Balm;
  • Cough mixture for adults, dry;
  • Dry cough syrup for children;
  • Ammonia-anise drops;
  • Expectorant collection;
  • Pectusin;
  • Pertussin;
  • Rinicold Broncho;
  • Stoptussin;
  • Sudafed;
  • Tussin Plus;
  • Eucatol.

Source: http://instrukciya-otzyvy.ru/261-askoril-po-primeneniyu-analogi-tabletki-sirop-ekspektorant-dlya-lecheniya-kashlya-bronhita-pnevmonii.html

Ascoril

Ascoril is a combined drug with bronchodilator and expectorant effects. It is used for the treatment of acute and chronic bronchopulmonary diseases accompanied by the formation of difficult-to-discharge viscous secretions and bronchospastic syndrome (bronchial asthma, bronchitis, tracheobronchitis, bronchiectasis, pulmonary emphysema, pneumonia, whooping cough, etc.).

Ascoril cough syrup is a combination drug that contains salbutamol, guaifenesin and bromhexine. The composition is selected in such a way that all components of the drug complement each other’s medicinal effect, enhancing it.

Ascoril: Instructions for use

Composition and release form

1 tablet Ascoril contains:

10 pcs. packaged.

Syrup Ascoril expectorant

10 ml of Ascoril expectorant syrup contains:

100 ml in bottles.

pharmachologic effect

The combined drug has a bronchodilator, expectorant and mucolytic effect. Salbutamol is a bronchodilator that stimulates beta2-adrenergic receptors of the bronchi, blood vessels and myometrium. Prevents or eliminates bronchospasm, reduces resistance in the respiratory tract, increases vital capacity. Causes expansion of the coronary arteries, does not reduce blood pressure. Bromhexine is a mucolytic agent that has an expectorant and antitussive effect. Increases the serous component of bronchial secretions; activates the cilia of the ciliated epithelium, reduces the viscosity of sputum, increases its volume and improves discharge. Guaifenesin is a mucolytic agent that reduces the surface tension of the structures of the bronchopulmonary apparatus; stimulates secretory cells of the bronchial mucosa that produce neutral polysaccharides, depolymerizes acidic mucopolysaccharides, reduces the viscosity of sputum, activates the ciliary apparatus of the bronchi, facilitates the removal of sputum and promotes the transition of an unproductive cough to a productive one.

Indications for use

Acute and chronic bronchopulmonary diseases, accompanied by the formation of difficult-to-discharge viscous secretions:

  • bronchial asthma;
  • tracheobronchitis;
  • obstructive bronchitis;
  • pneumonia;
  • emphysema;
  • whooping cough;
  • pneumoconiosis;
  • pulmonary tuberculosis.

etc. (as part of combination therapy).

Prescribe with caution to patients with diabetes mellitus, gastric and duodenal ulcers in remission.

Directions for use and doses

Syrup Ascoril expectorant

Orally, adults and children over 12 years of age are prescribed 10 ml (2 teaspoons) 3 times a day.

Children under 6 years old - 5 ml (1 teaspoon) 3 times a day, from 6 to 12 years old - 5-10 ml (1-2 teaspoons) 3 times a day. If necessary, the dose may be increased.

Inside. Adults and children over 12 years old - 1 tablet 3 times a day; children from 6 to 12 years old - 1/2 or 1 tablet 3 times a day.

For children under 6 years of age, it is recommended to use Ascoril Expectorant syrup.

Overdose

Symptoms: possible increased side effects.

Treatment: if necessary, carry out symptomatic therapy.

Contraindications

  1. individual intolerance (including a history of hypersensitivity) to the components of Ascoril;
  2. tachycardia, cardiac arrhythmias, tachyarrhythmia, myocarditis, heart defects;
  3. glaucoma;
  4. decompensated diabetes mellitus, thyrotoxicosis;
  5. liver or kidney failure;
  6. peptic ulcer of the stomach and duodenum in the acute stage;
  7. stomach bleeding;
  8. arterial hypertension;

Pregnancy and lactation

Adequate and strictly controlled clinical studies of the safety of Ascoril during pregnancy and lactation (breastfeeding) have not been conducted. In this regard, the use of Ascoril is possible only in cases where the potential benefit to the mother outweighs the expected risk to the fetus or child.

Side effect

Rarely: dyspeptic disorders, nausea, vomiting, diarrhea, exacerbation of gastric and duodenal ulcers, hand tremors, muscle cramps, allergic reactions (rash, urticaria).

When used in high doses - tachycardia, headache, dizziness, increased nervous excitability, sleep disturbance, drowsiness, peripheral vasodilation, decreased blood pressure, collapse.

Special instructions and precautions

Ascoril should be taken with caution in patients with hyperthyroidism, diabetes mellitus, severe diseases of the cardiovascular system, arterial hypertension, gastric and duodenal ulcers.

Drug interactions

When used simultaneously, sympathomimetics (beta2-adrenomimetic drugs) and theophylline enhance the effect and increase the likelihood of developing side effects of salbutamol, which is part of Ascoril.

Salbutamol, which is part of Ascoril, is not recommended for patients receiving MAO inhibitors.

Diuretics and glucocorticosteroid preparations enhance the hypokalemic effect of salbutamol.

Ascoril should not be used in combination with beta-blockers such as propranolol.

Ascoril is not prescribed simultaneously with drugs containing codeine and other antitussives, because this makes it difficult to clear liquefied sputum.

Bromhexine, which is part of Ascoril, promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline) into the lung tissue.

It is not recommended to take alkaline drinks at the same time as Ascoril.

Of course, antibiotics are the main drugs in the treatment of pneumonia. In first place in use are antibiotics from the penicillin group.

First aid for Tracheobronchitis should include warm compresses, mustard plasters or cups to restore the drainage function of the bronchi - the ability to remove foreign particles and mucus from the bronchi. To do this, you need to soften your cough. In the first two days of tracheobronchitis, libexin or any other drug that contains codeine is usually used.

Apitherapy treats diseases in the following areas: neurology, rheumatology, dermatology, endocrinology, surgery, eye diseases, urology, gynecology, cardiology, otolaryngology.

Pneumonia is an acute infectious disease in which the formation of an inflammatory infiltrate in the lung parenchyma occurs, confirmed by x-ray. Typical signs of pneumonia include general intoxication syndrome and bronchopulmonary-pleural syndrome.

If antibiotics for bronchitis are prescribed without sputum culture, then, as a rule, drugs from a group of broad-spectrum antibiotics are prescribed. In this case, it is a group of penicillin or protected penicillin.

Acute bronchitis is an acute inflammation of the tracheobronchial tree. Based on the dysfunction of external respiration, bronchitis is divided into obstructive and non-obstructive bronchitis. Symptoms of acute bronchitis are harsh breathing, scattered dry wheezing.

All materials presented on the site are for informational and informational purposes only and cannot be considered a guide to treatment or the choice of certain treatments.

Do not self-medicate. At the first signs of a disease, consult a doctor; only a doctor has the competence to diagnose the disease and the right to prescribe medications.

The site administration and the authors of the articles are not responsible for any losses and consequences that may arise when using the site materials.

Source: http://site-zdorovie.ru/lekarstvennie-sredstva/askoril-instrukciya.htm

Syrup "Ascoril" for children: instructions for use

Ascoril is classified as a medicine that makes sputum more liquid, relaxes smooth muscles in the bronchial tree and provides an expectorant effect. Is it allowed to be treated with Ascoril in childhood? How often is the drug given to young patients and how long does such treatment last? How to give syrup to a child correctly - before or after meals? Let's look at these and other questions about the use of Ascoril in children.

Release form

Ascoril is produced in the form of syrup, packaged in 100 ml or 200 ml bottles. This is an orange transparent liquid that tastes good and has a specific aroma. A solid form of Ascoril is also available, which is a round white tablet with a score on it (the tablet can be divided according to it). One package contains 10, 20 or 50 pieces.

Compound

There are three active ingredients in Ascoril syrup:

  1. Salbutamol. It is presented in a dosage of 2 mg per 10 ml of medication.
  2. Bromhexine. In 10 milliliters of syrup, this ingredient in the form of hydrochloride contains 4 mg.
  3. Guaifenesin. 10 ml of the drug contains 100 mg of this substance.

Among the additional components, menthol is the most valuable. In addition, the syrup has added compounds such as citric acid, glycerol, sucrose, yellow color, pineapple and blackcurrant flavors, sodium benzoate, sorbic acid, purified water, sorbitol and propylene glycol.

The active ingredients in Ascoril tablets are the same, but in addition, to obtain a solid form, propylparaben, Mg stearate, purified talc, Ca hydrophosphate, corn starch, methylparaben and silicon dioxide were added to the drug.

You might find this video useful, in which Dr. Komarovsky talks in detail about such a common childhood ailment as cough:

Operating principle

The influence of Ascoril on the human body is due to the therapeutic effect of each of its components:

  • Salbutamol has the ability to relax smooth muscles located in the walls of the bronchi by stimulating adrenergic receptors. Thanks to this action, the medicine eliminates spasm of the bronchial tree or prevents its occurrence. Since salbutamol affects beta 2 adrenergic receptors, among the effects caused by taking Ascoril there is not only relaxation of the bronchi and improvement of their patency, but also dilation of blood vessels. This component also has a positive effect on lung capacity.
  • The main effect of bromhexine is mucolytic. This ingredient in Ascoril helps with coughs, making sputum less thick and also increasing its volume. In addition, this compound activates the ciliated epithelium in the bronchi. As a result, mucus leaves the bronchial tree faster (it is better expectorated).
  • The effect of guaifenesin is also to reduce the viscosity of sputum and increase its quantity. Also, this component of the drug activates the areas of the bronchi responsible for removing mucus from the bronchial tree.
  • Menthol added to Ascoril syrup is also noted to have the ability to relax the bronchi and soothe coughs. This component helps to activate the secretion of glands in the bronchial tree and also has an antiseptic effect.

Indications

The reason to prescribe Ascoril is often a bronchopulmonary disease in which there are difficulties with sputum separation. The drug is prescribed:

  • With tracheobronchitis.
  • For any type of bronchitis.
  • For asthma.
  • With laryngotracheitis.
  • For pneumonia (inflammation of lung tissue) caused by any pathogen.
  • For obstructive pulmonary disease.
  • For whooping cough, when the patient has a strong spasmodic cough that gets worse at night.
  • With emphysema.
  • For tuberculosis lung infection.
  • For cystic fibrosis.

At what age is it allowed to take it?

In pediatrics, Ascoril in syrup form is used in children over 1 year of age. At 6 months and other ages up to one year, this medicine is not prescribed. But even if the child is older, for example, he is already 3 years old, the use of Ascoril syrup should be very careful.

If the drug is given for a wet cough, the excess phlegm that forms in the respiratory tract will only worsen the baby’s condition. But with a dry cough, when the mucus in the bronchi is too thick and viscous, Ascoril will be an effective help (it will make the cough productive). As for Ascoril tablets, they are not given until the age of 6.

Contraindications

The medicine is not prescribed:

  • If the child has a hypersensitivity to any of its ingredients.
  • If the patient has high blood pressure, myocarditis is diagnosed, heart rhythm is abnormal, or aortic stenosis is detected.
  • If the child's thyroid function is elevated.
  • If glaucoma is detected.
  • If a small patient has gastric bleeding or a peptic ulcer has worsened.
  • If your baby has diabetes mellitus in the stage of decompensation.
  • If kidney function is severely impaired or liver failure is detected.

In case of remission of a peptic ulcer or compensated diabetes mellitus, Ascoril should be used with caution.

Side effects

  • Allergies to the active or auxiliary substances of Ascoril occur, for example, in the form of skin rash or itching.
  • The urine of a child treated with Ascoril may take on a pink tint, which should not cause concern.
  • The child’s nervous system may react to taking Ascoril with sleep disturbances, headaches, drowsiness, tremor of the body or limbs, excitability and even convulsions.
  • Treatment with Ascoril may cause diarrhea, nausea, bloating and other symptoms of dyspepsia.
  • Under the influence of Ascoril, a biochemical blood test can be unreliable.
  • The drug can cause a decrease in blood pressure, as well as an increase in heart rate.
  • In very rare cases, when taking Ascoril, bronchospasm, retraction of the wings of the nose, severe pallor and dry wheezing in the lungs occur. This is a paradoxical reaction to the drug, which is caused by individual intolerance.

Watch a video interview with a practicing pediatrician, who will talk about mucolytic drugs used in pediatrics:

Instructions for use and dosage

  • The syrup should be drunk about a minute after eating. The medicine is given three times a day. It is better to drink the product with water, and liquids such as milk with added soda or mineral water can reduce the therapeutic effect of Ascoril due to the presence of alkalis.
  • The dosage of syrup for a child under six years of age is 5 ml per dose, and for children aged 6 to 12 years, liquid Ascoril can be given either 5 or 10 ml at a time. Children 12 years of age and older are offered an adult dosage, which is 10 ml of syrup per dose.
  • Ascoril tablets should also be taken some time after meals with a non-alkaline liquid. A single dose for children is half a tablet, given twice a day. If necessary, the frequency of doses is increased to three times a day.
  • How many days should I take Ascoril Expektorant? Most often, the course of treatment with this drug lasts 5 or 7 days, but sometimes the doctor extends the period of use of Ascoril.

Overdose

If you give your child Ascoril in a dose greater than the recommended dose or are treated with this drug for longer than the doctor prescribed, this will lead to an overdose, which will manifest itself as increased side effects of the drug.

Interaction with other drugs

  • If Ascoril is used together with other drugs that act on the same adrenergic receptors, for example, with Berodual, Anaprilin, Ventolin, Propranolol or Clenbuterol, then their therapeutic effect will increase, but the side effects will be more pronounced.
  • Prescribing Ascoril together with glucocorticoids or diuretics will provoke a decrease in potassium levels in the blood.
  • The drug should not be combined with antidepressants, which are classified as MAOIs.
  • The simultaneous use of Ascoril and antitussive medications (especially those based on codeine) will interfere with sputum production and worsen the child’s condition.
  • The addition of Ascoril to treatment with Macropen, Cefazolin and some other antibiotics will promote greater penetration of such antimicrobial agents into the lung tissue.

Terms of sale

To buy Ascoril expectorant or the tablet form of the drug in a pharmacy, you need a prescription from a doctor. The price of 100 ml of syrup is on average 300 rubles, and a 200 ml bottle is approximately 400 rubles. A pack of 10 tablets costs about 240 rubles.

Storage conditions and shelf life

The place where you plan to store Ascoril must be ventilated, dry and away from sunlight. Do not keep the drug where it can be easily reached by a small child. It is advisable that the air temperature in the place chosen for storage does not exceed +25°C. Both syrup and tablets have a shelf life of 2 years.

Reviews

Mothers leave many positive reviews about the use of Ascoril in the treatment of dry cough in children. According to them, the product very effectively thins mucus and helps remove it from the bronchi. The fact that such a medicine helps quite quickly is also evidenced by the opinions of doctors. Many pediatricians note that a course of treatment with Ascoril for 5-7 days is often enough to get rid of cough.

Parents point out that the disadvantages of Ascoril syrup are quite common side effects (many note headaches, tremors, rapid pulse, weakness and nausea) and the presence of chemical additives in the composition. Also, some children do not like the taste of this drug, because it is bitter-sweet.

Analogs

If Ascoril is prescribed to a child, but it is not possible to give this medicine for one reason or another, the question naturally arises of what to replace such a drug with. A similar effect is observed in the following drugs:

  • Cashnol. This syrup is a complete analogue of Ascoril in composition and content of active substances. It comes in the form of a red liquid with raspberry flavor, which is sold in 100 ml and 200 ml bottles. The indications for use and doses of this drug are exactly the same as Ascoril in syrup.
  • Erespal. This medication, which is based on the antihistamine compound fenspiride, helps eliminate bronchospasm and reduce inflammation. It is prescribed for laryngitis, whooping cough, flu, sinusitis, asthma and other pathologies. Erespal is presented in syrup (prescribed from the age of 2) and film-coated tablets (not used under the age of 18). It is acceptable to take Erespal and Ascoril at the same time, because such drugs act on different receptors.
  • Lazolvan. This expectorant drug contains ambroxol (the same active ingredient is found in the drug Ambrobene). It is produced in syrup with different concentrations of the active component, in a solution for inhalation or internal use, and also in tablets. Ambroxol preparations are prescribed to children from birth, but under the supervision of a specialist in the first year of life.
  • ACC. This popular mucolytic containing acetylcysteine ​​is effective against too viscous sputum. The product is available in different dosages and in different forms (packets of powder for preparing a suspension, syrup, effervescent tablets). It is prescribed from 2 years of age.
  • Fluditek. The basis of this mucolytic drug is carbocisteine. The remedy is in demand for otitis media, sinusitis, tracheitis and other diseases. For children, the drug is available in syrup with a reduced dosage (20 mg of active substance per 1 ml). It is prescribed from the age of 2 years, and a medicine with a higher dose (50 mg/ml) is allowed from the age of 15.
  • Gedelix. This medicine in drops or syrup has an expectorant effect and is prescribed to children 2 years of age and older. The drug has a plant base, represented by an extract from ivy leaves.
  • Tussin. The active ingredient in this syrup is guaifenesin. The drug can be given to people over two years of age.

Although all such drugs have a similar therapeutic effect, if it is impossible to treat with Ascoril, the question is “what is better to replace it?” You should decide with your pediatrician, because each of these medications differs in composition, list of contraindications, and other features. In addition, depending on the illness, the child will need other medications, for example, antipyretics for fever.

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"Ascoril": instructions for use, analogues and reviews from doctors

Nowadays, the choice of expectorants is huge, and sometimes, when you go to a pharmacy, it is very difficult to decide, because your eyes run wide from the many offers. Today we will consider an effective drug called “Ascoril”: its composition, instructions, side effects, contraindications for use, as well as reviews from patients and doctors about the effect of this medicine.

Medicinal components of the product

The main elements that help get rid of dry cough and are present in the drug we describe are:

- Menthol. The task of this component is to expand the bronchi and, as a result, improve breathing, as well as the discharge of sputum through the respiratory tract. Another advantage of this element is that it is of natural origin and not chemical.

— Guaifenesin is a special plant substance that is obtained from the bark of the guaiac tree. The effect of this component is as follows: it significantly reduces the viscosity of sputum. The substance makes it less thick and thanks to this it comes out faster and easier.

— Bromhexine is another important component of the syrup or tablets called “Ascoril” for children and adults. It has a mucolytic, expectorant effect.

- Salbutamol. This is a bronchodilator that causes muscle relaxation and widens the airways. As a result, the patient’s breathing quickly returns to normal. But the downside of this component is that it can cause various side effects. This may be headache, tachycardia, dizziness, insomnia, nausea, vomiting, sweating, etc.

Composition and release form

1. In the form of tablets. Small pills are round, white, with special half markings for easy separation. Sold in cardboard packaging of 10 or 20 tablets.

Composition: main elements – salbutamol, bromhexine hydrochloride, guaifenesin. Additional substances: a small dose of calcium hydrogen phosphate, corn starch, methylparaben, propylparaben, purified talc, silicon dioxide, magnesium stearate.

2. In the form of a carrot-colored syrup with a characteristic odor and bittersweet taste. The volume of the bottle is 100 or 200 ml. The composition is similar to the contents of the tablets, the active substances are similar, but the additional components are: a small dose of sucrose, sorbitol, glycerol, propylene glycol, sodium benzoate, citric acid, sorbic acid, dye, menthol, blackcurrant, pineapple flavoring, purified water.

In what cases is it prescribed

The drug "Ascoril", the instructions for use of which provide accurate and detailed information, is prescribed in a number of such cases:

  1. Diseases of the bronchi, as well as the lungs, which are accompanied by coughing attacks and sputum production: pneumonia, bronchitis, bronchial asthma.
  2. For whooping cough, a severe infectious disease of the respiratory tract.
  3. Pulmonary tuberculosis is a dangerous disease that is very difficult to treat.
  4. Cystic fibrosis is a congenital pathology in which the functions of the respiratory organs are impaired.

The drug "Ascoril": instructions. Syrup for children and tablets for adults

The medication has a very good effect in treating dry cough in children. Only in different children's age categories the form of release of the medicine differs. So, children under the age of 6 years are prescribed “Ascoril” - cough syrup, and from 6 years old you can give the same medication, only in tablets. Little toddlers are not prescribed pills due to the possible risk of overdose. The dosage of the medicine for children is as follows:

In the form of a mixture:

- up to 6 years - 5 ml three times a day;

- from 6 to 12 years - 5-10 ml per day;

- from 12 years old - 10 ml three times a day.

- from 6 to 12 years - half a tablet three times a day;

- from 12 years - a whole pill three times a day.

For adults, the medicine is also prescribed in the same dosage as for the younger generation after 12 years.

It is advisable to take the medicine on a full stomach, about half an hour to an hour after eating. It is not recommended to drink the drug with mineral water with bicarbonate or milk with soda, as this reduces the effectiveness of the therapeutic effect. It is best to use ordinary purified water for this purpose.

The standard course of treatment is 5–7 days.

Use during pregnancy

Pregnant women, as well as nursing mothers, should not treat dry cough with this remedy. In this case, therapists prescribe other effective medications of natural origin that will definitely not cause side effects to the pregnant woman and her unborn child.

Storage conditions

The medicine should be stored at a temperature no higher than 25 degrees. The expiration date must be indicated on the packaging, and it is 2 years from the date of manufacture of the drug. It is advisable to store the suspension and tablets in a dark place, with low air humidity and always away from children so that they cannot reach and drink the contents of the bottle or swallow the pill after removing it from the blister.

Contraindications for use

A mixed product of plant and chemical origin that copes well with coughs is Ascoril syrup. The instructions for use of the drug state that it should not be used by persons with the following health conditions:

- hypersensitivity to the components of the drug;

- pregnancy and the period when a woman is breastfeeding a baby;

- liver or kidney failure;

- gastric or duodenal ulcer in the acute stage;

If a person has one of the diseases described above, then the patient needs to replace the medication “Ascoril”. You won’t find tablets or syrup with a similar composition, but there are many effective alternatives for treating dry cough, which we will discuss below.

Drugs with similar effects

Many people are interested in what can replace the medicine “Ascoril”. Analogs of this mixture are as follows: syrups “Lazolvan”, “Ambrobene”, “Erespal”. But there are still differences in composition. If the cough medicine “Ascoril” is an expectorant, that is, it helps to cope with a dry cough, then the “Lazolvan” solution can be used at any stage of the disease. If we compare our medicine with the Ambrobene mixture, then there is no difference in their effects. The only difference is the cost of the drugs. “Ascoril” (syrup) is much more expensive than its analogue. The medicine Erespal has the same effect, but the remedy to which the article is devoted is much cheaper.

Analogues of Ascoril tablets can be:

- Dragee "Mukaltin". It is an expectorant, increases the amount of sputum and reduces its viscosity. The drug is much cheaper than the drug described. Prescribed for children over 12 years of age, as well as for adults.

— Tavipex capsules. This is also an inexpensive analogue of Ascoril tablets, which can only be taken by adults; children under three years old should not be given it.

— Gedelix capsules. They have a minimum of side effects, are cheaper than the drug described, and are prescribed from 12 years of age.

Overdose

Taking large doses exceeding those recommended in the instructions, as well as using the drug for longer than prescribed, can cause an overdose of the drug. In this case, you must immediately stop drinking the drug and take measures aimed at alleviating the condition: rinse the stomach and take enterosorbents, for example: Enterosgel gel, activated carbon tablets. Symptoms of an overdose may be: nausea, vomiting, rapid heartbeat, low blood pressure, confusion. If a person has any problems with the heart, then he definitely needs a consultation with a therapist, as well as monitoring by a cardiologist.

Side effects of taking the drug

Taking medication does not always lead to a positive result. It happens that people experience side effects; negative consequences are mainly associated with the use of salbutamol, which is part of the drug Ascoril. The instructions for using syrup or tablets state that unexpected effects of the medicine on the human body may occur. The most common reactions observed are:

- unhealthy rapid heartbeat.

Less commonly, the following may occur:

- decrease in potassium concentration in the blood.

Very rarely, but still such reactions occur:

All these negative aspects can be observed in adults after treatment with Ascoril. The use of the suspension to treat children can also cause various side effects, such as:

- formation of red spots on the skin (usually on the face, less often on the torso and limbs);

- blisters on the mucous membranes of the mouth, throat, eyes, genitals;

- taste disorder (in this condition, food seems bitter to babies);

- feeling of numbness, tingling in the mouth;

- decrease or increase in blood pressure;

- increase in blood insulin levels.

Interaction of the drug with other medications

There are certain rules according to which Ascoril tablets or cough syrup cannot be prescribed with other drugs. The instructions for use indicate that in the following situations you should refrain from using this medication:

  1. If the patient is taking medications containing theophylline. They can enhance the effect of salbutamol, which is part of the medicine described in this article. And this, in turn, threatens a number of side effects.
  2. Ascoril expectorant should not be taken simultaneously with other medications that contain codeine or any other cough medicines, as this makes it difficult to clear liquefied sputum.
  3. It is not recommended to take this medicine at the same time as drinking an alkaline drink.
  4. The use of the drug together with non-selective beta-adrenergic blockers, such as propranolol, is excluded.

Doctors' opinions on the use of medicine

Many parents are concerned about the fact that the drug contains a lot of dyes and flavors. Is it possible to use Ascoril (syrup) for children in this case? Pediatricians have different opinions on this matter. Some say that only safe additives are used in the manufacture of the medicine, so you can safely buy the product at the pharmacy. Other doctors are not so positive about the drug Ascoril. They leave reviews of the following nature: they say, even with an abundance of such additives, the taste of the syrup is bitter and not all children like it. In this case, they advise choosing a more “tasty” and effective analogue, for example, the Erespal mixture.

Another exciting question that parents ask when they come to see a pediatrician or go to the pharmacy for another expectorant is how safe this remedy is and will Ascoril syrup harm the patient? Reviews are again different. Some doctors reject unnecessary fears and concerns, even though the instructions for the medicine describe all possible side effects. Other doctors answer this question differently: the individual active components of the drug have been studied thoroughly and their effectiveness has been experimentally proven, and the risks of negative consequences are low. But in the case of complex drugs, which also include Ascoril cough syrup, it almost always happens that the combination of several elements not only enhances the positive effect of the drug, but also increases the number of contraindications. It follows that the drug can somehow harm a person, but it all depends on the specific characteristics of the body and certain conditions. Some patients take this medicine and tolerate it well, while others complain of various negative effects. But still, doctors recommend trying the medicine “Ascoril” first. Buying tablets or syrup at a pharmacy is at your discretion, but you should not be afraid of this drug in advance. Even if you experience any side effects, you can easily replace the medicine with a similar one, especially since there are a lot of options.

Parents' opinions about the drug "Ascoril"

Reviews from mothers about treating their children with this medicine are different. But still, most adequate parents have a positive opinion about him. According to their practice, the syrup really effectively helps to cope with a dry cough; the child begins to cough up mucus the very next day. After a week, their symptoms of the disease completely disappear. The price of this medication, although not low, is worth paying for a good result, parents believe, and there is no need to save on the child’s health. The opinions of other parents are negative. Firstly, they speak poorly of the drug because it allegedly does not cope with a wet cough, but only aggravates the situation. But the fact is that this syrup treats a dry cough, but not a wet one, in which case another medicine is prescribed. Secondly, some do not monitor the dosage of the drug and, instead of the prescribed 5 ml, give children more or more often, as a result of which a lot of negative consequences appear. Therefore, before reading such negative comments on the Internet, you should seek advice from a specialist who will give his recommendations on the use of the drug or prescribe another treatment. In any case, it is possible to treat a child for a dry cough with suspensions from a pharmacy only after consulting a pediatrician who will examine the baby, listen to him, make an accurate diagnosis and prescribe the appropriate appropriate treatment. Perhaps the doctor will recommend Ascoril as the main drug, or maybe he will recommend other syrups or tablets, but this will in no way mean that the medicine described in this article is bad or ineffective.

Now you know what a good remedy can be to cure a dry cough in a child or an adult. We found out the possible side effects of taking the drug, found out what the consequences of an overdose may be, and also remembered other analogues of this medicine that can replace the syrup if for some reason it is not possible to be treated with Ascoril suspension or tablets. The instructions for use of the medicine fully provide all the information regarding the medicine. Reviews about the drug are mostly positive, but there are also negative reviews that you can read, but not really delve into them, because without trying the effect of the product on yourself, it is impossible to say whether it is effective or not.

Source: http://www.syl.ru/article/161601/new_askoril-instruktsiya-po-primeneniyu-analogi-i-otzyivyi-vrachey

Ascoril

The tablets are white, round, flat, chamfered and scored on one side.

Excipients: calcium hydrogen phosphate, corn starch, methyl parahydroxybenzoate (methylparaben), propyl parahydroxybenzoate (propylparaben), purified talc, colloidal silicon dioxide, magnesium stearate.

10 pieces. — cellular contour packages (1) — cardboard packs.

10 pieces. — contour cell packaging (2) — cardboard packs.

10 pieces. — contour cell packaging (5) — cardboard packs.

A combined drug with bronchodilator, expectorant and mucolytic effects.

Salbutamol is a bronchodilator that stimulates β 2 -adrenergic receptors of the bronchi, blood vessels and myometrium. Prevents or eliminates bronchospasm, reduces resistance in the respiratory tract, increases the vital capacity of the lungs. Causes expansion of the coronary arteries, does not reduce blood pressure.

Bromhexine is a mucolytic agent, has an expectorant effect, improves sputum discharge.

Guaifenesin is a mucolytic agent that reduces the surface tension of the structures of the bronchopulmonary apparatus; stimulates secretory cells of the bronchial mucosa that produce neutral polysaccharides, depolymerizes acidic mucopolysaccharides, reduces the viscosity of sputum, activates the ciliary apparatus of the bronchi, facilitates the removal of sputum and promotes the transition of an unproductive cough to a productive one.

Suction and distribution

When taken orally, absorption is high. The bioavailability of salbutamol when taken orally is about 50%. Eating reduces the rate of absorption but does not affect bioavailability. Plasma protein binding - 10%. Penetrates through the placental barrier.

Metabolism and excretion

Subjected to first-pass metabolism in the liver and in the intestinal wall, it is inactivated by phenolsulfotransferase to 4-o-sulfate ester. T1 /2 - 3.8-6 hours. Excreted by the kidneys (69-90%), mainly in the form of an inactive phenol sulfate metabolite (60%) within 72 hours and with bile (4%).

Suction and distribution

When taken orally, it is almost completely (99%) absorbed from the gastrointestinal tract within 30 minutes. Bioavailability is low (because it is subject to the “first pass” effect through the liver). Penetrates through the placental barrier and BBB.

Metabolism and excretion

In the liver it undergoes demethylation and oxidation, metabolized to the pharmacologically active ambroxol. T 1/2 - 15 hours (due to slow reverse diffusion from tissues). Excreted by the kidneys.

In chronic renal failure, the excretion of metabolites is impaired. May accumulate with repeated use.

Suction and distribution

Absorption from the gastrointestinal tract is rapid (within minutes after oral administration). Penetrates into tissues containing acidic mucopolysaccharides.

Metabolism and excretion

Approximately 60% of the administered drug is metabolized in the liver.

T 1/2 - 1 hour. Excreted by the lungs (with sputum) and the kidneys, both unchanged and in the form of inactive metabolites.

As part of combination therapy for acute and chronic bronchopulmonary diseases accompanied by the formation of difficult-to-separate viscous secretions:

The drug is taken orally.

Adults and children over 12 years of age are prescribed 1 tablet. 3 times/day or 10 ml of Ascoril expectorant syrup (2 teaspoons) 3 times/day.

Children aged 6 to 12 years – 1/2 or 1 tablet. 3 times/day or 5-10 ml of Ascoril expectorant syrup (1-2 teaspoons) 3 times/day.

For children under 6 years of age, it is recommended to use Ascoril expectorant syrup 5 ml (1 teaspoon) 3 times a day.

Rarely: when used in high doses, headache, dizziness, increased nervous excitability, sleep disturbance, drowsiness, tremor, convulsions, nausea, vomiting, diarrhea, exacerbation of gastric and duodenal ulcers, rapid heartbeat, possible pink coloration of urine are sometimes observed. , allergic reactions (rash, urticaria), collapse, bronchospasm.

- hypersensitivity to the components of the drug;

— pregnancy, lactation period;

— decompensated diabetes mellitus;

- liver or kidney failure;

- peptic ulcer of the stomach and duodenum in the acute phase;

- arterial hypertension (for the use of tablets);

- children under 6 years of age (for use of tablets).

with caution to patients with diabetes mellitus, gastric and duodenal ulcers in remission.

It is not recommended to use the drug during pregnancy.

If treatment with the drug is necessary during lactation, breastfeeding should be discontinued.

Symptoms: possible increased side effects.

Treatment: symptomatic therapy.

Other beta 2 -adrenergic agonists and theophylline enhance the effect of salbutamol and increase the likelihood of side effects.

Ascoril is not prescribed simultaneously with drugs containing codeine and other antitussives, because this makes it difficult to clear liquefied sputum.

Bromhexine, which is part of the drug Ascoril, promotes the penetration of antibiotics (erythromycin, cephalexin, oxytetracycline) into the lung tissue.

It is not recommended to use Ascoril simultaneously with non-selective beta-adrenergic receptor blockers, such as propranolol.

Salbutamol, which is part of the drug Ascoril, is not recommended for patients receiving monoamine oxidase inhibitors (MAOIs).

Diuretics and glucocorticosteroid preparations enhance the hypokalemic effect of salbutamol.

It is not recommended to take alkaline drinks at the same time as Ascoril.

The drug should be stored in a dry place, protected from light, at a temperature not exceeding 25°C. Keep out of the reach of children.

Shelf life: 2 years. Do not use after expiration date.

By doctor's prescription.

The scientific information provided is general and cannot be used to make a decision about the possibility of using a particular drug.

There are contraindications, consult your doctor.

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Source: http://health.yandex.ru/pills/askoril-21469